LOCUS       NM_001281781            4843 bp    mRNA    linear   PRI 24-OCT-2024
DEFINITION  Homo sapiens zinc finger MYND-type containing 8 (ZMYND8),
            transcript variant 15, mRNA.
ACCESSION   NM_001281781 XM_005260376
VERSION     NM_001281781.3
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 4843)
  AUTHORS   Tang,K., Yin,T., Deng,B., Wang,M., Ren,Z., Wang,S., Liu,X., Li,H.,
            Wang,J., Du,Y., Zhou,J., Chen,Y. and Wang,Y.
  TITLE     USP7 deubiquitinates epigenetic reader ZMYND8 to promote breast
            cancer cell migration and invasion
  JOURNAL   J Biol Chem 300 (9), 107672 (2024)
   PUBMED   39128723
  REMARK    GeneRIF: USP7 deubiquitinates epigenetic reader ZMYND8 to promote
            breast cancer cell migration and invasion.
REFERENCE   2  (bases 1 to 4843)
  AUTHORS   Guha,D., Singh,V., Nandi,S., Ramos,E.I., Gadad,S.S. and Das,C.
  TITLE     ZMYND8 Is a Regulator of Sonic Hedgehog Signaling in ATRA-Mediated
            Differentiation of Neuroblastoma Cells
  JOURNAL   Biochemistry 63 (12), 1534-1542 (2024)
   PUBMED   38804064
  REMARK    GeneRIF: ZMYND8 Is a Regulator of Sonic Hedgehog Signaling in
            ATRA-Mediated Differentiation of Neuroblastoma Cells.
REFERENCE   3  (bases 1 to 4843)
  AUTHORS   Pintacuda,G., Hsu,Y.H., Tsafou,K., Li,K.W., Martin,J.M.,
            Riseman,J., Biagini,J.C., Ching,J.K.T., Mena,D.,
            Gonzalez-Lozano,M.A., Egri,S.B., Jaffe,J., Smit,A.B., Fornelos,N.,
            Eggan,K.C. and Lage,K.
  TITLE     Protein interaction studies in human induced neurons indicate
            convergent biology underlying autism spectrum disorders
  JOURNAL   Cell Genom 3 (3), 100250 (2023)
   PUBMED   36950384
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 4843)
  AUTHORS   Adhikary,S., Singh,V., Choudhari,R., Yang,B., Adhikari,S.,
            Ramos,E.I., Chaudhuri,S., Roy,S., Gadad,S.S. and Das,C.
  TITLE     ZMYND8 suppresses MAPT213 LncRNA transcription to promote neuronal
            differentiation
  JOURNAL   Cell Death Dis 13 (9), 766 (2022)
   PUBMED   36064715
  REMARK    Publication Status: Online-Only
REFERENCE   5  (bases 1 to 4843)
  AUTHORS   Dias,K.R., Carlston,C.M., Blok,L.E.R., De Hayr,L., Nawaz,U.,
            Evans,C.A., Bayrak-Toydemir,P., Htun,S., Zhu,Y., Ma,A., Lynch,S.A.,
            Moorwood,C., Stals,K., Ellard,S., Bainbridge,M.N., Friedman,J.,
            Pappas,J.G., Rabin,R., Nowak,C.B., Douglas,J., Wilson,T.E., Guillen
            Sacoto,M.J., Mullegama,S.V., Palculict,T.B., Kirk,E.P.,
            Pinner,J.R., Edwards,M., Montanari,F., Graziano,C., Pippucci,T.,
            Dingmann,B., Glass,I., Mefford,H.C., Shimoji,T., Suzuki,T.,
            Yamakawa,K., Streff,H., Schaaf,C.P., Slavotinek,A.M., Voineagu,I.,
            Carey,J.C., Buckley,M.F., Schenck,A., Harvey,R.J. and Roscioli,T.
  TITLE     De Novo ZMYND8 variants result in an autosomal dominant
            neurodevelopmental disorder with cardiac malformations
  JOURNAL   Genet Med 24 (9), 1952-1966 (2022)
   PUBMED   35916866
  REMARK    GeneRIF: De Novo ZMYND8 variants result in an autosomal dominant
            neurodevelopmental disorder with cardiac malformations.
