LOCUS       NM_019589               8195 bp    mRNA    linear   PRI 20-SEP-2024
DEFINITION  Homo sapiens YLP motif containing 1 (YLPM1), transcript variant 1,
            mRNA.
ACCESSION   NM_019589 XM_930487 XM_940570
VERSION     NM_019589.3
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 8195)
  AUTHORS   Benz,C., Ali,M., Krystkowiak,I., Simonetti,L., Sayadi,A.,
            Mihalic,F., Kliche,J., Andersson,E., Jemth,P., Davey,N.E. and
            Ivarsson,Y.
  TITLE     Proteome-scale mapping of binding sites in the unstructured regions
            of the human proteome
  JOURNAL   Mol Syst Biol 18 (1), e10584 (2022)
   PUBMED   35044719
REFERENCE   2  (bases 1 to 8195)
  AUTHORS   Huttlin,E.L., Bruckner,R.J., Navarrete-Perea,J., Cannon,J.R.,
            Baltier,K., Gebreab,F., Gygi,M.P., Thornock,A., Zarraga,G., Tam,S.,
            Szpyt,J., Gassaway,B.M., Panov,A., Parzen,H., Fu,S., Golbazi,A.,
            Maenpaa,E., Stricker,K., Guha Thakurta,S., Zhang,T., Rad,R.,
            Pan,J., Nusinow,D.P., Paulo,J.A., Schweppe,D.K., Vaites,L.P.,
            Harper,J.W. and Gygi,S.P.
  TITLE     Dual proteome-scale networks reveal cell-specific remodeling of the
            human interactome
  JOURNAL   Cell 184 (11), 3022-3040 (2021)
   PUBMED   33961781
REFERENCE   3  (bases 1 to 8195)
  AUTHORS   Yadav,L., Tamene,F., Goos,H., van Drogen,A., Katainen,R.,
            Aebersold,R., Gstaiger,M. and Varjosalo,M.
  TITLE     Systematic Analysis of Human Protein Phosphatase Interactions and
            Dynamics
  JOURNAL   Cell Syst 4 (4), 430-444 (2017)
   PUBMED   28330616
REFERENCE   4  (bases 1 to 8195)
  AUTHORS   Baltz,A.G., Munschauer,M., Schwanhausser,B., Vasile,A.,
            Murakawa,Y., Schueler,M., Youngs,N., Penfold-Brown,D., Drew,K.,
            Milek,M., Wyler,E., Bonneau,R., Selbach,M., Dieterich,C. and
            Landthaler,M.
  TITLE     The mRNA-bound proteome and its global occupancy profile on
            protein-coding transcripts
  JOURNAL   Mol Cell 46 (5), 674-690 (2012)
   PUBMED   22681889
REFERENCE   5  (bases 1 to 8195)
  AUTHORS   Esteves,S.L., Domingues,S.C., da Cruz e Silva,O.A., Fardilha,M. and
            da Cruz e Silva,E.F.
  TITLE     Protein phosphatase 1alpha interacting proteins in the human brain
  JOURNAL   OMICS 16 (1-2), 3-17 (2012)
   PUBMED   22321011
REFERENCE   6  (bases 1 to 8195)
  AUTHORS   Kahle,J.J., Gulbahce,N., Shaw,C.A., Lim,J., Hill,D.E.,
            Barabasi,A.L. and Zoghbi,H.Y.
  TITLE     Comparison of an expanded ataxia interactome with patient medical
            records reveals a relationship between macular degeneration and
            ataxia
  JOURNAL   Hum Mol Genet 20 (3), 510-527 (2011)
   PUBMED   21078624
REFERENCE   7  (bases 1 to 8195)
  AUTHORS   Sowa,M.E., Bennett,E.J., Gygi,S.P. and Harper,J.W.
  TITLE     Defining the human deubiquitinating enzyme interaction landscape
  JOURNAL   Cell 138 (2), 389-403 (2009)
   PUBMED   19615732
REFERENCE   8  (bases 1 to 8195)
  AUTHORS   Ulke-Lemee,A., Trinkle-Mulcahy,L., Chaulk,S., Bernstein,N.K.,
            Morrice,N., Glover,M., Lamond,A.I. and Moorhead,G.B.
  TITLE     The nuclear PP1 interacting protein ZAP3 (ZAP) is a putative
            nucleoside kinase that complexes with SAM68, CIA, NF110/45, and
            HNRNP-G
  JOURNAL   Biochim Biophys Acta 1774 (10), 1339-1350 (2007)
   PUBMED   17890166
  REMARK    GeneRIF: ZAP3 is a putative nucleoside kinase that targets protein
            phosphatase-1 through its highly conserved carboxy-terminal RVRW
            sequence.
REFERENCE   9  (bases 1 to 8195)
  AUTHORS   Armstrong,L., Lako,M., van Herpe,I., Evans,J., Saretzki,G. and
            Hole,N.
