LOCUS       NM_015898               6437 bp    mRNA    linear   PRI 24-OCT-2024
DEFINITION  Homo sapiens zinc finger and BTB domain containing 7A (ZBTB7A),
            transcript variant 1, mRNA.
ACCESSION   NM_015898
VERSION     NM_015898.4
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 6437)
  AUTHORS   Kambe,G., Kobayashi,M., Ishikita,H., Koyasu,S., Hammond,E.M. and
            Harada,H.
  TITLE     ZBTB7A forms a heterodimer with ZBTB2 and inhibits ZBTB2
            homodimerization required for full activation of HIF-1
  JOURNAL   Biochem Biophys Res Commun 733, 150604 (2024)
   PUBMED   39197198
  REMARK    GeneRIF: ZBTB7A forms a heterodimer with ZBTB2 and inhibits ZBTB2
            homodimerization required for full activation of HIF-1.
REFERENCE   2  (bases 1 to 6437)
  AUTHORS   Wang,Y., Zeng,H., Li,L., Liu,J., Lin,J., Bie,Y., Wang,S., Cheng,X.,
            Nashun,B., Yao,Y., Hu,X. and Zhao,Y.
  TITLE     Pokemon inhibits Bim transcription to promote the proliferation,
            anti-anoikis, invasion, histological grade, and dukes stage of
            colorectal neoplasms
  JOURNAL   J Cancer Res Clin Oncol 150 (8), 380 (2024)
   PUBMED   39095579
  REMARK    GeneRIF: Pokemon inhibits Bim transcription to promote the
            proliferation, anti-anoikis, invasion, histological grade, and
            dukes stage of colorectal neoplasms.
            Publication Status: Online-Only
REFERENCE   3  (bases 1 to 6437)
  AUTHORS   Athanasopoulou,K., Chondrou,V., Xiropotamos,P., Psarias,G.,
            Vasilopoulos,Y., Georgakilas,G.K. and Sgourou,A.
  TITLE     Transcriptional repression of lncRNA and miRNA subsets mediated by
            LRF during erythropoiesis
  JOURNAL   J Mol Med (Berl) 101 (9), 1097-1112 (2023)
   PUBMED   37486375
  REMARK    GeneRIF: Transcriptional repression of lncRNA and miRNA subsets
            mediated by LRF during erythropoiesis.
REFERENCE   4  (bases 1 to 6437)
  AUTHORS   Chang,H., Sun,W., Zhao,Y., Sun,T. and Zhao,Z.
  TITLE     Targeting Pokemon is a novel strategy to suppress cancer
            aggressiveness of non-small cell lung cancer: Identification of
            Pokemon as ideal target for developing anti-NSCLC drugs
  JOURNAL   Arch Biochem Biophys 742, 109637 (2023)
   PUBMED   37182800
  REMARK    GeneRIF: Targeting Pokemon is a novel strategy to suppress cancer
            aggressiveness of non-small cell lung cancer: Identification of
            Pokemon as ideal target for developing anti-NSCLC drugs.
REFERENCE   5  (bases 1 to 6437)
  AUTHORS   Bae,S.Y., Bergom,H.E., Day,A., Greene,J.T., Sychev,Z.E., Larson,G.,
            Corey,E., Plymate,S.R., Freedman,T.S., Hwang,J.H. and Drake,J.M.
  TITLE     ZBTB7A as a novel vulnerability in neuroendocrine prostate cancer
  JOURNAL   Front Endocrinol (Lausanne) 14, 1093332 (2023)
   PUBMED   37065756
  REMARK    GeneRIF: ZBTB7A as a novel vulnerability in neuroendocrine prostate
            cancer.
            Publication Status: Online-Only
REFERENCE   6  (bases 1 to 6437)
  AUTHORS   Pessler,F. and Hernandez,N.
  TITLE     Flexible DNA binding of the BTB/POZ-domain protein FBI-1
  JOURNAL   J Biol Chem 278 (31), 29327-29335 (2003)
   PUBMED   12750370
  REMARK    GeneRIF: found that FBI-1 binds to inverted sequence repeats
            downstream of the HIV-1 transcription start site
REFERENCE   7  (bases 1 to 6437)
  AUTHORS   Lee,D.K., Suh,D., Edenberg,H.J. and Hur,M.W.