REFERENCE   6  (bases 1 to 4843)
  AUTHORS   Nelson,D., Yoshida,E.M., Paulson,M.S., Hengen,P.N., Ge,D.,
            Kanwar,B., McNally,J., Pang,P.S., Subramanian,G.M.,
            McHutchison,J.G., Urbanek,P., Lawitz,E. and Urban,T.J.
  TITLE     Genome-wide association study to characterize serum bilirubin
            elevations in patients with HCV treated with GS-9256, an HCV NS3
            serine protease inhibitor
  JOURNAL   Antivir Ther 19 (7), 679-686 (2014)
   PUBMED   24503447
REFERENCE   7  (bases 1 to 4843)
  AUTHORS   Miles,R.R., Crockett,D.K., Lim,M.S. and Elenitoba-Johnson,K.S.
  TITLE     Analysis of BCL6-interacting proteins by tandem mass spectrometry
  JOURNAL   Mol Cell Proteomics 4 (12), 1898-1909 (2005)
   PUBMED   16147992
REFERENCE   8  (bases 1 to 4843)
  AUTHORS   Westendorf,J.J. and Koka,S.
  TITLE     Identification of FHOD1-binding proteins and mechanisms of
            FHOD1-regulated actin dynamics
  JOURNAL   J Cell Biochem 92 (1), 29-41 (2004)
   PUBMED   15095401
REFERENCE   9  (bases 1 to 4843)
  AUTHORS   Eichmuller,S., Usener,D., Dummer,R., Stein,A., Thiel,D. and
            Schadendorf,D.
  TITLE     Serological detection of cutaneous T-cell lymphoma-associated
            antigens
  JOURNAL   Proc Natl Acad Sci U S A 98 (2), 629-634 (2001)
   PUBMED   11149944
REFERENCE   10 (bases 1 to 4843)
  AUTHORS   Fossey,S.C., Kuroda,S., Price,J.A., Pendleton,J.K., Freedman,B.I.
            and Bowden,D.W.
  TITLE     Identification and characterization of PRKCBP1, a candidate
            RACK-like protein
  JOURNAL   Mamm Genome 11 (10), 919-925 (2000)
   PUBMED   11003709
COMMENT     REVIEWED REFSEQ: This record has been curated by NCBI staff. The
            reference sequence was derived from DC362133.1, DQ368677.1,
            AL022342.7, DR422399.1, BC146802.1 and AI275390.1.
            
            On Jun 2, 2019 this sequence version replaced NM_001281781.2.
            
            Summary: The protein encoded by this gene is a receptor for
            activated C-kinase (RACK) protein. The encoded protein has been
            shown to bind in vitro to activated protein kinase C beta I. In
            addition, this protein is a cutaneous T-cell lymphoma-associated
            antigen. Finally, the protein contains a bromodomain and two zinc
            fingers, and is thought to be a transcriptional regulator. Multiple
            transcript variants encoding several different isoforms have been
            found for this gene. [provided by RefSeq, Jul 2008].
            
            Transcript Variant: This variant (15) has multiple differences in
            the coding region but maintains the reading frame, compared to
            variant 1. The encoded isoform (o) is shorter, compared to isoform
            a.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: DQ368677.1, SRR7346977.1632828.1
                                           [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA1965299,
                                           SAMEA1966682 [ECO:0006172]
            ##Evidence-Data-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-29                DC362133.1         346-374
            30-2863             DQ368677.1         1-2834
            2864-2864           AL022342.7         99092-99092         c
            2865-3296           DQ368677.1         2836-3267
            3297-3783           DR422399.1         206-692
            3784-4600           BC146802.1         2811-3627
