LOCUS       NM_001098507           13740 bp    mRNA    linear   PRI 12-FEB-2025
DEFINITION  Homo sapiens zinc finger protein 207 (ZNF207), transcript variant
            3, mRNA.
ACCESSION   NM_001098507
VERSION     NM_001098507.2
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 13740)
  AUTHORS   Perlee,S., Kikuchi,S., Nakadai,T., Masuda,T., Ohtsuki,S.,
            Matsumoto,M., Rahmutulla,B., Fukuyo,M., Cifani,P., Kentsis,A.,
            Roeder,R.G., Kaneda,A. and Hoshii,T.
  TITLE     SETD1A function in leukemia is mediated through interaction with
            mitotic regulators BuGZ/BUB3
  JOURNAL   EMBO Rep 24 (10), e57108 (2023)
   PUBMED   37535603
  REMARK    GeneRIF: SETD1A function in leukemia is mediated through
            interaction with mitotic regulators BuGZ/BUB3.
REFERENCE   2  (bases 1 to 13740)
  AUTHORS   Wang,X., Zhou,T., Chen,X., Wang,Y., Ding,Y., Tu,H., Gao,S.,
            Wang,H., Tang,X. and Yang,Y.
  TITLE     System analysis based on the cancer-immunity cycle identifies
            ZNF207 as a novel immunotherapy target for hepatocellular carcinoma
  JOURNAL   J Immunother Cancer 10 (3) (2022)
   PUBMED   35246476
  REMARK    GeneRIF: System analysis based on the cancer-immunity cycle
            identifies ZNF207 as a novel immunotherapy target for
            hepatocellular carcinoma.
REFERENCE   3  (bases 1 to 13740)
  AUTHORS   Huttlin,E.L., Bruckner,R.J., Navarrete-Perea,J., Cannon,J.R.,
            Baltier,K., Gebreab,F., Gygi,M.P., Thornock,A., Zarraga,G., Tam,S.,
            Szpyt,J., Gassaway,B.M., Panov,A., Parzen,H., Fu,S., Golbazi,A.,
            Maenpaa,E., Stricker,K., Guha Thakurta,S., Zhang,T., Rad,R.,
            Pan,J., Nusinow,D.P., Paulo,J.A., Schweppe,D.K., Vaites,L.P.,
            Harper,J.W. and Gygi,S.P.
  TITLE     Dual proteome-scale networks reveal cell-specific remodeling of the
            human interactome
  JOURNAL   Cell 184 (11), 3022-3040 (2021)
   PUBMED   33961781
REFERENCE   4  (bases 1 to 13740)
  AUTHORS   Shirnekhi,H.K., Herman,J.A., Paddison,P.J. and DeLuca,J.G.
  TITLE     BuGZ facilitates loading of spindle assembly checkpoint proteins to
            kinetochores in early mitosis
  JOURNAL   J Biol Chem 295 (43), 14666-14677 (2020)
   PUBMED   32820050
  REMARK    GeneRIF: BuGZ facilitates loading of spindle assembly checkpoint
            proteins to kinetochores in early mitosis.
REFERENCE   5  (bases 1 to 13740)
  AUTHORS   Zhou,C. and Li,N.
  TITLE     [Expression of ZNF207 in hepatocellular carcinoma and its
            significance]
  JOURNAL   Zhong Nan Da Xue Xue Bao Yi Xue Ban 44 (4), 406-412 (2019)
   PUBMED   31113916
  REMARK    GeneRIF: ZNF207 expression is elevated in hepatocellular carcinoma
REFERENCE   6  (bases 1 to 13740)
  AUTHORS   Baltz,A.G., Munschauer,M., Schwanhausser,B., Vasile,A.,
            Murakawa,Y., Schueler,M., Youngs,N., Penfold-Brown,D., Drew,K.,
            Milek,M., Wyler,E., Bonneau,R., Selbach,M., Dieterich,C. and
            Landthaler,M.
  TITLE     The mRNA-bound proteome and its global occupancy profile on
            protein-coding transcripts
  JOURNAL   Mol Cell 46 (5), 674-690 (2012)
   PUBMED   22681889
REFERENCE   7  (bases 1 to 13740)
  AUTHORS   Hegele,A., Kamburov,A., Grossmann,A., Sourlis,C., Wowro,S.,
            Weimann,M., Will,C.L., Pena,V., Luhrmann,R. and Stelzl,U.
  TITLE     Dynamic protein-protein interaction wiring of the human spliceosome
  JOURNAL   Mol Cell 45 (4), 567-580 (2012)
   PUBMED   22365833
REFERENCE   8  (bases 1 to 13740)
  AUTHORS   Wang,J., Huo,K., Ma,L., Tang,L., Li,D., Huang,X., Yuan,Y., Li,C.,
            Wang,W., Guan,W., Chen,H., Jin,C., Wei,J., Zhang,W., Yang,Y.,
            Liu,Q., Zhou,Y., Zhang,C., Wu,Z., Xu,W., Zhang,Y., Liu,T., Yu,D.,
            Zhang,Y., Chen,L., Zhu,D., Zhong,X., Kang,L., Gan,X., Yu,X., Ma,Q.,
            Yan,J., Zhou,L., Liu,Z., Zhu,Y., Zhou,T., He,F. and Yang,X.
