LOCUS       NM_003420               2658 bp    mRNA    linear   PRI 19-SEP-2024
DEFINITION  Homo sapiens zinc finger protein 35 (ZNF35), mRNA.
ACCESSION   NM_003420
VERSION     NM_003420.4
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 2658)
  AUTHORS   Huttlin,E.L., Bruckner,R.J., Navarrete-Perea,J., Cannon,J.R.,
            Baltier,K., Gebreab,F., Gygi,M.P., Thornock,A., Zarraga,G., Tam,S.,
            Szpyt,J., Gassaway,B.M., Panov,A., Parzen,H., Fu,S., Golbazi,A.,
            Maenpaa,E., Stricker,K., Guha Thakurta,S., Zhang,T., Rad,R.,
            Pan,J., Nusinow,D.P., Paulo,J.A., Schweppe,D.K., Vaites,L.P.,
            Harper,J.W. and Gygi,S.P.
  TITLE     Dual proteome-scale networks reveal cell-specific remodeling of the
            human interactome
  JOURNAL   Cell 184 (11), 3022-3040 (2021)
   PUBMED   33961781
REFERENCE   2  (bases 1 to 2658)
  AUTHORS   Luck,K., Kim,D.K., Lambourne,L., Spirohn,K., Begg,B.E., Bian,W.,
            Brignall,R., Cafarelli,T., Campos-Laborie,F.J., Charloteaux,B.,
            Choi,D., Cote,A.G., Daley,M., Deimling,S., Desbuleux,A., Dricot,A.,
            Gebbia,M., Hardy,M.F., Kishore,N., Knapp,J.J., Kovacs,I.A.,
            Lemmens,I., Mee,M.W., Mellor,J.C., Pollis,C., Pons,C.,
            Richardson,A.D., Schlabach,S., Teeking,B., Yadav,A., Babor,M.,
            Balcha,D., Basha,O., Bowman-Colin,C., Chin,S.F., Choi,S.G.,
            Colabella,C., Coppin,G., D'Amata,C., De Ridder,D., De Rouck,S.,
            Duran-Frigola,M., Ennajdaoui,H., Goebels,F., Goehring,L., Gopal,A.,
            Haddad,G., Hatchi,E., Helmy,M., Jacob,Y., Kassa,Y., Landini,S.,
            Li,R., van Lieshout,N., MacWilliams,A., Markey,D., Paulson,J.N.,
            Rangarajan,S., Rasla,J., Rayhan,A., Rolland,T., San-Miguel,A.,
            Shen,Y., Sheykhkarimli,D., Sheynkman,G.M., Simonovsky,E., Tasan,M.,
            Tejeda,A., Tropepe,V., Twizere,J.C., Wang,Y., Weatheritt,R.J.,
            Weile,J., Xia,Y., Yang,X., Yeger-Lotem,E., Zhong,Q., Aloy,P.,
            Bader,G.D., De Las Rivas,J., Gaudet,S., Hao,T., Rak,J.,
            Tavernier,J., Hill,D.E., Vidal,M., Roth,F.P. and Calderwood,M.A.
  TITLE     A reference map of the human binary protein interactome
  JOURNAL   Nature 580 (7803), 402-408 (2020)
   PUBMED   32296183
REFERENCE   3  (bases 1 to 2658)
  AUTHORS   Huttlin,E.L., Bruckner,R.J., Paulo,J.A., Cannon,J.R., Ting,L.,
            Baltier,K., Colby,G., Gebreab,F., Gygi,M.P., Parzen,H., Szpyt,J.,
            Tam,S., Zarraga,G., Pontano-Vaites,L., Swarup,S., White,A.E.,
            Schweppe,D.K., Rad,R., Erickson,B.K., Obar,R.A., Guruharsha,K.G.,
            Li,K., Artavanis-Tsakonas,S., Gygi,S.P. and Harper,J.W.