  TITLE     POZ domain transcription factor, FBI-1, represses transcription of
            ADH5/FDH by interacting with the zinc finger and interfering with
            DNA binding activity of Sp1
  JOURNAL   J Biol Chem 277 (30), 26761-26768 (2002)
   PUBMED   12004059
  REMARK    GeneRIF: POZ domain of FBI1 represses transcription of ADH5.
REFERENCE   8  (bases 1 to 6437)
  AUTHORS   Pendergrast,P.S., Wang,C., Hernandez,N. and Huang,S.
  TITLE     FBI-1 can stimulate HIV-1 Tat activity and is targeted to a novel
            subnuclear domain that includes the Tat-P-TEFb-containing nuclear
            speckles
  JOURNAL   Mol Biol Cell 13 (3), 915-929 (2002)
   PUBMED   11907272
  REMARK    GeneRIF: Results suggest that FBI-1 is a cellular factor that
            preferentially associates with active chromatin and that can
            specifically stimulate Tat-activated HIV-1 transcription.
REFERENCE   9  (bases 1 to 6437)
  AUTHORS   Morrison,D.J., Pendergrast,P.S., Stavropoulos,P., Colmenares,S.U.,
            Kobayashi,R. and Hernandez,N.
  TITLE     FBI-1, a factor that binds to the HIV-1 inducer of short
            transcripts (IST), is a POZ domain protein
  JOURNAL   Nucleic Acids Res 27 (5), 1251-1262 (1999)
   PUBMED   9973611
REFERENCE   10 (bases 1 to 6437)
  AUTHORS   Davies,J.M., Hawe,N., Kabarowski,J., Huang,Q.H., Zhu,J.,
            Brand,N.J., Leprince,D., Dhordain,P., Cook,M., Morriss-Kay,G. and
            Zelent,A.
  TITLE     Novel BTB/POZ domain zinc-finger protein, LRF, is a potential
            target of the LAZ-3/BCL-6 oncogene
  JOURNAL   Oncogene 18 (2), 365-375 (1999)
   PUBMED   9927193
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC016586.9 and BC084568.1.
            
            On Nov 22, 2018 this sequence version replaced NM_015898.3.
            
            Transcript Variant: This variant (1) represents the longer
            transcript. Variants 1 and 2 encode the same protein.
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR1163657.474873.1, AF000561.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA1968540, SAMEA1968968
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000322357.9/ ENSP00000323670.3
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-218               AC016586.9         91719-91936         c
            219-1891            BC084568.1         61-1733
            1892-6437           AC016586.9         68340-72885         c
FEATURES             Location/Qualifiers
     source          1..6437
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="19"
                     /map="19p13.3"
     gene            1..6437
                     /gene="ZBTB7A"
                     /gene_synonym="FBI-1; FBI1; LRF; MNDLFH; pokemon; TIP21;
                     ZBTB7; ZNF857A"
                     /note="zinc finger and BTB domain containing 7A"
                     /db_xref="GeneID:51341"
                     /db_xref="HGNC:HGNC:18078"
                     /db_xref="MIM:605878"
