LOCUS       NM_153018               4987 bp    mRNA    linear   PRI 04-APR-2024
DEFINITION  Homo sapiens ZFP3 zinc finger protein (ZFP3), mRNA.
ACCESSION   NM_153018
VERSION     NM_153018.3
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 4987)
  AUTHORS   Luck,K., Kim,D.K., Lambourne,L., Spirohn,K., Begg,B.E., Bian,W.,
            Brignall,R., Cafarelli,T., Campos-Laborie,F.J., Charloteaux,B.,
            Choi,D., Cote,A.G., Daley,M., Deimling,S., Desbuleux,A., Dricot,A.,
            Gebbia,M., Hardy,M.F., Kishore,N., Knapp,J.J., Kovacs,I.A.,
            Lemmens,I., Mee,M.W., Mellor,J.C., Pollis,C., Pons,C.,
            Richardson,A.D., Schlabach,S., Teeking,B., Yadav,A., Babor,M.,
            Balcha,D., Basha,O., Bowman-Colin,C., Chin,S.F., Choi,S.G.,
            Colabella,C., Coppin,G., D'Amata,C., De Ridder,D., De Rouck,S.,
            Duran-Frigola,M., Ennajdaoui,H., Goebels,F., Goehring,L., Gopal,A.,
            Haddad,G., Hatchi,E., Helmy,M., Jacob,Y., Kassa,Y., Landini,S.,
            Li,R., van Lieshout,N., MacWilliams,A., Markey,D., Paulson,J.N.,
            Rangarajan,S., Rasla,J., Rayhan,A., Rolland,T., San-Miguel,A.,
            Shen,Y., Sheykhkarimli,D., Sheynkman,G.M., Simonovsky,E., Tasan,M.,
            Tejeda,A., Tropepe,V., Twizere,J.C., Wang,Y., Weatheritt,R.J.,
            Weile,J., Xia,Y., Yang,X., Yeger-Lotem,E., Zhong,Q., Aloy,P.,
            Bader,G.D., De Las Rivas,J., Gaudet,S., Hao,T., Rak,J.,
            Tavernier,J., Hill,D.E., Vidal,M., Roth,F.P. and Calderwood,M.A.
  TITLE     A reference map of the human binary protein interactome
  JOURNAL   Nature 580 (7803), 402-408 (2020)
   PUBMED   32296183
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BP250703.1, BX647638.1 and AC012146.25.
            
            On Nov 22, 2018 this sequence version replaced NM_153018.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR1660809.78809.1,
                                           SRR1660809.144857.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA1965299, SAMEA1966682
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000318833.4/ ENSP00000320347.3
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-323               BP250703.1         9-331
            324-1731            BX647638.1         285-1692
            1732-4742           AC012146.25        84958-87968         c
            4743-4987           BX647638.1         4699-4943
FEATURES             Location/Qualifiers
     source          1..4987
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="17"
                     /map="17p13.2"
     gene            1..4987
                     /gene="ZFP3"
                     /gene_synonym="ZNF752"
                     /note="ZFP3 zinc finger protein"
                     /db_xref="GeneID:124961"
                     /db_xref="HGNC:HGNC:12861"
                     /db_xref="MIM:194480"
     exon            1..109
                     /gene="ZFP3"
                     /gene_synonym="ZNF752"
                     /inference="alignment:Splign:2.1.0"
     exon            110..4987
                     /gene="ZFP3"
                     /gene_synonym="ZNF752"
                     /inference="alignment:Splign:2.1.0"
     CDS             118..1626
                     /gene="ZFP3"
                     /gene_synonym="ZNF752"
                     /note="zinc finger protein homologous to Zfp-3 in mouse;
                     zinc finger protein-3; zfp-3; zinc finger protein 752"
                     /codon_start=1
                     /product="zinc finger protein 3 homolog"
                     /protein_id="NP_694563.1"
                     /db_xref="CCDS:CCDS11067.1"
                     /db_xref="GeneID:124961"
                     /db_xref="HGNC:HGNC:12861"
