LOCUS       XM_047431173            8484 bp    mRNA    linear   PRI 25-AUG-2024
DEFINITION  PREDICTED: Homo sapiens zinc finger FYVE-type containing 26
            (ZFYVE26), transcript variant X1, mRNA.
ACCESSION   XM_047431173
VERSION     XM_047431173.1
DBLINK      BioProject: PRJNA168
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_000014.9) annotated using gene prediction method: Gnomon,
            supported by mRNA and EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_000001405.40-RS_2024_08
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           RefSeqFE; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 08/23/2024
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8484
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="14"
     gene            1..8484
                     /gene="ZFYVE26"
                     /gene_synonym="FYVE-CENT; SPG15"
                     /note="zinc finger FYVE-type containing 26; Derived by
                     automated computational analysis using gene prediction
                     method: Gnomon. Supporting evidence includes similarity
                     to: 1 mRNA, 19 ESTs, 422 long SRA reads, and 100% coverage
                     of the annotated genomic feature by RNAseq alignments,
                     including 41 samples with support for all annotated
                     introns"
                     /db_xref="GeneID:23503"
                     /db_xref="HGNC:HGNC:20761"
                     /db_xref="MIM:612012"
     CDS             141..7634
                     /gene="ZFYVE26"
                     /gene_synonym="FYVE-CENT; SPG15"
                     /codon_start=1
                     /product="zinc finger FYVE domain-containing protein 26
                     isoform X1"
                     /protein_id="XP_047287129.1"
                     /db_xref="GeneID:23503"
                     /db_xref="HGNC:HGNC:20761"
                     /db_xref="MIM:612012"
                     /translation="MNHPFGKEEAASQKQLFGFFCECLRRGEWELAQACVPQLQEGQG
                     DIPKRVEDILQALVVCPNLLRCGQDINPQRVAWVWLLVLEKWLAREKKLLPVVFRRKL
                     EFLLLSEDLQGDIPENILEELYETLTQGAVGHVPDGNPRRESWTPRLSSEAVSVLWDL
                     LRQSPQPAQALLELLLEEDDGTGLCHWPLQNALVDLIRKALRALQGPDSVPPGVVDAI
                     YGALRTLRCPAEPLGVELHLLCEELLEACRTEGSPLREERLLSCLLHKASRGLLSLYG
                     HTYAEKVTEKPPRATASGKVSPDHLDPERAMLALFSNPNPAEAWKVAYFYCLSNNKHF
                     LEQILVTALTLLKEEDFPNLGCLLDREFRPLSCLLVLLGWTHCQSLESAKRLLQTLHR
                     TQGPGCDELLRDACDGLWAHLEVLEWCIQQSSNPIPKRDLLYHLHGGDSHSVLYTLHH
                     LTNLPALREEDVLKLLQKVPAKDPQQEPDAVDAPVPEHLSQCQNLTLYQGFCAMKYAI
                     YALCVNSHQHSQCQDCKDSLSEDLASATEPANDSLSSPGAANLFSTYLARCQQYLCSI
