LOCUS       NM_001166037            5285 bp    mRNA    linear   PRI 02-APR-2024
DEFINITION  Homo sapiens zinc finger protein 260 (ZNF260), transcript variant
            3, mRNA.
ACCESSION   NM_001166037
VERSION     NM_001166037.2
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 5285)
  AUTHORS   Luck,K., Kim,D.K., Lambourne,L., Spirohn,K., Begg,B.E., Bian,W.,
            Brignall,R., Cafarelli,T., Campos-Laborie,F.J., Charloteaux,B.,
            Choi,D., Cote,A.G., Daley,M., Deimling,S., Desbuleux,A., Dricot,A.,
            Gebbia,M., Hardy,M.F., Kishore,N., Knapp,J.J., Kovacs,I.A.,
            Lemmens,I., Mee,M.W., Mellor,J.C., Pollis,C., Pons,C.,
            Richardson,A.D., Schlabach,S., Teeking,B., Yadav,A., Babor,M.,
            Balcha,D., Basha,O., Bowman-Colin,C., Chin,S.F., Choi,S.G.,
            Colabella,C., Coppin,G., D'Amata,C., De Ridder,D., De Rouck,S.,
            Duran-Frigola,M., Ennajdaoui,H., Goebels,F., Goehring,L., Gopal,A.,
            Haddad,G., Hatchi,E., Helmy,M., Jacob,Y., Kassa,Y., Landini,S.,
            Li,R., van Lieshout,N., MacWilliams,A., Markey,D., Paulson,J.N.,
            Rangarajan,S., Rasla,J., Rayhan,A., Rolland,T., San-Miguel,A.,
            Shen,Y., Sheykhkarimli,D., Sheynkman,G.M., Simonovsky,E., Tasan,M.,
            Tejeda,A., Tropepe,V., Twizere,J.C., Wang,Y., Weatheritt,R.J.,
            Weile,J., Xia,Y., Yang,X., Yeger-Lotem,E., Zhong,Q., Aloy,P.,
            Bader,G.D., De Las Rivas,J., Gaudet,S., Hao,T., Rak,J.,
            Tavernier,J., Hill,D.E., Vidal,M., Roth,F.P. and Calderwood,M.A.
  TITLE     A reference map of the human binary protein interactome
  JOURNAL   Nature 580 (7803), 402-408 (2020)
   PUBMED   32296183
REFERENCE   2  (bases 1 to 5285)
  AUTHORS   Debrus,S., Rahbani,L., Marttila,M., Delorme,B., Paradis,P. and
            Nemer,M.
  TITLE     The zinc finger-only protein Zfp260 is a novel cardiac regulator
            and a nuclear effector of alpha1-adrenergic signaling
  JOURNAL   Mol Cell Biol 25 (19), 8669-8682 (2005)
   PUBMED   16166646
  REMARK    GeneRIF: Zfp260 is a novel transcriptional regulator in normal and
            pathological heart development and a nuclear effector of
            alpha1-adrenergic signaling
REFERENCE   3  (bases 1 to 5285)
  AUTHORS   Robertson,N.G., Khetarpal,U., Gutierrez-Espeleta,G.A., Bieber,F.R.
            and Morton,C.C.
  TITLE     Isolation of novel and known genes from a human fetal cochlear cDNA
            library using subtractive hybridization and differential screening
  JOURNAL   Genomics 23 (1), 42-50 (1994)
   PUBMED   7829101
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AK291442.1 and AC092295.2.
            
            On Nov 23, 2018 this sequence version replaced NM_001166037.1.
            
            Transcript Variant: This variant (3) differs in the 5' UTR compared
            to variant 1. All variants (1-4) encode the same protein.