     exon            1..218
                     /gene="ZBTB7A"
                     /gene_synonym="FBI-1; FBI1; LRF; MNDLFH; pokemon; TIP21;
                     ZBTB7; ZNF857A"
                     /inference="alignment:Splign:2.1.0"
     exon            219..1495
                     /gene="ZBTB7A"
                     /gene_synonym="FBI-1; FBI1; LRF; MNDLFH; pokemon; TIP21;
                     ZBTB7; ZNF857A"
                     /inference="alignment:Splign:2.1.0"
     CDS             234..1988
                     /gene="ZBTB7A"
                     /gene_synonym="FBI-1; FBI1; LRF; MNDLFH; pokemon; TIP21;
                     ZBTB7; ZNF857A"
                     /note="zinc finger and BTB domain containing 7A, HIV-1
                     inducer of short transcripts binding protein; lymphoma
                     related factor; HIV-1 1st-binding protein 1;
                     TTF-I-interacting peptide 21; factor binding IST protein
                     1; leukemia/lymphoma-related factor; POK erythroid myeloid
                     ontogenic factor; pokemon 1; POZ and Krueppel erythroid
                     myeloid ontogenic factor; factor that binds to inducer of
                     short transcripts protein 1; zinc finger protein 857A"
                     /codon_start=1
                     /product="zinc finger and BTB domain-containing protein
                     7A"
                     /protein_id="NP_056982.1"
                     /db_xref="CCDS:CCDS12119.1"
                     /db_xref="GeneID:51341"
                     /db_xref="HGNC:HGNC:18078"
                     /db_xref="MIM:605878"
                     /translation="MAGGVDGPIGIPFPDHSSDILSGLNEQRTQGLLCDVVILVEGRE
                     FPTHRSVLAACSQYFKKLFTSGAVVDQQNVYEIDFVSAEALTALMDFAYTATLTVSTA
                     NVGDILSAARLLEIPAVSHVCADLLDRQILAADAGADAGQLDLVDQIDQRNLLRAKEY
                     LEFFQSNPMNSLPPAAAAAAASFPWSAFGASDDDLDATKEAVAAAVAAVAAGDCNGLD
                     FYGPGPPAERPPTGDGDEGDSNPGLWPERDEDAPTGGLFPPPVAPPAATQNGHYGRGG
                     EEEAASLSEAAPEPGDSPGFLSGAAEGEDGDGPDVDGLAASTLLQQMMSSVGRAGAAA
                     GDSDEESRADDKGVMDYYLKYFSGAHDGDVYPAWSQKVEKKIRAKAFQKCPICEKVIQ
                     GAGKLPRHIRTHTGEKPYECNICKVRFTRQDKLKVHMRKHTGEKPYLCQQCGAAFAHN
                     YDLKNHMRVHTGLRPYQCDSCCKTFVRSDHLHRHLKKDGCNGVPSRRGRKPRVRGGAP
                     DPSPGATATPGAPAQPSSPDARRNGQEKHFKDEDEDEDVASPDGLGRLNVAGAGGGGD
                     SGGGPGAATDGNFTAGLA"
     exon            1496..6437
                     /gene="ZBTB7A"
                     /gene_synonym="FBI-1; FBI1; LRF; MNDLFH; pokemon; TIP21;
                     ZBTB7; ZNF857A"
                     /inference="alignment:Splign:2.1.0"
     regulatory      4501..4506
                     /regulatory_class="polyA_signal_sequence"
                     /gene="ZBTB7A"
                     /gene_synonym="FBI-1; FBI1; LRF; MNDLFH; pokemon; TIP21;
                     ZBTB7; ZNF857A"
