LOCUS       NM_003435               4924 bp    mRNA    linear   PRI 04-APR-2024
DEFINITION  Homo sapiens zinc finger protein 134 (ZNF134), mRNA.
ACCESSION   NM_003435 XM_005276674 XM_006726788 XM_011508876
VERSION     NM_003435.5
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 4924)
  AUTHORS   Luck,K., Kim,D.K., Lambourne,L., Spirohn,K., Begg,B.E., Bian,W.,
            Brignall,R., Cafarelli,T., Campos-Laborie,F.J., Charloteaux,B.,
            Choi,D., Cote,A.G., Daley,M., Deimling,S., Desbuleux,A., Dricot,A.,
            Gebbia,M., Hardy,M.F., Kishore,N., Knapp,J.J., Kovacs,I.A.,
            Lemmens,I., Mee,M.W., Mellor,J.C., Pollis,C., Pons,C.,
            Richardson,A.D., Schlabach,S., Teeking,B., Yadav,A., Babor,M.,
            Balcha,D., Basha,O., Bowman-Colin,C., Chin,S.F., Choi,S.G.,
            Colabella,C., Coppin,G., D'Amata,C., De Ridder,D., De Rouck,S.,
            Duran-Frigola,M., Ennajdaoui,H., Goebels,F., Goehring,L., Gopal,A.,
            Haddad,G., Hatchi,E., Helmy,M., Jacob,Y., Kassa,Y., Landini,S.,
            Li,R., van Lieshout,N., MacWilliams,A., Markey,D., Paulson,J.N.,
            Rangarajan,S., Rasla,J., Rayhan,A., Rolland,T., San-Miguel,A.,
            Shen,Y., Sheykhkarimli,D., Sheynkman,G.M., Simonovsky,E., Tasan,M.,
            Tejeda,A., Tropepe,V., Twizere,J.C., Wang,Y., Weatheritt,R.J.,
            Weile,J., Xia,Y., Yang,X., Yeger-Lotem,E., Zhong,Q., Aloy,P.,
            Bader,G.D., De Las Rivas,J., Gaudet,S., Hao,T., Rak,J.,
            Tavernier,J., Hill,D.E., Vidal,M., Roth,F.P. and Calderwood,M.A.
  TITLE     A reference map of the human binary protein interactome
  JOURNAL   Nature 580 (7803), 402-408 (2020)
   PUBMED   32296183
REFERENCE   2  (bases 1 to 4924)
  AUTHORS   Tommerup,N. and Vissing,H.
  TITLE     Isolation and fine mapping of 16 novel human zinc finger-encoding
            cDNAs identify putative candidate genes for developmental and
            malignant disorders
  JOURNAL   Genomics 27 (2), 259-264 (1995)
   PUBMED   7557990
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            DA098572.1, BC113410.1, BC042636.1 and AC003682.1.
            
            On Nov 23, 2018 this sequence version replaced NM_003435.4.