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR1803616.188282.1,
                                           SRR1660807.210836.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN03267768, SAMN03267769
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000523638.6/ ENSP00000429803.1
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-803               AK291442.1         2-804
            804-5285            AC092295.2         55694-60175         c
FEATURES             Location/Qualifiers
     source          1..5285
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="19"
                     /map="19q13.12"
     gene            1..5285
                     /gene="ZNF260"
                     /gene_synonym="OZRF1; PEX1; ZFP260"
                     /note="zinc finger protein 260"
                     /db_xref="GeneID:339324"
                     /db_xref="HGNC:HGNC:13499"
                     /db_xref="MIM:613749"
     exon            1..53
                     /gene="ZNF260"
                     /gene_synonym="OZRF1; PEX1; ZFP260"
                     /inference="alignment:Splign:2.1.0"
     exon            54..272
                     /gene="ZNF260"
                     /gene_synonym="OZRF1; PEX1; ZFP260"
                     /inference="alignment:Splign:2.1.0"
     exon            273..5285
                     /gene="ZNF260"
                     /gene_synonym="OZRF1; PEX1; ZFP260"
                     /inference="alignment:Splign:2.1.0"
     CDS             734..1972
                     /gene="ZNF260"
                     /gene_synonym="OZRF1; PEX1; ZFP260"
                     /note="zfp-260"
                     /codon_start=1
                     /product="zinc finger protein 260"
                     /protein_id="NP_001159509.1"
                     /db_xref="CCDS:CCDS33003.1"
                     /db_xref="GeneID:339324"
                     /db_xref="HGNC:HGNC:13499"
                     /db_xref="MIM:613749"
                     /translation="MIGMLESLQHESDLLQHDQIHTGEKPYECNECRKTFSLKQNLVE
                     HKKMHTGEKSHECTECGKVCSRVSSLTLHLRSHTGKKAYKCNKCGKAFSQKENFLSHQ
                     KHHTGEKPYECEKVSIQMPTIIRHQKNHTGTKPYACKECGKAFNGKAYLTEHEKIHTG
                     EKPFECNQCGRAFSQKQYLIKHQNIHTGKKPFKCSECGKAFSQKENLIIHQRIHTGEK
                     PYECKGCGKAFIQKSSLIRHQRSHTGEKPYTCKECGKAFSGKSNLTEHEKIHIGEKPY
                     KCNECGTIFRQKQYLIKHHNIHTGEKPYECNKCGKAFSRITSLIVHVRIHTGDKPYEC
                     KVCGKAFCQSSSLTVHMRSHTGEKPYGCNECGKAFSQFSTLALHMRIHTGEKPYQCSE
                     CGKAFSQKSHHIRHQRIHTH"
     regulatory      5259..5264
                     /regulatory_class="polyA_signal_sequence"
                     /gene="ZNF260"
                     /gene_synonym="OZRF1; PEX1; ZFP260"
                     /note="hexamer: AATAAA"
     polyA_site      5285
                     /gene="ZNF260"
                     /gene_synonym="OZRF1; PEX1; ZFP260"
                     /note="major polyA site"
ORIGIN      
        1 aggagtgcgc aggcgcggaa tctccgactt gccatggtcg tctttgtctg ccggcctgct
       61 tccttgtata tccacaggag ctgcaaaacc tcttagagtt ctaagggcgc tccctgaatt
      121 ttgggatgct gctttgttcc ccaaccataa catccaagtc cagtgtcatt tttctgctca
