LOCUS       NM_006885              15817 bp    mRNA    linear   PRI 16-DEC-2024
DEFINITION  Homo sapiens zinc finger homeobox 3 (ZFHX3), transcript variant A,
            mRNA.
ACCESSION   NM_006885
VERSION     NM_006885.4
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 15817)
  AUTHORS   Paucar,M., Nilsson,D., Engvall,M., Laffita-Mesa,J., Soderhall,C.,
            Skorpil,M., Halldin,C., Fazio,P., Lagerstedt-Robinson,K.,
            Solders,G., Angeria,M., Varrone,A., Risling,M., Jiao,H.,
            Nennesmo,I., Wedell,A. and Svenningsson,P.
  TITLE     Spinocerebellar ataxia type 4 is caused by a GGC expansion in the
            ZFHX3 gene and is associated with prominent dysautonomia and motor
            neuron signs
  JOURNAL   J Intern Med 296 (3), 234-248 (2024)
   PUBMED   38973251
  REMARK    GeneRIF: Spinocerebellar ataxia type 4 is caused by a GGC expansion
            in the ZFHX3 gene and is associated with prominent dysautonomia and
            motor neuron signs.
REFERENCE   2  (bases 1 to 15817)
  AUTHORS   He,M.F., Liu,L.H., Luo,S., Wang,J., Guo,J.J., Wang,P.Y., Zhai,Q.X.,
            He,S.L., Zou,D.F., Liu,X.R., Li,B.M., Ma,H.Y., Qiao,J.D., Zhou,P.,
            He,N., Yi,Y.H. and Liao,W.P.
  TITLE     ZFHX3 variants cause childhood partial epilepsy and infantile
            spasms with favourable outcomes
  JOURNAL   J Med Genet 61 (7), 652-660 (2024)
   PUBMED   38508705
  REMARK    GeneRIF: ZFHX3 variants cause childhood partial epilepsy and
            infantile spasms with favourable outcomes.
            Publication Status: Online-Only
REFERENCE   3  (bases 1 to 15817)
  AUTHORS   Perez Baca,M.D.R., Jacobs,E.Z., Vantomme,L., Leblanc,P.,
            Bogaert,E., Dheedene,A., De Cock,L., Haghshenas,S., Foroutan,A.,
            Levy,M.A., Kerkhof,J., McConkey,H., Chen,C.A., Batzir,N.A.,
            Wang,X., Palomares,M., Carels,M., Dermaut,B., Sadikovic,B.,
            Menten,B., Yuan,B., Vergult,S. and Callewaert,B.
  CONSRTM   ZFHX3 consortium
  TITLE     Haploinsufficiency of ZFHX3, encoding a key player in neuronal
            development, causes syndromic intellectual disability
  JOURNAL   Am J Hum Genet 111 (3), 509-528 (2024)
   PUBMED   38412861
  REMARK    GeneRIF: Haploinsufficiency of ZFHX3, encoding a key player in
            neuronal development, causes syndromic intellectual disability.
REFERENCE   4  (bases 1 to 15817)
  AUTHORS   Casalino-Matsuda,S.M., Chen,F., Gonzalez-Gonzalez,F.J., Matsuda,H.,
            Nair,A., Abdala-Valencia,H., Budinger,G.R.S., Dong,J.T.,
            Beitel,G.J. and Sporn,P.H.
  TITLE     Myeloid Zfhx3 deficiency protects against hypercapnia-induced
            suppression of host defense against influenza A virus
  JOURNAL   JCI Insight 9 (4), e170316 (2024)
   PUBMED   38227369
  REMARK    GeneRIF: Myeloid Zfhx3 deficiency protects against
            hypercapnia-induced suppression of host defense against influenza A
            virus.
            Publication Status: Online-Only
REFERENCE   5  (bases 1 to 15817)
  AUTHORS   Bedford,M.T., Chan,D.C. and Leder,P.
  TITLE     FBP WW domains and the Abl SH3 domain bind to a specific class of
            proline-rich ligands
  JOURNAL   EMBO J 16 (9), 2376-2383 (1997)
   PUBMED   9171351
REFERENCE   6  (bases 1 to 15817)
  AUTHORS   Miura,Y., Tam,T., Ido,A., Morinaga,T., Miki,T., Hashimoto,T. and
            Tamaoki,T.
  TITLE     Cloning and characterization of an ATBF1 isoform that expresses in
            a neuronal differentiation-dependent manner
  JOURNAL   J Biol Chem 270 (45), 26840-26848 (1995)
   PUBMED   7592926
REFERENCE   7  (bases 1 to 15817)
  AUTHORS   Yamada,K., Miura,Y., Scheidl,T., Yoshida,M.C. and Tamaoki,T.
  TITLE     Assignment of the human ATBF1 transcription factor gene to
            chromosome 16q22.3-q23.1
  JOURNAL   Genomics 29 (2), 552-553 (1995)
   PUBMED   8666409
REFERENCE   8  (bases 1 to 15817)
  AUTHORS   Yasuda,H., Mizuno,A., Tamaoki,T. and Morinaga,T.
  TITLE     ATBF1, a multiple-homeodomain zinc finger protein, selectively
            down-regulates AT-rich elements of the human alpha-fetoprotein gene
  JOURNAL   Mol Cell Biol 14 (2), 1395-1401 (1994)
   PUBMED   7507206
REFERENCE   9  (bases 1 to 15817)
  AUTHORS   Puschmann,A., Dobloug,S., Wallenius,J., Wictorin,K. and Gorcenco,S.
  TITLE     Spinocerebellar Ataxia Type 4
  JOURNAL   (in) Adam MP, Feldman J, Mirzaa GM, Pagon RA, Wallace SE and
            Amemiya A (Eds.);
            GENEREVIEWS(R);
            (1993)
   PUBMED   39666847
REFERENCE   10 (bases 1 to 15817)
  AUTHORS   Morinaga,T., Yasuda,H., Hashimoto,T., Higashio,K. and Tamaoki,T.
  TITLE     A human alpha-fetoprotein enhancer-binding protein, ATBF1, contains
            four homeodomains and seventeen zinc fingers
  JOURNAL   Mol Cell Biol 11 (12), 6041-6049 (1991)
   PUBMED   1719379
COMMENT     REVIEWED REFSEQ: This record has been curated by NCBI staff. The
            reference sequence was derived from AC002044.1, AC132068.2,
            BC029653.1 and AC004943.2.