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR1803611.32972.1,
                                           SRR1803616.82301.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA1965299, SAMEA1966682
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000396161.10/ ENSP00000379464.4
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-220               DA098572.1         24-243
            221-2468            BC113410.1         1-2248
            2469-3192           BC042636.1         2451-3174
            3193-3196           AC003682.1         111705-111708
            3197-3556           BC042636.1         3175-3534
            3557-4924           AC003682.1         112069-113436
FEATURES             Location/Qualifiers
     source          1..4924
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="19"
                     /map="19q13.43"
     gene            1..4924
                     /gene="ZNF134"
                     /gene_synonym="pHZ-15"
                     /note="zinc finger protein 134"
                     /db_xref="GeneID:7693"
                     /db_xref="HGNC:HGNC:12918"
                     /db_xref="MIM:604076"
     exon            1..262
                     /gene="ZNF134"
                     /gene_synonym="pHZ-15"
                     /inference="alignment:Splign:2.1.0"
     exon            263..359
                     /gene="ZNF134"
                     /gene_synonym="pHZ-15"
                     /inference="alignment:Splign:2.1.0"
     CDS             320..1603
                     /gene="ZNF134"
                     /gene_synonym="pHZ-15"
                     /note="zinc finger protein 134 (clone pHZ-15)"
                     /codon_start=1
                     /product="zinc finger protein 134"
                     /protein_id="NP_003426.3"
                     /db_xref="CCDS:CCDS42638.1"
                     /db_xref="GeneID:7693"
                     /db_xref="HGNC:HGNC:12918"
                     /db_xref="MIM:604076"
                     /translation="MTLVTAGGAWTGPGCWHEVKDEESSSEQSISIAVSHVNTSKAGL
                     PAQTALPCDICGPILKDILHLDEHQGTHHGLKLHTCGACGRQFWFSANLHQYQKCYSI
                     EQPLRRDKSEASIVKNCTVSKEPHPSEKPFTCKEEQKNFQATLGGCQQKAIHSKRKTH
                     RSTESGDAFHGEQMHYKCSECGKAFSRKDTLVQHQRIHSGEKPYECSECGKAFSRKAT
                     LVQHQRIHTGERPYECSECGKTFSRKDNLTQHKRIHTGEMPYKCNECGKYFSHHSNLI
                     VHQRVHNGARPYKCSDCGKVFRHKSTLVQHESIHTGENPYDCSDCGKSFGHKYTLIKH
                     QRIHTESKPFECIECGKFFSRSSDYIAHQRVHTGERPFVCSKCGKDFIRTSHLVRHQR
                     VHTGERPYECSECGKAYSLSSHLNRHQKVHTAGRL"
     exon            360..4924
                     /gene="ZNF134"
                     /gene_synonym="pHZ-15"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2099..2104
                     /regulatory_class="polyA_signal_sequence"
                     /gene="ZNF134"
                     /gene_synonym="pHZ-15"
                     /note="hexamer: AATAAA"
     polyA_site      2125
                     /gene="ZNF134"
                     /gene_synonym="pHZ-15"
                     /note="major polyA site"
     regulatory      3538..3543
                     /regulatory_class="polyA_signal_sequence"
                     /gene="ZNF134"
                     /gene_synonym="pHZ-15"
                     /note="hexamer: ATTAAA"
     polyA_site      3556
