LOCUS       NM_024620               3501 bp    mRNA    linear   PRI 03-OCT-2024
DEFINITION  Homo sapiens zinc finger protein 329 (ZNF329), mRNA.
ACCESSION   NM_024620
VERSION     NM_024620.4
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 3501)
  AUTHORS   Lovering,R.C., Gaudet,P., Acencio,M.L., Ignatchenko,A., Jolma,A.,
            Fornes,O., Kuiper,M., Kulakovskiy,I.V., Laegreid,A., Martin,M.J.
            and Logie,C.
  TITLE     A GO catalogue of human DNA-binding transcription factors
  JOURNAL   Biochim Biophys Acta Gene Regul Mech 1864 (11-12), 194765 (2021)
   PUBMED   34673265
REFERENCE   2  (bases 1 to 3501)
  AUTHORS   Luck,K., Kim,D.K., Lambourne,L., Spirohn,K., Begg,B.E., Bian,W.,
            Brignall,R., Cafarelli,T., Campos-Laborie,F.J., Charloteaux,B.,
            Choi,D., Cote,A.G., Daley,M., Deimling,S., Desbuleux,A., Dricot,A.,
            Gebbia,M., Hardy,M.F., Kishore,N., Knapp,J.J., Kovacs,I.A.,
            Lemmens,I., Mee,M.W., Mellor,J.C., Pollis,C., Pons,C.,
            Richardson,A.D., Schlabach,S., Teeking,B., Yadav,A., Babor,M.,
            Balcha,D., Basha,O., Bowman-Colin,C., Chin,S.F., Choi,S.G.,
            Colabella,C., Coppin,G., D'Amata,C., De Ridder,D., De Rouck,S.,
            Duran-Frigola,M., Ennajdaoui,H., Goebels,F., Goehring,L., Gopal,A.,
            Haddad,G., Hatchi,E., Helmy,M., Jacob,Y., Kassa,Y., Landini,S.,
            Li,R., van Lieshout,N., MacWilliams,A., Markey,D., Paulson,J.N.,
            Rangarajan,S., Rasla,J., Rayhan,A., Rolland,T., San-Miguel,A.,
            Shen,Y., Sheykhkarimli,D., Sheynkman,G.M., Simonovsky,E., Tasan,M.,
            Tejeda,A., Tropepe,V., Twizere,J.C., Wang,Y., Weatheritt,R.J.,
            Weile,J., Xia,Y., Yang,X., Yeger-Lotem,E., Zhong,Q., Aloy,P.,
            Bader,G.D., De Las Rivas,J., Gaudet,S., Hao,T., Rak,J.,
            Tavernier,J., Hill,D.E., Vidal,M., Roth,F.P. and Calderwood,M.A.
  TITLE     A reference map of the human binary protein interactome
  JOURNAL   Nature 580 (7803), 402-408 (2020)
   PUBMED   32296183
REFERENCE   3  (bases 1 to 3501)
  AUTHORS   Fragoza,R., Das,J., Wierbowski,S.D., Liang,J., Tran,T.N., Liang,S.,
            Beltran,J.F., Rivera-Erick,C.A., Ye,K., Wang,T.Y., Yao,L., Mort,M.,
            Stenson,P.D., Cooper,D.N., Wei,X., Keinan,A., Schimenti,J.C.,
            Clark,A.G. and Yu,H.
  TITLE     Extensive disruption of protein interactions by genetic variants
            across the allele frequency spectrum in human populations
  JOURNAL   Nat Commun 10 (1), 4141 (2019)
   PUBMED   31515488
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 3501)
  AUTHORS   Zhang,L., Feng,X.K., Ng,Y.K. and Li,S.C.
  TITLE     Reconstructing directed gene regulatory network by only gene
            expression data
  JOURNAL   BMC Genomics 17 Suppl 4 (Suppl 4), 430 (2016)
   PUBMED   27556418
  REMARK    GeneRIF: TYROBP influences a batch of genes that are related to
            Alzheimer's disease; ZNF329 and RB1 significantly regulate those
            'mesenchymal' gene expression signature genes for brain tumors.  By
            merely leveraging gene expression data, Context Based Dependency
            Network (CBDN) can efficiently infer the existence of gene-gene
            interactions as well as their regulatory directions.
            Publication Status: Online-Only
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC008751.7, AK095349.1 and BC047501.1.
            
            On Nov 23, 2018 this sequence version replaced NM_024620.3.