            This sequence is a reference standard in the RefSeqGene project.
            
            On Nov 23, 2018 this sequence version replaced NM_006885.3.
            
            Summary: This gene encodes a transcription factor with multiple
            homeodomains and zinc finger motifs, and regulates myogenic and
            neuronal differentiation. The encoded protein suppresses expression
            of the alpha-fetoprotein gene by binding to an AT-rich enhancer
            motif. The protein has also been shown to negatively regulate
            c-Myb, and transactivate the cell cycle inhibitor cyclin-dependent
            kinase inhibitor 1A (also known as p21CIP1). This gene is reported
            to function as a tumor suppressor in several cancers, and sequence
            variants of this gene are also associated with atrial fibrillation.
            Multiple transcript variants expressed from alternate promoters and
            encoding different isoforms have been found for this gene.
            [provided by RefSeq, Sep 2009].
            
            Transcript Variant: This variant (A) encodes the longer isoform
            (A). Variants A and D both encode the same isoform (A. Expression
            of this variant is activated during neuronal differentiation.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: L32832.1, SRR14038193.4017837.1
                                           [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA1965299,
                                           SAMEA1966682 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000268489.10/ ENSP00000268489.5
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-377               AC002044.1         46370-46746
            378-3145            AC132068.2         42419-45186
            3146-4864           BC029653.1         370-2088
            4865-9853           AC004943.2         68238-73226
            9854-15817          AC004943.2         77633-83596
FEATURES             Location/Qualifiers
     source          1..15817
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="16"
                     /map="16q22.2-q22.3"
     gene            1..15817
                     /gene="ZFHX3"
                     /gene_synonym="ATBF1; ATBT; ATFB8; C16orf47; SCA4; ZFH-3;
                     ZNF927"
                     /note="zinc finger homeobox 3"
                     /db_xref="GeneID:463"
                     /db_xref="HGNC:HGNC:777"
                     /db_xref="MIM:104155"
     exon            1..377
                     /gene="ZFHX3"
                     /gene_synonym="ATBF1; ATBT; ATFB8; C16orf47; SCA4; ZFH-3;
                     ZNF927"
                     /inference="alignment:Splign:2.1.0"
     exon            378..3145
                     /gene="ZFHX3"
                     /gene_synonym="ATBF1; ATBT; ATFB8; C16orf47; SCA4; ZFH-3;
                     ZNF927"
                     /inference="alignment:Splign:2.1.0"
     CDS             427..11538
                     /gene="ZFHX3"
                     /gene_synonym="ATBF1; ATBT; ATFB8; C16orf47; SCA4; ZFH-3;
                     ZNF927"
                     /note="isoform A is encoded by transcript variant A; AT
                     motif-binding factor 1; AT-binding transcription factor 1;
                     zinc finger homeobox protein 3; alpha-fetoprotein enhancer
                     binding protein; zinc finger homeodomain protein 3"
                     /codon_start=1
                     /product="zinc finger homeobox protein 3 isoform A"
                     /protein_id="NP_008816.3"
                     /db_xref="CCDS:CCDS10908.1"
                     /db_xref="GeneID:463"
                     /db_xref="HGNC:HGNC:777"
                     /db_xref="MIM:104155"
                     /translation="MEGCDSPVVSGKDNGCGIPQHQQWTELNSTHLPDKPSSMEQSTG
                     ESHGPLDSLRAPFNERLAESTASAGPPSEPASKEVTCNECSASFASLQTYMEHHCPSA
                     RPPPPLREESASDTGEEGDEESDVENLAGEIVYQPDGSAYIVESLSQLTQGGGACGSG
                     SGSGPLPSLFLNSLPGAGGKQGDPSCAAPVYPQIINTFHIASSFGKWFEGPDQAFPNT
                     SALAGLSPVLHSFRVFDVRHKSNKDYLNSDGSAKSSCVSKDVPNNVDLSKFDGFVLYG
                     KRKPILMCFLCKLSFGYVRSFVTHAVHDHRMTLSEDERKILSNKNISAIIQGIGKDKE
                     PLVSFLEPKNKNFQHPLVSTANLIGPGHSFYGKFSGIRMEGEEALPAGSAAGPEQPQA
                     GLLTPSTLLNLGGLTSSVLKTPITSVPLGPLASSPTKSSEGKDSGAAEGEKQEVGDGD