      181 caagtttaaa gtcagcactt aaaagaacag caacagatga ttgagaaaga aatgtaaaga
      241 aggttctctt tgtgtgagta agcaagaacc tgaagaagcc tgggaagttt ataaacagat
      301 aaagacgcaa catgaaagac ttgtaagtta agtctcatct ttctctgtga aaagacagac
      361 tgagggaaaa tttaggaaac aaagtatttc ctctgaacag tcattgattc ttcaagacta
      421 cccttctgtg tatggaactc agtttaaaag aatttgaaac ctaatttata tacaatctat
      481 acctaaatat gggagaagct atataagaac cattaagaat ataaagagaa tgttacattt
      541 tatccctttt tgtaatcatc tcatctcagg gtaatcaatg tgagaaaagt cttccatcat
      601 aaatttaact tcattagata cctgagaatt aatattgaaa atacaccata tgaatttagt
      661 gaatgtggga aagctttcat ccttattaca tcttatttga tactagggaa atctcctgat
      721 taaattcaca tgcatgatag gcatgttgga aagtcttcag catgaatcag atctccttca
      781 gcatgatcaa attcatactg gagagaaacc ttatgaatgt aatgaatgta gaaaaacttt
      841 tagcctgaag caaaaccttg tagagcataa gaaaatgcat actggagaga aatctcatga
      901 atgcactgaa tgtggtaaag tgtgctctcg agtctcatct cttactctac accttagaag
      961 tcacacagga aagaaggcat ataaatgtaa taaatgtgga aaagccttca gccagaagga
     1021 aaacttcctt tctcatcaga aacatcacac tggagagaaa ccttatgaat gtgaaaaagt
     1081 ttctattcag atgccaacca tcatcagaca ccagaaaaat catacaggaa ccaaacccta
     1141 tgcatgtaag gaatgtggca aagcctttaa cggcaaagca tatctcactg agcatgagaa
     1201 aattcatact ggagaaaaac catttgaatg taatcagtgt ggaagagcct tcagccagaa
     1261 gcaatacctc attaaacatc agaacatcca tactggaaag aagcccttta aatgtagtga
     1321 gtgtggaaaa gcttttagcc agaaggaaaa cctcattata catcagagaa tccatactgg
     1381 agagaaacct tatgaatgta aagggtgtgg gaaagctttc attcagaagt caagcctcat
     1441 tagacaccag agaagtcaca caggagagaa accttatacg tgtaaggaat gtgggaaagc
     1501 cttcagtggc aagtcaaatc tcacagagca tgagaaaatt catattggag agaaacccta
     1561 caaatgtaat gaatgtggaa caatcttcag gcagaagcaa tacctcatta aacatcacaa
     1621 tattcataca ggagagaaac cctatgaatg taataaatgt ggaaaagcct tctctcgaat
     1681 cacatcactt attgtacatg tgagaattca tacaggtgat aagccttatg agtgtaaggt
     1741 ctgtgggaaa gccttctgtc aaagctcatc tcttactgtg catatgagaa gccatacagg
     1801 tgagaaaccc tatggttgta atgaatgtgg gaaagccttt tctcagttct caacccttgc
     1861 tctgcacatg agaatccata ctggtgaaaa accttatcag tgtagtgaat gtgggaaagc
     1921 tttcagccaa aagtcacatc acattagaca ccagagaatt catactcatt aaagttctct
     1981 atgaatgcct tggatttagc aaaacgttca gcagatttta cacttaatag tgtattggaa
     2041 aattcatttt acattaaagt gacatgaatg tgggaagtcc ttcagcagca attcaaaact
     2101 taaatactat gatgtttaat aagtattata gtgtaaagaa aacccgtacc cccaaaactc
     2161 ccacaacaag cattatcaat gctgtacttc taggagtata ctcattaaag ttaggatcta
     2221 gtcatggaca ctacttaatg tgttcctgga aggcctacag atgcattaag aaatagatat
     2281 gagatgtatg aggatttgaa attaagagac aaaattatca tttttgtgat gttttgctac
     2341 atatatgaat tgtaaaacta gaatcatcaa aattatttgt tgttgaagca gtcataaaac
     2401 tgagactgag acagaatatt gaattcagaa atgtgtgcat gaatatatgg ggaattggta
     2461 attgatagag gcggtatccc agattggtgg ggaaatcatg gattacttaa aaattaattg
     2521 actcttcata tggaaaaata atatctccca tcataatata aaatattttt cttatgaatt
     2581 cttaaagtac taaagactaa aatgcaaaaa gcaatactta ataatataac agttttataa
     2641 gaagatgttt ttaaaacctt agggcaggaa agaacttcta aaacattcca gaatacccgg
     2701 tagttccact cttgagtatg gtagtcccct attttctgca agagatggac tctaagaccc
