LOCUS       NM_003417              12163 bp    mRNA    linear   PRI 20-SEP-2024
DEFINITION  Homo sapiens zinc finger protein 264 (ZNF264), mRNA.
ACCESSION   NM_003417 XM_375660
VERSION     NM_003417.5
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 12163)
  AUTHORS   Huttlin,E.L., Bruckner,R.J., Navarrete-Perea,J., Cannon,J.R.,
            Baltier,K., Gebreab,F., Gygi,M.P., Thornock,A., Zarraga,G., Tam,S.,
            Szpyt,J., Gassaway,B.M., Panov,A., Parzen,H., Fu,S., Golbazi,A.,
            Maenpaa,E., Stricker,K., Guha Thakurta,S., Zhang,T., Rad,R.,
            Pan,J., Nusinow,D.P., Paulo,J.A., Schweppe,D.K., Vaites,L.P.,
            Harper,J.W. and Gygi,S.P.
  TITLE     Dual proteome-scale networks reveal cell-specific remodeling of the
            human interactome
  JOURNAL   Cell 184 (11), 3022-3040 (2021)
   PUBMED   33961781
REFERENCE   2  (bases 1 to 12163)
  AUTHORS   Luck,K., Kim,D.K., Lambourne,L., Spirohn,K., Begg,B.E., Bian,W.,
            Brignall,R., Cafarelli,T., Campos-Laborie,F.J., Charloteaux,B.,
            Choi,D., Cote,A.G., Daley,M., Deimling,S., Desbuleux,A., Dricot,A.,
            Gebbia,M., Hardy,M.F., Kishore,N., Knapp,J.J., Kovacs,I.A.,
            Lemmens,I., Mee,M.W., Mellor,J.C., Pollis,C., Pons,C.,
            Richardson,A.D., Schlabach,S., Teeking,B., Yadav,A., Babor,M.,
            Balcha,D., Basha,O., Bowman-Colin,C., Chin,S.F., Choi,S.G.,
            Colabella,C., Coppin,G., D'Amata,C., De Ridder,D., De Rouck,S.,
            Duran-Frigola,M., Ennajdaoui,H., Goebels,F., Goehring,L., Gopal,A.,
            Haddad,G., Hatchi,E., Helmy,M., Jacob,Y., Kassa,Y., Landini,S.,
            Li,R., van Lieshout,N., MacWilliams,A., Markey,D., Paulson,J.N.,
            Rangarajan,S., Rasla,J., Rayhan,A., Rolland,T., San-Miguel,A.,
            Shen,Y., Sheykhkarimli,D., Sheynkman,G.M., Simonovsky,E., Tasan,M.,
            Tejeda,A., Tropepe,V., Twizere,J.C., Wang,Y., Weatheritt,R.J.,
            Weile,J., Xia,Y., Yang,X., Yeger-Lotem,E., Zhong,Q., Aloy,P.,
            Bader,G.D., De Las Rivas,J., Gaudet,S., Hao,T., Rak,J.,
            Tavernier,J., Hill,D.E., Vidal,M., Roth,F.P. and Calderwood,M.A.
  TITLE     A reference map of the human binary protein interactome
  JOURNAL   Nature 580 (7803), 402-408 (2020)
   PUBMED   32296183
REFERENCE   3  (bases 1 to 12163)
  AUTHORS   Huttlin,E.L., Bruckner,R.J., Paulo,J.A., Cannon,J.R., Ting,L.,
            Baltier,K., Colby,G., Gebreab,F., Gygi,M.P., Parzen,H., Szpyt,J.,
            Tam,S., Zarraga,G., Pontano-Vaites,L., Swarup,S., White,A.E.,
            Schweppe,D.K., Rad,R., Erickson,B.K., Obar,R.A., Guruharsha,K.G.,
            Li,K., Artavanis-Tsakonas,S., Gygi,S.P. and Harper,J.W.
  TITLE     Architecture of the human interactome defines protein communities
            and disease networks
  JOURNAL   Nature 545 (7655), 505-509 (2017)
   PUBMED   28514442
REFERENCE   4  (bases 1 to 12163)
  AUTHORS   Dolmans,G.H., Werker,P.M., Hennies,H.C., Furniss,D., Festen,E.A.,
            Franke,L., Becker,K., van der Vlies,P., Wolffenbuttel,B.H.,
            Tinschert,S., Toliat,M.R., Nothnagel,M., Franke,A., Klopp,N.,
            Wichmann,H.E., Nurnberg,P., Giele,H., Ophoff,R.A. and Wijmenga,C.