                     /note="hexamer: AATAAA"
     polyA_site      4522
                     /gene="ZBTB7A"
                     /gene_synonym="FBI-1; FBI1; LRF; MNDLFH; pokemon; TIP21;
                     ZBTB7; ZNF857A"
                     /note="major polyA site"
     regulatory      6415..6420
                     /regulatory_class="polyA_signal_sequence"
                     /gene="ZBTB7A"
                     /gene_synonym="FBI-1; FBI1; LRF; MNDLFH; pokemon; TIP21;
                     ZBTB7; ZNF857A"
                     /note="hexamer: ACTAAA"
     polyA_site      6437
                     /gene="ZBTB7A"
                     /gene_synonym="FBI-1; FBI1; LRF; MNDLFH; pokemon; TIP21;
                     ZBTB7; ZNF857A"
                     /note="major polyA site"
ORIGIN      
        1 ggagaaacca ggaagggagt cgcgagcatc atacggggct ttggctgtac tgtacagtta
       61 ctgtaggggc agtgacgccg ccgccgccgc gcgagggagc gaccagggca gcgcgacgcg
      121 ggcagagcga gcgccgcgga ccccggaggc gagcggccga gggagcccag tcccaacttc
      181 gggccccggc cccgcgcgcc ccggcccggc cccgcgaggt ctcggcgcgg aagatggccg
      241 gcggcgtgga cggccccatc gggatcccgt tccccgacca cagcagcgac atcctgagtg
      301 ggctgaacga gcagcggacg cagggcctgc tgtgcgacgt ggtgatcctg gtggagggcc
      361 gcgagttccc cacgcaccgc tcggtgctgg ccgcctgcag ccagtacttc aagaagctgt
      421 tcacgtcggg cgccgtggtg gaccagcaga acgtgtacga gatcgacttc gtcagcgccg
      481 aggcgctcac cgcgctcatg gacttcgcct acacggccac gctcaccgtc agcacagcca
      541 acgtgggtga catcctcagc gccgcccgcc tgctggagat ccccgccgtg agccacgtgt
      601 gcgccgacct cctggaccgg cagatcctgg cggccgacgc gggcgccgac gccgggcagc
      661 tggaccttgt agatcaaatt gatcagcgca acctcctccg cgccaaggag tacctcgagt
      721 tcttccagag caaccccatg aacagcctgc cccccgcggc cgccgccgcc gctgccagct
      781 tcccgtggtc cgcctttggg gcgtccgatg atgacctgga tgccaccaag gaggccgtgg
      841 ccgccgctgt ggccgccgtg gccgcgggcg actgcaacgg cttagacttc tatgggccgg
      901 gccccccggc cgagcggccc ccgacggggg acggggacga gggcgacagc aacccgggtc
      961 tgtggccaga gcgggatgag gacgccccca ccgggggtct ctttccgccg ccggtggccc
     1021 cgccggccgc cacgcagaac ggccactacg gccgcggcgg agaggaggag gccgcctcgc
     1081 tgtcggaggc ggcccccgag ccgggcgact ctccgggctt cctgtcggga gcggccgagg
     1141 gcgaggacgg ggacgggccc gacgtggacg ggctggcggc cagcacgctg ctgcagcaga
     1201 tgatgtcatc ggtgggccgg gcgggggccg cggcggggga cagcgacgag gagtcgcggg
     1261 ccgacgacaa gggcgtcatg gactactacc tgaagtactt cagcggcgcc cacgacggcg
     1321 acgtctaccc ggcctggtcg cagaaggtgg agaagaagat ccgagccaag gccttccaga
     1381 agtgccccat ctgcgagaag gtcatccagg gcgccggcaa gctgccgcga cacatccgca
     1441 cccacacggg cgagaagccc tacgagtgca acatctgcaa ggtccgcttc accaggcagg
     1501 acaagctgaa ggtgcacatg cggaagcaca cgggcgagaa gccgtacctg tgccagcagt
     1561 gcggcgccgc ctttgcccac aactacgacc tgaagaacca catgcgcgtg cacacgggcc
     1621 tgcgccccta ccagtgcgac agctgctgca agaccttcgt ccgctccgac cacctgcaca
     1681 gacacctcaa gaaagacggc tgcaacggcg tcccctcgcg ccgcggccgc aagccccgcg