                     /db_xref="MIM:194480"
                     /translation="MGTENKEVIPKEEISEESEPHGSLLEKFPKVVYQGHEFGAGCEE
                     DMLEGHSRESMEEVIEQMSPQERDFPSGLMIFKKSPSSEKDRENNESERGCSPSPNLV
                     THQGDTTEGVSAFATSGQNFLEILESNKTQRSSVGEKPHTCKECGKAFNQNSHLIQHM
                     RVHSGEKPFECKECGKTFGTNSSLRRHLRIHAGEKPFACNECGKAFIQSSHLIHHHRI
                     HTGERPYKCEECGKAFSQNSALILHQRIHTGEKPYECNECGKTFRVSSQLIQHQRIHT
                     EERYHECNECGKAFKHSSGLIRHQKIHTGEKPYLCNECGKGFGQSSELIRHQRIHTGD
                     KPYECNECGKTFGQNSEIIRHIRIHTGEKPYVCKECGKAFRGNSELLRHERIHTGEKP
                     YECFECGKAFRRTSHLIVHQRIHTGEKPHQCNECARTFWDNSELLLHQKIHIGEKPYE
                     CSECEKTFSQHSQLIIHQRIHTGEKPYECQECQKTFSRSSHLLRHQSVHCME"
     regulatory      4959..4964
                     /regulatory_class="polyA_signal_sequence"
                     /gene="ZFP3"
                     /gene_synonym="ZNF752"
                     /note="hexamer: AATAAA"
     polyA_site      4987
                     /gene="ZFP3"
                     /gene_synonym="ZNF752"
                     /note="major polyA site"
ORIGIN      
        1 gatgcccgtc gccagtgaca ccgggacaac agctgcgggc tctgtgcgag cggcccagca
       61 gcgcggagcc tcagcggagt gagcgagcgc ggggcagtag cggcctgcga ttgtgagatg
      121 gggactgaga acaaggaggt gattcccaag gaagaaattt ctgaagaatc tgagccacat
      181 gggtcattat tagaaaaatt tccaaaagtg gtttaccaag gtcatgagtt tggagcagga
      241 tgtgaagaag acatgttgga gggacattcg agagagtcca tggaagaggt tatagagcag
      301 atgtctcctc aggagagaga ctttccatca gggttgatga tctttaagaa atcaccctca
      361 agtgagaaag accgggagaa taatgagagt gagagaggct gcagtcccag cccaaatctg
      421 gttacacatc agggagatac aacagaggga gttagtgcat ttgctacctc tggccaaaac
      481 ttcctagaga ttttagaatc taacaaaaca cagagaagtt ctgtgggaga aaagcctcat
      541 acatgtaaag aatgtgggaa agcctttaat cagaactcac atctcatcca gcatatgaga
      601 gttcatagtg gagaaaaacc ctttgaatgt aaagaatgtg gaaagacatt tggaactaat
      661 tcaagccttc gacggcacct gagaattcat gctggagaaa aaccctttgc ttgtaatgaa
      721 tgtggaaagg ccttcattca gagttcacac cttattcacc atcatagaat tcatactgga
      781 gagagaccct ataaatgtga agaatgtggt aaagccttca gtcaaaattc agcccttatt
      841 ctacaccaga gaatccatac tggagagaaa ccatatgaat gtaatgaatg tgggaagacc
      901 tttagggtta gttcacagct tattcagcat cagagaattc atactgaaga aagataccat
      961 gaatgcaatg agtgtggcaa agccttcaag catagctcag gccttattag acaccagaaa
     1021 attcatactg gagaaaaacc atatctgtgt aatgaatgtg ggaagggctt cgggcagagt
     1081 tctgagctta tccggcatca gagaattcat acaggggaca aaccctatga atgtaatgaa
     1141 tgtgggaaaa cttttggcca gaactcagag attattagac atattagaat tcatactggt
     1201 gagaagccct atgtatgtaa ggaatgtggg aaggccttca gggggaactc agaacttctt
     1261 agacatgaga gaattcacac tggagagaaa ccctatgaat gctttgagtg tggaaaggct
     1321 ttcaggcgga cctctcacct tattgtccac cagagaattc atactggaga gaaaccccat
     1381 caatgtaatg agtgtgcaag aaccttttgg gataattctg agctgcttct ccaccagaaa
     1441 attcatattg gagagaaacc ttatgaatgt agcgagtgtg agaaaacatt tagccagcat
     1501 tcccaactta tcatacatca gagaattcac actggagaga agccttatga gtgccaagaa
     1561 tgtcagaaga cttttagtcg gagctctcac ctcctccgac atcaaagtgt tcactgtatg
     1621 gagtaatctg caaaatagga aagcttttag tggaaaagct aaagtccaac ttattcattt
     1681 gttcataata tgcaaatatg caccccaagt attcaaatcc aatgaatgga cagaacctcc
     1741 tctgtcctcc cactgatttt aaatagttgg ttgaagaaga tgaggcactt tttttttttt
     1801 ttttttaagc attggggtct tgctctgttg cccaggatgg gatgcagtgg cacagtcgta
     1861 actcactgct tccttgaact cctgggctca aacagtcctc ctgcctcagc cttccaaata
     1921 gctaggactg caggcactaa tgaggcactt ttatgaatta ttcattgaga ggtttcagtg
     1981 tgctaagtta aatcataaaa gctctttcag gccttaattt cccctctgtc cttccttccc
