LOCUS       NM_173832               4786 bp    mRNA    linear   PRI 07-APR-2024
DEFINITION  Homo sapiens ZFP41 zinc finger protein (ZFP41), transcript variant
            1, mRNA.
ACCESSION   NM_173832 XM_940886 XM_944871
VERSION     NM_173832.6
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 4786)
  AUTHORS   Teng,Y., Xu,J., Wang,Y., Wen,N., Ye,H. and Li,B.
  TITLE     Combining a glycolysis-related prognostic model based on scRNA-Seq
            with experimental verification identifies ZFP41 as a potential
            prognostic biomarker for HCC
  JOURNAL   Mol Med Rep 29 (5) (2024)
   PUBMED   38516783
  REMARK    GeneRIF: Combining a glycolysis-related prognostic model based on
            scRNA-Seq with experimental verification identifies ZFP41 as a
            potential prognostic biomarker for HCC.
REFERENCE   2  (bases 1 to 4786)
  AUTHORS   Luck,K., Kim,D.K., Lambourne,L., Spirohn,K., Begg,B.E., Bian,W.,
            Brignall,R., Cafarelli,T., Campos-Laborie,F.J., Charloteaux,B.,
            Choi,D., Cote,A.G., Daley,M., Deimling,S., Desbuleux,A., Dricot,A.,
            Gebbia,M., Hardy,M.F., Kishore,N., Knapp,J.J., Kovacs,I.A.,
            Lemmens,I., Mee,M.W., Mellor,J.C., Pollis,C., Pons,C.,
            Richardson,A.D., Schlabach,S., Teeking,B., Yadav,A., Babor,M.,
            Balcha,D., Basha,O., Bowman-Colin,C., Chin,S.F., Choi,S.G.,
            Colabella,C., Coppin,G., D'Amata,C., De Ridder,D., De Rouck,S.,
            Duran-Frigola,M., Ennajdaoui,H., Goebels,F., Goehring,L., Gopal,A.,
            Haddad,G., Hatchi,E., Helmy,M., Jacob,Y., Kassa,Y., Landini,S.,
            Li,R., van Lieshout,N., MacWilliams,A., Markey,D., Paulson,J.N.,
            Rangarajan,S., Rasla,J., Rayhan,A., Rolland,T., San-Miguel,A.,
            Shen,Y., Sheykhkarimli,D., Sheynkman,G.M., Simonovsky,E., Tasan,M.,
            Tejeda,A., Tropepe,V., Twizere,J.C., Wang,Y., Weatheritt,R.J.,
            Weile,J., Xia,Y., Yang,X., Yeger-Lotem,E., Zhong,Q., Aloy,P.,
            Bader,G.D., De Las Rivas,J., Gaudet,S., Hao,T., Rak,J.,
            Tavernier,J., Hill,D.E., Vidal,M., Roth,F.P. and Calderwood,M.A.
  TITLE     A reference map of the human binary protein interactome
  JOURNAL   Nature 580 (7803), 402-408 (2020)
   PUBMED   32296183
REFERENCE   3  (bases 1 to 4786)
  AUTHORS   Yin,Y., Morgunova,E., Jolma,A., Kaasinen,E., Sahu,B.,
            Khund-Sayeed,S., Das,P.K., Kivioja,T., Dave,K., Zhong,F.,
            Nitta,K.R., Taipale,M., Popov,A., Ginno,P.A., Domcke,S., Yan,J.,
            Schubeler,D., Vinson,C. and Taipale,J.
  TITLE     Impact of cytosine methylation on DNA binding specificities of
            human transcription factors
  JOURNAL   Science 356 (6337) (2017)
   PUBMED   28473536
REFERENCE   4  (bases 1 to 4786)
  AUTHORS   Noce,T., Fujiwara,Y., Sezaki,M., Fujimoto,H. and Higashinakagawa,T.
  TITLE     Expression of a mouse zinc finger protein gene in both
            spermatocytes and oocytes during meiosis
  JOURNAL   Dev Biol 153 (2), 356-367 (1992)
   PUBMED   1397691
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AK096024.1, DA216172.1, CR992458.1, KF458885.1, AC138696.4 and
            AW576245.1.
