LOCUS       NM_020923              10285 bp    mRNA    linear   PRI 03-APR-2024
DEFINITION  Homo sapiens zinc finger DBF-type containing 2 (ZDBF2), transcript
            variant 1, mRNA.
ACCESSION   NM_020923 XM_371590 XM_937234
VERSION     NM_020923.3
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 10285)
  AUTHORS   Chacon-Camacho,O.F., Sobreira,N., You,J., Pina-Aguilar,R.E.,
            Villegas-Ruiz,V. and Zenteno,J.C.
  TITLE     Exome sequencing identifies a de novo frameshift mutation in the
            imprinted gene ZDBF2 in a sporadic patient with Nasopalpebral
            Lipoma-coloboma syndrome
  JOURNAL   Am J Med Genet A 170 (7), 1934-1937 (2016)
   PUBMED   27139419
  REMARK    GeneRIF: Exome sequencing identified a de novo heterozygous
            frameshift dinucleotide insertion c.6245_6246 insTT
            (p.His2082fs*67) in ZDBF2 (zinc finger, DBF-type containing 2), a
            gene located at 2q33.3. This variant was absent in parental DNA, in
            a set of 300 ethnically matched controls, and in public exome
            variant databases
REFERENCE   2  (bases 1 to 10285)
  AUTHORS   Kobayashi,H., Yanagisawa,E., Sakashita,A., Sugawara,N.,
            Kumakura,S., Ogawa,H., Akutsu,H., Hata,K., Nakabayashi,K. and
            Kono,T.
  TITLE     Epigenetic and transcriptional features of the novel human
            imprinted lncRNA GPR1AS suggest it is a functional ortholog to
            mouse Zdbf2linc
  JOURNAL   Epigenetics 8 (6), 635-645 (2013)
   PUBMED   23764515
REFERENCE   3  (bases 1 to 10285)
  AUTHORS   Kobayashi,H., Yamada,K., Morita,S., Hiura,H., Fukuda,A., Kagami,M.,
            Ogata,T., Hata,K., Sotomaru,Y. and Kono,T.
  TITLE     Identification of the mouse paternally expressed imprinted gene
            Zdbf2 on chromosome 1 and its imprinted human homolog ZDBF2 on
            chromosome 2
  JOURNAL   Genomics 93 (5), 461-472 (2009)
   PUBMED   19200453
  REMARK    GeneRIF: the human homolog (ZDBF2) of the mouse Zdbf2 gene showed
            paternal allele-specific expression in human lymphocytes but not in
            the human placenta.
COMMENT     REVIEWED REFSEQ: This record has been curated by NCBI staff. The
            reference sequence was derived from AB775781.1 and BQ021839.1.
            This sequence is a reference standard in the RefSeqGene project.
            
            On Nov 22, 2018 this sequence version replaced NM_020923.2.
            
            Summary: This gene encodes a protein containing DBF4-type zinc
            finger domains. This gene is imprinted and paternally expressed in
            lymphocytes but is more stochastically expressed in the placenta.
            Alternative splicing results in multiple transcript variants.
            [provided by RefSeq, Nov 2015].
            
            Transcript Variant: This variant (1) encodes the longer isoform
            (1).
