LOCUS       NM_033204               4642 bp    mRNA    linear   PRI 05-APR-2024
DEFINITION  Homo sapiens zinc finger protein 101 (ZNF101), transcript variant
            1, mRNA.
ACCESSION   NM_033204
VERSION     NM_033204.4
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 4642)
  AUTHORS   Luck,K., Kim,D.K., Lambourne,L., Spirohn,K., Begg,B.E., Bian,W.,
            Brignall,R., Cafarelli,T., Campos-Laborie,F.J., Charloteaux,B.,
            Choi,D., Cote,A.G., Daley,M., Deimling,S., Desbuleux,A., Dricot,A.,
            Gebbia,M., Hardy,M.F., Kishore,N., Knapp,J.J., Kovacs,I.A.,
            Lemmens,I., Mee,M.W., Mellor,J.C., Pollis,C., Pons,C.,
            Richardson,A.D., Schlabach,S., Teeking,B., Yadav,A., Babor,M.,
            Balcha,D., Basha,O., Bowman-Colin,C., Chin,S.F., Choi,S.G.,
            Colabella,C., Coppin,G., D'Amata,C., De Ridder,D., De Rouck,S.,
            Duran-Frigola,M., Ennajdaoui,H., Goebels,F., Goehring,L., Gopal,A.,
            Haddad,G., Hatchi,E., Helmy,M., Jacob,Y., Kassa,Y., Landini,S.,
            Li,R., van Lieshout,N., MacWilliams,A., Markey,D., Paulson,J.N.,
            Rangarajan,S., Rasla,J., Rayhan,A., Rolland,T., San-Miguel,A.,
            Shen,Y., Sheykhkarimli,D., Sheynkman,G.M., Simonovsky,E., Tasan,M.,
            Tejeda,A., Tropepe,V., Twizere,J.C., Wang,Y., Weatheritt,R.J.,
            Weile,J., Xia,Y., Yang,X., Yeger-Lotem,E., Zhong,Q., Aloy,P.,
            Bader,G.D., De Las Rivas,J., Gaudet,S., Hao,T., Rak,J.,
            Tavernier,J., Hill,D.E., Vidal,M., Roth,F.P. and Calderwood,M.A.
  TITLE     A reference map of the human binary protein interactome
  JOURNAL   Nature 580 (7803), 402-408 (2020)
   PUBMED   32296183
REFERENCE   2  (bases 1 to 4642)
  AUTHORS   Cornelis,M.C., Fornage,M., Foy,M., Xun,P., Gladyshev,V.N.,
            Morris,S., Chasman,D.I., Hu,F.B., Rimm,E.B., Kraft,P., Jordan,J.M.,
            Mozaffarian,D. and He,K.
  TITLE     Genome-wide association study of selenium concentrations
  JOURNAL   Hum Mol Genet 24 (5), 1469-1477 (2015)
   PUBMED   25343990
REFERENCE   3  (bases 1 to 4642)
  AUTHORS   Demirkan,A., van Duijn,C.M., Ugocsai,P., Isaacs,A.,
            Pramstaller,P.P., Liebisch,G., Wilson,J.F., Johansson,A., Rudan,I.,
            Aulchenko,Y.S., Kirichenko,A.V., Janssens,A.C., Jansen,R.C.,
            Gnewuch,C., Domingues,F.S., Pattaro,C., Wild,S.H., Jonasson,I.,
            Polasek,O., Zorkoltseva,I.V., Hofman,A., Karssen,L.C.,
            Struchalin,M., Floyd,J., Igl,W., Biloglav,Z., Broer,L., Pfeufer,A.,
            Pichler,I., Campbell,S., Zaboli,G., Kolcic,I., Rivadeneira,F.,
            Huffman,J., Hastie,N.D., Uitterlinden,A., Franke,L., Franklin,C.S.,
            Vitart,V., Nelson,C.P., Preuss,M., Bis,J.C., O'Donnell,C.J.,
            Franceschini,N., Witteman,J.C., Axenovich,T., Oostra,B.A.,
            Meitinger,T., Hicks,A.A., Hayward,C., Wright,A.F., Gyllensten,U.,
            Campbell,H. and Schmitz,G.
