LOCUS       NM_001367757            6420 bp    mRNA    linear   PRI 04-APR-2024
DEFINITION  Homo sapiens zinc finger protein 275 (ZNF275), transcript variant
            1, mRNA.
ACCESSION   NM_001367757
VERSION     NM_001367757.1
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 6420)
  AUTHORS   Luck,K., Kim,D.K., Lambourne,L., Spirohn,K., Begg,B.E., Bian,W.,
            Brignall,R., Cafarelli,T., Campos-Laborie,F.J., Charloteaux,B.,
            Choi,D., Cote,A.G., Daley,M., Deimling,S., Desbuleux,A., Dricot,A.,
            Gebbia,M., Hardy,M.F., Kishore,N., Knapp,J.J., Kovacs,I.A.,
            Lemmens,I., Mee,M.W., Mellor,J.C., Pollis,C., Pons,C.,
            Richardson,A.D., Schlabach,S., Teeking,B., Yadav,A., Babor,M.,
            Balcha,D., Basha,O., Bowman-Colin,C., Chin,S.F., Choi,S.G.,
            Colabella,C., Coppin,G., D'Amata,C., De Ridder,D., De Rouck,S.,
            Duran-Frigola,M., Ennajdaoui,H., Goebels,F., Goehring,L., Gopal,A.,
            Haddad,G., Hatchi,E., Helmy,M., Jacob,Y., Kassa,Y., Landini,S.,
            Li,R., van Lieshout,N., MacWilliams,A., Markey,D., Paulson,J.N.,
            Rangarajan,S., Rasla,J., Rayhan,A., Rolland,T., San-Miguel,A.,
            Shen,Y., Sheykhkarimli,D., Sheynkman,G.M., Simonovsky,E., Tasan,M.,
            Tejeda,A., Tropepe,V., Twizere,J.C., Wang,Y., Weatheritt,R.J.,
            Weile,J., Xia,Y., Yang,X., Yeger-Lotem,E., Zhong,Q., Aloy,P.,
            Bader,G.D., De Las Rivas,J., Gaudet,S., Hao,T., Rak,J.,
            Tavernier,J., Hill,D.E., Vidal,M., Roth,F.P. and Calderwood,M.A.
  TITLE     A reference map of the human binary protein interactome
  JOURNAL   Nature 580 (7803), 402-408 (2020)
   PUBMED   32296183
REFERENCE   2  (bases 1 to 6420)
  AUTHORS   Mallon,A.M., Platzer,M., Bate,R., Gloeckner,G., Botcherby,M.R.,
            Nordsiek,G., Strivens,M.A., Kioschis,P., Dangel,A., Cunningham,D.,
            Straw,R.N., Weston,P., Gilbert,M., Fernando,S., Goodall,K.,
            Hunter,G., Greystrong,J.S., Clarke,D., Kimberley,C., Goerdes,M.,
            Blechschmidt,K., Rump,A., Hinzmann,B., Mundy,C.R., Miller,W.,
            Poustka,A., Herman,G.E., Rhodes,M., Denny,P., Rosenthal,A. and
            Brown,S.D.
  TITLE     Comparative genome sequence analysis of the Bpa/Str region in mouse
            and Man
  JOURNAL   Genome Res 10 (6), 758-775 (2000)
   PUBMED   10854409
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            HY052974.1, BX280482.1, DA249563.1, AC152008.1 and AC152007.1.
            This sequence is a reference standard in the RefSeqGene project.
            
            Summary: This gene encodes a zinc finger protein that appears to be
            conserved in eutheria. Its function has not yet been established.
            [provided by RefSeq, Jul 2010].