  TITLE     Architecture of the human interactome defines protein communities
            and disease networks
  JOURNAL   Nature 545 (7655), 505-509 (2017)
   PUBMED   28514442
REFERENCE   4  (bases 1 to 2658)
  AUTHORS   Zhou,H., Liu,L.H., Zhang,H., Lei,Z. and Lan,Z.J.
  TITLE     Expression of zinc finger protein 105 in the testis and its role in
            male fertility
  JOURNAL   Mol Reprod Dev 77 (6), 511-520 (2010)
   PUBMED   20186958
REFERENCE   5  (bases 1 to 2658)
  AUTHORS   Vaquerizas,J.M., Kummerfeld,S.K., Teichmann,S.A. and Luscombe,N.M.
  TITLE     A census of human transcription factors: function, expression and
            evolution
  JOURNAL   Nat Rev Genet 10 (4), 252-263 (2009)
   PUBMED   19274049
  REMARK    Review article
REFERENCE   6  (bases 1 to 2658)
  AUTHORS   Calabro,V., Pengue,G., Bartoli,P.C., Pagliuca,A., Featherstone,T.
            and Lania,L.
  TITLE     Positional cloning of cDNAs from the human chromosome 3p21-22
            region identifies a clustered organization of zinc-finger genes
  JOURNAL   Hum Genet 95 (1), 18-21 (1995)
   PUBMED   7814019
REFERENCE   7  (bases 1 to 2658)
  AUTHORS   Pengue,G., Cannada-Bartoli,P. and Lania,L.
  TITLE     The ZNF35 human zinc finger gene encodes a sequence-specific
            DNA-binding protein
  JOURNAL   FEBS Lett 321 (2-3), 233-236 (1993)
   PUBMED   8477855
REFERENCE   8  (bases 1 to 2658)
  AUTHORS   Lanfrancone,L., Pengue,G., Pandolfi,P.P., Salcini,A.E.,
            Giacomucci,A., Longo,L., Donti,E., De Luca,P., La Mantia,G.,
            Pelicci,P.G. et al.
  TITLE     Structural and functional organization of the HF.10 human zinc
            finger gene (ZNF35) located on chromosome 3p21-p22
  JOURNAL   Genomics 12 (4), 720-728 (1992)
   PUBMED   1572646
REFERENCE   9  (bases 1 to 2658)
  AUTHORS   Donti,E., Lanfrancone,L., Huebner,K., Pascucci,A., Venti,G.,
            Pengue,G., Grignani,F., Croce,C.M., Lania,L. and Pelicci,P.G.
  TITLE     Localization of the human HF.10 finger gene on a chromosome region
            (3p21-22) frequently deleted in human cancers
  JOURNAL   Hum Genet 84 (5), 391-395 (1990)
   PUBMED   2108922
REFERENCE   10 (bases 1 to 2658)
  AUTHORS   Pannuti,A., Lanfrancone,L., Pascucci,A., Pelicci,P.G., La Mantia,G.
            and Lania,L.
  TITLE     Isolation of cDNAs encoding finger proteins and measurement of the
            corresponding mRNA levels during myeloid terminal differentiation
  JOURNAL   Nucleic Acids Res 16 (10), 4227-4237 (1988)
   PUBMED   3380682
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC099669.2, BP237260.1, BC013597.1 and BC015892.1.