            
            ##Evidence-Data-START##
            Transcript exon combination :: AB775781.1, AK127271.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA1968540, SAMEA1968968
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            imprinted gene         :: PMID: 19200453
            MANE Ensembl match     :: ENST00000374423.9/ ENSP00000363545.3
            RefSeq Select criteria :: based on longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-10282             AB775781.1         23-10304
            10283-10285         BQ021839.1         15-17               c
FEATURES             Location/Qualifiers
     source          1..10285
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="2"
                     /map="2q33.3"
     gene            1..10285
                     /gene="ZDBF2"
                     /gene_synonym="Slx9"
                     /note="zinc finger DBF-type containing 2"
                     /db_xref="GeneID:57683"
                     /db_xref="HGNC:HGNC:29313"
                     /db_xref="MIM:617059"
     exon            1..284
                     /gene="ZDBF2"
                     /gene_synonym="Slx9"
                     /inference="alignment:Splign:2.1.0"
     exon            285..337
                     /gene="ZDBF2"
                     /gene_synonym="Slx9"
                     /inference="alignment:Splign:2.1.0"
     exon            338..446
                     /gene="ZDBF2"
                     /gene_synonym="Slx9"
                     /inference="alignment:Splign:2.1.0"
     CDS             387..7451
                     /gene="ZDBF2"
                     /gene_synonym="Slx9"
                     /note="isoform 1 is encoded by transcript variant 1;
                     DBF4-type zinc finger-containing protein 2"
                     /codon_start=1
                     /product="DBF4-type zinc finger-containing protein 2
                     isoform 1"
                     /protein_id="NP_065974.1"
                     /db_xref="CCDS:CCDS46501.1"
                     /db_xref="GeneID:57683"
                     /db_xref="HGNC:HGNC:29313"
                     /db_xref="MIM:617059"
                     /translation="MQKRQGYCSYCRVQYNNLEQHLFSAQHRSLTRQSRRQICTSSLM
                     ERFLQDVLQHHPYHCQESSSTQDETHVNTGSSSEVVHLDDAFSEEEEEDEDKVEDEDA
                     TEERPSEVSEPIEELHSRPHKSQEGTQEVSVRPSVIQKLEKGQQQPLEFVHKIGASVR
                     KCNLVDIGQATNNRSNLVRPPVICNAPASCLPESSNDRPVTANTTSLPPAAHLDSVSK
                     CDPNKVEKYLEQPDGASRNPVPSSHVETTSFSYQKHKESNRKSLRMNSDKLVLWKDVK
                     SQGKTLSAGLKFHERMGTKGSLRVKSPSKLAVNPNKTDMPSNKGIFEDTIAKNHEEFF
                     SNMDCTQEEKHLVFNKTAFWEQKCSVSSEMKFDCISLQSASDQPQETAQDLSLWKEEQ
