LOCUS       NM_032584               7984 bp    mRNA    linear   PRI 07-APR-2024
DEFINITION  Homo sapiens zinc finger protein 347 (ZNF347), transcript variant
            3, mRNA.
ACCESSION   NM_032584
VERSION     NM_032584.3
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 7984)
  AUTHORS   Gaudet,P., Livstone,M.S., Lewis,S.E. and Thomas,P.D.
  TITLE     Phylogenetic-based propagation of functional annotations within the
            Gene Ontology consortium
  JOURNAL   Brief Bioinform 12 (5), 449-462 (2011)
   PUBMED   21873635
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            DB214217.1, AY029765.1, AC010328.4, AA776564.1, DB316074.1,
            AI366675.1 and AA978292.1.
            
            On Jun 2, 2019 this sequence version replaced NM_032584.2.
            
            Transcript Variant: This variant (3) differs in the 5' UTR and uses
            an alternate in-frame splice site in the coding region, compared to
            variant 1. The resulting isoform (b) lacks one internal amino acid,
            compared to isoform a.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK314603.1, SRR1803611.117482.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN03267750, SAMN03267754
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000334197.12/ ENSP00000334146.6
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-37                DB214217.1         17-53
            38-880              AY029765.1         16-858
            881-881             AC010328.4         4163-4163
            882-3524            AY029765.1         860-3502
            3525-3681           AA776564.1         1-157               c
            3682-4027           DB316074.1         92-437              c
            4028-4214           AI366675.1         1-187               c
            4215-4215           AA978292.1         12-12               c
            4216-7984           AC010328.4         7498-11266
FEATURES             Location/Qualifiers
     source          1..7984
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="19"
                     /map="19q13.42"
     gene            1..7984
                     /gene="ZNF347"
                     /gene_synonym="ZNF1111"
                     /note="zinc finger protein 347"
                     /db_xref="GeneID:84671"
                     /db_xref="HGNC:HGNC:16447"
     exon            1..45
                     /gene="ZNF347"
                     /gene_synonym="ZNF1111"
                     /inference="alignment:Splign:2.1.0"
     exon            46..106
                     /gene="ZNF347"
                     /gene_synonym="ZNF1111"
                     /inference="alignment:Splign:2.1.0"
     CDS             92..2611
                     /gene="ZNF347"
                     /gene_synonym="ZNF1111"
                     /note="isoform b is encoded by transcript variant 3; zinc
                     finger 1111; zinc finger protein 1111; CTD-2620I22.7"
                     /codon_start=1
                     /product="zinc finger protein 347 isoform b"