  CONSRTM   DIAGRAM Consortium; CARDIoGRAM Consortium; CHARGE Consortium;
            EUROSPAN consortium
  TITLE     Genome-wide association study identifies novel loci associated with
            circulating phospho- and sphingolipid concentrations
  JOURNAL   PLoS Genet 8 (2), e1002490 (2012)
   PUBMED   22359512
REFERENCE   4  (bases 1 to 4642)
  AUTHORS   Waterworth,D.M., Ricketts,S.L., Song,K., Chen,L., Zhao,J.H.,
            Ripatti,S., Aulchenko,Y.S., Zhang,W., Yuan,X., Lim,N., Luan,J.,
            Ashford,S., Wheeler,E., Young,E.H., Hadley,D., Thompson,J.R.,
            Braund,P.S., Johnson,T., Struchalin,M., Surakka,I., Luben,R.,
            Khaw,K.T., Rodwell,S.A., Loos,R.J., Boekholdt,S.M., Inouye,M.,
            Deloukas,P., Elliott,P., Schlessinger,D., Sanna,S., Scuteri,A.,
            Jackson,A., Mohlke,K.L., Tuomilehto,J., Roberts,R., Stewart,A.,
            Kesaniemi,Y.A., Mahley,R.W., Grundy,S.M., McArdle,W., Cardon,L.,
            Waeber,G., Vollenweider,P., Chambers,J.C., Boehnke,M.,
            Abecasis,G.R., Salomaa,V., Jarvelin,M.R., Ruokonen,A., Barroso,I.,
            Epstein,S.E., Hakonarson,H.H., Rader,D.J., Reilly,M.P.,
            Witteman,J.C., Hall,A.S., Samani,N.J., Strachan,D.P., Barter,P.,
            van Duijn,C.M., Kooner,J.S., Peltonen,L., Wareham,N.J.,
            McPherson,R., Mooser,V. and Sandhu,M.S.
  CONSRTM   Wellcome Trust Case Control Consortium
  TITLE     Genetic variants influencing circulating lipid levels and risk of
            coronary artery disease
  JOURNAL   Arterioscler Thromb Vasc Biol 30 (11), 2264-2276 (2010)
   PUBMED   20864672
REFERENCE   5  (bases 1 to 4642)
  AUTHORS   Aulchenko,Y.S., Ripatti,S., Lindqvist,I., Boomsma,D., Heid,I.M.,
            Pramstaller,P.P., Penninx,B.W., Janssens,A.C., Wilson,J.F.,
            Spector,T., Martin,N.G., Pedersen,N.L., Kyvik,K.O., Kaprio,J.,
            Hofman,A., Freimer,N.B., Jarvelin,M.R., Gyllensten,U., Campbell,H.,
            Rudan,I., Johansson,A., Marroni,F., Hayward,C., Vitart,V.,
            Jonasson,I., Pattaro,C., Wright,A., Hastie,N., Pichler,I.,
            Hicks,A.A., Falchi,M., Willemsen,G., Hottenga,J.J., de Geus,E.J.,
            Montgomery,G.W., Whitfield,J., Magnusson,P., Saharinen,J.,
            Perola,M., Silander,K., Isaacs,A., Sijbrands,E.J.,
            Uitterlinden,A.G., Witteman,J.C., Oostra,B.A., Elliott,P.,
            Ruokonen,A., Sabatti,C., Gieger,C., Meitinger,T., Kronenberg,F.,
            Doring,A., Wichmann,H.E., Smit,J.H., McCarthy,M.I., van Duijn,C.M.
            and Peltonen,L.
  CONSRTM   ENGAGE Consortium
  TITLE     Loci influencing lipid levels and coronary heart disease risk in 16
            European population cohorts
  JOURNAL   Nat Genet 41 (1), 47-55 (2009)
   PUBMED   19060911
REFERENCE   6  (bases 1 to 4642)
  AUTHORS   Looman,C., Hellman,L. and Abrink,M.
  TITLE     A novel Kruppel-Associated Box identified in a panel of mammalian
            zinc finger proteins
  JOURNAL   Mamm Genome 15 (1), 35-40 (2004)
   PUBMED   14727140
REFERENCE   7  (bases 1 to 4642)
  AUTHORS   Bellefroid,E.J., Marine,J.C., Ried,T., Lecocq,P.J., Riviere,M.,
            Amemiya,C., Poncelet,D.A., Coulie,P.G., de Jong,P., Szpirer,C. et
            al.