  CONSRTM   Dutch Dupuytren Study Group; German Dupuytren Study Group;
            LifeLines Cohort Study; BSSH-GODD Consortium
  TITLE     Wnt signaling and Dupuytren's disease
  JOURNAL   N Engl J Med 365 (4), 307-317 (2011)
   PUBMED   21732829
REFERENCE   5  (bases 1 to 12163)
  AUTHORS   Oh,J.H., Yang,J.O., Hahn,Y., Kim,M.R., Byun,S.S., Jeon,Y.J.,
            Kim,J.M., Song,K.S., Noh,S.M., Kim,S., Yoo,H.S., Kim,Y.S. and
            Kim,N.S.
  TITLE     Transcriptome analysis of human gastric cancer
  JOURNAL   Mamm Genome 16 (12), 942-954 (2005)
   PUBMED   16341674
REFERENCE   6  (bases 1 to 12163)
  AUTHORS   Rush,J., Moritz,A., Lee,K.A., Guo,A., Goss,V.L., Spek,E.J.,
            Zhang,H., Zha,X.M., Polakiewicz,R.D. and Comb,M.J.
  TITLE     Immunoaffinity profiling of tyrosine phosphorylation in cancer
            cells
  JOURNAL   Nat Biotechnol 23 (1), 94-101 (2005)
   PUBMED   15592455
REFERENCE   7  (bases 1 to 12163)
  AUTHORS   Grimwood,J., Gordon,L.A., Olsen,A., Terry,A., Schmutz,J.,
            Lamerdin,J., Hellsten,U., Goodstein,D., Couronne,O.,
            Tran-Gyamfi,M., Aerts,A., Altherr,M., Ashworth,L., Bajorek,E.,
            Black,S., Branscomb,E., Caenepeel,S., Carrano,A., Caoile,C.,
            Chan,Y.M., Christensen,M., Cleland,C.A., Copeland,A., Dalin,E.,
            Dehal,P., Denys,M., Detter,J.C., Escobar,J., Flowers,D.,
            Fotopulos,D., Garcia,C., Georgescu,A.M., Glavina,T., Gomez,M.,
            Gonzales,E., Groza,M., Hammon,N., Hawkins,T., Haydu,L., Ho,I.,
            Huang,W., Israni,S., Jett,J., Kadner,K., Kimball,H., Kobayashi,A.,
            Larionov,V., Leem,S.H., Lopez,F., Lou,Y., Lowry,S., Malfatti,S.,
            Martinez,D., McCready,P., Medina,C., Morgan,J., Nelson,K.,
            Nolan,M., Ovcharenko,I., Pitluck,S., Pollard,M., Popkie,A.P.,
            Predki,P., Quan,G., Ramirez,L., Rash,S., Retterer,J., Rodriguez,A.,
            Rogers,S., Salamov,A., Salazar,A., She,X., Smith,D., Slezak,T.,
            Solovyev,V., Thayer,N., Tice,H., Tsai,M., Ustaszewska,A., Vo,N.,
            Wagner,M., Wheeler,J., Wu,K., Xie,G., Yang,J., Dubchak,I.,
            Furey,T.S., DeJong,P., Dickson,M., Gordon,D., Eichler,E.E.,
            Pennacchio,L.A., Richardson,P., Stubbs,L., Rokhsar,D.S.,
            Myers,R.M., Rubin,E.M. and Lucas,S.M.
  TITLE     The DNA sequence and biology of human chromosome 19
  JOURNAL   Nature 428 (6982), 529-535 (2004)
   PUBMED   15057824
REFERENCE   8  (bases 1 to 12163)
  AUTHORS   Kim,J., Bergmann,A., Wehri,E., Lu,X. and Stubbs,L.
  TITLE     Imprinting and evolution of two Kruppel-type zinc-finger genes,
            ZIM3 and ZNF264, located in the PEG3/USP29 imprinted domain
  JOURNAL   Genomics 77 (1-2), 91-98 (2001)
   PUBMED   11543637
COMMENT     REVIEWED REFSEQ: This record has been curated by NCBI staff. The
            reference sequence was derived from AK292504.1, AB007872.1,
            AC005261.2 and BF063192.1.
            This sequence is a reference standard in the RefSeqGene project.
            
            On Nov 23, 2018 this sequence version replaced NM_003417.4.