            4601-4843           AI275390.1         1-243               c
FEATURES             Location/Qualifiers
     source          1..4843
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="20"
                     /map="20q13.12"
     gene            1..4843
                     /gene="ZMYND8"
                     /gene_synonym="PRKCBP1; PRO2893; RACK7"
                     /note="zinc finger MYND-type containing 8"
                     /db_xref="GeneID:23613"
                     /db_xref="HGNC:HGNC:9397"
                     /db_xref="MIM:615713"
     exon            1..43
                     /gene="ZMYND8"
                     /gene_synonym="PRKCBP1; PRO2893; RACK7"
                     /inference="alignment:Splign:2.1.0"
     CDS             30..3296
                     /gene="ZMYND8"
                     /gene_synonym="PRKCBP1; PRO2893; RACK7"
                     /note="isoform o is encoded by transcript variant 15; CTCL
                     tumor antigen se14-3; RACK like clone 7; protein kinase
                     C-binding protein 1; predicted protein of HQ2893; zinc
                     finger MYND domain-containing protein 8; cutaneous T-cell
                     lymphoma-associated antigen se14-3; transcription
                     coregulator ZMYND8; MYND-type zinc finger-containing
                     chromatin reader ZMYND8"
                     /codon_start=1
                     /product="MYND-type zinc finger-containing chromatin
                     reader ZMYND8 isoform o"
                     /protein_id="NP_001268710.1"
                     /db_xref="GeneID:23613"
                     /db_xref="HGNC:HGNC:9397"
                     /db_xref="MIM:615713"
                     /translation="MHPQSLAEEEIKTEQEVVEGMDISTRSKDPGSAERTAQKRKFPS
                     PPHSSNGHSPQDTSTSPIKKKKKPGLLNSNNKEQDGRNDFYCWVCHREGQVLCCELCP
                     RVYHAKCLRLTSEPEGDWFCPECEKITVAECIETQSKAMTMLTIEQLSYLLKFAIQKM
                     KQPGTDAFQKPVPLEQHPDYAEYIFHPMDLCTLEKNAKKKMYGCTEAFLADAKWILHN
                     CIIYNGGNHKLTQIAKVVIKICEHEMNEIEVCPECYLAACQKRDNWFCEPCSNPHPLV
                     WAKLKGFPFWPAKALRDKDGQVDARFFGQHDRAWVPINNCYLMSKEIPFSVKKTKSIF
                     NSAMQEMEVYVENIRRKFGVFNYSPFRTPYTPNSQYQMLLDPTNPSAGTAKIDKQEKV
                     KLNFDMTASPKILMSKPVLSGGTGRRISLSDMPRSPMSTNSSVHTGSDVEQDAEKKAT
                     SSHFSASEESMDFLDKSTDRSKAEMDLKELSESVQQQSTPVPLISPKRQIRSRFQLNL
                     DKTIESCKAQLGINEISEDVYTAVEHSDSEDSEKSDSSDSEYISDDEQKSKNEPEDTE
                     DKEGCQMDKEPSAVKKKPKPTNPVEIKEELKSTSPASEKADPGAVKDKASPEPEKDFS
                     EKAKPSPHPIKDKLKGKDETDSPTVHLGLDSDSESELVIDLGEDHSGREGRKNKKEPK
                     EPSPKQDVVGKTPPSTTVGSHSPPETPVLTRSSAQTSAAGATATTSTSSTVTVTAPAP
                     AATGSPVKKQRPLLPKETAPAVQRVVWNSSTVQQKEITQSPSTSTITLVTSTQSSPLV
                     TSSGSMSTLVSSVNADLPIATASADVAADIAKYTSKMMDAIKGTMTEIYNDLSKNTTG
                     STIAEIRRLRIEIEKLQWLHQQELSEMKHNLELTMAEMRQSLEQERDRLIAEVKKQLE
                     LEKQQAVDETKKKQWCANCKKEAIFYCCWNTSYCDYPCQQAHWPEHMKSCTQSATAPQ
                     QEADAEVNTETLNKSSQGSSSSTQSAPSETASASKEKETSAEKSKESGSTLDLSGSRE
                     TPSSILLGSNQGSDHSRSNKSSWSSSDEKRGSTRSDHNTSTSTKSLLPKESRLDTFWD
                     "
     exon            44..114
                     /gene="ZMYND8"
                     /gene_synonym="PRKCBP1; PRO2893; RACK7"
                     /inference="alignment:Splign:2.1.0"
     exon            115..263