  TITLE     Toward an understanding of the protein interaction network of the
            human liver
  JOURNAL   Mol Syst Biol 7, 536 (2011)
   PUBMED   21988832
  REMARK    Erratum:[Mol Syst Biol. 2017 Dec 18;13(12):965. doi:
            10.15252/msb.20178107.. PMID: 29254952]
            Publication Status: Online-Only
REFERENCE   9  (bases 1 to 13740)
  AUTHORS   Andersen,J.S., Lam,Y.W., Leung,A.K., Ong,S.E., Lyon,C.E.,
            Lamond,A.I. and Mann,M.
  TITLE     Nucleolar proteome dynamics
  JOURNAL   Nature 433 (7021), 77-83 (2005)
   PUBMED   15635413
REFERENCE   10 (bases 1 to 13740)
  AUTHORS   Pahl,P.M., Hodges,Y.K., Meltesen,L., Perryman,M.B., Horwitz,K.B.
            and Horwitz,L.D.
  TITLE     ZNF207, a ubiquitously expressed zinc finger gene on chromosome
            6p21.3
  JOURNAL   Genomics 53 (3), 410-412 (1998)
   PUBMED   9799612
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BC002372.2, AK226172.1, AI308956.1 and AC005899.1.
            
            On May 20, 2020 this sequence version replaced NM_001098507.1.
            
            Transcript Variant: This variant (3) represents the longest
            transcript and encodes the longest isoform (c).
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR14038195.355903.1,
                                           SRR14038193.3028363.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA1965299, SAMEA1966682
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000394670.9/ ENSP00000378165.4
            RefSeq Select criteria :: based on manual assertion, conservation,
                                      expression, longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-8                 BC002372.2         20-27
            9-2191              AK226172.1         1-2183
            2192-2304           AI308956.1         11-123              c
            2305-13740          AC005899.1         80091-91526
FEATURES             Location/Qualifiers
     source          1..13740
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="17"
                     /map="17q11.2"
     gene            1..13740
                     /gene="ZNF207"
                     /gene_synonym="BuGZ; hBuGZ"
                     /note="zinc finger protein 207"
                     /db_xref="GeneID:7756"
                     /db_xref="HGNC:HGNC:12998"
                     /db_xref="MIM:603428"
     exon            1..170
                     /gene="ZNF207"
                     /gene_synonym="BuGZ; hBuGZ"
                     /inference="alignment:Splign:2.1.0"
     CDS             130..1614
                     /gene="ZNF207"
                     /gene_synonym="BuGZ; hBuGZ"
                     /note="isoform c is encoded by transcript variant 3;
                     BUB3-interacting and GLEBS motif-containing protein
                     ZNF207"
                     /codon_start=1
                     /product="BUB3-interacting and GLEBS motif-containing
                     protein ZNF207 isoform c"
                     /protein_id="NP_001091977.1"
                     /db_xref="CCDS:CCDS42294.1"
                     /db_xref="GeneID:7756"
                     /db_xref="HGNC:HGNC:12998"
                     /db_xref="MIM:603428"
                     /translation="MGRKKKKQLKPWCWYCNRDFDDEKILIQHQKAKHFKCHICHKKL
                     YTGPGLAIHCMQVHKETIDAVPNAIPGRTDIELEIYGMEGIPEKDMDERRRLLEQKTQ
                     ESQKKKQQDDSDEYDDDDSAASTSFQPQPVQPQQGYIPPMAQPGLPPVPGAPGMPPGI
                     PPLMPGVPPLMPGMPPVMPGMPPGLHHQRKYTQSFCGENIMMPMGGMMPPGPGIPPLM