            
            Summary: This gene encodes a zinc finger protein and belongs to the
            krueppel C2H2-type zinc-finger protein family. Zinc finger proteins
            are often localized in the nucleus, bind nucleic acids, and
            regulate transcription. [provided by RefSeq, Jan 2010].
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK292504.1, AB007872.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA1965299, SAMEA1966682
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000263095.10/ ENSP00000263095.5
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-2673              AK292504.1         1-2673
            2674-3515           AB007872.1         2623-3464
            3516-5648           AC005261.2         41975-44107
            5649-7645           AB007872.1         3705-5701
            7646-7646           AC005261.2         46105-46105
            7647-8474           AB007872.1         5703-6530
            8475-11889          AC005261.2         46934-50348
            11890-12163         BF063192.1         10-283              c
FEATURES             Location/Qualifiers
     source          1..12163
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="19"
                     /map="19q13.43"
     gene            1..12163
                     /gene="ZNF264"
                     /note="zinc finger protein 264"
                     /db_xref="GeneID:9422"
                     /db_xref="HGNC:HGNC:13057"
                     /db_xref="MIM:604668"
     exon            1..447
                     /gene="ZNF264"
                     /inference="alignment:Splign:2.1.0"
     CDS             415..2298
                     /gene="ZNF264"
                     /codon_start=1
                     /product="zinc finger protein 264"
                     /protein_id="NP_003408.1"
                     /db_xref="CCDS:CCDS33127.1"
                     /db_xref="GeneID:9422"
                     /db_xref="HGNC:HGNC:13057"
                     /db_xref="MIM:604668"
                     /translation="MAAAVLTDRAQVSVTFDDVAVTFTKEEWGQLDLAQRTLYQEVML
                     ENCGLLVSLGCPVPKAELICHLEHGQEPWTRKEDLSQDTCPGDKGKPKTTEPTTCEPA
                     LSEGISLQGQVTQGNSVDSQLGQAEDQDGLSEMQEGHFRPGIDPQEKSPGKMSPECDG
                     LGTADGVCSRIGQEQVSPGDRVRSHNSCESGKDPMIQEEENNFKCSECGKVFNKKHLL
                     AGHEKIHSGVKPYECTECGKTFIKSTHLLQHHMIHTGERPYECMECGKAFNRKSYLTQ
                     HQRIHSGEKPYKCNECGKAFTHRSNFVLHNRRHTGEKSFVCTECGQVFRHRPGFLRHY
                     VVHSGENPYECLECGKVFKHRSYLMWHQQTHTGEKPYECSECGKVFLESAALIHHYVI
                     HTGEKPFECLECGKAFNHRSYLKRHQRIHTGEKPFVCSECGKAFTHCSTFILHKRAHT
                     GEKPFECKECGKAFSNRKDLIRHFSIHTGEKPYECVECGKAFTRMSGLTRHKRIHSGE
                     KPYECVECGKSFCWSTNLIRHAIIHTGEKPYKCSECGKAFSRSSSLTQHQRMHTGKNP
                     ISVTDVGRPFTSGQTSVTLRELLLGKDFLNVTTEANILPEETSSSASDQPYQRETPQV
                     SSL"
     exon            448..574
                     /gene="ZNF264"
                     /inference="alignment:Splign:2.1.0"
     exon            575..670
                     /gene="ZNF264"
                     /inference="alignment:Splign:2.1.0"
