LOCUS       NM_007167               5122 bp    mRNA    linear   PRI 11-FEB-2025
DEFINITION  Homo sapiens zinc finger MYM-type containing 6 (ZMYM6), mRNA.
ACCESSION   NM_007167
VERSION     NM_007167.4
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 5122)
  AUTHORS   Huttlin,E.L., Bruckner,R.J., Navarrete-Perea,J., Cannon,J.R.,
            Baltier,K., Gebreab,F., Gygi,M.P., Thornock,A., Zarraga,G., Tam,S.,
            Szpyt,J., Gassaway,B.M., Panov,A., Parzen,H., Fu,S., Golbazi,A.,
            Maenpaa,E., Stricker,K., Guha Thakurta,S., Zhang,T., Rad,R.,
            Pan,J., Nusinow,D.P., Paulo,J.A., Schweppe,D.K., Vaites,L.P.,
            Harper,J.W. and Gygi,S.P.
  TITLE     Dual proteome-scale networks reveal cell-specific remodeling of the
            human interactome
  JOURNAL   Cell 184 (11), 3022-3040 (2021)
   PUBMED   33961781
REFERENCE   2  (bases 1 to 5122)
  AUTHORS   Haenig,C., Atias,N., Taylor,A.K., Mazza,A., Schaefer,M.H., Russ,J.,
            Riechers,S.P., Jain,S., Coughlin,M., Fontaine,J.F., Freibaum,B.D.,
            Brusendorf,L., Zenkner,M., Porras,P., Stroedicke,M., Schnoegl,S.,
            Arnsburg,K., Boeddrich,A., Pigazzini,L., Heutink,P., Taylor,J.P.,
            Kirstein,J., Andrade-Navarro,M.A., Sharan,R. and Wanker,E.E.
  TITLE     Interactome Mapping Provides a Network of Neurodegenerative Disease
            Proteins and Uncovers Widespread Protein Aggregation in Affected
            Brains
  JOURNAL   Cell Rep 32 (7), 108050 (2020)
   PUBMED   32814053
REFERENCE   3  (bases 1 to 5122)
  AUTHORS   Luck,K., Kim,D.K., Lambourne,L., Spirohn,K., Begg,B.E., Bian,W.,
            Brignall,R., Cafarelli,T., Campos-Laborie,F.J., Charloteaux,B.,
            Choi,D., Cote,A.G., Daley,M., Deimling,S., Desbuleux,A., Dricot,A.,
            Gebbia,M., Hardy,M.F., Kishore,N., Knapp,J.J., Kovacs,I.A.,
            Lemmens,I., Mee,M.W., Mellor,J.C., Pollis,C., Pons,C.,
            Richardson,A.D., Schlabach,S., Teeking,B., Yadav,A., Babor,M.,
            Balcha,D., Basha,O., Bowman-Colin,C., Chin,S.F., Choi,S.G.,
            Colabella,C., Coppin,G., D'Amata,C., De Ridder,D., De Rouck,S.,
            Duran-Frigola,M., Ennajdaoui,H., Goebels,F., Goehring,L., Gopal,A.,
            Haddad,G., Hatchi,E., Helmy,M., Jacob,Y., Kassa,Y., Landini,S.,
            Li,R., van Lieshout,N., MacWilliams,A., Markey,D., Paulson,J.N.,
            Rangarajan,S., Rasla,J., Rayhan,A., Rolland,T., San-Miguel,A.,
            Shen,Y., Sheykhkarimli,D., Sheynkman,G.M., Simonovsky,E., Tasan,M.,
            Tejeda,A., Tropepe,V., Twizere,J.C., Wang,Y., Weatheritt,R.J.,
            Weile,J., Xia,Y., Yang,X., Yeger-Lotem,E., Zhong,Q., Aloy,P.,
            Bader,G.D., De Las Rivas,J., Gaudet,S., Hao,T., Rak,J.,
            Tavernier,J., Hill,D.E., Vidal,M., Roth,F.P. and Calderwood,M.A.
