LOCUS       NM_006630               4607 bp    mRNA    linear   PRI 02-APR-2024
DEFINITION  Homo sapiens zinc finger protein 234 (ZNF234), transcript variant
            1, mRNA.
ACCESSION   NM_006630
VERSION     NM_006630.3
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 4607)
  AUTHORS   Lovering,R.C., Gaudet,P., Acencio,M.L., Ignatchenko,A., Jolma,A.,
            Fornes,O., Kuiper,M., Kulakovskiy,I.V., Laegreid,A., Martin,M.J.
            and Logie,C.
  TITLE     A GO catalogue of human DNA-binding transcription factors
  JOURNAL   Biochim Biophys Acta Gene Regul Mech 1864 (11-12), 194765 (2021)
   PUBMED   34673265
REFERENCE   2  (bases 1 to 4607)
  AUTHORS   Shannon,M., Hamilton,A.T., Gordon,L., Branscomb,E. and Stubbs,L.
  TITLE     Differential expansion of zinc-finger transcription factor loci in
            homologous human and mouse gene clusters
  JOURNAL   Genome Res 13 (6A), 1097-1110 (2003)
   PUBMED   12743021
REFERENCE   3  (bases 1 to 4607)
  AUTHORS   Abrink,M., Aveskogh,M. and Hellman,L.
  TITLE     Isolation of cDNA clones for 42 different Kruppel-related zinc
            finger proteins expressed in the human monoblast cell line U-937
  JOURNAL   DNA Cell Biol 14 (2), 125-136 (1995)
   PUBMED   7865130
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC021092.1, AK314064.1, AK289843.1 and AC138470.1.
            
            On Nov 23, 2018 this sequence version replaced NM_006630.2.
            
            Transcript Variant: This variant (1) represents the longer
            transcript. Variants 1 and 2 both encode the same protein.
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data because no single transcript was available
            for the full length of the gene. The extent of this transcript is
            supported by transcript alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR1803612.239303.1,
                                           SRR1803617.75103.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA1965299, SAMEA1966682
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000426739.7/ ENSP00000400878.1
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-3                 AC021092.1         34071-34073
            4-62                AK314064.1         1-59
            63-933              AK289843.1         2-872
            934-4607            AC138470.1         126808-130481       c
FEATURES             Location/Qualifiers
     source          1..4607
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="19"
                     /map="19q13.31"
     gene            1..4607
                     /gene="ZNF234"
                     /gene_synonym="HZF4; ZNF269"
                     /note="zinc finger protein 234"
                     /db_xref="GeneID:10780"
                     /db_xref="HGNC:HGNC:13027"
                     /db_xref="MIM:604750"
     exon            1..180
                     /gene="ZNF234"
                     /gene_synonym="HZF4; ZNF269"
                     /inference="alignment:Splign:2.1.0"
     exon            181..234
                     /gene="ZNF234"
                     /gene_synonym="HZF4; ZNF269"