            
            On Nov 23, 2018 this sequence version replaced NM_003420.3.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR1803613.210570.1,
                                           SRR1803611.117490.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA1965299, SAMEA1966682
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000396056.7/ ENSP00000379368.2
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-9                 AC099669.2         205431-205439
            10-31               BP237260.1         1-22
            32-2651             BC013597.1         1-2620
            2652-2658           BC015892.1         2475-2481
FEATURES             Location/Qualifiers
     source          1..2658
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="3"
                     /map="3p21.31"
     gene            1..2658
                     /gene="ZNF35"
                     /gene_synonym="HF.10; HF10; Zfp105"
                     /note="zinc finger protein 35"
                     /db_xref="GeneID:7584"
                     /db_xref="HGNC:HGNC:13099"
                     /db_xref="MIM:194533"
     exon            1..103
                     /gene="ZNF35"
                     /gene_synonym="HF.10; HF10; Zfp105"
                     /inference="alignment:Splign:2.1.0"
     exon            104..422
                     /gene="ZNF35"
                     /gene_synonym="HF.10; HF10; Zfp105"
                     /inference="alignment:Splign:2.1.0"
     CDS             231..1814
                     /gene="ZNF35"
                     /gene_synonym="HF.10; HF10; Zfp105"
                     /note="zinc finger protein 35 (clone HF.10); zinc finger
                     protein HF.10"
                     /codon_start=1
                     /product="zinc finger protein 35"
                     /protein_id="NP_003411.3"
                     /db_xref="CCDS:CCDS2718.2"
                     /db_xref="GeneID:7584"
                     /db_xref="HGNC:HGNC:13099"
                     /db_xref="MIM:194533"
                     /translation="MTAELREAMALAPWGPVKVKKEEEEEENFPGQASSQQVHSENIK
                     VWAPVQGLQTGLDGSEEEEKGQNISWDMAVVLKATQEAPAASTLGSYSLPGTLAKSEI
                     LETHGTMNFLGAETKNLQLLVPKTEICEEAEKPLIISERIQKADPQGPELGEACEKGN
                     MLKRQRIKREKKDFRQVIVNDCHLPESFKEEENQKCKKSGGKYSLNSGAVKNPKTQLG
                     QKPFTCSVCGKGFSQSANLVVHQRIHTGEKPFECHECGKAFIQSANLVVHQRIHTGQK
                     PYVCSKCGKAFTQSSNLTVHQKIHSLEKTFKCNECEKAFSYSSQLARHQKVHITEKCY
                     ECNECGKTFTRSSNLIVHQRIHTGEKPFACNDCGKAFTQSANLIVHQRSHTGEKPYEC
                     KECGKAFSCFSHLIVHQRIHTAEKPYDCSECGKAFSQLSCLIVHQRIHSGDLPYVCNE
                     CGKAFTCSSYLLIHQRIHNGEKPYTCNECGKAFRQRSSLTVHQRTHTGEKPYECEKCG
                     AAFISNSHLMRHHRTHLVE"
     exon            423..567
                     /gene="ZNF35"
                     /gene_synonym="HF.10; HF10; Zfp105"
                     /inference="alignment:Splign:2.1.0"
     exon            568..2658
                     /gene="ZNF35"
                     /gene_synonym="HF.10; HF10; Zfp105"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2631..2636
                     /regulatory_class="polyA_signal_sequence"
                     /gene="ZNF35"
                     /gene_synonym="HF.10; HF10; Zfp105"
                     /note="hexamer: AATAAA"
     polyA_site      2658
                     /gene="ZNF35"
                     /gene_synonym="HF.10; HF10; Zfp105"
