LOCUS       NM_005773               2207 bp    mRNA    linear   PRI 02-APR-2024
DEFINITION  Homo sapiens zinc finger protein 256 (ZNF256), transcript variant
            1, mRNA.
ACCESSION   NM_005773
VERSION     NM_005773.3
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 2207)
  AUTHORS   Luck,K., Kim,D.K., Lambourne,L., Spirohn,K., Begg,B.E., Bian,W.,
            Brignall,R., Cafarelli,T., Campos-Laborie,F.J., Charloteaux,B.,
            Choi,D., Cote,A.G., Daley,M., Deimling,S., Desbuleux,A., Dricot,A.,
            Gebbia,M., Hardy,M.F., Kishore,N., Knapp,J.J., Kovacs,I.A.,
            Lemmens,I., Mee,M.W., Mellor,J.C., Pollis,C., Pons,C.,
            Richardson,A.D., Schlabach,S., Teeking,B., Yadav,A., Babor,M.,
            Balcha,D., Basha,O., Bowman-Colin,C., Chin,S.F., Choi,S.G.,
            Colabella,C., Coppin,G., D'Amata,C., De Ridder,D., De Rouck,S.,
            Duran-Frigola,M., Ennajdaoui,H., Goebels,F., Goehring,L., Gopal,A.,
            Haddad,G., Hatchi,E., Helmy,M., Jacob,Y., Kassa,Y., Landini,S.,
            Li,R., van Lieshout,N., MacWilliams,A., Markey,D., Paulson,J.N.,
            Rangarajan,S., Rasla,J., Rayhan,A., Rolland,T., San-Miguel,A.,
            Shen,Y., Sheykhkarimli,D., Sheynkman,G.M., Simonovsky,E., Tasan,M.,
            Tejeda,A., Tropepe,V., Twizere,J.C., Wang,Y., Weatheritt,R.J.,
            Weile,J., Xia,Y., Yang,X., Yeger-Lotem,E., Zhong,Q., Aloy,P.,
            Bader,G.D., De Las Rivas,J., Gaudet,S., Hao,T., Rak,J.,
            Tavernier,J., Hill,D.E., Vidal,M., Roth,F.P. and Calderwood,M.A.
  TITLE     A reference map of the human binary protein interactome
  JOURNAL   Nature 580 (7803), 402-408 (2020)
   PUBMED   32296183
REFERENCE   2  (bases 1 to 2207)
  AUTHORS   Suzuki,C., Murakumo,Y., Kawase,Y., Sato,T., Morinaga,T., Fukuda,N.,
            Enomoto,A., Ichihara,M. and Takahashi,M.
  TITLE     A novel GDNF-inducible gene, BMZF3, encodes a transcriptional
            repressor associated with KAP-1
  JOURNAL   Biochem Biophys Res Commun 366 (1), 226-232 (2008)
   PUBMED   18060868
  REMARK    GeneRIF: These findings suggest that BMZF3 is a transcriptional
            repressor induced by GDNF that plays a role in cell proliferation.
REFERENCE   3  (bases 1 to 2207)
  AUTHORS   Imabayashi,H., Mori,T., Gojo,S., Kiyono,T., Sugiyama,T., Irie,R.,
            Isogai,T., Hata,J., Toyama,Y. and Umezawa,A.
  TITLE     Redifferentiation of dedifferentiated chondrocytes and
            chondrogenesis of human bone marrow stromal cells via chondrosphere
            formation with expression profiling by large-scale cDNA analysis
  JOURNAL   Exp Cell Res 288 (1), 35-50 (2003)
   PUBMED   12878157
REFERENCE   4  (bases 1 to 2207)
  AUTHORS   Han,Z.G., Zhang,Q.H., Ye,M., Kan,L.X., Gu,B.W., He,K.L., Shi,S.L.,
            Zhou,J., Fu,G., Mao,M., Chen,S.J., Yu,L. and Chen,Z.