                     PGMPPGMPPPVPRPGIPPMTQAQAVSAPGILNRPPAPTATVPAPQPPVTKPLFPSAGQ
                     MGTPVTSSSTASSNSESLSASSKALFPSTAQAQAAVQGPVGTDFKPLNSTPATTTEPP
                     KPTFPAYTQSTASTTSTTNSTAAKPAASITSKPATLTTTSATSKLIHPDEDISLEERR
                     AQLPKYQRNLPRPGQAPIGNPPVGPIGGMMPPQPGIPQQQGMRPPMPPHGQYGGHHQG
                     MPGYLPGAMPPYGQGPPMVPPYQGGPPRPPMGMRPPVMSQGGRY"
     exon            171..297
                     /gene="ZNF207"
                     /gene_synonym="BuGZ; hBuGZ"
                     /inference="alignment:Splign:2.1.0"
     exon            298..436
                     /gene="ZNF207"
                     /gene_synonym="BuGZ; hBuGZ"
                     /inference="alignment:Splign:2.1.0"
     exon            437..604
                     /gene="ZNF207"
                     /gene_synonym="BuGZ; hBuGZ"
                     /inference="alignment:Splign:2.1.0"
     exon            605..680
                     /gene="ZNF207"
                     /gene_synonym="BuGZ; hBuGZ"
                     /inference="alignment:Splign:2.1.0"
     exon            681..728
                     /gene="ZNF207"
                     /gene_synonym="BuGZ; hBuGZ"
                     /inference="alignment:Splign:2.1.0"
     exon            729..799
                     /gene="ZNF207"
                     /gene_synonym="BuGZ; hBuGZ"
                     /inference="alignment:Splign:2.1.0"
     exon            800..957
                     /gene="ZNF207"
                     /gene_synonym="BuGZ; hBuGZ"
                     /inference="alignment:Splign:2.1.0"
     exon            958..1050
                     /gene="ZNF207"
                     /gene_synonym="BuGZ; hBuGZ"
                     /inference="alignment:Splign:2.1.0"
     exon            1051..1293
                     /gene="ZNF207"
                     /gene_synonym="BuGZ; hBuGZ"
                     /inference="alignment:Splign:2.1.0"
     exon            1294..1453
                     /gene="ZNF207"
                     /gene_synonym="BuGZ; hBuGZ"
                     /inference="alignment:Splign:2.1.0"
     exon            1454..13740
                     /gene="ZNF207"
                     /gene_synonym="BuGZ; hBuGZ"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2179..2184
                     /regulatory_class="polyA_signal_sequence"
                     /gene="ZNF207"
                     /gene_synonym="BuGZ; hBuGZ"
                     /note="hexamer: AATAAA"
     polyA_site      2196
                     /gene="ZNF207"
                     /gene_synonym="BuGZ; hBuGZ"
                     /note="major polyA site"
     regulatory      2280..2285
                     /regulatory_class="polyA_signal_sequence"
                     /gene="ZNF207"
                     /gene_synonym="BuGZ; hBuGZ"
                     /note="hexamer: AATAAA"
     polyA_site      2304
                     /gene="ZNF207"
                     /gene_synonym="BuGZ; hBuGZ"
     regulatory      12208..12213
                     /regulatory_class="polyA_signal_sequence"
                     /gene="ZNF207"
                     /gene_synonym="BuGZ; hBuGZ"
                     /note="hexamer: ATTAAA"
     polyA_site      12228
                     /gene="ZNF207"
                     /gene_synonym="BuGZ; hBuGZ"
     regulatory      13178..13183
                     /regulatory_class="polyA_signal_sequence"
                     /gene="ZNF207"
                     /gene_synonym="BuGZ; hBuGZ"
                     /note="hexamer: ATTAAA"
     polyA_site      13198