     1741 tccggggcgg ggcgcccgac cccagcccgg gggccaccgc gacccccggc gcccccgccc
     1801 agcccagctc ccccgacgcc cggcgcaacg gccaggagaa gcactttaag gacgaggacg
     1861 aggacgagga cgtggccagc cccgacggct tgggccggtt gaatgtagcg ggcgccggtg
     1921 gaggaggtga cagcggaggt ggccccgggg ccgccaccga cggtaacttc acagccggac
     1981 tcgcctaaaa accaaaaaga gaaaacagaa acccgagaaa gagagagaca gagagagaga
     2041 aaaaaaatca cccaccaccc ccccaaaaac acaaaaaaag aaaatctatc tatatacaga
     2101 tatctatatc tatatatata tatacagata tatatatatg acgcgtcaca gaatctaggg
     2161 tagcgctttc tcagatttcc ctcctttctg acgtttttct ccctccgcag gggccccggc
     2221 cctccctggc tccccttccc cccaccaccc catcgctggg tttcggggct tggtttgggg
     2281 ttttttgtag gacacaagga atccgagacc ccgcacagcc ccctgggcac ccggcatggg
     2341 gcctggggcc cgatccgagg ccctgggctg gggggagggt agacgtgggg gcgctggggg
     2401 gggactgggg tgggctttta atttcctccc ctcgctggtt tctatgagtc tttcagacaa
     2461 gaccttaaat gatttctgtc tgctctgagc ggacgttaaa atgggccccc gtcccccgac
     2521 ccgcaccctc cttcctcagg gcacttacta agggaggggt ctccctctcc atctccccag
     2581 tggcctcccc gcctccaacc ctgcctgcgg cctccccccg tcgcccaccc cacgtctcct
     2641 ggccactgag acacaaacct atttatttct aggcctggag aaaggagatc ggactggggt
     2701 tcccggtggg gcgccaggat ggctcctggg ggtgctcctg ccgccttcct tcacggcact
     2761 tacaaccggc gggaccccca gggaccaccc ctcagggcgc ccccccaccc ccgcccggtc
     2821 cacctagacc cccacgtttg gagattcaaa acttctgtct tcgtcctctc ccccgagccc
     2881 cctctcccaa atttttaaag cactttttag attttttttt ctctttcctc cttaaaaaca
     2941 aaatttatat atagatatat atatatatat aaataatata cttttcctca gaggagcagg
     3001 caacagtgtg ggataaacag agtcacgatc agaggaaccc cagggtctgg tgatggcagg
     3061 gatgggggga gagagagaaa atccacaaat tccaatgtca caaaagcaat aaaacaaact
     3121 agaaaaaaaa aaggttttac aaaatgaaag gaaggaaaaa aaaaaaggca accaaccaca
     3181 ttagaagtct tggcactttg taacggaacg ggtactacac tttatcttaa ttcttaattt
     3241 aaaaacatgt ttacaagtta caaccaactt ctatgaaaag ttgaaaagac aaaaaaaaaa
     3301 aaaaaaagcg agcgagagag agagcgagag agagagcgag agcagaagaa attcctaaaa
     3361 gtcgatttat ttttgtacaa aataataaaa aaaaaaaccc accacaaacg tagaatccac
     3421 ttctgttccc caaaaagcga gaaggggggt tcaggaggaa gccatcgcag gggacctggg
     3481 agacgccccg aggtgtttgt gcttcacccc cagacgtcag cctcgaaggc aggactgtgg
     3541 ggtgttcgtg ctgtgttccc cccgctcccc ctttctgtcc ccttttttgg ttctgacgtg
     3601 aagaggtctt agcgcccgct tctgtccacg gggtctctcc ttcctcctcc ctagctcagg
     3661 gatgggcctt ccagccggag caccccgatc cccatccggc accccccaat cccccaacac
     3721 gcctgtccct cccgcatggc caccaaggag ctggaccttg gatgcgccta ccctgctgag
     3781 gtgggtgaca ggggcccccc acctccaggg ccttagaacc accgcccctc tccccacccc
     3841 aggcacccct ctttttactc aaaggcactg actgtaatcc agggggactg ggacctgcct
     3901 ccccccaacc tctggctccc acaaggcccg gtgttgaccg agccacaggc cacggacagg
     3961 ggccggggtt ggggagacta tgtcgccaga tgccaggacg ccctcacccc gtttgcatat
     4021 gcaatgctag catgggaccc cgaaaataga cgctctgctg cactgagact tcttgtcaat
