LOCUS       NM_001012981            7437 bp    mRNA    linear   PRI 09-FEB-2024
DEFINITION  Homo sapiens zinc finger with KRAB and SCAN domains 2 (ZKSCAN2),
            mRNA.
ACCESSION   NM_001012981 XM_292504
VERSION     NM_001012981.5
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 7437)
  AUTHORS   Vaquerizas,J.M., Kummerfeld,S.K., Teichmann,S.A. and Luscombe,N.M.
  TITLE     A census of human transcription factors: function, expression and
            evolution
  JOURNAL   Nat Rev Genet 10 (4), 252-263 (2009)
   PUBMED   19274049
  REMARK    Review article
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC008741.7, DB120548.1, BX648785.1 and BC130007.1.
            
            On Nov 23, 2018 this sequence version replaced NM_001012981.4.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BX648785.1, SRR1803616.11760.1
                                           [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA1965299,
                                           SAMEA1966682 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000328086.12/ ENSP00000331626.7
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-311               AC008741.7         88721-89031
            312-324             DB120548.1         1-13
            325-2716            BX648785.1         2-2393
            2717-3666           BC130007.1         2064-3013
            3667-6617           AC008741.7         106795-109745
            6618-7437           BX648785.1         6290-7109
FEATURES             Location/Qualifiers
     source          1..7437
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="16"
                     /map="16p12.1"
     gene            1..7437
                     /gene="ZKSCAN2"
                     /gene_synonym="ZNF694; ZSCAN31; ZSCAN34"
                     /note="zinc finger with KRAB and SCAN domains 2"
                     /db_xref="GeneID:342357"
                     /db_xref="HGNC:HGNC:25677"
     exon            1..1117
                     /gene="ZKSCAN2"
                     /gene_synonym="ZNF694; ZSCAN31; ZSCAN34"
                     /inference="alignment:Splign:2.1.0"
     CDS             719..3622
                     /gene="ZKSCAN2"
                     /gene_synonym="ZNF694; ZSCAN31; ZSCAN34"
                     /note="zinc finger protein 694; zinc finger and SCAN
                     domain containing 31"
                     /codon_start=1
                     /product="zinc finger protein with KRAB and SCAN domains
                     2"
                     /protein_id="NP_001012999.3"
                     /db_xref="CCDS:CCDS32410.1"
                     /db_xref="GeneID:342357"
                     /db_xref="HGNC:HGNC:25677"
                     /translation="MAVALDSQIDAPLEVEGCLIMKVEKDPEWASEPILEGSDSSETF
                     RKCFRQFCYEDVTGPHEAFSKLWELCCRWLKPEMRSKEQILELLVIEQFLTILPEKIQ
                     AWAQKQCPQSGEEAVALVVHLEKETGRLRQQVSSPVHREKHSPLGAAWEVADFQPEQV
                     ETQPRAVSREEPGSLHSGHQEQLNRKRERRPLPKNARPSPWVPALADEWNTLDQEVTT
                     TRLPAGSQEPVKDVHVARGFSYRKSVHQIPAQRDLYRDFRKENVGNVVSLGSAVSTSN
