LOCUS       NM_024824              18153 bp    mRNA    linear   PRI 20-FEB-2025
DEFINITION  Homo sapiens zinc finger CCCH-type containing 14 (ZC3H14),
            transcript variant 1, mRNA.
ACCESSION   NM_024824
VERSION     NM_024824.5
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 18153)
  AUTHORS   Li,Q., Yang,G., Ren,B., Liu,X., Tang,L.Q., Shi,Q., Shan,G. and
            Wang,X.
  TITLE     ZC3H14 facilitates backsplicing by binding to exon-intron boundary
            and 3' UTR
  JOURNAL   Mol Cell 84 (22), 4314-4333 (2024)
   PUBMED   39461343
REFERENCE   2  (bases 1 to 18153)
  AUTHORS   Baker,J.D., Uhrich,R.L., Strovas,T.J., Saxton,A.D. and Kraemer,B.C.
  TITLE     AlphaScreen Identifies MSUT2 Inhibitors for Tauopathy-Targeting
            Therapeutic Discovery
  JOURNAL   SLAS Discov 26 (3), 400-409 (2021)
   PUBMED   32981422
  REMARK    GeneRIF: AlphaScreen Identifies MSUT2 Inhibitors for
            Tauopathy-Targeting Therapeutic Discovery.
REFERENCE   3  (bases 1 to 18153)
  AUTHORS   Luck,K., Kim,D.K., Lambourne,L., Spirohn,K., Begg,B.E., Bian,W.,
            Brignall,R., Cafarelli,T., Campos-Laborie,F.J., Charloteaux,B.,
            Choi,D., Cote,A.G., Daley,M., Deimling,S., Desbuleux,A., Dricot,A.,
            Gebbia,M., Hardy,M.F., Kishore,N., Knapp,J.J., Kovacs,I.A.,
            Lemmens,I., Mee,M.W., Mellor,J.C., Pollis,C., Pons,C.,
            Richardson,A.D., Schlabach,S., Teeking,B., Yadav,A., Babor,M.,
            Balcha,D., Basha,O., Bowman-Colin,C., Chin,S.F., Choi,S.G.,
            Colabella,C., Coppin,G., D'Amata,C., De Ridder,D., De Rouck,S.,
            Duran-Frigola,M., Ennajdaoui,H., Goebels,F., Goehring,L., Gopal,A.,
            Haddad,G., Hatchi,E., Helmy,M., Jacob,Y., Kassa,Y., Landini,S.,
            Li,R., van Lieshout,N., MacWilliams,A., Markey,D., Paulson,J.N.,
            Rangarajan,S., Rasla,J., Rayhan,A., Rolland,T., San-Miguel,A.,
            Shen,Y., Sheykhkarimli,D., Sheynkman,G.M., Simonovsky,E., Tasan,M.,
            Tejeda,A., Tropepe,V., Twizere,J.C., Wang,Y., Weatheritt,R.J.,
            Weile,J., Xia,Y., Yang,X., Yeger-Lotem,E., Zhong,Q., Aloy,P.,
            Bader,G.D., De Las Rivas,J., Gaudet,S., Hao,T., Rak,J.,
            Tavernier,J., Hill,D.E., Vidal,M., Roth,F.P. and Calderwood,M.A.
  TITLE     A reference map of the human binary protein interactome
  JOURNAL   Nature 580 (7803), 402-408 (2020)
   PUBMED   32296183
REFERENCE   4  (bases 1 to 18153)
  AUTHORS   Zhang,C., Cao,P., Yang,A., Xia,X., Li,Y., Shi,M., Yang,Y., Wei,X.,
            Yang,C. and Zhou,G.
  TITLE     Downregulation of ZC3H14 driven by chromosome 14q31 deletion
            promotes hepatocellular carcinoma progression by activating
            integrin signaling
  JOURNAL   Carcinogenesis 40 (3), 474-486 (2019)
   PUBMED   30371740
  REMARK    GeneRIF: study suggests that ZC3H14 functions as a novel tumor
            suppressor and is a candidate prognostic biomarker for
            hepatocellular carcinoma patients
REFERENCE   5  (bases 1 to 18153)
  AUTHORS   Bienkowski,R.S., Banerjee,A., Rounds,J.C., Rha,J., Omotade,O.F.,
            Gross,C., Morris,K.J., Leung,S.W., Pak,C., Jones,S.K.,
            Santoro,M.R., Warren,S.T., Zheng,J.Q., Bassell,G.J., Corbett,A.H.
            and Moberg,K.H.
  TITLE     The Conserved, Disease-Associated RNA Binding Protein dNab2
            Interacts with the Fragile X Protein Ortholog in Drosophila Neurons
  JOURNAL   Cell Rep 20 (6), 1372-1384 (2017)
   PUBMED   28793261
REFERENCE   6  (bases 1 to 18153)
  AUTHORS   Wheeler,J.M., Guthrie,C.R. and Kraemer,B.C.
  TITLE     The role of MSUT-2 in tau neurotoxicity: a target for
            neuroprotection in tauopathy?
  JOURNAL   Biochem Soc Trans 38 (4), 973-976 (2010)
   PUBMED   20658987
  REMARK    GeneRIF: New neuroprotective strategies targeting MSUT-2 that may
            be effective in modulating tau neurotoxicity in human tauopathy
            disorders.
            Review article
REFERENCE   7  (bases 1 to 18153)
  AUTHORS   Leung,S.W., Apponi,L.H., Cornejo,O.E., Kitchen,C.M.,
            Valentini,S.R., Pavlath,G.K., Dunham,C.M. and Corbett,A.H.
  TITLE     Splice variants of the human ZC3H14 gene generate multiple isoforms
            of a zinc finger polyadenosine RNA binding protein
  JOURNAL   Gene 439 (1-2), 71-78 (2009)
   PUBMED   19303045
  REMARK    GeneRIF: multiple transcripts encoding several ZC3H14 isoforms
            exist in vivo
REFERENCE   8  (bases 1 to 18153)
  AUTHORS   Guthrie,C.R., Schellenberg,G.D. and Kraemer,B.C.
  TITLE     SUT-2 potentiates tau-induced neurotoxicity in Caenorhabditis
            elegans
  JOURNAL   Hum Mol Genet 18 (10), 1825-1838 (2009)
   PUBMED   19273536
REFERENCE   9  (bases 1 to 18153)
  AUTHORS   Kelly,S.M., Pabit,S.A., Kitchen,C.M., Guo,P., Marfatia,K.A.,
            Murphy,T.J., Corbett,A.H. and Berland,K.M.