                     /gene="ZNF134"
                     /gene_synonym="pHZ-15"
                     /note="major polyA site"
     regulatory      4899..4904
                     /regulatory_class="polyA_signal_sequence"
                     /gene="ZNF134"
                     /gene_synonym="pHZ-15"
                     /note="hexamer: AATAAA"
     polyA_site      4924
                     /gene="ZNF134"
                     /gene_synonym="pHZ-15"
                     /note="major polyA site"
ORIGIN      
        1 gcggtggaca tcttgtcggc tcttaggtgg aaccatcgga gcagaagctc ggggttgctg
       61 ggcggttccg aggtgacgga agcgggaggg tgcgggagaa gtcgctgttc gctctgcgga
      121 gtggctcgcc agcgaagacc ccgcctgcgc ccccggggac ggacgaccgc ggtgccaggg
      181 tcccgcgacc tgggaccccc tcgcggctcc gggtggtcta cgaactgtga tggcggcggc
      241 cgcggtgatg ggcccggcgc agatcctctg tggttgttga attgtaacaa gagagagaac
      301 tctggctgcc tgagagggca tgactctagt cacagcagga ggggcttgga caggccctgg
      361 ttgttggcat gaagtgaagg atgaagagtc atcttctgaa cagagcattt ctatagcagt
      421 gtcacatgtt aatacttcca aggcaggttt gcccgcacag acggctctcc cttgtgacat
      481 atgtggcccc atcttgaaag atattttgca cctggatgaa caccagggta cacaccatgg
      541 actgaaactt cacacatgtg gggcatgtgg gagacaattc tggttcagtg caaaccttca
      601 tcagtaccag aagtgttaca gtatagagca acccttaaga agggataaaa gtgaggcctc
      661 aattgtgaag aactgcacag ttagcaaaga acctcatccg tcagagaagc cctttacgtg
      721 taaggaggag cagaaaaact tccaggctac tttgggtggc tgccaacaaa aggccatcca
      781 cagtaagagg aagacacaca ggagcactga gagtggggat gcatttcatg gtgaacaaat
      841 gcattacaag tgcagtgaat gtgggaaagc tttcagccgc aaagacacac ttgtccagca
      901 ccagagaatt catagtggag agaagcctta tgagtgcagc gaatgtggga aagccttcag
      961 ccgcaaagct acacttgtcc agcatcagag aatccatact ggagaaaggc cttatgaatg
     1021 cagcgaatgt ggaaaaacct tcagtcgaaa agacaacctt actcagcaca agagaatcca
     1081 cactggagaa atgccttata agtgcaatga atgtgggaaa tattttagcc atcactccaa
     1141 tctaattgta caccagagag ttcacaatgg agcaaggcct tataagtgca gtgattgtgg
     1201 gaaagtcttc agacacaaat ctacacttgt tcagcatgag agtattcaca ctggagaaaa
     1261 tccttatgat tgcagtgatt gtgggaaatc ctttggccac aaatacaccc tcattaaaca
     1321 tcagcgaatt cacactgagt caaagccgtt tgagtgcatt gaatgcggga aattctttag
     1381 tcgaagttct gactatattg cacaccagag ggttcacact ggtgaaaggc cttttgtgtg
     1441 cagtaaatgt gggaaagact ttatcagaac ctcccacctt gttcgacacc aaagagttca
     1501 cactggagaa aggccatatg agtgcagtga atgtgggaag gcctacagct taagctccca
     1561 cctcaatcgg caccagaaag ttcacactgc aggcaggctt taggagtgct ttgaatacaa
     1621 caggactcat caatcagatg ttgaatttca tgtatctgaa cattgacaca aaggagatac
     1681 cttatggtgc caggtacgtg ggaaccttct agggatatgt tgcactttct gacttgctca
     1741 ggttttttgc cagagttatg tcactgtcaa tccatgtggc cgaaaccatc ttaactctac
     1801 cagctaagat accccagcat tggggaaggc agggttttgt attgtccagt ccctggagaa
     1861 aatcatgaaa tgcctgagtt cattgggggt cctcattccc ttctgtatga caggtatagg
     1921 tatggatatg acccattttt agccaagagg gtctgagctg tatctgctgg tggcttatac
     1981 aaaaagttta ctttcttcat ggatattctt ggtctcacat acttgtaatc aagtttttcc
     2041 agcctccaag tcacctggcc tgggaaagta cttgcctcat gttgctctgg tttgtgataa
     2101 taaaggcttt acagtttaag ccacatttaa tcttggggct tcttcttatg gtctggggtg
     2161 gattgaaaac aggctctgcc aaactgaaga cagcctttgt gcggtgcctc caactttgcc
     2221 tcaaatggga cagtgggttg agggagaaca gttcttagtc cagttttgat gttaacttcc