                     KITRLEQRKEPWTLGLHSSNKRSILRSNYVKEKSVHAIQVPARSAGKTWREQQQWGLE
                     DEKIAGVHWSYEETKTFLAILKESRFYETLQACPRNSQVYGAVAEWLRECGFLRTPEQ
                     CRTKFKSLQKSYRKVRNGHMLEPCAFFEDMDALLNPAARAPSTDKPKEMIPVPRLKRI
                     AISAKEHISLVEEEEAAEDSDDDEIGIEFIRKSEIHGAPVLFQNLSGVHWGYEETKTF
                     LDILRETRFYEALQACHRKSKLYGAVAEQLRECGFLRTPEQCRTKFKSLQKSYRKVKN
                     GHVLESCAFYKEMDALINSRASAPSPSTPEEVPSPSRQERGGIEVEPQEPTGWEPEET
                     SQEAVIEDSCSERMSEEEIVQEPEFQGPPGLLQSPNDFEIGSSIKEDPTQIVYKDMEQ
                     HRALIEKSKRVVSQSTDPSKYRKRECISGRQWENLQGIRQGKPMSQPRDLGKAVVHQR
                     PFVGKRPYRLLKYGESFGRSTRLMCRMTHHKENPYKCGVCGKCFGRSRSLIRHQRIHT
                     GEKPFKCLDCGKSFNDSSNFGAHQRIHTGEKPYRCGECGKCFSQSSSLIIHQRTHTGE
                     KPYQCGECGKSFTNSSHFSAHRRVHTGENPYKCVDCEKSFNNCTRFREHRRIHTGEKP
                     YGCAQCGKRFSKSSVLTKHREVHVREKPLPHPPSLYCPENPHKGKTDEFRKTF"
     exon            1118..1304
                     /gene="ZKSCAN2"
                     /gene_synonym="ZNF694; ZSCAN31; ZSCAN34"
                     /inference="alignment:Splign:2.1.0"
     exon            1305..1396
                     /gene="ZKSCAN2"
                     /gene_synonym="ZNF694; ZSCAN31; ZSCAN34"
                     /inference="alignment:Splign:2.1.0"
     exon            1397..1523
                     /gene="ZKSCAN2"
                     /gene_synonym="ZNF694; ZSCAN31; ZSCAN34"
                     /inference="alignment:Splign:2.1.0"
     exon            1524..2207
                     /gene="ZKSCAN2"
                     /gene_synonym="ZNF694; ZSCAN31; ZSCAN34"
                     /inference="alignment:Splign:2.1.0"
     exon            2208..2699
                     /gene="ZKSCAN2"
                     /gene_synonym="ZNF694; ZSCAN31; ZSCAN34"
                     /inference="alignment:Splign:2.1.0"
     exon            2700..7437
                     /gene="ZKSCAN2"
                     /gene_synonym="ZNF694; ZSCAN31; ZSCAN34"
                     /inference="alignment:Splign:2.1.0"
     regulatory      7394..7399
                     /regulatory_class="polyA_signal_sequence"
                     /gene="ZKSCAN2"
                     /gene_synonym="ZNF694; ZSCAN31; ZSCAN34"
                     /note="hexamer: AATAAA"
     regulatory      7407..7412
                     /regulatory_class="polyA_signal_sequence"
                     /gene="ZKSCAN2"
                     /gene_synonym="ZNF694; ZSCAN31; ZSCAN34"
                     /note="hexamer: AATAAA"
     polyA_site      7416
                     /gene="ZKSCAN2"
                     /gene_synonym="ZNF694; ZSCAN31; ZSCAN34"
                     /note="major polyA site"
     polyA_site      7437
                     /gene="ZKSCAN2"
                     /gene_synonym="ZNF694; ZSCAN31; ZSCAN34"
ORIGIN      
        1 agcgcccccc gcgctctccg cgggccgagt ggacgaggcc gaacgcgagc agcctgccgc
       61 tgccccctgc gagccctggc ttcgccccgc agctcttctc ccttccgggc ggaacagttt