     4081 gcccaaccgg cgggggggtg tctccctgcc cccgaccccc ccataccccc ttctctgtga
     4141 cacacacatc ttctcgtctc tttttctttc attgttaaag ggaagctttt taagaaggca
     4201 attttcatat tgtttctaca ggatggtttt ggttcccttc ccttcccacc cccccttaag
     4261 cctgtcagcc ccctccaaat gtctcaggat cccccctctc ccctggggct gggtgacagc
     4321 accccggctg cgttcacacc ccagtgtcac agggcgagct gttctggaga gaaaaccatc
     4381 tgtcgtggct gagcggggag cttgaacacc caggccaggg acacccctcc ccagctccca
     4441 gagaggcccc ctgaggggtg agccctcttt ccaccttccc ctatccatgc accccctcgc
     4501 aataaaacca actctaaaat cacagctgtc gtcctagcca gtgggggcga ccggacttgg
     4561 ggggtggagc cctctgggac ttccgtagga acaagggctg cggcccaccg cgacacttac
     4621 acagacctcg gggattgcac taaaccctcg ttcctagctc cgcactcagc ttcgcctgtc
     4681 ctgcccgccc actttgcctt aactacccgc ccgtcctggg ggccacagcc tctgcatggg
     4741 cccagagccg ggaccccccc agcccagccc cgccctcccc agactccgcg caatcacata
     4801 ctgtatatag acgtgaatcg attttatttt tattctttaa attaaggtcg tgataaagtg
     4861 ttgccaaaga tacctgctga attctcgcgt ttcaggaaac aaacaaacaa aaaaaaatga
     4921 tatttgagga gggtcgtgtt gactccatat gaaaggacac agctcaaagc ttttttgttt
     4981 ggttgtttgg ggttttttgt gttttctttt tttggggtgt ttttttttta actgcctggt
     5041 acaaaaaaaa aaagagaaaa aaaaaaaaga aaaacaatgc gaaattgtta tttccattct
     5101 catggtgaag ttgcgtggac gcgtgtgtgc gtgtgtgcaa gagagcggga gtgaggtcca
     5161 ggctggggtt ggggggcttc aggcgggggc gcccgggggc cggggaggtg gccgggccgg
     5221 agcccccgtc tgcagtgccc cccagcctgc cgggcccagg agagagagag aagcatcttt
     5281 gctactagct gttgctgcta cctgcctctg ccccccgacg ccccccgcct tttgagatta
     5341 aggaaaaaaa aaaaaagtca aaaaagtttt taaaaatgaa aaaaaaaaat tataaaccag
     5401 tgaatgtaaa atgccggagc aggcccggcc tggcatgggt gtggacctgc agccaggcag
     5461 gctcgagcgg gcgataccaa agtctgcccc cccaccattg tggccatgca gtcctgtcac
     5521 tgtctttttg cttccttccg aggggggtcc cccagcctct tccagggtct tcccctggaa
     5581 gtgggcggct gcagggaagg tgggggacag gggtctttgc acgattcaga ccccggggcc
     5641 gtggcaggag cggtcacctc acaggtggtg acactgaggc aggggcctcg gggtgccccc
     5701 tcccgcccgg caaccagaat ggttggaggc aagacagaga gaatgaaagg aaaaacagaa
     5761 gaaaaaaaaa tattaaaaac caacaaaaaa agcaaaaatc ctattttttg agaaagaaag
     5821 atatttatat ttgcagtttt attttaaaaa gttatttaag ttgaagcagc cttcctggag
     5881 gtgggggggg gggggtggtg ggtggctggc gcaggacggg tcaggggcct ggaggctggg
     5941 ggtgccccag gagctacaac ctcagagtta agactagctc gcattaaata catagattta
     6001 cggggggggg gggggggggc cgggcccagg gggtggaggg ggccagggag acccccatcc
     6061 ctcgccgggg ctgcctggag gctgtggacc aggatccgat gcccaggtcc cgccccccac
     6121 cccaccccag gcccagaatc gaggtgcctt ggactttgga ggggccaggc ctggtgaatg
     6181 gggggcgggg cggcgccctc agggtacaga gcacagacag atagacattc cagagactgt
     6241 attgagagtc tttataaagt gtgggagatt taaaaaaaaa aaaaactgat aaaaatgcac
     6301 tttttgggag tggggaggga gaagctttaa aagtaataaa aaacaaacaa aaacacaaaa
     6361 gatgaaaaaa caaaaaaatt catttttctt gtacataaaa aaaaaaaaag aaccactaaa
     6421 cgcagcctgt tacgacc
//
