LOCUS       NM_058230               2794 bp    mRNA    linear   PRI 05-APR-2024
DEFINITION  Homo sapiens zinc finger protein 354B (ZNF354B), mRNA.
ACCESSION   NM_058230
VERSION     NM_058230.3
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 2794)
  AUTHORS   Gaudet,P., Livstone,M.S., Lewis,S.E. and Thomas,P.D.
  TITLE     Phylogenetic-based propagation of functional annotations within the
            Gene Ontology consortium
  JOURNAL   Brief Bioinform 12 (5), 449-462 (2011)
   PUBMED   21873635
REFERENCE   2  (bases 1 to 2794)
  AUTHORS   Gerhard,D.S., Wagner,L., Feingold,E.A., Shenmen,C.M., Grouse,L.H.,
            Schuler,G., Klein,S.L., Old,S., Rasooly,R., Good,P., Guyer,M.,
            Peck,A.M., Derge,J.G., Lipman,D., Collins,F.S., Jang,W., Sherry,S.,
            Feolo,M., Misquitta,L., Lee,E., Rotmistrovsky,K., Greenhut,S.F.,
            Schaefer,C.F., Buetow,K., Bonner,T.I., Haussler,D., Kent,J.,
            Kiekhaus,M., Furey,T., Brent,M., Prange,C., Schreiber,K.,
            Shapiro,N., Bhat,N.K., Hopkins,R.F., Hsie,F., Driscoll,T.,
            Soares,M.B., Casavant,T.L., Scheetz,T.E., Brown-stein,M.J.,
            Usdin,T.B., Toshiyuki,S., Carninci,P., Piao,Y., Dudekula,D.B.,
            Ko,M.S., Kawakami,K., Suzuki,Y., Sugano,S., Gruber,C.E.,
            Smith,M.R., Simmons,B., Moore,T., Waterman,R., Johnson,S.L.,
            Ruan,Y., Wei,C.L., Mathavan,S., Gunaratne,P.H., Wu,J., Garcia,A.M.,
            Hulyk,S.W., Fuh,E., Yuan,Y., Sneed,A., Kowis,C., Hodgson,A.,
            Muzny,D.M., McPherson,J., Gibbs,R.A., Fahey,J., Helton,E.,
            Ketteman,M., Madan,A., Rodrigues,S., Sanchez,A., Whiting,M.,
            Madari,A., Young,A.C., Wetherby,K.D., Granite,S.J., Kwong,P.N.,
            Brinkley,C.P., Pearson,R.L., Bouffard,G.G., Blakesly,R.W.,
            Green,E.D., Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J.,
            Myers,R.M., Butterfield,Y.S., Griffith,M., Griffith,O.L.,
            Krzywinski,M.I., Liao,N., Morin,R., Palmquist,D., Petrescu,A.S.,
            Skalska,U., Smailus,D.E., Stott,J.M., Schnerch,A., Schein,J.E.,
            Jones,S.J., Holt,R.A., Baross,A., Marra,M.A., Clifton,S.,
            Makowski,K.A., Bosak,S. and Malek,J.
  CONSRTM   MGC Project Team
  TITLE     The status, quality, and expansion of the NIH full-length cDNA
            project: the Mammalian Gene Collection (MGC)
  JOURNAL   Genome Res 14 (10B), 2121-2127 (2004)
   PUBMED   15489334
  REMARK    Erratum:[Genome Res. 2006 Jun;16(6):804. Morrin, Ryan [corrected to
            Morin, Ryan]]
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AI683630.1, BC104777.1, AA599717.1 and AC126915.2.