      121 ttgcggcctt tcctcggcgg cagcggtttc ctcaggacgg tcggggccgt cgtgggcccg
      181 aaagagcccg gcgccgctct cggaatccgg cggccccagc ggcacccgcg gcggcctgga
      241 cgtgctgcgg tgacccgagc ccggaacctg gcgccgggcg gggcctgcac atccggcccc
      301 acccactcgg ggactcgcct ctccgcgccc gacccgggag tagcggacac accccctccc
      361 ggcccggctg tccgcctccg cccagccttt cctcagcctg cttcattttt ctcccagtcg
      421 tccagcctcc cggtttccga ctttgcacta agagggatgc actctggaaa accacattgc
      481 gcggtcacat cttgtttgga gaagaggcca ggcttttgca tcttagagta tacgttcacc
      541 ttttcaaggg cctggcatag atttgattaa tcagcctgga ataccctgtt cctgccgacc
      601 tggccgtttt tacctccgta ccttatcaca ctcccaggaa cattaagcag ggagcgcttg
      661 gagtcttctt tgggtcccca ccttgagcta gacgtgaagt tgacccctgg gctgcagcat
      721 ggctgtcgcc ctcgactctc agatcgacgc gcccctggag gttgagggat gcctaataat
      781 gaaggtggaa aaggaccctg agtgggcatc agagcccatt ctggaaggat cggatagctc
      841 tgagaccttc cgcaaatgct tcaggcaatt ctgttatgag gatgtgactg gaccccatga
      901 agctttcagt aaactctggg aactttgctg ccggtggctg aagccagaaa tgcgttccaa
      961 ggagcaaata cttgagctgc tggtgattga gcagtttctc accattttac ccgagaagat
     1021 tcaggcttgg gcacagaagc agtgtccgca aagtggagag gaagcggtgg ccctggtagt
     1081 gcatttggag aaagagactg gaagactaag acagcaggtc agcagtcccg tgcaccggga
     1141 gaagcactcc ccacttggag cagcgtggga ggtggcagac ttccagccag agcaggtgga
     1201 gacccaaccc agggcggtgt ctcgggagga acctggaagc ctccactcag gacaccagga
     1261 acagctgaac cgaaagcgag aacgtcggcc cttacccaag aatgctcggc cttctccctg
     1321 ggttcctgcc cttgctgatg aatggaatac cctagatcag gaagtgacaa ccacacggct
     1381 tcctgctggg tcccaggaac cagtgaaaga tgtccacgtg gccagaggct tttcctacag
     1441 aaagagtgtg catcagattc ctgcccaaag ggacctctac cgggatttca ggaaggagaa
     1501 tgttgggaac gtggtctccc tgggaagtgc agtgtctaca tctaacaaga taacccggtt
     1561 ggaacagaga aaggagccat ggactctagg tctgcattcc tctaacaaga gaagtatcct
     1621 acgaagcaac tacgtcaagg aaaagtcagt tcatgctatt caggtccctg caaggagtgc
     1681 aggaaaaaca tggagagagc agcagcagtg gggtttagaa gatgaaaaga tagcaggtgt
     1741 gcattggagc tatgaggaaa caaagacttt cctggcaatt ctcaaagagt ctcgctttta
     1801 tgaaacactt caggcctgtc cccgaaatag ccaagtgtat ggtgctgtgg ctgaatggtt
     1861 gcgagaatgt ggcttcctta gaaccccaga acagtgtcga accaagttca aaagtctcca
     1921 gaaaagctat cgaaaggtga gaaatggcca catgctagaa ccctgcgcct tctttgagga
     1981 catggatgct ttgttgaacc ctgcagcccg tgctccgtcc actgataaac caaaggagat
     2041 gatacctgtc cccagactga agagaattgc catcagtgct aaggaacaca tcagcttggt
     2101 ggaggaggag gaagctgcag aagattctga tgatgatgaa ataggcatcg aatttatccg
     2161 caagtctgaa atccatggtg cccctgtctt gtttcagaat ctcagtggcg tgcactgggg
     2221 ctatgaagaa accaagactt ttcttgatat cctccgtgag actcggtttt atgaagcgct
     2281 tcaagcctgt catcggaaga gcaaattgta tggggctgta gctgaacagc ttcgagagtg
     2341 cggcttcctc cggacaccag aacagtgccg aaccaagttc aaaagccttc agaagagtta
     2401 ccgcaaggtg aaaaatggcc acgtgctaga gtcctgcgcg ttctacaagg agatggatgc
     2461 cctgattaac tctcgggcat ctgctccttc ccccagcacc ccagaggaag tcccatcacc
     2521 ttcaaggcaa gaaagagggg gtattgaggt tgaaccccag gaacctacag gctgggaacc
