LOCUS       NM_020933               4056 bp    mRNA    linear   PRI 04-APR-2024
DEFINITION  Homo sapiens zinc finger protein 317 (ZNF317), transcript variant
            1, mRNA.
ACCESSION   NM_020933
VERSION     NM_020933.5
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 4056)
  AUTHORS   Luck,K., Kim,D.K., Lambourne,L., Spirohn,K., Begg,B.E., Bian,W.,
            Brignall,R., Cafarelli,T., Campos-Laborie,F.J., Charloteaux,B.,
            Choi,D., Cote,A.G., Daley,M., Deimling,S., Desbuleux,A., Dricot,A.,
            Gebbia,M., Hardy,M.F., Kishore,N., Knapp,J.J., Kovacs,I.A.,
            Lemmens,I., Mee,M.W., Mellor,J.C., Pollis,C., Pons,C.,
            Richardson,A.D., Schlabach,S., Teeking,B., Yadav,A., Babor,M.,
            Balcha,D., Basha,O., Bowman-Colin,C., Chin,S.F., Choi,S.G.,
            Colabella,C., Coppin,G., D'Amata,C., De Ridder,D., De Rouck,S.,
            Duran-Frigola,M., Ennajdaoui,H., Goebels,F., Goehring,L., Gopal,A.,
            Haddad,G., Hatchi,E., Helmy,M., Jacob,Y., Kassa,Y., Landini,S.,
            Li,R., van Lieshout,N., MacWilliams,A., Markey,D., Paulson,J.N.,
            Rangarajan,S., Rasla,J., Rayhan,A., Rolland,T., San-Miguel,A.,
            Shen,Y., Sheykhkarimli,D., Sheynkman,G.M., Simonovsky,E., Tasan,M.,
            Tejeda,A., Tropepe,V., Twizere,J.C., Wang,Y., Weatheritt,R.J.,
            Weile,J., Xia,Y., Yang,X., Yeger-Lotem,E., Zhong,Q., Aloy,P.,
            Bader,G.D., De Las Rivas,J., Gaudet,S., Hao,T., Rak,J.,
            Tavernier,J., Hill,D.E., Vidal,M., Roth,F.P. and Calderwood,M.A.
  TITLE     A reference map of the human binary protein interactome
  JOURNAL   Nature 580 (7803), 402-408 (2020)
   PUBMED   32296183
REFERENCE   2  (bases 1 to 4056)
  AUTHORS   Fragoza,R., Das,J., Wierbowski,S.D., Liang,J., Tran,T.N., Liang,S.,
            Beltran,J.F., Rivera-Erick,C.A., Ye,K., Wang,T.Y., Yao,L., Mort,M.,
            Stenson,P.D., Cooper,D.N., Wei,X., Keinan,A., Schimenti,J.C.,
            Clark,A.G. and Yu,H.
  TITLE     Extensive disruption of protein interactions by genetic variants
            across the allele frequency spectrum in human populations
  JOURNAL   Nat Commun 10 (1), 4141 (2019)
   PUBMED   31515488
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 4056)
  AUTHORS   de Mateo,S., Castillo,J., Estanyol,J.M., Ballesca,J.L. and Oliva,R.
  TITLE     Proteomic characterization of the human sperm nucleus
  JOURNAL   Proteomics 11 (13), 2714-2726 (2011)
   PUBMED   21630459
REFERENCE   4  (bases 1 to 4056)
  AUTHORS   Yu,H., Tardivo,L., Tam,S., Weiner,E., Gebreab,F., Fan,C.,
            Svrzikapa,N., Hirozane-Kishikawa,T., Rietman,E., Yang,X.,
            Sahalie,J., Salehi-Ashtiani,K., Hao,T., Cusick,M.E., Hill,D.E.,
            Roth,F.P., Braun,P. and Vidal,M.
