LOCUS       NM_015655               4237 bp    mRNA    linear   PRI 04-APR-2024
DEFINITION  Homo sapiens zinc finger protein 337 (ZNF337), transcript variant
            2, mRNA.
ACCESSION   NM_015655
VERSION     NM_015655.4
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 4237)
  AUTHORS   Luck,K., Kim,D.K., Lambourne,L., Spirohn,K., Begg,B.E., Bian,W.,
            Brignall,R., Cafarelli,T., Campos-Laborie,F.J., Charloteaux,B.,
            Choi,D., Cote,A.G., Daley,M., Deimling,S., Desbuleux,A., Dricot,A.,
            Gebbia,M., Hardy,M.F., Kishore,N., Knapp,J.J., Kovacs,I.A.,
            Lemmens,I., Mee,M.W., Mellor,J.C., Pollis,C., Pons,C.,
            Richardson,A.D., Schlabach,S., Teeking,B., Yadav,A., Babor,M.,
            Balcha,D., Basha,O., Bowman-Colin,C., Chin,S.F., Choi,S.G.,
            Colabella,C., Coppin,G., D'Amata,C., De Ridder,D., De Rouck,S.,
            Duran-Frigola,M., Ennajdaoui,H., Goebels,F., Goehring,L., Gopal,A.,
            Haddad,G., Hatchi,E., Helmy,M., Jacob,Y., Kassa,Y., Landini,S.,
            Li,R., van Lieshout,N., MacWilliams,A., Markey,D., Paulson,J.N.,
            Rangarajan,S., Rasla,J., Rayhan,A., Rolland,T., San-Miguel,A.,
            Shen,Y., Sheykhkarimli,D., Sheynkman,G.M., Simonovsky,E., Tasan,M.,
            Tejeda,A., Tropepe,V., Twizere,J.C., Wang,Y., Weatheritt,R.J.,
            Weile,J., Xia,Y., Yang,X., Yeger-Lotem,E., Zhong,Q., Aloy,P.,
            Bader,G.D., De Las Rivas,J., Gaudet,S., Hao,T., Rak,J.,
            Tavernier,J., Hill,D.E., Vidal,M., Roth,F.P. and Calderwood,M.A.
  TITLE     A reference map of the human binary protein interactome
  JOURNAL   Nature 580 (7803), 402-408 (2020)
   PUBMED   32296183
REFERENCE   2  (bases 1 to 4237)
  AUTHORS   Deloukas,P., Matthews,L.H., Ashurst,J., Burton,J., Gilbert,J.G.,
            Jones,M., Stavrides,G., Almeida,J.P., Babbage,A.K., Bagguley,C.L.,
            Bailey,J., Barlow,K.F., Bates,K.N., Beard,L.M., Beare,D.M.,
            Beasley,O.P., Bird,C.P., Blakey,S.E., Bridgeman,A.M., Brown,A.J.,
            Buck,D., Burrill,W., Butler,A.P., Carder,C., Carter,N.P.,
            Chapman,J.C., Clamp,M., Clark,G., Clark,L.N., Clark,S.Y.,
            Clee,C.M., Clegg,S., Cobley,V.E., Collier,R.E., Connor,R.,
            Corby,N.R., Coulson,A., Coville,G.J., Deadman,R., Dhami,P.,
            Dunn,M., Ellington,A.G., Frankland,J.A., Fraser,A., French,L.,
            Garner,P., Grafham,D.V., Griffiths,C., Griffiths,M.N., Gwilliam,R.,
            Hall,R.E., Hammond,S., Harley,J.L., Heath,P.D., Ho,S., Holden,J.L.,
            Howden,P.J., Huckle,E., Hunt,A.R., Hunt,S.E., Jekosch,K.,
            Johnson,C.M., Johnson,D., Kay,M.P., Kimberley,A.M., King,A.,
            Knights,A., Laird,G.K., Lawlor,S., Lehvaslaiho,M.H., Leversha,M.,
            Lloyd,C., Lloyd,D.M., Lovell,J.D., Marsh,V.L., Martin,S.L.,
            McConnachie,L.J., McLay,K., McMurray,A.A., Milne,S., Mistry,D.,
            Moore,M.J., Mullikin,J.C., Nickerson,T., Oliver,K., Parker,A.,
            Patel,R., Pearce,T.A., Peck,A.I., Phillimore,B.J.,
            Prathalingam,S.R., Plumb,R.W., Ramsay,H., Rice,C.M., Ross,M.T.,
            Scott,C.E., Sehra,H.K., Shownkeen,R., Sims,S., Skuce,C.D.,
            Smith,M.L., Soderlund,C., Steward,C.A., Sulston,J.E., Swann,M.,
            Sycamore,N., Taylor,R., Tee,L., Thomas,D.W., Thorpe,A., Tracey,A.,
            Tromans,A.C., Vaudin,M., Wall,M., Wallis,J.M., Whitehead,S.L.,
            Whittaker,P., Willey,D.L., Williams,L., Williams,S.A., Wilming,L.,
            Wray,P.W., Hubbard,T., Durbin,R.M., Bentley,D.R., Beck,S. and
            Rogers,J.