                     CFSEKVEPAEEEAEEEEEEEEAEEEEEEEEEEEEEEEDEGCKGLFPSELDEELEDRPH
                     EEPGAAAGSSSKKDLALSNQSISNSPLMPNVLQTLSRGTASTSSNSASSFVVFDGANR
                     RNRLSFNSEGVRANVAEGGRRLDFADESANKDNATAPEPNESTEGDDGGFVPHHQHAG
                     SLCELGVGECPSGSGVECPKCDTVLGSSRSLGGHMTMMHSRNSCKTLKCPKCNWHYKY
                     QQTLEAHMKEKHPEPGGSCVYCKSGQPHPRLARGESYTCGYKPFRCEVCNYSTTTKGN
                     LSIHMQSDKHLNNMQNLQNGGGEQVFSHTAGAAAAAVAAAAAAANISSSCGAPSPTKP
                     KTKPTWRCEVCDYETNVARNLRIHMTSEKHMHNMMLLQQNMTQIQHNRHLGLGSLPSP
                     AEAELYQYYLAQNMNLPNLKMDSAASDAQFMMSGFQLDPAGPMAAMTPALVGGEIPLD
                     MRLGGGQLVSEELMNLGESFIQTNDPSLKLFQCAVCNKFTTDNLDMLGLHMNVERSLS
                     EDEWKAVMGDSYQCKLCRYNTQLKANFQLHCKTDKHVQKYQLVAHIKEGGKANEWRLK
                     CVAIGNPVHLKCNACDYYTNSLEKLRLHTVNSRHEASLKLYKHLQQHESGVEGESCYY
                     HCVLCNYSTKAKLNLIQHVRSMKHQRSESLRKLQRLQKGLPEEDEDLGQIFTIRRCPS
                     TDPEEAIEDVEGPSETAADPEELAKDQEGGASSSQAEKELTDSPATSKRISFPGSSES
                     PLSSKRPKTAEEIKPEQMYQCPYCKYSNADVNRLRVHAMTQHSVQPMLRCPLCQDMLN
                     NKIHLQLHLTHLHSVAPDCVEKLIMTVTTPEMVMPSSMFLPAAVPDRDGNSNLEEAGK
                     QPETSEDLGKNILPSASTEQSGDLKPSPADPGSVREDSGFICWKKGCNQVFKTSAALQ
                     THFNEVHAKRPQLPVSDRHVYKYRCNQCSLAFKTIEKLQLHSQYHVIRAATMCCLCQR
                     SFRTFQALKKHLETSHLELSEADIQQLYGGLLANGDLLAMGDPTLAEDHTIIVEEDKE
                     EESDLEDKQSPTGSDSGSVQEDSGSEPKRALPFRKGPNFTMEKFLDPSRPYKCTVCKE
                     SFTQKNILLVHYNSVSHLHKLKRALQESATGQPEPTSSPDNKPFKCNTCNVAYSQSST
                     LEIHMRSVLHQTKARAAKLEAASGSSNGTGNSSSISLSSSTPSPVSTSGSNTFTTSNP
                     SSAGIAPSSNLLSQVPTESVGMPPLGNPIGANIASPSEPKEANRKKLADMIASRQQQQ
                     QQQQQQQQQQQQQQQAQTLAQAQAQVQAHLQQELQQQAALIQSQLFNPTLLPHFPMTT
                     ETLLQLQQQQHLLFPFYIPSAEFQLNPEVSLPVTSGALTLTGTGPGLLEDLKAQVQVP
                     QQSHQQILPQQQQNQLSIAQSHSALLQPSQHPEKKNKLVIKEKEKESQRERDSAEGGE
                     GNTGPKETLPDALKAKEKKELAPGGGSEPSMLPPRIASDARGNATKALLENFGFELVI
                     QYNENKQKVQKKNGKTDQGENLEKLECDSCGKLFSNILILKSHQEHVHQNYFPFKQLE
                     RFAKQYRDHYDKLYPLRPQTPEPPPPPPPPPPPPLPAAPPQPASTPAIPASAPPITSP
                     TIAPAQPSVPLTQLSMPMELPIFSPLMMQTMPLQTLPAQLPPQLGPVEPLPADLAQLY
                     QHQLNPTLLQQQNKRPRTRITDDQLRVLRQYFDINNSPSEEQIKEMADKSGLPQKVIK
                     HWFRNTLFKERQRNKDSPYNFSNPPITSLEELKIDSRPPSPEPPKQEYWGSKRSSRTR
                     FTDYQLRVLQDFFDANAYPKDDEFEQLSNLLNLPTRVIVVWFQNARQKARKNYENQGE
                     GKDGERRELTNDRYIRTSNLNYQCKKCSLVFQRIFDLIKHQKKLCYKDEDEEGQDDSQ
                     NEDSMDAMEILTPTSSSCSTPMPSQAYSAPAPSANNTASSAFLQLTAEAEELATFNSK
                     TEAGDEKPKLAEAPSAQPNQTQEKQGQPKPELQQQEQPEQKTNTPQQKLPQLVSLPSL
                     PQPPPQAPPPQCPLPQSSPSPSQLSHLPLKPLHTSTPQQLANLPPQLIPYQCDQCKLA
                     FPSFEHWQEHQQLHFLSAQNQFIHPQFLDRSLDMPFMLFDPSNPLLASQLLSGAIPQI
                     PASSATSPSTPTSTMNTLKRKLEEKASASPGENDSGTGGEEPQRDKRLRTTITPEQLE
                     ILYQKYLLDSNPTRKMLDHIAHEVGLKKRVVQVWFQNTRARERKGQFRAVGPAQAHRR
                     CPFCRALFKAKTALEAHIRSRHWHEAKRAGYNLTLSAMLLDCDGGLQMKGDIFDGTSF
                     SHLPPSSSDGQGVPLSPVSKTMELSPRTLLSPSSIKVEGIEDFESPSMSSVNLNFDQT
                     KLDNDDCSSVNTAITDTTTGDEGNADNDSATGIATETKSSSAPNEGLTKAAMMAMSEY
                     EDRLSSGLVSPAPSFYSKEYDNEGTVDYSETSSLADPCSPSPGASGSAGKSGDSGDRP
                     GQKRFRTQMTNLQLKVLKSCFNDYRTPTMLECEVLGNDIGLPKRVVQVWFQNARAKEK
                     KSKLSMAKHFGINQTSYEGPKTECTLCGIKYSARLSVRDHIFSQQHISKVKDTIGSQL
                     DKEKEYFDPATVRQLMAQQELDRIKKANEVLGLAAQQQGMFDNTPLQALNLPTAYPAL
                     QGIPPVLLPGLNSPSLPGFTPSNTALTSPKPNLMGLPSTTVPSPGLPTSGLPNKPSSA
                     SLSSPTPAQATMAMGPQQPPQQQQQQQQPQVQQPPPPPAAQPPPTPQLPLQQQQQRKD
                     KDSEKVKEKEKAHKGKGEPLPVPKKEKGEAPTATAATISAPLPTMEYAVDPAQLQALQ
                     AALTSDPTALLTSQFLPYFVPGFSPYYAPQIPGALQSGYLQPMYGMEGLFPYSPALSQ
                     ALMGLSPGSLLQQYQQYQQSLQEAIQQQQQRQLQQQQQQKVQQQQPKASQTPVPPGAP
                     SPDKDPAKESPKPEEQKNTPREVSPLLPKLPEEPEAESKSADSLYDPFIVPKVQYKLV
                     CRKCQAGFSDEEAARSHLKSLCFFGQSVVNLQEMVLHVPTGGGGGGSGGGGGGGGGGG
                     GGGSYHCLACESALCGEEALSQHLESALHKHRTITRAARNAKEHPSLLPHSACFPDPS
                     TASTSQSAAHSNDSPPPPSAAAPSSASPHASRKSWPQVVSRASAAKPPSFPPLSSSST
                     VTSSSCSTSGVQPSMPTDDYSEESDTDLSQKSDGPASPVEGPKDPSCPKDSGLTSVGT
                     DTFRL"