  TITLE     Clustered organization of homologous KRAB zinc-finger genes with
            enhanced expression in human T lymphoid cells
  JOURNAL   EMBO J 12 (4), 1363-1374 (1993)
   PUBMED   8467795
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            CR999939.1, AY149174.1, AC011458.7 and BM972114.1.
            
            On Nov 23, 2018 this sequence version replaced NM_033204.3.
            
            Summary: Zinc finger proteins (ZNFs), such as ZNF101, bind nucleic
            acids and perform many key functions, the most important of which
            is regulating transcription (summary by Bellefroid et al., 1993
            [PubMed 8467795]). See ZNF91 (MIM 603971) for general information
            on ZNFs.[supplied by OMIM, Nov 2010].
            
            Transcript Variant: This variant (1) represents the longer
            transcript and encodes the longer isoform (1).
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: DB138422.1, SRR1803614.63819.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA1965299, SAMEA1966682
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000592502.2/ ENSP00000468049.1
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-15                CR999939.1         52-66
            16-1465             AY149174.1         1-1450
            1466-4610           AC011458.7         59685-62829
            4611-4642           BM972114.1         17-48               c
FEATURES             Location/Qualifiers
     source          1..4642
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="19"
                     /map="19p13.11"
     gene            1..4642
                     /gene="ZNF101"
                     /gene_synonym="HZF12"
                     /note="zinc finger protein 101"
                     /db_xref="GeneID:94039"
                     /db_xref="HGNC:HGNC:12881"
                     /db_xref="MIM:603983"
     exon            1..128
                     /gene="ZNF101"
                     /gene_synonym="HZF12"
                     /inference="alignment:Splign:2.1.0"
     CDS             126..1436
                     /gene="ZNF101"
                     /gene_synonym="HZF12"
                     /note="isoform 1 is encoded by transcript variant 1; zinc
                     finger protein 101 (Y2); zinc finger protein 12; zinc
                     finger protein HZF12"
                     /codon_start=1
                     /product="zinc finger protein 101 isoform 1"
                     /protein_id="NP_149981.2"
                     /db_xref="CCDS:CCDS32971.1"
                     /db_xref="GeneID:94039"
                     /db_xref="HGNC:HGNC:12881"
                     /db_xref="MIM:603983"
                     /translation="MDSVAFEDVAVNFTQEEWALLSPSQKNLYRDVTLETFRNLASVG
                     IQWKDQDIENLYQNLGIKLRSLVERLCGRKEGNEHRETFSQIPDCHLNKKSQTGVKPC
                     KCSVCGKVFLRHSFLDRHMRAHAGHKRSECGGEWRETPRKQKQHGKASISPSSGARRT
                     VTPTRKRPYECKVCGKAFNSPNLFQIHQRTHTGKRSYKCREIVRAFTVSSFFRKHGKM
                     HTGEKRYECKYCGKPIDYPSLFQIHVRTHTGEKPYKCKQCGKAFISAGYLRTHEIRSH
                     ALEKSHQCQECGKKLSCSSSLHRHERTHSGGKLYECQKCAKVFRCPTSLQAHERAHTG
                     ERPYECNKCGKTFNYPSCFRRHKKTHSGEKPYECTRCGKAFGWCSSLRRHEMTHTGEK
                     PFDCKQCGKVFTFSNYLRLHERTHLAGRSQCFGRRQGDHLSPGV"
     exon            129..255