  TITLE     Recognition of polyadenosine RNA by zinc finger proteins
  JOURNAL   Proc Natl Acad Sci U S A 104 (30), 12306-12311 (2007)
   PUBMED   17630287
  REMARK    GeneRIF: these proteins are members of an evolutionarily conserved
            family of poly(A) RNA binding proteins
REFERENCE   10 (bases 1 to 18153)
  AUTHORS   Scanlan,M.J., Gordan,J.D., Williamson,B., Stockert,E., Bander,N.H.,
            Jongeneel,V., Gure,A.O., Jager,D., Jager,E., Knuth,A., Chen,Y.T.
            and Old,L.J.
  TITLE     Antigens recognized by autologous antibody in patients with
            renal-cell carcinoma
  JOURNAL   Int J Cancer 83 (4), 456-464 (1999)
   PUBMED   10508479
COMMENT     REVIEWED REFSEQ: This record has been curated by NCBI staff. The
            reference sequence was derived from DB452844.1, BC011793.1,
            BX248769.1, AL359625.1, BC034274.1 and AL162171.4.
            This sequence is a reference standard in the RefSeqGene project.
            
            On Nov 23, 2018 this sequence version replaced NM_024824.4.
            
            Summary: The protein encoded by this gene is a poly(A)-binding
            protein that can affect gene expression and poly(A) tail length.
            The encoded protein may influence mRNA stability, nuclear export,
            and translation. [provided by RefSeq, May 2016].
            
            Transcript Variant: This variant (1) represents the longest
            transcript and encodes the longest isoform (1).
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR1803614.186153.1,
                                           SRR1803613.139502.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA1965299, SAMEA1966682
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000251038.10/ ENSP00000251038.5
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-15                DB452844.1         129-143
            16-2443             BC011793.1         10-2437
            2444-3487           BX248769.1         462-1505
            3488-3551           AL359625.1         742-805
            3552-4066           BC034274.1         203-717
            4067-18153          AL162171.4         20188-34274         c
FEATURES             Location/Qualifiers
     source          1..18153
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="14"
                     /map="14q31.3"
     gene            1..18153
                     /gene="ZC3H14"
                     /gene_synonym="MRT56; MSUT-2; NY-REN-37; SUT2; UKp68"
                     /note="zinc finger CCCH-type containing 14"
                     /db_xref="GeneID:79882"
                     /db_xref="HGNC:HGNC:20509"
                     /db_xref="MIM:613279"
     exon            1..133
                     /gene="ZC3H14"
                     /gene_synonym="MRT56; MSUT-2; NY-REN-37; SUT2; UKp68"
                     /inference="alignment:Splign:2.1.0"
     CDS             98..2308
                     /gene="ZC3H14"
                     /gene_synonym="MRT56; MSUT-2; NY-REN-37; SUT2; UKp68"
                     /note="isoform 1 is encoded by transcript variant 1; zinc
                     finger CCCH domain-containing protein 14; nuclear protein
                     UKp68; renal carcinoma antigen NY-REN-37; mammalian
                     suppressor of tau pathology-2"
                     /codon_start=1
                     /product="zinc finger CCCH domain-containing protein 14
                     isoform 1"
                     /protein_id="NP_079100.2"
                     /db_xref="CCDS:CCDS32133.1"
                     /db_xref="GeneID:79882"
                     /db_xref="HGNC:HGNC:20509"
                     /db_xref="MIM:613279"
                     /translation="MEIGTEISRKIRSAIKGKLQELGAYVDEELPDYIMVMVANKKSQ
                     DQMTEDLSLFLGNNTIRFTVWLHGVLDKLRSVTTEPSSLKSSDTNIFDSNVPSNKSNF
                     SRGDERRHEAAVPPLAIPSARPEKRDSRVSTSSQESKTTNVRQTYDDGAATRLMSTVK
                     PLREPAPSEDVIDIKPEPDDLIDEDLNFVQENPLSQKKPTVTLTYGSSRPSIEIYRPP
                     ASRNADSGVHLNRLQFQQQQNSIHAAKQLDMQSSWVYETGRLCEPEVLNSLEETYSPF
                     FRNNSEKMSMEDENFRKRKLPVVSSVVKVKKFNHDGEEEEEDDDYGSRTGSISSSVSV
                     PAKPERRPSLPPSKQANKNLILKAISEAQESVTKTTNYSTVPQKQTLPVAPRTRTSQE
                     ELLAEVVQGQSRTPRISPPIKEEETKGDSVEKNQGTQQRQLLSRLQIDPVMAETLQMS
                     QDYYDMESMVHADTRSFILKKPKLSEEVVVAPNQESGMKTADSLRVLSGHLMQTRDLV
                     QPDKPASPKFIVTLDGVPSPPGYMSDQEEDMCFEGMKPVNQTAASNKGLRGLLHPQQL
                     HLLSRQLEDPNGSFSNAEMSELSVAQKPEKLLERCKYWPACKNGDECAYHHPISPCKA
                     FPNCKFAEKCLFVHPNCKYDAKCTKPDCPFTHVSRRIPVLSPKPAVAPPAPPSSSQLC
                     RYFPACKKMECPFYHPKHCRFNTQCTRPDCTFYHPTINVPPRHALKWIRPQTSE"
     exon            134..176
                     /gene="ZC3H14"