                     IDQEDNYESRGSEMSFDCSSSFHSLTDQSKVSAKEVNLSKEVRTDVQYKNNKSYVSKI
                     SSDCDDILHLVTNQSQMIVKEISLQNARHISLVDQSYESSSSETNFDCDASPQSTSDY
                     PQQSVTEVNLPKEVHIGLVDKNYGSSSSEVSADSVFPLQSVVDRPPVAVTETKLRKKA
                     HTSLVDNYGSSCSETSFDCDVSLESVVDHPQLTVKGRNLKGRQVHLKHKKRKPSSAKA
                     HLDCDVSLGTVADESQRAVEKINLLKEKNADLMDMNCESHGPEMGFQADAQLADQSQV
                     AEIERQKVDVDLENKSVQSSRSSLSSDSPASLYHSAHDEPQEALDEVNLKELNIDMEV
                     RSYDCSSSELTFDSDPPLLSVTEQSHLDAEGKERHIDLEDESCESDSSEITFDSDIPL
                     YSVIDQPEVAVYEEETVDLESKSNESCVSEITFDSDIPLHSGNDHPEVAVKEVIQKEE
                     YIHLERKNDEPSGSEISSDSHAPLHSVTNSPEVAVKKLNPQKEEQVHLENKENEPIDS
                     EVSLDYNIIFHSVTGRSEDPIKEISLHTKEHMYLENKSVFETSLDSDVPLQAATHKPE
                     VIVKETWLQREKHAEFQGRSTEFSGSKTSLDSGVPHYSVTEPQVAVNKINRKKQYVLE
                     NKNDKCSGSEIILDSNVPPQSMTDQPQLAFLKEKHVNLKDKNSKSGDSKITFDSEQLQ
                     EAVKKIDQWKEEVIGLKNKINEPSTYKLIHHPDVSVQSVADQPKVAIKHVNLGNENHM
                     YLEVKNSQYSCSEMNLDSGFLGQSIVNRPQITILEQEHIELEGKHNQCCGSEVSFDSD
                     DPLQSVADRLRETVKEISLWKDEEVDTEDRRNEAKGFEIMYDSDVLQPVAGQPEEVVK
                     EVSLWKEHVDLENKIVKPTDSRINFDSHEPLQSVTNKIPGANKEINLLREEHVCLDDK
                     GYVPSDSEIIYVSNIPLQSVIKQPHILEEEHASLEDKSSNSYSPEESSDSNDSFQAAA
                     DELQKPVKEINLWKEDHIYLEDKSYKLGDFDVSYASHIPVQFVTDQSSVPVKEINLQK
                     KDHNDLENKNCEVCGSEIKCHSCVHLQSEVDQPQVSYKEADLQKEEHVVMEEKTDQPS
                     DSEMMYDSDVPFQIVVNQFPGSVKETHLPKVVLVDLVPGDSDYEVISDDIPLQLVTDP
                     PQLTVKDISCINTECIDIEDKSCDFFGSEVRCNCKASTPSMTNQCKETFKIINRKKDY
                     IILGEPSCQSCGSEMNFNVDASDQSMTYESQGPDEKMVKYIDSEDKSCGYNGSKGKFN
                     LEDTSHRTTHRLQKAHKEASLRKDPRNAGLKGKSCQSSASAVDFGASSKSALHRRADK
                     KKRSKLKHRDLEVSCEPDGFEMNFQCAPPLPSDTDQPQETVKKRHPCKKVSSDLKEKN
                     HDSQSSSVLKVDSVRNLKKAKDVIEDNPDEPVLEALPHVPPSFVGKTWSQIMREDDIK
                     INALVKEFREGRFHCYFDDDCETKKVSSKGKKKVTWADLQGKEDTAPTQAVSESDDIV
                     CGISDIDDLSVALDKPCHRHPPAERPPKQKGRVASQCQTAKISHSTQTSCKNYPVMKR
                     KIIRQEEDPPKSKCSRLQDDRKTKKKVKIGTVEFPASCTKVLKPMQPKALVCVLSSLN
                     IKLKEGEGLPFPKMRHHSWDNDIRFICKYKRNIFDYYEPLIKQIVISPPLSVIVPEFE
                     RRNWVKIHFNRSNQNSSAGDNDADGQGSASAPLMAVPARYGFNSHQGTSDSSLFLEES
                     KVLHARELPKKRNFQLTFLNHDVVKISPKSVRNKLLESQSKKKIHGKRVTTSSNKLGF
                     PKKVYKPIILQQKPRKASEKQSIWIRTKPSDIIRKYISKYSVFLRHRYQSRSAFLGRY
                     LKKKKSVVSRLKKAKRTAKVLLNSSVPPAGAEELSSAMANPPPKRPVRASCRVARRRK
                     KTDESYHGRQKGPSTPVRAYDLRSSSCLQQRERMMTRLANKLRGNEVK"
     exon            447..574