     exon            671..12163
                     /gene="ZNF264"
                     /inference="alignment:Splign:2.1.0"
     regulatory      12142..12147
                     /regulatory_class="polyA_signal_sequence"
                     /gene="ZNF264"
                     /note="hexamer: ATTAAA"
     polyA_site      12163
                     /gene="ZNF264"
                     /note="major polyA site"
ORIGIN      
        1 attttcttct gcacttctgt ctggagaggt ctgtagccac tgagggcccc ggtcggggcc
       61 gctttgcagg tccctagtca ggaccgagca ggggagtagg ataggaatcc ccgccgcacc
      121 tttgtacgag cctgacccct tccgtgggtt tgttcctggg tcgccgtcaa gctgcggtct
      181 ctcctccccc gcccttcagc cccgcggtct ccaggggcgg cgccctgggt ctggaacgcg
      241 gttgccaccg aggaggcggc ggccctgcgt ctggaacgcc gttgccaccg aggaggcggc
      301 ggccccgagc gcgcctggaa gccccgggca accggccagg gtcgggcaca ggtggggtcc
      361 gtcaggccgc ccggggctcc tctgtcccag ctctgcggcc cagggggtga cgtgatggcg
      421 gcagcggtgc tgacggaccg ggcccaggtg tctgtgacct ttgatgatgt ggctgtgact
      481 ttcaccaagg aggagtgggg gcagctggac ctagctcagc ggaccctgta ccaggaggtg
      541 atgctggaaa actgtgggct cctggtgtct ctggggtgtc ctgttcccaa agctgagctg
      601 atctgccacc tagagcatgg gcaggagcca tggaccagga aggaagacct ctcccaagac
      661 acctgtccag gcgacaaagg aaaacctaag accacagaac ctaccacttg tgagccagcc
      721 ttgtcagagg gaatctcact tcagggacaa gtgacacaag gaaactcagt ggactcacag
      781 ttggggcaag ccgaggatca ggatgggcta tcagaaatgc aggaaggaca cttcagacca
      841 ggaatagatc cccaggagaa gtctcctggg aagatgagcc ctgaatgtga tggtttaggg
      901 acagctgatg gtgtgtgttc aaggattgga caggagcaag tctctccagg agatagagtc
      961 cgtagccata actcatgtga gtcaggtaaa gatcccatga ttcaggaaga ggaaaataac
     1021 tttaaatgca gtgaatgtgg aaaagtattt aacaagaaac acctccttgc tggacatgag
     1081 aaaattcact ctggagttaa gccctatgaa tgcacagaat gtgggaaaac ctttattaag
     1141 agcacacatc tcctgcaaca tcacatgatc cacactgggg agaggcccta tgagtgcatg
     1201 gagtgtggaa aggccttcaa ccgcaagtca taccttaccc agcaccagcg gattcacagt
     1261 ggagagaagc cttacaagtg caatgaatgc ggaaaggcct tcacccaccg ctccaatttt
     1321 gtcttgcata acaggagaca cactggagaa aaatcctttg tgtgcacaga atgtggccaa
     1381 gtctttcgac ataggccagg ctttctccgg cactatgttg tccacagtgg tgagaatccc
     1441 tatgagtgct tggagtgtgg caaggtcttc aaacacaggt catatctcat gtggcaccag
     1501 cagactcata ccggggagaa gccctatgag tgcagtgaat gtgggaaggt cttcttggag
     1561 agtgcagccc tgattcacca ctatgtcatc cacactggag agaagccctt tgagtgcctc
     1621 gagtgtggga aggctttcaa ccaccgatcc tacctcaaga ggcaccagcg gattcacact
     1681 ggggagaagc ccttcgtgtg cagtgaatgt ggaaaggcct tcacccactg ctctactttt
     1741 atcttgcata aaagggccca cactggagaa aagcctttcg agtgcaaaga gtgtgggaaa
     1801 gcctttagca atcggaagga cctcattcgc cacttcagca tccacactgg agagaagccc
     1861 tatgagtgcg tggagtgtgg aaaggccttc acccgcatgt cgggcctcac gaggcacaag
     1921 cggattcata gtggagagaa gccctatgaa tgtgttgagt gtgggaaatc gttttgctgg
     1981 agcacaaacc tcattcgaca tgccattatc cacactggag agaagcccta taaatgtagt
     2041 gaatgtggaa aggccttcag tcgcagctcg tccctcactc agcatcaaag gatgcatact
     2101 gggaaaaatc ccatcagtgt aacagatgtg ggaagacctt ttacaagtgg acaaacctca