                     /gene_synonym="MRT56; MSUT-2; NY-REN-37; SUT2; UKp68"
                     /inference="alignment:Splign:2.1.0"
     exon            177..291
                     /gene="ZC3H14"
                     /gene_synonym="MRT56; MSUT-2; NY-REN-37; SUT2; UKp68"
                     /inference="alignment:Splign:2.1.0"
     exon            292..332
                     /gene="ZC3H14"
                     /gene_synonym="MRT56; MSUT-2; NY-REN-37; SUT2; UKp68"
                     /inference="alignment:Splign:2.1.0"
     exon            333..528
                     /gene="ZC3H14"
                     /gene_synonym="MRT56; MSUT-2; NY-REN-37; SUT2; UKp68"
                     /inference="alignment:Splign:2.1.0"
     exon            529..958
                     /gene="ZC3H14"
                     /gene_synonym="MRT56; MSUT-2; NY-REN-37; SUT2; UKp68"
                     /inference="alignment:Splign:2.1.0"
     exon            959..1119
                     /gene="ZC3H14"
                     /gene_synonym="MRT56; MSUT-2; NY-REN-37; SUT2; UKp68"
                     /inference="alignment:Splign:2.1.0"
     exon            1120..1220
                     /gene="ZC3H14"
                     /gene_synonym="MRT56; MSUT-2; NY-REN-37; SUT2; UKp68"
                     /inference="alignment:Splign:2.1.0"
     exon            1221..1376
                     /gene="ZC3H14"
                     /gene_synonym="MRT56; MSUT-2; NY-REN-37; SUT2; UKp68"
                     /inference="alignment:Splign:2.1.0"
     exon            1377..1451
                     /gene="ZC3H14"
                     /gene_synonym="MRT56; MSUT-2; NY-REN-37; SUT2; UKp68"
                     /inference="alignment:Splign:2.1.0"
     exon            1452..1611
                     /gene="ZC3H14"
                     /gene_synonym="MRT56; MSUT-2; NY-REN-37; SUT2; UKp68"
                     /inference="alignment:Splign:2.1.0"
     exon            1612..1844
                     /gene="ZC3H14"
                     /gene_synonym="MRT56; MSUT-2; NY-REN-37; SUT2; UKp68"
                     /inference="alignment:Splign:2.1.0"
     exon            1845..1965
                     /gene="ZC3H14"
                     /gene_synonym="MRT56; MSUT-2; NY-REN-37; SUT2; UKp68"
                     /inference="alignment:Splign:2.1.0"
     exon            1966..2102
                     /gene="ZC3H14"
                     /gene_synonym="MRT56; MSUT-2; NY-REN-37; SUT2; UKp68"
                     /inference="alignment:Splign:2.1.0"
     exon            2103..2194
                     /gene="ZC3H14"
                     /gene_synonym="MRT56; MSUT-2; NY-REN-37; SUT2; UKp68"
                     /inference="alignment:Splign:2.1.0"
     exon            2195..2301
                     /gene="ZC3H14"
                     /gene_synonym="MRT56; MSUT-2; NY-REN-37; SUT2; UKp68"
                     /inference="alignment:Splign:2.1.0"
     exon            2302..18153
                     /gene="ZC3H14"
                     /gene_synonym="MRT56; MSUT-2; NY-REN-37; SUT2; UKp68"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2405..2410
                     /regulatory_class="polyA_signal_sequence"
                     /gene="ZC3H14"
                     /gene_synonym="MRT56; MSUT-2; NY-REN-37; SUT2; UKp68"
                     /note="hexamer: AATATA"
     polyA_site      2445
                     /gene="ZC3H14"
                     /gene_synonym="MRT56; MSUT-2; NY-REN-37; SUT2; UKp68"
                     /note="major polyA site"
     regulatory      4047..4052
                     /regulatory_class="polyA_signal_sequence"
                     /gene="ZC3H14"
                     /gene_synonym="MRT56; MSUT-2; NY-REN-37; SUT2; UKp68"
                     /note="hexamer: AATAAA"
     polyA_site      4066
                     /gene="ZC3H14"
                     /gene_synonym="MRT56; MSUT-2; NY-REN-37; SUT2; UKp68"
                     /note="major polyA site"
     regulatory      5537..5542
                     /regulatory_class="polyA_signal_sequence"
                     /gene="ZC3H14"
                     /gene_synonym="MRT56; MSUT-2; NY-REN-37; SUT2; UKp68"
                     /note="hexamer: ATTAAA"
     polyA_site      5567
                     /gene="ZC3H14"
                     /gene_synonym="MRT56; MSUT-2; NY-REN-37; SUT2; UKp68"
     regulatory      5940..5945
                     /regulatory_class="polyA_signal_sequence"
                     /gene="ZC3H14"
                     /gene_synonym="MRT56; MSUT-2; NY-REN-37; SUT2; UKp68"
                     /note="hexamer: AATAAA"
     polyA_site      5965
                     /gene="ZC3H14"
                     /gene_synonym="MRT56; MSUT-2; NY-REN-37; SUT2; UKp68"
     regulatory      5980..5985
                     /regulatory_class="polyA_signal_sequence"