                     /gene="ZDBF2"
                     /gene_synonym="Slx9"
                     /inference="alignment:Splign:2.1.0"
     exon            575..10285
                     /gene="ZDBF2"
                     /gene_synonym="Slx9"
                     /inference="alignment:Splign:2.1.0"
     regulatory      10272..10277
                     /regulatory_class="polyA_signal_sequence"
                     /gene="ZDBF2"
                     /gene_synonym="Slx9"
                     /note="hexamer: ATTAAA"
     polyA_site      10285
                     /gene="ZDBF2"
                     /gene_synonym="Slx9"
                     /note="major polyA site"
ORIGIN      
        1 aaacctccat cagggttgca acgccacgtt gccttggatg cctgcgtgag tggagtcgcg
       61 actcggggcc cgcgtcctga gagacgcgct cccgcgccgc ttctcgcctc cggaccgcag
      121 gggccgaagt cgcctatttc tggctccgcg ggcagcgggg ccgtggcgct cggacggtct
      181 gggattcggg cgccgccgcg gaaccggaat aagaagggag agcgcccggc tcggtcctcg
      241 gtctccaccg cggcccggaa ggaatccggg cagcctccgc ggagatactt gccagaacta
      301 atacagctga tgaaatacct gaccttttct gctccagctt gagtattcaa agacagtagc
      361 catctgactt cagttattta ttcaagatgc agaaaagaca aggatattgc agttattgcc
      421 gtgtgcagta taataacctg gaacagcatt tgttcagtgc tcagcacagg agtttgacca
      481 gacagagtag acgtcaaata tgtaccagta gtttgatgga acgtttctta caggatgtac
      541 tgcagcacca cccatatcat tgtcaagaga gcagttcaac acaagatgag acacatgtga
      601 atactgggtc atcgtctgaa gtggtgcatt tggatgatgc tttttctgaa gaagaggaag
      661 aggatgagga taaggttgag gatgaggatg ctaccgaaga gagaccatcc gaggtttcag
      721 aacctattga agagttacat tccagacctc ataaatctca ggaaggcacg caggaggttt
      781 cagttcgacc atcagttatt caaaaactgg agaagggaca gcagcagccc ttggagtttg
      841 ttcataaaat tggggccagt gtgagaaaat gtaacctagt agatattggt caggctacaa
      901 ataatagaag caacttggta cgccccccag tgatttgtaa tgctcctgct agttgtttac
      961 ctgaaagctc taacgataga ccagttacag ctaatacaac tagtttacca ccagcagctc
     1021 atttggattc agttagcaaa tgtgacccaa acaaagttga gaaatatctt gaacagccag
     1081 atggggcctc tagaaatcct gtgccatcat cccatgtaga aactacttca ttttcgtatc
     1141 agaaacataa agaatcaaat aggaaatctt tacgcatgaa ttcagataag ttggttttgt
     1201 ggaaagatgt aaaatctcag ggtaaaactt tatcagctgg cttgaaattc catgaacgca
     1261 tgggtactaa gggctcctta agagttaaat ctccttccaa attagcagta aacccgaata
     1321 aaactgacat gccttctaat aaaggaatct ttgaagatac tattgcaaag aaccatgagg
     1381 aattcttttc taacatggat tgtacccaag aagaaaagca tttggttttt aacaagacag
     1441 ccttttggga acagaagtgc tcagtgagtt ctgaaatgaa gtttgattgt atctctcttc
     1501 agtcagcatc tgatcagccc caagagactg cacaagactt aagtctttgg aaggaggagc
     1561 aaattgacca agaagataac tatgagtcta gaggttcaga aatgagtttt gattgcagtt
