LOCUS       NM_015174               4766 bp    mRNA    linear   PRI 06-JUN-2024
DEFINITION  Homo sapiens zinc finger RNA binding protein 2 (ZFR2), transcript
            variant 1, mRNA.
ACCESSION   NM_015174 XM_001130130 XM_001130674
VERSION     NM_015174.2
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 4766)
  AUTHORS   Gaudet,P., Livstone,M.S., Lewis,S.E. and Thomas,P.D.
  TITLE     Phylogenetic-based propagation of functional annotations within the
            Gene Ontology consortium
  JOURNAL   Brief Bioinform 12 (5), 449-462 (2011)
   PUBMED   21873635
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC093078.3, DA333602.1, AC004598.1, AB029009.1 and AC005777.1.
            
            On Nov 22, 2018 this sequence version replaced NM_015174.1.
            
            Transcript Variant: This variant (1) is a longer transcript and
            encodes the full-length protein (isoform 1).
            
            ##Evidence-Data-START##
            RNAseq introns :: mixed sample support SAMEA1968540, SAMEA1968968
                              [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000262961.9/ ENSP00000262961.3
            RefSeq Select criteria :: based on conservation
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-9                 AC093078.3         34755-34763         c
            10-400              DA333602.1         1-391
            401-619             AC004598.1         26575-26793         c
            620-2664            AB029009.1         489-2533
            2665-4766           AC005777.1         40713-42814         c
FEATURES             Location/Qualifiers
     source          1..4766
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="19"
                     /map="19p13.3"
     gene            1..4766
                     /gene="ZFR2"
                     /gene_synonym="KIAA1086"
                     /note="zinc finger RNA binding protein 2"
                     /db_xref="GeneID:23217"
                     /db_xref="HGNC:HGNC:29189"
                     /db_xref="MIM:619284"
     exon            1..74
                     /gene="ZFR2"
                     /gene_synonym="KIAA1086"
                     /inference="alignment:Splign:2.1.0"
     CDS             22..2841
                     /gene="ZFR2"
                     /gene_synonym="KIAA1086"
                     /note="isoform 1 is encoded by transcript variant 1"
                     /codon_start=1
                     /product="zinc finger RNA-binding protein 2 isoform 1"
                     /protein_id="NP_055989.1"
                     /db_xref="CCDS:CCDS45921.1"
                     /db_xref="GeneID:23217"
                     /db_xref="HGNC:HGNC:29189"
                     /db_xref="MIM:619284"
                     /translation="MATSQYFDFAQGGGPQYSAQPPTLPLPTVGASYTAQPTPGMDPA
                     VNPAFPPAAPAGYGGYQPHSGQDFAYGSRPQEPVPTATTMATYQDSYSYGQSAAARSY
                     EDRPYFQSAALQSGRMTAADSGQPGTQEACGQPSPHGSHSHAQPPQQAPIVESGQPAS
                     TLSSGYTYPTATGVQPESSASIVTSYPPPSYNPTCTAYTAPSYPNYDASVYSAASPFY
                     PPAQPPPPPGPPQQLPPPPAPAGSGSSPRADSKPPLPSKLPRPKAGPRQLQLHYCDIC
                     KISCAGPQTYREHLGGQKHRKKEAAQKTGVQPNGSPRGVQAQLHCDLCAVSCTGADAY
                     AAHIRGSKHQKVFKLHAKLGKPIPTLEPALATESPPGAEAKPTSPTGPSVCASSRPAL
                     AKRPVASKALCEGPPEPQAAGCRPQWGKPAQPKLEGPGAPTQGGSKEAPAGCSDAQPV