     exon            3146..3642
                     /gene="ZFHX3"
                     /gene_synonym="ATBF1; ATBT; ATFB8; C16orf47; SCA4; ZFH-3;
                     ZNF927"
                     /inference="alignment:Splign:2.1.0"
     exon            3643..3874
                     /gene="ZFHX3"
                     /gene_synonym="ATBF1; ATBT; ATFB8; C16orf47; SCA4; ZFH-3;
                     ZNF927"
                     /inference="alignment:Splign:2.1.0"
     exon            3875..3955
                     /gene="ZFHX3"
                     /gene_synonym="ATBF1; ATBT; ATFB8; C16orf47; SCA4; ZFH-3;
                     ZNF927"
                     /inference="alignment:Splign:2.1.0"
     exon            3956..4089
                     /gene="ZFHX3"
                     /gene_synonym="ATBF1; ATBT; ATFB8; C16orf47; SCA4; ZFH-3;
                     ZNF927"
                     /inference="alignment:Splign:2.1.0"
     exon            4090..4290
                     /gene="ZFHX3"
                     /gene_synonym="ATBF1; ATBT; ATFB8; C16orf47; SCA4; ZFH-3;
                     ZNF927"
                     /inference="alignment:Splign:2.1.0"
     exon            4291..4393
                     /gene="ZFHX3"
                     /gene_synonym="ATBF1; ATBT; ATFB8; C16orf47; SCA4; ZFH-3;
                     ZNF927"
                     /inference="alignment:Splign:2.1.0"
     exon            4394..9853
                     /gene="ZFHX3"
                     /gene_synonym="ATBF1; ATBT; ATFB8; C16orf47; SCA4; ZFH-3;
                     ZNF927"
                     /inference="alignment:Splign:2.1.0"
     exon            9854..15817
                     /gene="ZFHX3"
                     /gene_synonym="ATBF1; ATBT; ATFB8; C16orf47; SCA4; ZFH-3;
                     ZNF927"
                     /inference="alignment:Splign:2.1.0"
     regulatory      15794..15799
                     /regulatory_class="polyA_signal_sequence"
                     /gene="ZFHX3"
                     /gene_synonym="ATBF1; ATBT; ATFB8; C16orf47; SCA4; ZFH-3;
                     ZNF927"
                     /note="hexamer: ATTAAA"
     polyA_site      15817
                     /gene="ZFHX3"
                     /gene_synonym="ATBF1; ATBT; ATFB8; C16orf47; SCA4; ZFH-3;
                     ZNF927"
                     /note="major polyA site"
ORIGIN      
        1 atttacataa agcgattccg ggcgggcggc ggcagaggag gaggcggcgg cggcgggcag
       61 gccggggacc cggacgccag cgccgcgccc cgtgggtgaa tccccgccgc gtcccgggga
      121 cctccctccg gggacgggcc gaccgccagc cctgccgcca ccatgagctc ccctcccctg
      181 tctccgggcc ccctgctcct gaccagagcc acctccgagt cctggggcca gcgggaggtg
      241 gggagcatgc cgcctggggt gggtgagctc ggggctcggg tgccactgga atttcccgtt
      301 gttgcgcatg gcggcgcggc ccccggacct gcaagtgccg cctccctccg gaggtgcgcg
      361 gaggcttggt gtgccaggtc cgagcctccg tactgggtgc aatgaaagct ccacgcaggc
      421 cttaccatgg aaggctgtga ctcgcccgtc gtctcgggga aggacaatgg gtgcggtatc
      481 cctcagcacc agcaatggac tgaactcaac agcacccacc tccctgacaa acccagtagc
      541 atggagcagt ccacaggcga gagccacggg cccttggaca gcctgagggc ccccttcaat
      601 gagcgcctcg cggagagcac cgcgtcggcc gggcccccct ccgagcccgc cagcaaggag
      661 gtcacctgca acgaatgttc ggcctccttt gccagcctcc agacctacat ggagcaccac
      721 tgccccagcg cgcgcccccc gccacccctg agagaggaga gcgccagcga caccggtgag
      781 gagggggacg aggagagtga cgtggagaac ctggccgggg agatcgtcta ccagccggac
      841 ggctccgcgt acattgtgga gagcctgagc cagctgaccc agggcggggg cgcctgtggg
      901 agtggcagtg gcagtgggcc tctcccctcg cttttcctga actctctccc tggcgcgggg
      961 ggcaagcaag gggacccttc gtgtgctgca cccgtgtacc cgcagatcat caacactttc
     1021 cacatagcct catccttcgg gaaatggttt gagggcccag accaggcttt cccgaatacc
     1081 tcagccctgg cggggctcag ccccgtcctg cacagcttcc gcgtgtttga cgtgcgacac
     1141 aaaagcaaca aggattacct gaacagcgac ggttctgcca aaagctcctg cgtatccaaa
     1201 gatgttccca acaatgtgga cctgtccaaa ttcgatggct ttgtgctcta tggcaagagg
     1261 aagcccatcc tgatgtgttt cttgtgcaaa ctctcctttg ggtacgtccg ttcgtttgtg
     1321 acccacgcgg tgcatgacca tcgaatgacc ctgagcgaag acgagcggaa aattcttagc
     1381 aataagaaca tctccgctat catccaaggg atcggcaaag acaaggaacc ccttgtaagt
     1441 tttctggaac caaaaaacaa aaactttcaa caccctttag tttccacagc taacctcata
     1501 ggccccggac acagttttta tggtaaattt agtggcattc gaatggaagg ggaggaagct
     1561 ctcccagcgg gctccgccgc tggccccgag cagccccagg ctggtctctt gacccccagc
     1621 accctgttga accttggcgg gctcaccagc tcggtactga agacccccat tacctcagtc