            
            On May 17, 2019 this sequence version replaced NM_058230.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC036466.1, SRR1803615.253181.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA1965299, SAMEA1966682
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000322434.8/ ENSP00000327143.3
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-169               AI683630.1         1-169
            170-2092            BC104777.1         1-1923
            2093-2197           AA599717.1         4-108               c
            2198-2794           AC126915.2         15367-15963         c
FEATURES             Location/Qualifiers
     source          1..2794
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="5"
                     /map="5q35.3"
     gene            1..2794
                     /gene="ZNF354B"
                     /gene_synonym="KID2"
                     /note="zinc finger protein 354B"
                     /db_xref="GeneID:117608"
                     /db_xref="HGNC:HGNC:17197"
     exon            1..175
                     /gene="ZNF354B"
                     /gene_synonym="KID2"
                     /inference="alignment:Splign:2.1.0"
     exon            176..259
                     /gene="ZNF354B"
                     /gene_synonym="KID2"
                     /inference="alignment:Splign:2.1.0"
     CDS             227..2065
                     /gene="ZNF354B"
                     /gene_synonym="KID2"
                     /codon_start=1
                     /product="zinc finger protein 354B"
                     /protein_id="NP_478137.1"
                     /db_xref="CCDS:CCDS4439.1"
                     /db_xref="GeneID:117608"
                     /db_xref="HGNC:HGNC:17197"
                     /translation="MAAGQREARPQVSLTFEDVAVLFTWDEWRKLAPSQRNLYRDVML
                     ENYRNLVSLGLSFTKPKVISLLQQGEDPWEVEKDSSGVSSLGCKSTPKMTKSTQTQDS
                     FQEQIRKRLKRDEPWNFISERSCIYEEKLKKQQDKNENLQIISVAHTKILTVDRSHKN
                     VEFGQNFYLKSVFIKQQRFAKEKTPSKCEIQRNSFKQNSNLLNQSKIKTAEKRYKCST
                     CEKAFIHNSSLRKHQKNHTGEKLFKCKECLKAFSQSSALIQHQRTHTGEKPYICKECG
                     KAFSHSASLCKHLRTHTVEKCYRCKECGKSFSRRSGLFIHQKIHAQENPHKYNPGRKA
                     SSYSTSLSGSQKIHLRKKSYLCNECGNTFKSSSSLRYHQRIHTGEKPFKCSECGRAFS
                     QSASLIQHERIHTGEKPYRCNECGKGFTSISRLNRHRIIHTGEKLYNCNECGKALSSH
                     STLIIHERIHTGEKPCKCKVCGKAFRQSSALIQHQRMHTGERPYKCNECDKTFRCNSS
                     LSNHQRIHTGEKPYRCLECGMSFGQSAALIQHQRIHTGEKPFKCNTCGKTFRQSSSLI
                     AHQRIHTGEKPYECNACGKLFSQRSSLTNHYKIHIEEDSLKADLHV"
     exon            260..386
                     /gene="ZNF354B"
                     /gene_synonym="KID2"
                     /inference="alignment:Splign:2.1.0"
     exon            387..482
                     /gene="ZNF354B"
                     /gene_synonym="KID2"
                     /inference="alignment:Splign:2.1.0"
     exon            483..2794
                     /gene="ZNF354B"
                     /gene_synonym="KID2"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2118..2123
                     /regulatory_class="polyA_signal_sequence"
                     /gene="ZNF354B"
                     /gene_synonym="KID2"
                     /note="hexamer: AATATA"
     polyA_site      2138
                     /gene="ZNF354B"
                     /gene_synonym="KID2"
     regulatory      2171..2176
                     /regulatory_class="polyA_signal_sequence"
                     /gene="ZNF354B"
                     /gene_synonym="KID2"
                     /note="hexamer: AATAAA"
     polyA_site      2205
                     /gene="ZNF354B"
                     /gene_synonym="KID2"
                     /note="major polyA site"
     regulatory      2779..2784
                     /regulatory_class="polyA_signal_sequence"