            
            ##Evidence-Data-START##
            Transcript exon combination :: DB033762.1, SRR1660809.244312.1
                                           [ECO:0000332]
            RNAseq introns              :: partial sample support SAMEA1965299,
                                           SAMEA1968540 [ECO:0000350]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000598312.6/ ENSP00000470008.1
            RefSeq Select criteria :: based on conservation
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-8                 AC008751.7         130723-130730       c
            9-11                AK095349.1         7-9
            12-609              BC047501.1         1-598
            610-2272            AK095349.1         1043-2705
            2273-2299           BC047501.1         2262-2288
            2300-3131           AC008751.7         106559-107390       c
            3132-3421           BC047501.1         3122-3411
            3422-3501           AC008751.7         106189-106268       c
FEATURES             Location/Qualifiers
     source          1..3501
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="19"
                     /map="19q13.43"
     gene            1..3501
                     /gene="ZNF329"
                     /note="zinc finger protein 329"
                     /db_xref="GeneID:79673"
                     /db_xref="HGNC:HGNC:14209"
     exon            1..38
                     /gene="ZNF329"
                     /inference="alignment:Splign:2.1.0"
     exon            39..132
                     /gene="ZNF329"
                     /inference="alignment:Splign:2.1.0"
     exon            133..237
                     /gene="ZNF329"
                     /inference="alignment:Splign:2.1.0"
     exon            238..3501
                     /gene="ZNF329"
                     /inference="alignment:Splign:2.1.0"
     CDS             246..1871
                     /gene="ZNF329"
                     /codon_start=1
                     /product="zinc finger protein 329"
                     /protein_id="NP_078896.3"
                     /db_xref="CCDS:CCDS12972.1"
                     /db_xref="GeneID:79673"
                     /db_xref="HGNC:HGNC:14209"
                     /translation="MRLKMTTRNFPEREVPCDVEVERFTREVPCLSSLGDGWDCENQE
                     GHLRQSALTLEKPGTQEAICEYPGFGEHLIASSDLPPSQRVLATNGFHAPDSNVSGLD
                     CDPALPSYPKSYADKRTGDSDACGKGFNHSMEVIHGRNPVREKPYKYPESVKSFNHFT
                     SLGHQKIMKRGKKSYEGKNFENIFTLSSSLNENQRNLPGEKQYRCTECGKCFKRNSSL
                     VLHHRTHTGEKPYTCNECGKSFSKNYNLIVHQRIHTGEKPYECSKCGKAFSDGSALTQ
                     HQRIHTGEKPYECLECGKTFNRNSSLILHQRTHTGEKPYRCNECGKPFTDISHLTVHL
                     RIHTGEKPYECSKCGKAFRDGSYLTQHERTHTGEKPFECAECGKSFNRNSHLIVHQKI
                     HSGEKPYECKECGKTFIESAYLIRHQRIHTGEKPYGCNQCQKLFRNIAGLIRHQRTHT
                     GEKPYECNQCGKAFRDSSCLTKHQRIHTKETPYQCPECGKSFKQNSHLAVHQRLHSRE
                     GPSRCPQCGKMFQKSSSLVRHQRAHLGEQPMET"
     regulatory      3391..3396
                     /regulatory_class="polyA_signal_sequence"
                     /gene="ZNF329"
                     /note="hexamer: AATAAA"
     polyA_site      3421
                     /gene="ZNF329"
                     /note="major polyA site"
     regulatory      3482..3487
                     /regulatory_class="polyA_signal_sequence"
                     /gene="ZNF329"
                     /note="hexamer: ATTAAA"
     polyA_site      3501
                     /gene="ZNF329"
ORIGIN      
        1 gcaatcgccc ggaacatggc tgccgccggc cgccaaccgg tcttgctgtc tcacccaggc
       61 tggagtgcag tggcacgatc acagctcact gcagccttga gctcctgggc taccaagtag
      121 ctgggacttc agagatggct ggagccgtgt ggatgggcat aaatggctaa tgtccagcaa
      181 ccatcgatgt caagtatcca cacacctggc ctgaatggat ccctctgcct ttcagagttt
      241 gggatatgag attgaaaatg acgactcgga attttcctga gagagaagta ccctgtgatg
      301 tagaagtgga aagattcaca agggaagttc cctgcttgtc cagtttaggt gatggttggg
