LOCUS       NM_006385               3773 bp    mRNA    linear   PRI 10-FEB-2024
DEFINITION  Homo sapiens zinc finger protein 211 (ZNF211), transcript variant
            1, mRNA.
ACCESSION   NM_006385
VERSION     NM_006385.5
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 3773)
  AUTHORS   Becker,K.G., Canning,R.D., Nagle,J.W., Dehejia,A.M.,
            Polymeropoulos,M.H., Lee,I.J., Gado,A.M., Biddison,W.E. and
            Drew,P.D.
  TITLE     Molecular cloning and mapping of a novel developmentally regulated
            human C2H2-type zinc finger
  JOURNAL   Mamm Genome 8 (4), 287-289 (1997)
   PUBMED   9096115
REFERENCE   2  (bases 1 to 3773)
  AUTHORS   Becker,K.G., Nagle,J.W., Canning,R.D., Biddison,W.E., Ozato,K. and
            Drew,P.D.
  TITLE     Rapid isolation and characterization of 118 novel C2H2-type zinc
            finger cDNAs expressed in human brain
  JOURNAL   Hum Mol Genet 4 (4), 685-691 (1995)
   PUBMED   7633419
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            DA961612.1, DA745028.1, AK294869.1, AC003682.1 and BQ678885.1.
            This sequence is a reference standard in the RefSeqGene project.
            
            On Nov 23, 2018 this sequence version replaced NM_006385.4.
            
            Summary: This gene encodes a protein containing a
            Kruppel-associated box domain and multiple zinc finger domains.
            This protein may play a role in developmental processes.
            Alternative splicing results in multiple transcript variants.
            [provided by RefSeq, Mar 2014].
            
            Transcript Variant: This variant (1) encodes isoform 1.
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR1803613.189741.1,
                                           SRR1660805.83539.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA1965299, SAMEA1966682
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000240731.5/ ENSP00000240731.4
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-34                DA961612.1         2-35
            35-606              DA745028.1         1-572
            607-2415            AK294869.1         568-2376
            2416-2511           AK294869.1         2378-2473
            2512-3069           AC003682.1         131492-132049
            3070-3773           BQ678885.1         1-704
FEATURES             Location/Qualifiers
     source          1..3773
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="19"
                     /map="19q13.43"
     gene            1..3773
                     /gene="ZNF211"
                     /gene_synonym="C2H2-25; CH2H2-25; ZNF-25"
                     /note="zinc finger protein 211"
                     /db_xref="GeneID:10520"
                     /db_xref="HGNC:HGNC:13003"
                     /db_xref="MIM:601856"
     exon            1..269
                     /gene="ZNF211"
                     /gene_synonym="C2H2-25; CH2H2-25; ZNF-25"
                     /inference="alignment:Splign:2.1.0"
     CDS             180..1913
                     /gene="ZNF211"
                     /gene_synonym="C2H2-25; CH2H2-25; ZNF-25"
                     /note="isoform 1 is encoded by transcript variant 1; zinc
                     finger protein C2H2-25"
                     /codon_start=1
                     /product="zinc finger protein 211 isoform 1"
                     /protein_id="NP_006376.2"
                     /db_xref="CCDS:CCDS12956.1"
                     /db_xref="GeneID:10520"