                     /gene="ZNF354B"
                     /gene_synonym="KID2"
                     /note="hexamer: ATTAAA"
     polyA_site      2794
                     /gene="ZNF354B"
                     /gene_synonym="KID2"
                     /note="major polyA site"
ORIGIN      
        1 agcggccgcc ttgctcctct aggtcccagg cgctctgcgg agctttcgct gcccggtgag
       61 cggcgccggg cttgaggtcg cccagacgtc ggaggagccg ggtcacgagg ctggagcttc
      121 ctgcttgcag agtgcggcgg ggaggcgcgg cccgggaacg cgggatcctg gggagatctg
      181 ccttctggag actgcgccgt cctcccggga gagccagaaa gaggacatgg ctgctgggca
      241 gcgggaagcg aggccccagg tgtcactgac attcgaggac gtggctgtgc tctttacctg
      301 ggatgagtgg agaaagctgg ctccttctca gagaaacttg taccgggatg tgatgctgga
      361 gaactatagg aacctggtct cactgggact ctcatttacc aaaccaaaag tcatctccct
      421 gttgcagcaa ggagaagatc cctgggaggt ggagaaagac agttctggtg tctcctctct
      481 aggatgtaag agcacaccta aaatgacaaa gtcaactcaa actcaggatt catttcagga
      541 gcagataagg aaaagattga aaagggatga accctggaac ttcatatcag aaagatcctg
      601 catatatgaa gagaaattaa agaaacagca ggacaaaaat gaaaatttac aaataatttc
      661 agttgcccat acaaaaatcc ttactgtaga tagaagccat aaaaatgttg aatttggcca
      721 aaacttctac ctgaaatcag tcttcattaa gcaacagaga tttgctaaag aaaaaactcc
      781 atcaaaatgt gaaatacaaa gaaatagttt caagcagaat tcaaatttac ttaaccaatc
      841 aaaaatcaaa acagcagaga aacgctataa atgcagtaca tgtgaaaaag ccttcattca
      901 caattcatcc cttcgtaaac atcagaaaaa ccacactgga gaaaaattat ttaaatgtaa
      961 agaatgttta aaagctttca gccaaagttc tgctcttatt caacatcaaa gaactcatac
     1021 aggagagaaa ccctatatat gtaaagaatg tgggaaagcc ttcagccata gtgcatccct
     1081 ttgtaagcat ttaaggaccc atactgtgga gaaatgctat agatgtaaag aatgtggtaa
     1141 atccttcagt cgaaggtctg ggctttttat acatcaaaaa atccatgctc aagaaaatcc
     1201 ccataaatac aatccaggca ggaaggcatc cagttacagc acttcccttt ctggaagtca
     1261 gaaaattcat ctcagaaaga agtcctactt atgtaatgaa tgtggcaaca cctttaagtc
     1321 tagctcatcc cttcgttatc atcagagaat tcacactgga gagaagcctt ttaaatgtag
     1381 tgaatgtggg agagccttca gccagagtgc ctctcttatt caacatgaaa gaattcacac
     1441 cggagaaaag ccctatagat gcaatgaatg tgggaaaggc tttacttcta tttcacgact
     1501 taatagacac cgaataattc atactggaga gaaattgtat aattgtaatg aatgtggtaa
     1561 agccttaagc tcccactcaa cacttattat tcatgagcga attcatactg gagaaaaacc
     1621 atgtaaatgt aaagtatgtg gaaaagcctt cagacagagt tccgctctca ttcaacatca
     1681 gagaatgcat actggagaaa gaccctataa gtgtaacgaa tgtgacaaaa cattcaggtg
     1741 taactcatcg cttagtaatc accagagaat tcatactgga gagaaaccat atcgatgttt
     1801 agaatgtggg atgtcttttg gccaaagtgc agctcttata caacatcaga ggattcatac
     1861 aggagaaaaa ccctttaaat gtaatacatg tggaaaaact tttagacaaa gctcatcact
     1921 tattgcacat caaagaattc atactggaga gaaaccctat gaatgtaatg catgtgggaa
     1981 actctttagc cagaggtcat cccttactaa tcattataaa attcacattg aagaggactc
     2041 cttaaaagcc gatttgcatg tgtgaaagcc ttaaaccaaa actcatcaga gaatacatgc
     2101 ttgagagtga tttattaaat ataatgaata tgagaaaact cttagttctc atcagatact
     2161 aagttttaag aataaacttt agctatgtaa taacttatgg gaaaagcttt tatacttgtc
     2221 actcactttt taaaatatcc cgagacagtt cactgttgca gacattgaaa ttggccattt
     2281 gtaagataaa aggtatgttt ataaaatctc tttatataat atatgctatc tatgacatgc
     2341 aaaaaagaaa agtctgggtg ctgaggtgct gaatttttca ttagaaaaac atttgtataa
     2401 actactatta tataaatata agcatattta ttacagcaaa cattttaata gcaaacaaaa
     2461 caattgatct taaaaatata tgcaatatat acttacctgg cagggaagat taccatgatc
     2521 acgaaggtgg ttttcccagg gcaaggctta tccattgcac tccagatgtg ctgacccctt
     2581 caatttccca aaatgtggaa aactcaactg cataatttat ggtagtgggg gactacattc
     2641 gcactttctc ctgaaatata tatatatatg cagtattaga gcaaaggacc aataagagat
     2701 aaaaactaac tgaactacct cttagtgcct ggaatttacc ttttcctgac ttactgtcaa
     2761 acttcgtgca tggcttttat taaaaaagaa aaaa
//
