LOCUS       NM_001037813            4336 bp    mRNA    linear   PRI 04-APR-2024
DEFINITION  Homo sapiens zinc finger protein 284 (ZNF284), mRNA.
ACCESSION   NM_001037813 XM_496317
VERSION     NM_001037813.4
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 4336)
  AUTHORS   Yin,G., Ji,C., Zeng,L., Wang,Z., Wang,J., Shen,Z., Wu,T., Gu,S.,
            Xie,Y. and Mao,Y.
  TITLE     Cloning and characterization of a novel KRAB-domain-containing zinc
            finger gene (ZNF284L)
  JOURNAL   Mol Biol Rep 33 (2), 137-144 (2006)
   PUBMED   16817023
  REMARK    GeneRIF: This study reports the cloning and characterization of a
            novel human zinc finger protein cDNA (ZNF284L) from fetal brain
            cDNA library. The ZNF284L cDNA is 2223 bp in length encoding a
            593-aa polypeptide.
REFERENCE   2  (bases 1 to 4336)
  AUTHORS   Shannon,M., Hamilton,A.T., Gordon,L., Branscomb,E. and Stubbs,L.
  TITLE     Differential expansion of zinc-finger transcription factor loci in
            homologous human and mouse gene clusters
  JOURNAL   Genome Res 13 (6A), 1097-1110 (2003)
   PUBMED   12743021
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AY458845.1, AC084219.2 and BM989725.1.
            
            On Nov 22, 2018 this sequence version replaced NM_001037813.3.
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: CR936662.1, SRR1660807.189887.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA1965299, SAMEA1966682
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000421176.4/ ENSP00000411032.2
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-2193              AY458845.1         16-2208
            2194-3860           AC084219.2         21401-23067
            3861-4336           BM989725.1         18-493              c
FEATURES             Location/Qualifiers
     source          1..4336
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="19"
                     /map="19q13.31"
     gene            1..4336
                     /gene="ZNF284"
                     /gene_synonym="ZNF284L"
                     /note="zinc finger protein 284"
                     /db_xref="GeneID:342909"
                     /db_xref="HGNC:HGNC:13078"
     exon            1..133
                     /gene="ZNF284"
                     /gene_synonym="ZNF284L"
                     /inference="alignment:Splign:2.1.0"
     exon            134..216
                     /gene="ZNF284"
                     /gene_synonym="ZNF284L"
                     /inference="alignment:Splign:2.1.0"
     CDS             202..1983
                     /gene="ZNF284"
                     /gene_synonym="ZNF284L"
                     /codon_start=1
                     /product="zinc finger protein 284"
                     /protein_id="NP_001032902.1"
                     /db_xref="CCDS:CCDS46099.1"
                     /db_xref="GeneID:342909"
                     /db_xref="HGNC:HGNC:13078"
                     /translation="MTMFKEAVTFKDVAVVFTEEELGLLDVSQRKLYRDVMLENFRNL
                     LSVGHQLSHRDTFHFQREEKFWIMETATQREGNSGGKIQTELESVPETGPHEEWSCQQ
                     IWEQTASELTRPQDSISSSQFSTQGDVPSQVDAGLSIIHIGETPSEHGKCKKFFSDVS
                     ILDLHQQLHSGKISHTCNEYRKRFCYSSALCLHQKVHMGEKRYKCDVCSKAFSQNSQL
                     QTHQRIHTGEKPFKCEQCGKSFSRRSGMYVHCKLHTGEKPHICEECGKAFIHNSQLRE
                     HQRIHTGEKPFKCYICGKSFHSRSNLNRHSMVHMQEKSFRCDTCSNSFGQRSALNSHC