                     /gene="ZC3H14"
                     /gene_synonym="MRT56; MSUT-2; NY-REN-37; SUT2; UKp68"
                     /note="hexamer: TATAAA"
     polyA_site      5998
                     /gene="ZC3H14"
                     /gene_synonym="MRT56; MSUT-2; NY-REN-37; SUT2; UKp68"
     regulatory      13458..13463
                     /regulatory_class="polyA_signal_sequence"
                     /gene="ZC3H14"
                     /gene_synonym="MRT56; MSUT-2; NY-REN-37; SUT2; UKp68"
                     /note="hexamer: AATAAA"
     polyA_site      13480
                     /gene="ZC3H14"
                     /gene_synonym="MRT56; MSUT-2; NY-REN-37; SUT2; UKp68"
     regulatory      18132..18137
                     /regulatory_class="polyA_signal_sequence"
                     /gene="ZC3H14"
                     /gene_synonym="MRT56; MSUT-2; NY-REN-37; SUT2; UKp68"
                     /note="hexamer: ATTAAA"
     polyA_site      18153
                     /gene="ZC3H14"
                     /gene_synonym="MRT56; MSUT-2; NY-REN-37; SUT2; UKp68"
ORIGIN      
        1 ggaggcggtg gtgtcccggc tgcggggtag gagtccgcgg cagcctccgg gtaagccaag
       61 cgccgcgcag tgctgagttc ccgcacgccg cagagccatg gagatcggca ccgagatcag
      121 ccgcaagatc cggagtgcca ttaaggggaa attacaagaa ttaggagctt atgttgatga
      181 agaacttcct gattacatta tggtgatggt ggccaacaag aaaagtcagg accaaatgac
      241 agaggatctg tccctgtttc tagggaacaa cacaattcga ttcaccgtat ggcttcatgg
      301 tgtattagat aaacttcgct ctgttacaac tgaaccctct agtctgaagt cttctgatac
      361 caacatcttt gatagtaacg tgccttcaaa caagagcaat ttcagtcggg gagatgagag
      421 gaggcatgaa gctgcagtgc caccacttgc cattcctagc gcgagacctg aaaaaagaga
      481 ttccagagtt tctacaagtt cgcaggagtc aaaaaccaca aatgtcagac agacttacga
      541 tgatggagct gcaacccgac taatgtcaac agtgaaacct ttgagggagc cagcaccctc
      601 tgaagatgtg attgatatta agccagaacc agatgatctc attgacgaag acctcaactt
      661 tgtgcaggag aatcccttat ctcagaaaaa acctacagtg acacttacat atggttcttc
      721 tcgcccttct attgaaattt atcgaccacc tgcaagtaga aatgcagata gtggtgttca
      781 tttaaacagg ttgcaatttc aacagcagca gaatagtatt catgctgcca agcagcttga
      841 tatgcagagt agttgggtat atgaaacagg acgtttgtgt gaaccagagg tgcttaacag
      901 cttagaagaa acgtatagtc cgttctttag aaacaactcg gagaaaatga gtatggagga
      961 tgaaaacttt cggaagagaa agttgcctgt ggtaagttca gttgttaaag taaaaaaatt
     1021 caatcatgat ggagaagagg aggaagaaga tgatgattac gggtctcgaa caggaagcat
     1081 ctccagcagt gtgtctgtgc ctgcaaagcc tgaaaggaga ccttctcttc caccttctaa
     1141 acaagctaac aagaatctga ttttgaaggc tatatctgaa gctcaagaat ccgtaacaaa
     1201 aacaactaac tactctacag ttccacagaa acagacactt ccagttgctc ccagaactcg
     1261 aacttctcaa gaagaattgc tagcagaagt ggtccaggga caaagtagga cccccagaat
     1321 aagtcccccc attaaagaag aggaaacaaa aggagattct gtagaaaaaa atcaaggaac
     1381 tcaacagagg caattattat cccgactgca aatcgaccca gtaatggcag aaactctgca
     1441 gatgagtcaa gattactatg acatggaatc catggtccat gcagacacaa gatcatttat
     1501 tctgaagaag ccaaagctgt ctgaggaagt agtagtggca ccaaaccaag agtcggggat
     1561 gaagactgca gattcccttc gggtactttc aggacacctt atgcagacac gagatcttgt
     1621 acaaccagat aaacctgcaa gtcccaagtt tatagtgacg ctggatggtg tccccagccc
     1681 cccaggatac atgtcagatc aagaggagga catgtgcttt gaaggaatga aacccgtaaa
     1741 ccaaactgca gcctcaaaca agggactcag aggtctcctc cacccacagc agttgcactt
     1801 gctgagcagg cagcttgagg acccaaatgg tagcttttct aacgctgaga tgagtgaact
     1861 gagtgtggca cagaaaccag aaaaactttt ggagcgctgc aagtactggc ctgcttgtaa
     1921 aaatggggat gagtgtgcct accatcaccc catctcaccc tgcaaagcct tccccaattg
     1981 taaatttgct gaaaaatgtt tgtttgttca cccaaattgt aaatatgatg caaagtgtac
     2041 taaaccagat tgtcccttca ctcatgtgag tagaagaatt ccagtactgt ctccaaaacc
     2101 agcagttgca ccaccagcac caccttccag tagtcagctc tgccgttact tccctgcttg
     2161 taagaagatg gaatgtccct tctatcatcc aaaacattgt aggtttaaca ctcaatgtac
     2221 aagaccggac tgcacattct accatcccac cattaatgtc ccaccacgac atgccttgaa
     2281 atggattcga cctcaaacca gcgaatagca cccagtcctg cctggcagaa gatcatgcag
     2341 tttggaagtt ttcatgtact gatgaaagat actctacaga acttgtcaaa tctttgaaac
     2401 ttggaatata ttgctttcat aatatgaagt tttattgcct atctatctga agtgtctaat
     2461 ttttcaagtt tgtaagttta ttatgtggtt ttaacattgg gtgtttttgt tttgttttta
     2521 ctatgaaaag acagcttaag gaagagctaa attctgttaa aatatttggg gcatgtttgt
     2581 gcactgctgt tgtgaggatc agcatatgaa attgacatca tggttagtca tggtactgca
     2641 gcttaggggg ctacacggtt gctgtgtgag tggagagatg cagtgaggca gttgtcatta
     2701 ttctaaaaat tgtactactt tcacttttcc caaagattat ataatgttca taatccacca
     2761 tgaaaacagc attggccaaa ggtactgagg ctgcttaaaa tattcaattc tgctttttaa
     2821 tttttaagtg aatttagttt gaaaagcatg attatacagg cctctcaggc tgagtgctac
     2881 tttggtaaag ttcccagttt tcctgccttc tgtgacagga tgaatgaggt gggtatggac
