LOCUS       NM_194325               2580 bp    mRNA    linear   PRI 11-FEB-2024
DEFINITION  Homo sapiens zinc finger protein 30 (ZNF30), transcript variant 3,
            mRNA.
ACCESSION   NM_194325 XM_028742
VERSION     NM_194325.3
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 2580)
  AUTHORS   Vaquerizas,J.M., Kummerfeld,S.K., Teichmann,S.A. and Luscombe,N.M.
  TITLE     A census of human transcription factors: function, expression and
            evolution
  JOURNAL   Nat Rev Genet 10 (4), 252-263 (2009)
   PUBMED   19274049
  REMARK    Review article
REFERENCE   2  (bases 1 to 2580)
  AUTHORS   Thiesen,H.J.
  TITLE     Multiple genes encoding zinc finger domains are expressed in human
            T cells
  JOURNAL   New Biol 2 (4), 363-374 (1990)
   PUBMED   2288909
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            DC352784.1, DA504398.1, BC142996.1 and AK000569.1.
            
            On Jun 2, 2019 this sequence version replaced NM_194325.2.
            
            Transcript Variant: This variant (3) differs in the 5' UTR and uses
            an alternate in-frame splice site in the 5' coding region, compared
            to variant 1. The encoded protein (isoform b) is shorter than
            isoform a.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR3476690.968105.1,
                                           SRR1803617.247804.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA1968540, SAMEA1968968
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000601142.2/ ENSP00000469954.1
            RefSeq Select criteria :: based on conservation
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-96                DC352784.1         1-96
            97-646              DA504398.1         3-552
            647-1851            BC142996.1         635-1839
            1852-2580           AK000569.1         1005-1733
FEATURES             Location/Qualifiers
     source          1..2580
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="19"
                     /map="19q13.11"
     gene            1..2580
                     /gene="ZNF30"
                     /gene_synonym="KOX28"
                     /note="zinc finger protein 30"
                     /db_xref="GeneID:90075"
                     /db_xref="HGNC:HGNC:13090"
     exon            1..314
                     /gene="ZNF30"
                     /gene_synonym="KOX28"
                     /inference="alignment:Splign:2.1.0"
     exon            315..387
                     /gene="ZNF30"
                     /gene_synonym="KOX28"
                     /inference="alignment:Splign:2.1.0"
     CDS             379..2250
                     /gene="ZNF30"
                     /gene_synonym="KOX28"
                     /note="isoform b is encoded by transcript variant 3; zinc
                     finger protein 30 (KOX 28); zinc finger protein KOX28"
                     /codon_start=1
                     /product="zinc finger protein 30 isoform b"
                     /protein_id="NP_919306.2"
                     /db_xref="CCDS:CCDS46045.1"
                     /db_xref="GeneID:90075"
                     /db_xref="HGNC:HGNC:13090"
                     /translation="MAHKYVGLQYHGSVTFEDVAIAFSQQEWESLDSSQRGLYRDVML
                     ENYRNLVSMGHSRSKPHVIALLEQWKEPEVTVRKDGRRWCTDLQLEDDTIGCKEMPTS
                     ENCPSFALHQKISRQKPRECQEYGKTLCQDSKPVQHERIHSSEKPNRCKECGKNFSNG
                     HQLTIHQRLHVGEKPYKYEKCGKAFISGSAFVKHGRIHTGEKPLKCKQCGKTISGSYQ
                     LTVHKSIHTGKKPYECGECGKAFLVYGKLTRHQSTHTGEKPFGCEECGKAFSTFSYLV
                     QHQRIHTSEKPYECKECGKAFSTSSPLAKHQRIHTGEKPYECKECGKSFTVYGQLTRH
                     QSIHTGEKPFECKECGKAFRLSSFLHAHQRIHAEIKPYGCKECGRTFSRASYLVQHGR
                     LHTGEKPYECKECGKAFSTGSYLVQHQRIHTGEKPYECKECGKAFISRHQLTVHQRVH
                     TGEKPYECKECGKAFRVHVHLTQHRKIHTDVKPYECKECGKTFSRASYLVQHSRIHTG
                     KKPYECKECGKAFSSGSYLVQHQRIHTGEKPYECNKCGKAFTVYGQLIGHQSVHTGEK
                     PFECKECGKAFRLNSFLTEHQRVHTGEKPFKCKKCGKTFRYSSALKVHLRKHMSVIP"
     exon            388..538