                     /gene="ZNF207"
                     /gene_synonym="BuGZ; hBuGZ"
     regulatory      13716..13721
                     /regulatory_class="polyA_signal_sequence"
                     /gene="ZNF207"
                     /gene_synonym="BuGZ; hBuGZ"
                     /note="hexamer: AATAAA"
     polyA_site      13740
                     /gene="ZNF207"
                     /gene_synonym="BuGZ; hBuGZ"
ORIGIN      
        1 gtcggccatt ttgtgtctgc ttcctgtggg acgtggtggt agccgttggg ttgggaaagt
       61 gagggatttt tggcctcgtt tctcctgctt cttttctcct cccttttact ttgccggtag
      121 aacacagtta tgggtcgcaa gaagaagaag cagctgaagc cgtggtgctg gtattgtaat
      181 agagattttg atgatgagaa gatccttatt cagcaccaaa aagcaaagca ttttaaatgc
      241 catatatgtc acaagaaatt gtatacagga cctggcttag ctattcattg catgcaggta
      301 cataaagaaa caatagatgc cgtaccaaat gcaatacctg gaagaacaga catagagttg
      361 gaaatatatg gtatggaagg tattccagaa aaagacatgg atgaaagacg acgacttctt
      421 gaacagaaaa cacaagaaag tcaaaaaaag aagcaacaag atgattctga tgaatatgat
      481 gatgacgact ctgcagcctc aacttcattt cagccacagc ctgttcaacc tcagcaaggt
      541 tatattcctc caatggcaca gccaggactg ccaccagtac caggagcacc aggaatgcct
      601 ccaggcatac ctccattaat gccaggtgtt cctcctctga tgccaggaat gccaccagtt
      661 atgccaggca tgccacctgg attgcatcat cagagaaaat acacccagtc attttgcggt
      721 gaaaacataa tgatgccaat gggtggaatg atgccacctg gaccaggaat accacctctg
      781 atgcctggaa tgccaccagg tatgccccca cctgttccac gtcctggaat tcctccaatg
      841 actcaagcac aggctgtttc agcgccaggt attcttaata gaccacctgc accaacagca
      901 actgtacctg ccccacagcc tccagttact aagcctcttt tccccagtgc tggacagatg
      961 gggacacctg tcacaagctc aagtacagct tcatccaatt cagaaagtct gtctgcatct
     1021 tctaaagctc tgtttcctag cacagcacaa gctcaggcag ctgtccaagg acctgttggt
     1081 acagatttca aacccttaaa tagtacccct gcaacaacta cagaaccccc aaagcctaca
     1141 ttccctgctt atacacagtc tacagcttca acaactagta caacaaatag tactgcagct
     1201 aaaccagcgg cttcaataac aagtaagcct gctacactta caacaactag tgcaaccagt
     1261 aagttgatcc atccagatga ggatatatcc ctggaagaga gaagggcaca gttacctaag
     1321 tatcaacgta atcttcctcg gccaggacag gcccccatcg gtaatccacc agttggacca
     1381 attggaggta tgatgccacc acagccaggc atcccacagc aacaaggaat gagaccccca
     1441 atgccacctc atggtcagta tggtggtcat catcaaggca tgccaggata ccttcctggt
     1501 gctatgcccc cgtatgggca gggaccgcca atggtgcccc cttaccaggg tgggcctcct
     1561 cgacctccga tgggaatgag acctcctgta atgtcgcaag gtggccgtta ctgatcttac
     1621 ttcatccagt ctaataggtt tggagattaa accttttctc aacttgtgct gtttatatag
     1681 ccaagcttcc gtcaataagg cttcattgtg actttaacaa acattatctt cccacatacc
     1741 aggaactatt ggacatttat tttacatggg aaaaattatt tggaataata aagcaggaac
     1801 ttttcctgaa gttgcaattt atactgtatg gcttcttttt catgtttcat ctaggttttt
     1861 agaagtgaag tatagtaaat ttggttcgtt aaattgtgaa ggcgctggaa ttacatgaac
     1921 ataccaccct agtaaaggca agttctgtaa gcttacattg ctatttgtaa agtttgcctt
     1981 cacagcattt cagatgctgt tggacttcat gtccccaacc tagcttggtg agggctgtaa
     2041 ctgtttccaa gtacttgtac attggaagtc tgaatgtgta acaatattta atgtatttag
     2101 agttcctcat gttgcagggt ttaagaaatc tgacccacca aggtcatgtg acttttctgt
     2161 actgttaaac ttcattgtaa taaaatgaga gaaaaattta tgccttttta ttcataaccc
     2221 agctgtggac cactgcctga aaggtttgta cagatgcatg ccacagtaga tgtccacata
     2281 ataaaattca tagttaccaa tgcagttttg atatatcatt ggattctgtc tttgagttgt
     2341 aggttatttc ttagctgcat gttttaaact gaatttgcat agagttgtat gttaatgttt
     2401 cagttaagag aaaaacttaa gatacatgag tcattacata atgggtatga aatctttata