     2941 agtggaggca gctggaatgg caagtgcaga aaataggaac agttctatac agtgctctca
     3001 tttactaata acataatgcc ttctaaataa tttttttggg aaactacatt atcacaaaat
     3061 tatacaaatt tttttacaag tatttacata ctgtatctga aaacagactt taaagtcaca
     3121 agattataaa tgtacatata tattctcaca ttctgaaaaa taacattctc agaatccaca
     3181 gaaaatatac ttagttacta ctgaagataa tttttgaaat gtaaaaatta gatttaaata
     3241 gtatatttta aatgacagaa ctataattac agagatcaga tcagataggt aaactgcaag
     3301 atagatagga tgaaactttt ggcctactgt attacttaca gagttttttt gtgtgtggtt
     3361 tttaaaactg ttaaggcaag aagtgtcaaa tgctttagag ttaaataaca gatcactgat
     3421 ttcaaagact tggtgtatag tgttaaaaat taaagcttaa aaggtggtta gaaaagtgga
     3481 ttaatgcaaa aggggtaata aagactgcaa cattctcagg accaaattaa actgctaaaa
     3541 aaaaaaaaaa agttcattga cttgcttagt cgtatactca aatgatgata aacctacatg
     3601 tgcaaaggct cacgtttaag attgtcaagc cagcagtcta ctgttgtgtt gccattgctt
     3661 ttccattggg agaagaaaga attaaccagt cattaaacca tttggtaagt tgcactttgc
     3721 tgtgctgatc ccacaggaaa ggcttgaaac acgagaagca gcaaagacag agcacacaag
     3781 tgcataaggc tgttgtcttc ggcttgggtg aaatgacagt tcctcttcat tctaaaggtt
     3841 tactccattg aatttaaggc atttgttcat tccagtgttg agatgctttg catctctgca
     3901 gaagaaattt attttaaatt gtttaaatat ctggaaatac ttttagctat catttataaa
     3961 gatagttttg ttctcagttt cactataaat tatagaacaa atgggaaaca agggtttaat
     4021 ttagttcagc cattttacaa ggaaataata aaatactaaa atctgattgt tttttgctat
     4081 ttaatagcca ctgcccagac acatatttaa gagtttaatc tttcagttgc tatggcttat
     4141 gaacaagcta aggttgacca taaaacattt gttggatgac gtggtttaaa atgatcacca
     4201 caaaaaggga ccacaaaaaa aggaaggaaa tgagcatggt tggcgattgg aagcaagggt
     4261 accagagggc acagtgtgct ttggcatgca ttttatacat aaaatgaatg gaacaaaagg
     4321 tgccagaagt cccaggttac acaatcagga gcttagatac tgcacacaaa aataattatc
     4381 tgggttaaaa aagtaaacat agggcagatt ctatatggcc tatcatgttt cttcaccttc
     4441 ccctcgttgc tggctgatac agcgaggtgg tcagctgatg actacttagt caatatgacc
     4501 tttagtcgtg aaactgacag cagcagtgat taaggctgac ttaatcaggt tggccacttt
     4561 gaaggacaga aatgcagtgg aaacagtttt attctatgta gtttacatgc ttaaggttac
     4621 agagtttcta cctgcactgt aatggaaata taatttctct gtagccaaaa gctggcaaac
     4681 ttgacccaga gggaaaattt aaaactgcag caggctcaaa tgtagagtat ttttcttttt
     4741 atgggcaggt tgttcaggga tttttttcct cctttaattt attgactgac tgtaaataca
     4801 tgagtagaaa cttaatagtc atgtatttca aaatttggct taatttagga gaatccactg
     4861 atgaacaagt accaacttac gtttcaagct tcttagcccc ataatcagtc cttcagccac
     4921 agctatttag agctttaaaa ctaccaggtt caatcactgg ttatgctttc tgtgatgtaa
     4981 tttagtcatt tctattttta gtattaacca agtattagac acagaaaata ggtattaaga
     5041 atcttcatat atcctgtcag accaaatggg attccaggaa cctaaagcga tctattatgc
     5101 tataaagata attaacacat taaaaactca tagggtcaat acagcatctt aaacctcaca
     5161 cttagaaaaa tatattttta aatagcagtc tacataattt tcaatcttca ggaaactaca
     5221 gataggctag acagcgaatt cctgaatgat gagtagtgat ctttggcagc atttaaagtg
     5281 aaaagaaata aggatctaag aattcagccc taatccacta aaaaaaggaa ttctaactga
     5341 caagttttta caaatggagt tgggctcatt cattttggaa ataaacctat ggagtggcac
     5401 acatctaaac aaattttccc aatagaaaaa aggctataaa aattttattc caagagtgat
     5461 taaattgtat aatgttgtat atgtgaattt aacacttttg tttacatgtt aaacaaatgt
     5521 gtatatatta gactacatta aatatgcaat tctttcttcc agttaaatac tgttgctccc
     5581 taaaaccctt acattgtaca ccattgggaa tgattgttca tcatactact tttccattag
     5641 tgaggctaca gttatgtttt aaatgtgcga ttacagagat ggcatctgaa cataaactga
     5701 tggctcgaaa atgaaaatgg aaatgtagca gccatatact gctaactttg gatctgttcc
     5761 tgaattcaaa actactagga gaaaagtgtc ctttataaaa aaggacctta ttaatgccta
     5821 aaaaacatca tattctctag gaaagcttgt gtctgtttcc ttagggaaaa tgtttgcctt
     5881 ttaaaaactg tgatccttta ggatgatcat gactttccct ttccttatgg aaatgcaaga
     5941 ataaaatatt tcattaaaca atgaaccttg aaaataaaat ataaacatta agaaaccatt
     6001 ttgctaaaaa gataatgaaa attatccaaa ttgggttttt gagttcttct gtaaagagtg
     6061 ctctacccta aattttccca gcaggtctgc cgaaatcaca cacttcccaa tacaggggga
     6121 cttggccttt accatcaagt attcgatcct tccttgaaat ggcattatct ggcagtgtat
     6181 ggattacgga ttatacccag tgcatatagc aaatattttg aacagatcag tctttcacta
     6241 ttttgatgat tctgggcatt tctccctgtt acagtcttgg gttagcacca cttgaccatg
     6301 cagggttggg ttttggtttt tcttctctgt aattctggtc tcaaagttaa tttctgtagt
     6361 catctcagca tctctcagtg aggtgtatgt acacatttcc agacaaataa gctgcaatca
     6421 gagaagaaaa ttgcagggag ttaattatgt ttttagattt tcataacagt ttaatatttt
     6481 tcagttgtgc tttcaggtta catgtgtaat atttttcctc tttaactcct tttattctgt
     6541 atttgcataa atatgagatt ctgaagagcc atctggttat actaccttct actaatgttg
     6601 actagctgat ttcataaacc aaagctgtag gagttgttgt attaagtctc ttaactagta
     6661 acatagtctg ctcttcatgg gctgagaaag ttactaacct gcagtcatca cctccagcac