     2581 tgaagagacc tcacaggagg cagtaataga agactcttgc agtgagagaa tgagcgagga
     2641 ggaaattgtg caagagccag agttccaggg acctccaggt ctactgcaga gcccaaatga
     2701 ttttgaaatc ggaagtagca tcaaggagga tccaacacag atagtatata aggacatgga
     2761 acagcatagg gcattaatag aaaagtctaa aagagttgtt tcccagagta ccgaccccag
     2821 caaatatcgc aaaagggaat gcatctcagg aagacaatgg gaaaatcttc aaggaattag
     2881 acagggaaag ccgatgtctc agcctagaga tttagggaaa gccgttgtgc atcagaggcc
     2941 ttttgtgggg aagagaccct acagacttct caaatatgga gaaagctttg gaaggagcac
     3001 tcgtctgatg tgccggatga cccaccacaa ggagaatcct tacaagtgtg gtgtctgtgg
     3061 gaagtgcttt ggtagaagca ggagcctgat cagacaccaa agaatccaca caggcgaaaa
     3121 accttttaaa tgtcttgact gtggaaaaag ctttaatgac tcctcaaatt ttggtgccca
     3181 ccagagaatc cacacaggag agaaacccta cagatgcgga gagtgtggaa aatgctttag
     3241 tcagagctct agtcttatta tacatcagag aacgcacacc ggtgagaagc cctatcagtg
     3301 tggagagtgt gggaaaagtt tcaccaacag ttctcatttc agcgcccacc ggagagttca
     3361 cactggggag aatccctaca aatgtgtgga ctgtgaaaaa agtttcaata actgtacgag
     3421 atttcgagaa catcggagaa tacacactgg agagaagccc tatggatgtg cccagtgtgg
     3481 caaacgtttc agtaagagtt ctgttcttac caaacatcgg gaagttcatg tgagagaaaa
     3541 gcctctgcca caccctccat ctctgtattg ccctgagaac ccacataagg gaaagactga
     3601 tgaatttagg aaaacttttt gatgatgatc ttctcttcct aaatgccccc ttagccattt
     3661 taccctaatc tcattcttgg aagcaatctt ttcttagcta tgaagtgtaa tttccaagat
     3721 aaacttgaga atataaataa actaaacact ttcatcctgt tctcacctct gcctctaact
     3781 tcatcagtct gttcctcctc ttctgtgtgt ctcagcttct cctttaagaa tgtggcgaag
     3841 atacattgtc cgagttcaga atgaaatacc cttcagtaca ttgaggccac tgcaactgga
     3901 ttgctaagtt cggcaacatt caagatcttc catatgggtg agagttgtct tcaaggatat
     3961 aaaaaatgcc aaaagttttt ttgttgttat tacctactcc gtgagatcct ggatgaaact
     4021 tgataacaga ttttcacatt tagatagaac tttgaggagt ctgatcggaa ctacatcaaa
     4081 tccatcttgg ttttgaagag atccacaaaa gaagagtgaa gattttatag ctttcctcag
     4141 aagtctgtta cagtgtacct tttttttttt ttttgtcaag aagttgatcc aaatagctag
     4201 ggcagaatcc ctgtattgtc actgaaatcc tgttactaat gccttgccct ccatggaggt
     4261 gagaagcaat tgatcacccc tcatcctttt ctgtacccga agacttaaat cccctggctg
     4321 ctgcttctcc agcctataag taatcccagg tcctcctact gtttctcata gccctgcact
     4381 tgcctctcag ttgctctggg tgctcctgcc ggcctcttcc gaactaccat gccctcctca
     4441 gatagaatag gaggcctgct cgtggtgtgt ctcactaaag caaagtagga tttcagatgc
     4501 gttctagttc tatcctctaa cttctctggc tcttatctag aacatgactg gcatgttggc
     4561 atatttcgta cctcccaccc ctgcactgca gtataatatt ataatagtgt ttctaaaact
     4621 ttaaggggat agggaagagg taatagacac ctgaagcatt tctaagacca gttggactcc
     4681 tttggcctgc tgtcgatcag atagccacct cagcttagac cagcgctctc aggtctggct
     4741 gttaaatctc ccagtctctt ttcctgaggc ttctagtccc tgttcaccgc atcagaaacc
     4801 taactgtagt gtgccaagta acttaacaca actctagagc tcactgggtg aaaagtggga
     4861 acatttataa aaacttcaat ccagaaatcc agaacaccgt ttttgttttc ctcatttact
     4921 tgttttgtct gaaaaatctc tttgagaacc cccggcagta acccagtaaa cactgaagga