  TITLE     A reference map of the human binary protein interactome
  JOURNAL   Nature 580 (7803), 402-408 (2020)
   PUBMED   32296183
REFERENCE   4  (bases 1 to 5122)
  AUTHORS   Hayward,A., Ghazal,A., Andersson,G., Andersson,L. and Jern,P.
  TITLE     ZBED evolution: repeated utilization of DNA transposons as
            regulators of diverse host functions
  JOURNAL   PLoS One 8 (3), e59940 (2013)
   PUBMED   23533661
REFERENCE   5  (bases 1 to 5122)
  AUTHORS   Bai,S.W., Herrera-Abreu,M.T., Rohn,J.L., Racine,V., Tajadura,V.,
            Suryavanshi,N., Bechtel,S., Wiemann,S., Baum,B. and Ridley,A.J.
  TITLE     Identification and characterization of a set of conserved and new
            regulators of cytoskeletal organization, cell morphology and
            migration
  JOURNAL   BMC Biol 9, 54 (2011)
   PUBMED   21834987
  REMARK    Erratum:[BMC Biol. 2024 Oct 10;22(1):228. doi:
            10.1186/s12915-024-02036-3.. PMID: 39390519]
            Publication Status: Online-Only
REFERENCE   6  (bases 1 to 5122)
  AUTHORS   Smedley,D., Hamoudi,R., Lu,Y.J., Cooper,C. and Shipley,J.
  TITLE     Cloning and mapping of members of the MYM family
  JOURNAL   Genomics 60 (2), 244-247 (1999)
   PUBMED   10486218
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BC068534.1, BC107880.1 and AL833263.1.
            
            On Nov 24, 2018 this sequence version replaced NM_007167.3.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR1660803.122074.1,
                                           SRR1660805.52459.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA1965299,
                                           SAMEA1966682 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000357182.9/ ENSP00000349708.4
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-335               BC068534.1         24-358
            336-2406            BC107880.1         340-2410
            2407-5122           AL833263.1         3526-6241
FEATURES             Location/Qualifiers
     source          1..5122
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="1"
                     /map="1p34.3"
     gene            1..5122
                     /gene="ZMYM6"
                     /gene_synonym="Buster2; MYM; ZBED7; ZNF198L4; ZNF258"
                     /note="zinc finger MYM-type containing 6"
                     /db_xref="GeneID:9204"
                     /db_xref="HGNC:HGNC:13050"
                     /db_xref="MIM:613567"
     exon            1..131
                     /gene="ZMYM6"
                     /gene_synonym="Buster2; MYM; ZBED7; ZNF198L4; ZNF258"
                     /inference="alignment:Splign:2.1.0"
     exon            132..298
                     /gene="ZMYM6"
                     /gene_synonym="Buster2; MYM; ZBED7; ZNF198L4; ZNF258"
                     /inference="alignment:Splign:2.1.0"
     CDS             206..4183
                     /gene="ZMYM6"
                     /gene_synonym="Buster2; MYM; ZBED7; ZNF198L4; ZNF258"