  TITLE     Next-generation sequencing to generate interactome datasets
  JOURNAL   Nat Methods 8 (6), 478-480 (2011)
   PUBMED   21516116
REFERENCE   5  (bases 1 to 4056)
  AUTHORS   Takashima,H., Nishio,H., Wakao,H., Nishio,M., Koizumi,K., Oda,A.,
            Koike,T. and Sawada,K.
  TITLE     Molecular cloning and characterization of a KRAB-containing zinc
            finger protein, ZNF317, and its isoforms
  JOURNAL   Biochem Biophys Res Commun 288 (4), 771-779 (2001)
   PUBMED   11688974
  REMARK    GeneRIF: molecular cloning and characterization of isoforms
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            DA757943.1 and BC078154.1.
            
            On Nov 22, 2018 this sequence version replaced NM_020933.4.
            
            Transcript Variant: This variant (1) encodes the longer isoform
            (1).
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK056570.1, SRR1803611.199849.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA1965299, SAMEA1966682
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000247956.11/ ENSP00000247956.5
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-515               DA757943.1         18-532
            516-4056            BC078154.1         503-4043
FEATURES             Location/Qualifiers
     source          1..4056
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="19"
                     /map="19p13.2"
     gene            1..4056
                     /gene="ZNF317"
                     /note="zinc finger protein 317"
                     /db_xref="GeneID:57693"
                     /db_xref="HGNC:HGNC:13507"
                     /db_xref="MIM:613864"
     exon            1..196
                     /gene="ZNF317"
                     /inference="alignment:Splign:2.1.0"
     exon            197..313
                     /gene="ZNF317"
                     /inference="alignment:Splign:2.1.0"
     CDS             289..2076
                     /gene="ZNF317"
                     /note="isoform 1 is encoded by transcript variant 1;
                     KRAB-containing zinc finger protein 317"
                     /codon_start=1
                     /product="zinc finger protein 317 isoform 1"
                     /protein_id="NP_065984.3"
                     /db_xref="CCDS:CCDS12210.1"
                     /db_xref="GeneID:57693"
                     /db_xref="HGNC:HGNC:13507"
                     /db_xref="MIM:613864"
                     /translation="MAALSPTFATSTQDSTCLQDSEFPVSSKDHSCPQNLDLFVCSGL
                     EPHTPSVGSQESVTFQDVAVDFTEKEWPLLDSSQRKLYKDVMLENYSNLTSLGYQVGK
                     PSLISHLEQEEEPRTEERGAHQGACADWETPSKTKWSLLMEDIFGKETPSGVTMERAG
                     LGEKSTEYAHLFEVFGMDPHLTQPMGRHAGKRPYHRRDYGVAFKGRPHLTQHMSMYDG
                     RKMHECHQCQKAFTTSASLTRHRRIHTGEKPYECSDCGKAFNDPSALRSHARTHLKEK
                     PFDCSQCGNAFRTLSALKIHMRVHTGERPYKCDQCGKAYGRSCHLIAHKRTHTGERPY
                     ECHDCGKAFQHPSHLKEHVRNHTGEKPYACTQCGKAFRWKSNFNLHKKNHMVEKTYEC
                     KECGKSFGDLVSRRKHMRIHIVKKPVECRQCGKTFRNQSILKTHMNSHTGEKPYGCDL