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR1803612.262228.1,
                                           SRR1803614.94867.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA1965299, SAMEA1966682
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000650114.2/ ENSP00000496975.2
            RefSeq Select criteria :: based on manual assertion, conservation,
                                      expression, longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-451               HY052974.1         2-452
            452-738             BX280482.1         196-482
            739-877             DA249563.1         435-573
            878-2680            AC152008.1         33982-35784
            2681-6420           AC152007.1         21403-25142
FEATURES             Location/Qualifiers
     source          1..6420
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="X"
                     /map="Xq28"
     gene            1..6420
                     /gene="ZNF275"
                     /note="zinc finger protein 275"
                     /db_xref="GeneID:10838"
                     /db_xref="HGNC:HGNC:13069"
     exon            1..133
                     /gene="ZNF275"
                     /inference="alignment:Splign:2.1.0"
     exon            134..210
                     /gene="ZNF275"
                     /inference="alignment:Splign:2.1.0"
     CDS             180..1469
                     /gene="ZNF275"
                     /note="isoform 1 is encoded by transcript variant 1"
                     /codon_start=1
                     /product="zinc finger protein 275 isoform 1"
                     /protein_id="NP_001354686.1"
                     /db_xref="CCDS:CCDS94693.1"
                     /db_xref="GeneID:10838"
                     /db_xref="HGNC:HGNC:13069"
                     /translation="MMSHPCVSLLGVPVLNPALVPHLAQGQVLLVSDPSPNTDPAKYS
                     ESTSATRHQMKGEDAQPQEMASTSFPRASGPSPEFRQHGDSDGKRGSPQNLPIEHHFA
                     CKECGDTFRLKVLLVQHQRVHSEEKGWECGDCGKVFRGVAEFNEHRKSHVAAEPQPGP
                     SRALENAAEKREQMEREAKPFECEECGKRFKKNAGLSQHLRVHSREKPFDCEECGRSF
                     KVNTHLFRHQKLHTSEKPFACKACSRDFLDRQELLKHQRMHTGHLPFDCDDCGKSFRG
                     VNGLAEHQRIHSGAKPYGCPHCGKLFRRSSELTKHRRIHTGEKPYACGQCGKAFRQSS
                     SLLEHARIHSGERPYACGECGKAFRGPSDLIKHRRIHSGLKPYECDKCGKAFRRSSGL
                     SRHRRIHSGARRCECSQCGRVFKRRSALQKHQPTHHE"
     exon            211..312
                     /gene="ZNF275"
                     /inference="alignment:Splign:2.1.0"
     exon            313..6420
                     /gene="ZNF275"
                     /inference="alignment:Splign:2.1.0"
     regulatory      6399..6404
                     /regulatory_class="polyA_signal_sequence"
                     /gene="ZNF275"
                     /note="hexamer: AATAAA"
     polyA_site      6420
                     /gene="ZNF275"
                     /note="major polyA site"
ORIGIN      
        1 ggaaacgcgc cgcggggctg ttagctcggc tgggcacggg cggctccgtg gcgcttcctg
       61 ccacgccagg cctgcctggg ccgcgccagc gccgctccac cgagggccgc gcgtcggccg
      121 ccgccgggcc tggatggggc cttacctgcc aggctgatcc cttggagtag ttctgaggca
      181 tgatgagtca tccgtgtgtg tctcttttgg gcgttcctgt tttaaatcct gccttggtcc
      241 ctcacctggc acaaggacaa gtgctactgg tgtcagaccc atcgcccaac actgatcctg
      301 ctaagtactc tgaaagcacc tccgcgaccc gacaccagat gaagggggaa gatgcccagc
      361 cacaggagat ggcgtccaca agcttcccaa gggccagtgg tcccagtcct gaattcagac
      421 agcacgggga ctctgacggg aagagaggga gcccacagaa tctgcccata gaacatcatt
      481 ttgcttgtaa agagtgtggg gacacctttc ggcttaaagt cctgcttgtc cagcaccaga
      541 gagtccacag tgaggagaag ggctgggaat gtggcgactg cgggaaggtc tttagggggg