                     /note="zinc finger protein 258; transposon-derived Buster2
                     transposase-like protein; zinc finger, BED-type containing
                     7; zinc finger, MYM-type 6"
                     /codon_start=1
                     /product="zinc finger MYM-type protein 6"
                     /protein_id="NP_009098.3"
                     /db_xref="CCDS:CCDS387.2"
                     /db_xref="GeneID:9204"
                     /db_xref="HGNC:HGNC:13050"
                     /db_xref="MIM:613567"
                     /translation="MKEPLDGECGKAVVPQQELLDKIKEEPDNAQEYGCVQQPKTQES
                     KLKIGGVSSVNERPIAQQLNPGFQLSFASSGPSVLLPSVPAVAIKVFCSGCKKMLYKG
                     QTAYHKTGSTQLFCSTRCITRHSSPACLPPPPKKTCTNCSKDILNPKDVITTRFENSY
                     PSKDFCSQSCLSSYELKKKPVVTIYTKSISTKCSMCQKNADTRFEVKYQNVVHGLCSD
                     ACFSKFHSTNNLTMNCCENCGSYCYSSSGPCQSQKVFSSTSVTAYKQNSAQIPPYALG
                     KSLRPSAEMIETTNDSGKTELFCSINCLSAYRVKTVTSSGVQVSCHSCKTSAIPQYHL
                     AMSNGTIYSFCSSSCVVAFQNVFSKPKGTNSSAVPLSQGQVVVSPPSSRSAVSIGGGN
                     TSAVSPSSIRGSAAASLQPLAEQSQQVALTHTVVKLKCQHCNHLFATKPELLFYKGKM
                     FLFCGKNCSDEYKKKNKVVAMCDYCKLQKIIKETVRFSGVDKPFCSEVCKFLSARDFG
                     ERWGNYCKMCSYCSQTSPNLVENRLEGKLEEFCCEDCMSKFTVLFYQMAKCDGCKRQG
                     KLSESIKWRGNIKHFCNLFCVLEFCHQQIMNDCLPQNKVNISKAKTAVTELPSARTDT
                     TPVITSVMSLAKIPATLSTGNTNSVLKGAVTKEAAKIIQDESTQEDAMKFPSSQSSQP
                     SRLLKNKGISCKPVTQTKATSCKPHTQHKECQTDLPMPNEKNDAELDSPPSKKKRLGF
                     FQTYDTEYLKVGFIICPGSKESSPRPQCVICGEILSSENMKPANLSHHLKTKHSELEN
                     KPVDFFEQKSLEMECQNSSLKKCLLVEKSLVKASYLIAFQTAASKKPFSIAEELIKPY
                     LVEMCSEVLGSSAGDKMKTIPLSNVTIQHRIDELSADIEDQLIQKVRESKWFALQIDE
                     SSEISNITLLLCYIRFIDYDCRDVKEELLFCIEMPTQITGFEIFELINKYIDSKSLNW
                     KHCVGLCTDGAASMTGRYSGLKAKIQEVAMNTAAFTHCFIHRERLVAEKLSPCLHKIL
                     LQSAQILSFIKSNALNSRMLTILCEEMGSEHVSLPLHAEVRWISRGRMLKRLFELRHE
                     IEIFLSQKHSDLAKYFHDEEWVGKLAYLSDIFSLINELNLSLQGTLTTFFNLCNKIDV
                     FKRKLKMWLKRTQENDYDMFPSFSEFSNSSGLNMTDITRIIFEHLEGLSQVFSDCFPP
                     EQDLRSGNLWIIHPFMNHQNNNLTDFEEEKLTELSSDLGLQALFKSVSVTQFWINAKT
                     SYPELHERAMKFLLPFSTVYLCDAAFSALTESKQKNLLGSGPALRLAVTSLIPRIEKL
                     VKEKE"
     exon            299..383
                     /gene="ZMYM6"
                     /gene_synonym="Buster2; MYM; ZBED7; ZNF198L4; ZNF258"
                     /inference="alignment:Splign:2.1.0"
     exon            384..633
                     /gene="ZMYM6"
                     /gene_synonym="Buster2; MYM; ZBED7; ZNF198L4; ZNF258"
                     /inference="alignment:Splign:2.1.0"
     exon            634..808
                     /gene="ZMYM6"
                     /gene_synonym="Buster2; MYM; ZBED7; ZNF198L4; ZNF258"
                     /inference="alignment:Splign:2.1.0"
     exon            809..1000
                     /gene="ZMYM6"
