LOCUS       NM_014519               1479 bp    mRNA    linear   PRI 22-SEP-2024
DEFINITION  Homo sapiens zinc finger protein 232 (ZNF232), transcript variant
            1, mRNA.
ACCESSION   NM_014519 XM_017025021
VERSION     NM_014519.6
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 1479)
  AUTHORS   Huttlin,E.L., Bruckner,R.J., Navarrete-Perea,J., Cannon,J.R.,
            Baltier,K., Gebreab,F., Gygi,M.P., Thornock,A., Zarraga,G., Tam,S.,
            Szpyt,J., Gassaway,B.M., Panov,A., Parzen,H., Fu,S., Golbazi,A.,
            Maenpaa,E., Stricker,K., Guha Thakurta,S., Zhang,T., Rad,R.,
            Pan,J., Nusinow,D.P., Paulo,J.A., Schweppe,D.K., Vaites,L.P.,
            Harper,J.W. and Gygi,S.P.
  TITLE     Dual proteome-scale networks reveal cell-specific remodeling of the
            human interactome
  JOURNAL   Cell 184 (11), 3022-3040 (2021)
   PUBMED   33961781
REFERENCE   2  (bases 1 to 1479)
  AUTHORS   Haenig,C., Atias,N., Taylor,A.K., Mazza,A., Schaefer,M.H., Russ,J.,
            Riechers,S.P., Jain,S., Coughlin,M., Fontaine,J.F., Freibaum,B.D.,
            Brusendorf,L., Zenkner,M., Porras,P., Stroedicke,M., Schnoegl,S.,
            Arnsburg,K., Boeddrich,A., Pigazzini,L., Heutink,P., Taylor,J.P.,
            Kirstein,J., Andrade-Navarro,M.A., Sharan,R. and Wanker,E.E.
  TITLE     Interactome Mapping Provides a Network of Neurodegenerative Disease
            Proteins and Uncovers Widespread Protein Aggregation in Affected
            Brains
  JOURNAL   Cell Rep 32 (7), 108050 (2020)
   PUBMED   32814053
REFERENCE   3  (bases 1 to 1479)
  AUTHORS   Luck,K., Kim,D.K., Lambourne,L., Spirohn,K., Begg,B.E., Bian,W.,
            Brignall,R., Cafarelli,T., Campos-Laborie,F.J., Charloteaux,B.,
            Choi,D., Cote,A.G., Daley,M., Deimling,S., Desbuleux,A., Dricot,A.,
            Gebbia,M., Hardy,M.F., Kishore,N., Knapp,J.J., Kovacs,I.A.,
            Lemmens,I., Mee,M.W., Mellor,J.C., Pollis,C., Pons,C.,
            Richardson,A.D., Schlabach,S., Teeking,B., Yadav,A., Babor,M.,
            Balcha,D., Basha,O., Bowman-Colin,C., Chin,S.F., Choi,S.G.,
            Colabella,C., Coppin,G., D'Amata,C., De Ridder,D., De Rouck,S.,
            Duran-Frigola,M., Ennajdaoui,H., Goebels,F., Goehring,L., Gopal,A.,
            Haddad,G., Hatchi,E., Helmy,M., Jacob,Y., Kassa,Y., Landini,S.,
            Li,R., van Lieshout,N., MacWilliams,A., Markey,D., Paulson,J.N.,
            Rangarajan,S., Rasla,J., Rayhan,A., Rolland,T., San-Miguel,A.,
            Shen,Y., Sheykhkarimli,D., Sheynkman,G.M., Simonovsky,E., Tasan,M.,
            Tejeda,A., Tropepe,V., Twizere,J.C., Wang,Y., Weatheritt,R.J.,
            Weile,J., Xia,Y., Yang,X., Yeger-Lotem,E., Zhong,Q., Aloy,P.,
            Bader,G.D., De Las Rivas,J., Gaudet,S., Hao,T., Rak,J.,
            Tavernier,J., Hill,D.E., Vidal,M., Roth,F.P. and Calderwood,M.A.
