LOCUS       NM_020917               7491 bp    mRNA    linear   PRI 04-APR-2024
DEFINITION  Homo sapiens ZFP14 zinc finger protein (ZFP14), transcript variant
            2, mRNA.
ACCESSION   NM_020917 XM_375604
VERSION     NM_020917.3
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 7491)
  AUTHORS   Luck,K., Kim,D.K., Lambourne,L., Spirohn,K., Begg,B.E., Bian,W.,
            Brignall,R., Cafarelli,T., Campos-Laborie,F.J., Charloteaux,B.,
            Choi,D., Cote,A.G., Daley,M., Deimling,S., Desbuleux,A., Dricot,A.,
            Gebbia,M., Hardy,M.F., Kishore,N., Knapp,J.J., Kovacs,I.A.,
            Lemmens,I., Mee,M.W., Mellor,J.C., Pollis,C., Pons,C.,
            Richardson,A.D., Schlabach,S., Teeking,B., Yadav,A., Babor,M.,
            Balcha,D., Basha,O., Bowman-Colin,C., Chin,S.F., Choi,S.G.,
            Colabella,C., Coppin,G., D'Amata,C., De Ridder,D., De Rouck,S.,
            Duran-Frigola,M., Ennajdaoui,H., Goebels,F., Goehring,L., Gopal,A.,
            Haddad,G., Hatchi,E., Helmy,M., Jacob,Y., Kassa,Y., Landini,S.,
            Li,R., van Lieshout,N., MacWilliams,A., Markey,D., Paulson,J.N.,
            Rangarajan,S., Rasla,J., Rayhan,A., Rolland,T., San-Miguel,A.,
            Shen,Y., Sheykhkarimli,D., Sheynkman,G.M., Simonovsky,E., Tasan,M.,
            Tejeda,A., Tropepe,V., Twizere,J.C., Wang,Y., Weatheritt,R.J.,
            Weile,J., Xia,Y., Yang,X., Yeger-Lotem,E., Zhong,Q., Aloy,P.,
            Bader,G.D., De Las Rivas,J., Gaudet,S., Hao,T., Rak,J.,
            Tavernier,J., Hill,D.E., Vidal,M., Roth,F.P. and Calderwood,M.A.
  TITLE     A reference map of the human binary protein interactome
  JOURNAL   Nature 580 (7803), 402-408 (2020)
   PUBMED   32296183
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL699477.1, BC152446.1, AC092296.2 and H17024.1.
            
            On Nov 22, 2018 this sequence version replaced NM_020917.2.
            
            Transcript Variant: This variant (2) uses an alternate splice site
            in the 5' coding region, compared to variant 1. It encodes isoform
            2, which is shorter by an amino acid, compared to isoform 1.
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC152446.1, AB046779.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA2149876, SAMEA2153031
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000270001.12/ ENSP00000270001.6
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-25                AL699477.1         4-28
            26-3351             BC152446.1         1-3326
            3352-7426           AC092296.2         23552-27626         c
            7427-7491           H17024.1           10-74               c
FEATURES             Location/Qualifiers
     source          1..7491
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="19"
                     /map="19q13.12"
     gene            1..7491
                     /gene="ZFP14"
                     /gene_synonym="ZNF531"
                     /note="ZFP14 zinc finger protein"
                     /db_xref="GeneID:57677"
                     /db_xref="HGNC:HGNC:29312"
                     /db_xref="MIM:620163"