                     GPEYVEEVFSDEGRVLRFHCKLCECSFNDLNAKDLHVRGRRHRLQYRKKVNPDLPIAT
                     EPSSRARKVLEERMRKQRHLAEERLEQLRRWHAERRRLEEEPPQDVPPHAPPDWAQPL
                     LMGRPESPASAPLQPGRRPASSDDRHVMCKHATIYPTEQELLAVQRAVSHAERALKLV
                     SDTLAEEDRGRREEEGDKRSSVAPQTRVLKGVMRVGILAKGLLLRGDRNVRLALLCSE
                     KPTHSLLRRIAQQLPRQLQMVTEDEYEVSSDPEANIVISSCEEPRMQVTISVTSPLMR
                     EDPSTDPGVEEPQADAGDVLSPKKCLESLAALRHARWFQARASGLQPCVIVIRVLRDL
                     CRRVPTWGALPAWAMELLVEKAVSSAAGPLGPGDAVRRVLECVATGTLLTDGPGLQDP
                     CERDQTDALEPMTLQEREDVTASAQHALRMLAFRQTHKVLGMDLLPPRHRLGARFRKR
                     QRGPGEGEEGAGEKKRGRRGGEGLV"
     exon            75..285
                     /gene="ZFR2"
                     /gene_synonym="KIAA1086"
                     /inference="alignment:Splign:2.1.0"
     exon            286..400
                     /gene="ZFR2"
                     /gene_synonym="KIAA1086"
                     /inference="alignment:Splign:2.1.0"
     exon            401..619
                     /gene="ZFR2"
                     /gene_synonym="KIAA1086"
                     /inference="alignment:Splign:2.1.0"
     exon            620..873
                     /gene="ZFR2"
                     /gene_synonym="KIAA1086"
                     /inference="alignment:Splign:2.1.0"
     exon            874..1056
                     /gene="ZFR2"
                     /gene_synonym="KIAA1086"
                     /inference="alignment:Splign:2.1.0"
     exon            1057..1234
                     /gene="ZFR2"
                     /gene_synonym="KIAA1086"
                     /inference="alignment:Splign:2.1.0"
     exon            1235..1392
                     /gene="ZFR2"
                     /gene_synonym="KIAA1086"
                     /inference="alignment:Splign:2.1.0"
     exon            1393..1512
                     /gene="ZFR2"
                     /gene_synonym="KIAA1086"
                     /inference="alignment:Splign:2.1.0"
     exon            1513..1652
                     /gene="ZFR2"
                     /gene_synonym="KIAA1086"
                     /inference="alignment:Splign:2.1.0"
     exon            1653..1761
                     /gene="ZFR2"
                     /gene_synonym="KIAA1086"
                     /inference="alignment:Splign:2.1.0"
     exon            1762..1952
                     /gene="ZFR2"
                     /gene_synonym="KIAA1086"
                     /inference="alignment:Splign:2.1.0"
     exon            1953..2124
                     /gene="ZFR2"
                     /gene_synonym="KIAA1086"
                     /inference="alignment:Splign:2.1.0"
     exon            2125..2263
                     /gene="ZFR2"
                     /gene_synonym="KIAA1086"
                     /inference="alignment:Splign:2.1.0"
     exon            2264..2358
                     /gene="ZFR2"
                     /gene_synonym="KIAA1086"
                     /inference="alignment:Splign:2.1.0"
     exon            2359..2454
                     /gene="ZFR2"
                     /gene_synonym="KIAA1086"
                     /inference="alignment:Splign:2.1.0"
     exon            2455..2566
                     /gene="ZFR2"
                     /gene_synonym="KIAA1086"
                     /inference="alignment:Splign:2.1.0"