     2161 gttacccttc gagaacttct tttagggaag gactttttga atgtaaccac tgaggcaaat
     2221 attttgccag aggaaacatc ttcctctgca tctgatcaac cataccaaag agaaacccca
     2281 caagtgtctt cactgtgaga aaaccttctg ttgctgaata ttacttgtca tctgaagagt
     2341 catattagaa attcgttcag tctagagcct tattctccat ctgataattt atcctggaga
     2401 gagacccagt ggttattgtg cacataggag aaccttcagc tgcatctttc tccttagttt
     2461 acagtgcaat tttatctcag gaattatttt taaaaggagg aggggacata gaaaaaatga
     2521 aatgcaagca cacatctttt caggcttctc tgccaagcct atggcgcttt gtcatggatt
     2581 tcttagtgta tttgggggaa gggaaatgtt tcaaggtaaa gaaccttgac cctttatgtg
     2641 cttgtatgta catttattgc tatccagtgt cagaacagtt agtttaggaa aagtatgcaa
     2701 actttaatcg cacatcttct gtattccaca atagtactta ctcttgagaa gcataacttt
     2761 atgacaactt agggggcttg agccatgaaa tactcacgtt taagtcagta aggatacaca
     2821 tgttaacatt caggcttttg tcttgatgcc cgtcttttgg tttacgtcat cattgtagcc
     2881 atatggtaaa tttttatttg ttaaattttt aaaaattact tagctcaaaa tgtcagtggt
     2941 aaatttttaa attgagtaaa gtgattcttc tttgctctta tttaaaatcg acagcatttc
     3001 tagttccttt gacattccat ataattttta ggattagttt gtacttattt acaaaacagt
     3061 cttgttcaga tttttacaga aattgagtta agtctgtgga ttaatctgtt aagaattggt
     3121 atctttacta tgttgggtct tgtagttcat gagtgcagga gtaggcctct taatttataa
     3181 tagttaagca ttccttaaag tatttcatta atgttaaaaa ttttcagcgt atagatccct
     3241 atgcattttt gttagaattt gcatcctagg gtgctttttt gtttgtgtgt gtgtgtaatt
     3301 tgagtgattg taaatggcat tgatgtttga actttgaatt gcacacaatt tttggtagta
     3361 tacagaaata taatattttt ggacattgtt ttgctaccct gcaaccttat tgagttcact
     3421 tattattttt agctatttct ttcgacagaa tccttggaat tttctatata gaaatgtcat
     3481 ctgcaaatac agaccatttt ttatctttca tcttacctgt aatatacctt ttatttcctt
     3541 tttgtttgtc ttattgcatt gcacaagctg ggacttccat tatagcgttg aataggaata
     3601 gtgagaaagg ccatccttac ctggttcctg atagtagggg ggacaatgtt cagttttttg
     3661 tttttttgtt ttttgtttga gacagggtct cgctctgtca cccaggctgg agtgcagtgg
     3721 cacgatcttg tctcaccata gccttaagtt cctgggctca agtgatcccc ccacctcagc
     3781 cctcaccacc ccccagtagc tggtactaca agcatgcacc accagtccca gctaattttt
     3841 gtattttttg gtagagacag ggtttcacca tggtgcccag gctggtcttg aactcctggg
     3901 ctcaagcaac ctgcttgcct gggtctccca aagtgctggg attacaggcg tgagccacag
     3961 tgcacagcat gttcagtttt tcatcatgaa gtataatgta agttttataa aacatatgtc
     4021 ctctataagg gtaaaaaatt tcctctgttc ccagttttct gagactctgt gttgctatga
     4081 ataagtgtgg aattttgttc agtacttttt ctccaccagt tgatgtcatt atgctatttt
     4141 ccttctacat cctattgatg gaatgtattg ctttgatcaa gttttgaata ttgagccagc
     4201 cttgcatcct tagaataaac catacttgtt tgtagagtat aattgttttt atatatcatt
     4261 tgacatcatt ccctttgttt gtattttgtt gaggaaatat tcctctaatt tattggctaa
     4321 taatgtgtag ttcttttttc ttttgtttct tatgttctaa atgtcttatg tgtggttttg
     4381 atgtctaggt gatcttgacc tttcaacatg aattggaagg agttctcttc taatttttgg
     4441 aagactgtgt agaattggtg ttatttgttc ttgtcatgtt tgatgacctc tagtcaacca
     4501 ttgggccaga gatttttctt ctggaggctt ttaaattaca tatttatttt attggatagg
     4561 tagaactatt cgaagtatct atttcttgtg taataaattt tgatagtctg tcctgttgaa
     4621 ggaatatttc atctgtattt gtagcactcc cttattcttt tgatagcagg atctgcactt