     2281 atagctgaca aagcttgtta agtaagaatt aagatcttgt gtagacctga tttgtctgga
     2341 ttttagagtt atttgagagc ccatatttca ccttgaggag ggtgctgctg ctgtgacagc
     2401 ctgcagtgtt ttgaaacagc atggattggg tgtcttgttt gcagcatgtg tcccatgttc
     2461 cccaacactg ttgagggaaa gctgttcctc aggacctgct gagtggccat attccctgaa
     2521 ggcctgaatc tgtttcacag gccactgttg gtaagatcta aagcatccag tagggaaaca
     2581 aaattgataa atattgagtg tgagtaattg ggattgggga gattgtggca aactagaggg
     2641 gaagtgccca ttgtaaaaac acatccacag acagtccagg cactaaggct gaatgggatc
     2701 agggtatcca gaaatctcag gatctccagg gccatgttac tgttaggtca aggtcactgg
     2761 tgcagcaacg aatgtagttt ttctagattc ctctccctcc ctgggctctt tacctaatgt
     2821 ctttgcggca caggcggtaa ccctgggagt aaagaggtgt ggtccaagga agtagctttt
     2881 gtgaccagct ggagtttctg gtgactcttt tggcaatggt cctcattgtt tgccagtttt
     2941 tcttactact gaggaagaga ttgtcttccc aagatatttg gagtgataag agtcaccata
     3001 gtgaggtaga gtcactctta gtgatgtcca gttgtccagt ttccaataga agtgggagat
     3061 ccagattttt aaatgggata actttttata ggttcactga ggtgtaatca acatgcaata
     3121 tattgcacat atttaaagtg tacgagttaa gtcttgatac acacacacac acacacacac
     3181 acacacacac acacacttga aactatcacc ctatcagtgg tattggacat atctgttacc
     3241 cccaaagtta acctgaggcc cttaaccttt ctctcagtgc tcgccttccc ccagaatccc
     3301 taggcaacca ctgagtagtt ttcactgtag gtaaatttgt cttttctaga attttatgta
     3361 agtctgccta taaagtgtta attttgcatg ctgtctttca tgcaacataa tttgaaattt
     3421 gtccatggta tgtatgaaca gtccatttta aaattactga gtcatattct gtatggatat
     3481 accacagttt atccatttat cttaattgat gtctgtactc cacccccatt tttaaatatt
     3541 aaaaagctgc tgcaaatatt gatgcatgag tctttatgtg gacacttagc tgagaacatt
     3601 tttaagcaga ggttttgaag gtgtgaccat atatcttact aattatagta aaatatattg
     3661 gaaaagagat acatacaggg aagaactgtg aaacagaaaa gacctaagat ttgatgattt
     3721 gggaaattct cagcccatct taattggaaa aaaaaaacaa accattgaaa ttaagagatt
     3781 cattgttagg aaagatagat gttttagaga gagagatgtt ttagagagat agccaaggat
     3841 gtttgctgat accgggatca aaacatacat cagaacactg tcacacaaaa agctctttga
     3901 agagattaaa tgtgacttgt agatcccctc aatacaaaca atttataaga agtttaaact
     3961 atcactcatc tcagcaaaag ccaaaaatat agatagggga ttccctagga ggaataatct
     4021 gcataaacct cttttctaat gttgtgaatt tcagtgatgt acaggagact cacaaaattc
     4081 ttgaaaattt tataccagtg gaaatgctca ccttgggtct aaagggacct tgaaagtatg
     4141 aagttaaagg gtgtaggcat gtaaagtgtg aagttaaagg ttgtaatatt ctatacatgg
     4201 gactggctgc ggaaacaggt gcaagccctt gctacctttc atgagaaagg aaggatgact
     4261 cagagcagag gagagtccag tgggcagagt cctgaaccat gtgatattcc catgtcttga
     4321 ctcccagtgg catttgccaa actagatttc agattttctt gggattggtg gttccatttt
     4381 ttttgttttc cccccttcca tttcctcccc ttttgaaaca atgcatatac atataactat
     4441 tatcctaggt ctttcccaac cttttgtttg ggagcagata actagttttc tagttttaca
     4501 gatccaaatg agacaggaat agcactgggt ggtcacagga ggatggaaaa tctcaacacc
     4561 ctggttttgg tgcagctgaa aaaaaaaaag aaaaacccaa acaacagcta aaacgggaac
     4621 taggcaaaga aaccgtggga taacagaaaa cccaaaacaa aagagaaaac tgccagaacc
     4681 ccagtcaggg tgacatgtct gtaactcttc caggcaaacc caaataaggg aggaggggtg
     4741 gtaatcaggg gtccctgaaa tcccctcttt tcccagaata cctaatgatt acccctatta
     4801 aaggaacacc catacaatta gaaacccaaa ctttgttttg catgacttgc tctcaggggc
     4861 actcccacac ttctctcttg tgtgtacttt tgcttcacaa taaaagctgc ttgcctttgc
     4921 ttca
//