     exon            1..39
                     /gene="ZFP14"
                     /gene_synonym="ZNF531"
                     /inference="alignment:Splign:2.1.0"
     exon            40..127
                     /gene="ZFP14"
                     /gene_synonym="ZNF531"
                     /inference="alignment:Splign:2.1.0"
     CDS             119..1720
                     /gene="ZFP14"
                     /gene_synonym="ZNF531"
                     /note="isoform 2 is encoded by transcript variant 2; zinc
                     finger protein 531; zinc finger protein 14 homolog"
                     /codon_start=1
                     /product="zinc finger protein 14 homolog isoform 2"
                     /protein_id="NP_065968.1"
                     /db_xref="CCDS:CCDS33002.1"
                     /db_xref="GeneID:57677"
                     /db_xref="HGNC:HGNC:29312"
                     /db_xref="MIM:620163"
                     /translation="MAHGSVTFRDVAIDFSQEEWEFLDPAQRDLYRDVMWENYSNFIS
                     LGPSISKPDVITLLDEERKEPGMVVREGTRRYCPDLESRYRTNTLSPEKDIYEIYSFQ
                     WDIMERIKSYSLQGSIFRNDWECKSKIEGEKEQQEGYFGQVKITSEKMTTYKRHNFLT
                     EYQIVHNGEKVYECKECRKTFIRRSTLSQHLRIHTGEKPYKCKECGQAFRQRAHLIRH
                     HKLHTGEKPYECKECGKAFTVLQELTQHQRLHTGEKPYECKECGKAFRVHQQLARHQR
                     IHTGEKPYECKDCGKTFRQCTHLTRHQRLHTAEKLYECKECGKAFVCGPDLRVHQKIH
                     FGEKPYECKECGKAFRICQQLTVHQSIHTGEKPYECKECGKTFRLRQQLVRHQRIHTR
                     EKPYECMECWKTFSSYSQLISHQSIHIGERPYECEECGKAFRLLSQLTQHQSIHTGEK
                     PYECKECRKPFRLLSQLTQHQSIHTGEKPYECKECGKAFRLYSFLTQHQRIHTGEKPY
                     KCKECKKAFRQHSHLTQHQKIHNGI"
     exon            128..254
                     /gene="ZFP14"
                     /gene_synonym="ZNF531"
                     /inference="alignment:Splign:2.1.0"
     exon            255..353
                     /gene="ZFP14"
                     /gene_synonym="ZNF531"
                     /inference="alignment:Splign:2.1.0"
     exon            354..7491
                     /gene="ZFP14"
                     /gene_synonym="ZNF531"
                     /inference="alignment:Splign:2.1.0"
     regulatory      5108..5113
                     /regulatory_class="polyA_signal_sequence"
                     /gene="ZFP14"
                     /gene_synonym="ZNF531"
                     /note="hexamer: AATAAA"
     polyA_site      5135
                     /gene="ZFP14"
                     /gene_synonym="ZNF531"
                     /note="major polyA site"
     regulatory      7467..7472
                     /regulatory_class="polyA_signal_sequence"
                     /gene="ZFP14"
                     /gene_synonym="ZNF531"
                     /note="hexamer: AATAAA"
     polyA_site      7491
                     /gene="ZFP14"
                     /gene_synonym="ZNF531"
                     /note="major polyA site"
ORIGIN      
        1 agttctttcc ggcttcgctg ctggtgtcgg ctccgagagc tctggcttat caggactcca
       61 tagttctcca acagagaaat cttgaaaagg actgaccagt ttttgcagtt ctaaaaccat