                     /gene_synonym="Buster2; MYM; ZBED7; ZNF198L4; ZNF258"
                     /inference="alignment:Splign:2.1.0"
     exon            1001..1151
                     /gene="ZMYM6"
                     /gene_synonym="Buster2; MYM; ZBED7; ZNF198L4; ZNF258"
                     /inference="alignment:Splign:2.1.0"
     exon            1152..1267
                     /gene="ZMYM6"
                     /gene_synonym="Buster2; MYM; ZBED7; ZNF198L4; ZNF258"
                     /inference="alignment:Splign:2.1.0"
     exon            1268..1546
                     /gene="ZMYM6"
                     /gene_synonym="Buster2; MYM; ZBED7; ZNF198L4; ZNF258"
                     /inference="alignment:Splign:2.1.0"
     exon            1547..1697
                     /gene="ZMYM6"
                     /gene_synonym="Buster2; MYM; ZBED7; ZNF198L4; ZNF258"
                     /inference="alignment:Splign:2.1.0"
     exon            1698..1870
                     /gene="ZMYM6"
                     /gene_synonym="Buster2; MYM; ZBED7; ZNF198L4; ZNF258"
                     /inference="alignment:Splign:2.1.0"
     exon            1871..2018
                     /gene="ZMYM6"
                     /gene_synonym="Buster2; MYM; ZBED7; ZNF198L4; ZNF258"
                     /inference="alignment:Splign:2.1.0"
     exon            2019..2159
                     /gene="ZMYM6"
                     /gene_synonym="Buster2; MYM; ZBED7; ZNF198L4; ZNF258"
                     /inference="alignment:Splign:2.1.0"
     exon            2160..2197
                     /gene="ZMYM6"
                     /gene_synonym="Buster2; MYM; ZBED7; ZNF198L4; ZNF258"
                     /inference="alignment:Splign:2.1.0"
     exon            2198..2351
                     /gene="ZMYM6"
                     /gene_synonym="Buster2; MYM; ZBED7; ZNF198L4; ZNF258"
                     /inference="alignment:Splign:2.1.0"
     exon            2352..5122
                     /gene="ZMYM6"
                     /gene_synonym="Buster2; MYM; ZBED7; ZNF198L4; ZNF258"
                     /inference="alignment:Splign:2.1.0"
     regulatory      5096..5101
                     /regulatory_class="polyA_signal_sequence"
                     /gene="ZMYM6"
                     /gene_synonym="Buster2; MYM; ZBED7; ZNF198L4; ZNF258"
                     /note="hexamer: AATAAA"
     polyA_site      5122
                     /gene="ZMYM6"
                     /gene_synonym="Buster2; MYM; ZBED7; ZNF198L4; ZNF258"
                     /note="major polyA site"
ORIGIN      
        1 aggcgtggtt ggccggtcgt tgcgttggga tggatcaggc ggaattccag aagagaaaat
       61 aatccctgtc tagatgcaga ggacttggtt cctattccag tgctcctccg gtagcaggga
      121 ggcgacagaa ggtgtccaac tatccattac caagaagaaa tctattcgtt tgagcctgag
      181 acactctttg aggtaaaaaa ttagaatgaa agaacctttg gatggtgaat gtggcaaagc
      241 agtggtacca cagcaggagc ttctggacaa aattaaagaa gaaccagaca atgctcaaga
      301 gtatggatgt gtccaacagc caaaaactca agaaagtaaa ttgaaaattg gtggtgtgtc