                     PDSLCLELLENIFSLLLITSADLHPEPHLPEDYAEDDDIEGKSPSGLRSPSESPQHIA
                     HPERKSERGSLGVPKTLAYTMPSHVKAEPKDSYPGPHRHSFLDLKHFTSGISGFLADE
                     FAIGAFLRLLQEQLDEISSRSPPEKPKQESQSCSGSRDGLQSRLHRLSKVVSEAQWRH
                     KVVTSNHRSEEQPSRRYQPATRHPSLRRGRRTRRSQADGRDRGSNPSLESTSSELSTS
                     TSEGSLSAMSGRNELHSRLHPHPQSSLIPMMFSPPESLLASCILRGNFAEAHQVLFTF
                     NLKSSPSSGELMFMERYQEVIQELAQVEHKIENQNSDAGSSTIRRTGSGRSTLQAIGS
                     AAAAGMVFYSISDVTDKLLNTSGDPIPMLQEDFWISTALVEPTAPLREVLEDLSPPAM
                     AAFDLACSQCQLWKTCKQLLETAERRLNSSLERRGRRIDHVLLNADGIRGFPVVLQQI
                     SKSLNYLLMSASQTKSESVEEKGGGPPRCSITELLQMCWPSLSEDCVASHTTLSQQLD
                     QVLQSLREALELPEPRTPPLSSLVEQAAQKAPEAEAHPVQIQTQLLQKNLGKQTPSGS
                     RQMDYLGTFFSYCSTLAAVLLQSLSSEPDHVEVKVGNPFVLLQQSSSQLVSHLLFERQ
                     VPPERLAALLAQENLSLSVPQVIVSCCCEPLALCSSRQSQQTSSLLTRLGTLAQLHAS
                     HCLDDLPLSTPSSPRTTENPTLERKPYSSPRDSSLPALTSSALAFLKSRSKLLATVAC
                     LGASPRLKVSKPSLSWKELRGRREVPLAAEQVARECERLLEQFPLFEAFLLAAWEPLR
                     GSLQQGQSLAVNLCGWASLSTVLLGLHSPIALDVLSEAFEESLVARDWSRALQLTEVY
                     GRDVDDLSSIKDAVLSCAVACDKEGWQYLFPVKDASLRSRLALQFVDRWPLESCLEIL
                     AYCISDTAVQEGLKCELQRKLAELQVYQKILGLQSPPVWCDWQTLRSCCVEDPSTVMN
                     MILEAQEYELCEEWGCLYPIPREHLISLHQKHLLHLLERRDHDKALQLLRRIPDPTMC
                     LEVTEQSLDQHTSLATSHFLANYLTTHFYGQLTAVRHREIQALYVGSKILLTLPEQHR
                     ASYSHLSSNPLFMLEQLLMNMKVDWATVAVQTLQQLLVGQEIGFTMDEVDSLLSRYAE
                     KALDFPYPQREKRSDSVIHLQEIVHQAADPETLPRSPSAEFSPAAPPGISSIHSPSLR
                     ERSFPPTQPSQEFVPPATPPARHQWVPDETESICMVCCREHFTMFNRRHHCRRCGRLV
                     CSSCSTKKMVVEGCRENPARVCDQCYSYCNKDVPEEPSEKPEALDSSKNESPPYSFVV
                     RVPKADEVEWILDLKEEENELVRSEFYYEQAPSASLCIAILNLHRDSIACGHQLIEHC
                     CRLSKGLTNPEVDAGLLTDIMKQLLFSAKMMFVKAGQSQDLALCDSYISKVDVLNILV
                     AAAYRHVPSLDQILQPAAVTRLRNQLLEAEYYQLGVEVSTKTGLDTTGAWHAWGMACL
                     KAGNLTAAREKFSRCLKPPFDLNQLNHGSRLVQDVVEYLESTVRPFVSLQDDDYFATL
                     RELEATLRTQSLSLAVIPEGKIMNNTYYQECLFYLHNYSTNLAIISFYVRHSCLREAL
                     LHLLNKESPPEVFIEGIFQPSYKSGKLHTLENLLESIDPTLESWGKYLIAACQHLQKK
                     NYYHILYELQQFMKDQVRAAMTCIRFFSHKAKSYTELGEKLSWLLKAKDHLKIYLQET
                     SRSSGRKKTTFFRKKMTAADVSRHMNTLQLQMEVTRFLHRCESAGTSQITTLPLPTLF
                     GNNHMKMDVACKVMLGGKNVEDGFGIAFRVLQDFQLDAAMTYCRAARQLVEKEKYSEI
                     QQLLKCVSESGMAAKSDGDTILLNCLEAFKRIPPQELEGLIQAIHNDDNKIVPILAAL
                     RDRVHTEERGRSPSTLC"
     polyA_site      8484