                     /note="major polyA site"
ORIGIN      
        1 ctgtccggtc attgttctcg tgccggtaga agctgaagta ccggtcagcc agcctcctgc
       61 tgcagagcca gtgaactcag gtcgggcttc tcagctgcgc acataggcag tactcatctt
      121 ggccctggga agaaactcaa gaagaagctt ttgaaacata aagcttggat ggggtttgac
      181 ctctgcaggg cagcgcccag ctataggagt tcccctgctg agcagagaag atgactgcag
      241 aattgagaga agccatggcc ctagccccat ggggcccagt gaaggtgaaa aaggaggagg
      301 aagaagaaga aaacttccca ggtcaggcat ccagccaaca agtgcactcc gagaacatca
      361 aagtctgggc cccagtgcag ggtcttcaga caggccttga tggatcagaa gaggaagaaa
      421 agggtcagaa catatcctgg gatatggcgg tagtcctgaa agcaactcag gaggcacctg
      481 ctgcttcaac ccttggcagc tactcattac cagggactct ggccaagagt gagatactgg
      541 agactcatgg gaccatgaac tttctaggtg ctgaaaccaa gaacctacag ttactggttc
      601 caaaaactga gatatgtgag gaagctgaaa aacccctcat catatcagaa agaatccaga
      661 aagctgatcc tcaaggacct gagttaggag aagcttgtga aaagggaaac atgttaaaga
      721 ggcagagaat aaagagagaa aagaaagatt tcagacaagt gatagtgaat gactgtcact
      781 tacctgaaag cttcaaagaa gaggaaaacc agaaatgtaa gaaatctgga ggaaaatata
      841 gccttaattc tggcgctgtt aaaaatccaa aaacccagct tggacaaaag ccttttacgt
      901 gtagcgtgtg tgggaaagga tttagtcaga gtgcaaacct cgttgtgcat cagcgaatcc
      961 acactggaga gaaacccttt gaatgtcatg agtgtgggaa ggccttcatt cagagtgcaa
     1021 acctcgttgt gcatcagaga atccacactg gacagaaacc ttatgtttgc tcaaaatgtg
     1081 ggaaagcctt cactcagagt tcaaatctga ctgtacatca aaaaatccac tccttagaaa
     1141 aaacttttaa gtgcaatgaa tgtgagaaag cctttagtta cagctcacaa cttgctcggc
     1201 accagaaagt ccacattacg gaaaaatgct atgaatgtaa tgaatgtggg aaaacattta
     1261 ctaggagctc aaacctcatt gtccaccaga ggatccacac tggggagaag ccctttgcct
     1321 gtaacgactg tggcaaagcc tttacccaga gtgcaaatct tattgtacat cagcgaagcc
     1381 atactggtga gaagccatat gagtgtaaag agtgtgggaa agcctttagt tgtttttcac
     1441 accttattgt gcaccagaga attcacactg cagagaaacc ttacgactgc agcgaatgtg
     1501 ggaaagcctt cagtcagctc tcttgcctta ttgtccacca gagaattcac agtggagatc
     1561 ttccttacgt gtgtaatgaa tgtgggaagg ccttcacatg tagctcatac ctacttattc
     1621 atcagagaat tcataatgga gaaaaacctt acacatgtaa tgagtgtggg aaggccttca
     1681 gacagaggtc gagcctcacc gtgcaccaga gaacccacac tggggagaag ccctatgaat
     1741 gtgagaagtg tggtgcagct ttcatttcca actcacacct catgcgacac catagaaccc
     1801 atcttgttga ataacaagta aggaagagga agacctccag cattggtcat aaccttctgc
     1861 ctccctaatg agacacctct ttgctgtttt cttcctcctc tataaaagtg agggctgtgt
     1921 ccttaaaagt tatagttttc aggaatgcag cagaagacac aagaaaagca tttcagaggc
     1981 taatttaaaa caaaaagtaa gcacctaaag gcaaggactt tgttttaact gtaccttaag
     2041 cggtcatgtt ctctgaagtg gaatgtggct ttcctaggaa tgggtcgtac aaagctaagt
     2101 ggtaatgatg ctatttgggg aaaggtcttt tttgcttaat tttgtttttt aaaactctga
     2161 tgattgcttg agcaacaggc aggttatctg cctggttgaa ttctggttga accgtgtatt
     2221 ctaatatttc tggttaagtg gtgactgggt aaggaaacca cttggggtag cagttcaaca
     2281 attcacttac gaatgtttat aagctttcca tttcctaggt aattttttaa aagccagtca
     2341 aaacaaaaac tttactgaaa atggacagaa ataggaaatg gactttttcc ttactgtcta
     2401 tacctcctga accttggtat tgtaaagatc tggggacctc tgggtctgtt ctgaccattc
     2461 cctagtctcc atggccaagc actcaaggat tgatggacac cacacaccag ctatattcat
     2521 ttgccaagat caacagctcc ttctccaaac aactcaagcc cccaattccc atcgcattcc
     2581 atttgggtga gatgcaacta acagcccctt cctggatgaa ggagtcaaag aataaagctt
     2641 gcctagaggc atgcccca
//