     2461 atcacccttc caccctctat ggtgtcagta cacatcacgt gtcatagata cttaaaatgt
     2521 aaatgttaac acttttcctt cctgctgaga tgtttagagc ctagtgccag acccattcat
     2581 ttccttttga ttatttttga gactcagtac tgcatggacc tcagaagctt ttcaggtgca
     2641 aacttctaga agcttaggtg catgcagtaa tagcttcttg tgctgttaat gggttattat
     2701 atattattct aagtgtaatg ctgagaatct aaatgtgtct ctgttgggat ggttaacaga
     2761 tgaattggca atttttatta tgttcctgga agattacatt attcatttga gtaccttctg
     2821 ttattaagcc taggtagcct tactgtgcaa ctttttattt atccttggaa attttgaatg
     2881 ttgtgttctt acagagagct tttctgtaga gatgactgct attcaatatt ttgtgttgca
     2941 acctcttaaa ataatagctc ttgttgacct ttttgggatc tgtttttctg atcttttgca
     3001 gggtagtttt atgatttttt aggcatcaaa taacctatgc aaagtattaa tataatgaac
     3061 tcaagttgag tttttctcat tataaagtta agacttctaa gaaaatggta acatttcttt
     3121 ataactttcc tgtgaaggta tagataaaac acatgaagtc tgaagttgta tggaaaaaag
     3181 ggctttaact ttgaaggaaa atatattgaa aagtgattta gccatcacaa aagagttcgt
     3241 atttatgtga cagatgaaag tcataccttt aagcaaaaca ttgcaagtat tataaagctg
     3301 aatgctattt taactcacat tggctgggtg cagtggctca cgcctgtaat cccagccctc
     3361 tggaaggctg agatgggagg attgcttgag tccaggagtt tgagaccagc ctggccaaca
     3421 tggcaaaacc ccatctgtac aaaacattta aaaattagcc aggcgcgtta gtgtgtgtct
     3481 gtggtcccag ctgctcaaga ggctgaggaa ggaggttctt cctccttccg aggctgcggt
     3541 gagctatgtt cactccagcc tgggcaacag agcgagactc tgtcaaaaaa taaattaaaa
     3601 tatctgatta tctggcttca atgattttgg ctcctgtgct tgtggtacca tagtggtaca
     3661 aaaattttca tagtttgaaa ataaaacagg tattttgcca gtaatgtatt tctttctgcc
     3721 agcagccaag tcccaaacca ctttcccctc tgaacctctg cttacctaaa tggtttcaaa
     3781 attaatacat gctgctttga tttggcagca cacttaatat actgctgaag gaaaacttgt
     3841 gttgaaagtc tttaagataa aaatggtgtg ataggccggg cgcagtggct cacgcctgta
     3901 atcccagcac tttgggaggc ccaggcgggt ggatcatgag gtcaggagat ggagaccatc
     3961 ctggctaaca cggtgaaacc ccgtttctac taaaaataca aaaaattagc tgggcgtagt
     4021 tgcggatgcc tgtagtccca actactctgg agaccgaggc aggagaatgg cgtgaacccg
     4081 ggaggcatag cttgcagtga gcggagatca caccactgca ctctagcctg gacgacagat
     4141 tgagactccg tctcaaaaaa aaaaaatgct gtgattaaat ttagaataat taagtaaggg
     4201 gtgctctccc aaattctcag gaatttcatg tatacggtta ttgacaaact gcaatagggt
     4261 tagtagacct gtttcagaaa ttatgtgaag ctttatttgc attttatgca aagaaggttg
     4321 atactttgta gcaaggtttt ttgctctctg tataggtctg atgggcaaaa atggaacttt
     4381 taaatatggg atagaattct aattaaaaat taattgaaag tgttaggcat tggcagataa
     4441 aacttaagct catgagttcc tgagtttgta gctataggct cagaggtggt gtacccattt
     4501 aatatatttg aagtgtaatt tttgcatgca tccaaacgta attaagcttc tagaaaatac
     4561 cttttttcta aatgcttctg gggtccatag tgtggttgaa ttatgagtgg agcaaattat
     4621 attcatataa ttaactctga ctcaaccttc cttaagtagt agatgaagtt gagtcaaagt
     4681 ggatgccaac tgccctcaca gaagacaact tttgggactt gataattcag gcaggcattg
     4741 tgattgtcat aattaaggaa gctgtaaggt tagtagggct ggcaactttg gctctacctt
     4801 acatccaccc cttttagaaa aacaagaaaa cattttgtct ggcactagtt tctgttgtat
     4861 aagttttcat actgtttaac aagaccacag caggtaagga ttaatttttg agtggctgct
     4921 ggaattactt gatttgaata cttagtattt tagtagtgtc tcacacattt gccattaggt
     4981 atgaataaaa tattcctact gtactcctat tccactaagt tacattttga acttagactc
     5041 accttaatta aacttaatta attggggagg gggattcccc aacaaaaaga agtacgggct
     5101 cagagtggaa ttgtagtgga caatagttaa aaacaaagct gctccttttg cttgcttgat
     5161 cattgggatt tttaaaaaaa aaaattttaa tgcatgtctt ttaaattaat tgggaactgt
     5221 ttttctaaaa ttaaaatttt cttcttccta tagccctgcc ataggacagg ctgaggctga