                     /protein_id="NP_115973.2"
                     /db_xref="CCDS:CCDS33097.1"
                     /db_xref="GeneID:84671"
                     /db_xref="HGNC:HGNC:16447"
                     /translation="MALTQGQVTFRDVAIEFSQEEWTCLDPAQRTLYRDVMLENYRNL
                     ASLGISCFDLSIISMLEQGKEPFTLESQVQIAGNPDGWEWIKAVITALSSEFVMKDLL
                     HKGKSNTGEVFQTVMLERQESQDIEGCSFREVQKNTHGLEYQCRDAEGNYKGVLLTQE
                     GNLTHGRDEHDKRDARNKLIKNQLGLSLQSHLPELQLFQYEGKIYECNQVEKSFNNNS
                     SVSPPQQMPYNVKTHISKKYLKDFISSLLLTQGQKANNWGSPYKSNGCGMVFPQNSHL
                     ASHQRSHTKEKPYKCYECGKAFRTRSNLTTHQVIHTGEKRYKCNECGKVFSRNSQLSQ
                     HQKIHTGEKPYKCNECGKVFTQNSHLVRHRGIHTGEKPYKCNECGKAFRARSSLAIHQ
                     ATHSGEKPYKCNECGKVFTQNSHLTNHWRIHTGEKPYKCNECGKAFGVRSSLAIHLVI
                     HTGEKPYKCHECGKVFRRNSHLARHQLIHTGEKPYKCNECGKAFRAHSNLTTHQVIHT
                     GEKPYKCNECGKVFTQNSHLANHQRIHTGVKPYMCNECGKAFSVYSSLTTHQVIHTGE
                     KPYKCNECGKVFTQNSHLARHRGIHTGEKPYKCNECGKVFRHNSYLSRHQRIHTGEKP
                     YKYNEYGKAFSEHSNLTTHQVIHTGEKPYKCNECGKVFTQNSHLARHRRVHTGGKPYQ
                     CNECGKAFSQTSKLARHQRVHTGEKPYECNQCGKAFSVRSSLTTHQAIHTGKKPYKCN
                     ECGKVFTQNSHLARHRGIHTGEKPYKCNECGKAFSQTSKLARHQRIHTGEKPYECGKP
                     FSICSSLTTHQTIHTGGKPYKCNVWKVLKSEFKPCKPSQNS"
     exon            107..233
                     /gene="ZNF347"
                     /gene_synonym="ZNF1111"
                     /inference="alignment:Splign:2.1.0"
     exon            234..362
                     /gene="ZNF347"
                     /gene_synonym="ZNF1111"
                     /inference="alignment:Splign:2.1.0"
     exon            363..7984
                     /gene="ZNF347"
                     /gene_synonym="ZNF1111"
                     /inference="alignment:Splign:2.1.0"
     regulatory      7959..7964
                     /regulatory_class="polyA_signal_sequence"
                     /gene="ZNF347"
                     /gene_synonym="ZNF1111"
                     /note="hexamer: ATTAAA"
     polyA_site      7984
                     /gene="ZNF347"
                     /gene_synonym="ZNF1111"
                     /note="major polyA site"
ORIGIN      
        1 agttccggaa gcggatcgtg ttgggtgcgg gtgacgccgc cgagcgaaga acccttgaag
       61 aagaggaaga ggaaagaaag acaagtcagg catggctctc acccagggac aggtgacatt
      121 cagggatgtg gctatagaat tctctcagga ggagtggaca tgcctggacc ccgctcagag
      181 gactttgtac agggacgtga tgttggagaa ttataggaac ctggcctccc tgggaatctc
      241 ttgttttgac ctcagtatta tctctatgtt ggagcaaggg aaggagcctt tcactttgga
      301 gagccaagta caaatagcag gaaacccaga tggatgggaa tggatcaaag ctgtgatcac
      361 agctctctct tccgaatttg taatgaaaga tttactacac aaagggaaga gtaatacagg
      421 agaagtattc caaacagtga tgttggaaag acaggaaagc caagacattg aaggatgttc
      481 cttcagggaa gtccagaaaa atacacatgg ccttgagtat caatgcagag atgctgaagg
      541 aaattacaaa ggagtgcttt tgacccaaga aggcaatctc actcatggaa gagatgaaca
      601 tgataaaaga gatgcaagaa acaagcttat taaaaatcag cttggattaa gccttcagtc