     exon            2567..2664
                     /gene="ZFR2"
                     /gene_synonym="KIAA1086"
                     /inference="alignment:Splign:2.1.0"
     exon            2665..4766
                     /gene="ZFR2"
                     /gene_synonym="KIAA1086"
                     /inference="alignment:Splign:2.1.0"
     regulatory      4747..4752
                     /regulatory_class="polyA_signal_sequence"
                     /gene="ZFR2"
                     /gene_synonym="KIAA1086"
                     /note="hexamer: AATAAA"
     polyA_site      4766
                     /gene="ZFR2"
                     /gene_synonym="KIAA1086"
                     /note="major polyA site"
ORIGIN      
        1 aggctcgggg aagacgccaa gatggcgacg agtcagtatt tcgacttcgc gcagggcggc
       61 ggcccgcagt acagcgccca gcctccgacc cttcccctgc ccactgtggg ggccagctat
      121 actgcacaac ccactcctgg gatggaccct gccgtgaacc cggcctttcc cccagctgcc
      181 ccggcagggt acggtggata ccagccccac tccggccagg acttcgccta cggcagccga
      241 ccccaggagc ccgtccccac ggccaccacc atggctacct accaggacag ttacagctac
      301 ggacagtcag cagctgccag gagctatgag gacaggccgt acttccagtc tgctgccctc
      361 cagtctgggc gcatgacagc cgcagactcc ggccagccag ggacccaaga agcctgcggg
      421 cagcccagcc cccatggcag tcacagccac gctcagcccc cacagcaggc gcccatagtg
      481 gagtccggac agccagcgag caccttgtcc tcgggataca cctaccccac ggcgacaggc
      541 gtccagcccg agtcgtcagc ttccatcgtg acctcctacc ccccgccctc ctacaacccc
      601 acctgcaccg cctacacggc accaagctac ccgaactatg acgcgtcggt gtactccgct
      661 gccagccctt tctatcctcc agcgcagccc ccgcctcccc cgggaccccc gcagcagctg
      721 cccccgccgc ccgcgcctgc aggctcagga agcagcccca gggccgactc gaagccaccg
      781 cttcccagca agctgccgag acccaaggcg gggcccaggc agctccagct tcactactgc
      841 gacatctgca agatcagctg cgctggcccc cagacctacc gggaacatct gggagggcag
      901 aagcacagaa agaaggaggc ggcccagaag acaggcgtgc agcccaacgg gagcccgcgc
      961 ggggtgcagg cgcagctgca ttgcgacctg tgcgccgtgt cctgcaccgg ggcggacgcc
     1021 tacgcggccc acatccgggg atccaagcac cagaaggtct tcaagctgca cgccaaactg
     1081 gggaagccca ttcccaccct cgagcctgca ctggccacag agagcccccc cggggcagag
     1141 gccaagccca cgtcccccac tggccccagc gtgtgtgcct cgagcaggcc agcgctggcc
     1201 aagagacccg tggcctcgaa ggccttatgc gaggggcctc ctgagccaca ggcagcaggc
     1261 tgcagacccc agtgggggaa accagcccaa cctaaattag agggtcccgg agcacctacc
     1321 caaggaggct caaaggaagc tcccgcgggc tgctctgatg cgcagccggt gggcccggaa
     1381 tatgtggagg aggtgttcag cgacgaaggg cgagtgcttc gcttccactg caagctgtgc
     1441 gagtgcagtt tcaacgacct taacgcgaag gacctgcacg tgagggggcg gcggcaccgg
     1501 ctgcagtacc ggaagaaagt gaacccggac cttcccattg ccacggagcc cagcagccgg
     1561 gctcggaagg tcctggagga gcgcatgagg aagcagcggc acctggcgga ggagcggctg
     1621 gagcagctgc ggcgctggca cgcggagagg aggcggctgg aggaggagcc accccaggac
     1681 gtgccgcccc acgcgccgcc cgactgggcc cagcctctgc tcatgggcag gccggagtca
     1741 cccgccagcg ccccactcca gcccgggcgg cggccggcgt ccagcgacga ccggcacgtc
     1801 atgtgcaagc acgccaccat ctaccccacg gagcaggagc tcctggccgt gcagagggcc
     1861 gtgtcccacg cagagcgggc cctcaagctg gtgtccgaca cactggccga ggaggaccgg
     1921 ggccgccgag aggaagaggg tgacaagcgc agcagcgttg ccccccagac tcgggtcctg
     1981 aaaggcgtca tgcgagtagg catcctggcg aaaggcctcc tcctgcgtgg ggacaggaac
     2041 gtgcgcctcg ctctgctctg ctccgagaag cccacgcaca gcctgctgcg gaggatcgcc
