LOCUS       NM_138462               1395 bp    mRNA    linear   PRI 20-SEP-2024
DEFINITION  Homo sapiens zinc finger MYND-type containing 19 (ZMYND19), mRNA.
ACCESSION   NM_138462
VERSION     NM_138462.3
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 1395)
  AUTHORS   Huttlin,E.L., Bruckner,R.J., Navarrete-Perea,J., Cannon,J.R.,
            Baltier,K., Gebreab,F., Gygi,M.P., Thornock,A., Zarraga,G., Tam,S.,
            Szpyt,J., Gassaway,B.M., Panov,A., Parzen,H., Fu,S., Golbazi,A.,
            Maenpaa,E., Stricker,K., Guha Thakurta,S., Zhang,T., Rad,R.,
            Pan,J., Nusinow,D.P., Paulo,J.A., Schweppe,D.K., Vaites,L.P.,
            Harper,J.W. and Gygi,S.P.
  TITLE     Dual proteome-scale networks reveal cell-specific remodeling of the
            human interactome
  JOURNAL   Cell 184 (11), 3022-3040 (2021)
   PUBMED   33961781
REFERENCE   2  (bases 1 to 1395)
  AUTHORS   Luck,K., Kim,D.K., Lambourne,L., Spirohn,K., Begg,B.E., Bian,W.,
            Brignall,R., Cafarelli,T., Campos-Laborie,F.J., Charloteaux,B.,
            Choi,D., Cote,A.G., Daley,M., Deimling,S., Desbuleux,A., Dricot,A.,
            Gebbia,M., Hardy,M.F., Kishore,N., Knapp,J.J., Kovacs,I.A.,
            Lemmens,I., Mee,M.W., Mellor,J.C., Pollis,C., Pons,C.,
            Richardson,A.D., Schlabach,S., Teeking,B., Yadav,A., Babor,M.,
            Balcha,D., Basha,O., Bowman-Colin,C., Chin,S.F., Choi,S.G.,
            Colabella,C., Coppin,G., D'Amata,C., De Ridder,D., De Rouck,S.,
            Duran-Frigola,M., Ennajdaoui,H., Goebels,F., Goehring,L., Gopal,A.,
            Haddad,G., Hatchi,E., Helmy,M., Jacob,Y., Kassa,Y., Landini,S.,
            Li,R., van Lieshout,N., MacWilliams,A., Markey,D., Paulson,J.N.,
            Rangarajan,S., Rasla,J., Rayhan,A., Rolland,T., San-Miguel,A.,
            Shen,Y., Sheykhkarimli,D., Sheynkman,G.M., Simonovsky,E., Tasan,M.,
            Tejeda,A., Tropepe,V., Twizere,J.C., Wang,Y., Weatheritt,R.J.,
            Weile,J., Xia,Y., Yang,X., Yeger-Lotem,E., Zhong,Q., Aloy,P.,
            Bader,G.D., De Las Rivas,J., Gaudet,S., Hao,T., Rak,J.,
            Tavernier,J., Hill,D.E., Vidal,M., Roth,F.P. and Calderwood,M.A.
  TITLE     A reference map of the human binary protein interactome
  JOURNAL   Nature 580 (7803), 402-408 (2020)
   PUBMED   32296183
REFERENCE   3  (bases 1 to 1395)
  AUTHORS   Yu,H., Tardivo,L., Tam,S., Weiner,E., Gebreab,F., Fan,C.,
            Svrzikapa,N., Hirozane-Kishikawa,T., Rietman,E., Yang,X.,
            Sahalie,J., Salehi-Ashtiani,K., Hao,T., Cusick,M.E., Hill,D.E.,
            Roth,F.P., Braun,P. and Vidal,M.
  TITLE     Next-generation sequencing to generate interactome datasets
  JOURNAL   Nat Methods 8 (6), 478-480 (2011)
   PUBMED   21516116
REFERENCE   4  (bases 1 to 1395)
  AUTHORS   Francke,F., Buck,F. and Bachner,D.