      601 tggcggagtt taatgagcac aggaaaagcc acgtagctgc ggagccccag cccggcccca
      661 gtagggccct ggagaatgcc gcggagaaga gggagcagat ggagagggag gcaaagccct
      721 tcgagtgcga ggagtgcgga aaacggttta agaagaatgc aggcctgagt cagcatctga
      781 gggtccacag cagagagaag ccctttgatt gcgaggaatg cgggcggtcg ttcaaagtca
      841 acacccacct cttccgacat cagaaacttc acacttcgga aaagcctttc gcctgcaagg
      901 cgtgcagcag ggatttcctg gatcgccagg agcttctcaa gcaccagcgc atgcacactg
      961 gccacctgcc cttcgactgc gacgactgcg gcaagtcctt ccgaggggtc aacgggctgg
     1021 ccgagcacca gcgcatccac agtggggcca agccatacgg gtgtccccac tgcggcaagc
     1081 tcttccgaag gagctcggag ctcaccaagc accggcggat ccacacgggc gagaagccct
     1141 acgcctgcgg ccagtgcggc aaggccttcc gccagagctc cagcctcctg gagcacgcac
     1201 gcatccacag tggcgagcgg ccctacgcat gcggcgagtg tggcaaggcc ttccgtgggc
     1261 cctctgacct catcaagcac cggcgcatcc acagcggact gaaaccctat gagtgcgaca
     1321 aatgcggcaa ggccttccgc cggagctccg gcctcagtcg ccaccggcgg atccacagtg
     1381 gggcgcggcg ctgcgaatgc agccagtgtg gccgcgtgtt caagaggcgc tcggcactgc
     1441 agaagcatca gccaacccac cacgagtaga aacgccctgt ggtcccgcgg gacagggacg
     1501 gagtccccag aggggatggc agagtcaaag gagatgaaca gttttgtagc gcttatatat
     1561 tttgtcttcc aaaaggttga gaccgattta tactgccacc agcaatttat aagtgttacg
     1621 ttatgcccat caagagtagc ttgtaccatt taacttagtt tggctagttt aactggtagg
     1681 aagtaccatc aaggtatttc agtccacatg ccttgaatcc aagaatgaga gaggacaaat
     1741 ctggatgtgg ggtagggagg ggcttagagg tcatcaactc caagctcccc ccgccccaga
     1801 gaaacacaca gagctgttcc acgatggcgt cctcataatg tgatcccagc tttcctgaag
     1861 agaacgttgc cctcatgatt tttggcctac ttgaatttat aaatttttag ggatgtaaat
     1921 agaacactca aatgtcttaa aatatttaat ttattaattt agttatacat acatactgta
     1981 aatcacatat tatataaaat aatatattaa tttagaaaat accccatttt tgccaccctc
     2041 cctttcacga aatcatttta ctctgactcc tcaccgtctt caccaacatg ggaaccctgt
     2101 ttgagtcatc agacagtttc aagacacacc cagtcacttc catccgagct ctgcacggtc
     2161 gctcagtgac gatcccttca tgaggctctc attagaaatt ttctcccaag ccataagacc
     2221 atatttgcag aacattagga cgatttctct tgtcgttttt taatctgtcc tgtgactgta
     2281 caatataacc acttaaggtc atactttttc aaacaacctt taaacgtctt ttcttttaaa
     2341 gcacccaaaa tgtcattgtg aggccaaacg cctagtaaca gttactgaat ctgggttaaa
     2401 tgtcggtatc tttttttctt aaaccatttc aatttggtgt cccctataca tatccaaaac
     2461 tagcatcgat tggggttgtt ttgaactaat gggtcttgtc ctcaagcagc actattttgt
     2521 tcaaaataaa atagttgaga gcatgcccct aagaagagat acatctcaag gactcaagtg
     2581 cagggtgacg cctccttttg gaaatgagcc tctcctggta tcaggcctag atggtacttc
     2641 tccagccttc cgtttcttgt tctataaaac aggggtgatc acagcaccta cctccgaagg
     2701 ttatcacgag gactgccatc gtggctgcag agtgccagga ccaccggcct ggtatggagg
     2761 tacacactca gtgaaggcca tctgctgtca ttgtcattgt catagttatt gccgtcattc
     2821 tgtggcttgt caattccaga actggggata gaccccaggc ctcctgacca ccagtctcat
     2881 ctttctctta tgcgatgact taaatggtgt ttctgttttt tgcatgcaaa tggtccgttc
     2941 atctcctttg actagttatc aacttacctt cggatatatt aactttatgt agcagttctt
     3001 tctatattga tggtgatgtt ctcttttcca attttattgc tttgcttttt gtagcagttt
     3061 tattacgttt ttgttgtgaa agcttttaat ttttacatat ccaagcattc attttttgtc
     3121 cactcagtca taactttcat tgcttctgta gctagatatg atgacatttt ctctagaatt
     3181 ttaattacaa acaaaaagct gcaaccccag cccatcagaa ggtgagtaca ccaggtgggc
     3241 aggctggatg gaaatgggcc agagaagcag gctctttcct catccgagat gcggactccc
     3301 tgtctatctg tgggcaccac ttgactatcc aacctgacca ctgcggcaca ctggagatgc
     3361 tcccatcata gattagccag aactctgtga ctgctcatca ttatagaccc cgccagcagc
     3421 agtggggctt ggcctcacct agatcaatgg agtggtccaa acttggtctg ggagcaagca