            
            On Jul 14, 2018 this sequence version replaced NM_173832.5.
            
            Transcript Variant: This variant (1) represents the longer
            transcript. Both variants 1 and 2 encode the same protein.
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK096024.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA1965299, SAMEA1968540
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            CDS uses downstream in-frame AUG :: upstream AUG and CDS extension
                                                is not conserved
            MANE Ensembl match               :: ENST00000330701.7/
                                                ENSP00000327427.6
            NMD candidate                    :: translation inferred from
                                                conservation
            RefSeq Select criteria           :: based on conservation,
                                                expression, longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-356               AK096024.1         1-356
            357-895             DA216172.1         12-550
            896-1220            CR992458.1         353-677
            1221-1920           AK096024.1         1221-1920
            1921-2122           KF458885.1         43-244
            2123-4298           AC138696.4         121245-123420
            4299-4786           AW576245.1         17-504              c
FEATURES             Location/Qualifiers
     source          1..4786
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="8"
                     /map="8q24.3"
     gene            1..4786
                     /gene="ZFP41"
                     /gene_synonym="zfp-41; ZNF753"
                     /note="ZFP41 zinc finger protein"
                     /db_xref="GeneID:286128"
                     /db_xref="HGNC:HGNC:26786"
     exon            1..204
                     /gene="ZFP41"
                     /gene_synonym="zfp-41; ZNF753"
                     /inference="alignment:Splign:2.1.0"
     exon            205..1855
                     /gene="ZFP41"
                     /gene_synonym="zfp-41; ZNF753"
                     /inference="alignment:Splign:2.1.0"
     CDS             359..955
                     /gene="ZFP41"
                     /gene_synonym="zfp-41; ZNF753"
                     /codon_start=1
                     /product="zinc finger protein 41 homolog"
                     /protein_id="NP_776193.3"
                     /db_xref="CCDS:CCDS6397.3"
                     /db_xref="GeneID:286128"
                     /db_xref="HGNC:HGNC:26786"
                     /translation="MEKPAGRKKKTPTPREEADVQKSALREEKVSGDRKPPERPTVPR
                     KPRTEPCLSPEDEEHVFDAFDASFKDDFEGVPVFIPFQRKKPYECSECGRIFKHKTDH
                     IRHQRVHTGEKPFKCAQCGKAFRHSSDVTKHQRTHTGEKPFKCGECGKAFNCGSNLLK
                     HQKTHTGEKPYECTHCGKAFAYSSCLIRHQKRHPRKKP"
     exon            1856..4786
                     /gene="ZFP41"
                     /gene_synonym="zfp-41; ZNF753"
                     /inference="alignment:Splign:2.1.0"
     regulatory      4763..4768
                     /regulatory_class="polyA_signal_sequence"