     5281 gtctcagtgt tgccctgttc agtctgaggc aagtgggatt tattttattc cttatagggg
     5341 ctttcacagc tttatggctg ttggatattt atgtccccaa acttgcagca agtttggtga
     5401 aggcccctaa atttaattaa acttaggatt tttatactct tttggcagag aaggctctat
     5461 attaatattc acgtttgact gtggtgttaa taaacataag tatttcatat gcaattttat
     5521 gtaatttgct gtgtgttaca taattaacag cttcagtaaa gcttgtgttc ctatattgaa
     5581 cttcaataaa ttgacaaaat ttgatatttt tgattggagg caagaaatgt ttcattcaag
     5641 ttttttactt tcacttctag gaaaatctta ctggttttat tttctccata aactattaaa
     5701 tttaacctca aggataagtt taatcattgg aaatgccact ggatactgaa atgtgccttc
     5761 tcttttttga gacggagttt cactcttatc acccaggatg gagtgcagtg gtgcgatctc
     5821 ggttcactgc aacctctgcc tcccggattc aagtgattct cctgcctcag cctcccgagt
     5881 agctgggatt ataggctccc gccaccacat ctggctattt tttcaatatt tttcagtagg
     5941 gatggggttt tgccgtgttg gccaggctgg tctcaaactc ctgacctcag gtgatccacc
     6001 catctcagcc tcccagagtg ctggagtagc aggtgtgagc caccgcgcct ggccaaaatc
     6061 tgcattcttt tttttttttt tttttttttt ttgagactgt ctcgctgtgt cacccaggcc
     6121 agagtgcagt agcacgatct cagctcacta caacctccac ctcctggatt caagcgattc
     6181 tcctgtctca gcctcccgag tagctgggac tacaggtgct tgccaccaca cccggctaat
     6241 tttttgtatt tttagtagag acggggtttc accgtgttag ccaggatggt ctcgatctcc
     6301 tgactttgcg atccccctgc ctcggcctcc caaagtgctg ggattacagg cgtgggccac
     6361 cgcgcttggc caaaatctgc attcttaatc acaaacttac gcattgaatg ttaaggctaa
     6421 aaggtcatct ggaaatgctt aattttaaaa tattttcaag cctcaccaca ttagagcaaa
     6481 tgttaatgta gagccctgta aaggtgggaa ggtggtgtct atgtgtgtgc ttgtgtatgt
     6541 gggggtatag accatatagt tgatataaca acagaatttg ggtgttacag acctttcagc
     6601 atggatggat tactaatttt caggtatcga aactgaaatt tgatacctga tcctgtggta
     6661 aagtatgtta aactatggtt ttggagtgat tattttgagg ttcattttca gcctcactga
     6721 acagtgtttt acgcacatgt gaaaagtatc cacatttgtt tccaactaaa atttgctttt
     6781 atttggtgag aaaagttgtg tgcgtgtgtt tgttgtaggg aataattagg gaattggaag
     6841 agaggccaaa aacaaacctg aattactttt gtttcttgtg tttgagccac gattctatcc
     6901 agatagcagt ttactctgag cagtaacaat gaacaagcag tatagcattt agcaaacctg
     6961 gaattgtttg tatatggttt tcattcttgg aagcataaag aaaaaatatg cattaaatga
     7021 attgtaaatt ttgacttgtt aaataacatg tttttcacta taactaatag gattttaata
     7081 tttaaagaat tttgttgctt ccatgacaaa atatcccatt ggactatttt ataacctcag
     7141 taatcaacat ttaagagtcc ttaattggag atctgttttc tctattacct accatcctgc
     7201 aatatgctga aatctttcta agttgcttat cttaattcta atggtgataa ttgaaaaaag
     7261 tgtgctggaa atacaggctc ttatctggtt gagtactggg ggtgggaagg atttagtaat
     7321 gtcataatct gttgaaggta atatctatag ataactaaga tagttccttt ttttttgtag
     7381 ttctgtgact cagacaaata agattttgag aattatgtag tttttaggtg tctgtaacat
     7441 ccactagtaa aacttggcaa atgaaagaaa attgtgaagt caccacttta actgagtcaa
     7501 aattttgttt gaataagctg atgaaaatag acatgtaccc tagaagtaga tactctaaaa
     7561 ttatacagac atgaatgtct tttttaaaag gttgtcatta ttgacctaat attgagtaat
     7621 ctttctgcgt tattccaaat tgaaatttgt ttgctcttca ttgtaacttt tatgtaaaag
     7681 tcctttaaaa ggggattcaa ttataaggct atttgactat agggcagatt tttataagta
     7741 aacattcccc caattccact tatgctaact gtctcatgac agtaaagttt actccttttt
     7801 agaaaccctt tctcagtatt ttaatttctg tcattgaatc atttaaataa taaccttttg
     7861 tttttatagc aaagaaatca tctgactttt ctgtgtgatg tttcttggca aaataagcac
     7921 ttgatgtatg gtcatgtaca taatggatat tcattaattt tgtgattagt gctgagtttt
     7981 ctaaactact atcttaagct cttaggcacc ctattatgga tctaattcaa accaatatgt
     8041 aggaaatgga gaaagtagga cttcagtttg cgcttcccaa taactttaaa tatatccacc