     2101 cagcagctgc cccggcagct ccagatggtg accgaggatg agtatgaggt ctcctccgac
     2161 cctgaagcca acattgtcat ctcctcctgt gaggagccca ggatgcaggt caccatatct
     2221 gtcacctcac ctctgatgcg ggaggacccc tccacagacc caggtgtgga ggagcctcag
     2281 gctgatgcag gtgatgtcct gagccccaag aagtgcctcg agtccctggc cgccctccgt
     2341 catgccaggt ggtttcaggc tcgagccagc ggcctgcagc catgcgtgat cgtcatcagg
     2401 gtcctgaggg acctctgccg gcgtgtgccc acctgggggg ccctgccagc ctgggccatg
     2461 gagctgctgg tggagaaggc tgtgagcagt gcggctgggc ccctgggccc cggggatgca
     2521 gtcaggcgag tcctggagtg cgtggccaca gggacgctcc tgacagacgg gcccgggctc
     2581 caggatccct gcgagagaga ccagacagat gccctcgagc ccatgaccct ccaagagcgg
     2641 gaagacgtga ccgccagcgc ccagcacgcc ctgcgaatgc tggccttccg gcagacccac
     2701 aaggtcctgg gcatggatct cctgccgccc agacaccggc tgggggcccg cttccggaag
     2761 aggcaacggg gacctggcga gggagaggag ggcgcagggg agaagaagcg gggccggcgg
     2821 ggcggagagg ggctcgtgtg agccgcctac ctcccccacc tgcgggcctt tgcatccctg
     2881 cactcctgga cgtgtgcgcg ccgaccaatg gctgcttcat ccccgacgtt ggacaatggt
     2941 catttccttt tgagtaacgc tctgtaggtt tcctttaaaa cacctgtgct tcagaccggg
     3001 cactgtggct catgccttta atcccagcac tttgggaggc tgagttgctt gagcctgaga
     3061 gttcaaggcc agcccagaca acagagtgag acccccatct ctccaaaata tttttaaaaa
     3121 tcagcttggc atggttggtg gccaggcgcg gtgattcacg cctgtaatcc cagcactttg
     3181 agaggccgag gtgggcagat cgcctgaggt caggagttcg agaccggcct ggtcaacatg
     3241 gtgaaaccct gtctctagta aaaaacacaa caattagcct ggcgtggtgg tgtgcacctg
     3301 tagtcccagc tacttgggag gctgagtccg gagccttgag gccaggaggg cagtgagctg
     3361 tgattgcacc gtgacactcc agcctgggca acagaagaag actttgtcac ttaaaagaaa
     3421 tgttttttaa catttgtgct taaattgtta cagaaatgac accatccagc cctgggagtg
     3481 gcaccccttc ctcgagggcc ccatccccca cagccagggg ggccagcagt acagcaagca
     3541 gattctaaac tcgggggcat cttgctggct ctaaactcac ctcgtggtac aggaaggggt
     3601 tttaaaatac ttcctctggg ctgcgcatgg tggctcacac ctataatccc agcactttgg
     3661 gaggccaagc ttggtggatc gcttgagccc agcggtttaa gatcagtctg ggcaatatgg
     3721 tgacacccca tctctacaaa aaattagcca gttgtggtgg cccaagcctg tagtcccagc
     3781 tactcgggag gctgaggccg taggatccct tgagcccagg agttcgaggc tgcagcgagc
     3841 cgagattgcg ctactgaact ccagcctggg ttacagagcg agaccctgtc tcaaagaaac
     3901 aaacaaacaa acaaacaaac aaacaaaact ttctttggat gcggctgcgg catggatttg
     3961 aaatcacgtg ggcaggccct gttctggggc cccaccacat gtgcaggaca agcccagggg
     4021 agctcccagc cggcatcccc acgcccccag cccagcctgc tccaaacaga ccccccaccc
     4081 acctccacag ccaggatgtc agcagggcct gagccaggct cgtcccctgt ggggagagcc
     4141 acagggccag gtggacacgc cgacgggcga tgaggatcct ggctgggcct cccccgggaa
     4201 cagctgtgct ggacagtcag acccggagcc cagaggcacc cccacccacc ccccgccccg
     4261 agccctgtac cactgagtgc ctttcacaga gaaaacccac tctgccatgt gtcactgagg
     4321 cctggatttg agcttccgtc cttccttcct ccctctctcc ctgatgtagg ccttggctgg
     4381 ccctgaggca gggggtcccc aatcccccct tgtggtagca gggcccggga cccgtgcctg
     4441 ggggacccgg ggaggggccg ccgtcttgtg gatgctggcc atggtgggca ggcgcctcct
     4501 ggcactgatg gatgtggggg cacccccttc tgagtcccca ccccaacctg ttcaaacctt
     4561 ccgcttggtc agtttttttt tctttggcca gctgcccagt ggcattgaat gagaaaagtc
     4621 cacctttggg cagatgtgat ctccagccag tggctcagtt ttgtttctct gtgtttgaag
     4681 gacagcctgc atgtggctct gtctgaatgt ctttgtagag ctacctggaa attgggaggc
     4741 agggggaata aaggaaatca tttgtc
//