      661 acatctgcct gaactgcagc tttttcaata tgaagggaaa atttatgaat gtaatcaggt
      721 tgagaagtct ttcaacaata attcctcagt ttcaccacct caacaaatgc cttataatgt
      781 caaaacccac atttctaaga aatatctcaa agattttatc tcttctttat tactcacaca
      841 ggggcaaaaa gcaaataatt ggggaagccc ttacaaatct aatggatgtg gcatggtctt
      901 tcctcaaaat tcacaccttg caagtcatca gagaagtcat actaaagaga aaccttacaa
      961 atgttatgag tgtggcaaag cctttagaac acgttcaaac ctaactaccc atcaggtgat
     1021 ccatactggc gaaaaacgtt acaaatgtaa tgagtgtggt aaggtcttta gtcgaaattc
     1081 acaactctca caacatcaga aaattcacac tggagagaaa ccttataaat gtaacgaatg
     1141 tggcaaggtc ttcactcaga attcacacct tgtaagacat cgaggaattc atactggaga
     1201 gaaaccttac aagtgtaatg agtgtgggaa agcctttaga gctcgttcaa gcttagctat
     1261 ccatcaggca acccacagtg gagaaaaacc ttacaaatgt aatgaatgtg gcaaggtctt
     1321 cactcaaaat tcacacctta caaatcactg gagaattcac actggagaga aaccttacaa
     1381 gtgtaatgag tgcggcaaag cctttggtgt tcgttcaagc ctagctattc atctggtaat
     1441 tcacaccgga gaaaagcctt acaaatgtca tgaatgcggc aaggtcttta ggcgtaattc
     1501 acaccttgca aggcatcagc taattcatac tggagagaaa ccttataagt gtaatgagtg
     1561 tggcaaagcc tttagagcac attcaaacct aactacccat caggtcatcc atactggaga
     1621 aaagccttac aaatgtaatg aatgtggcaa ggtcttcact caaaattcac accttgcaaa
     1681 tcatcaaaga attcatactg gagtgaagcc ttatatgtgt aatgagtgcg gcaaagcctt
     1741 cagtgtgtat tcaagcctaa ctacccatca ggtcatccat actggagaaa aaccttacaa
     1801 atgtaatgag tgtggcaagg tcttcactca gaattcacac cttgcaagac atcggggaat
     1861 tcatactgga gagaaacctt ataaatgtaa tgaatgtggc aaggtcttta ggcataattc
     1921 atacctttca aggcatcagc gaattcatac tggagagaaa ccttacaagt ataatgagta
     1981 tggcaaagcc tttagtgaac attcaaacct aactacccat caggtcatcc atactggtga
     2041 aaaaccttac aaatgtaatg agtgtggcaa ggtcttcact cagaattcac accttgcaag
     2101 acatcggaga gttcatactg gaggtaaacc ttaccagtgt aatgaatgtg gcaaagcctt
     2161 tagtcaaaca tcaaagcttg caaggcatca gagagttcat actggagaga aaccatatga
     2221 gtgtaatcag tgtgggaaag cctttagtgt ccgttcaagc ctaactaccc atcaggcaat
     2281 ccatactgga aaaaaacctt acaaatgcaa tgagtgtggg aaggtcttca ctcagaattc
     2341 acaccttgca agacatcggg gaattcatac tggagagaaa ccttacaagt gtaatgagtg
     2401 tggcaaagcc tttagtcaaa cttcaaaact tgcaaggcat cagagaattc ataccggaga
     2461 gaaaccatat gagtgtggga aaccctttag tatctgttca agcctaacta cccatcagac
     2521 aatccatact ggtgggaaac cttacaaatg taacgtgtgg aaagttctaa agtcagagtt
     2581 caaaccttgc aagccatcac agaattcata gtggagagaa accttacaaa tgaaggtggt
     2641 aacttttgca gttagaattc attcctttga caacgtcaga gaatttatgc ctgagagatt
     2701 ccttgaaaat gcaatgactg gctgggtgca gtggctcatg cctgtaatcc caacactttg
     2761 ggagtccgag gcaggtggat cacctgaggt caggagttca agaccagcct gaccaacatg
     2821 gcgaaacccc atttctacta aaagtacaca attagctagg cctggtggcg tgcgcctgta
     2881 atcccagcta tataggaggc tgaggcagga gaatcacttg aacccaggag gcggaggttg
     2941 cagtgagcca agatcgtgcc aatgcactcc atcctgggca aaaagagcaa aactccatct
     3001 taaaggaaaa aaaaaaaatg caatgactgt ggcaaactcc tcatgagttc aagtattaat
     3061 agacatccaa gagtccataa taatgagaaa tcacataaat gtactgtgtg tgacagaggc