      361 actgtgagaa ccaggaggga cacttgaggc aatcagcttt aactctggag aaaccaggga
      421 ctcaggaagc aatttgtgaa tatcctggtt ttggggagca tttgattgca agctcagacc
      481 ttccaccgtc tcagagagtt ctggcaacaa atggtttcca tgcacctgac tcaaatgtta
      541 gtggtctgga ttgtgacccc gccttaccca gctatcctaa aagttatgca gataagagaa
      601 ctggtgacag tgatgcctgt ggaaaaggct tcaaccattc catggaagtt attcatggaa
      661 gaaatccagt gagagagaag ccctacaaat accctgaaag tgttaagtct tttaatcatt
      721 ttacctctct tggtcatcag aaaataatga aaagaggcaa gaaatcgtat gaaggtaaga
      781 attttgagaa catctttact ctgagctcat cgcttaatga aaaccagaga aatctccctg
      841 gagagaaaca atatagatgt actgaatgtg gcaaatgctt caaacggaac tcttctcttg
      901 ttttgcatca ccgaactcac accggagaga agccttatac ttgtaatgag tgtggaaagt
      961 ccttctccaa gaactacaac ctgattgtgc atcaaagaat ccacacagga gagaagccct
     1021 atgaatgcag taaatgtggg aaagctttca gtgatggctc agctctgaca cagcaccaga
     1081 gaattcacac aggcgagaaa ccttatgaat gcctagagtg tggaaaaacc ttcaaccgaa
     1141 attcatcctt aattttgcac caaagaactc atacagggga aaaaccatat agatgtaacg
     1201 aatgtgggaa acccttcact gacatctccc accttacagt gcatctcaga atccacaccg
     1261 gtgagaagcc ctatgagtgt agcaaatgtg gaaaggcttt ccgggacggc tcgtacctca
     1321 cccagcatga gaggactcac actggagaaa agccctttga gtgtgcagag tgcgggaaat
     1381 ccttcaacag aaactctcac ctcattgtgc atcaaaagat ccattctggg gagaaaccct
     1441 atgaatgtaa agaatgtggc aagactttca tcgagagtgc gtacctcatc aggcatcaga
     1501 ggattcatac tggcgagaag ccctatggct gcaaccagtg tcagaaactt ttcaggaata
     1561 tcgctggcct cattaggcac cagaggactc atactggtga gaagccctat gagtgtaatc
     1621 agtgtggcaa agccttcagg gacagctcct gtctgaccaa gcaccagaga attcacacta
     1681 aggagacccc atatcagtgt ccagaatgtg ggaagtcctt caagcagaac tctcacctgg
     1741 cagtacatca gagactccat agcagggagg gtcccagccg gtgtcctcag tgtggaaaaa
     1801 tgttccaaaa gagctcatcc cttgttcgac atcaaagagc acacctggga gagcaaccca
     1861 tggaaacata atggttgggg gccacatgag tcttccagtt cactctcact cctgtgttta
     1921 ggaggcgtgt cttagatctg actcctctct ggtcagtaga aaagaatcct ttaagctatc
     1981 cagtgaattg atgaatgtga gacattgctg agccacactg ttaagtctgc tcattgggga
     2041 actccagaga caacttagga tgagggcaga aaagtctttg gggatgattc agtctgtacc
     2101 agacatgaca acacacacac tggaatgaaa tgtgcaaaca tgggggtgac accacagaga
     2161 gaacctgtga atgcattcag aacatgattg gaatgaagag ccctgtagta gggagtttcc
     2221 accttgtacg taagcaaaca ctgaatcaac tttttttttt ttttcggaca gagtctcact
     2281 gtgcagtggc atgatctcca ctcacagcaa cctctgcctc ccaggttcaa gcagttctcc
     2341 tgcctcagcc tccaaagtag ctaggattac aggtgcctgc caccatgcct ggctaatttt
     2401 ttctattttt agtagagaca gggtttcact gtgttggcca ggctggtctt gaactcctga
     2461 cctcatgatc cgcccacctc agcctcccaa agtgttggga ttacaggcat gagacactgc
     2521 ctggcctgaa tcaacctttt ttaagtgtaa tcagaaagag aggctttggc aggggctctt
     2581 actgtgtttt ctgtaacaac aaaggtgtac aatgagagag tccacacagt gctgtactgc
     2641 acacaccaca gaatgtgtga gattttcctg tttgaatgta tgtctgcatt atactcctgc
     2701 aataatgctg aggactcgtt gcaggagggc aaactaggtg aataaattac ctgtgaatga
     2761 acaatgaagt cgttcctctt aagactgaaa caagcaggcc agatgtggtg gctcacgcct
     2821 gtaatcctag cactttggga ggccgaggcg gccagatcac aaggttagga gttcaagacc
     2881 agcctggcca gcatggtgaa accccatctc taccaaaaat acaggaaatt atctgggcat
     2941 agtagtgtgt gcctgtaatc ccagctactt gggaagctga ggcaggagaa ttgcttgaac
     3001 ctgggaggtg gaggttgcag tgagctaaga tcgcaccact gcactccagc ctgggtgaca
     3061 gagcgagact ccatttcaaa aaaaaagact gaaacaagct tgtgctaaga tggaaagggc
     3121 tgcttctaac agatgtggtt tgttgcttta gttgttgaag caaaaatact gagttgttat
     3181 gtttatgtta tcaccccacc actacctcca tggttgttca tttaggatgc ttctaattca
     3241 gccactgtga accattataa aggttttatt gccatgttga aaatgtttat aatatggcaa
     3301 aaaggggcat caaatagaag atttactatt attccagcca tgtaaaaata tgtgcacata
     3361 tggatgtatg ttgaaagtgg atgatggaga aataaaatgt ggttttcttt ggggactgga
     3421 attttgtatc atattttttt ctctgttaca gatacttgtt ggcataataa tttggtaata
     3481 aattaaaaag tgaagccaaa a
//