     3481 gcccagccat cctttgagct cctgggagcc ttggcaatgc tccgagtgga ttcagtgact
     3541 gagcagcaga ttcacccaag aaacatctcc ttggacacaa gaagacttgc ctagaccaca
     3601 tcctcctttc agccggtgac tctagaacta gaaagagatt ggttcatagg cttctgctgt
     3661 gggcagctag gggaaaattc acccatgtgt tctggcatca cttcctatag ccacacctaa
     3721 gtgagggcaa cagagcagag gctcggagag gaaccctgcc cctccgatgg cttgtgcgtt
     3781 atgctgatag aagctggcag cactgccctg ggctatgatt tgcaacagcc atgcccagga
     3841 ggagcactaa agcaaaggtt tggagggcag tggaaccctt ctgaaagcct gtgtggcata
     3901 gaagtagaag ctggtcctcc tgggtctgag ctaccatttc cagtgggctc ccccaagagg
     3961 aacagcagca agggctagcg aggaacctgc ccctccagtg gcccacagaa gccacagata
     4021 gaagccagcc ccaccagggc tgtgctgtga cttcccagca gctgtggctg gggacaggga
     4081 cactaggagg gcctggcaag gaagtgtgcc cttctcgtgg gcccaccaag gctgaggcag
     4141 agcttcctag cagacacaac ttggaagggc ttctcaggca cccatcctga cccccaggct
     4201 ggagaggagc caaaagcact tgttacatag tgattccttt tgccctgtgg gcctcagttc
     4261 ttgcagtagt tgtgaatctg tgtctgaaat cactactttc ttctcggatc ctttttctct
     4321 tttcgagttg ttaggatgtg ttttgtacag ctgtcatttg ataaagaagg ttgacctcta
     4381 ccaggggcaa gtctggcacc tttacctaga agtactctgc catgtcttgc ccgttcattt
     4441 atcgtttgtt gggtttcatg agggatccca ttgaagtaga tcccttttat gaagggatcc
     4501 cattgaatgc agcattaact cagaacgtag cataaagtcg tcactgctcc cagctgggac
     4561 gtggtgtctt ggcatccctt cctgccgtcc ttgactcttt cccatcttca gttctataat
     4621 tttctcccaa acaaatgctc ttttagagtt aacactaaag atctggtctt tgccgtcaag
     4681 gttgacagaa cagctgttca tggtgtttgc ggtgaaaccc gtgttctctt tcaatgcagt
     4741 ctgtggcttt aacgtgtgtc ctgtaatttc gccaagatca tttcttgcct ctggtaactt
     4801 gggggtggat ttccttgggc tctctaggtg tactgctatg tcagatgcaa aatgtcaccc
     4861 agcttcctgt cacatatcct tgtctgtgca ttcatgcatc tacctcattc cggttttctt
     4921 tctaatctca tgtattcctg ttgtgaggaa atgtgttctt ttcccgatcc ttttgtagtt
     4981 catacacatg acaattgggt ttccacgcac gtgcatgaga tgttcctcct tcaaaccttg
     5041 ttactatgtc agcacattaa ctgcctggca tggaaaaaga aaaaaaaaaa agaaatatgt
     5101 tcttttccta ccatttgaaa aaaatcctcc attgctttta ttagagtttt gaatacttgt
     5161 gaaaattttc aaaagaaagt aattgattac catttttgct gcttattacg atgagctgtg
     5221 tccattagct gtgtcacccc actcttgcat ttccagaata gtccctaccc aattgcagcg
     5281 ggcatgtttt tgagtggtgt tgcattccat gtgcttgatt ttgtcctaga actggcacag
     5341 cgcctgccct acctgcagcc ctgggttgtg gccctgttgc gtaccatgtg atttgccacc
     5401 ccgcttctag gccatattaa ttcagccaga actgaacacc tgacccaagg gcagcaagca
     5461 atcatcagag catagagctg acagaacatg atggaccacg gacaccacca ggccttccag
     5521 atctgaaatg caaacaagga aacagaagct tctaggcatc agaaggtgtg gggagcagca
     5581 cagtactcag aggagtgagg agcgtggcgc ctgctgggag gaaggcctgg ccatggtatg
     5641 ttcttggatt tctggcagca gccctcattg gtccacgtgc gtccccacta cagactcctt
     5701 gacttgagcc agcttgagtg ggtctctact cttttctatt gtgttttgcc acttggctgc
     5761 ttcctggcca agtcgcacct gactgcatga acacctgttc aaacgtgtgt tctctgttct
     5821 ctaagatggg tgaaagtcga tgccttctag tctcagtgaa tttaacctgt gattttatgt
     5881 ctacgtatat tgttccttta ctgaacccac cacatgcggg ccataaaatg agtgaaatca
     5941 cagtgcaccc tgttctctta tttttgaagt gtttcacgat ttccagcatg tccatcagat
     6001 ggggggattg ctaacttctc tcttactcat gtacttacat tctgtagttc tcattgcatc
     6061 actttggatg tttactttga aaagcagaaa ctgtctcttt aaacttggcc ctcaatgtca
     6121 tttgcgtatc tctgagaaca atagctatgt cccaccccag tttgtatttc cgttggttgt
     6181 tggcactttt ttctcattcc cccatctcat taccttgtct gttttctggc actcactata
     6241 atcagccttg cactagagct gtttgtggac ttggcttcac cccctcctcc tcagccctcc
     6301 cccacccatt aaattgtgag ctcttagaag acaggggtgg cctttcatgt ctgatcccct
     6361 accaaatcta gcacagtgcc ttgcatcaag tagatttcaa taaatatatg ttaaatggca
//