     4681 ctttttattt ttaatattta aaatgtgcat actcatttta tgattgagtc ttcttagaca
     4741 tttatcagtt ttattgcgca tcatgctgaa agatgtaatt tttgcttcat ctctcacttc
     4801 agagaactag cactttatat taatgatttg tctctattct tgatttcttt gatttctgct
     4861 ctgatcggta ttatattcca cttgctttgg ttgtatttgg ctctttctaa cttttcaagg
     4921 tggggtttta gattattgat ttgagatttt tttgcttttt taatgtaagc attacattgt
     4981 ataaatttac ctcatatcac tattggtttg atcccacaag ttttaatgtt ttcattacat
     5041 tttaattcta atagttttta ttttttgaga cattctctct tagccatgaa ttatttaata
     5101 gtatgcttaa ttttctggtg tttggcatat ttgttactga tttctaattt gttccatgtt
     5161 tgatctgact gtttaaatgt gttaacattt ttttatgacc caggataggg tctatcttgt
     5221 ttcgtatagc tgcttgaaaa gaatgggtgt tctgctgtta ctgggtggag tttctataaa
     5281 tgtctctatg atcctgctca ttgttattca agtcagctat gtccttgctg attttctgtc
     5341 cagcatttct gtcagttgct gagaggggtg ttgaagtcct gaacataggc cgggtgcagt
     5401 ggctcacgcc tgtaatccta gcactttgag accactaagg caggtggatc acctgaggcc
     5461 aggagttcga gaccagcctg gccaacatgg caaaaccctg tctactaaaa atacaaaaat
     5521 tagccaggca tggtggcgtg tgcctgtaat cccagctgct ggggggctga ggcaggagga
     5581 tcagttgaac gtgggaggca gaggttgcag tgagctgaga tctcaccact gcactccagc
     5641 ctgggcaaca gagcgagact ctgtctcaac aacaacaaca aaaagtcctg aacatgattg
     5701 tggaagtgtg ttgctctttc aagttctatc actttttgtt tgcaaagttc aaagctgtat
     5761 tgtttggtac atatacatgt aggtttgcca agtctttgtg gtgaattgac tcttctgtca
     5821 ttatgtgatg tcattttttt gccttttaat agtcttgtca atactttacc tgatgttctc
     5881 atagtgactc ctgcatattt tgattaatgt ttgcatggtt aatatttctt cattttattt
     5941 taaagcttac ctgtatcatt acttatgaag tcagtttctt tgaacagcat atactcaggc
     6001 catgcttttt ttattcattc tgcatatgtc tctcttaatt ggtatgttga aatgatttac
     6061 attaaaataa ttattgatat tttagggctt aagtgtgccc ttaaatgatt tttgtgttct
     6121 tttttattgt tcctctgtta tttggggttg tttactagtc ttcctatagg ttacttcacc
     6181 tttttttttt ttaataattt gatttgatac atatgtagtg ttttttagta tagatcctcc
     6241 ttgacttatg atggggttat gtcacaataa acccattgca agttgaaaat actatgtcaa
     6301 atatgcattt aatacaccta ccctgctgaa catcatagcc gatcttgcct tcagaatgct
     6361 cagaaaattt acattagcct gcagttgggc aaaatcatct aacacaaggc ctactttata
     6421 ataaagttac tgcaaagaat tttaaataaa aattcaagtg tggtttctac tgaatgcatg
     6481 tcgcattcgc accattgtaa agtcaagtag taagtcgaac catcctaagt cagggactgt
     6541 ctgtatatat ctgcattttt tagtgattgt tctactatta cagtgtaaat atataactta
     6601 tgacagttta ataagttatc agcaatttag cactttactt ccattaggtt cctttagctt
     6661 acctactaat gtaactatct taagtaatag taattcctct tcaaaaattg agcgctatgt
     6721 tgcaagatgt aatttttctt ttcctttttt ttgagaccaa gtctcactct gtcacccacg
     6781 ctggagtgct gtgatgcgat ctcggctctc tgcaacctct gcctcccggg ttcaagcaat
     6841 taactgcctc agcttcccta gtaatggatt acaggcgccc gccaccacgc ctggctaatt
     6901 tttgtatttt tagtagagac ggggtttcac catcttggcc aggttggtct tgaactcttg
     6961 acctcatgat ccacccgcct cggcccccca aagtgctggg gttacaggtg tgagccactg
     7021 cacccggcca caagatgtaa tttttacttt atctctcaca cgtattttac aaaacgtcat
     7081 gagaaacatt gtctcttgac cttttttttt tttttttttt tttaaagaga cagagtctca