     6721 taacaacatg tcgatcacca ctggtaaatc gaatatttgt cacatggggc gaatgaccca
     6781 agaacctttt gtgttttgcc taaaaaacaa tgacagacaa gctcagggca tttggtgcac
     6841 acagaagtca aaggctctta ttaggaacta taatctctat gacaagagct gtggagagag
     6901 tagggagtta gcaccgcagc cagtgattag aatgcttttc agcatgagta gtggatctgc
     6961 aaaaccaggc tgtgtgggca gtcagatgtc tccaggtact ctgaccattt ttctctaagg
     7021 aaaagcattt gaaatttgat aactgattat aggtttggtg aaaagctaat tacagctttt
     7081 gtaggatggt tccaaagatg gtattactcg agggagagga tttgtttcta atagctttta
     7141 tttcaaagta aatagattta gaaagtttgg ggaaaaattt agaaattagg acaaaacatt
     7201 ttaaatatat ggggaaaagt gctgatgata agacatcaaa attaggagta aactgataat
     7261 agtaaacaaa acacaaactt acaaattttt ctggacatgg gaagtcaaat aacttaacca
     7321 tgccaaagtc atctcctgta acaagactga ttcctgaatg agatacacag gcacagttga
     7381 catcagcttt ctcagcatgt ctggaccaga ttcccaaaac ctcatctcct agaatactag
     7441 agggaaggaa caaaagaaaa ctcatcatgg caagtgcggg caggttgact atattcaaaa
     7501 agtttcttgg caattaatct ctaagtaccc tatcatgtta cttaaaatac aggaagtaaa
     7561 ttatggtaag ttgtttggag acctgaattt catcaggata tcaactcctg ccttttaaaa
     7621 atgacatttt ataatttgaa gggtttctag attaatcttt ttaagattaa agtagtactt
     7681 tatgaaaact gatagaacta ttttttcttt tttttttttt gagacggagt tttcgctctt
     7741 gttacccagg ctggagtgca atggcatgat ctcggctcac cgcaacctct gcctcctggg
     7801 ttcaagcaat tctcctgcct cagcctcccg agtagctggg atcacaggca tgcgctaaca
     7861 tgcccggctt attttgtatt tttagtagag acagggtttc tccatgttgg tcaggctagt
     7921 ctcgaactcc cgacctcagg tgatcacccc cgctcggcct cccaaagtgc tgggattaca
     7981 ggctgagcca ccgcgcctga ctgaaaactg atagaactat ttttcaaatt aaaagtgcta
     8041 cttggctggg tccagcagca cataccagta atcccaacat tttgggaggc tgaggcagga
     8101 ggactgcttg aggccaagag tttgagacca gcctgggcaa tattgtgaga tccctatctc
     8161 tacaaaaata aaaatgactt atgacatagg aattaaaaaa atttcagaga tggggtcttg
     8221 ctatgttgcc caggctggta tcaaaacttc taggctcaag tgatcctccc acctcggcct
     8281 gctacatcag agattacagg catgagccac tatatgcctg gctgatacag gaatttgatg
     8341 gcatttttca ttggccaaaa aaatggatag tcatggttac ctgtcataca gccaggaaat
     8401 ttgaacaaat ttggaagctt tgacttctaa tagattcaag atagcattcc tttagataga
     8461 gaattaataa cagttgctta acagcaccca ataccttttt gccagtcatt aaatttagca
     8521 ttaagaaaaa tatcagggta tctttaaagt taaaactttg atttccttaa aaaaaaaact
     8581 tgataaatca tggaaactga taaaacatgg aaatatattc aataaaaagg ggtcccaaca
     8641 tgaacatacc atttcaaaat atggtaacaa aaacttgaaa ctcaattact attccttatt
     8701 ggaatggctc taacagttca gaaataggat tttctaactg gccttcaaag tcagttcttg
     8761 ccttgtgaat atataagtat ttacctagtc catgtagccc aagtaattct gtcaatagcg
     8821 gcatgatcca taagatgttt tcctgaaggc acttcataga catgccgttt atagcagcca
     8881 ctagagacct ttttcatcag attaaaatgg gacaagaatt ccattaggtg agagacaaaa
     8941 tccacagggg gtttacagaa tactagcata ttgctacttg atttacatgt ctaacattat
     9001 taagtatgca aaagatcact acaaaaactt aataggagaa aagctctgat aagtggggga
     9061 ggaaagggga gctgtaggtc agaaggtaca aagggaggag ttgagaagct ggagctctgg
     9121 agctcaggaa ctttaaatgc attcactaac acgaaatgta aaagcagaag aacttgccac
     9181 ctgggtatac agtattggta ctgtacctgg agataactgc tatctgcaga gaagtccatt
     9241 tgaatgacaa agcttggaat gtctttgcag tagctgattc tgttaagagt ggggcccagc
     9301 gttaggtcat aaaaatccac tgagttctca ctagaaccta ctgccagata ccgggaatcc
     9361 ggactaaatc tgaatcaaaa caaaacgtaa aaagtattag accacatgaa gtattataaa
     9421 tacttaagat cagtgacttt tcctttctag ttcttaaaag taacgtgtga taaggcctca
     9481 aatagattta cctgtcagac acaactgatc atgtatactg agattgtctg ggttacatga
     9541 aataaggaag ctttatattt tacttaaatt ttaaatattt ccccaattgt catctcccaa
     9601 ttcctttaaa aacgtctaat ggcttaaaaa aactttctta ggccaggccc agtggctcac
     9661 acctataatc ccagaacttt gggaagcgga ggcgggcaga tcacctgagg tcgagagttt
     9721 gagaccagcc tgaccaacat agagaaaccc tgtctctact aaaaatacaa aattagccag
     9781 gcatggtggt gcacgcctgt aatcccatct actcgggagg ctgaagcagg agaatcgctt
     9841 gaacccagga ggcacaggtt gtggtgagct gagattgcac cattgcactt cagcatgggc
     9901 aacaagagca aaactccaac tcaaaacaaa acaaaacaaa atttaatttt ttaaatagag
     9961 gcggggtctc actatggtcc caaactcctg gcctcaagca atccttcccc cttggcctcc
    10021 caaggtactg ggattacagg tgtgagccac aacacccagt cagaacatct cagcttttaa
    10081 aagccattag cattacataa ttaataagct aacaattcat taagatagtt ttcttccatc
    10141 tggaaaaaac gttgtcttaa tattaagcaa agaacacagc ccagcttaac taacctccag
    10201 ttattaaggt gaaatgacac aacttgaatc ttggaagaag aatttttttt ttttgagacg
    10261 aagtctcgct cttgtctccc aggctggagt gcgatggcgc aacctccgcc tcccgggttc
    10321 aagcgattct cctgtttcag ccccctgagt agctgggatt acaggcgcct gccaccacgc
    10381 ccggctgatt tttgtatttt tagttgagat ggggtttcac tatgttggcc aggctggtcg
    10441 agtactcctg acttcaggtg atctgcctgc ctcggcctcc caaagtgctg ggattacagg
    10501 catgagccac cgcgcccggc ctgaagaact tatttaaaag acaaagtgaa atgctatttg