                     CGKAFSASSNLTAHRKIHTQERRYECAACGKVFGDYLSRRRHMSVHLVKKRVECRQCG
                     KAFRNQSTLKTHMRSHTGEKPYECDHCGKAFSIGSNLNVHRRIHTGEKPYECLVCGKA
                     FSDHSSLRSHVKTHRGEKLFVSSVWKRLQ"
     exon            314..450
                     /gene="ZNF317"
                     /inference="alignment:Splign:2.1.0"
     exon            451..577
                     /gene="ZNF317"
                     /inference="alignment:Splign:2.1.0"
     exon            578..673
                     /gene="ZNF317"
                     /inference="alignment:Splign:2.1.0"
     exon            674..756
                     /gene="ZNF317"
                     /inference="alignment:Splign:2.1.0"
     exon            757..4056
                     /gene="ZNF317"
                     /inference="alignment:Splign:2.1.0"
     regulatory      4029..4034
                     /regulatory_class="polyA_signal_sequence"
                     /gene="ZNF317"
                     /note="hexamer: AATAAA"
     polyA_site      4056
                     /gene="ZNF317"
                     /note="major polyA site"
ORIGIN      
        1 agtgaagcgg aagccattac tctctggagt cgattgcccc gagacacatg ggccaaggag
       61 gggtcagcgg cgaattcttt cggcctgttg gggacccctc gtgtccccac gccagactgg
      121 acctcccgta tgaacttctc ttcgcatcgg cggcggcttc cgtcacctcc gctcccccga
      181 tcctattccc agtcgtatgc cagcttggag agtcacgtga gagcaagaga gtagctttct
      241 ggttgtcctg gtgccctgct caggcaaact gactgccatt ctctgaggat ggcagctctg
      301 tcccccacat ttgccacgtc cacccaggat tccacctgtc tccaggactc agaatttcct
      361 gtttcttcaa aagaccattc ctgtccccag aatttggacc tgttcgtgtg cagtggtctg
      421 gagcctcaca cacccagtgt tggttcccag gaatcggtga ctttccaaga tgtcgctgtg
      481 gactttaccg agaaggagtg gcccttgctg gattcttctc agagaaaact gtacaaagat
      541 gtaatgctgg agaactacag caacctcact tcactggggt atcaggtcgg caaacccagc
      601 ctcatctcac acttggagca ggaggaggag ccgaggacag aggagagggg cgctcaccag
      661 ggcgcttgtg cagattggga gactccatct aaaaccaagt ggtcacttct tatggaagat
      721 atttttggga aggaaacgcc cagtggtgtg acgatggaaa gagccggtct tggagagaag
      781 tccactgaat acgctcactt gttcgaagtc tttggcatgg accctcatct cactcagcca
      841 atgggaaggc acgctggcaa gaggccctat caccgccgcg actatggggt agcgttcaag
      901 ggcaggccgc acctcactca gcacatgagc atgtacgacg ggagaaaaat gcatgaatgt
      961 catcagtgcc aaaaagcctt caccacgagc gcgtccctca cacggcacag gagaatccac
     1021 accggggaga agccttacga gtgcagcgac tgcgggaaag ccttcaacga cccttcagcc
     1081 cttaggagcc acgcaagaac tcacctcaaa gagaagccct ttgactgcag tcagtgtgga
     1141 aatgcattcc ggaccctctc ggccctgaaa atccacatgc gagttcacac tggcgagagg
     1201 ccttacaagt gtgatcagtg cgggaaggct tacggccgga gctgccacct catcgcacac
     1261 aagagaacgc acaccggaga gaggccctac gagtgtcacg actgtgggaa agctttccag
     1321 cacccctccc acctcaaaga gcacgtgagg aatcacacgg gggagaagcc ctacgcgtgc
     1381 acgcagtgcg gcaaagcctt ccgctggaag tccaacttta atttgcacaa gaagaaccac
     1441 atggtggaga agacctacga atgtaaagaa tgcgggaaat cctttggcga tctcgtgtcc
     1501 cggaggaaac acatgaggat tcacatcgtc aagaaacccg tggaatgtcg gcagtgcggg
     1561 aagaccttcc gaaaccagtc catccttaag actcacatga actctcacac tggagagaaa