  TITLE     A reference map of the human binary protein interactome
  JOURNAL   Nature 580 (7803), 402-408 (2020)
   PUBMED   32296183
REFERENCE   4  (bases 1 to 1479)
  AUTHORS   Ravasi,T., Suzuki,H., Cannistraci,C.V., Katayama,S., Bajic,V.B.,
            Tan,K., Akalin,A., Schmeier,S., Kanamori-Katayama,M., Bertin,N.,
            Carninci,P., Daub,C.O., Forrest,A.R., Gough,J., Grimmond,S.,
            Han,J.H., Hashimoto,T., Hide,W., Hofmann,O., Kamburov,A., Kaur,M.,
            Kawaji,H., Kubosaki,A., Lassmann,T., van Nimwegen,E.,
            MacPherson,C.R., Ogawa,C., Radovanovic,A., Schwartz,A.,
            Teasdale,R.D., Tegner,J., Lenhard,B., Teichmann,S.A., Arakawa,T.,
            Ninomiya,N., Murakami,K., Tagami,M., Fukuda,S., Imamura,K., Kai,C.,
            Ishihara,R., Kitazume,Y., Kawai,J., Hume,D.A., Ideker,T. and
            Hayashizaki,Y.
  TITLE     An atlas of combinatorial transcriptional regulation in mouse and
            man
  JOURNAL   Cell 140 (5), 744-752 (2010)
   PUBMED   20211142
  REMARK    Erratum:[Cell. 2010 Apr 16;141(2):369. Kamburov, Atanas [added];
            Kaur, Mandeep [added]; MacPherson, Cameron Ross [added];
            Radovanovic, Aleksandar [added]; Schwartz, Ariel [added]]
REFERENCE   5  (bases 1 to 1479)
  AUTHORS   Mavrogiannis,L.A., Argyrokastritis,A., Tzitzikas,N.,
            Dermitzakis,E., Sarafidou,T., Patsalis,P.C. and Moschonas,N.K.
  TITLE     ZNF232: structure and expression analysis of a novel human C(2)H(2)
            zinc finger gene, member of the SCAN/LeR domain subfamily
  JOURNAL   Biochim Biophys Acta 1518 (3), 300-305 (2001)
   PUBMED   11311944
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC012146.25.
            
            On Aug 11, 2021 this sequence version replaced NM_014519.5.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC016039.1, Y15067.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA1965299, SAMEA1966682
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000250076.8/ ENSP00000250076.3
            RefSeq Select criteria :: based on manual assertion, conservation,
                                      expression, longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-79                AC012146.25        69209-69287
            80-554              AC012146.25        71219-71693
            555-681             AC012146.25        72035-72161
            682-1479            AC012146.25        74554-75351
FEATURES             Location/Qualifiers
     source          1..1479
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="17"
                     /map="17p13.2"
     gene            1..1479
                     /gene="ZNF232"
                     /gene_synonym="ZSCAN11"
                     /note="zinc finger protein 232"
                     /db_xref="GeneID:7775"
                     /db_xref="HGNC:HGNC:13026"
                     /db_xref="MIM:616463"
     exon            1..79
                     /gene="ZNF232"
                     /gene_synonym="ZSCAN11"
                     /inference="alignment:Splign:2.1.0"
     CDS             57..1391
                     /gene="ZNF232"
                     /gene_synonym="ZSCAN11"
                     /note="isoform a is encoded by transcript variant 1; zinc
                     finger and SCAN domain-containing protein 11"
                     /codon_start=1
                     /product="zinc finger protein 232 isoform a"
                     /protein_id="NP_055334.2"
                     /db_xref="CCDS:CCDS11068.1"