                     MDHTKEKLYKCEECGRSFTCRQDLCKHQMDHTGDKPYNCNVCGKGFRWSSCLSRHQRV
                     HNGETTFKCDGCGKRFYMNSQGHSHQRAYREEELYKCQKCGKGYISKFNLDLHQRVHT
                     GERPYNCKECGKSFRWASGILRHKRLHTGEKPFKCEECGKRFTENSKLRFHQRIHTGE
                     KPYKCEECGKGFRWASTHLTHQRLHSREKLFQCEDCGKSSEHSSCLQDQQSDHSGEKT
                     SKCEDCGKRYERRLNLDMILSLFLNDI"
     exon            217..343
                     /gene="ZNF284"
                     /gene_synonym="ZNF284L"
                     /inference="alignment:Splign:2.1.0"
     exon            344..436
                     /gene="ZNF284"
                     /gene_synonym="ZNF284L"
                     /inference="alignment:Splign:2.1.0"
     exon            437..4336
                     /gene="ZNF284"
                     /gene_synonym="ZNF284L"
                     /inference="alignment:Splign:2.1.0"
     regulatory      4313..4318
                     /regulatory_class="polyA_signal_sequence"
                     /gene="ZNF284"
                     /gene_synonym="ZNF284L"
                     /note="hexamer: AATAAA"
     polyA_site      4336
                     /gene="ZNF284"
                     /gene_synonym="ZNF284L"
                     /note="major polyA site"
ORIGIN      
        1 gcagtgcatt cggtggtagt ttggtgtcag tcctgtgtct tgtcggtcct tctaaacgtg
       61 tccccttacg atgctggctc gcaaccacct ggaagttgac taaggggaga aggagtctcg
      121 ttggaaaacg gaggcacaat tctgtcttct cttgaactgc ataactgaga actctgcaaa
      181 ttccccaaag aaggaggaaa aatgaccatg ttcaaggagg cagtgacctt caaggatgtg
      241 gctgtggtct tcaccgagga ggagctgggg ctgctggacg tttcccagag gaagctgtat
      301 cgagatgtca tgctggagaa cttcagaaac ctgctatcag tggggcatca actttcccac
      361 cgagatactt ttcacttcca aagagaagaa aagttttgga tcatggagac agcaacccaa
      421 agagaaggga attcaggagg caagatccaa actgagttgg agtctgttcc agaaacagga
      481 ccacatgaag agtggtcttg ccagcaaatc tgggaacaaa ctgcaagtga gttaactaga
      541 cctcaagact ccataagtag ctctcagttc tccacacaag gtgatgtccc ctcccaggtt
      601 gacgcaggac tatctataat tcacatagga gagacacctt ctgagcatgg gaagtgtaaa
      661 aaattcttca gtgatgtctc catccttgat cttcatcaac aattacactc aggaaagata
      721 tcccatacat gtaatgagta caggaagaga ttctgttata gctcagctct ttgtcttcat
      781 cagaaagttc acatgggaga gaaacgctat aagtgtgatg tgtgtagtaa ggcatttagt
      841 cagaactcac aactgcaaac tcatcagaga atccacactg gagagaaacc attcaaatgt
      901 gagcagtgtg ggaaaagttt cagccgtaga tcaggaatgt atgttcattg caaattacac
      961 acaggagaaa aacctcatat ttgtgaggaa tgtgggaagg ccttcattca caattcccag
     1021 cttcgggaac atcaaagaat ccatactggg gagaagccat tcaaatgtta tatatgtggt
     1081 aagagcttcc atagtagatc aaatcttaat aggcattcca tggtccacat gcaagagaaa
     1141 tcatttagat gtgatacctg tagtaatagc tttggtcaga gatcagcact taatagtcat
     1201 tgcatggacc acacaaaaga gaaactatac aaatgtgaag aatgtggaag gagcttcact
     1261 tgtaggcaag atctttgtaa gcatcagatg gaccatacag gagacaaacc atataattgt
     1321 aatgtatgtg ggaagggctt caggtggtcc tcatgtcttt caagacatca gcgggtccac
     1381 aatggagaaa caacattcaa gtgcgacgga tgtgggaaga gattttatat gaattcacag
     1441 ggccattcac atcagagagc ctatagagaa gaagaactgt ataaatgtca gaagtgtggg
     1501 aagggctaca ttagtaagtt taatcttgac ttgcaccaga gggtccacac gggagagaga
     1561 ccttataatt gtaaggaatg tggaaagagc ttcaggtggg cctcaggtat tttgagacat
     1621 aagagactcc atactggaga aaaaccattc aaatgtgaag agtgtgggaa gaggtttact
