LOCUS       NM_001143978            2940 bp    mRNA    linear   PRI 03-OCT-2024
DEFINITION  Homo sapiens zinc finger CCHC-type containing 18 (ZCCHC18),
            transcript variant 1, mRNA.
ACCESSION   NM_001143978 XR_016527 XR_018173 XR_039901
VERSION     NM_001143978.3
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 2940)
  AUTHORS   Wang,H., Liu,X.L., Shu,S.N., Huang,Y.J. and Fang,F.
  TITLE     Identification of proteins that interact with murine
            cytomegalovirus early protein M112-113 in brain
  JOURNAL   Chin Med J (Engl) 124 (21), 3532-3536 (2011)
   PUBMED   22340173
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC234783.5, DA808943.1, DA790216.1, DA781887.1 and AI656548.1.
            
            On Nov 22, 2018 this sequence version replaced NM_001143978.2.
            
            Transcript Variant: This variant (1) represents the longer
            transcript and encodes the supported protein.
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR1803614.264010.1,
                                           SRR1803612.229377.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA1965299, SAMEA1966682
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000650639.1/ ENSP00000498828.1
            RefSeq Select criteria :: based on expression, longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-3                 AC234783.5         22966-22968         c
            4-183               DA808943.1         4-183
            184-359             DA790216.1         181-356
            360-927             DA781887.1         1-568
            928-2414            AC234783.5         20175-21661         c
            2415-2940           AI656548.1         15-540              c
FEATURES             Location/Qualifiers
     source          1..2940
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="X"
                     /map="Xq22.2"
     gene            1..2940
                     /gene="ZCCHC18"
                     /gene_synonym="PNMA7B; SIZN2"
                     /note="zinc finger CCHC-type containing 18"
                     /db_xref="GeneID:644353"
                     /db_xref="HGNC:HGNC:32459"
                     /db_xref="MIM:301122"
     exon            1..479
                     /gene="ZCCHC18"
                     /gene_synonym="PNMA7B; SIZN2"
                     /inference="alignment:Splign:2.1.0"
     exon            480..531
                     /gene="ZCCHC18"
                     /gene_synonym="PNMA7B; SIZN2"
                     /inference="alignment:Splign:2.1.0"
     exon            532..2940
                     /gene="ZCCHC18"
                     /gene_synonym="PNMA7B; SIZN2"
                     /inference="alignment:Splign:2.1.0"
     CDS             1210..2421
                     /gene="ZCCHC18"
                     /gene_synonym="PNMA7B; SIZN2"
                     /note="putative zinc finger CCHC domain-containing protein
                     18; paraneoplastic Ma antigen family member 7B; zinc
                     finger, CCHC domain containing 12 pseudogene 1"
                     /codon_start=1
                     /product="zinc finger CCHC domain-containing protein 18"
                     /protein_id="NP_001137450.1"
                     /db_xref="CCDS:CCDS65304.1"
                     /db_xref="GeneID:644353"
                     /db_xref="HGNC:HGNC:32459"
                     /db_xref="MIM:301122"
                     /translation="MASITACVGNSRQQNAPLPPWAHSMLRSLGRSLCPLVVKMAERN
                     MKLFSGRVVPAQGKETFENWLIQVNEVLPDWSMSEEEKLKRLMKTLRGPAREVMRLLQ
                     AANPNLSVADFLRAMKLVFGESESSVTAHGKFFNTLQAQGEKASLYVIRLEVQLQNAI
                     QAGILAEKDANQTRLQQLLLGAELNRDLRFRLKHLLRMYANKQERLPNFLELIKMIRE
                     EEDWDDAFIKRKRPKRSEPIMERAASPVAFQGAQPIAISSADCNCNVIEIDDTLDDSD
                     EDVILVVSLYPSLTPTGAPPFRGRARPLDQVLVIDSPNNSGAQSLSTSGGSGYKNDGP
                     GNIRRARKRKYTTRCSYCGEEGHSKETCDNESNKAQVFENLIITLQELTHTEERSKEV
                     PGEHSDASEPQ"
     regulatory      2922..2927