     4981 aaagttctga tgggggatgg ttaattgact tttgaagtta cagatgaaac ccagagattt
     5041 gattttccat ggccagttgc ttcaggatgg agtcagtggc gtttattccc ttagtatgta
     5101 ggtgacccag ggtggctttg ctttggcaag ggagaagtca caagtttaat gggaagggaa
     5161 ccggagttag ggctgtttgt gggtgattat tttgctcttc tctctccctt tctttgtcaa
     5221 atgctcttat ttgaagccat ctggaaatga tatttttcct tttggtatgt ttcaatcttt
     5281 tgaaacttgt tcagcaaagt acctaggagg gtaggcactg tagaaagaaa tctaatttat
     5341 ggtgccagaa tagggtgtgg cctgttggaa ggcaggtgac tcaggtagac attgataaat
     5401 gtttctgatt tacatttgtt ggaaatatta tgactgttca catctcaata ggttgatttt
     5461 tctgtgttgt ccaagttata gatttctaat gctaagtaca gttccatgtt ggtagtgtgc
     5521 gtagcacagt aagatgtttg tggtgccagt gggcttgtgt ttatattgtg tagatgttct
     5581 ggaattccag ctctagagaa gatgtaaatt aatagaaatc accacttaat aatatgtaca
     5641 caggattgat attatgtgga agcatgattc aggaaagtag atgacttatt cataaatatg
     5701 aagcactgtt acatgtaagg ccatgttcta gccacagtga atgatagaaa aaggaaggaa
     5761 ggggcatggt gcctgggctc aaggaactca cagtttgata gaggaagcat cacagcaaaa
     5821 gttggggcca cttacaccat ggcagttaca gaaggccagg agctcagtca tgagaacatc
     5881 accttcccct gcagaagagt tgcgctaagt tgcccagaat catattctgt accttcatct
     5941 ctcaaccttc cccagtggca ggaaagggtc aagcaagacc cattccctct ctagtgggac
     6001 aaactgattc tgtttaactc tcatatgcct gggagcaagc tgaggtggaa tttgggttcc
     6061 cctatctcta ctcctaattg taaatgggct gtctagacat gtgttacatt aatttgatga
     6121 actttgttct gaagaaatgg aaggtctccc ccccatttta gaccaacact acctgtctcc
     6181 ctgcatttta tttgttttca cctggtacat gtaagtcaaa atgaataatc atgttctgac
     6241 caatgtgtct tttagatcac ataacattgc ctttatgaag attcatagaa aaaggttttt
     6301 ttatctagat ctcagtgcca aggaaagctc tgatcctaag cgcagtatgt gtacacacac
     6361 acgtctacat gtgtgtgtag atctgtatgt atgtattaca aacactgtga tttttgtaac
     6421 ttaagctgct ttttctctct ttgttctggc tgctggaaag ttcaacaaaa cttacagccc
     6481 acctcaacca actaccccaa cctatattta tttaatttca tcttatttcc ttgtaaattg
     6541 tgtcaaatcc tgtttttgaa aagcagcata gactgacaac ttttcactat catcttatcg
     6601 aaggcatttt ggaaactggg gtcgtatgtc ccacctaggc ttgctttgtt actgccacaa
     6661 atacctccag ttcttaccag tgatgttatt atgcattcaa cctaattcat tcatctggaa
     6721 agaaacagtt ttttaaaaag ggaaacctca cacgtaaatg gctcagggca gcctggcctt
     6781 ggtggaatga gcatgagact ggaagctgaa agaagcaagt tttaatcttg tcactaaatg
     6841 agtgttgttt gacacatcat agcctctctg ggcctcggct cctcatctga agagaagttg
     6901 aacttaactg ctaagttgct ctggctctaa tgtttcatga ggctgtggag cgtgatatag
     6961 atgcggaaga ggttagaaga ccaggctgcc ggcccagctg tcctgtgcct gccacatctg
     7021 gccataccaa atccatcgca tgcttcagga aagggagggg atgctgtgac agcaaactca
     7081 gcccaggagc ttgttgggga aggagaaagg gcaagtccct cgtggtccac agcaggcacc
     7141 ccccaagcac ctcgataacc agtggcaggt aggctgaagt gaaggaagcc tctgtcagga
     7201 ggtctggcgc ccagtgacag acaagacagc tgtgagggag ctggggcagc cctggctaaa
     7261 ggaatgtctg agtaacttgt gaaactggaa gcctctgcct ctgaatgcat tccaagacct
     7321 ggtgcaaatg gatgtccatt cattgttttg tatcagtgtt cacttagatg tcttcttgaa
     7381 aacttgtttg tggaataaat gtctaaaata aatggctccc actggtttct gccataa
//