                     /gene="ZFYVE26"
                     /gene_synonym="FYVE-CENT; SPG15"
                     /experiment="COORDINATES: polyA evidence [ECO:0006239]"
ORIGIN      
        1 gactcggctc aaacatggct gcgctgagag ctctattgct ttgggcgccg ggagcaggag
       61 gtactccgcg aatgagaaca ttgagaatgt gttcggcata actcatttct ttgtatctcc
      121 ctgcactctg tgctgggaaa atgaatcatc catttggaaa agaggaagct gcttcgcaga
      181 agcagctttt tggatttttc tgcgaatgcc tgcggagggg agaatgggag ctggcacagg
      241 catgtgtacc tcagctacag gagggacaag gggatatccc aaagagggta gaagacatac
      301 ttcaggcatt ggtggtgtgt ccaaatctgc tgagatgtgg gcaggacatc aaccctcaaa
      361 gagtagcctg ggtctggctt cttgtactgg agaaatggtt ggcccgggaa aagaagttac
      421 tcccagttgt tttccggaga aagcttgagt ttcttttatt gtcagaagac ctccaaggtg
      481 acattccaga gaacatcctc gaggagctgt atgagacctt aacacagggt gcagtaggcc
      541 acgtgcctga cggaaatcca aggagggaga gctggactcc tcgtctcagc tccgaagctg
      601 tctctgtgct ctgggatctc ctgaggcagt ctccccagcc agcacaggcc ctgctggagc
      661 tcctgcttga ggaggatgac ggtactggcc tctgtcactg gcctctgcag aatgcactgg
      721 tggacctcat tcgaaaggca ttgcgggctt tgcagggccc tgattcggtg ccccctgggg
      781 tagtcgatgc catctatgga gccctgcgga ctctgcgttg ccccgcagaa ccacttgggg
      841 ttgagttgca tctcctgtgt gaggaactac tagaggcctg caggaccgag gggagtcccc
      901 tgcgggagga gcggctgctc agctgcctgc tgcacaaggc cagccggggc ctgctgtccc
      961 tgtatggcca tacctatgca gagaaggtca cagaaaagcc accgagggct acagcctcgg
     1021 gaaaagtctc accggatcat ctagatcctg agcgggcaat gctagccctg ttctccaatc
     1081 ccaacccagc cgaggcttgg aaagtggcct atttctactg cctgagcaac aacaaacact
     1141 tcctcgagca gattctggta acagcactaa cattgttgaa agaagaagac ttcccaaatc
     1201 ttggctgcct acttgataga gaattcaggc ccctcagttg cctgcttgta ctcctgggct
     1261 ggacacactg ccagagccta gagtcagcca agaggctgct ccagaccctg cacaggaccc
     1321 agggcccagg ctgtgatgag ctcctcaggg atgcctgtga tgggttgtgg gctcacctgg
     1381 aggtcctgga gtggtgcata cagcagagca gcaaccccat accaaagaga gatctgttgt
     1441 atcatttaca cggtggagac agccactcag tgctctacac tctccatcac cttacaaacc
     1501 ttccagccct cagggaggaa gatgttctca agctcttaca gaaagtgcca gccaaggacc
     1561 cccagcaaga gcctgatgca gttgatgctc cagtccctga gcacctgagc cagtgtcaga
     1621 acctgacact ctaccagggc ttctgtgcca tgaagtatgc catctatgcc ctctgtgtaa
     1681 actcacacca gcactcccag tgccaggact gcaaagacag cctctctgag gacctggcct
     1741 cagctacaga gccagcgaat gactctctct cctccccagg tgctgcaaat ctcttctcaa
     1801 cttacctggc caggtgtcaa cagtatctgt gcagtattcc tgactctctg tgcctggagc
     1861 ttctggaaaa catcttctca ttgcttctca tcacctctgc tgatcttcac ccagagcctc
     1921 acttgcctga ggactatgct gaggatgatg acattgaggg gaagagcccc tcaggtttga
     1981 ggtccccatc agagagccct cagcacatag cacatcctga aaggaagtca gaacggggtt