     7141 ctctgtcacc caggctggag tgcagtggca cgatcttggc tcactgcaac ctccgcctcc
     7201 tgggttcaag cgattctcct gcctcagcct cctgagtagc tgggattaca ggtgtgcgcc
     7261 gccacaccca gctaattttg tatttttagt agagacgggg tttcaccatg ttgctcaggc
     7321 tggtctcaaa ctcctgacct tgtgatccgc caaccttggc ctgtcgacct ctttacccat
     7381 tccattgttc attcttcttt cttgaaatcc caaaccttct attaacattt cttttcagtt
     7441 atacactgaa ctttactgta gcctttcttc tagagtaaca aatgttcttt gttttccttc
     7501 ctctaaagat gtctttatgt ttccttcatt cccaaagaat atttttgtgg aatataagat
     7561 tcagagttgg cagttgtttt cttttagact tcagagatgt atctctctgt tctgtacatt
     7621 attgtttaat ataagaaacc tactagcatt caaataatca ttccctattt tacaatgcat
     7681 cagttctgtc aagcttcatt caaagtgttt ttcattgtct ctagtgttca gaagtttggc
     7741 tgtgatgtgc gtggcatgga agtttttggg tgtattctat ttggcgctcc ctggtgcttg
     7801 cccagctttt tgatctgtag gattatgcct tttgcaaaat ttggggaact ttcaactatt
     7861 atttcttcaa atattttttc accccccagt cttgtctttt ttagggactt caataacatg
     7921 agtggcagat cttgttttac actcccatgg gtccttcagg ctctcatctt ttttcttttt
     7981 ccagtctatt ttctgtcttg ttaatattga ttaattttta ttgaccttcc atggtcctca
     8041 ctgattgttt tctttgtcat acctaatctg ttgagtttgt gcagtgagtt ttcattttgg
     8101 ttttgtattt tccagttgtt taatttccat tgggtgggtt cttttgtaca ccttctgttt
     8161 ctttgcttat tttttaacgc caaagaaaga ctctcagaga atagacaact atattccaaa
     8221 gtcatggttc tctggtggtt tgtcttgaca tttgaataga aatgttaaac tatctggggg
     8281 aatagaaagc ccacagtctt ctgagttgtg ctacaccaat atttctatga acagatctta
     8341 caactgagag tgatctgcag atttttcaga gtcatgttct ccatggaatg tttgtaaaat
     8401 tccctagctc tctgcactga gctgagatcg tgccactgca ctccagcctg ggcaacagag
     8461 cgagactcca tctcaaaaaa aaaaaaaatt ctctagctct ctatgccttg ttgtatcctc
     8521 aggaaggagt cacctctctt ccaggatcac tcttgccttt tgttattgga cacattttcc
     8581 tacctcctgc ccagtctttt ttaggctctc tgtcatactt cctcgcctag tctttaactt
     8641 gtctctgata accagatttt tcccccataa tctgtatctg tattcaagtc tctatcctca
     8701 tccccaaatg gatttcaccc cgcttgtcca tcagtctctg cccatttctt ctgtctccca
     8761 cagacatggt ctgtgtagtt gttctgcaca ctacccgtcc tcgccccttc tcatttccct
     8821 cactccacgg acagctacag gagggcttcc atcatttgtc ctcttacttc cttgttagaa
     8881 ctttgtgctg ctgaccacca ctctgaacca aaacttcttt cttggttctt gaaagttgct
     8941 gtctttctcc tccagagggt ctgtgtcttc cttccaactc ttaaacattt ttgtttccca
     9001 gaatccatca ttggccattg ctttttcact tgccatgagc tctgtgaatg agatggttcc
     9061 tgctgaagac atttactttc aatgatctac agaatttccc aaatctatgt ctccagactg
     9121 gatgtttctc acgtctgtgg cccactgggc atcttctgca ctttctctgc atttgtaaac
     9181 actgagcctg tatgcgtgtc tatgtggcca tggccctggc cgtggggatg cacccataat
     9241 tataatgaga gcaggtgaat gtcatgtggc tatgtatgag acattgttgt gaatgtttta
     9301 catgcatcag ctctttcaac atttacagca tctgtgtgtg gtaggtaatg ttgtttcctt
     9361 cattttgcag agcagaatat agataggctc aggttaagaa tttgcccaag gttacacagt
     9421 tatgaagttt ggatttagga atgggaggcc acgtagactg gcttcagaat tcatgtcttt
     9481 aaccacttta ttgcttctca tgttgggggg tttgttttct ggtcactatt tttactaaag
     9541 ttgattcaac aatgctataa tctgttactc tcattcgaca atacatcttg actgtttctt
     9601 caacttgagg aaggtaaacc aaagccactc tttaatgggt gcaaatatct gttgtaacta