  TITLE     The DNA sequence and comparative analysis of human chromosome 20
  JOURNAL   Nature 414 (6866), 865-871 (2001)
   PUBMED   11780052
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BP201424.1, AK291235.1, BC021298.2, AL031673.19 and BX113975.1.
            This sequence is a reference standard in the RefSeqGene project.
            
            On Nov 22, 2018 this sequence version replaced NM_015655.3.
            
            Summary: This gene encodes a zinc finger domain containing protein.
            The function of this protein has yet to be determined. Alternative
            splicing results in multiple transcript variants. [provided by
            RefSeq, Mar 2014].
            
            Transcript Variant: This variant (2) differs in the 5' UTR,
            compared to variant 1. Variants 1 and 2 encode the same protein.
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR1803617.268215.1,
                                           SRR3476690.163167.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA1965299, SAMEA1966682
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000252979.6/ ENSP00000252979.5
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-12                BP201424.1         52-63
            13-287              AK291235.1         1-275
            288-3217            BC021298.2         268-3197
            3218-3950           AL031673.19        79894-80626         c
            3951-4237           BX113975.1         1-287
FEATURES             Location/Qualifiers
     source          1..4237
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="20"
                     /map="20p11.21"
     gene            1..4237
                     /gene="ZNF337"
                     /note="zinc finger protein 337"
                     /db_xref="GeneID:26152"
                     /db_xref="HGNC:HGNC:15809"
     exon            1..95
                     /gene="ZNF337"
                     /inference="alignment:Splign:2.1.0"
     exon            96..171
                     /gene="ZNF337"
                     /inference="alignment:Splign:2.1.0"
     CDS             145..2400
                     /gene="ZNF337"
                     /codon_start=1
                     /product="zinc finger protein 337"
                     /protein_id="NP_056470.1"
                     /db_xref="CCDS:CCDS13174.1"
                     /db_xref="GeneID:26152"
                     /db_xref="HGNC:HGNC:15809"
                     /translation="MGPQGARRQAFLAFGDVTVDFTQKEWRLLSPAQRALYREVTLEN
                     YSHLVSLGILHSKPELIRRLEQGEVPWGEERRRRPGPCAGIYAEHVLRPKNLGLAHQR
                     QQQLQFSDQSFQSDTAEGQEKEKSTKPMAFSSPPLRHAVSSRRRNSVVEIESSQGQRE
                     NPTEIDKVLKGIENSRWGAFKCAERGQDFSRKMMVIIHKKAHSRQKLFTCRECHQGFR
                     DESALLLHQNTHTGEKSYVCSVCGRGFSLKANLLRHQRTHSGEKPFLCKVCGRGYTSK
                     SYLTVHERTHTGEKPYECQECGRRFNDKSSYNKHLKAHSGEKPFVCKECGRGYTNKSY
                     FVVHKRIHSGEKPYRCQECGRGFSNKSHLITHQRTHSGEKPFACRQCKQSFSVKGSLL
                     RHQRTHSGEKPFVCKDCERSFSQKSTLVYHQRTHSGEKPFVCRECGQGFIQKSTLVKH
                     QITHSEEKPFVCKDCGRGFIQKSTFTLHQRTHSEEKPYGCRECGRRFRDKSSYNKHLR
                     AHLGEKRFFCRDCGRGFTLKPNLTIHQRTHSGEKPFMCKQCEKSFSLKANLLRHQWTH
                     SGERPFNCKDCGRGFILKSTLLFHQKTHSGEKPFICSECGQGFIWKSNLVKHQLAHSG