                     /inference="alignment:Splign:2.1.0"
     exon            235..325
                     /gene="ZNF234"
                     /gene_synonym="HZF4; ZNF269"
                     /inference="alignment:Splign:2.1.0"
     CDS             311..2413
                     /gene="ZNF234"
                     /gene_synonym="HZF4; ZNF269"
                     /note="zinc finger protein 269; C2-H2 type zinc finger
                     protein; Homo sapiens zinc finger 234; zinc finger protein
                     234, partial sequence; zinc finger protein 4; zinc finger
                     protein HZF4"
                     /codon_start=1
                     /product="zinc finger protein 234"
                     /protein_id="NP_006621.1"
                     /db_xref="CCDS:CCDS46101.1"
                     /db_xref="GeneID:10780"
                     /db_xref="HGNC:HGNC:13027"
                     /db_xref="MIM:604750"
                     /translation="MTTFKEGLTFKDVAVVFTEEELGLLDPVQRNLYQDVMLENFRNL
                     LSVGHHPFKHDVFLLEKEKKLDIMKTATQRKGKSADKIQSEVETVPEAGRHEELYWGQ
                     IWKQIASDLIKYEDSMISISRFPRQGDLSCQVRAGLYTTHTGQKFYQCDEYKKSFTDV
                     FNFDLHQQLHSGEKSHTCDECGKSFCYISALHIHQRVHMGEKCYKCDVCGKEFSQSSH
                     LQTHQRVHTVEKPFKCVECGKGFSRRSTLTVHCKLHSGEKPYNCEECGRAFIHASHLQ
                     EHQRIHTGEKPFKCDTCGKNFRRRSALNNHCMVHTGEKPYKCEDCGKCFTCSSNLRIH
                     QRVHTGEKPYKCEECGKCFIQPSQFQAHRRIHTGEKPYVCKVCGKGFIYSSSFQAHQG
                     VHTGEKPYKCNECGKSFRMKIHYQVHLVVHTGEKPYKCEVCGKAFRQSSYLKIHLKAH
                     SVQKPFKCEECGQGFNQSSRLQIHQLIHTGEKPYKCEECGKGFSRRADLKIHCRIHTG
                     EKPYNCEECGKVFSQASHLLTHQRVHSGEKPFKCEECGKSFSRSAHLQAHQKVHTGEK
                     PYKCGECGKGFKWSLNLDMHQRVHTGEKPYTCGECGKHFSQASSLQLHQSVHTGEKPY
                     KCDVCGKVFSRSSQLQYHRRVHTGEKPYKCEICGKRFSWRSNLVSHHKIHAAGTFYEN
                     DENSKNIRELSEGGSSTR"
     exon            326..452
                     /gene="ZNF234"
                     /gene_synonym="HZF4; ZNF269"
                     /inference="alignment:Splign:2.1.0"
     exon            453..545
                     /gene="ZNF234"
                     /gene_synonym="HZF4; ZNF269"
                     /inference="alignment:Splign:2.1.0"
     exon            546..4607
                     /gene="ZNF234"
                     /gene_synonym="HZF4; ZNF269"
                     /inference="alignment:Splign:2.1.0"
     regulatory      3261..3266
                     /regulatory_class="polyA_signal_sequence"
                     /gene="ZNF234"
                     /gene_synonym="HZF4; ZNF269"
                     /note="hexamer: AAGAAA"
     regulatory      3274..3279
                     /regulatory_class="polyA_signal_sequence"
                     /gene="ZNF234"
                     /gene_synonym="HZF4; ZNF269"
                     /note="hexamer: AATAAA"
     polyA_site      3289
                     /gene="ZNF234"
                     /gene_synonym="HZF4; ZNF269"
     polyA_site      3297
                     /gene="ZNF234"
                     /gene_synonym="HZF4; ZNF269"