                     /db_xref="HGNC:HGNC:13003"
                     /db_xref="MIM:601856"
                     /translation="MLGFPPGRPQLPVQLRPQTRMATALRDPASVPIATEVLFKLTQG
                     SVTFEDVAVYFSWEEWDLLDEAQKHLYFDVMLENFALTSSLGCWCGVEHEETPSEQRI
                     SGERVPQFRTSKEGSSSQNADSCEICCLVLRDILHLAEHQGTNCGQKLHTCGKQFYIS
                     ANLQQHQRQHITEAPFRSYVDTASFTQSCIVHVSEKPFTCREIRKDFLANMRFLHQDA
                     TQTGEKPNNSNKCAVAFYSGKSHHNWGKCSKAFSHIDTLVQDQRILTREGLFECSKCG
                     KACTRRCNLIQHQKVHSEERPYECNECGKFFTYYSSFIIHQRVHTGERPYACPECGKS
                     FSQIYSLNSHRKVHTGERPYECGECGKSFSQRSNLMQHRRVHTGERPYECSECGKSFS
                     QNFSLIYHQRVHTGERPHECNECGKSFSRSSSLIHHRRLHTGERPYECSKCGKSFKQS
                     SSFSSHRKVHTGERPYVCGECGKSFSHSSNLKNHQRVHTGERPVECSECSKSFSCKSN
                     LIKHLRVHTGERPYECSECGKSFSQSSSLIQHRRVHTGKRPYQCSQCGKSFGCKSVLI
                     QHQRVHIGEKP"
     exon            270..308
                     /gene="ZNF211"
                     /gene_synonym="C2H2-25; CH2H2-25; ZNF-25"
                     /inference="alignment:Splign:2.1.0"
     exon            309..435
                     /gene="ZNF211"
                     /gene_synonym="C2H2-25; CH2H2-25; ZNF-25"
                     /inference="alignment:Splign:2.1.0"
     exon            436..3773
                     /gene="ZNF211"
                     /gene_synonym="C2H2-25; CH2H2-25; ZNF-25"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2476..2481
                     /regulatory_class="polyA_signal_sequence"
                     /gene="ZNF211"
                     /gene_synonym="C2H2-25; CH2H2-25; ZNF-25"
                     /note="hexamer: AATAAA"
     polyA_site      2500
                     /gene="ZNF211"
                     /gene_synonym="C2H2-25; CH2H2-25; ZNF-25"
                     /note="major polyA site"
     regulatory      3753..3758
                     /regulatory_class="polyA_signal_sequence"
                     /gene="ZNF211"
                     /gene_synonym="C2H2-25; CH2H2-25; ZNF-25"
                     /note="hexamer: AATAAA"
     polyA_site      3773
                     /gene="ZNF211"
                     /gene_synonym="C2H2-25; CH2H2-25; ZNF-25"
                     /note="major polyA site"
ORIGIN      
        1 agggcgggac ttgtggcgtc ttcgcagcgg tcattttggc tgccctcccg gaggtccgtt
       61 ctgtctgtca gccgctttgg tacgctgcat cgggatcgaa gtgacggacc gtgaaggcgc
      121 gagagtcagg tctgagggtc gggggcagag ccgcccgcga ggccggcctg gggatagcga
      181 tgctcgggtt ccccccgggt cgcccgcagc tcccggtcca gctccgccca cagactcgga
      241 tggcgaccgc actgagggac ccggcttcgg ttcccatagc tacagaggtg cttttcaaac
      301 ttacacaggg aagtgtgacc tttgaagatg tggccgtgta cttctcctgg gaggaatggg
      361 atctccttga tgaggctcag aaacacctgt acttcgatgt gatgctggag aactttgcac
      421 ttacgtcctc cctgggttgt tggtgtggag tggaacatga ggaaacacct tctgaacaga
      481 gaatttctgg agaaagagtg ccacagttca ggacttccaa agaaggttca tcttcccaga
      541 atgccgactc ctgtgaaata tgttgcctgg tcttgagaga tattttgcac ttggctgaac
      601 accaaggaac aaactgcggg cagaaactac acacatgtgg aaaacaattc tacatcagtg
      661 caaatcttca acagcaccag aggcagcaca ttacagaggc acctttcaga agttatgtgg
      721 acactgcctc gtttacacag agttgcatag tccatgtgtc ggagaaaccc tttacctgca
      781 gggagatcag gaaagacttc ctggccaaca tgaggtttct ccatcaagac gccactcaaa
      841 caggggagaa gccaaataac agtaacaagt gtgcggtggc cttttacagt ggaaaaagtc
      901 atcacaactg gggaaaatgc agtaaagcct ttagccacat agacacactt gttcaggacc