                     /gene="ZNF30"
                     /gene_synonym="KOX28"
                     /inference="alignment:Splign:2.1.0"
     exon            539..634
                     /gene="ZNF30"
                     /gene_synonym="KOX28"
                     /inference="alignment:Splign:2.1.0"
     exon            635..2580
                     /gene="ZNF30"
                     /gene_synonym="KOX28"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2556..2561
                     /regulatory_class="polyA_signal_sequence"
                     /gene="ZNF30"
                     /gene_synonym="KOX28"
                     /note="hexamer: AATAAA"
     polyA_site      2580
                     /gene="ZNF30"
                     /gene_synonym="KOX28"
                     /note="major polyA site"
ORIGIN      
        1 cttgtggact gcgccgggca tgctcggcgg tgtgacggct caggactgca tttcccagag
       61 gctgcagcta tccggccaat gtagcctgaa actacatttc tcagcggcca ctggaacgac
      121 ctcaatctct gcctcctcgc cagttcattg tggtcgttga cccggcagcg agctttggag
      181 ttcatcgagg gagaagtcag cgcccagctc cgaggttgga gcagccccgc cgggcaactt
      241 gaatttctgc aaacgaacac agcaccggga gctctgcaga cctgtgtcgg cgcggaaccc
      301 ggactgagac atgccttttg aacttctcag atagaggaac cccagtgaag actgatcagt
      361 tcttacaatt ctcaaagcat ggcccataaa tatgtgggtt tgcagtatca cggatcagtg
      421 acatttgagg atgtggccat agccttctcc cagcaggagt gggagagtct ggactcttcc
      481 cagaggggct tgtacagaga tgtgatgttg gagaactaca ggaacttggt gtcaatggga
      541 cattcccgtt ctaaaccaca tgtgatcgcc ttattggaac aatggaaaga gcctgaagtg
      601 acagtgagga aagatggaag aagatggtgc acagatttgc agttggaaga tgatacaatc
      661 ggctgtaaag aaatgcccac ctctgaaaac tgtccatctt ttgctctaca tcagaaaata
      721 agtagacaga aaccacgtga atgtcaggaa tatggaaaga ccctttgtca agactcaaag
      781 cctgttcaac atgaaagaat acatagtagt gaaaaaccca acagatgtaa agaatgtggg
      841 aagaacttta gtaatggaca tcaactcacc atacatcaga gattgcatgt tggtgagaaa
      901 ccctataaat atgaaaaatg tgggaaggcc tttatcagtg gctcagcctt tgttaagcat
      961 gggagaattc acactggtga gaagccactc aaatgtaagc aatgtggaaa gactattagt
     1021 ggtagctatc aacttacagt acataagagt attcatactg ggaagaaacc atatgagtgc
     1081 ggggaatgtg ggaaagcttt tctagtatat ggaaagctta cccggcatca gagtactcac
     1141 actggtgaaa aaccctttgg gtgtgaggag tgtgggaagg ccttcagtac cttttcatac
     1201 ctggttcaac atcagcgaat tcataccagt gaaaaacctt acgaatgcaa agaatgtggg
     1261 aaggccttta gcactagctc accccttgct aagcatcaga gaattcatac tggcgagaaa
     1321 ccctatgaat gtaaggagtg tgggaagtcc ttcactgtgt atggacagct tactcgacat
     1381 cagagtattc atactggtga gaaacctttt gaatgtaagg aatgtggaaa ggcctttaga
     1441 cttagttcct tccttcatgc acatcagcga attcatgcag agataaagcc ctacggatgc
     1501 aaggaatgcg ggagaacctt cagtcgtgcc tcatatcttg ttcaacatgg aagacttcac
     1561 actggcgaga agccctatga atgtaaggag tgtggcaagg cctttagtac tggctcatac
     1621 cttgttcagc atcagaggat ccatactggg gagaaaccct atgaatgtaa ggaatgtggc
     1681 aaagccttta ttagtcgcca tcagcttacc gtacatcaaa gggttcatac tggagagaaa
     1741 ccctatgagt gtaaggaatg tggcaaggcc ttcagagtgc acgtacatct cacacagcat
     1801 cggaaaattc atactgatgt aaagccctat gaatgtaagg aatgtggaaa gacttttagt
     1861 cgagcctcgt accttgtaca acatagcaga atccatactg gtaagaagcc ctatgagtgt
     1921 aaggagtgtg gcaaggcctt cagttctggc tcataccttg ttcagcatca aagaattcat
     1981 actggggaga aaccctatga atgtaacaaa tgtgggaaag cctttactgt ttatggacaa
     2041 cttattggac atcagagtgt tcacactggt gagaaacctt ttgaatgtaa ggaatgcggg
     2101 aaggccttta gacttaattc attccttact gaacatcagc gggtacacac tggtgagaaa
     2161 ccctttaaat gcaaaaaatg tgggaagacc tttagataca gttcagccct taaagtgcat
     2221 ctgagaaaac atatgagtgt tataccctaa gagtctgagg agtgtgggaa gtgcttcgtg
     2281 tgtggctcaa acattgttga acatcgggga atttatgctg gtaggaaact ttcaaatgtg
     2341 aagaatattg gcaggtctat tctcatctta taattcataa tataactcag aaaacataag
     2401 aatattcctt tgtcatttat aggtttgtaa taccaatatt tatactggtg gaccattcag
     2461 aaaaagtggg aaacgttatt acttaatggt tacagcactg acagcatgaa cttttatatg
     2521 atgcatttat tctaatgtga ttgtatgaac aagtgaataa aaaaccttgg acctcctaaa
//