     3121 tttattcagg cctcacagct ttgcaggcat taaaatctac gtatttgatg gaaccacaca
     3181 aatgtaatgt gtaagagcat cctgaagctc ttactctaag actgtaactg taggtgagga
     3241 ttcatacaaa gagtgactca gtctctagtt ctttgattca cttttaaaat gataaactgc
     3301 acaataatta cacgttccaa tatggtaaaa cttaagacat tatatatttc aaaggtcaaa
     3361 ggacatttgg aaatggctac ttaccttcag gttataaaat cttttattcc attgtttgag
     3421 gtttctcaaa aaggctactg tttgtgactt tcaacctgaa ctatggatct gtggctattt
     3481 tgcatcctta agcacctttc gtggtgccta tctgggaaag aaccacagta tggaaaggct
     3541 tacttcatta catgaggatc atttttatcc atgtttattg aagaaggagg actctgcctt
     3601 gtaaaattaa atattctctc aattgagaga ccatggtttt ggggcagaaa ataatgtaaa
     3661 actatgatat caatcatcat actgattgtg ttcagggtgc ttttctgaga gaaagacacc
     3721 atgggtttta gggaagtaag gctctacctg cattgagcag gccaagacct caggacactg
     3781 gaatttttat gagaggagag taataagtta ttagtgactg attatgtgat gggaatagtg
     3841 caggggaaat ggttgccact ttctctactg aatggcaata gctgttttat agcagagatt
     3901 gatgaaaaat aggcttattt ttgaaattga agaggtaaca gttattagag tggagagctt
     3961 ggtcagaaaa accagaatac catggttttt tttgttttgt tttgttttta gtagaattca
     4021 cactaattgc tggaattaca ttttgctaca gttttattaa gaatgtgtca cagacataat
     4081 gttttgctaa aaaaaattca acgttttctt ataactataa acaaatcaca ttctttgtac
     4141 caacatcatt ttatcctacc tcagtaggat acttcatagc agataataac aatacactca
     4201 gtcttttagg ttggaggatg tagaacaatt ttttttttct ttgtggaatc aacatacaat
     4261 tttgggaaaa tgtaatcata ctctgcactt gaattattct ctctacactc tgccttagaa
     4321 tatttatatg gatataatga aaatcccata gaaagtgcag ttttcatact cttacactct
     4381 gaaagctgcc acagtgttgg tgaatatata ccatattata tttttacatg cttgtgtgct
     4441 aaataactat ggcatgcatc tttatttaca tgaagtgaaa atacaaatat agaaagtgta
     4501 tgggctgggt gtggtggttc atgcctgtaa tcctagcact ttgagagccc aaggcagggg
     4561 ggtcacttga gtccaggagt ttgaaccagc caggacaaca tggcaaaacc ctgtctctac
     4621 aaaaaaaata gaaatattac ccaggcaggg tggctcatgc ctgtagtccc agctcctcag
     4681 ggagactgag gcaggtggat cacttgagcc tggaggcaga ggttgcagtg agccaagatc
     4741 gcgccattgc actccagcct gggtgacaga gcgagaccct gtctcaaaaa aaacaattgt
     4801 atgaaaaata ttggctgggt gtggtggctc acacctgtaa tcccagcact tagggaggcc
     4861 aaggcgggtg gatcatgggg tcagaaaatc gagaccaccc tggccaacac agtgaaaccc
     4921 catctctact aaaaaatacc aaatatatat atattggttg gatgtggtgg catgcgcctg
     4981 taatcccagc tactcgggag gctgaggcag gagaatcact tgaacccagg aggtggaggt
     5041 tgcagtgagc cgagattgcc actgcactcc agcctgggcg agaaagtgag actccgtctc
     5101 aaaaaaaaaa attatgaaat tataaatagt gcagaataac aaaaataaca ctaagaatgc
     5161 tatgctcaca taatttgaca agactaatat tcatgagttt cctcttaaaa atgaacatat
     5221 ataatggaaa ttttgttttt gtaggtaaac tagaagtttc ataaatttag ccttatcatg
     5281 tttttggtaa tgttaatttg tcacctctcc acaggaagtg tattgaactc catttacagt
     5341 ttggtttaga tatggaaaat gaggatgctg aacaatgaag ttttagggaa atgtgtattg
     5401 cataatgagg ctttctgtga gaagcaggat tgacttccca aactggtcca aaatggcttg
     5461 agagagcagg gataaataac ttgcttgggg tgttatggta ataaccttta ataaaagggt
     5521 gggttggggt gaggatccca cacgtgattt gaacttccat ctagtgccaa aggagggaac
