LOCUS       NM_203303                855 bp    mRNA    linear   PRI 06-SEP-2024
DEFINITION  Homo sapiens zinc finger CCHC-type containing 13 (ZCCHC13), mRNA.
ACCESSION   NM_203303
VERSION     NM_203303.3
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 855)
  AUTHORS   Luck,K., Kim,D.K., Lambourne,L., Spirohn,K., Begg,B.E., Bian,W.,
            Brignall,R., Cafarelli,T., Campos-Laborie,F.J., Charloteaux,B.,
            Choi,D., Cote,A.G., Daley,M., Deimling,S., Desbuleux,A., Dricot,A.,
            Gebbia,M., Hardy,M.F., Kishore,N., Knapp,J.J., Kovacs,I.A.,
            Lemmens,I., Mee,M.W., Mellor,J.C., Pollis,C., Pons,C.,
            Richardson,A.D., Schlabach,S., Teeking,B., Yadav,A., Babor,M.,
            Balcha,D., Basha,O., Bowman-Colin,C., Chin,S.F., Choi,S.G.,
            Colabella,C., Coppin,G., D'Amata,C., De Ridder,D., De Rouck,S.,
            Duran-Frigola,M., Ennajdaoui,H., Goebels,F., Goehring,L., Gopal,A.,
            Haddad,G., Hatchi,E., Helmy,M., Jacob,Y., Kassa,Y., Landini,S.,
            Li,R., van Lieshout,N., MacWilliams,A., Markey,D., Paulson,J.N.,
            Rangarajan,S., Rasla,J., Rayhan,A., Rolland,T., San-Miguel,A.,
            Shen,Y., Sheykhkarimli,D., Sheynkman,G.M., Simonovsky,E., Tasan,M.,
            Tejeda,A., Tropepe,V., Twizere,J.C., Wang,Y., Weatheritt,R.J.,
            Weile,J., Xia,Y., Yang,X., Yeger-Lotem,E., Zhong,Q., Aloy,P.,
            Bader,G.D., De Las Rivas,J., Gaudet,S., Hao,T., Rak,J.,
            Tavernier,J., Hill,D.E., Vidal,M., Roth,F.P. and Calderwood,M.A.
  TITLE     A reference map of the human binary protein interactome
  JOURNAL   Nature 580 (7803), 402-408 (2020)
   PUBMED   32296183
REFERENCE   2  (bases 1 to 855)
  AUTHORS   Li,Z., Li,Z., Wang,L., Long,C., Zheng,Z. and Zhuang,X.
  TITLE     ZCCHC13-mediated induction of human liver cancer is associated with
            the modulation of DNA methylation and the AKT/ERK signaling pathway
  JOURNAL   J Transl Med 17 (1), 108 (2019)
   PUBMED   30940166
  REMARK    GeneRIF: ZCCHC13 functions an oncogene for hepatocellular
            carcinoma, and DNA hypomethylation is a driving factor in
            carcinogenesis.
            Publication Status: Online-Only
REFERENCE   3  (bases 1 to 855)
  AUTHORS   Titulaer,M.K., Mustafa,D.A., Siccama,I., Konijnenburg,M.,
            Burgers,P.C., Andeweg,A.C., Smitt,P.A., Kros,J.M. and Luider,T.M.
  TITLE     A software application for comparing large numbers of high
            resolution MALDI-FTICR MS spectra demonstrated by searching
            candidate biomarkers for glioma blood vessel formation
  JOURNAL   BMC Bioinformatics 9, 133 (2008)
   PUBMED   18312684
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 855)
  AUTHORS   Hahn,Y. and Lee,B.
  TITLE     Identification of nine human-specific frameshift mutations by
            comparative analysis of the human and the chimpanzee genome
            sequences
  JOURNAL   Bioinformatics 21 Suppl 1, i186-i194 (2005)
   PUBMED   15961456
REFERENCE   5  (bases 1 to 855)
  AUTHORS   Chureau,C., Prissette,M., Bourdet,A., Barbe,V., Cattolico,L.,
            Jones,L., Eggen,A., Avner,P. and Duret,L.
  TITLE     Comparative sequence analysis of the X-inactivation center region
            in mouse, human, and bovine
  JOURNAL   Genome Res 12 (6), 894-908 (2002)
   PUBMED   12045143
COMMENT     REVIEWED REFSEQ: This record has been curated by NCBI staff. The
            reference sequence was derived from AC004386.1, BC021176.2 and
            BX109166.1.
            This sequence is a reference standard in the RefSeqGene project.
            