                     /gene="ZMYND8"
                     /gene_synonym="PRKCBP1; PRO2893; RACK7"
                     /inference="alignment:Splign:2.1.0"
     exon            264..407
                     /gene="ZMYND8"
                     /gene_synonym="PRKCBP1; PRO2893; RACK7"
                     /inference="alignment:Splign:2.1.0"
     exon            408..521
                     /gene="ZMYND8"
                     /gene_synonym="PRKCBP1; PRO2893; RACK7"
                     /inference="alignment:Splign:2.1.0"
     exon            522..614
                     /gene="ZMYND8"
                     /gene_synonym="PRKCBP1; PRO2893; RACK7"
                     /inference="alignment:Splign:2.1.0"
     exon            615..702
                     /gene="ZMYND8"
                     /gene_synonym="PRKCBP1; PRO2893; RACK7"
                     /inference="alignment:Splign:2.1.0"
     exon            703..758
                     /gene="ZMYND8"
                     /gene_synonym="PRKCBP1; PRO2893; RACK7"
                     /inference="alignment:Splign:2.1.0"
     exon            759..836
                     /gene="ZMYND8"
                     /gene_synonym="PRKCBP1; PRO2893; RACK7"
                     /inference="alignment:Splign:2.1.0"
     exon            837..952
                     /gene="ZMYND8"
                     /gene_synonym="PRKCBP1; PRO2893; RACK7"
                     /inference="alignment:Splign:2.1.0"
     exon            953..1434
                     /gene="ZMYND8"
                     /gene_synonym="PRKCBP1; PRO2893; RACK7"
                     /inference="alignment:Splign:2.1.0"
     exon            1435..1587
                     /gene="ZMYND8"
                     /gene_synonym="PRKCBP1; PRO2893; RACK7"
                     /inference="alignment:Splign:2.1.0"
     exon            1588..2097
                     /gene="ZMYND8"
                     /gene_synonym="PRKCBP1; PRO2893; RACK7"
                     /inference="alignment:Splign:2.1.0"
     exon            2098..2340
                     /gene="ZMYND8"
                     /gene_synonym="PRKCBP1; PRO2893; RACK7"
                     /inference="alignment:Splign:2.1.0"
     exon            2341..2531
                     /gene="ZMYND8"
                     /gene_synonym="PRKCBP1; PRO2893; RACK7"
                     /inference="alignment:Splign:2.1.0"
     exon            2532..2612
                     /gene="ZMYND8"
                     /gene_synonym="PRKCBP1; PRO2893; RACK7"
                     /inference="alignment:Splign:2.1.0"
     exon            2613..2691
                     /gene="ZMYND8"
                     /gene_synonym="PRKCBP1; PRO2893; RACK7"
                     /inference="alignment:Splign:2.1.0"
     exon            2692..2931
                     /gene="ZMYND8"
                     /gene_synonym="PRKCBP1; PRO2893; RACK7"
                     /inference="alignment:Splign:2.1.0"
     exon            2932..3092
                     /gene="ZMYND8"
                     /gene_synonym="PRKCBP1; PRO2893; RACK7"
                     /inference="alignment:Splign:2.1.0"
     exon            3093..3159
                     /gene="ZMYND8"
                     /gene_synonym="PRKCBP1; PRO2893; RACK7"
                     /inference="alignment:Splign:2.1.0"
     exon            3160..4843
                     /gene="ZMYND8"
                     /gene_synonym="PRKCBP1; PRO2893; RACK7"
                     /inference="alignment:Splign:2.1.0"