     2041 ccctgggagt cccaaagacc cttgcttata caatgccaag ccatgtgaag gcagagccaa
     2101 aagacagtta cccagggcct cataggcaca gctttttgga cttaaaacac tttactagtg
     2161 gtatcagtgg atttctggct gatgaatttg caataggggc cttcctcagg cttctccaag
     2221 agcaactgga tgagatcagt agccgcagcc ctcctgagaa gccaaagcaa gaaagtcaga
     2281 gctgctcagg aagcagagat ggactgcaga gccgcctgca tcgactttcc aaggttgtct
     2341 ctgaggccca gtggagacac aaggtggtga caagcaacca tcgttcagag gagcaacctt
     2401 cccgaagata ccagcctgcc acacgtcacc ccagtctccg ccggggtcgt cggacaagaa
     2461 ggagccaggc agatggccga gacagaggtt caaacccatc cctggaaagt acaagtagtg
     2521 agctgagcac aagtacgtca gagggaagtc tgagtgccat gtctggccgg aatgagctgc
     2581 acagtagatt gcacccccat cctcaaagtt cactcatccc catgatgttc tccccacctg
     2641 agtcactgct ggcatcctgc atccttcgcg ggaacttcgc agaagcccat caggtgctgt
     2701 tcacgttcaa cctgaagtcc tcacccagtt caggggaact gatgttcatg gagcgctacc
     2761 aggaagtgat ccaagaactg gcccaagtag agcacaagat tgaaaaccag aactcagatg
     2821 cgggtagcag caccattcgg agaactggca gtggccgctc aactctacag gccattggca
     2881 gcgctgcagc agcaggaatg gtgttttact ctatctctga cgtgactgac aagctgctca
     2941 acacctctgg agaccccatc cccatgctcc aggaggactt ttggataagc acggctctag
     3001 tggagcccac tgctcccctg agagaggttc tggaagacct cagtccccct gccatggctg
     3061 catttgacct agcttgctct cagtgccagc tctggaaaac ctgcaagcag cttttggaga
     3121 cagccgaacg gcgtttgaat agtagccttg aaaggcgggg tcgacggata gaccacgtac
     3181 tcctaaatgc tgatggcatt cgaggttttc cagttgttct tcagcaaatc agtaagagtc
     3241 tcaattatct gcttatgtca gccagtcaaa ccaaatcaga gagtgtggaa gaaaagggag
     3301 gaggccctcc acggtgcagc atcactgaac tgcttcagat gtgctggccc agcctaagcg
     3361 aggactgtgt tgccagccac accaccctct cccagcagct agatcaggtc cttcagtcac
     3421 tgagagaggc actagagctg ccagagccca ggactcctcc actgtcttcc ctggtggagc
     3481 aggcagccca gaaagctcca gaggcagagg cccaccctgt gcagatccag actcagctcc
     3541 tccagaagaa cctgggcaaa cagaccccat caggcagcag gcagatggac tacttgggca
     3601 ccttcttcag ttactgcagc acccttgctg cagttctcct tcaaagtttg agctctgagc
     3661 ctgatcatgt ggaggtcaag gtaggaaatc cctttgttct gctgcaacag agctcttccc
     3721 aactggtgtc acatctcctg tttgagagac aagttccccc agagagactg gcagcccttc
     3781 tggcccaaga gaatctcagc ctaagtgtgc cacaggtcat cgtcagctgc tgctgtgagc
     3841 cccttgctct ttgctcatcc cggcaaagcc agcagacctc ctccctcctg actcgtctgg
     3901 gtactctggc ccagctacac gcctctcact gcctggatga cctcccactt tctacaccga
     3961 gctccccgag gacaactgag aaccctacat tggaaagaaa gccctactcc tccccaaggg
     4021 actcatcact cccagccctc acctcctctg ccttggcctt tcttaagtca cgctcaaagc
     4081 tcctagctac ggtggcctgc ctgggggctt ccccgaggtt aaaggtcagc aaacccagct
     4141 tgtcatggaa ggaacttcgt ggccgcaggg aggtgcctct ggctgcagag caggtagccc