     1681 cccctggggc ctctggcttc cagtcctacc aaatcctcag agggcaagga ctctggggcg
     1741 gcagaaggag agaagcagga agtgggcgac ggggattgct tctctgagaa ggtagagcca
     1801 gccgaagagg aggcggagga ggaagaggag gaggaagagg cggaggagga ggaggaagaa
     1861 gaggaggagg aagaagagga ggaggaagac gagggttgca aaggactctt tccaagcgag
     1921 ttggatgagg aactggagga caggccccat gaggagcctg gggccgcagc aggtagtagc
     1981 agcaaaaagg accttgctct ctcaaaccaa agcatttcta actccccctt aatgcctaac
     2041 gtgctccaga ccctgtcgag gggcacagct tctactagtt ctaattctgc ttcttccttt
     2101 gttgtctttg atggtgcgaa caggaggaat cgtttaagct ttaacagtga gggcgtcagg
     2161 gccaatgtgg cagagggcgg caggaggctg gacttcgctg acgaaagtgc caataaagac
     2221 aatgccacag caccagaacc aaatgaaagc acagagggtg acgatggggg cttcgttccc
     2281 catcaccagc acgctggctc cctctgcgag cttggggttg gggagtgccc ctcggggagt
     2341 ggcgtggagt gccccaaatg cgacacggtc ctgggctcct cccgctcgct gggcggccac
     2401 atgaccatga tgcattctcg taactcgtgt aagacactca agtgccccaa gtgcaactgg
     2461 cactataagt accagcagac cctggaggca cacatgaagg agaagcaccc ggagccgggg
     2521 ggctcctgtg tctactgcaa aagcgggcag ccccaccccc ggctggcacg aggcgagagc
     2581 tacacgtgtg gttacaagcc tttccgctgc gaggtgtgta actactccac aactaccaaa
     2641 ggcaacctca gtattcatat gcagtctgac aagcatctca acaacatgca gaacctgcag
     2701 aatggagggg gggagcaggt cttcagccac actgccgggg cggcggcggc ggcggtggct
     2761 gcggcggcgg cggcagccaa tatcagtagc tcctgcgggg ccccctcgcc gaccaaacca
     2821 aaaaccaaac ccacctggcg gtgcgaggtg tgtgattatg agaccaacgt ggccaggaac
     2881 ctccgcattc acatgaccag tgagaagcac atgcataaca tgatgttact gcaacagaac
     2941 atgacccaga tccaacacaa ccgccacctg ggcctcggca gcctgccctc acccgccgag
     3001 gccgagctct accaatacta cctggcccag aacatgaacc tgcccaacct gaagatggac
     3061 agtgctgcct cggacgccca gttcatgatg agcggattcc agctggatcc cgccgggccc
     3121 atggccgcca tgacgcctgc tctagtgggc ggtgagatcc ccctagacat gcggctcggg
     3181 ggcgggcagc tggtgtcaga ggagctgatg aacctgggcg agagcttcat ccagaccaac
     3241 gacccgtcgc tgaagctctt ccagtgcgcc gtctgcaaca agttcacgac ggacaacctg
     3301 gacatgctgg gcctgcacat gaacgtggag cgcagcctgt cggaggacga gtggaaggcg
     3361 gtgatggggg actcatacca gtgcaagctc tgccgctaca acacccagct caaggccaac
     3421 ttccagctgc actgcaagac agacaagcac gtgcagaagt accagctggt ggcccacatc
     3481 aaggagggcg gcaaggccaa cgagtggagg ctcaagtgtg tggccatcgg caaccccgtg
     3541 cacctcaagt gcaacgcctg tgactactac accaacagcc tggagaagct gcggctgcac
     3601 acggtcaact ccaggcacga ggccagcctg aagttgtaca agcacctgca gcagcatgag
     3661 agtggtgtag aaggtgagag ctgctactac cactgcgttc tgtgcaacta ctccaccaag
     3721 gccaagctca acctcatcca gcatgtgcgc tccatgaagc accagcgaag cgagagcctg
     3781 cgaaagctgc agcggctgca gaagggcctt ccagaggagg acgaggacct ggggcagatc
     3841 ttcaccatcc gcaggtgccc ctccacggac ccagaagaag ccattgaaga tgttgaagga
     3901 cccagtgaaa cagctgctga tccagaggag cttgctaagg accaagaggg cggagcatcg
     3961 tccagccaag cagagaagga gctgacagat tctcctgcaa cctccaaacg catctccttc
     4021 ccaggtagct cagagtctcc cctctcttcg aagcgaccaa aaacagctga ggagatcaaa
     4081 ccggagcaga tgtaccagtg tccctactgc aagtacagta atgccgatgt caaccggctc
     4141 cgggtgcatg ccatgacgca gcactcggtg caacccatgc ttcgctgccc cctgtgccag
     4201 gacatgctca acaacaagat ccacctccag ctgcacctca cccacctcca cagcgtggca
     4261 cctgactgcg tggagaagct cattatgacg gtgaccaccc ctgagatggt gatgccaagc
     4321 agcatgttcc tcccagcagc tgttccagat cgagatggga attccaattt ggaagaggca
     4381 ggaaagcagc ctgaaacctc agaggatctg ggaaagaaca tcttgccatc cgcaagcaca
     4441 gagcaaagcg gagatttgaa accatcccct gctgacccag gctctgtgag agaagactca
     4501 ggcttcatct gctggaagaa ggggtgcaac caggttttca aaacttctgc tgcccttcag
     4561 acgcatttta atgaagtgca tgccaagagg cctcagctgc cggtgtcaga tcgccatgtg
     4621 tacaagtacc gctgtaatca gtgtagcctg gccttcaaga ccattgaaaa gttgcagctc
     4681 cattctcagt accatgtgat cagagctgcc accatgtgct gtctttgtca gcgcagtttc
     4741 cgaactttcc aggctctgaa gaagcacctt gagacaagcc acctggagct gagtgaggct
     4801 gacatccaac agctttatgg tggcctgctg gccaatgggg acctcctggc aatgggagac
     4861 cccactctgg cagaggacca taccataatt gttgaggaag acaaggagga agagagtgac
     4921 ttggaagata aacagagccc aacgggcagt gactctgggt cagtacaaga agactcgggc
     4981 tcagagccaa agagagctct gcctttcaga aaaggtccca attttactat ggaaaagttc
     5041 ctagaccctt ctcgccctta caagtgtacc gtctgcaagg aatctttcac tcaaaagaat
     5101 atcctgctag tacactacaa ttctgtctcc cacctgcata agttaaagag agcccttcaa
     5161 gaatcagcaa ccggtcagcc agaacccacc agcagcccag acaacaaacc ttttaagtgt