  TITLE     MYND domain specific interaction of the melanin-concentrating
            hormone receptor 1 interacting zinc-finger protein with alpha- and
            beta-tubulin
  JOURNAL   Biochem Biophys Res Commun 334 (4), 1292-1298 (2005)
   PUBMED   16039987
  REMARK    GeneRIF: Our results suggest that MIZIP might play an important
            role in mammalian cells by associating with tubulin and thus might
            provide a link between MCHR1 and tubulin functions.
REFERENCE   5  (bases 1 to 1395)
  AUTHORS   Bachner,D., Kreienkamp,H.J. and Richter,D.
  TITLE     MIZIP, a highly conserved, vertebrate specific
            melanin-concentrating hormone receptor 1 interacting zinc-finger
            protein
  JOURNAL   FEBS Lett 526 (1-3), 124-128 (2002)
   PUBMED   12208518
  REMARK    GeneRIF: was identified from human brain and interacts with the
            C-terminus of melanin-concentrating hormone receptor 1
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL365502.57, BU147462.1 and AJ298882.2.
            
            On Nov 22, 2018 this sequence version replaced NM_138462.2.
            
            Summary: ZMYND19 is a MYND zinc finger domain-containing protein
            that binds to the C terminus of melanin-concentrating hormone
            receptor-1 (MCHR1; MIM 601751) (Bachner et al., 2002 [PubMed
            12208518]), and to the N termini of alpha-tubulin (TUBA1; MIM
            191110), and beta-tubulin (TUBB; MIM 191130) (Francke et al., 2005
            [PubMed 16039987]).[supplied by OMIM, Mar 2008].
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR1163657.295999.1, AJ298882.2
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN03465402 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000298585.3/ ENSP00000298585.2
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-27                AL365502.57        145187-145213       c
            28-32               BU147462.1         1-5
            33-1395             AJ298882.2         14-1376
FEATURES             Location/Qualifiers
     source          1..1395
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="9"
                     /map="9q34.3"
     gene            1..1395
                     /gene="ZMYND19"
                     /gene_synonym="MIZIP"
                     /note="zinc finger MYND-type containing 19"
                     /db_xref="GeneID:116225"
                     /db_xref="HGNC:HGNC:21146"
                     /db_xref="MIM:611424"
     exon            1..300
                     /gene="ZMYND19"
                     /gene_synonym="MIZIP"
                     /inference="alignment:Splign:2.1.0"
     CDS             250..933
                     /gene="ZMYND19"
                     /gene_synonym="MIZIP"
                     /note="melanin-concentrating hormone receptor 1
                     interacting zinc-finger protein; zinc finger, MYND domain
                     containing 19; MCH-R1-interacting zinc finger protein"
                     /codon_start=1
                     /product="zinc finger MYND domain-containing protein 19"
                     /protein_id="NP_612471.1"
                     /db_xref="CCDS:CCDS7048.1"
                     /db_xref="GeneID:116225"
                     /db_xref="HGNC:HGNC:21146"
                     /db_xref="MIM:611424"
                     /translation="MTDFKLGIVRLGRVAGKTKYTLIDEQDIPLVESYSFEARMEVDA
                     DGNGAKIFAYAFDKNRGRGSGRLLHELLWERHRGGVAPGFQVVHLNAVTVDNRLDNLQ
                     LVPWGWRPKAEETSSKQREQSLYWLAIQQLPTDPIEEQFPVLNVTRYYNANGDVVEEE