                     /note="major polyA site"
     regulatory      4578..4583
                     /regulatory_class="polyA_signal_sequence"
                     /gene="ZNF234"
                     /gene_synonym="HZF4; ZNF269"
                     /note="hexamer: ATTAAA"
     polyA_site      4607
                     /gene="ZNF234"
                     /gene_synonym="HZF4; ZNF269"
ORIGIN      
        1 agtggagtcg cgggcacttc cgctccaggg aagagggggc gattgtcacg gcacattcca
       61 cggtagtttc ttccagttcc gcgactcgcg ggcccctcct aatgtcaggg acttaagatt
      121 ggggctcgct gggacctggt ggtccggtta tgggaaaaga agcctcgtgg gagagcagag
      181 cctgaaaaag gactgcgcgg actgacttct tggctactga aagcaaagct ccactgttcc
      241 aggcacgatt ctgccttctc tcaaatggca taactcagga ctctgcaaat tcccagaaac
      301 aggaggaaaa atgaccacat tcaaggaggg actgaccttc aaggatgtgg ctgtggtctt
      361 cactgaggag gagctggggc tgctggaccc tgtccagagg aatctgtacc aagatgtgat
      421 gctggagaac ttcaggaacc tgctgtcagt ggggcatcac cccttcaaac atgatgtatt
      481 ccttttagaa aaggaaaaaa agcttgatat aatgaagaca gcaactcaaa gaaaagggaa
      541 atcagcagac aagatccaaa gtgaggtgga gactgttcca gaagcaggac gacatgaaga
      601 gctttactgg gggcaaatct ggaaacagat tgcaagtgat ttaatcaagt atgaagactc
      661 tatgataagt atttctcggt tccccagaca aggtgatttg tcctgccagg ttagggcagg
      721 actatataca actcacacag gacagaaatt ttaccaatgt gatgagtaca aaaaatcctt
      781 cactgatgtc ttcaactttg atcttcatca acagttacac tcaggagaga agtctcatac
      841 atgtgatgag tgtggaaaaa gcttctgtta catctcagcc cttcatattc atcaaagagt
      901 ccacatggga gagaaatgct ataagtgtga cgtgtgtggt aaggaattta gtcagagctc
      961 acatcttcaa actcatcaga gagtccacac tgtagagaaa ccattcaaat gtgtggaatg
     1021 tgggaaaggc ttcagtcgta gatcaacact tactgtacat tgcaaattac actcaggaga
     1081 gaaaccttac aattgtgagg aatgtggaag ggccttcata catgcttccc atcttcagga
     1141 acatcagaga attcatactg gggagaaacc attcaaatgt gatacatgtg gtaagaactt
     1201 ccgtcgtaga tcagcactta ataatcattg catggtccac acaggagaga aaccatacaa
     1261 atgtgaggac tgtggtaagt gtttcacttg tagctcaaac cttcgtatcc atcaaagggt
     1321 ccacacagga gagaaacctt acaagtgtga agaatgtggt aagtgcttta ttcagccttc
     1381 acaatttcag gcccatcgga gaatccacac tggagagaaa ccatacgtat gtaaagtgtg
     1441 tggtaagggt ttcatttaca gttcaagttt tcaggcccat cagggagtcc acactggaga
     1501 gaagccatac aaatgcaatg agtgtgggaa gagcttcaga atgaaaattc attatcaagt
     1561 gcatctggta gtccacacag gggaaaaacc ctataaatgt gaagtatgtg gtaaagcctt
     1621 ccgtcagagt tcatatctta aaatccatct gaaagcacat agtgtacaga aaccttttaa
     1681 gtgtgaagag tgtgggcagg gcttcaatca gagctcacga cttcagattc accagctgat
     1741 ccataccggt gagaaaccat acaaatgtga agagtgcgga aagggattta gtcgtagagc
     1801 agatcttaaa attcattgta ggatccacac aggggagaaa ccatataatt gtgaggagtg
     1861 tgggaaggtc ttcagtcagg cctcgcatct tctaacccat cagagagttc acagtgggga
     1921 aaaaccattt aaatgtgaag agtgtgggaa gagcttcagt cggagtgcac accttcaagc
     1981 ccatcaaaaa gtccacactg gagaaaagcc atacaaatgt ggggagtgtg gaaagggctt
     2041 caagtggagc ttgaaccttg acatgcatca gagggtgcac acaggagaaa aaccctatac
     2101 atgtggggag tgtgggaagc acttcagtca ggcctcaagt ctccaacttc atcagagtgt