     1621 cctcttttca ttcactgact gaccaatcta aagtgagtgc caaagaagta aacctttcca
     1681 aggaagtacg tactgatgta cagtataaga ataataaatc ttatgtttct aaaataagtt
     1741 ctgattgtga tgacattctt cacttggtta ccaaccaatc ccaaatgatt gttaaagaaa
     1801 taagtcttca gaatgcaagg catattagcc tggttgacca aagctatgaa tctagtagtt
     1861 ctgaaacgaa ttttgattgt gatgcttcac ctcagtccac tagtgactac ccccaacaat
     1921 ctgtaacaga agtaaacctt cctaaggaag tgcacattgg tttggttgat aagaactatg
     1981 gttccagtag ctctgaagta agtgctgatt ctgttttccc actgcagtca gtggttgaca
     2041 gacccccagt ggctgtcaca gaaacaaaac ttcggaagaa ggctcatacc agcttggttg
     2101 ataactatgg atcgagttgt tctgaaacaa gttttgattg tgatgtttct cttgagtcag
     2161 tagttgatca tccccaactg actgtcaaag gaagaaacct gaaaggtaga caagtccacc
     2221 taaaacataa gaagcgtaaa cccagtagtg ctaaagcaca tcttgattgt gatgtctcac
     2281 ttgggacagt tgcagatgaa tcccagaggg ctgttgaaaa gataaatctt ctgaaggaga
     2341 agaatgctga ccttatggat atgaactgtg aatcccatgg tcctgaaatg ggttttcagg
     2401 ctgatgctca attagctgac cagtctcaag tagccgaaat agagcgtcag aaagtggatg
     2461 ttgaccttga gaataagagt gttcagtcta gccgttcttc tctgagttct gattctccgg
     2521 cttctcttta tcattcagct catgatgagc ctcaagaagc tttggatgaa gtaaatctta
     2581 aagagttaaa tattgacatg gaagttagga gctatgattg ctccagctct gagttgactt
     2641 ttgattctga cccgcctctt ctgtcagtta ctgagcagtc tcatctggat gctgaaggaa
     2701 aagaacggca cattgacctg gaagatgaga gctgtgagtc agatagttct gaaataactt
     2761 ttgattctga tattcctctt tattcagtaa ttgaccaacc tgaagtagct gtttatgagg
     2821 aagaaactgt tgatctggaa agtaaaagta atgaatcttg tgtctctgaa ataacttttg
     2881 attctgatat tcctcttcat tcaggaaatg atcaccctga agtagctgtt aaagaagtaa
     2941 ttcagaaaga agagtacatt cacttagaaa ggaagaatga tgaacccagt ggttctgaaa
     3001 taagttcgga ttcccatgcc cctcttcatt cagtgactaa ttctcccgaa gtagctgtta
     3061 aaaagctaaa tcctcaaaaa gaagagcagg tacacttaga aaataaggaa aatgaaccta
     3121 ttgattctga agtaagtttg gattataata tcatttttca ttcagtgact ggacgttctg
     3181 aagatcccat taaagaaata agccttcaca caaaagagca catgtactta gaaaataaga
     3241 gtgtttttga aacaagtttg gattctgatg tccctcttca ggcagcgact cacaaacctg
     3301 aagtaattgt caaagaaaca tggcttcaaa gagaaaagca cgctgaattc caaggtagaa
     3361 gtactgaatt cagtggttca aaaacaagtt tagattctgg tgtccctcat tattcagtaa
     3421 ctgaacctca agtagctgtt aacaaaataa acagaaagaa gcaatatgtt ctagaaaaca
     3481 agaatgataa atgtagtggt tctgaaataa ttttggattc taatgttcca cctcagtcaa
     3541 tgactgacca acctcaacta gcttttttga aggaaaaaca tgttaatctg aaggacaaaa
     3601 acagtaaatc aggtgattct aaaataactt ttgattctga acaacttcag gaagcggtta
     3661 aaaaaataga ccaatggaag gaagaggtta ttggcctgaa aaataagatt aatgaaccta
     3721 gtacttataa attaatacat catcctgatg tttctgtcca atctgtggct gatcaaccca
