LOCUS       NM_018083               1968 bp    mRNA    linear   PRI 04-APR-2024
DEFINITION  Homo sapiens zinc finger protein 358 (ZNF358), mRNA.
ACCESSION   NM_018083
VERSION     NM_018083.5
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 1968)
  AUTHORS   Wride,M.A., Mansergh,F.C., Somani,J.M., Winkfein,R.J. and
            Rancourt,D.E.
  TITLE     Characterization and in silico mapping of a novel murine zinc
            finger transcription factor
  JOURNAL   Gene 289 (1-2), 49-59 (2002)
   PUBMED   12036583
REFERENCE   2  (bases 1 to 1968)
  AUTHORS   Bassi,M.T., Manzoni,M., Monti,E., Pizzo,M.T., Ballabio,A. and
            Borsani,G.
  TITLE     Cloning of the gene encoding a novel integral membrane protein,
            mucolipidin-and identification of the two major founder mutations
            causing mucolipidosis type IV
  JOURNAL   Am J Hum Genet 67 (5), 1110-1120 (2000)
   PUBMED   11013137
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC008878.10, BI601846.1, AK001252.2 and BC003585.1.
            
            On Nov 24, 2018 this sequence version replaced NM_018083.4.
            
            ##Evidence-Data-START##
            Transcript exon combination :: ERR279839.2952.1,
                                           SRR1163657.353982.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA1965299, SAMEA1966682
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000597229.2/ ENSP00000472305.1
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-15                AC008878.10        130027-130041
            16-279              BI601846.1         4-267
            280-1696            AK001252.2         43-1459
            1697-1968           BC003585.1         913-1184
FEATURES             Location/Qualifiers
     source          1..1968
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="19"
                     /map="19p13.2"
     gene            1..1968
                     /gene="ZNF358"
                     /gene_synonym="ZFEND"
                     /note="zinc finger protein 358"
                     /db_xref="GeneID:140467"
                     /db_xref="HGNC:HGNC:16838"
                     /db_xref="MIM:619496"
     exon            1..147
                     /gene="ZNF358"
                     /gene_synonym="ZFEND"
                     /inference="alignment:Splign:2.1.0"
     exon            148..1968
                     /gene="ZNF358"
                     /gene_synonym="ZFEND"
                     /inference="alignment:Splign:2.1.0"
     CDS             186..1892
                     /gene="ZNF358"
                     /gene_synonym="ZFEND"
                     /codon_start=1
                     /product="zinc finger protein 358"
                     /protein_id="NP_060553.4"
                     /db_xref="CCDS:CCDS32890.2"
                     /db_xref="GeneID:140467"
                     /db_xref="HGNC:HGNC:16838"
                     /db_xref="MIM:619496"
                     /translation="MRRSVLVRNPGHKGLRPVYEELDSDSEDLDPNPEDLDPVSEDPE
                     PDPEDLNTVPEDVDPSYEDLEPVSEDLDPDAEAPGSEPQDPDPMSSSFDLDPDVIGPV
                     PLILDPNSDTLSPGDPKVDPISSGLTATPQVLATSPAVLPAPASPPRPFSCPDCGRAF
                     RRSSGLSQHRRTHSGEKPYRCPDCGKSFSHGATLAQHRGIHTGARPYQCAACGKAFGW
                     RSTLLKHRSSHSGEKPHHCPVCGKAFGHGSLLAQHLRTHGGPRPHKCPVCAKGFGQGS