     5221 aacacttgta atgtggccta cagccagagt tccactctgg agatccatat gaggtctgtg
     5281 ttacatcaaa ccaaggcccg ggcagccaag ctggaggctg caagtggcag cagcaatggg
     5341 actgggaaca gcagcagtat ttccttgagc tcctccacgc caagtcctgt gagcaccagt
     5401 ggcagtaaca cctttaccac ctccaatcca agcagtgctg gcattgctcc aagctctaac
     5461 ttactaagcc aagtgcccac tgagagtgta gggatgccac ccctggggaa tcctattggt
     5521 gccaacattg cttccccttc agagcccaaa gaggccaatc ggaagaaact ggcagatatg
     5581 attgcatcca ggcagcagca acaacagcag cagcaacagc aacaacaaca acaacaacaa
     5641 caacaacaag cacaaacgct ggcccaggcc caggctcaag ttcaagctca cctgcagcag
     5701 gagctgcagc aacaggctgc cctgatccag tctcagctgt ttaaccccac cctccttcct
     5761 cacttcccca tgacaactga gaccctgctg caactacagc agcagcagca cctcctcttc
     5821 cctttctaca tccccagtgc tgagttccag cttaaccccg aggtgagctt gccagtgacc
     5881 agtggggcac tgacactgac tgggacaggc ccaggcctgc tggaagatct gaaggctcag
     5941 gttcaggtcc cacagcagag ccatcagcag atcttgccgc agcagcagca gaaccaactc
     6001 tctatagccc agagtcactc tgccctcctt cagccaagcc agcaccccga aaagaagaac
     6061 aaattggtca tcaaagaaaa ggaaaaagaa agccagagag agagggacag cgccgagggg
     6121 ggagagggca acaccggtcc gaaggaaaca ctgccagatg ccttgaaggc caaagagaag
     6181 aaagagttgg caccaggggg tggttctgag ccttccatgc tccctccacg cattgcttca
     6241 gatgccagag ggaacgccac caaggccctg ctggagaact ttggctttga gttggtcatc
     6301 cagtataatg agaacaagca gaaggtgcag aaaaagaatg ggaagactga ccagggagag
     6361 aacctggaaa agctcgagtg tgactcctgc ggcaagttgt tttccaacat cttgatttta
     6421 aagagtcatc aagagcacgt tcatcagaat tactttcctt tcaaacagct cgagaggttt
     6481 gccaaacagt acagagacca ctacgataaa ctgtacccac tgaggcccca gaccccagag
     6541 ccaccaccac ctccccctcc accccctcca cccccacttc cggcagcgcc gcctcagccg
     6601 gcgtccacac cagccatccc cgcatcagcc ccacccatca cctcacctac aattgcaccg
     6661 gcccagccat cagtgccgct cacccagctc tccatgccga tggagctgcc catcttctcg
     6721 ccgctgatga tgcagacgat gccgctgcag accttgccgg ctcagctacc cccgcagctg
     6781 ggacctgtgg agcctctgcc tgcggacctg gcccaactct accagcatca gctcaatcca
     6841 accctgctcc agcagcagaa caagaggcct cgcaccagga tcacagatga tcagctccga
     6901 gtcttgcggc aatattttga cattaacaac tcccccagtg aagagcaaat aaaagagatg
     6961 gcagacaagt ccgggttgcc ccagaaagtg atcaagcact ggttcaggaa cactctcttc
     7021 aaagagaggc agcgtaacaa ggactcccct tacaacttca gtaatcctcc tatcaccagc
     7081 ctggaggagc tcaagattga ctcccggccc ccttcgccgg aacctccaaa gcaggagtac
     7141 tggggaagca agaggtcttc aagaacaagg tttacggact accagctgag ggtcttacag
     7201 gacttcttcg atgccaatgc ttacccaaag gatgatgaat ttgagcaact ctctaattta
     7261 ctgaaccttc caacccgagt gatagtggtg tggtttcaga atgcccgaca gaaggccagg
     7321 aagaattatg agaatcaggg agagggcaaa gatggagagc ggcgtgagct tacaaatgat
     7381 agatacattc gaacaagcaa cttgaactac cagtgcaaaa aatgtagcct ggtgtttcag
     7441 cgcatctttg atctcatcaa gcaccagaag aagctgtgtt acaaggatga ggatgaggag
     7501 gggcaggacg acagccaaaa tgaggattcc atggatgcca tggaaatcct gacgcctacc
     7561 agctcatcct gcagtacccc gatgccctca caggcttaca gcgccccagc accatcagcc
     7621 aataatacag cttcctccgc tttcttgcag cttacagcgg aggctgagga actggccacc
     7681 ttcaattcaa aaacagaggc aggcgatgag aaaccaaagc tggcggaagc tcccagtgca
     7741 cagccaaacc aaacccaaga aaagcaagga caaccaaagc cagagctgca gcagcaagag
     7801 cagcccgagc agaagaccaa cactccccag cagaagctcc cccagctggt gtccctgcct
     7861 tcgttgccac agcctcctcc acaagcgccc cctccacagt gccccttacc ccagtcgagc
     7921 cccagtcctt cccagctctc ccacctgccc ctcaagcccc tccacacatc aactcctcaa
     7981 cagctcgcaa acctacctcc tcagctaatc ccctaccagt gtgaccagtg taagttggca
     8041 tttccgtcat ttgagcactg gcaggagcat cagcagctcc acttcctgag cgcgcagaac
     8101 cagttcatcc acccccagtt tttggacagg tccctggata tgcctttcat gctctttgat
     8161 cccagtaacc cactcctggc cagccagctg ctctctgggg ccatacctca gattccagca
     8221 agctcagcca cttctccttc aactccaacc tccacaatga acactctcaa gaggaagctg
     8281 gaggaaaagg ccagtgcaag ccctggcgaa aacgacagtg ggacaggagg agaagagcct
     8341 cagagagaca agcgtttgag aacaaccatc acaccggaac aactagaaat tctctaccag
     8401 aagtatctac tggattccaa tccgactcga aagatgttgg atcacattgc acacgaggtg
     8461 ggcttgaaga aacgtgtggt acaagtctgg tttcagaaca cccgagctcg ggaaaggaaa
     8521 ggacagttcc gggctgtagg cccagcgcag gcccacagga gatgcccttt ttgcagagcg
     8581 ctcttcaaag ccaagactgc tcttgaggct catatccggt cccgtcactg gcatgaagcc
     8641 aagagagctg gctacaacct aactctgtct gcgatgctct tagactgtga tgggggactc
     8701 cagatgaaag gagatatttt tgacggaact agcttttccc acctaccccc aagcagtagt