                     /gene="ZNF101"
                     /gene_synonym="HZF12"
                     /inference="alignment:Splign:2.1.0"
     exon            256..316
                     /gene="ZNF101"
                     /gene_synonym="HZF12"
                     /inference="alignment:Splign:2.1.0"
     exon            317..4642
                     /gene="ZNF101"
                     /gene_synonym="HZF12"
                     /inference="alignment:Splign:2.1.0"
     regulatory      4618..4623
                     /regulatory_class="polyA_signal_sequence"
                     /gene="ZNF101"
                     /gene_synonym="HZF12"
                     /note="hexamer: AATAAA"
     polyA_site      4642
                     /gene="ZNF101"
                     /gene_synonym="HZF12"
                     /note="major polyA site"
ORIGIN      
        1 attcgggtcc gggttttagt tcctcgggga gcccctggtg ccccggatac ggctgatttt
       61 gtcgtgtggg acctgttctg gctgctccag ccccaggaag gacccaggac acccggaagc
      121 cggaaatgga ctcagtggcc tttgaggatg tggctgtgaa cttcacccag gaggagtggg
      181 ctttgctgag tccttcccag aagaatctct acagagatgt gacgctggaa accttcagga
      241 acctggcctc ggtcggaatc caatggaaag accaggacat tgagaatctg taccaaaacc
      301 tggggattaa gctaagaagt ctggtggaga gactctgtgg acgtaaagaa gggaatgaac
      361 acagagaaac tttcagccag attcctgatt gtcacctgaa caagaaaagt caaactggag
      421 tgaaaccatg caaatgcagc gtgtgtggga aagtcttcct ccgtcattca ttcctggaca
      481 ggcacatgag agctcatgct ggacacaaac gatctgagtg tggtggggaa tggagagaga
      541 cgccccgtaa acagaaacaa catgggaaag cctccatttc ccccagtagt ggtgcacggc
      601 gcacagtaac accaactcga aagagacctt atgaatgcaa ggtgtgcggg aaagccttta
      661 attctcccaa tttatttcaa atccatcaaa gaactcacac tggaaagagg tcctataaat
      721 gtagggaaat agtgagagcc ttcacagttt ccagtttctt tcgaaaacat ggaaaaatgc
      781 atactggaga aaaacgctat gaatgtaaat actgtggaaa acctatcgat tatcccagtt
      841 tatttcaaat tcatgttaga actcacactg gagaaaaacc ttacaaatgt aaacaatgtg
      901 gtaaagcctt catttccgca ggttaccttc ggacacatga aatcagatct cacgcgctgg
      961 agaaatccca ccaatgtcag gaatgtggga aaaaactcag ttgttccagt tcccttcaca
     1021 gacatgaaag aactcatagt ggaggaaaac tctacgaatg tcaaaaatgt gccaaagtct
     1081 ttagatgtcc cacgtccctt caagcacatg aaagagctca cactggagaa agaccttatg
     1141 aatgtaataa atgtggtaaa accttcaatt atcccagttg ttttcgaaga cataaaaaaa
     1201 ctcatagtgg agaaaagcca tatgaatgta caaggtgtgg taaagccttt gggtggtgca
     1261 gttccctccg aagacatgaa atgactcaca ctggagaaaa accctttgat tgtaaacagt
     1321 gtggtaaagt ctttactttt tcaaattacc ttagacttca tgaaagaact catttggccg
     1381 ggcgtagcca gtgctttggc aggaggcagg gggatcacct gagcccagga gtttgagacc
     1441 agcctgggca acataagaag gccccatatc ggctgggtac ggtggctcac gcttgtaatc
     1501 ccagcacttt gggaggctga ggcgggtgga tcacctgagg tcaggagttc aagactagcc
     1561 tggccaacat ggtgaaaccc cgtctctact aaaaatacaa aaaaattaac tgggcatggt
     1621 ggtgggcacc tgtaatctca gctactcggg aggccgaggc aggagaatcg cttgaacctg
     1681 ggaggtggag gttgcagtga gccgagatca cgccattgca ctccagcctg ggcgacaaaa
     1741 gtgagactcc atcacacaca cacacaaaaa agccccatat cacgtggtgg ctcatgcctg
     1801 taaaaccagc actttgggaa gccgaggtgg gtggatcacg aggtccagag atggagacta
     1861 tcttggccaa catggtgaaa ccccgtctct actaaaaata caaaaattag ccaggcgtgg
     1921 tggtgtgtgc ctgtagtccc agctactcgg gaggctgagg caggagaatt gcttgaacca