                     /gene="ZFP41"
                     /gene_synonym="zfp-41; ZNF753"
                     /note="hexamer: AGTAAA"
     polyA_site      4786
                     /gene="ZFP41"
                     /gene_synonym="zfp-41; ZNF753"
                     /note="major polyA site"
ORIGIN      
        1 atttcctgcc ggtgcctagg gccgacgggg acgctggcac tggtggggag ctgttggggg
       61 gtcccgcatc tagggctctc ctttcctgcc tccggccccc gcgaggggcg cgcgcctctc
      121 cccgccctcc agcagtcctg gtagggcccg ggcgcgtccg cgctctgcag cgggaggtcc
      181 tcgtcgcctc tcgtctccag ccagcaccaa gaggatggtg gcccttggcc tcctggtgca
      241 gagcatcagt cccacgctgg gagtgtggag aggtgcgtgg gaagcaagcc attgaggaag
      301 tggggccaac agagaggtca gcagcccctt agccctcacg cttccaagga acagaatgat
      361 ggagaagcct gcaggcagaa aaaagaagac gccgacccca agggaggagg cagacgtgca
      421 gaagagtgcg ctcagagagg agaaggtgtc cggggacaga aagccacctg agaggcccac
      481 tgtgcccagg aagccccgca cagagccctg cctgagtcct gaagacgaag agcacgtctt
      541 tgatgccttc gacgcttcat ttaaagatga ctttgagggg gttcccgtgt tcattccttt
      601 tcagaggaag aaaccctatg agtgcagtga gtgtgggcgg atctttaagc acaagacaga
      661 ccacattcgc catcagaggg tccacactgg agagaagccc ttcaagtgtg cgcagtgcgg
      721 gaaggccttc cggcacagct ctgacgtcac caaacaccag aggactcaca cgggagagaa
      781 gcccttcaaa tgcggggagt gcgggaaagc ctttaactgc ggctccaatc tcctgaaaca
      841 tcagaagacg cacaccgggg agaagcccta cgaatgcacg cactgtggga aagcctttgc
      901 ctacagctcc tgtctcatcc gccatcagaa acgccaccct cggaagaagc cctgagccgg
      961 ggccatctgc ggactcgggc cctgcggtgc gagcctcgcc ggacacctgc tccgtggctc
     1021 cctcgtgtcc cgcgtctgat gggggcgcag ggccgtgcgc actgtgttcc gtgccctggg
     1081 gacccccgga aaagcagccc agtcagatgt gggaacgtgc cagcgaggga gagacctttc
     1141 cactgcagag agtctctctg atcaagacac cgcagtgatg gagaagccac cagaggctcc
     1201 ttgcagccac agagcatttt ccaagttccc gatggcgaac ggggctcagc accagagacc
     1261 agggagtatt cactgccatc cattggacgt gtttgggtca cctcagagca cccagcagga
     1321 gaggctcctg gtgtagtggg cagcccagca cttcccgctg ctgcctgcct gtgatgtcca
     1381 ctctgcttaa gcctttcatc tgccgctgaa ggccccagtc tggactctct gccctctggg
     1441 tccccgagct ctgcagcgag ccctgggacc actcatccct gcccagccag cttcagtgcc
     1501 cggggccgct tgtccctgcc cggcctctgt gccccaactg tgcttggtcc tctggcttct
     1561 ctcctcctgc tggagtgcca gtccctgagc tcagaccccc gtccccggaa ctgggccaca
     1621 ccacgtgccc tcttggccca gccttcctcc cagagaggcg gcctgactta cctggatgga
     1681 cttgggacaa aggttcctca ggaccttgga caccaccacc tgctgagctt cccgtcccag
     1741 ccatgcagtg gggcccctgg ggtgccctcg gcagcttcgg tccagcctgc atctgcccct
     1801 cggccttccg acgtgggcgg tgggccccag ccccacagac cagcccagca ttcaggctgg
     1861 tagagcagat cacccccaaa gcaagaagtt ccagatgaaa tatgcataag aagcagcctc
     1921 aaaactaaca aaaaagattc gcacattcct cagttagagg aggagcagag atgaagaaaa
     1981 ggagaagaaa agcgctggaa agagaagaaa aggaacctcc ttctgtgcag caggctcctg
     2041 gcccagggag tgcggtgtgc ggcagagtgc gtgcagggaa gcagcctctg aaatcgtgca
     2101 gggaagcacc ctgtgaaatc gtgcagggaa gcaccctgtg aaatcgtgca gggaagcacc
     2161 ctgtgaagtc gtgcagggaa gcaccctctg aaatcgtgca gggaagcacc ctctgaaatc
     2221 gtgcagggaa gcaccctgtg aagtcgtgca gggaagcacc ttctgaaatc gtgcagggaa