     8101 ttttccaagt gtttaagccc taaaacatct atctttattt ttttacctgg catttttgtt
     8161 agaaaataga ttacgtttta aagtaacatt aaaaaaattc ttcagtaaga taattgcttt
     8221 taataagtat atttttcttg ctcttggctc tatacatttt tgcataatat tttagtcttg
     8281 aaaagctttt cattttctta actctggaaa ataatagttt ggaactaaat tagtttgaga
     8341 aatctgaatc atctctcttt aaatctgttc agttagtctc atgtattctc aggggaaaat
     8401 gtctttattt tactaagcgg aagtagtagt catattgagg cagaaatttg tagcccaaac
     8461 aaggtaggtc ttcgctgaaa ctaatttgaa ctattcctat ttgaagcaaa ttgaacacta
     8521 ttataaatct agactggcta attagatgga aactttgatg gttaggttct ttaagaggca
     8581 tacaatccgt tatgagaatg tttatgttta tgttttaatt tttatcaaaa taacctcaga
     8641 ggaggtacat gtgagtaaac tgtcttaatg gttgattact tggaacccac ccattaattc
     8701 taaatgatgt aatggtctat aaggtagtaa tctggcacag cttcagtaat gtgtgctgtg
     8761 tttgtaaaaa ggtgaagtac tttattggca ttttctaagc cctctgacat tgttagtgtc
     8821 tgggttggtt ggtttgcatt ttactattat ggtggaatct gtgttccttc accattggtt
     8881 aagtctgagg aactaacagt gaaattcatt gatggccaac ttggataaaa atgaagaatg
     8941 atattttccc agtttactac acatggacca atagtgatta tttgggagag aacactgggt
     9001 agtattgttt gacttaagaa ccttaaatat attgaaaagt aatggcattc ttgctcatga
     9061 tttgcatttg ttagtgaggt ctcaccatag tattttaatg tagcttctta ttaaaatttt
     9121 attcataaat agtttagcag tcacagaggt gaaaaaaaaa agatttgcac catcatatcc
     9181 gagtctttac taataaaatg aggctgctta agtacccaag tggagcaagg gaagagttac
     9241 tacagttact gtaagtctga gttagaaaaa atacagagca tctagttatt gagcaaagcc
     9301 cccttttacc tgttcgctta ttcaaagaga aacaatagaa tttgcttctc agtacatgtt
     9361 tttaaaattg agaatctctg atgtgacaaa atcaattttt acaaaagttg aattaaaaac
     9421 ttttaaaaat tgcttgtctt tgggggtatg tctacatatt cgtttaaatt tagaaattcc
     9481 cacatgttta agatatatgc ccatcccctt tttagagtaa tcaaaatttc tatcacagtt
     9541 cacatactgg aatacatagt aaaattgaga tgtgtccaag agattttcaa tgttaattag
     9601 ctcattctaa atagccaata taaggtaact tctgtttaaa aaaaaaaaaa actagggaaa
     9661 agttttaaat gtattagtat caggctctga ggaaatttaa tgcacattga ctttttaaac
     9721 tatggattga actcctcagt ttaatacaat ttgtgttttt gttaactagc agcagaattt
     9781 cagcatttgc tacttactgg tagagaagaa aaatcccaca gccctgccag tacaggttag
     9841 tttaatctgt aagtacctga tgttcctatt tttttcaaac atatccatat aactcacaca
     9901 aggaagaaag ctgtgcggtt acttaaatgt tagtataact aataatagat ccattggaca
     9961 ctttaaacac tcagtacttg ggccaaagta gatctaggtt tgctaacccc agttgtaata
    10021 aaggtgtaat actgctcctt tgttatctcc ttgtggttca acctaagtag atacattgta
    10081 cataaaagga aaagacagtt tcagttggct atgcccttgt tgatagatga tatggagtcc
    10141 agggctttgg gtccagggtc ttttacttaa gctatttcat ggtggttctc tcattcacct
    10201 tttaactttt tacattatga atcaacctaa gaaaaaaggc aagtttcctc acatctagaa
    10261 atgataaatg gtgtacagtc ataagctaga atatgttttt ataatgcttt tttgttcttt
    10321 tagcaacact tgtaaataca agtactcctc tatttttgtt ctttttttgt aaactataac
    10381 gtatcccgtt ggtgtaccag tgagttcatt ttactgtaaa ctaagaataa catacctttt
    10441 taatactgaa agttgactac tcatcaagaa atgtagctag attctttatg taacactttt
    10501 gaggggcagt ggggacataa tgggttgtgg aaaatgtgtt ttaacatttt tatttttttt
    10561 ttattctacc cgagttcatt gttgtttgaa ccatcctcta aagatttcct ttaacctcta
    10621 aatgttgtgc ttttaggttg ataacaaatg taaagcactg aggagggagg aataaagcat
    10681 acaagttaat ttctaatttt cgcaagcctg aaccatccta atctgatagt aggatgtatg
    10741 gcttcttcct tttcaccttg tgtgatgttt aatttgagac gatctagcca taaaactagt
    10801 aatcttgaat tcctcttgag ctggatggtg attagccatt gtgaaaacag attatatgga
    10861 aattgtgcat attgctaaat tttaaaacat ggatttatca actgataata aaatatatct