                     KQPFVCKECGRGFNWKGNLLTHQRTHSGEKPFVCNVCGQGFSWKRSLTRHHWRIHSKE
                     KPFVCQECKRGYTSKSDLTVHERIHTGERPYECQECGRKFSNKSYYSKHLKRHLREKR
                     FCTGSVGEASS"
     exon            172..298
                     /gene="ZNF337"
                     /inference="alignment:Splign:2.1.0"
     exon            299..394
                     /gene="ZNF337"
                     /inference="alignment:Splign:2.1.0"
     exon            395..4237
                     /gene="ZNF337"
                     /inference="alignment:Splign:2.1.0"
     regulatory      3198..3203
                     /regulatory_class="polyA_signal_sequence"
                     /gene="ZNF337"
                     /note="hexamer: AATAAA"
     polyA_site      3217
                     /gene="ZNF337"
                     /note="major polyA site"
     regulatory      3304..3309
                     /regulatory_class="polyA_signal_sequence"
                     /gene="ZNF337"
                     /note="hexamer: AATAAA"
     polyA_site      3330
                     /gene="ZNF337"
     regulatory      4217..4222
                     /regulatory_class="polyA_signal_sequence"
                     /gene="ZNF337"
                     /note="hexamer: ATTAAA"
     polyA_site      4237
                     /gene="ZNF337"
ORIGIN      
        1 gcagagcgtt ccagatccct gggcgtcagc gagccgtgag atgcgtggtc caccatcggt
       61 gacctcaccg cctcggttcg ccctcagccg ccccgattgg ccatctgcaa gcttcccttc
      121 tccgtggaga gcaggaagac agtcatggga cctcagggag ccaggagaca ggctttcttg
      181 gcatttgggg atgtcactgt ggatttcacc cagaaggaat ggaggctgct gagccctgct
      241 cagagggccc tgtacaggga ggtgacactg gagaactaca gccacctggt ctcactagga
      301 attctccatt ctaaaccaga actcatcagg cggctagagc aaggggaagt gccctgggga
      361 gaagagagaa gacgccggcc aggcccctgt gcaggaatat atgcagaaca tgtcctgcgg
      421 cccaagaatc ttggacttgc acatcagagg caacagcaac tacaattttc tgatcaaagc
      481 ttccagagtg acacagctga aggtcaagag aaagaaaaaa gcactaagcc catggcattt
      541 tccagcccac ccctaagaca tgcagtaagc tcaaggagga ggaacagtgt agtggaaata
      601 gagtctagtc aaggccagag ggaaaatcct acagaaatag acaaagtatt gaaaggaata
      661 gaaaattcaa gatggggagc attcaagtgt gcagagcgtg ggcaagactt cagccggaag
      721 atgatggtaa tcatacacaa aaaagcacat tccaggcaga aactttttac atgcagggag
      781 tgtcaccagg gctttagaga tgagtcagca ttgctcttgc accagaacac acacacagga
      841 gagaagtcct atgtgtgcag tgtgtgtggg cgaggcttca gcctcaaggc caacctcctc
      901 agacaccaga ggacacactc aggagagaag ccttttctgt gcaaggtgtg tggacgaggc
      961 tataccagta agtcatacct cactgtgcat gagagaacac acacaggaga gaagccttat
     1021 gaatgccagg agtgtgggcg aaggtttaac gataagtcct catacaacaa gcacttgaag
     1081 gcgcattcag gggagaagcc ttttgtgtgc aaggagtgtg ggcgaggcta tactaataag
     1141 tcatacttcg ttgtgcacaa gagaatacac tcaggagaga agccttacag atgccaggag
     1201 tgtggccgag gctttagcaa taagtcacac cttatcacac accagaggac acactcaggg
     1261 gagaagccct ttgcgtgcag gcagtgtaag caaagtttta gcgtgaaagg aagtctcctc
     1321 agacaccaga gaacacactc aggggagaag ccttttgtgt gcaaggattg tgagcgaagc
     1381 tttagccaaa agtcaactct tgtctaccac cagagaacac actcagggga gaaacctttt
     1441 gtttgtagag aatgtgggca aggatttatt cagaagtcaa cccttgtgaa acatcagatc
     1501 acacactcag aggagaagcc ttttgtgtgc aaggactgtg gacgaggctt tatccaaaag
     1561 tcaaccttca ctttacacca gaggacacac tcagaggaga agccttatgg atgtcgggag