    10561 cctagcaatc tttggagtca tatgggacaa ttcagtctct tgaaatggcc catgagtctt
    10621 actgaggtac gatagagaca tgtaaaagct aagggaagcc actgttacta ttttatatat
    10681 tgaagttctg aggaaggttt catttgtaaa aggattttac tgatgaaaag tgtacaagct
    10741 tttgacagac ctagattcaa taatcttatc tactgatcac acggaagtac tccgtaaatg
    10801 gtagccactg ttgaaaaatg cttaagcact gaaaaacaaa ggtttaagaa acatttaaat
    10861 taatttggat tctggaacat ttaatcaata ggtattgatt aaattaatga actacatatt
    10921 cccaaactga ggttactaag agaagatatg tttgaaatca caactttagt tttccagggt
    10981 gacaactttt gaagggcaga tagctctctt gtattacagt gggagatacc tcttggtggg
    11041 atgaacttaa tggacatggc taagtgttaa catgaattca tcaaacatta cctactagta
    11101 cttgctatta tagttggtgc ccagtgggtt tataatttag caagaagaat taagtagtat
    11161 acaaacagcc atattttagc atacaattta taatacggga aatgctacag gccctgggga
    11221 cctctttttg aaggcaaggc tatggaaaat tttacaaatg gaagttaaat caagtatata
    11281 ctagaaactc tattccattt gttcactaac ctgatatcat ggattgcaca tctcctgtct
    11341 ctcttctttc cccatatttt tagagaactc actagtaaaa tgataaattc tccatttttc
    11401 attccaatag ccaccatgtc cccttcaggg ctgtaacaca cagtacgagc agcatgtccc
    11461 aaattcactt tgtttaacat cttctgcatt taaaaaaaaa aaaaaaaaga gtcataggaa
    11521 acattaagtg aagtacttct aaattatacc agtttcccct caaaatgctc aacagaattc
    11581 tggcagttct ttaagtacta gcaatttaga acttccaact tttcttttta gaagttgtaa
    11641 cctcttttaa aaaaattatc tgtacttact ttatcagcaa tatcccaaag tctcactgtc
    11701 ccatcttctg cagcagaaag gaaaaaatcc ctggaaggat gtgttgctag tccccagatt
    11761 ggcccatcca catgaccgtt aactaaaata ttacaagctg catttttctc tccaacttcg
    11821 attatttcag cattccttgt cccaacaagg atcttgccct gaaacacaag caggaccaat
    11881 acagtgaatg taatacaaca gctgcttttc ttcttcataa tataaaaatg accctattga
    11941 cctgctttca gagaactttt tgctttgagc taatctagta gcaaggcagt cattagctca
    12001 tgcaaatttt tctatgacta caggcacaca tctatctgta agcacaatgg gctagattac
    12061 atattagagt ccatgctaca gaatagaact tttctgtggc agtacacctg gattcttcaa
    12121 taatcaaagt ttttatttga taatcttagg atttccaaac tggggtcagt gcagtgggat
    12181 ataggaaaaa ataatagaat ttatttttta gttaaaaagt aaaagcttaa ctacaattta
    12241 atatgcaggc tgaagataat atccgtatga tttataaata cacttaataa gtacaaacac
    12301 gctcaaaaat tttcatagga gttgtagttt tgaattttta ttttgaaatt gacacataat
    12361 tatacatatc tatagggcat agggtaatac gcataaccat cacctcagac atttatcatt
    12421 tctttgtgat ggaaactttc aaaatcctct cttgtaaata cctgaaaata cataaatacg
    12481 tgattcttaa ctatagtcat cctacagtac tacagaatac taaaacatac tattcctatc
    12541 tggctgtgta aacttgtatc ctttaaccag tccttcccta tccccctccc cctccccctt
    12601 gtccgcctcc agtaaccact attctactct ccacctctgt gggatcaact tttttagttt
    12661 ctgcacagga gtgagaacat gtatttatct ttctgtgcct ggcttatttc acttcacatc
    12721 atgtcctcca gtctcatcca tgttgccacc aagaatgaca gaatttcatt attttttatg
    12781 gctgagtagt atttcattgt ttgtttactg cacgttttat ctagggaatg tgtgtttttt
    12841 taaaaaatgg agacagctgt cctaatatga gtcaactgcc aagggctttc aattatgtct
    12901 actagagttg ttaaattggc agattctaga aaatattgga ggtttacata cagtatttag
    12961 acagaatagc ttcctagctt atgcaccaca ctggtgctaa ctttggcaaa gaaagcagca
    13021 aagacagagt aatgttggca agcaaatcca tcgttatgca ttattaagta ttgttcatta
    13081 ggctgcaaag ggtgagggaa tcacagtaat aaccactttc tgttttctgc tgcactgtat
    13141 cagctcatgg aacatcttac tttgcctctg cacacagaac gaacacaatc tgtggcttgt
    13201 cctgtctcaa gcctgaaggc acggcaccgc ctcagttcct gatcccacag tttaaccgct
    13261 cctccttctt ttgacctaag taaataacca agccagagta agtgttcatt attggctact
    13321 ataattttta ttataaacaa ataccaagtt ataagcagaa tctttttttt ttaaaaaggc
    13381 cctgatattt ataatttacc tctaatattc ttgtaaactt tctatggcaa tttgaggata
    13441 tactatatct cagtcaaaat aaacatccag tttcagtgaa ttttattttg agaaatactc
    13501 tttttttctg acatgagcat aattttattt agcctctaca atacattaca atacattatc
    13561 ctctctcata atactttttt tttttttttt aagatgtagt ctcgctctgt ctcccaggct
    13621 tgagtgcagt ggcatgatct aggcttattg caacctctgc ctcccaggtt caagcgattc
    13681 tcctacctca gcctcccgag tagctagcat tacaggtgtg caccaccaca cccagctaat
    13741 ttctgtattt ttagtagaga tggggtttca ccatgttggc caggctggtc tcaaatacct
    13801 tgacctcagg tgatctgcct gcctcggcct cccaaagtgc tgggattcca ggtatgagcc
    13861 actgtgcctg gcctcataat acttcttgat taggaagatg taaaaaaaca attttattaa
    13921 aaggataatg gaaatgtaag gcaaaataat agaattacaa atgctatgct acagagttga
    13981 tttatttatt tttttgagac agagtgtcgc tctgtcacct ggcctggagt gcagtggtgt
    14041 gatctcggct cactgcaacc tgtgcctccc aggttcaagc gattcttctc cttcagcctc
    14101 ccaagtagct gggattacag gcaccatgcc tggctaattt ttgtattttt agtagagatg
    14161 gagtttcacc atattggcca ggctgatccc aaactcctga cctcgtgatc cgcccacctc
    14221 ggcctcccaa agtgttggga ttacaggcgt gagccactgc aactggccca gagcttattt
    14281 ttgaaggcca aaacagaagc atatttattc cctatcaggt gttaaaatat ctcactggaa