  TITLE     Molecular cloning of six novel Kruppel-like zinc finger genes from
            hematopoietic cells and identification of a novel transregulatory
            domain KRNB
  JOURNAL   J Biol Chem 274 (50), 35741-35748 (1999)
   PUBMED   10585455
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC010326.7.
            
            On Nov 23, 2018 this sequence version replaced NM_005773.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC001438.1, SRR3476690.257381.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA1965299, SAMEA1966682
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000282308.4/ ENSP00000282308.2
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-265               AC010326.7         102015-102279       c
            266-392             AC010326.7         98507-98633         c
            393-2207            AC010326.7         95406-97220         c
FEATURES             Location/Qualifiers
     source          1..2207
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="19"
                     /map="19q13.43"
     gene            1..2207
                     /gene="ZNF256"
                     /gene_synonym="BMZF-3; BMZF3"
                     /note="zinc finger protein 256"
                     /db_xref="GeneID:10172"
                     /db_xref="HGNC:HGNC:13049"
                     /db_xref="MIM:606956"
     exon            1..265
                     /gene="ZNF256"
                     /gene_synonym="BMZF-3; BMZF3"
                     /inference="alignment:Splign:2.1.0"
     CDS             233..2116
                     /gene="ZNF256"
                     /gene_synonym="BMZF-3; BMZF3"
                     /note="isoform 1 is encoded by transcript variant 1; bone
                     marrow zinc finger 3"
                     /codon_start=1
                     /product="zinc finger protein 256 isoform 1"
                     /protein_id="NP_005764.2"
                     /db_xref="CCDS:CCDS12966.1"
                     /db_xref="GeneID:10172"
                     /db_xref="HGNC:HGNC:13049"
                     /db_xref="MIM:606956"
                     /translation="MAAAELTAPAQGIVTFEDVAVYFSWKEWGLLDEAQKCLYHDVML
                     ENLTLTTSLGGSGAGDEEAPYQQSTSPQRVSQVRIPKALPSPQKTNPCEICGPVLRQI
                     LHLVEHQGTHHGQKLYTDGACRKQLQFTAYLHQHQKQHVGQKHFRSNGGRDMFLSSCT
                     FEVSGKPFTCKEVGKDFLVRSRFLQQQAAHTRKKSNRTKSAVAFHSVKNHYNWGECVK
                     AFSYKHVRVQHQGDLIRERSYMCSECGKSFSTSCSLSDHLRVHTSEKPYTCGECGKSY
                     RQSSSLITHRRIHTGVRPHQCDECGKLFNRKYDLLIHQRVHTGERPYKCSECGKSFSH
                     SSSLITHQRIHTGMRPYECSECGKSFIHSSSLITHQRVHTGTRPYMCSECGKSFSQSC
                     HLIKHRRLHIGEGPYECSECGKLFTYRSRFFQHQRVHTGVRSHECHECGKLFSRKFDL
                     IVHERVHTGERPYECSECGKSFTCKSYLISHWKVHTGARPYECGECGKSFTHSSTLLQ
                     HQRVHTGERPYECNECGKFFSQSSSLIRHRRSHTGERPYECSECWKSFSNHSSLVKHR
                     RVHTGERPYECSECGKSFSQSSNLTNHQRIHSGERPYECSDCGKFFTFNSNLLKHQNV
                     HKG"
     exon            266..392
                     /gene="ZNF256"
                     /gene_synonym="BMZF-3; BMZF3"
                     /inference="alignment:Splign:2.1.0"
     exon            393..2207
                     /gene="ZNF256"