     2041 cttctcctcc cccagtggat cacataacaa acattaaggg tctgtaccag ccatctttcc
     2101 taaattactc ttcagcaaaa ttgtgggaac aggattccac cacctcctaa gaatgagagt
     2161 tgactcattg actgttaccc cctgaaatat tagaaagtca taatttagaa gacacacctc
     2221 attctcctgt ccactgttta gcattggaat aatttagtaa gctgttatta gcttcaaagt
     2281 cgtccagccc tgctatgaag ttactttaga agatggcagc attaatgaag aagcaggctc
     2341 atttcacatc tgtcaggctt ccttattcat ctgaagaggc tgccatgatg gaggaactga
     2401 caggcaattt acaacgggat tataagtgaa ggccttagaa tccagagggg ccgattaggc
     2461 aacaccaggg gataaacaat tgaggtcaca ctgctcggca tgggcagaag cagctcttca
     2521 ggagctgtcc acacttcagg ggtgctcaga ctgactgctc ctaagaattc tgctgcatat
     2581 atttttagcc ccatctcctg ccactgctga cagatattgt gacagtaagt agcagacagg
     2641 actgtggctt cacctcctcc gggcacctgg ctacagtgat gagtcagttc acctgatgac
     2701 aaaccagggt ctggccttgc caaagcactt aagttctcat gacctggacc gcactggagg
     2761 ccctggctaa gtcaggatgt cgtagcctct tcttggtttt gccccttggc cttgaaattc
     2821 ttttttcttg aataacttta aaaaaataga gataaagtct tgctatgttg cccaggctgg
     2881 tcttgaatgc ctgggctcca gcaatctttt tgcctcaact tcccaaagta ttgagattac
     2941 aggtgtgagc taccatgccc ggccttgaaa ttctttcttc gctatgtctg catgtttttt
     3001 gtgttctgta tttatttctt ctccaaggaa acagcctaca ttttccatgt gtccatgttt
     3061 ctgaggccgt gggtgacagt gggaattgca ctaatggggg cccaacaggc ctgggggctg
     3121 gtcttagcgc tagaccttga acaaggcact tcacctgctg gtctccaatt ttctcctctg
     3181 taaaatgaaa gagttgaact aagtgatctc aaaagtttca accagcccga taattcctta
     3241 attctttaaa aatttaactt tatatatctt tattattctt taacctcatc tttgttacac
     3301 taatattagt cactaatatt tattgagtgt ttactacctg acaggcagag tgccagttta
     3361 cattttaatt ttcacatcat ttctatgatg tgggtactca tttttttaaa gctttatgaa
     3421 ggtataattt acgtactata aaattcacct gttttaagtg ttcagttgaa tgatttttaa
     3481 tttacatagt ggtgcaacca tcaatgatgt gggtattctt accccaattt aaaagataag
     3541 aaggggcagt gttaagtaat tgacccatga ttccacagct agtaagagcg acagccaaga
     3601 ctccaaacct ggttgatgct cttaaccact gtgctatgcc gcaggtaggc agattcatta
     3661 ctgccttatc tgaaaccctt tgcacagttt ctattactga tttctatgta gatttgaata
     3721 taacaaattt aaatcatgtc cttggtaaca gaactgatca cagccaaaaa aaattcacca
     3781 aatgggttta ttctgtactc caatataggt gtcttcccag gtttatatcc ttggcttgag
     3841 aaaagggttg tacaaataga tgattgcaga gtttccacat ccttccagat acctctgcct
     3901 ctagcagtca cactcttagt aagggaagtt gtttgattta cttcttccct taggttgatt
     3961 acaagtgaag tgcgccgtct tattcctttt tcattgctgg agcacaaatt gaattgtgcc
     4021 cagaccgtat ctttctcaca tgaaacctgg atctcaccta tcccttccat gcctgattcc
     4081 cgtgtttgca tattttattt ccacatttac ctcttgtcag ccctgacaga gaatttggca
     4141 ccccttcaag cttctcctaa acaatctatg cacacaaaca cccctgagca atatggactt
     4201 cactgaagat agtgtgtaag caaaggagaa gagttcacat tgtgcatcct attagacatt
     4261 ttgttctcag aagtacctta ctggccaaac caatgaaggt tttcctcttg tcctcccctc
     4321 tcaaggctca gtcacctcaa cttctttttg cctactagat atccaatcca tcacctcgcc
     4381 tcccctggcc ctagctcaat taccctctta aacccattcc tgctcagcaa aacttcctct
     4441 agttcaccat tcattcattt gaacattagg aggcaattta gtgacctgtt gtacctgacc
     4501 atgttcttaa gggggaggtc tcacgtctca ttcccagaaa agtctaccat atatagatac
     4561 atattccccg ccccgcccca gatttctggt gaatgaaatc acttgtatct tattaggtac
     4621 atatacgcaa atccttaacc tcaattctct gtcctcttca tgtcttaccc agatatctca
     4681 ggaagatttc tcttttcctt ctgtttgcct ccctcttcga cttacttggg agtcagcatc
     4741 tgaccacagt cgtgactggt aatgatgatt tgtgcaaata ctatcaagga aaggacatga
     4801 attgtcttaa ttttagaccc attaaaaaac cgcacaggcc tcaatcttaa aagtcctatc
     4861 taaataccca gaaataccct tcagaatttt tgaagctatg cccatgtaca aaattttctt
     4921 ccttccctaa ttttaatggt atactaacac cttaggtaaa taaaatattt ctttactatt
     4981 ttattga
//