     3781 aagtagctat taaacatgtg aaccttggga atgaaaacca tatgtacttg gaagttaaga
     3841 acagccaata tagttgttca gaaatgaatt tggattctgg tttcttgggt cagtcaatag
     3901 tcaatcgacc tcaaataact attttggagc aggagcacat tgaactagaa ggtaagcaca
     3961 atcaatgttg tggttctgaa gtaagttttg attctgatga ccctcttcag tcagtggctg
     4021 accggctgag agaaaccgtt aaagaaataa gcctttggaa ggatgaagaa gttgacacgg
     4081 aagataggag aaatgaagct aagggttttg aaattatgta tgattctgat gttcttcagc
     4141 cagtggctgg ccaacctgaa gaagtagtta aggaggtcag tctttggaaa gagcatgttg
     4201 acttggaaaa taagattgtc aaacctacag attccagaat aaattttgat tctcatgaac
     4261 cccttcagtc cgtaactaat aaaattccag gggcgaataa agaaataaat cttttgaggg
     4321 aggaacatgt ttgtctggat gataagggct atgtgcccag tgattctgaa ataatttatg
     4381 tttcaaatat ccctcttcag tcagtgataa aacaaccaca cattttggaa gaggagcatg
     4441 ccagtctgga agataagagc agtaattctt atagtcctga agaaagttct gattccaatg
     4501 actcttttca ggcagcagca gatgagcttc aaaaacctgt caaagaaata aatctttgga
     4561 aggaagacca tatttacctg gaagataaga gctataaatt aggtgatttt gatgtaagtt
     4621 atgcttctca tattcctgtt cagtttgtga ctgatcaatc ttctgtacct gtcaaagaaa
     4681 taaacttgca aaagaaggat cataatgatc tagaaaataa gaactgtgaa gtctgtggtt
     4741 ctgaaataaa atgtcattct tgtgttcatc ttcagtcaga agttgaccaa cctcaagtgt
     4801 cttacaaaga ggcagacctt cagaaggaag agcatgttgt catggaagaa aagaccgatc
     4861 aacctagtga ttcagaaatg atgtatgatt ctgatgttcc ttttcaaata gtagttaacc
     4921 aatttccagg atcagtcaaa gaaacccacc ttccaaaggt ggtacttgtg gatctggtgc
     4981 ccggtgatag tgattatgaa gtaatttcag atgatattcc ccttcagtta gtgactgacc
     5041 cacctcagtt gactgtcaaa gatatcagct gtataaatac agaatgtatt gatatagaag
     5101 ataagagctg tgactttttt ggttctgaag tcagatgtaa ttgtaaagcc tctactccct
     5161 caatgacaaa ccaatgcaaa gagactttca aaataataaa ccggaagaag gactatatta
     5221 ttctgggaga gccaagttgt caatcttgtg gttctgaaat gaattttaat gttgatgcct
     5281 ctgatcagtc catgacttac gagtcacaag gacctgatga gaaaatggtg aaatatattg
     5341 attcagaaga taagagctgt ggatataatg gttctaaagg aaaatttaat ttggaagaca
     5401 cttctcatcg aacgactcac cgactgcaga aagctcacaa agaagccagt cttcggaagg
     5461 atccaagaaa tgctggccta aaaggtaaga gctgtcagtc tagtgcttct gcagtggatt
     5521 ttggtgcctc ttccaagtca gcgctccatc gaagggctga taaaaaaaaa cgttcgaagc
     5581 taaaacatag agatctagaa gtgagctgtg aaccggatgg ttttgagatg aattttcagt
     5641 gtgctccccc tcttccatct gatactgatc agcctcaaga aactgttaag aaaagacacc
     5701 cttgtaagaa ggtatcttct gacttgaaag aaaagaacca tgattcccag tcaagctctg
     5761 ttctcaaggt tgattctgta aggaacctga aaaaagcaaa ggatgtcata gaggataatc
     5821 ctgatgaacc agttcttgaa gccttgcctc atgtacctcc ttcatttgtg gggaaaacat
     5881 ggtctcagat aatgagagaa gatgacataa aaattaatgc tctggtgaag gagtttaggg