     4201 gggagtgtga gcgccttctg gaacaattcc ctctgtttga ggccttcctc ctggctgcct
     4261 gggagcccct gcgagggtct ttgcagcagg ggcagagtct ggcagtgaat ctctgtggtt
     4321 gggccagtct ttctaccgtt ctcctgggcc tacattctcc cattgcccta gatgtactga
     4381 gtgaggcttt tgaggaatcc ttggtggcca gagattggtc ccgggccctt cagctcactg
     4441 aagtgtacgg gcgagatgtg gacgatttga gcagcataaa ggatgcagtc ctgagctgtg
     4501 ctgtggcatg tgacaaagaa ggttggcaat acctgtttcc cgtgaaggat gcatctctga
     4561 gaagtcggct ggccctacag tttgtggaca ggtggcccct ggagtcatgc ctggagattc
     4621 tggcctactg catttcagac acggctgtcc aagaaggact aaagtgtgag ctacagagga
     4681 agctggcgga gctgcaggtg tatcagaaga ttctgggttt gcagtctccc ccagtgtggt
     4741 gtgactggca gaccttgagg agctgttgtg ttgaggaccc atcaactgtc atgaacatga
     4801 ttctagaagc acaggagtat gaactgtgtg aagagtgggg ctgcctgtac cccattccaa
     4861 gagaacattt aatcagcctt catcaaaagc atcttctcca ccttctagaa agaagagatc
     4921 atgacaaggc tctgcaactc ctgcgaagaa tccctgaccc caccatgtgc cttgaagtga
     4981 cagagcaatc cctcgaccag cacactagct tggccacttc tcacttcttg gccaactacc
     5041 tcaccaccca cttctatgga caactgactg ctgtccgaca ccgtgaaatc caggcgctgt
     5101 atgtgggatc caagattctg ctgaccctgc ctgagcagca ccgggccagc tattcccact
     5161 tgtcctctaa ccccctgttc atgctggagc agctgcttat gaacatgaag gtggattggg
     5221 ccactgtggc tgtgcagact ctccagcagc tgctggttgg acaggagatt ggcttcacta
     5281 tggacgaggt ggactcactg ctttccagat acgcagagaa agccctggac tttccatacc
     5341 ctcagaggga gaaacgatca gattctgtga ttcacctcca agaaattgtc caccaggctg
     5401 cagatcccga gaccctccct agatcaccat cagcagagtt ctctcctgct gctcctcctg
     5461 gtatctccag tatacattcc cctagtctaa gggaaaggag tttcccacca acccagccct
     5521 cacaggaatt tgtgccccca gcgacacccc ctgccaggca ccagtgggta ccggatgaga
     5581 ctgagagtat ctgcatggtc tgctgcaggg agcacttcac catgtttaac aggcgtcatc
     5641 attgtcgccg ctgtggccgg ctagtgtgca gctcctgctc cactaagaaa atggtggttg
     5701 aaggctgcag agagaaccct gctcgtgtgt gtgatcagtg ctatagttac tgcaacaaag
     5761 atgtaccaga ggagccttca gaaaaaccag aagctctaga cagctccaag aatgaaagcc
     5821 ctccatactc gtttgtggtg agagtcccca aagcagatga ggtggaatgg attttggatc
     5881 tcaaagagga ggaaaatgag ctggtgcgga gtgaatttta ctatgagcag gcccccagcg
     5941 cctccttgtg cattgccatc ctgaatctgc accgggacag cattgcctgt ggtcaccagc
     6001 tgattgagca ctgctgcagg ctctccaagg gcctcaccaa cccagaggtg gatgccgggc
     6061 tgctcacgga catcatgaag cagctgctgt tcagcgccaa gatgatgttc gtcaaagccg
     6121 gccagagcca agacttggct ctttgtgaca gctacatcag caaggtagat gtgctgaata
     6181 ttttagttgc tgctgcctat cgccacgtgc catctttgga tcagatcttg cagccagctg
     6241 cagtaaccag gctaaggaac cagcttttgg aagccgagta ctaccaactg ggcgttgagg
     6301 tctccacaaa gactgggctt gataccaccg gggcgtggca tgcttggggc atggcctgcc