    14341 cagtttagca ggcttctagt gagtgggggt gtgcaggagt aaatgacgtg ggaaatacaa
    14401 gtgttggagg acgaaataga gcccatttat ggattttatt cctggaaggg ctgaaaaatg
    14461 tattccttcc ttttctgcta gatgaattgc ttgtctgaaa gcatgcctat gtgcattctt
    14521 cctttatgta aaaggcacaa attctgcgct tgtgtttaat taacatatgt gggttctttc
    14581 aatcctgtat tgaaatgtac ttcttagtca actatatgtc acattttttt ttgtttttgt
    14641 ttttgttttt taaatggggt ctcactctgt cacccaggct ggagtgcagt ggcaccatca
    14701 cagctcacta aagccttgac ctccccaggc tcaagtgatc ctcccacctc agcctcctga
    14761 gtagcaggga ctacaggcat gtgccaccac acccggctaa ttgttgtttt ttatagcgat
    14821 ggggtttcac catgttgccc aggctggtct tgaactcctg ggctcaagcg atccacctgc
    14881 ctcagcctcc caaagtgata agattacagg tgtgagccac tgtgcctggc ctacatgtca
    14941 tgtttcaaca tgcatatgac tatgttggtg acaaatcaaa tcataagtat ctggttactg
    15001 ttgggagatt tgaaaatcac tcagaagaga cctcttctca aattttgagg tcttgtataa
    15061 aacagtttaa atttgcctca agcaaaagga aacaaggcag ttctctctag ttccctcatc
    15121 cttttctaaa gcaacaatgt gcattctact ccttagaatc cattctgaac aaaaagagag
    15181 caggcagtca aaatacaacc ctggctccag attcccccat gggcctccta ctcagcaaat
    15241 catacacagg catacagaca ttaagaaaag taactcaact tgtaggacaa ctacctatcc
    15301 acacctcaga aaaagtatca ccccaacatg aaaaaaattg gaagtgaatt aagaccagaa
    15361 atgagaatca aatagaaggc acataaaagg taataaagga gaagcatatg aggaggaagg
    15421 tcggagagga cactctgtgt agcctagaaa caactagaat aattaactgc aaacctcagg
    15481 taggtcacaa atgcataaat attctgtgaa aagaaagagg actcacggcc tttcctttcc
    15541 cccagtcacg ataagtccat ctcgcagggt ggtgtacatg gcaaacacag gcccgttgtg
    15601 agctctcgcc acgattctac acaatatgtg atctttccac acacagacat caccactgat
    15661 ggtacctgta aacgtcaagt tattctgaaa aggagtgggg gagggggaga caaactcatc
    15721 aaaagttcaa atagagttta aatagataat tttctatgta tgtgtaatgc tgtctcaccc
    15781 ttgatacaaa gagcatgcat cgtgtagtgg cagcagcact gaattcacga gtcaggaaac
    15841 ctgaacggga ggcttagctt tgtcaggacc ttttcctttc caagtctgtt gcttattagc
    15901 tagaataacc ttagacaatt cttcccttcc aattctaaca tactataatt ctagggttta
    15961 ttttttattt ttttgagacg gagtttcgct ctttgttgcc caggctggag tgcaatggtg
    16021 cgatctcagc tcaccacaac ctctgcttcc caggttcaag tgattctcct gtctcagcct
    16081 cccaagtagc tgggattaca agcgccagcc accacgcccg gctaattttt gtatttttag
    16141 tagagacaga gtttcacctt gttagccagg ctggtcttga actcctgact tcaggtgatc
    16201 ttcccgcctt ggcctcccta agtgctggga ttataggtgt gagccactgt gcccggcctg
    16261 agccacggtg cctggcctgg tcttatatta agaataccca aaatgttcaa ctgaaatttg
    16321 acatggcaca aacatttcaa tagtcttttt ctcaaaaatg taagtgtact taaatattct
    16381 aaaattataa cttttcctat aagtattgca taatcacaaa aacaaaaaat gcacttagtt
    16441 tttcgatgca ccaaaggatt tatacagcct agccaatgca ggatattaaa ggaaagagat
    16501 gtggattgga agccacaggt ccagatgaga tggaataaag tgagaggaga gcaggtctcc
    16561 tgaacaccct tctgtcaggg ccaggaattg tgctatttcc ttctgtctca ctacctcctt
    16621 cttccctcga agtagagaca ctggcccaga gcacttccag ctgtatgata agcagtgtgt
    16681 taaatgataa aaagcaaagg aaatcctaaa ccctagtacc accttaaatc atttgaaaat
    16741 catgtttctt gatttacctt tctctctgac aaatttttag gactatgaag aactactagg
    16801 aagacagaaa ttttaggata tttagggtga caattagaag attaaggaag gcttttgagt
    16861 ataacagtag tccaaggaat caaatgttca tcagaatcct tattatggtg gctcatgcct
    16921 gtaaacccag cactttggga ggtcaagatg ggaggatcac atagcttagg agcttgagac
    16981 cacctaggca acatagcgaa accctgtctc tactaaaaat gaaagaaaaa ttagcctagc
    17041 atggtggttc ctgccctgta gtcccagcta ctaaggaggc tgaggatcac ttgaacctgg
    17101 gagatggagg ctacagtgag ctataatcgc accattgcac cccagcccag gcgacagagt
    17161 gagatactgt gtcaaaaaaa aaaaaaaatc cttttccccc tctcattaac attcttttca
    17221 ctccctaatt tctgaaagaa ctagattttt gaaagatgaa atatatgctt gaccagggca
    17281 tgtaatgatt agcagatcac agtatcatct caacaacatt catgtggctg atgatctaag
    17341 gcaagagaat gtaaagtagt caaagtcaca ctatgtgcat tttaagagac atactgcacc
    17401 aaatgcaata gcgagcatgg tctgcatccg ggcatcttcc agtgtgctca gtagcccttt
    17461 tttgctaaga agagctcttc ctgccagggt ccagaacttc acatgtttta ctcccactga
    17521 gacaaactgg gtatctgaat ctggtcggaa ttctgccaca aaaatacgtt gattgtgacc
    17581 agctctgctg gcaattttgg cacctgacaa gatacaacaa aattatctag gttattacaa
    17641 gaaccaagct aatcaacagc atcaaacaaa tatgtaaaat acatagttca aaaaacaaag
    17701 gcttagaaga gaggccaatg gcccctgctc tactacctag caatacatga tttacaatta
    17761 tttgtgtatt gagtcctttt cacttatctt cgctccatta acttttcttt atataacgta
    17821 aatgttttgt ctaaagtgtg gtaggtaata ttatcctgct gatctgccat tatcattaga
    17881 aatatacata attttcataa gaatctccaa aaccaatcaa atcattaata ataaatacat
    17941 agtttcttgc tggaagaaaa tagcagtgaa tcatttataa tgctaataat ggtttcatta
    18001 atttatctgt tttgtgaggt tacagttcca ctgggctttt aaagtgaaat atacctacag
    18061 taccactgtg tacagtatat tgcataggcc tccactgaat gattgtttca accaccaact
    18121 ttaagacaaa tattaaatac agaattccta cta
//