     5941 aaggtcgttt ccactgttac tttgatgatg actgtgagac caaaaaagtt tcttcgaagg
     6001 ggaaaaaaaa ggttacctgg gctgacttgc aaggtaagga ggacactgca ccaactcaag
     6061 ctgtgtcaga gagtgatgat attgtctgtg gtatttcaga tattgatgac ttgtcagtgg
     6121 ccttagataa accatgccat cgtcatcctc cagcagagag gcctcctaag caaaaggggc
     6181 gtgtggcttc tcaatgccag acagcgaaaa tcagccatag tactcagacc agttgtaaga
     6241 attacccagt gatgaaaaga aaaataatta gacaagagga agacccacca aaaagtaagt
     6301 gttcacgttt acaggatgac agaaaaacca aaaagaaagt caaaattggg acagttgaat
     6361 ttcctgcatc atgtactaaa gttttgaagc ctatgcaacc caaagcctta gtctgtgttc
     6421 tttcttcttt aaatattaaa ctgaaagagg gtgaaggcct tcctttccct aaaatgaggc
     6481 accatagttg ggataatgat attcggttta tatgcaaata taaacggaat atctttgatt
     6541 attatgagcc cttgattaag caaattgtaa ttagtcctcc cctgagtgta atagtaccag
     6601 agtttgagag gcgtaactgg gttaaaattc attttaatag gagcaaccaa aactccagtg
     6661 caggagataa tgatgctgat ggacaaggct ctgcttcagc gcctttaatg gcagtgccgg
     6721 caagatatgg atttaattca catcagggaa ccagtgactc ttctctgttt ctggaagaat
     6781 caaaggttct gcatgctcgt gagcttccaa agaaaagaaa tttccagcta acatttttaa
     6841 atcatgatgt tgtcaaaatc tctccaaaat cagttagaaa taagcttttg gaaagtcaaa
     6901 gtaaaaagaa aattcatgga aagagggtga caactagtag taataagcta ggttttccca
     6961 aaaaggttta taaaccaatt attctccagc aaaaacccag aaaagcttca gagaaacagt
     7021 caatttggat tcggaccaaa ccaagtgata tcattagaaa gtatatttcg aaatactctg
     7081 tctttttacg tcatagatat cagtccagga gcgcttttct tggaaggtat ctgaagaaga
     7141 aaaaatctgt tgtcagtagg ctaaagaagg cgaagagaac agctaaagtg cttttgaact
     7201 cttcagttcc accagctggt gccgaagagc tgtcaagcgc tatggcaaat cctcctccaa
     7261 agcgacctgt gcgggcttct tgccgcgttg caagaaggag gaagaagact gatgaaagct
     7321 accatggccg acagaaaggt ccttctacac ctgtgagagc atatgatctg agaagctcat
     7381 cttgtttaca acaacgtgag agaatgatga ctcggctagc aaacaaactg agaggtaatg
     7441 aggtaaaata gaagttggtt ttgtgttcag gctagttgag gattcagtac ttcagttgaa
     7501 atatatttgg tactttgtgc acacagcttt cccagctttg gtgagaaaac taatcttgaa
     7561 ctattttgct ataaatatta tttttcagaa tttttatatt catttaaaat tagtgtttag
     7621 agtcctttca ttttaagatt cagaaacagc ctttgtccaa cattttctgt agaagaactt
     7681 catcttaatt tatgtcacaa aataatttag caccgtatat agaattttgt tcctcaaatc
     7741 atatccctct tattttttat gattatctct ctcatgccag caaatttaac attgtgagaa
     7801 tgaatatagc aaacttatta aaaagaagga attataatga attatgtcaa cttttgaatg
     7861 gggttgactt aaatgaatac aaacaaaata taagttttct ttctttttaa agcattccag
     7921 aaaatgagat tccataatct ttaatacagt ttttaaaaac tggtgatttt ttttatgcat
     7981 agcacaaact cctcctgctt catttaaatt ggatctgcaa gtctctaact tttatcattt
     8041 ggacacatgc acacatacag tctctaggtt ttttgggtta gccttattag atcttaaagg