     1621 tgtgggcgaa ggtttcggga taagtcctcc tataacaagc acctgagggc acacttgggt
     1681 gagaaacgtt ttttctgcag ggattgtggg cgaggcttta ccttgaagcc aaatctcacc
     1741 atacatcaga ggacacactc aggagagaag cccttcatgt gcaagcagtg tgagaaaagt
     1801 tttagtttga aggcaaatct tcttagacat cagtggacac actcggggga aaggccattt
     1861 aattgcaagg attgcgggcg aggcttcatc ctaaaatcaa ctctcctctt ccaccagaag
     1921 acacactcag gggagaagcc tttcatctgt agtgaatgtg ggcaaggatt tatctggaag
     1981 tcaaatcttg tgaaacacca gcttgcacat tctggcaagc agccttttgt atgcaaggag
     2041 tgtgggcgag gcttcaactg gaagggaaat ctcctcacac accagaggac acactcaggg
     2101 gagaagccct tcgtgtgtaa tgtgtgtggg caaggcttca gctggaagag aagtctcacc
     2161 agacaccact ggcggataca ctcaaaggag aagccttttg tttgccagga gtgtaagcga
     2221 ggctatacca gtaagtcaga cctcactgtg catgaaagaa tacacacagg agagaggcct
     2281 tatgaatgcc aagagtgtgg acgaaagttt agcaataagt catactacag taagcactta
     2341 aagagacact tacgtgagaa gcgtttttgt acagggagtg tgggtgaggc ttcatcttga
     2401 agttatatct caccatccat cagaggacac actcaggaga gtaactttgc tttgttacaa
     2461 gctttagttg aggctgcata acttgttcgt gaagatataa cagaggcaga cagaatccag
     2521 agggctacag agaacctgaa ttcaacccat gtgtccccaa gagattcaga gaaaagaggt
     2581 caatgtttag ggaacagaga tgccagttga ggggagggca ttacctgggc tattggggaa
     2641 atgtggtctc tttcctactg agcacatatt cttgttgtat ttgtgccagg ctgtgctttc
     2701 taaggactgc tcttagccag tgactgcaga gcagggatac caaggcaggc ctgttacact
     2761 ctccccaacc tccttggact gcaaacaatc taggacacct ccaccaaacc tcctcttgca
     2821 ctttccctct ggcttccctc ccagccttcc ttggtttgga tgttttgtcc cctccttaat
     2881 ttatgttgaa actctacata aactgtttac tgttgaaaca gtgtaagtat taggaggtgg
     2941 gacctttggg aagtgattaa gtcaagtcac gaagatagag ctttgcgaat gggatcaggt
     3001 gcccttatga aaaggcttga tagagggagt ttgtcctgtg gcccttctat tttctgctct
     3061 gtgaggacac aatgctcctc ccttccaaaa gatgcagcat gaaggcatca tcttggaaac
     3121 agacatgagc cctcaacaga caactgcacc tactgatgtt ttgatgttga acttcccagc
     3181 ctccagaact ctgggaaaat aaagtcctct ttatacattt cctagtcagt ggtattttat
     3241 tataacagct caaatagact aagtaactgc tcccctcatc attctctcac agtcatatct
     3301 ggaaataaaa tctctgtata tgcagtccca tattggtctt tgcagagaac tccctccaac
     3361 acagctgata ccaagaacag tctgacaaaa caagtggtaa aatagggatc tggggaccac
     3421 tcacctgcct ggcaggagta aagcatgttg gctggtgggg cacaggtagg tggttagctg
     3481 caaaatattt cacaggtgat ttcctgagaa aatgcctcaa tgatagagaa tgctgtggca
     3541 gatgtgatga tgcaggcctt tgaaaatgta gggaaagtgc ctacaaagag cagagtagac
     3601 tgattatcgc cgatctgcat taccacctgc agaaggacct tgagaaattg aagacttcat
     3661 tcagccatta gcaaacagtt aatggttaag taaaccagga ctccctggtg agtgcttaca
     3721 aggcctttat cttcttggat agaaggcaga attattgccc aaatatgtgg gctgaaggcc
     3781 tgtagcagag ctctacagat gttggaatgc tcagccaatg catgtctatt ttgtagaggt
     3841 cagacccttc gtaaggaaaa tctgggatcc tgaaaaatga caccggaaca tctccatgga
     3901 tgcccaagat tgcctctgcc atgctcccag ccacagacca tctgggtgtg tagagatggc
     3961 ccatccttcc ttaggaatag catttccacc attcattacc acagaacctt cacaattaag
     4021 gccagcttaa tgagcatgtg ccctacatag ctgcacacaa cccttgtcca gcacagggaa
     4081 gatacatgca atatgcctat ccttttgtaa atggtatttg tgatgcttgc ccttcaactt
     4141 ccataacttt cctcatactc attttgagtt tcactgcaca ttgtgggttc accagaattc
     4201 tgtgctcctc ttccatatta aacacattta catctga
//