     regulatory      4686..4691
                     /regulatory_class="polyA_signal_sequence"
                     /gene="ZMYND8"
                     /gene_synonym="PRKCBP1; PRO2893; RACK7"
                     /note="hexamer: ATTAAA"
     polyA_site      4708
                     /gene="ZMYND8"
                     /gene_synonym="PRKCBP1; PRO2893; RACK7"
                     /note="major polyA site"
     regulatory      4821..4826
                     /regulatory_class="polyA_signal_sequence"
                     /gene="ZMYND8"
                     /gene_synonym="PRKCBP1; PRO2893; RACK7"
                     /note="hexamer: ATTAAA"
     polyA_site      4843
                     /gene="ZMYND8"
                     /gene_synonym="PRKCBP1; PRO2893; RACK7"
                     /note="major polyA site"
ORIGIN      
        1 ataagtattg acattacaca gtgttaacaa tgcatccaca gagcttggct gaagaggaaa
       61 taaaaacaga acaggaggtg gtagagggca tggatatctc tactcgctcc aaagatcctg
      121 gctctgcaga gagaacagcc cagaaaagaa agttccccag ccctccacat tcttccaatg
      181 gccactcgcc gcaggacaca tcaacaagcc ccattaaaaa gaaaaagaaa cctggcttac
      241 tgaacagtaa caataaggag caggatggac ggaatgattt ctactgctgg gtttgtcacc
      301 gggaaggcca agtcctttgc tgtgagctct gtccccgggt ttatcacgct aagtgtctga
      361 gactgacatc ggaaccagag ggggactggt tttgtcctga atgtgagaaa attacagtag
      421 cagaatgcat cgagacccag agtaaagcca tgacaatgct caccattgaa cagttatcct
      481 acctgctcaa gtttgccatt cagaaaatga aacagccagg gacagatgca ttccagaagc
      541 ccgttccatt ggaacagcac cctgactatg cggaatacat cttccatcca atggaccttt
      601 gtacattgga aaagaatgcg aaaaagaaaa tgtatggctg cacagaagcc ttcctggctg
      661 atgcaaagtg gattttgcac aactgcatca tttataatgg gggaaatcac aaattgacgc
      721 aaatagcgaa agtagtcatc aaaatctgtg aacatgagat gaatgaaatc gaagtatgtc
      781 cagaatgtta tctagctgct tgccaaaaac gagataactg gttttgtgag ccttgtagca
      841 atccacatcc tttggtctgg gccaaactga aggggtttcc attctggcct gcaaaagctc
      901 taagggataa agacgggcag gtcgatgccc gattctttgg acaacatgac agggcctggg
      961 ttccaataaa taattgctac ctcatgtcta aagaaattcc tttttctgtg aaaaagacta
     1021 agagcatctt caacagtgcc atgcaagaga tggaggttta cgtggagaac atccgcagga
     1081 agtttggggt ttttaattac tctccattta ggacacccta cacacccaac agccagtatc
     1141 aaatgctgct cgatcccacc aaccccagcg ccggcactgc caagatagac aagcaggaga
     1201 aggtcaagct caactttgac atgacggcat cccccaagat cctgatgagc aagcctgtgc
     1261 tgagtggggg cacaggccgc cggatttcct tgtcggatat gccgcgctcc cccatgagca
     1321 caaactcttc tgtgcacacg ggctccgacg tggagcagga tgctgagaag aaggccacgt
     1381 cgagccactt cagtgcgagc gaggagtcca tggacttcct ggataagagc acagatcgaa
     1441 gcaaagctga gatggatttg aaggagctga gcgagtcggt ccagcaacag tccacccctg
     1501 ttcctctcat ctctcccaag cgccagattc gtagcaggtt ccagctgaat cttgacaaga
     1561 ccatagagag ttgcaaagca caattaggca taaatgaaat ctcggaagat gtctatacgg
     1621 ccgtagagca cagcgattcg gaggattctg agaagtcaga tagtagcgat agtgagtata
     1681 tcagtgatga tgagcagaag tctaagaacg agccagaaga cacagaggac aaagaaggtt
     1741 gtcagatgga caaagagcca tctgctgtta aaaaaaagcc caagcctaca aacccagtgg
     1801 agattaaaga ggagctgaaa agcacgtcac cagccagcga gaaggcagac cctggagcag
     1861 tcaaggacaa ggccagccct gagcctgaga aggacttttc cgaaaaggca aaaccttcac
     1921 ctcaccccat aaaggataaa ctgaagggaa aagatgagac ggattcccca acagtccatt
     1981 tgggcctgga ctctgattca gagagcgaac ttgtcataga tttaggagaa gaccattctg
     2041 ggcgggaggg tcgaaaaaat aagaaggaac ccaaagaacc atctcccaaa caggatgttg