     5581 acggacatta tcagcttggc cagatgggca gaataagaag agggagtgca gaggtataaa
     5641 tggtggtata agacaaaaat cacaaaatgg aaactgactg tagtacaaca ctgaatattt
     5701 actcttgcaa cttctgattt ctggccaggc atggccagaa attacaggct catgcctgta
     5761 atcccagcac tttgggagcc cgaggcaggt ggatcacctt aggtcaggag ctcaagacga
     5821 gcctggccaa catggtgaaa ccccatctct actaaaaata caaaaattag ccaggtgtgg
     5881 tggcgcactc ctgtagtcct agctaccagg gaggctgagg caggagaatc acttgaaccc
     5941 gggagacgga ggttgcagtg agctgagatc tcaccactgc actccagcct gggcaataga
     6001 gtgagactct caaaaaaaca aaagaaattt ctaacttctt tgttagggaa gacctccgct
     6061 ttcttcataa tagtagataa tactcttcct ttctgctgaa cccatagggc ccattacaca
     6121 acgtcattct tgaaaatatt tgtgaaatgc tgtttaaatt gcctaaaata tttttacagt
     6181 agttcaatgc aaatgaattt gtggaaaagt ttattacata atatgatcaa gcaattttag
     6241 ccaaagggca tttttccaaa ggctgtgtta tattcatgtc ttgttcagtt tatggtattg
     6301 tgtaacatat tctccatagc ttcttttctt tttttttttc tttttctttt tagacgtggg
     6361 gtctcgctat gttggccagg ttggtcttga actcttggcc tcaagcattc ctcctgcctc
     6421 agcttcccaa agtgctagga ttacagccat gagccaatag tagtaaaatg actttttgtt
     6481 tttgtatatg atttttactt taaggatttt ttccttccat acattttaat ccaaattata
     6541 tgtttactgc atttcttctc tgtgttactc cagtgaacac ttagaaaata cataaatgag
     6601 ggtgttgttt agaaataaaa ttttgtgaca tgaaaatgta tgtaaaacaa tggcaggtac
     6661 agactaggtt ctctgtaaat aggaaaatgg agtgtccttg taaatcttta gttcaattaa
     6721 agtacaggga tactagatgg tgaaatgaag tctcttaata tggaagttat caaagatcag
     6781 atgcttgaaa atcaagcgtg tggaggttaa ccagcatctg gagaagtaaa tgaaaataca
     6841 gttaataaga gagtccccaa gatattaatt atcatttatg caaaggagat aatttctctc
     6901 attgaatccc tggaggcaat tcaacttcct actgtggctg gtatttcttt tctgagccag
     6961 aggatcttac agcaaaacat gatatttgtg caacttttgc aatgacagct gccatttaat
     7021 atactcccct tagatttgtt tccattttaa aaaactgata tatattcttt aataagtgat
     7081 ttatctttgc atatatattt tatatcaatc acatttagag taagaatcac agttattaat
     7141 gctttatgtg taacaactga atcatcagct cctgaaataa gtattaatga tattctcatt
     7201 tcagaggtga ggaaacttag gacagataag caaaataatc aaattaggct gggcacagtg
     7261 gctcatgcct gtaatcccag cactttggga ggccgaggcg gggggatcac ctgaggtcag
     7321 gaattcgaga ccagcctgat caacatggtg aaaccccgtc tctactaaaa atacaaaaat
     7381 tagctgggtg tgatggcggg cgcctgtaat cccagctatt cgggaggctg aggcaggaga
     7441 attgcttgag cctgggaggc ggatgttgca gttagccgag ttcccaccat tgcactccag
     7501 tctcagtgac agagcgggac tccatctctc tctctctctc tctctctctt tctctctctc
     7561 tctctctctc tctctctcta tatatatata tatatatata tatatatata tatatatatt
     7621 tagaaaatgg gtagaactat gaagagacat ttcactgaag cagttatact gagataaata
     7681 ggcacataaa aagatttcca acatcaccat ccatcaaatc tcagatctca gcatattctg
     7741 ctttaaaaga ctcatcttgt cacatttcag taagaggcag aatcgagatt tgaatccatg
     7801 ttgtctggtt gcaaagacaa agcttttaat gatgatgcta cagtaacaat gctagttatt
     7861 tttgtccttt actcaccatc tatacctatt ttgttagtat ctcttgtaat ttttaaatgg
     7921 tttatcttca tatatcattg tgattgtggt aactttgtat taaatctata tttttataga
     7981 tcaa
//