    10921 tacaagataa ccacttgttt tttaatgtaa aattgcacaa gggcttaagt ttcattgcct
    10981 ttcacagttt aatctgtata tgaaatggtg tagatacagt ggaaatggtt ttccttaaaa
    11041 ccatctcttt aaagctgcct ttctggtgag tactgtttta tacttttata tattataatt
    11101 ttatcttcta aaattaactg aaataggaca ctttgattaa agaggtgagc actctgaatt
    11161 tctacatctt tggatattac ttgaatcaag aatattagaa aattatttta ccacctggca
    11221 tttccctttt aatttgctag ttcacttttt tctgaccttc acttaacaga ctataaatac
    11281 aaaaactttg aacacataaa ttatttcatt ttggtgagat ggaataaatg tttaaaatta
    11341 gtatttaaga aagttcttaa acattttttt tagttggcag ccaaaagatt tttcttagtg
    11401 ctttggagac attgcatagg tgtaaaatta agataccaga acttcattct gttcttgttg
    11461 aagctgttgt tgtggtgatt catgagcagt aagctggagt tagagtggaa gaagggttta
    11521 ccaaaattct tcctgcagac tagttgctta cagggtttct ttgagaggct taaaaatttc
    11581 aaaagtatta tttaagccac tctaaccctg catgaaaaat tggagttaga aatactgatt
    11641 tctgagacca cgtataccag tgaaaattag cttctgagta aatttctaat ttatgccctg
    11701 ctttatttag cctcgctata tgtaacacat ggattatttt ttccctctag tttttaacta
    11761 tatcctagat taaaaccagc atatgctaag aatgttttta cattctgttt cctcctgtga
    11821 tctttctgaa ccaataataa acagtcaact gtgatgcttt ttagtatgaa caatgatagt
    11881 tttctaaaat ctgaaaatca atacctgagt atgtgatgtg gcaatgcatt cttctagata
    11941 agcactaaac aaagtatgga ccctcaattt atgtctttaa gatttaaagt gaagtaaatt
    12001 tctaaggaac tgtgtccttt cctagcagga ataaacagtg aaaatttggt aagtatttaa
    12061 cttgaagtgc atgtaatagt gatgagagta agtagccaaa tttccgtaat ataaggtaat
    12121 gtttaaaagt gagcaataat tattgcatct cttttgcgac ttcatgtaga tgtgattaac
    12181 attttttaca aatttgcctg cataaagatt aaattggaac ataccttact cctttgtctg
    12241 gtttttttat tttgtatggt gctttaaata ctaattttat atttcaagct ttttgcaggg
    12301 tagaaataag tggctgttaa agaaaatatc ttcaagaagg attatttcag tgtccctttt
    12361 taaaactcga tgatggcttt cagtttattt aagtcttctg tttttcagct ccagttaaaa
    12421 ctgacaatag gcagctatca aaaatggaaa aaatcttgtg ctctttctgg aatattagag
    12481 gaatcagtta ataatagtaa agtggtatta acccaatact tgatttgcag tttttaaagc
    12541 agtttttaaa ttgagagaaa aggggctggg cccagctgag gcgggtggat ctcctgaggt
    12601 caggagtttg agaccagcct ggccaacata gtgaaacccc gtctctacta aaaatacaaa
    12661 aatcagccgg gtgtggtggg acgtgcctgt aaccccagct actctggagg ctgaggcagg
    12721 aaaatcgctt gaacccaggg ggaggaggtt gcagtgagcc gagatggcgc cgttgcactc
    12781 cagcttgggt gacagagcga gactccgtct caaaaaaaaa aagaaaaaaa gaaaaagtga
    12841 taagatttgg gagtctattc cctgggatgt tctattaata ataaagtgat aataaatgaa
    12901 ggttaaagtc aagtgttcaa ttactacacc aggaaagatt gattatttct gaggaaaagg
    12961 tccatttatt tccaaactag tctgtagtgg tttagagtaa gcattatttt atgaagtggt
    13021 acaagattgc aaaggttagt aaagggacct gtctgtcagg tcaatcttcg gtcttcactt
    13081 ttactggcaa gggattatgt gaagagtaag tcatacaagg gatatgattg taaggaggtc
    13141 ctgaacaaag catgataaat gttagtccat gtgtattatt aaatggtcta aagaaaaatc
    13201 atgactgatc gcataatttt taatgtaagt aaatgagctc actaagggta attaaatact
    13261 agcttttaaa atttaaagtt ctcacgaata ttagtgcatc ttgtcacttt gatttgtcac
    13321 ctggttaaat agctggaagc ttgtgcaaat gaaaaatgaa atggaagact acatttgtat
    13381 atatatctgt ataatttttg tttactagta ggttcagaga gagatctgag atgttcctta
    13441 acatgtagcc atgtaattag aactcacaag gggcattgaa atgtttttct ttttcagata
    13501 gtctggggct atttacttat tttaagtaag ccaagtctac catttgaaaa atggtgcttt
    13561 atttccatat ctgaagcctg aagttatttt ttagtttgtt ttcatctaaa agtggaaaga
    13621 tttttgcttc tgcgttatta agagcctctt tgtttggagg agatggttat ctccttcact
    13681 cattaacctt tgagtgcttg ttatctacaa agatgaataa aatctttcat ttattattta
//