     1621 ccatacgggt gcgatctctg cgggaaagct ttcagcgcga gttcaaacct caccgcacac
     1681 aggaagatac acacgcaaga gagacgctac gaatgcgccg cctgcgggaa agtcttcggt
     1741 gactatttat cccggcggag gcacatgagc gttcaccttg taaagaaacg agttgagtgt
     1801 aggcagtgtg gcaaggcctt caggaaccag tcaacgctga agacgcacat gcgaagccac
     1861 acgggggaga aaccgtacga atgcgatcac tgtgggaagg ccttcagcat aggctccaac
     1921 ctgaatgtgc acaggcggat ccacaccggg gagaagccct acgaatgcct tgtctgcggg
     1981 aaagccttca gcgaccactc atccctcagg agccacgtga aaactcaccg gggagagaag
     2041 ctctttgtgt catccgtgtg gaaaaggctc cagtgagcgc gcctgcttta gagacacagg
     2101 atgattcaga ccggaaacag acctcgtggg tgtaagagga agcctctgtg agctcgcacc
     2161 ttactgggtg caaaagaatc cacggaactt gggagaagtc cagttcctgt aaaaactggg
     2221 aagacgaggc gttctcatcc cataggaggt ttgtgagaac tcacgccggg ggtgaaaatg
     2281 tacgtctgta gcatggagaa gccttcaggg tacattcagc tcttaacaaa cacaggagga
     2341 cttaatggca gcttggcatt taatgtcaaa atccaagccg tggcatttaa tgtcaaaatg
     2401 acttcagacc acttctagcc ttctgggccc atgagtaata atgagcacac tagggagcat
     2461 ctctgtaaac acagtggctg gggaaaccct tcctagtctc acttgattcc tcatgacgga
     2521 aatcacacta aagagagaaa tcagtgaagt aaggaacgtg gaaggtcatg aatgggccgc
     2581 aaaccacggc cagctgcttg tctttgtatg gcttgccagc taacaatagt ggttccatct
     2641 ttaaggaaga agaatgtttg atggagaaaa tttgtggcca atgaagtctg aaatacttcc
     2701 tgtcatctgc ccctttccag aaaaacttgg ccgacccttg gtctacagca cgggttctca
     2761 gtcgggcgac gatttggctg tctaggcgtc atttggcaat gtctagagac atttttggta
     2821 gttagaatgg ggggaagata ctcctgactt gtaataagaa gacatcagag atgctgctaa
     2881 gtcggctcca gcacacagga gccccccaca acgaagagtt agtgccccca aacgtcactg
     2941 ttgctgaggt tgaaaataat catgcagtca ttcctcaatt actgcctgca gcaattcctc
     3001 catttttatg aatcttgtga gcacttacgc taggagaaat ttcttttaca aaacttttaa
     3061 aatacaatta gtgctgataa ttcctatgtg gaaatgattc cagccatggt cccctcactt
     3121 gagcatgtga atattctcac ggagagaagc cccagcgaga ttttccggtg aatacgggat
     3181 tgcacttact ctttcatcac ggaaacagac cccccgagag aagccccaac gagattttcc
     3241 ggtgaatacg ggactgcacg tactctctca tcatgaaaac agagccccgt tcataaattt
     3301 ttcatcttta tttttaaggt tatactcctc taaataaccc ttaagcctca tcaagaaagg
     3361 tttgtttata gtatttttac tatagcttca tccttgataa cgtcctaatt tccttctgga
     3421 caacctcctt gaccaatggc atattgagat ctatgtgaca tgaggatatt tctcagtacc
     3481 actttgttac tggtacctga tgcacacgga ttgcgaccag agcatgatgc ctccatcaag
     3541 tggtaatatg tttgcagcct gctgtccagc caagagtgac agatacttct agtgacttcc
     3601 ccggtatcca ctctcatctt cttccaatat caagagaatc caggttctgt cagattagta
     3661 aggtgtgcta atctaaattt taaaaaatct cttacaggtt ttcttgcagc tggtaccatc
     3721 catgtctcac agccctggcc actgacagat cagcagatgt caccacatgg gcttctgaga
     3781 aagctcttga atggggatcg ttcttaaaca tgaattcctc cctgtatgtt ttgttctttg
     3841 ctttactttt caccttgcaa agagatccag tacctagtat tggaagatcc accttaacga
     3901 ccgtgcatat gaaaaccaca gtctaaggaa gtgactgcag aaagctcaca gcgaccctgg
     3961 cctcccctgt ggcctctttg agtgtctgca gcagccctgg acttccagac ttctatcaca
     4021 tgagaaaaaa taaaactgat tattggttta agctgc
//