     6361 tcaaagccgg gaacctcact gctgcacggg agaagttcag tcgctgtctg aagcccccat
     6421 ttgacctcaa tcagctgaat catggctcaa ggctggtgca ggatgtggtt gagtacctag
     6481 agtccacagt gaggcccttt gtatccttgc aagatgacga ttactttgcc accctgaggg
     6541 aactggaagc tacccttcgg acgcagagcc tttctctggc agtgattcct gaagggaaaa
     6601 tcatgaacaa cacctactac caggaatgcc tcttctacct gcacaactat agcaccaacc
     6661 tggccatcat cagcttctac gtgaggcaca gctgcctgcg ggaagctctt ctgcaccttc
     6721 tcaacaagga gagtcctcca gaagttttta tagaaggcat tttccaacca agctataaaa
     6781 gtgggaagct acacactttg gagaacttgc tagaatccat tgatccaacc ttggagagct
     6841 ggggaaagta cttgattgct gcctgccaac atttacagaa gaagaactac taccacattc
     6901 tgtatgagct gcagcagttt atgaaggacc aagttcgggc cgccatgacc tgtattcggt
     6961 tcttcagtca caaagcaaag tcatatacag aactgggaga gaagctctca tggctactta
     7021 aggccaagga ccacctgaag atctacctcc aagaaacatc ccgcagctct ggaaggaaga
     7081 aaaccacatt cttcagaaag aagatgactg cagctgatgt gtcaaggcac atgaacacac
     7141 ttcagctgca gatggaagtg accaggttct tgcatcggtg cgaaagtgct gggacctctc
     7201 aaatcaccac tttgcctctg ccaaccctgt ttggaaataa ccacatgaaa atggatgttg
     7261 cctgcaaggt catgctggga gggaaaaatg tagaagatgg ttttggaatt gctttccgtg
     7321 ttctgcagga cttccagctg gatgctgcca tgacctactg cagagctgcc cgccagttgg
     7381 tggagaaaga gaagtacagt gagatccagc aactgctcaa atgtgtcagt gagtcaggca
     7441 tggcagccaa aagtgacggg gacaccatcc tcctcaactg cctggaagcg ttcaagagaa
     7501 ttccgcccca ggagctggag ggcctgatcc aggcaataca caatgatgac aacaagatag
     7561 tgccaatctt ggcagcattg agggacagag ttcacaccga agagagagga cgttccccta
     7621 gcactttgtg ctaattggta tttaaaaatt catgaatcaa gtgagccaaa agcttaaaga
     7681 aggagaaaaa cgatccagat ctccatggca taaccaacag cgacagtctt ctttaaaagc
     7741 tttcagaaag ctgcaaagtt ttcatggaaa agcggcacac gagtataaaa taaagccaga
     7801 aaagcaactc ttcccaacac ataagtttgt actgtaagtt tccttaacaa agcaacggca
     7861 ttctgtttgc aggcccaacc caaacctgga ttgcatcatc aggcacaaac tcagcttctc
     7921 aggatgaaca gcccagcgag tccggcacct cccatgcaca caggtggtgg agagaaccgc
     7981 attgccttca cacacctgaa gtacttgcca ctcaggggct ccaggccctc agccagggcg
     8041 cagtgcaggc tggtctgcgc cccctcccgt gccgtcttga caaaggggga gaagagccgc
     8101 cagagcaggc agagcaggga ggagtgccgg accagctcag agcggacgac gcctgggtgc
     8161 actgcgtagg tggtgacccc ggtgcctggg acaaagaggg cacaattaga tcagggacac
     8221 actctgagcc caggaaaaca gcttatctcc tgcagcaaaa tacacaagtg agaaggaggg
     8281 actcaggaaa cataacccca ggattcagca ggtaccactc ctggccaggc ggaatttgaa
     8341 caggaatgaa ttgatctttc agaaagatct atagccttct cagccttcta tgttccaaaa
     8401 ggagtgcctg gttcgaggtc cttctatttc aatgtcgttt ttatactgtg gctttagtac
     8461 tactaataaa catgacaaca tgta
//