                     /regulatory_class="polyA_signal_sequence"
                     /gene="ZCCHC18"
                     /gene_synonym="PNMA7B; SIZN2"
                     /note="hexamer: AATATA"
     polyA_site      2940
                     /gene="ZCCHC18"
                     /gene_synonym="PNMA7B; SIZN2"
                     /note="major polyA site"
ORIGIN      
        1 gctcttttgt ctcagtcgcc agagactgaa agcaaccgcg gctgcccgga gggccgaact
       61 ggagggtggg cgcagccttg gctgccttgg gaaccgtgct gcctcgactc ggctacccct
      121 cgctgggcgg tcgtgcgcac tcgctaggtc gggcagcccc gggtcgctta gcggccgagg
      181 aggcggcaga gatcccgttc ccctgcagag ctacggggac cggaaggcga aacagagctg
      241 tggacgcggg agcacatgct gcccaccagt ggagcacaag taaagaaaga acgcgcgatt
      301 gcccggcgcg gagaggggtg ggggaagccc cgccaggact gggcggcgcc cggcttggag
      361 aatcagtaac tgcgaggcag gggatggagc actcccttgg cctggttgcg ctgaggaagg
      421 agttgtggtt catctggatg ctgccgactg gataggattt aggatttgcc tggattaagg
      481 tcatcaaagc cgaatccgaa cttgaattct gtgcggcgga ttgcagagct gtcttgaggc
      541 cctgaggact gggatctgcg acacccagtg gacaaaagtc ggccgtaccc cagaggctaa
      601 ttttctcacg gcaggcacct gttgcagagg ctgcacgtaa aataaaggcg aacgctagtt
      661 tccgagctca tgtaagaatc tgagaaataa cgggggaaac gttgacaagg gggtgtgatt
      721 gagacctgag gccatgaggt taatggtttc ttattatcat aaatctgtga cacacaacca
      781 ttgagttccg ttttgagggc ccagtatcag ctcccaacac tatgtcatct agaattagaa
      841 gcaacagttg tcgcccctcc tggagtacag gcaggagggg atggatgtgg ctctgaaaaa
      901 ctacctacta gcccagggac acctgctagc tctggaatgt tgtaattgcc agtctcctgc
      961 agggtattgt taaggcactg ggcagatata aaatgcactg caaggctatt caggaagata
     1021 gagaatgcta ctgcagactg cttccccaca gcccactatc ttattaacct tttttacttt
     1081 ccttagaatc cctactgaaa tataaggcag gcacagccca ggaacgttgc tttggagaat
     1141 cctgcagata aggcttttcc aaaaagcgcg agcatcttgt tgtattcaga taccctatcg
     1201 tcgtcagtca tggctagcat cactgcgtgt gtgggtaaca gcaggcagca gaatgcacct
     1261 ttgccgcctt gggcccattc catgttgagg tctctgggga ggagtctctg tcctttagtg
     1321 gtcaaaatgg cagagagaaa catgaagttg ttctcaggaa gagtggtgcc agcccagggg
     1381 aaagaaacct ttgaaaactg gctgatccaa gtcaatgagg tcctgccaga ttggagtatg
     1441 tctgaggagg aaaaactcaa gcgcttgatg aaaacactta ggggccctgc ccgggaggtc
     1501 atgcgtttgc ttcaggcggc caaccccaac ctaagtgtag cagatttctt gcgggcaatg
     1561 aaattggtgt ttggggagtc tgaaagcagt gtgactgccc atggtaaatt ttttaacacc
     1621 ctgcaggcac aaggggagaa agcctccctt tatgtgatcc gtttagaggt gcagctccag
     1681 aatgctattc aggcaggcat cctagctgag aaagatgcaa accagactcg cttgcaacag
     1741 cttcttttag gcgctgagct gaatagggac ctgcgcttca ggcttaagca tcttctcagg
     1801 atgtatgcaa ataagcagga gcggcttccc aatttcctgg agttaatcaa gatgataagg
     1861 gaggaagagg attgggatga tgcttttatt aaacggaagc ggccgaaaag gtctgagcca
     1921 ataatggaga gggcagccag ccctgtggca tttcagggcg cccagccaat agcaatcagc
     1981 agtgctgact gtaactgcaa cgtgatagaa atagatgata cccttgatga ctctgatgag
     2041 gatgtgatcc tggtggtgtc tctgtaccct tcactgacac ctacaggtgc ccctcccttc
     2101 agaggaagag ccagacctct ggatcaagtg ctggttattg attcccccaa caattctggg
     2161 gctcagtctc tttctaccag tggtggttct gggtataaga atgatggtcc tgggaatatt
     2221 cgtagagcca ggaagcgaaa atacacaacc cgctgctcat attgtgggga ggagggccac
     2281 tcaaaagaaa cctgtgacaa tgagagcaac aaggcccagg tttttgagaa tctgatcatc
     2341 accctgcagg agctgacaca tacagaggag aggtcaaaag aggtccctgg agaacacagt
     2401 gatgcttctg agccacagta aggatctagt ccagccctaa atgagtcctt gactgtattc
     2461 agagtctggt aatgggaata acaggagagg ggggtgggtt tctaactgca tgaattaatc
     2521 cacaaagcag ttttcctttg ggaaggagaa gaggtcttgc ataccagcac agtggatggg
     2581 gaatggtgtg acctctgtcc ctgctctctt ctctgctggc ttaagggtct attctccatg
     2641 tgtctatttc tttgatgact ttatactttt tatgaaagga gcatcttttc attaaacctt
     2701 caaaaataaa ggaagataca aaaactaaag tacaaattac ctgaaactca gcaccctttt
     2761 gtaaccattg tcagcccttt ggtgaatgtc cttccagata tctccctgta cctgtgtacc
     2821 cagatagata tatgtataga taagagtgac caaatataag tgctgttcta tactgtgtat
     2881 ttttcaccaa ataatgtatc tcgtggactt ctatgtcgat gaatatatat aaatatctaa
//