     1681 gagaattcaa aacttcgttt ccatcaaaga attcacactg gagaaaagcc ttacaaatgt
     1741 gaggagtgtg gaaagggatt cagatgggcc tcaactcatc taacccatca aagactccac
     1801 agcagagaaa aactattcca atgtgaggat tgtgggaaga gcagtgagca cagttcatgc
     1861 cttcaagacc aacaaagcga ccacagtgga gaaaaaacat ccaaatgtga ggactgtggg
     1921 aagcgctacg agaggcgctt gaatctagat atgattttat cattattttt aaatgatata
     1981 taattattgt ccatatttat gggttacagc atatttcaat acatgtatac aatgtataat
     2041 gatcaaatca gtgttattag catatccatc acctccttta tcatttattt gtggatcatt
     2101 tatcatttct ttgtgctttg aacgttcaaa aactgctgtt ctagttattt gaaaataagt
     2161 tattattaat tatagtcacc tttagtgctg tggaacacta gaacttgttc ctttcatcat
     2221 cttactgtac tttcatatct gttaacgaat ctttcatcat ccaccctctc tcctactttt
     2281 cccttctagt aattgctatg ccatgctgct tctgcttttt tttttttttt tttttttttt
     2341 tgagaacaga gtcttccagg cttgagtgta gtggcatgat cctttctcac tgcagcctcc
     2401 acctcctggg ttcaagcgat tctcctgcct aaacctcctg agtagcaggg attacaggca
     2461 cgcaccacca cgcccagcta atttttgtac tttttttttt ttttttttga gacagagtat
     2521 cgctctgtcg cccagtatgg agtgcaatgg cttgatctcg gctcactgca acctctgcct
     2581 cctgggttca aacgattctt ccctgccttg gcctcccgag tagctgggac tacaggcgcc
     2641 cgccaccaca cctgactaat tgttgtatgc gtagtagaga tggggttttg ccatattggc
     2701 caacctggac ttgaactcct gacttcagat gatccgccca cctcggcctc ccaaagtgct
     2761 gggattacag gcgtgagcca ccatgcccac catgcctaaa aatttttgta tttttagtga
     2821 agatggggtt tcaccacatt ggccaggcta gccttgaact cccaaactca aatggtccac
     2881 ctgccttggc ctcccaaagt gctgggatta caggcatgag ccaccgtgcc cagccaatgc
     2941 tatgctgctt ctatgatgtc aactttttag cttccacata tgtgtgaaaa catgtggtat
     3001 ttatctttct gggcctgaat ttacatcact caacatcatg ttctccaaag cttatcttta
     3061 tcttgccata aatgacagaa ttttattatt ttttatggtt aaatagtgta cctttgtgta
     3121 tgtatgccac attttcttta ccattttctg ttgatgaaca cttagattgg ttccatatgt
     3181 tagctattgc aaatagtact ataataaata taggagtgca gataggagtt caacacactg
     3241 atttcctttc ctttggatat acagctagta gtgggattgc tggatcactt gaatgctgat
     3301 atgcataaga ggatctacac tggagaaaaa ccatggaagt gtggagattg tggtacatgc
     3361 ttcagtcagg gctcacatct tcaaattcag tgtctgttct gtagagaaac cttaataatg
     3421 tgatatatgt gacagcaaag agttataaga tatgaatatg ttaattttag tagatacttc
     3481 cgaaaagtat ttcaaactgg ttgtaccact ataaactctg accattatta ggcaagaatt
     3541 ggcttttttt ttttttttct tttgagacag tcttgctctg tcacccagac tggcatgcag
     3601 tggaatgatc acggctccct gcagccttga cctcccaggc tcaagaaatc cttctgcctc
     3661 agcccctcaa aagctgggac tataggcatg caacaacacg cctggctaaa tttttgttgt
     3721 agagatgggg tctcactatg ttgcccaaat tggtctcaaa ctcctgggct caagcgattc
     3781 tccctcctca gccttccaaa gtgctgggat tacaggcctg agccatgcgc acagcatttt
     3841 gttttgtttt gttttgtttt tgagatgggg tctctcggtg ttgcccaggc tggattgctt
     3901 attcacagat gcagttacag tgccctatag cctcgaactc ctgggcctaa gtgatcctct
     3961 tgcttcaatc ccctgagaag ctgggactac aggcatggac caccacccct gattgatctt
     4021 ctttagtttc tataacaaaa tagtacactg tttccacaaa cttgggaagg ctagtatttg
     4081 ggggtggggg gcgtggaaat cactaaacaa caaagaaaat ctgatgaatt ggacagcata
     4141 aaaatattgg cataaagatg aacataacat aagcaggaat atttaaagca catacttttt
     4201 atagagtgtc tcccctgtaa tgtctctggt taaatgaaag ggtttcaaat gtgaagacaa
     4261 ccctaaccat actcattatc tgtaaaagat gtagcattgt catggactcc ttaataaacg
     4321 tgaagacttt aatcca
//