                     /db_xref="GeneID:7775"
                     /db_xref="HGNC:HGNC:13026"
                     /db_xref="MIM:616463"
                     /translation="MEPPGPVRGPLQDSSWYEPSAELVQTRMAVSLTAAETLALQGTQ
                     GQEKMMMMGPKEEEQSCEYETRLPGNHSTSQEIFRQRFRHLRYQETPGPREALSQLRV
                     LCCEWLRPEKHTKEQILEFLVLEQFLTILPEELQSWVRGHHPKSGEEAVTVLEDLEKG
                     LEPEPQVPGPAHGPAQEEPWEKKESLGAAQEALSIQLQPKETQPFPKSEQVYLHFLSV
                     VTEDGPEPKDKGSLPQPPITEVESQVFSEKLATDTSTFEATSEGTLELQQRNPKAERL
                     RWSPAQEESFRQMVVIHKEIPTGKKDHECSECGKTFIYNSHLVVHQRVHSGEKPYKCS
                     DCGKTFKQSSNLGQHQRIHTGEKPFECNECGKAFRWGAHLVQHQRIHSGEKPYECNEC
                     GKAFSQSSYLSQHRRIHSGEKPFICKECGKAYGWCSELIRHRRVHARKEPSH"
     exon            80..554
                     /gene="ZNF232"
                     /gene_synonym="ZSCAN11"
                     /inference="alignment:Splign:2.1.0"
     exon            555..681
                     /gene="ZNF232"
                     /gene_synonym="ZSCAN11"
                     /inference="alignment:Splign:2.1.0"
     exon            682..1479
                     /gene="ZNF232"
                     /gene_synonym="ZSCAN11"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1457..1462
                     /regulatory_class="polyA_signal_sequence"
                     /gene="ZNF232"
                     /gene_synonym="ZSCAN11"
                     /note="hexamer: CATAAA"
     polyA_site      1479
                     /gene="ZNF232"
                     /gene_synonym="ZSCAN11"
                     /note="major polyA site"
ORIGIN      
        1 gcaaacctgc ccctggggtg agggctgtaa gtggcgcgat tcgcggcagc gccccgatgg
       61 aacctcctgg tcctgtgagg gggcccttgc aagattccag ctggtatgag ccttctgcag
      121 agctagtgca gactaggatg gctgtatcac taacagcagc tgaaactctg gcccttcagg
      181 gtacacaggg acaagagaag atgatgatga tgggaccaaa ggaagaggaa cagtcttgtg
      241 agtatgagac caggctacct gggaaccact ctaccagtca agagatcttc cgccaacgct
      301 tcaggcatct ccgctaccag gagactcctg gtccccggga ggccttgagc caactacgag
      361 tactctgctg tgagtggctg aggccagaga aacacacgaa ggagcagatc ctggagttcc
      421 tggtgctgga acaattcttg accatcctgc ctgaggagct ccaatcctgg gtgcggggac
      481 atcaccctaa gagtggagag gaggctgtga ctgtgctgga ggatttagag aaaggacttg
      541 aaccagagcc gcaggtccca ggccctgcac atggacctgc acaggaagag ccatgggaga
      601 agaaggaatc tctgggagca gcccaggaag cactgagcat ccagctccag cctaaggaga
      661 cccagccttt cccaaagagt gaacaggtat atttacattt tctgtcagtt gttacagaag
      721 atggcccaga gcccaaggac aaaggatcat tgccacaacc acccattact gaagtggaat
      781 cacaggtgtt ctcagaaaaa cttgctactg acacctctac atttgaagct acctctgagg
      841 gtaccttaga actgcagcag agaaatccca aagcggagag actgaggtgg tcccctgccc
      901 aggaggaaag tttcaggcag atggttgtca tccataagga aattcccaca gggaagaaag
      961 accatgaatg tagtgaatgt ggtaaaacct tcatttataa ctcacatctt gttgtccacc
     1021 agagagttca ttctggagag aaaccctata agtgtagtga ctgtgggaaa actttcaaac
     1081 agagctcaaa cctcggtcag catcagagaa ttcatacagg agagaaaccc ttcgaatgta
     1141 atgaatgtgg gaaggccttc agatggggtg ctcatcttgt tcagcatcag aggattcact
     1201 caggagagaa gccctatgag tgtaatgagt gtgggaaggc ctttagtcaa agctcatatc
     1261 taagtcagca tcggagaatt cacagtggag agaaaccttt tatatgtaaa gaatgtggga
     1321 aagcttatgg atggtgctca gagctcatta gacatcggag agttcatgcc agaaaagagc
     1381 cttcccattg aattgaaggg gagaacgtct ccagacagaa ttctacatcg gtctaatcta
     1441 ctttaggact ggatcccata aaagttataa gttccttaa
//