                     ENSCTYYECHYPPCTVIEKQLREFNICGRCQVARYCGSQCQQKDWPAHKKHCRERKRP
                     FQHELEPER"
     exon            301..360
                     /gene="ZMYND19"
                     /gene_synonym="MIZIP"
                     /inference="alignment:Splign:2.1.0"
     exon            361..467
                     /gene="ZMYND19"
                     /gene_synonym="MIZIP"
                     /inference="alignment:Splign:2.1.0"
     exon            468..608
                     /gene="ZMYND19"
                     /gene_synonym="MIZIP"
                     /inference="alignment:Splign:2.1.0"
     exon            609..789
                     /gene="ZMYND19"
                     /gene_synonym="MIZIP"
                     /inference="alignment:Splign:2.1.0"
     exon            790..1395
                     /gene="ZMYND19"
                     /gene_synonym="MIZIP"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1235..1240
                     /regulatory_class="polyA_signal_sequence"
                     /gene="ZMYND19"
                     /gene_synonym="MIZIP"
                     /note="hexamer: AATAGA"
     polyA_site      1262
                     /gene="ZMYND19"
                     /gene_synonym="MIZIP"
                     /note="major polyA site"
     polyA_site      1292
                     /gene="ZMYND19"
                     /gene_synonym="MIZIP"
                     /note="major polyA site"
     regulatory      1378..1383
                     /regulatory_class="polyA_signal_sequence"
                     /gene="ZMYND19"
                     /gene_synonym="MIZIP"
                     /note="hexamer: AGTAAA"
     polyA_site      1395
                     /gene="ZMYND19"
                     /gene_synonym="MIZIP"
                     /note="major polyA site"
ORIGIN      
        1 gctccgctcg ctgtggtgcg cgcggtggcg gtggcggcgg cggcggcggc gcgtggcagg
       61 tccggcgggc gcgaggcggc ggcggaggcc cgagcccggc ccagcctcgt cccgcccgga
      121 gcccgcctgg ctgctacccc gaccccggct ccggtcccgt cctgtcccgg cgcgccgcgg
      181 cctcgccccg gcccccgctc ggcgcctccc gagggagcgg cgctgccggc cgagagcgca
      241 ggcccggcca tgaccgactt caaattgggt atcgtgcggc tcggccgggt ggccgggaag
      301 accaaataca cgctgatcga tgagcaggac atcccgctgg tggagagcta ctcctttgag
      361 gcccgaatgg aagtggatgc agatggaaat ggtgctaaga tatttgccta tgcctttgac
      421 aagaaccgag gaaggggctc tgggagactc cttcatgagc tgctgtggga gcggcaccgg
      481 gggggcgtgg ccccgggctt ccaggtggtg cacctcaacg ctgtgaccgt ggacaatcgc
      541 ctggacaacc tgcaactggt gccgtggggc tggcggccca aggctgaaga gacctccagc
      601 aagcagaggg agcaaagctt gtattggctt gcaattcagc agctgcctac agaccctata
      661 gaagaacagt ttcctgtcct aaatgtgacc cggtattata atgccaacgg ggatgtagtg
      721 gaagaggagg agaactcttg cacctactat gagtgccact accctccctg cacagtgatt
      781 gagaagcagc tccgggagtt caacatctgt gggcgctgcc aggtggcccg gtactgcggc
      841 tcccagtgcc agcagaagga ctggcctgcc cacaagaagc actgtcggga gaggaagcgt
      901 cccttccagc atgagcttga gccagagcga tgacgggcag gggagccaca catactcaca
      961 gcccccgggc tctaccctgg gcacagcaga gacagactgg tggttgaacc tggaggtgcc
     1021 aaaaaagcca gctgcgggcc caggacagct gccgtgagac tcccgatgtc acaggcagtc
     1081 tgtgtggtta cagcgcccct cagtgttcat ctccagcaga gacaacggag gaggctccca
     1141 ccaggacggt tctcattatt tatatgttaa tatgtttgta aactcatgta cagttttttt
     1201 tgggggggag gcaatgggaa gggtagaaat tacaaataga atcatttgct gtaatcctta
     1261 aatggcaaac ggtcaggcca cgtgactaaa aactgtcctg ttgtcgaagc ttctcccctg
     1321 ggccgccggg agccccgtgg agcgcggcct gcacgggagt tgtgtccaca aaggcaaagt
     1381 aaaggggtgg aatca
//