     1981 gggacttgga ggttgcagtg agccgagatc gcgccgctgc actccagcct ggtgacagag
     2041 cgagacttcg tctcaaaaca aacaaaaaaa agaaggcccc atatctccaa agaaaaaaaa
     2101 aattaactgg gtgaggtggt gcatccctgt agttctagct gctcagaaag ctgaggtggg
     2161 aggaaccctt gagcctggga ggttgaggct gcagtgagct gagatcgtgc cactacactc
     2221 cagcctggat gacggtgaca ctctgtctca gaaaaaaagg gaaagaaata attctcattt
     2281 atacaggaga gaaatcctat gaatgtaagg aatatgggaa tacattcagt ttccaaagat
     2341 atgaaaagac taactggaaa aaaatccaaa gacctcagat attccagttc tattcagagc
     2401 cataaaagga ctcatactgg agaaaaattg tagaaatgta cagaatatgg ggaaactctc
     2461 attgctctca tctccattca aagacacgtg tcagtgcaca ctggagatgg atggtatgaa
     2521 tcgaagaata cacactggat ggaaacgtta gtagtttgga aaatacagga aacttccatt
     2581 ttaacaataa ttaaaattca catgggctgt gcacagtggc tctcccctgt aatcccagca
     2641 ttttgggagg ctggggtggg tagattgctt gaggccaggt attcaagacc agcctggcaa
     2701 cctggagaaa tcccatgtat acaaaaaata gaaaagttag ccagggatga tggtgttcgc
     2761 ctgtagtccc agctactcag gaagctgagg tgggaggatt gcttgagttt gggaggtcga
     2821 ggttgcagtg agtggagatt gcgccactgg actccagcct gggcaacagt gagaccctgt
     2881 ctaaaaaaat taatcatgtg agaacatcca ctcgaaagaa atcctataaa cgtaagtaat
     2941 tttgaaagcc tgatgcaaat taattattat ataatgctca aaaacttaat catgaatgag
     3001 ttattacaca aagttataaa tatatagcat ttatcagtgg ctcattcttt tttctttctt
     3061 tttttttttt ttttttgaga tggagttttg ccctgtcgcc caggctggag tgcagtggca
     3121 caatctcggc tcactgcaac ctccgcctcc tgggtgtgag caattttcct gcctcagcct
     3181 cctgagtaac tgggattata agcacatgcc accacgcctg gctaattttt ttgtattttt
     3241 agtagagacg gggcttcacc atgtggttca ggctggtctc agactcctga ccttgtgatc
     3301 cgccctcctt ggcctcccaa agtgctgaga ttacaggtgt gagccaccgc gcctggcctt
     3361 tttttttttt cccgagacac agtctcactc tgttgcccag gctagagtgc agtggcgcga
     3421 tcttgactca ctgtaacctc tgacttctgg gttcaagcaa ttctcctgct tcagtctccg
     3481 aagcatctgg gattacaggc gcacgccacc atgcccagct aaatttttgg tatttttgta
     3541 gaaacagggt ttttccacat tggccaggct ggtcttgaac tcctgacctc aaggaatcca
     3601 tcctcttcag cctcgcaaag tgctgagatt ataggcatga gacaccttgc ccggcccctg
     3661 tgactcattc ttaaaaagga tctttggatt atgggtttcc acttttgcaa ggaaatgtga
     3721 gaatgatact ctttaagcag tggtacctga ggtttaatag gaagtgtttt tatcctaagt
     3781 tagttaataa aatttttttc tatccatttt ggttttcatt tttttctatc cattttaaag
     3841 tgttggatct gtgggtgaag tgaaatttat ttctaatatg taagcaggtt taatttttat
     3901 gtagtgttta attgttctgt gatgaatggg ccattacaaa atgagtctat ttttgtttgt
     3961 tttcttttgt ttttgagact gagtcttgct ctgtcgccag gctgaagtgt agtggcgcga
     4021 tcttggctca ctgcaacctc cacctcccgg gttcaagtaa tccccctgcc ttagcctcct
     4081 acaggcgcgt gccgacatgc ctggctaatt ttttgtattt tagtagagac ggggtttcat
     4141 tgtactggcc aggatggtct tgatttcctg accttgtgat ccaccccacc ttggcctccc
     4201 aaagtgctga gattacagga gtgagccact gcgaccggcc catgagtctt tattaataga
     4261 gatttcttac tggtgttatg tggcagattc tgcatattcc tcacccatca tatgtattcc
     4321 actttccttt attatgggga aaactactct ttttggcatg atacaatgtt gactccattt
     4381 tctttgctaa taaggacttg gtatcaattt atcagtatgt aaagtttacc atagagtatt
     4441 gtctcatgtg aatcattccc attttttgct ctttactctt tgtcgttatt tctgagtatt
     4501 atttggatgg ttcattttga cttaaggata gccctgtgat atgacaatat ttttatctaa
     4561 tctgatggag aaagcattta gtctcctgat caagtatgat gttagctgca ggtttttaat
     4621 aaatgcctta attcagtttg aa
//