            On May 17, 2019 this sequence version replaced NM_203303.2.
            
            Summary: This gene appears to represent an intronless retrocopy of
            a related multi-exon gene located on chromosome 3. However, the CDS
            of this intronless gene remains relatively intact, it is conserved
            in other mammalian species, it is known to be transcribed, and it
            is therefore thought to encode a functional protein. The encoded
            protein contains six CCHC-type zinc fingers, and is thus thought to
            function as a transcription factor. [provided by RefSeq, May 2010].
            
            ##Evidence-Data-START##
            Transcript is intronless :: BC021176.2, SRR5189667.93693.1
                                        [ECO:0000345]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000339534.4/ ENSP00000345633.2
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-10                AC004386.1         90780-90789
            11-14               BC021176.2         1-4
            15-15               AC004386.1         90794-90794
            16-767              BC021176.2         6-757
            768-855             BX109166.1         438-525
FEATURES             Location/Qualifiers
     source          1..855
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="X"
                     /map="Xq13.2"
     gene            1..855
                     /gene="ZCCHC13"
                     /gene_synonym="CNBP2; ZNF9L"
                     /note="zinc finger CCHC-type containing 13"
                     /db_xref="GeneID:389874"
                     /db_xref="HGNC:HGNC:31749"
                     /db_xref="MIM:301125"
     exon            1..855
                     /gene="ZCCHC13"
                     /gene_synonym="CNBP2; ZNF9L"
                     /inference="alignment:Splign:2.1.0"
     CDS             88..588
                     /gene="ZCCHC13"
                     /gene_synonym="CNBP2; ZNF9L"
                     /note="zinc finger, CCHC domain containing 13"
                     /codon_start=1
                     /product="zinc finger CCHC domain-containing protein 13"
                     /protein_id="NP_976048.1"
                     /db_xref="CCDS:CCDS14425.1"
                     /db_xref="GeneID:389874"
                     /db_xref="HGNC:HGNC:31749"
                     /db_xref="MIM:301125"
                     /translation="MSSKDFFACGHSGHWARGCPRGGAGGRRGGGHGRGSQCGSTTLS
                     YTCYCCGESGRNAKNCVLLGNICYNCGRSGHIAKDCKDPKRERRQHCYTCGRLGHLAR
                     DCDRQKEQKCYSCGKLGHIQKDCAQVKCYRCGEIGHVAINCSKARPGQLLPLRQIPTS
                     SQGMSQ"
     regulatory      828..833
                     /regulatory_class="polyA_signal_sequence"
                     /gene="ZCCHC13"
                     /gene_synonym="CNBP2; ZNF9L"
                     /note="hexamer: ATTAAA"
     polyA_site      855
                     /gene="ZCCHC13"
                     /gene_synonym="CNBP2; ZNF9L"
                     /note="major polyA site"
ORIGIN      
        1 aattctttct aagccgccca aagcggggtt gcgccggggc ctccggggcc gaggtgggcc
       61 tgctcattgg aagatcgcat cgcagccatg agcagtaagg atttcttcgc gtgtggacac
      121 tctggccatt gggctcgggg atgccctaga ggaggagctg gagggcgaag aggtggaggc
      181 catggcagag gttctcaatg tggttccacc accctatctt acacctgtta ctgctgtggt
      241 gagtccggtc gtaatgctaa gaactgtgtc cttctcggaa acatctgcta caactgtggg
      301 agaagcggcc acatcgccaa agactgtaag gatcctaaac gagagagacg ccaacactgt
      361 tatacctgcg gcagactagg acatctggct cgtgactgtg atcgtcagaa agagcagaaa
      421 tgctactctt gcggcaaact tgggcacatt cagaaagact gcgcccaggt caagtgttac
      481 cgatgcggcg agattggcca cgtggccatc aattgcagca aggcgaggcc aggtcaactg
      541 ctaccgctgc ggcaaatccc gacatctagc caaggaatgt cccagtgagg ttaccactta
      601 aatcttcccc cccacccccc acccttttgc tgattgataa ttgtattatt ttctccgaaa
      661 acttcactca ccgaaaggtc gatagattga ggctactctc aggcaagtga gctttaatta
      721 ccatgttaaa ggaggaaaga gctagaaaaa aaaacctcaa aaaagttaat cattggtaga
      781 tgccccacaa ttaacgtgtt gcttctgccc cacgggcaaa tctagttatt aaatagtcat
      841 tctgagcacc aatca
//