      121 ggcccatggt tcagtgacat tcagggatgt ggccatagac ttctcacagg aagaatggga
      181 attcctggat cctgctcaga gggacttata tagggatgta atgtgggaga actacagcaa
      241 cttcatttca ctaggacctt ccatttctaa accagatgtg attaccttat tggatgaaga
      301 aaggaaggaa cctgggatgg ttgtgaggga agggacaaga agatactgcc ctgatttgga
      361 gtccagatac aggaccaata ctttatctcc agaaaaggac atttatgaaa tatattcatt
      421 tcagtgggat ataatggaaa gaattaaaag ctatagcctt cagggttcca tttttaggaa
      481 tgattgggaa tgcaaaagca agattgaggg ggaaaaggaa caacaagagg gatattttgg
      541 gcaagtgaaa attacctctg aaaaaatgac cacttacaaa aggcacaatt ttcttactga
      601 gtatcagatc gttcataatg gagaaaaggt gtatgagtgt aaggagtgta ggaagacctt
      661 tattcgtcgc tcaacactta gtcaacacct gagaattcat actggtgaga aaccttataa
      721 gtgtaaggaa tgtgggcagg cctttagaca gcgtgcacat cttattcgac atcacaaact
      781 tcacaccggt gagaaaccct atgaatgtaa ggagtgtggg aaggccttta cagtgctcca
      841 agaacttact caacatcaga gacttcatac gggtgaaaaa ccctatgaat gtaaggaatg
      901 tggaaaggcc tttagagtac atcagcaact ggctcgacat cagagaattc acactggtga
      961 gaaaccctat gaatgtaagg actgtggaaa gacctttaga cagtgtacac accttacacg
     1021 ccatcagaga cttcatactg ctgaaaagct ctatgaatgt aaggaatgtg ggaaagcctt
     1081 cgtatgtggt ccagacctta gagtacatca gaaaattcat tttggtgaga aaccctatga
     1141 atgtaaggag tgtggaaagg cttttagaat atgccaacaa cttactgttc atcagagtat
     1201 tcatactggt gagaaaccct acgaatgtaa ggaatgtggg aagactttta gattaagaca
     1261 acaactagtt cgccatcaga gaatacatac tcgtgagaaa ccctatgaat gtatggaatg
     1321 ttggaagacc tttagtagtt actcacagct tatttcacac cagagcattc atattggtga
     1381 gagaccctat gaatgtgaag agtgtggaaa ggcctttaga ctgctctcac aacttactca
     1441 gcatcaaagt attcacactg gtgagaaacc ttatgaatgt aaggaatgta gaaaaccttt
     1501 tagactgctc tcacaactta cccaacatca gagtattcac actggtgaga aaccttatga
     1561 atgtaaggaa tgtggtaagg cttttagact ttattcattt cttactcaac accagagaat
     1621 tcatactggt gagaagccct acaagtgtaa ggagtgtaag aaggccttta gacagcattc
     1681 acaccttact cagcatcaga agattcataa tggaatttaa tagaagaaag ccttcaaatg
     1741 tatatgatgt tacagaacat cagaaaattc atttttgaga aaatgtgttt catgctcaat
     1801 tccaagcata ataaatttta tattagagaa agaatatgtt gatttaaaag ccttccaaca
     1861 ccatttaaac atggtttatc ttcagcaaat tcctatgaga gaataatgta atgaatgtag
     1921 gaaaatcttt agccttatct gtcattatct ccctttctcc acttgattac cagtttgatt
     1981 tattggacaa gatactaagc ttctgtgcct cattttgctg acttgtaaaa tggtaataat
     2041 agtacttata tgtattagtt atttattgct gcgtaataaa ttaccacaga cttagtagca
     2101 taaaataaca tataattata tcttataatt tggatcagga gtataggcat gacttagttg
     2161 ggtcctctgc ttcagggtct cttgcaaggc tacagatttc agccagggct gaggtctcat
     2221 ctgaaggctc aactggggaa ggatccacat ccagactaac atagttgtta cccaatgtat
     2281 ttccgtgagg cctgttgcat tgagattctc agtttctagc tggctgttgg ctgaacgctg
     2341 actgcagctc ctggccacaa tagcctcatc aacatggctg cttgcttcat caaggcatgc
     2401 aagccaaaag ggaggacagt ctgctagcaa gatggaagtt accatcttgt gtaatctaat
     2461 catggaagta acattccctc accttctact ggtagaagta agttactagg atagtccaca
     2521 ctcaagagaa cgggatgata caagagtgtg aataagtcct ggagacagga ccactggggg