     2101 taggtaaaac tccaccatcc acgacggtgg gcagccattc tcccccggaa acaccggtgc
     2161 tcacccgctc ttccgcccaa acttccgcgg ctggcgccac agccaccacc agcacgtcct
     2221 ccacggtcac cgtcacggcc ccggcccccg ccgccacagg aagcccagtg aaaaagcaga
     2281 ggccgctttt accgaaggag actgccccgg ccgtgcagcg ggtcgtgtgg aactcatcaa
     2341 ctgtccagca gaaggagatc acacagagcc catccacgtc caccatcacc ctggtgacca
     2401 gcacacagtc atcgcccctg gtcaccagct cggggtccat gagcaccctt gtgtcctcag
     2461 tcaacgctga cctgcccatc gccactgcct cagctgatgt cgccgctgat attgccaagt
     2521 acactagcaa aatgatggat gcaataaaag gaacaatgac agaaatatac aacgatcttt
     2581 ctaaaaacac tactggaagc acaatagctg agattcgcag gctgaggatc gagatagaga
     2641 agctccagtg gctgcaccag caagagctct ccgaaatgaa acacaactta gagctgacca
     2701 tggcggagat gcggcagagc ctggagcagg agcgggaccg gctcatcgcc gaggtgaaga
     2761 agcagctgga gttggagaag cagcaggcgg tggatgagac caagaagaag cagtggtgcg
     2821 ccaactgcaa gaaggaggcc atcttttact gctgttggaa caccagctac tgtgactacc
     2881 cctgccagca agcccactgg cctgagcaca tgaagtcctg cacccagtca gctactgctc
     2941 ctcagcagga agcggatgct gaggtgaaca cagaaacact aaataagtcc tcccagggga
     3001 gctcctcgag cacacaatca gcaccttcag aaacggccag cgcctccaaa gagaaggaga
     3061 cgtcagctga gaaaagcaag gagagtggct cgacccttga cctttctggc tccagagaga
     3121 cgccctcctc cattctctta ggctccaacc aaggctctga ccattcccgg agtaataaat
     3181 ccagttggag cagcagtgat gagaagaggg gatcgacacg ttccgatcac aacaccagta
     3241 ccagcacgaa gagcctcctc ccgaaagagt ctcggctgga caccttctgg gactagcagt
     3301 gaatcgggac acaaaccacc caccccattg ggagaaaaac ccagacgcca ggaaaagaag
     3361 aaacaacaaa ggcaggagaa cagccacttt cagacttgaa aatgacaaaa ccctcagttg
     3421 agcctgagcc cccggcgcgg gggctgctac actacaggac acccagcatc ggctttgact
     3481 gcagactgtt cacccacacg agccctgtgc ttttggtgta aataatgtac aatttgtgga
     3541 tgtcattgaa tctagaggac tttccccttt ttatatttgt attaacttta acttattaaa
     3601 aaaaaaaaaa gaaaaagaaa aacgatttaa aaaaaaaaaa aaaagcaacc aaccccaaca
     3661 acaaaaaaga atgttttggt attggagaag ggatggtcag ttagcctgtc tgtcacacga
     3721 cggaatggat actgggcccg gggaccactt tcatactcac gtcctcatcc ttggataccc
     3781 aggggagggc gaaccgtttt cgctcgtgtg tctgtacgca gcatgttggg atcgggagtt
     3841 tcggcacaga ctatcccatc aagccgttgg ctcctttcag ctactacgtt accacgttcc
     3901 taaaacgcaa gctctccgga ccagacggac acagggagaa gctagtttct ttcatgtgat
     3961 tgaaatgatg actctactcc taaaagggaa aaaacaatat ccttgtttac agaagagaaa
     4021 caaacaagcc ccactcagct cagtcacagg agagaacaca gaaagtctta ggatcatgaa
     4081 ctctgaaaaa aagagaaacc ttatctttgc tttgtggttc ctttaaacac actcacacac
     4141 acttggtcag agatgctgtg cttcttggaa gcaaggactc aaaggcaagg tgcacgcaga
     4201 ggacgtttga gtctgggatg aagcatgtac gtattattta tatgatggaa tttcacgttt
     4261 ttatgtaagc atgaaacaca ggcagtatga gagaaagcaa ggcccgtcat gctgtccgta
     4321 cactacgtat gctgtagagc cattttgtat gttgtgtaaa acaaaaagca ttgatgaaaa
     4381 agcaaaaggt gatgtatgta tatgagaaaa ttaattgtac gatatcattc cagtacgttt
     4441 tgttgtacat tttagtcttg tttactttct cttcattgtt aagaggatgc gaactgtaca
     4501 gtttccagct agttacccat attagagaag aaataagaga gtattagaag aaaacaggag
     4561 agaaagaaca tttgtgaatt gcagttgtca aaaaaaaaaa atagcctagc tggccttatt
     4621 tgtgaagcat aattgctttt agcatatgga agtatttttt cacattttct ttgtataaaa
     4681 tttgtattaa acttaaatat ctttttgatg gtggtgtttc tttgtgactg agccagtaga
     4741 ctcacactat atgctttttt gggtttgccc gttccttccc ccaccccccc agttttttca
     4801 gatttcttta ccttttttta attaaactgt tttggaaaaa tgc
//