      361 ttcagttaat gagagaccta ttgcccagca gttgaaccca ggctttcagc tttcttttgc
      421 atcatctggc ccaagtgtgt tgcttccttc agttccagct gttgctatta aggttttttg
      481 ttctggttgt aaaaaaatgc tttataaggg ccaaactgca tatcataaga caggatctac
      541 tcagctcttc tgctccacac gatgcatcac cagacattct tcacctgcct gcctgccacc
      601 tcctcccaag aaaacctgca caaactgctc gaaagacatt ttaaatccta aggatgtgat
      661 cacaactcgc tttgagaatt cctatcctag caaagatttc tgcagccaat catgcttgtc
      721 atcttatgag ctaaagaaaa aacctgttgt taccatatat accaaaagca tttcaactaa
      781 gtgcagtatg tgtcagaaga atgctgatac tcgatttgaa gttaaatatc aaaatgtggt
      841 acatggtctt tgtagtgatg cctgtttttc aaaatttcac tctacaaaca acctcaccat
      901 gaactgttgt gagaactgtg ggagctattg ctatagtagc tctggtcctt gccaatccca
      961 gaaggttttt agttcaacaa gtgtcacggc atacaagcag aattctgccc aaattcctcc
     1021 atatgccctg gggaagtcat tgaggccctc agctgaaatg attgagacta caaatgattc
     1081 aggaaaaaca gagcttttct gctctattaa ttgcttatct gcttacagag ttaagactgt
     1141 tacttcttca ggtgtccagg tttcatgtca tagttgtaaa acctcagcaa tccctcagta
     1201 tcacctagcc atgtcaaatg gaactatata cagcttctgc agctccagtt gtgtggttgc
     1261 tttccagaat gtatttagca agccaaaagg aacaaactct tcggcggtgc ccctgtctca
     1321 gggccaagtg gttgtaagcc cgccctcctc caggtcagca gtgtcaatag gaggaggtaa
     1381 cacctctgcc gtttccccca gctccatccg tggctctgct gcagccagcc tccaacctct
     1441 tgctgaacaa tcccagcaag ttgctttaac ccatacagtt gttaaactca agtgtcagca
     1501 ctgtaaccat ctatttgcca caaaaccaga acttcttttt tacaagggta aaatgtttct
     1561 gttttgtggc aagaattgct ctgatgaata caagaagaaa aataaagttg tggcaatgtg
     1621 tgactactgt aaactgcaga aaattataaa ggagactgtg cgattctcag gggttgataa
     1681 gccattctgt agtgaagttt gcaaattcct ctctgcccgt gactttggag aacgatgggg
     1741 aaactactgt aagatgtgca gctactgttc acagacatcc ccaaatttgg tagaaaatcg
     1801 attggagggc aagttagaag agttttgttg tgaagattgt atgtccaaat ttacagttct
     1861 gttttatcag atggccaagt gtgatggttg taaacgacag ggtaaactaa gcgagtccat
     1921 aaagtggcga ggcaacatta aacatttctg taacctattt tgtgtcttgg agttttgtca
     1981 tcagcaaatt atgaatgact gtcttccaca aaataaagta aatatttcta aagcaaaaac
     2041 tgctgtgacg gagctccctt ctgcaaggac agatacaaca ccagttataa ccagtgtgat
     2101 gtcattggca aaaatacctg ctaccttatc tacagggaac actaacagtg ttttaaaagg
     2161 tgcagttact aaagaggcag caaagatcat tcaagatgaa agtacacagg aagatgctat
     2221 gaaatttcca tcttcccaat cttcccagcc ttccaggctt ttaaagaaca aaggcatatc
     2281 atgcaaaccc gtcacacaga ccaaggccac ttcttgcaaa ccacatacac agcacaaaga
     2341 atgtcagaca gatttaccta tgcctaatga aaaaaatgat gcagaacttg attctccacc
     2401 ttcaaagaaa aaaagattag gttttttcca gacttatgat acagaatatt taaaagttgg
     2461 ttttattatc tgtcctggat caaaagaaag ttcaccaagg ccacagtgtg tcatttgtgg
     2521 agagatctta tccagtgaaa acatgaagcc agcaaatctt tctcatcatt tgaagacaaa
     2581 acattcagaa ttagaaaaca aaccagtaga tttttttgaa caaaaatctt tagaaatgga
     2641 atgtcaaaat agttctttaa aaaagtgttt actagttgaa aagtcacttg tgaaagcttc
     2701 ttatttaatt gctttccaaa ctgctgcaag caagaagcca ttctccattg ctgaagaatt