     2281 gcaccctctg aaatcgtgca gggaagcacc ctctgaaatg cctagaaata gctgccgggc
     2341 tttcacttgg ttcccaaatt tcttcaaagg tcaaaaccat cacagtgggc aactttacac
     2401 cccagtgttc actgtcctca ggccactgca gagccatcct agtggggcag tgggcgcggg
     2461 gcgggggctc ctgactccgg tgaggtcacc ctggagggga gtcccaggaa tcagcctgat
     2521 gttcagaatg ccttcctggc atctcagaag tgtactgggg gagacgtgag gacctttcag
     2581 ccaagtgtca gcgttcttat tgcaggagaa cattaaagcc acaacccaga aacttctcag
     2641 gagcatggcg cacccacacc agccccgggc tccgcctgga cagcacctcc tgggccgccc
     2701 tgaccagcag acaccatcct tccagcctct cttggccacc cggaccagcg ggcaccaccc
     2761 tcccagcctc acgcggccac cctgaccagc aggcaccatc cttccagcct tgctcagtca
     2821 ccctgaccca gagggctgcc ctgaccagcg ggcaccatcc tcccagcccc actcagctgc
     2881 cctgaccagc gggcaccatc ctcccagcct cactcggcca gccgagctct gtaggcctca
     2941 gagtgcagag aacctcaaat gttgtgactt tgctctgctg cagggacctg ccatggagtg
     3001 tcccttgtgc gagcattttg agagctatgc cagcatccat ccctgcaggt cccatccctg
     3061 agccatttct caggagagca ggaagggagc agggagaggg gtgctcccag ccagccccgg
     3121 aaccagaggt ctggggacgc agccgaccag ccctccttgt ctgggcctct gtttcctctt
     3181 cgacacaggg aagcagggag gggccgatca gcgacttagg cctgttggct gtggtggggt
     3241 ccacctgcgt ttctggggag cccacggacc ctggggtgta cctgggtttc attcccagtg
     3301 acctctccta ttggtcccca tttggggcgc tgagatgtga tcgtttcttt cctgagaatg
     3361 agctgaggta aaaacatgct ggggaggaag atgggccctg ggggcagcga gctgcgcctc
     3421 tgcaccggga gaaaggccgt gtccccagag ctgaggcggt ggtgggcagg gctcctgaga
     3481 agccggggca gggcagggtg tctctgaggt caatgaggaa cagctgaggt ccagggacgc
     3541 aggaaggatg gggtgaactc cgggatgggg ccggcaggga gcctcacgct tacagagcct
     3601 ggtgttggca ctctcctggc ttcctccgca aacctagcca cgtggtcagg gagcccgggc
     3661 ctagcagacg gcccccacct tgacagaatc cccagggtcg tgcgtggcgg tgggggcgac
     3721 ttcacagccg agaccgggcc taacgctgct gtctcgcagt cacccctgca ggccgctcag
     3781 ggcagggctc tggcctgacg ggggttcctg gacacgcctc tgagccggca gcccctaccc
     3841 gcacccgtgc accttccacg cccgtctcca gcagcccctg cccccacccg cacccctgca
     3901 cctgccacgc ctgtctccgg cagcccctgc ccgcacccgc acccctgcac ctgccacgcc
     3961 cgtctccggc agcacctgcc acgcccgtct ccggcagcac ctgccacgcc cgtctccggc
     4021 agcacctgcc acgcccgtct ccggcagccc ctgcccgcac ccgcacccct gcacctgcca
     4081 cgcccgtctc cggcagcccc tgcctgcacc cgcacccctc acggctgtct ccggcagccc
     4141 ctgcccgcgc ccgcacctct gcacctccca cgcccctctc cggcagcccc tgcccacacc
     4201 cgcacccctg cacctcccac gcccgtcttg ccctggggcc caggtgcagg tctgtgagga
     4261 gggcagcccc gtgctcccgt ggccaccgct cagccaaatg gattcagcga gggtttttag
     4321 tgtttgtgcc tgtgtccccg tgtgcctgtt tcctggtgag gctggatgcc tggcatgtct
     4381 gaacactcac attccccagg catgcatgtg cagccgccgc cgccacccat gtactgtggc
     4441 gctgacccct cctgtaacag ctgtggtctt ggcctctcgt gttggtggca gatgtcccat
     4501 ttcccagtta ctttctgttg tccaaaagtt taactgtcct gccagccaaa gctgctgagc
     4561 attactctga tagaccatca gtccttggta agtgtcctgt gcatctggga taagcatccg
     4621 tttgttttca gctgcgcttt ctgtgacttg ctctgcgtga gtcctcggtc cacgtgggcc
     4681 gttgcgctgg ttcccagcct gcccgacaca ctcactgcga cgcctccctt gcctactgct
     4741 tgctggcttc tgtgttctct gcagtaaaca ttgatttctg actcga
//