     8761 gatggtcagg gtgtccccct ctcacctgtg agtaaaacca tggaattgtc acccagaact
     8821 cttctaagcc cttcctccat taaggtggaa gggattgaag actttgaaag cccctccatg
     8881 tcctcagtta atctaaactt tgaccaaact aagctggaca acgatgactg ttcctctgtc
     8941 aacacagcaa tcacagatac cacaactgga gacgagggca acgcagataa cgacagtgca
     9001 acgggaatag caactgaaac caaatcctct tctgcaccca acgaagggtt gaccaaagcg
     9061 gccatgatgg caatgtctga gtatgaagat cggttgtcat ctggtctggt cagcccggcc
     9121 ccgagctttt atagcaagga atatgacaat gaaggtacag tggactacag tgaaacctca
     9181 agccttgcag atccctgctc cccgagtcct ggtgcgagtg gatctgcagg caaatctggt
     9241 gacagcggag atcggcctgg gcagaaacgt tttcgcactc aaatgaccaa tctgcagctg
     9301 aaggtcctca agtcatgctt taatgactac aggacaccca ctatgctaga atgtgaggtc
     9361 ctgggcaatg acattggact gccaaagaga gtcgttcagg tctggttcca gaatgcccgg
     9421 gcaaaagaaa agaagtccaa gttaagcatg gccaagcatt ttggtataaa ccaaacgagt
     9481 tatgagggac ccaaaacaga gtgcactttg tgtggcatca agtacagcgc tcggctgtct
     9541 gtacgtgacc atatcttttc ccaacagcat atctccaaag ttaaagacac cattggaagc
     9601 cagctggaca aggagaaaga atactttgac ccagccaccg tacgtcagtt gatggctcaa
     9661 caagagttgg accggattaa aaaggccaac gaggtccttg gactggcagc tcagcagcaa
     9721 gggatgtttg acaacacccc tcttcaggcc cttaaccttc ctacagcata tccagcgctc
     9781 cagggcattc ctcctgtgtt gctcccgggc ctcaacagcc cctccttgcc aggctttact
     9841 ccatccaaca cagctttaac gtctcctaag ccgaacttga tgggtctgcc cagcacaact
     9901 gttccttccc ctggcctccc cacttctgga ttaccaaata aaccgtcctc agcgtcgctg
     9961 agctccccaa ccccagcaca agccacgatg gcgatgggcc ctcagcaacc cccccagcag
    10021 cagcagcagc agcagcaacc acaggtgcag cagcctcccc cgccgccagc agcccagccg
    10081 ccacccacac cacagctccc actgcaacag cagcagcaac gcaaggacaa agacagtgag
    10141 aaagtaaagg agaaggaaaa ggcacacaaa gggaaagggg aacccctgcc tgtccccaag
    10201 aaggagaaag gagaggcccc cacggcaact gcagccacga tctcagcccc gctgcccacc
    10261 atggagtatg cggtagaccc tgcacagctg caggccctgc aggccgcgtt gacttcggac
    10321 cccacagcat tgctcacaag ccagttcctt ccttactttg taccaggctt ttctccttat
    10381 tatgctcccc agatccctgg cgccctgcag agcgggtacc tgcagcctat gtatggcatg
    10441 gaaggcctgt tcccctacag ccctgcactg tcgcaggccc tgatggggct gtccccaggc
    10501 tccctactgc agcagtacca gcaataccag cagagtctgc aggaggcaat tcagcagcag
    10561 cagcagcggc aactacagca gcagcagcag caaaaagtgc agcagcagca gcccaaagca
    10621 agccaaaccc cagtcccccc cggggctcct tccccagaca aagaccctgc caaagaatcc
    10681 cccaaaccag aagaacagaa aaacaccccc cgtgaggtgt cccccctcct gccgaaactc
    10741 cctgaagagc cagaagcaga aagcaaaagt gcggactccc tctacgaccc cttcattgtt
    10801 ccaaaggtgc agtacaagtt ggtctgccgc aagtgccagg cgggcttcag cgacgaggag
    10861 gcagcgagga gccacctgaa gtccctctgc ttcttcggcc agtctgtggt gaacctgcaa
    10921 gagatggtgc ttcacgtccc caccggcggc ggcggcggtg gcagtggcgg cggcggcggc
    10981 ggtggcggcg gcggcggcgg cggcggctcg taccactgcc tggcgtgcga gagcgcgctc
    11041 tgtggggagg aagctctgag tcaacatctc gagtcggcct tgcacaaaca cagaacaatc
    11101 acgagagcag caagaaacgc caaagagcac cctagtttat tacctcactc tgcctgcttc
    11161 cccgatccta gcaccgcatc tacctcgcag tctgccgctc actcaaacga cagcccccct
    11221 cccccgtcgg ccgccgcccc ctcctccgct tccccccacg cctccaggaa gtcttggccg
    11281 caagtggtct cccgggcttc ggcagcgaag cccccttctt ttcctcctct ctcctcatct
    11341 tcaacggtta cctcaagttc atgcagcacc tcaggggttc agccctcgat gccaacagac
    11401 gactattcgg aggagtctga cacggatctc agccaaaagt ccgacggacc ggcgagcccg
    11461 gtggagggtc ccaaagaccc cagctgcccc aaggacagtg gtctgaccag tgtaggaacg
    11521 gacaccttca gattgtaagc tttgaagatg aacaatacaa acaaatgaat ttaaatacaa
    11581 aaattaataa caaaccaatt tcaaaaatag actaactgca attccaaagc ttctaaccaa
    11641 aaaacaaaaa aaaaaaaaaa aagaaaaaaa agaaaaagcg tgggttgttt tcccatatac
    11701 ctatctatgc cggtgatttt acattcttgt ctttttcttt tcttttaata ttaaaaaaaa
    11761 aaaaaaagcc ctaaccctgt tacattgtgt ccttttgaag gtactattgg tctgggaaac
    11821 agaagtccgc agggcctccc taatgtcttt ggagcttaaa ccccttgtat atttgcccct
    11881 tttcaataaa cgccccacgc tgatagcaca gaggagcccg gcatgcactg tatgggaaag
    11941 cagtccacct tgttacagtt ttaaatttct tgctatctta gcattcagat accaatggct
    12001 tgctaaaaga aaaaaagaaa tgtaatgtct ttttattctc aggtcaatcg ctcacacttt
    12061 gttttcagaa tcattgtttt atatattatt gttttttcag tttttttttt tttttttgtt
    12121 ccagaaaaga ttttttgttt tgttaactta aaaatgggca gaaagtattc aagaaaaaca
    12181 atgtgaactg ctttagcttt ctggggattt ttaaggatag cttttctgct gaagccaatt
    12241 tcaaggggaa aagttaagca ctcccacttt caaaaaaaaa aaaaaataat aacccacaca