     2161 ccacacagga gagaaaccat acaaatgtga tgtatgtggt aaagtcttca gtcggtcttc
     2221 acaattacag tatcataggc gagttcacac tggggaaaaa ccttacaaat gtgagatatg
     2281 tggtaagagg ttcagctggc gatcaaatct tgtaagtcat cacaaaattc atgctgctgg
     2341 tacattttat gaaaatgatg agaatagtaa gaacatcaga gagttgtcag agggaggaag
     2401 ttctacaagg tgattaaaaa aaaaaaaaca gaactcatgt acaacctgaa tgcttgtaat
     2461 tagatttcat aggagggaaa aattttcttt atcaacctct ttgaatttat ttgatttgta
     2521 acgctccaca tttccaccta gacttttttt tgttttttat tttttgtttt gaaacagaat
     2581 ctcgctctgt tgcccatgct ggatgcagtg gtgctatctc agctcactgt aacctccact
     2641 tcccgggttc aagtgattct cctgcctcag tggattacag gtgcacacca ccacgcctgg
     2701 ctaatttttg tatttttagt agagatggag tttcaccata ctggccaggc tggtctcaaa
     2761 ctcctgacct catgtgatcc acccacctcg gcctcccaaa gtgctgggat tacaggcatg
     2821 agccaccgcc cctggcctcc atctagactt tgaaatgatt gccttctaat tacagtagca
     2881 ttctcttatt taaaatattt gttttattta agtcagtgtt taagcaatag ctcagcatat
     2941 cccagtggtc cagtgaccac acagctgaga acccttgtta agtggtacag taaagcattc
     3001 tgtcaaaact ttgacattta tgacatgtta cctaggaaat aggacttaga aaatgagttt
     3061 gacctgggct ttaaaaaagt atactgatga aggtgccaga attgatgtcc attagactgt
     3121 aagctccatg ggggcaggaa ctttgctacc gaatctatac aaccttaaca ttgactagtg
     3181 cttgtaggtg tgctcaatac ttgtttgtta actgaatcaa aaggagtaaa tgcacaatat
     3241 ttgaacattg tatccaaagg aagaaacctg cgaaataaaa ttatttgcag aaatgaacat
     3301 ttgttgaaat gcagaaaacc actggatact gcagcctaca atattaatat gatattactc
     3361 ttttacagtt gacacctgtc ctctctgtag tctcttctct caaatttggt tcttattgag
     3421 agcctgtcta gtttcccaaa ggttttataa aacataagtt gaagtacctt tatttttaat
     3481 tttatttttg agacaggacc tcgctctgtc accgaggctg gagtgcagtg gcataatcat
     3541 ggctcactgc agcctcgtcc tcccaggctc catccatctg cccatctctc cctctgagta
     3601 gctgggacca cgggcacgtg ccaccacacc cagctaattt ttgtatgttt ggtagagaaa
     3661 gggtttcacc acattgccca ggctggtctt gaacacctga gctcaagcaa tccaacctcc
     3721 ttggcctccc agtgttaaat tacaggcgta agccaccaca cccggccaag ttgaagtata
     3781 ttttgtgatt tttctgacag tgcagactga aaaaaattta attaacctga caagagttta
     3841 ctgaatatca cacaattgag tttttaatcc attaatgtta aggcaggggt ttactctaac
     3901 acttttaaag tgtcagaagt agttgccaat gccaaatttt tatcagcccc cttgaattta
     3961 tttgatttct gactttccac atttccatcc agactttgac atgattgccg tctaataact
     4021 gtagcattct cttattaaaa cttctggctg ggtgtggtgg ctcatgcctg taaccccagc
     4081 actttaggag gccaaggcag gtgaatcacc tgaggtcagg acttagagac cagcctgacc
     4141 aacatggtga aaccccatct ctactaaata caaaaattag ctgggcatgg tggcaggcgc
     4201 ctgtaatccc agctactcag gaggctgagg caggaggatt gcttgaaccc gggaggcgga
     4261 agttgcagtg agccgagact gcgccattgc actccagctt gggtgacaga gcaagactcc
     4321 gtctcaaaaa aaaaaaaaaa aacttctgag gtaggggctg taccatattt ttgccccaca
     4381 cccattaagc gaataccaaa aacaacttgt ggaaatttga taattttatc aaatttatta
     4441 tttgggcagg attggcattt accatgcttt tccctattgc tggcagtaaa acatgggttt
     4501 aaggaagagt gtttttcaga atttacactg tatatctctg atttggaagt tatataattg
     4561 gaatttatga ttatgagatt aaaataccaa aaagactaag taacata
//