     2761 ccagtggata cctaaaaccc agataggacc aaactctatg tctatgtttt tttcttatat
     2821 atacatacct atgataaaat ttagtttaca gattagacac agcaagagat ttaaaacaat
     2881 aataaacata atatggaaca attataacaa tatactgtaa tcataaaagt tatgtgaata
     2941 tgatctttct ctcagaatac cttattgtac tgttctcaac tatttatgaa ctgtggtgac
     3001 tacaggtaac tgaaaccatg gaaagcaaag ctgtggataa gggggaacta ctatatatat
     3061 gcatctaccc aagaaacatg aacacaggga gtcatgtact ggtctatagc tgtatagttc
     3121 attgcaccat gagttatagt agccagaagt tgggaaacaa atgctgtctc ttgtgaaata
     3181 gatgaataaa atgtgatagt aacatagtag agtactctct agcagttaag tgacaaatta
     3241 agtctatata ttaacagaaa tatttttaaa aaattagagt gaagaaaaat gatgaacata
     3301 ttgtaatgat gcttctgtga atttgaataa aatcaacact aaccagccct agtactaaga
     3361 attggttatg gataaattat gtaaaactaa agaatggatt gaaaggatat gtatatactc
     3421 agttcccaaa agtggagtgg ttacctctag gaagaaagga ggtggaaggg aaatgttacc
     3481 aagcatggta gttaaaggat acttcaattt tgtatctatt tcttattaaa aagaaacatt
     3541 ctaagtaaac ataacgaaat attaattctg ggtggtggta atatttgtgt tcattctatc
     3601 attcgtgcta tttatttcct taaacttctg aaagttaaaa agtccagata ggagtgagga
     3661 agctgtacat gaaacataat ggacttacat tcctagtcag atactaatat tctgtagaag
     3721 atatttctaa aatcttatct ttaaaatatg aaataatttt taattggggt ggcaacttaa
     3781 attcaattaa aataactcat gtgtcacaag agtaaatttt acataatctg tacgtagttc
     3841 taatctgtat atagtcttgg aggttatgat ttgccacaga ttggttggat cacatacatt
     3901 taaggatcat attattaaat aatatatgca cagacatgga gagaattagt ttttactaaa
     3961 acatttatca gaaattttaa tactctgcat aaccagtatt agcattagaa attagccact
     4021 tttaaaatga gaaaactgtg tcactcttca atttttttat aagccattga ggaaaacatt
     4081 aactcctgga tttcagcttc acttttaacc tgcagactaa atttctttct caattatgtc
     4141 agacacaccc aagtcaatcc caaccccctt gttaccttgg gaagaccgtg ctgaaaaagg
     4201 agatcttcca cctaaacagt gttctcttat ttgaagcaaa tctttttgag aatttgttta
     4261 cttgatttct ttccacaata aactgacaga gaacgctact aatgattttt tttttttttt
     4321 gagacggagt tttgttcttg ttgcccaggc tgcagtgcaa tggcacaatc ttggctcact
     4381 gcaacctctg cctcacaggt tcaagtggtt ctcctgcctc agcctcttga gtagctggga
     4441 ttacaggcat gcgccaccat gcccggctaa ttttgtattt ttagtagaga cggagttgca
     4501 ccatgttggc caggctggtc ttgaattcct gacctcaggt gatccacctg cttcggcctc
     4561 ccaaagtgct aggattacag gtgtgagcca ccacgcctgg ctaattttgt atttttagta
     4621 gagatggggt ttctccaaag gctggtcttg aactcccgac ctcaggtgat ccgcccacct
     4681 tggcctcccg aagtgctggg attacaggcg tgagccaccg tgcccggcct gatgtttttg
     4741 aatgattatg aaaatgggta tacagcatta aaaccttaga ctgattttaa atatattaat
     4801 ttcttttaaa ctcaatataa tgttaatatt actgtagcac ttactagcat ttctgaaggt
     4861 tggtcttgag ataagattga aaatgacagt tgttgatttt ctgaggtaat atacccaaat
     4921 aaaatatatg tatgtgtaca tgaatctaaa ctgtcttctt ctgttcctca ttttgcttta
     4981 cttaaataat ctttcatatt ttttaagtgt tttgcccatg tgcttgggta gccttgaagt
     5041 caccagaata actaggactc aaattcagac caaaccagga ctagcttttt gtgccatgag
     5101 ttagccatgg tcctggaccc agcaaaaaga atgattatga tggtcagagt aagatgagca
     5161 attgcaacat aatattctct aatattgtat actgtaaatt tattcagctg ccctcgttta
     5221 ctcacagttt gcttatttgc caccataaga aatggtacaa taaaaattca tgtaatcacc
     5281 cctta
//