     8101 ggaaaataat tttgcccatg tgtttaggca ttccccccct tttttttaac cacctttact
     8161 ctcttctaca tgaagagttg gtggcttaat atgaaaatcc aggttatttt gtggccttat
     8221 cccctaaaaa tattttaggc attaccatat cagtttttat ttttatgttt atttattatt
     8281 attatttttt gagacagagt ctcactgtct tgcccaggct ggagtgcagt ggcctgaact
     8341 tagctcaccg caacctccac ctcccgggtt caagcaattc tcctgcctaa gcctctcgag
     8401 tagctgggac tacaggcgtg cgccaccatg cccggctaat ttttgtattt ttagtagagt
     8461 tgggggtttc actatgttgg ccaggctggt ctcaaactcc tgaccttgtg gtccacccgc
     8521 ctcagcctcc caaagtgctg ggattacagt catgagccac catgcccagc ctaccatatc
     8581 agtttttaat aacttgaact gaaattattg gcttggtaat atttgggcag gccattaatt
     8641 ctcattagaa aattacttaa tatttcaaaa aattgaataa aactggtaat ctttgtggag
     8701 gcccattttg caagtggaaa cctgtattta tacattagtt tgtctttaac tatttgttaa
     8761 cagattttaa cagttcaaat gaaagatgtt aacgagatgc agtttgagtc tgggatactc
     8821 agaatagatc cagaaccttt attcagggac actggttgag ttggtacaga tgcattcagt
     8881 tgtcattcat tcgtgttaag ccaagatcct ggatcttcta tcattaatgt taagaggaaa
     8941 catgaattac aactatattg tatgactgcc atattttatt gaaactaagg tcaatgttga
     9001 accatatctt gatttcagaa tttaaaatgt gttaccttag aaataatgaa atatagtgta
     9061 acagttggtt tctaaatgtg gttttatttc aggggccatt atttaacctg tgtgtatgct
     9121 atgatggagt tcttttgtga tttctttact tctaaattta aatagtaatt atgtttaaaa
     9181 acaaatgttt ttgtctttag ttgcaaagca gcatatatct catttccttc aaccttgcct
     9241 cctcatacac aaatatattt tcatttctta aaagatcact gggccagtag ttcaaaataa
     9301 tcctccaatt ttaatttagg aacaaagctt tgtcctactg actaggaagt aaacaaacag
     9361 ctgatatata agatatttgt gggtattggt gtcttttttc cctatggaat agacacatag
     9421 ttcccttaaa tattattaat agacattcta cagtctttca gtgtaagttt aaaagcaaga
     9481 gatcaaatga aaatgtgtac tatgtaccta tgatgtgtca tatcgtgatt acatcatgca
     9541 gagagaacag ttcctgtaat tcaagtaatt aaaatttcaa gttgtaaaaa tgttaccatt
     9601 ttcacattgg aagcccttct aagtaccatt ttcattgggg gcagggagaa ggtttatatt
     9661 taaattttat attaccagac ataaaagtac agtgcagtac tgatgatttt gtttaaagtt
     9721 tttgaaatgt tttgtttact aagttcttgt aatcattatt ttagacaagc ttgaaaactt
     9781 gaaattgttg aaacttataa tttaaattaa attggaaatt actttcagaa tttggtagta
     9841 tacaagatgt gcccctttgt ctaaataaat gttggcttaa tttgcagaat agataaaaca
     9901 attgatgttt ttgtgtgttc aagaatgcat taaattcttt taatagtaaa aagtcaaatt
     9961 acgaccataa tgagtatttt aatcttgttc ttgttcagta ttttgcgtag atttttattg
    10021 taattgtcct gagttctaca gtatgtgaac aatatcgtgt gaagtgtgtt tttgcatttg
    10081 tgcatttaaa ttatttatgt aactagggct gtgagtaaca cttttttttt ttttttttgg
    10141 ttaaagaaaa gctatattta aatattcaaa taattatata tttccatgta aaactaatgt
    10201 gaagactaat gtatttttta tattgcagtg taaaagctaa acttgttttt gatgttatca
    10261 agataaaatt tattaaacct tgaaa
//