     2581 gcctgtttag agtcagcctg ccacactgtg gaataggatt gttgcaagga gtaagtagtt
     2641 aatacttgga ggaatcacag tcatatagca tgtattctgt aaatattatc tgtaattgtt
     2701 attattgtca ttagtattag tgaattcacg taaaaggaag atctgtagac ataataaatg
     2761 tagaaatgcc tcctgtcacc tctcagaaat tattaaacat aatttattct aggtaaaatt
     2821 tagattgtag tgaatgtagg aagttcttca gcacttgagc tgcattagaa atttcatgcc
     2881 aaaaatgaat ttcatgaatg tgaggtcact agtaatacag ctgttgaaga attagaggga
     2941 aataggaaat gattttccca taattccaga aagcaaaagg cttacaatcc ctgttgtctg
     3001 accacagttt aaaattaatt agaaactatc aaaaatgtgg cttaaaagaa attaaccacc
     3061 taggaattta atattgttgt gtatatttat gtgtgtgtat aaaactcctg tgggaaagaa
     3121 acaaaacatc attctataag tcagtatact tttggatgct caaaatgcca tatcttcaac
     3181 cagtaggagt tgtttcaagt tgagtttttg atgtgatccc accaataatt tgatagttta
     3241 cttgattgtg gctgcataat ttggtaacct atgaaagatg ctagagcacc aatgtataat
     3301 ttttttgaga cagggtgtca ctttgtcccc caggctggag tgcagtggta caagcacagt
     3361 tcactgtacc ctgttcctcc tgggctcaag tgattcttcc acctaaattt tttttttttt
     3421 tttagagaaa gggtctcact atgttgccca ggctggtctt gaacttctgg gctcaagtga
     3481 tcctccctcc ttggcctcca aaggtgctgg ggttacaggt atgagccacc acacccagcc
     3541 caactcatta ttcttgaaat caataaatca gaggaaaaat tgtcatttag tttccttttc
     3601 ccatgtgaac caaatttcag ggtcaccaga agttcatcaa attcaaatga atttggcctg
     3661 gcacaggggt cacacctgta atcccagcac tttgggagga caaggtgggt ggatcacttg
     3721 aggccaggag tttgagacca acctggttaa catggtgaaa ccctgtctgt actaaaaata
     3781 caaaatttag ccaggcatgg tggcacacac ctgtagtccc aggctgaggt gggaggatca
     3841 cttgaaccca agaggcagag tttgcagtga gctgagatcg tgccactgca ctccagcctg
     3901 ggtgacagag tgagaccctg tctcaaaaaa aaaatttgtt ttttgaatgg gtttttcttt
     3961 tttgaagaag tctaataaat ctagaaggaa ttagaggatt agaaaaatca ccattttcta
     4021 gaccttaatg gaataatggg tccagaaaac atgatcttca atgggtacta caactaatag
     4081 gtgaaatatt ttatagcgag atttttatgg tggatctatc aaactggcca cctctgaacc
     4141 ctttgatctg ttttaacctt aataaaaatg ggtctatcag acaacacact tcctgacgta
     4201 atgcaatagg aagtccacac caccatctac aaagccttat tgctggaata atgaactgaa
     4261 agcagacagg gactagatga acagtatatg gtcatccctt ggtatccatg gggaattggt
     4321 tccaggatcc tccactgatg gtaaaatctg aggatgctca agtcccttgt ataaaatggc
     4381 atagtatgta tttgcatatt acctactcac atcttcctgt atactttaaa ttatctttag
     4441 atcacttata cctatcacaa tgtaaatact atgtaaatag ttgttatact gtatttttca
     4501 atttgcatta tttttattgt attttatttt tattgttttt ttttgagtat tttctatttg
     4561 agattggttg aatctgcaca tatggagggc tggctataaa gggcaccaca aggaagaagc
     4621 caaacagatc cagaatgtgt gaaattctac agagcaaatt acctgatttc ttcaactaac
     4681 aggtagcatg aaaatacaag gggaagggca accattaaca gattaaaaga gacttaaaga
     4741 gacatatcaa ctaaattcag tatgttggca ttacttggac ctggtttgaa caaaacataa
     4801 aaagccattt tggagacagt gagggaagtg tggacatgga ctaaatatta aatgatattt
     4861 acatatatta atttggttag ggattatgtc agtgtgatta taaaaaataa aagatcgtat
     4921 gatatgagat acatactatg aaatgaagat agacacattt ggattaaaat attctagcaa
     4981 aagaaataat tggcaaagag agctggaaac taaattggca acatgttgat aatttaagtg