     2761 aattaaacca tatttagtag aaatgtgttc agaagttttg ggttcaagtg ctggagacaa
     2821 aatgaaaact attccacttt ctaatgttac aattcaacac aggattgatg aactatctgc
     2881 agacattgaa gaccagctga ttcaaaaggt cagagagtca aagtggtttg cccttcagat
     2941 agatgagtca tcagaaatct caaatatcac acttcttttg tgctatattc gtttcattga
     3001 ttatgattgt cgtgatgtaa aagaagaatt attattttgc attgaaatgc ctactcaaat
     3061 aactggcttt gaaatatttg aactaataaa taaatatatt gatagtaaat ctctgaattg
     3121 gaaacattgt gttggtctct gtaccgatgg ggctgcaagc atgactggca ggtattctgg
     3181 tttaaaagca aaaattcaag aagttgccat gaatacagcg gcatttacac attgttttat
     3241 tcaccgtgaa cgtttagtgg cagaaaagtt gtctccatgt ttacataaaa ttcttttgca
     3301 gtcagcacaa attttaagtt ttataaagag caatgcatta aattcacgta tgttaacaat
     3361 tttgtgtgaa gagatgggat ctgagcatgt gagtttaccg cttcatgctg aagtacgttg
     3421 gatatcaaga gggagaatgt taaaaagatt atttgaatta cgacatgaga ttgaaatatt
     3481 tttaagtcaa aagcattcag atttggccaa gtattttcat gatgaggaat gggttggaaa
     3541 gctggcctac ttatcagata tattttcact tataaatgaa ttaaatttaa gtctccaagg
     3601 aactttgact actttcttca atttgtgtaa taaaattgat gtatttaaga gaaagttaaa
     3661 aatgtggttg aagcgcacac aagagaatga ttatgacatg ttcccttcat tttctgaatt
     3721 ctcaaattca tcaggcttaa atatgacaga catcacaagg attatttttg agcacctgga
     3781 aggactttct caagtgttca gtgactgttt tccaccagaa caagacttgc gttcaggaaa
     3841 tttgtggata attcaccctt ttatgaatca ccaaaataat aatctcaccg acttcgaaga
     3901 agaaaagcta acagagctat cttcagattt aggattacaa gcactattta aatcagtgtc
     3961 tgtaactcag ttttggataa atgcaaagac aagttaccca gaactccatg aaagggcaat
     4021 gaaattttta ttaccctttt caactgttta tttatgtgat gctgcctttt cagctttgac
     4081 tgagtcaaaa caaaaaaatc tgttgggttc tggccctgcc ctaagacttg cagtcacatc
     4141 tttaattcca aggatagaaa aattagtgaa ggagaaagag tagcaatatg cacattgctt
     4201 aacagtgaag tcaataatcc tgtgttaagt tttgtataag tatcctaaaa gataatttcc
     4261 taatgtggat ttgtgttttc agtgattaaa tgttttaata atttttccct ttttgttgag
     4321 gaatttaata attatgattg ttataaataa ttatgtataa ttataatcta gggtagaaaa
     4381 tttagttatt tcattaaatt tggactagtg acaaagactg caggtaatga gaagcccagt
     4441 ttataatgta acagcacaac ctggatgttg aaacagcttg gcctttagaa gcaagtggaa
     4501 catttcagtc ttctagccaa ccagctactt acccctgcaa ggttgtgagt aggtggaaaa
     4561 gatagatctt ttttttgaga tggagttttg ctcttgttgc ccaggctgga gtgcaatggc
     4621 gtgatcttgg ctcactggaa cctctgcctc ctaggttcaa acaattctcc tgcctcagcc
     4681 ttccaagtag ctggggttac aggcatgtgc caccatgccc gtctattgta ttttttttag
     4741 tagagacggg gtttcaccat attggtcagg ctggtctcta tctcctgacc tcaagtgatc
     4801 cacctgcctc ggcctcccaa agtgctggga ttacaagtgt gagccaacgt gcccagctgg
     4861 aaaaagatag atctaagcag cttgggtaac tataaatgga agcagcaggg ggatttgaga
     4921 cccctgcttg gggcctttct ggcccaatat accagggctt agcaaacttt ttaaataaag
     4981 agccagatag taaatatttt cagctttgca ggccatactg tcacaactac tcaattctgc
     5041 agttgcagtg caaaagcagc catagacaat atgcagataa gtgtggctgt ttttaaataa
     5101 aacttattca tgaacactga aa
//