                     ALLKHLRTHTGERPYPCPQCGKAFGQSSALLQHQRTHTAERPYRCPHCGKAFGQSSNL
                     QHHLRIHTGERPYACPHCSKAFGQSSALLQHLHVHSGERPYRCQLCGKAFGQASSLTK
                     HKRVHEGAAAAAAAAAAAAAAAAAGLGLGPGLSPASMMRPGQVSLLGPDAVSVLGSGL
                     GLSPGTSSGRNPDPGSGPGTLPDPSSKPLPGSRSTPSPTPVESSDPKAGHDAGPDLVP
                     SPDLDPVPSPDPDPVPSPDPNPVSCPDPCSPTRGTVSPALPTGESPEWVQEQGALLGP
                     DG"
     regulatory      1944..1949
                     /regulatory_class="polyA_signal_sequence"
                     /gene="ZNF358"
                     /gene_synonym="ZFEND"
                     /note="hexamer: AGTAAA"
     polyA_site      1968
                     /gene="ZNF358"
                     /gene_synonym="ZFEND"
                     /note="major polyA site"
ORIGIN      
        1 ccctctcgct ccccgggagc gcctggcggg gccgctgggc cgagggggcc gccggcgggg
       61 ctggcgggcg gggggcttcc tgcgggcccg gggggagccg gcggccggcg cgggcgcggc
      121 gggccgggca ggggcgaggg gcgccgggtc ttgccccaga agctgcgggc acatccacgc
      181 ctgaaatgcg gcgctcagtc ctggtcagga acccaggcca caaaggcctg agacccgttt
      241 atgaagagct cgactctgac tccgaggacc tagaccccaa tcctgaagat ctggacccgg
      301 tttctgaaga cccagagcct gatcctgaag acctcaacac tgtcccggaa gacgtggacc
      361 ccagctatga agatctggag cccgtctcgg aggatctgga ccccgacgcc gaagctccgg
      421 gctcggaacc ccaagatccc gaccccatgt cttcgagttt cgacctcgat ccagatgtga
      481 ttggccccgt acccctgatt ctcgatccta acagcgacac cctcagcccc ggcgatccaa
      541 aagtggaccc catctcctct ggcctcactg ccacccccca ggtcttggcc accagccccg
      601 cggtgctccc cgcccccgcc agcccgcccc ggcccttctc ctgcccggat tgcgggcgag
      661 ccttccgccg cagctccggg ctgagccagc atcgccgcac gcacagcggc gagaagccgt
      721 accgctgccc cgactgcggg aagtccttca gccacggtgc caccctggct cagcaccgtg
      781 gcatccacac tggggcgcgg ccgtaccagt gcgcggcctg cggcaaggcc ttcggctggc
      841 gctccacgct gctgaaacat cgcagcagcc acagcgggga gaagccgcac cactgcccgg
      901 tgtgtggcaa ggccttcggg cacggctcgc tcctggcaca gcacctgcgc acgcacggcg
      961 gcccgcggcc ccacaagtgc ccggtgtgcg ccaagggctt cggccagggc tctgcgctgc
     1021 tcaaacacct gcgcacgcac acgggcgagc ggccctaccc gtgtccgcag tgcggcaagg
     1081 ccttcgggca gagctcggcg ctgctgcagc accagcgcac acacacggcc gagcgcccct
     1141 accgctgccc ccactgcggc aaagccttcg ggcagagctc caacttgcaa caccacctgc
     1201 gcatccacac gggcgagcgg ccctacgcct gcccgcactg ctccaaggcc ttcggccaga
     1261 gctcagcgct gctccagcac ctgcacgtgc attcgggcga gcgtccctat cgctgtcagc
     1321 tctgcgggaa ggccttcggc caggcctcca gcctcaccaa gcacaaacgg gtgcatgagg
     1381 gtgcagccgc tgctgcagct gccgcggccg ctgcagctgc agcagcggcc gccggcctgg
     1441 gcctcgggcc tggcctaagc cctgcatcca tgatgaggcc ggggcaggtc tccctcctgg
     1501 gtcctgatgc tgtttctgtg ctcggctctg gcttgggcct cagccctggc accagctctg
     1561 gccgcaaccc tgaccctggc tctgggccgg gcactctgcc ggatcccagc tccaaacccc
     1621 tccccggctc cagatccacc cccagcccta ctcctgtgga atcttctgac ccaaaggctg
     1681 ggcacgacgc tggtcccgac cttgtgccca gcccagacct tgatcctgtg cccagcccag
     1741 accctgatcc tgtgcccagc cctgatccca accctgtgtc ctgccctgac ccctgttctc
     1801 ccactcgtgg cactgtcagc ccagccctcc ctaccggcga gagtccagag tgggtacagg
     1861 agcaaggggc actgctgggg cctgatggct gaaggagacg ccggcatcct cgggggcctg
     1921 gggaagttgt gtgttgtgca gtcagtaaaa tcctcccact gcctccgg
//