                     /gene_synonym="BMZF-3; BMZF3"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2186..2191
                     /regulatory_class="polyA_signal_sequence"
                     /gene="ZNF256"
                     /gene_synonym="BMZF-3; BMZF3"
                     /note="hexamer: AATAAA"
     polyA_site      2207
                     /gene="ZNF256"
                     /gene_synonym="BMZF-3; BMZF3"
                     /note="major polyA site"
ORIGIN      
        1 gggacttccg ttgtcctcct tgtggcggtc gttttggcat ttgtctggac tgattacttg
       61 gtagaaagcc ccggagcgct gggtcagcat catccgtgac tgactgagaa ggcgcgagag
      121 gagtcttccc cgctgcacag aggcgtggct gaggctcggc ggcgcccagg gtacccaggc
      181 ccggcccgga ataaggacat cctctctggc cccgctccgc tcacagagtc agatggcggc
      241 ggccgagctg acggccccgg cccagggcat tgtgaccttt gaggacgtgg ctgtttactt
      301 ctcctggaag gagtggggtc ttcttgatga ggctcagaaa tgcctgtacc acgatgtgat
      361 gctggagaac ttgacactta caacctccct gggtggttct ggagcagggg atgaggaggc
      421 accttatcag cagagcactt ctccacagcg ggtgtcacag gttaggattc ctaaggccct
      481 tccttctccc cagaagacca acccctgtga gatatgtggc ccagtcttga gacagatttt
      541 gcacttggtt gaacaccaag gaacacacca tggtcagaaa ctgtatacag acggggcatg
      601 taggaaacaa ttacaattta ctgcatacct tcatcagcac cagaagcagc atgttggaca
      661 gaaacacttc agaagcaatg ggggcagaga catgtttttg agcagctgca catttgaagt
      721 atctgggaag cccttcactt gcaaggaggt tgggaaggat ttcctggtga gatcaagatt
      781 tcttcagcaa caggctgctc acaccagaaa gaagtcaaac agaaccaaga gtgcagtggc
      841 ctttcacagt gtaaaaaatc attacaactg gggagaatgt gtgaaagctt tcagctacaa
      901 acatgtacgt gttcagcacc agggagacct cattagggaa agatcttaca tgtgcagtga
      961 atgtgggaaa tcttttagca caagctgtag cctcagtgat catttgagag ttcacacttc
     1021 agaaaagcct tatacatgtg gagaatgtgg gaaatcctat aggcaaagct ctagccttat
     1081 tacgcaccga agaattcaca ctggagtaag acctcatcaa tgtgatgaat gtggaaaatt
     1141 atttaacagg aagtatgacc ttcttataca tcagagagtt catactggag aaaggcctta
     1201 caagtgcagt gaatgtggga aatcctttag ccatagctct agcctcatta cacaccagag
     1261 aattcatact ggaatgaggc cttatgagtg cagtgaatgt gggaaatctt ttatccatag
     1321 ttctagcctt attacacacc agagagttca cactggtaca aggccttata tgtgcagtga
     1381 atgtgggaaa tcctttagcc agagctgtca cctcattaaa caccggagac ttcacattgg
     1441 agaagggcct tatgagtgta gtgaatgtgg gaaattgttt acttatagat ctcgtttctt
     1501 ccaacaccag agagttcata ctggagtaag atctcatgaa tgtcatgaat gtggaaaatt
     1561 atttagcagg aaatttgacc tcattgtaca tgagagagtt cacacaggag aaaggccata
     1621 tgagtgcagt gaatgtggaa aatcctttac ctgtaaatcc tacctcatct cacactggaa
     1681 agttcatact ggagcaaggc cttatgaatg tggggagtgt gggaaatcat ttactcatag
     1741 ctctacgctc cttcaacacc agagagttca cactggagaa aggccttatg agtgcaatga
     1801 atgtgggaag ttttttagcc agagctccag cctcattaga cataggagaa gtcacaccgg
     1861 agaaaggcct tatgagtgca gtgagtgttg gaaatccttt agtaaccact ctagcctcgt
     1921 taaacaccga agagttcata ccggagaaag gccttatgaa tgcagtgaat gtggaaaatc
     1981 ctttagccag agctctaacc tcactaatca ccagcgaatt cacagtgggg aaaggcctta
     2041 tgagtgtagt gactgtggaa aattttttac cttcaactcc aacctcctaa aacatcagaa
     2101 cgttcacaag ggataaaggt taggtaacac acatagggct gttacggact gagaagtgtc
     2161 cctgcaaaat tcacagacat aaataaataa atacgtattt tcaataa
//