     9661 tgtagaagat acagtgtctg ggtttgagga caggggagtg ggaaaactga gtagggaagc
     9721 ggtaagacat gcatctggct ttaggagtgt ttgaagtgcc taaagatcag ggtgaatttc
     9781 ccaaatttga atcttgttgc ccaagccaca ttgcaaccac ctctttttct cttacctcgt
     9841 ccccacatcc aggcactgcc ccattctgtt cattccacct ttttttttag tagaccctcc
     9901 atatatgtgt gtgttttggt gaatggccac acacagcaaa gttattttta ttgcaatttt
     9961 gttgttgttg tttgagacac agagtctcat actctgccac ccagactgaa gtgcagtggt
    10021 gcgatctcag ttcactgcaa cctccatccc cccatgttca agcaattctc ctgcctcagc
    10081 ctcccaagta gctgggatta caggcatggg ccaccatgcc cggctaattt ttgtattttt
    10141 tgtagacacg gggtttcacc atgttggcca ggctggtctc acactcctga cctcaggtga
    10201 tccacccgcc tcggcctccc gaagtgctgg cattacaggc atgagccacc acacccagcc
    10261 tttattgcaa tttttggttc cctcacagaa tgtttaccat gaagctgtgc gtataggtgg
    10321 taccatgtat gacatacctt gacctcaaag ataatctacc tgggcttttt ttgtttgttt
    10381 gttttgagat ggagtctcac tctgtcaccc atgctggtgt gcagtggcgt gatcttggct
    10441 cacagcagcc tctgcctccc gggttcaagc gattctcctg cctcagcctc ctgagtagct
    10501 gggactacag gtgcctgcga ccacacccag ctaatttttg tatttttagt agtagtggga
    10561 tttcaccatg ttggccagga tggcctccac ctcctgactt catgatccac ccgcctcggc
    10621 ctcccaaagt gctgggatta caggcgtgag ccaccgcacc tggcctacct gggctttttt
    10681 ggacagatgt acatgatttt agaaattgtt atgaatgact gtcttgggat cctcaagaac
    10741 acccccaggt ttgacgattt gctgagaaga ctcaggtctc agcattctgt catactcaac
    10801 agctatgatt tactgcagca aaaaaataca aagcaaatag taaagggaaa aagccaaaat
    10861 tcagagaaaa ccaggcacaa tcttctgagt cttgtttcag tgaagtcaca ggatgtgcct
    10921 tatttaagtt ccatctggta cttatgacaa cacatgctat atgtccactg ggaagcttat
    10981 tagagactca gtgccagggt ttttattggg catgttttct agcacatccc acaattctgg
    11041 acttccagaa ggttagcagg ggttcagctt ttcagctgaa aacgttatcc ccctttcagc
    11101 tggggggaaa aaaaggcacc gaaaaacagg gcagtgagct actcctgttt tgggtgggtg
    11161 gagcagtagt aagcctccca aaatctaagg tcccacactc cagcaagggt gaaccttgca
    11221 aactcaaaag gatagcagtc tccaacctgc tgttttatac agtgacttaa gtggtactaa
    11281 aatgctatat aagtcaaatt tacgtaacat taagcaaata attttttttc agcaaaaaaa
    11341 taatggtcat gactttgtgg tgaaggctta tgtaatgatt gtaataaatt caggtggctc
    11401 acgcctgtga taccagcact tttgggaggc tgaggcgggt ggatcacttg aggtcaggag
    11461 tttgagacca gcctagccaa catggtgaaa tcccatctct acaaaaatga aaaattagcc
    11521 gggcgtagtg gtacatgcat ttagtcctag ctacttggga ggctgaggca ggaaaatcgc
    11581 ttgaacctgg gaggcagagg ttgcagtgag ccgagatcat gccactgcac tccagcctgg
    11641 gtgacagagt gagactgtgt ctcaaaaaaa aaaaaaaaaa aaaaatgcct cagttttgtt
    11701 aagaggaaaa agcaaatcct aagttacagt ggaacttatg aacaccctag cctagagatt
    11761 taatttagtg atgaaaaggt acagagagag tctttcaaga aaggacctag tctgctcgcg
    11821 ttctctctct ctctctctct atatatatat atgtatatgt gtgtgtacat atggaccact
    11881 tcaagctaca cacacacaca cacatataca cgtgtatgaa tatatatata tggctataag
    11941 tggtgcgact tgcaggtact ccctttgttc acctttgtaa agatgttatt gccagttcag
    12001 tgtgtatttc tatagtatat atgtaaacaa tttgtcatcc ttttgttgct gcttttgaaa
    12061 ctagttcatg gcttcagtgg gggagagatt taaataatat gggtttataa tttctgcatt
    12121 attaaatgca gataacttgt gattaaagag tatgttattg gaa
//