    12301 cacaaagagt gttgaggact tgtagcttaa aaaaaataag ttttaaaaac tgactttctg
    12361 tatttatgat agatatgacc atttttggtg ttgagtagat tgttgcattg gaaatgaact
    12421 gaagcagtat ggtagattta aaaggaaaaa aaaaaaaaaa ccttttgtgt acatttagct
    12481 ttttgtatgg tccagctgac agctcctcat ttgatgttgt cttgttcatt cctagcagat
    12541 gatagattgc aatccgttga ttcgcctaag cttttctccc cttgtccctt aattccactt
    12601 tctctttctt gtcccttaat tccactttct ctttccttct cccacctccc gtcctataat
    12661 ctcccactta aggtagctgc cttcatttct tagagggagc tgcagaatta ttttataaaa
    12721 ctaaagaaag aatttcaagg gattctaggg gtcattagga tcctcacaga ttatttttgg
    12781 ttggggagtt gaaacttttt aaaggcatat aattctagtt acctgtgtct gttagctttg
    12841 tgcatttatt ttttatttat ccttcttttg gctttttttt ctttgtaccc cttcttttcc
    12901 tccttgtttg gtaggagctt caaatattct ttttttttct atactaaagg atttgtttcc
    12961 atttgtgtaa ttggctgtgt acttttcttt tctaaaaaaa gtttttggtt agggatttgg
    13021 tttttggttt tgtgtttgtt ttttctttcc tctctcagaa aaaaaaattt catgctttaa
    13081 ataaaatcca aagacacacc ctttcactgc tgatgcagaa aaaagggaaa gggttcttgt
    13141 tacttgagaa tttgtttctg atttaaacaa acaagactta gtttaataaa agaaagagaa
    13201 aaacaaaaga ttcccaggtt gttatgtgct tcttctgcaa gcagagaggc aaatgttaat
    13261 gacaattcca tataccaaaa gacacatttt ttacttcaaa gttttgtcct tgtgttaggc
    13321 agtctgagca gcgagtgatc cagagcgcag ccaacaaagc agcagatagc agtgtacaga
    13381 aagcaaaaaa ggaactgtat gtgaggcact tgtttctgtt aatatccata ttcctgttaa
    13441 cacacaccct ttctcatgta aaaagaaaaa taaataaatg gtctgaactt tgaaaacttt
    13501 gtgctgctaa aacatagatt ttggagacaa ataaatagat gctttgctgt ttcactttca
    13561 tagctaaaca tcaacagaaa ccatctcccc ttgcccccaa agtgtgaaat ccttcttccc
    13621 ttcgttttct tccttatgtt tcaaaaggga actttgaaga ctgtgaatac aggttccatt
    13681 ggtcaccttt cgggcttctt tccccagtgc tgaagccact catcgacttt gcaaaagact
    13741 ggagcattcc aagatctgaa aatggatttt ttttcttttt ttctttttta gccgggacta
    13801 ttttattttt atgaatttgt ttttagttta atgaaatagt agatcctgaa atgttgtaca
    13861 tatttctaac taggctgatg cacagtgcaa attccttttt taattgtttt ttttaagtag
    13921 aaatactaaa gaaagaatac catctaacta ttcataccag tatccagttg tagcataagg
    13981 tgtcaaaagc aagtacgcaa aacatttact gttttaacaa gctatttcct tttaacaaga
    14041 aatcttgtat ttcttcctgt gtttgagatg aacattttta aattttaaag ttgtacagtt
    14101 ttttgttttc cattatttta tcttgtttgt aactctatga aatatatata tatatatttt
    14161 ttgccattta actgttgtat gttactctgt gtctgtacca tatagaaaaa aaattgtttt
    14221 tgtttttggt tctctatgtg atatcagtta acaatgtaac actagcttta cctgtcaaat
    14281 tctgctaggt cttctctgaa aacgttgttt ttaaaaatga tattgcttgg taatagtgca
    14341 atttctatcc ttttccctcc cccctcaact tttaagttct tttctttata attttgctgc
    14401 cccctccctg atggtttggg tttttgtttt tgtttttgtt tttttttttc atggagctac
    14461 tatgccatcc tccctctgtg aggcagagtg actgtcagtg ttttgttatg ccatgccttg
    14521 agctgtgggt gtttggcgac aataaggtgg ttgaatagat tggctgagca cacttccacc
    14581 cacctagtgt tctcagaggg gttatgtgat tgtttcaacc tggagtgggt tgcaccctta
    14641 atgctttcct ctgcaactaa accgcccaca tatatgttca ttgaaaaaag taagaataat
    14701 tctcagcact aacccagaag tagcaaagca gtcagtgatg gtgaacatta gaggtcaaac
    14761 atgagttaga tgtttgtggg ctgacagcca tcgtggctat gaccagtact atttacaaag
    14821 catgaattca ctacaatgct caactgtttg tttagcttta tctcacttgg ggaatttatt
    14881 cctgtctgct gcattgtagg tagctgggta ggatatattt ccacttgctt tttaaattag
    14941 ttcttcacct ccattgacac tcgttttttg gttttctccc tatagtgtgg gttggtgcta
    15001 gacaccagtc tgacccacag aatgggagtt atttcatcca tctttcctcc atccttccaa
    15061 aaaccacata tctacacaag gaaaaattta atacatctag gaattttttt tttaattaca
    15121 agctatttaa agagatgaat gtggccaaag ttttacacaa ttgaaaataa agtaaaacag
    15181 acggcatgtg tttaaacctg agtttatcag gcatggcagg aagttgcagg agagagaggc
    15241 agtgacccaa gccagtgcac ttgatgttca tggacatata ttttttttaa ataataaatt
    15301 aaaacatttt aaatagaagc ataaattgag ttgtttgttg gcgctgagat actgcccact
    15361 gtgaaacaaa gctttgacta gttttttgtt tgtttacttt cttcaggggg gaggggggca
    15421 agtttgggta ggaaagaaag cataaatgaa cgtgaccctg aggtgaagag gtatatgaac
    15481 agcctttgca atgtacaaaa agaaaaaaaa acaaaaaaca acaaaaaaaa tagagcaagt
    15541 gaaaccaaaa atgatgttct tggtgttttt ctataatgta gtcttgttag cttttttgtt
    15601 actgtaacaa tgctgatctc gaactgtacc aaaatacatg gagactaaca aacagaacca
    15661 catggaactt tcaaactgaa aaaaaaattt gtcacaaaaa ctttgttgtc atagttaagt
    15721 tgattgtaga tggtaattga atatactcct ttgaaaatat ttcatcaagt atgtttcctg
    15781 ctcattgtga tacattaaaa aaaaaatatg agcaaaa
//