      961 agagaatcct cactagagaa ggactttttg agtgcagtaa atgtgggaaa gcatgtacgc
     1021 gaagatgtaa cctcattcag caccagaaag tccacagtga agaaaggcct tatgaatgca
     1081 atgaatgtgg aaaattcttt acctactact ccagtttcat tatacatcag agagttcata
     1141 ctggagaaag gccttatgcg tgccctgaat gtgggaaatc gtttagtcag atatacagcc
     1201 tcaatagcca taggaaagtt cacactggag aaaggcctta tgaatgtggg gaatgtggga
     1261 aatcttttag ccaaaggtcc aacctcatgc agcatcgcag agttcacact ggagaaaggc
     1321 cttatgaatg cagcgaatgt gggaaatctt ttagccaaaa ctttagcctg atctaccacc
     1381 agagagttca cactggagaa agacctcatg agtgcaatga atgtggaaaa tcctttagcc
     1441 gaagctccag cctcattcac caccggagac ttcacactgg agaaagaccc tatgagtgca
     1501 gtaaatgtgg gaagtcattt aagcaaagct ccagcttcag ttcacatcgg aaagtccaca
     1561 caggggaaag gccttatgtg tgtggggaat gtgggaaatc ctttagccat agctccaacc
     1621 ttaagaacca ccagagagtt cacactggag aaagacctgt tgagtgcagt gaatgtagca
     1681 aatcctttag ctgtaaatct aacctcatta aacacctgag agttcacact ggagaaaggc
     1741 cttatgagtg cagtgaatgt gggaaatcct ttagccaaag ttctagcctc attcaacacc
     1801 gcagagttca cacgggaaaa aggccttatc agtgcagtca atgtgggaaa tcctttggct
     1861 gcaaatctgt cctcattcaa caccagagag ttcacattgg agaaaagcct tagctgtact
     1921 gagaatatgc aatttccttt tagtgtaatt atactgaagg agtacacctg tgagagagac
     1981 aagtacctga tttggaagcc ccaacatcta aggatataca gtgggcggat tccccttaag
     2041 ttccaggtat gtgttacact ttctaacatg ccatttagaa agtgttagac tttctcacct
     2101 gccatttatg gctcttgccg tttatgtcac tgacagtttc tgaggcagaa gccgtatcat
     2161 gtctaccacc tgtgaggtcc acacagtgtg tatcatttac ctcctgaacc tgctcaagga
     2221 agcagacctc tgcttctccc catttgctag aagaaatcat gaatagtctg agtcttcctc
     2281 tctgacaagt tagggcatgg acttgaccca gctttgtgcc agagaaccca atatgagtgt
     2341 tgttggcagc ttgccaagaa ggactgtctt tttcaagaca tactggtttc atgtgacacc
     2401 tccatggatt tttttccagc ctctaagtca ccaacttggg aactgcttgt ctcacgttgc
     2461 tttgtttttt acaataataa aagcattatt atttaagcta cctttatctt ggcatttgat
     2521 tcactctttg aggtggttca aaaacagaat cgggccctgc cagctttaca gagtaaacac
     2581 ctttggaggg agagggaggt gtcatatgcc tcagtgacaa cagtataatg gaaaaataca
     2641 actgtctttc cagctttggc ctaatctgaa tttgaattat tgcccaaggc cttctaggaa
     2701 atactgcagg atattatggt cttaattcgt ggactggatg caaggatttt ttgtgggctc
     2761 aaaggacacc ctgaggaagt gggaaattgt gacaaattcc attgcttctg ggaacaagat
     2821 gaattttgtt gttattcaca agggttatta catactgccc agcactgttg aggcagtcta
     2881 cccccagtgc tgccaaggag ccaagtgccc caatacaatt tagtaggcta ctgtcactgt
     2941 aaaatgatgg gggaaccata attggtgtgg aaacactggg ttactaggga gtgaaggaga
     3001 ctgcagcaaa ctagatggaa tgtgctcctt gtaatatgtt ctagtaattg tgcaggatca
     3061 gtgtgtacag acattcttag aatttccagg catgtgtatt ttttgtagct gaggtgactg
     3121 tcaaaaaata ataaacaacc taaaggtttt gtgtattcca atagcctttc tgggatgtgc
     3181 acctcaagaa cattgctgca taggccagga aaacaagcat agaaagaagg ggcgggggat
     3241 gtccttccag gaatgtgact ttgtaaccta ccatcatcct gtgtttaaat gaattcaaat
     3301 cagtttcatt gattaccagt atttgctgcc cactgaggca aggtgtccct ccaaggtcat
     3361 caggaaagag agttaatgta gggttaccaa acctagtcaa aaacacatta taccatcatt
     3421 ataattatta caatgaacat atcagtcacc tcggatttac ctcaggcctt tttctaagct
     3481 ctccctcccc tctctggccc tcaaggcaac cattgattta taccttcatt tataataggt
     3541 ttgtttgtat tttctataat atatgatttt attaataaaa tgtctttttt tccagtttca
     3601 ttcatgatgc ataattattt tgagattctt caatggagct tatatgtggt ggtcattctt
     3661 tttattgctg agtggtatat tttttatgga tatactattt gttatccatt tgtttataag
     3721 catttaggtt ttatctagtt ttggctatta caaataaagc tgctagaaat gta
//