     5041 gagtgttttg ttcatggaga cttattgttc taatatttct acttttgtat gtgtttgaaa
     5101 tttcaataat aaaatgttta aaatcaaaac caaaattata gactatgtag aaatgaatga
     5161 cagtgagatg cctgcacatc taaccttgtc agatataatc aaagttctgt tcagtgacaa
     5221 attaatgccc tgtaatgtgg taaggaaatc ttatttgtgg atacagtctt catcttcttc
     5281 acttacccac agcagcaaca ccaggcctgt cacacagatg aatgtgttga gggaatgaat
     5341 aagtatttcc gtcaagaaaa aggaaacaac aaaataaaac caacccaagt aaagaacagc
     5401 caagtggcca ggtgcggtgg ctcatgcctg taatcccagc actttgggag gccatggcag
     5461 gtggatcacc tgaggtcggg attttgagac cagcctgacc aacactgaga aaccccatct
     5521 ctattaaaga tacaaaatta gccaggcatg gtggtgcatg cctgtaatcc cagctacttg
     5581 ggaggctaag gcaggagaat cacttgaatc caggaggcgg agtttgtggt gagttgagat
     5641 cgcgccactg cactccagcc tgggtaacag agcaagagtc tgtcaaaaaa aaaaaaaaaa
     5701 aaaaaggaac agccaagtaa cagtagaaag tagaaattaa gagaatggag aatattagac
     5761 ttgattcaat gttaatagtg attagatttt ggcagttata atcaaggaag agaaaatgaa
     5821 agataataca tttagagtat taatgatgat aaaagagaca caactctaga ttatatcaag
     5881 cagattttta aaattataag gcaaaactag gccgggcaca gtggctcaca cctgtaaccc
     5941 cagcactttg ggaggccgag gtgggtggat cacttgaagt caggagttcg agaccagcct
     6001 gaccaacata gcaaaacccc atctctacta aaaatacaaa aattagcctg tcatggtggc
     6061 gggcacctgt aatctaagct actggggagc ctgaggcagg agaattgctt gaacccagga
     6121 ggcagaggtt gcggtgaacc aagatcacgc cactgcactc cagcctgggt gacagagtga
     6181 gaacctgtct caaaaataat aaacataata tggtaaaact atacatgcac acatgcacaa
     6241 acgtgtatat tcattccagt acaagtaaaa atgtaggatt gcatttttcc cccaaaagga
     6301 atatgtttta caattaactc accgtataac ccaaatagat taacaaaaaa tgtgtgtgtg
     6361 tgtgtgtgtg tgtgaactcc ctgtttaaaa aatctgatac ttataaaaac tttaaggaat
     6421 agataatcct aaagatttta ccaattaatt ctgcaaggta aaataatcct aataaaaatt
     6481 agatgaagat agtttctgaa agcaaattct agaccacctt cattatgaag attctatttt
     6541 tcacaattct aaataaagtt tatttagaat ttattacaaa atctatcttt gctaataggt
     6601 cagtgtttct tttcccaagc accaaatacc tccagaaagc ctgtgtttga cccctaaatt
     6661 caacattctc cagaagtttg cttcaaggaa tattaattct cgatggtatt tgaaaaaaag
     6721 atttcttggg aaaataggca aatgaagcaa aacataaaac atctactttt ggccaggcac
     6781 ggtggctcac gcctgtaatc ccaacatttt gggaggccaa ggcgagcaga tcacttgagg
     6841 tcaggagttt gagaccagcc tggccaacat ggtgaaaccc tgtctctact aaaaatacaa
     6901 aattagctgg gcgtggtggc ttgcacctgt aatcccagct acttgggagg ctgaggcagg
     6961 agaattgctt gaacccagga aatggagatt gcagtgagct gagattttgc cattgcactc
     7021 caacctgggc aacaagagtg aaactcagtc tcaaataaaa taaaataaaa atctactttt
     7081 gaggaattca aagtatacat gatcagtttg ccaaagattt agtaaagaca tttttattta
     7141 actgagtgta tctcaaattt attgtggaat tctcagtccg aatatctgga ataggaacag
     7201 ctttgttaga tgctaccata accacaatga atgtcttcaa gggtgtaatt ttagatatgg
     7261 tgagtggttg tgttgggggc ggcataagtc agggcaattt tttgcagctc atatcatgct
     7321 ctgaaagtag ctacctgctt taatggatgg ttagtgcttt tctatagaat ggaaaagatt
     7381 ccagcccgat ccttgatatg tttgtgttaa acatgcttat atattatatt aaacaatgat
     7441 taaggacata aatgagtttc tgtggtaata aagatgctat attgaatatc a
//