  TITLE     A role for nucleoprotein Zap3 in the reduction of telomerase
            activity during embryonic stem cell differentiation
  JOURNAL   Mech Dev 121 (12), 1509-1522 (2004)
   PUBMED   15511642
REFERENCE   10 (bases 1 to 8195)
  AUTHORS   Sherrington,R., Rogaev,E.I., Liang,Y., Rogaeva,E.A., Levesque,G.,
            Ikeda,M., Chi,H., Lin,C., Li,G., Holman,K., Tsuda,T., Mar,L.,
            Foncin,J.F., Bruni,A.C., Montesi,M.P., Sorbi,S., Rainero,I.,
            Pinessi,L., Nee,L., Chumakov,I., Pollen,D., Brookes,A., Sanseau,P.,
            Polinsky,R.J., Wasco,W., Da Silva,H.A., Haines,J.L.,
            Perkicak-Vance,M.A., Tanzi,R.E., Roses,A.D., Fraser,P.E.,
            Rommens,J.M. and St George-Hyslop,P.H.
  TITLE     Cloning of a gene bearing missense mutations in early-onset
            familial Alzheimer's disease
  JOURNAL   Nature 375 (6534), 754-760 (1995)
   PUBMED   7596406
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC007956.5, AK095760.1, DB096717.1, AK090435.1, BC007792.1 and
            BX102033.1.
            
            On Nov 23, 2018 this sequence version replaced NM_019589.2.
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. There are no publicly available
            full-length transcripts representing this RefSeq; it is supported
            by partial transcript data and by protein evidence in
            PMID:17890166.
            
            ##Evidence-Data-START##
            RNAseq introns :: single sample supports all introns SAMEA1965299,
                              SAMEA1966682 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000325680.12/ ENSP00000324463.7
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-50                AC007956.5         146282-146331
            51-1284             AK095760.1         1-1234
            1285-1625           DB096717.1         221-561
            1626-5521           AK090435.1         332-4227
            5522-7039           BC007792.1         69-1586
            7040-7664           AC007956.5         219129-219753
            7665-8187           BX102033.1         14-536              c
            8188-8195           AC007956.5         220277-220284
FEATURES             Location/Qualifiers
     source          1..8195
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="14"
                     /map="14q24.3"
     gene            1..8195
                     /gene="YLPM1"
                     /gene_synonym="C14orf170; PPP1R169; ZAP113; ZAP3"
                     /note="YLP motif containing 1"
                     /db_xref="GeneID:56252"
                     /db_xref="HGNC:HGNC:17798"
                     /db_xref="MIM:619766"
     exon            1..1047
                     /gene="YLPM1"
                     /gene_synonym="C14orf170; PPP1R169; ZAP113; ZAP3"
                     /inference="alignment:Splign:2.1.0"
     CDS             175..6615
                     /gene="YLPM1"
                     /gene_synonym="C14orf170; PPP1R169; ZAP113; ZAP3"
                     /note="isoform 1 is encoded by transcript variant 1; YLP
                     motif-containing protein 1; nuclear protein ZAP3; protein
                     phosphatase 1, regulatory subunit 169"
                     /codon_start=1
                     /product="YLP motif-containing protein 1 isoform 1"
                     /protein_id="NP_062535.2"
                     /db_xref="CCDS:CCDS45135.1"
                     /db_xref="GeneID:56252"
                     /db_xref="HGNC:HGNC:17798"
                     /db_xref="MIM:619766"
                     /translation="MYPNWGRYGGSSHYPPPPVPPPPPVALPEASPGPGYSSSTTPAA
                     PSSSGFMSFREQHLAQLQQLQQMHQKQMQCVLQPHHLPPPPLPPPPVMPGGGYGDWQP
                     PPPPMPPPPGPALSYQKQQQYKHQMLHHQRDGPPGLVPMELESPPESPPVPPGSYMPP
                     SQSYMPPPQPPPSYYPPTSSQPYLPPAQPSPSQSPPSQSYLAPTPSYSSSSSSSQSYL
                     SHSQSYLPSSQASPSRPSQGHSKSQLLAPPPPSAPPGNKTTVQQEPLESGAKNKSTEQ
                     QQAAPEPDPSTMTPQEQQQYWYRQHLLSLQQRTKVHLPGHKKGPVVAKDTPEPVKEEV
                     TVPATSQVPESPSSEEPPLPPPNEEVPPPLPPEEPQSEDPEEDARLKQLQAAAAHWQQ
                     HQQHRVGFQYQGIMQKHTQLQQILQQYQQIIQPPPHIQTMSVDMQLRHYEMQQQQFQH
                     LYQEWEREFQLWEEQLHSYPHKDQLQEYEKQWKTWQGHMKATQSYLQEKVNSFQNMKN
                     QYMGNMSMPPPFVPYSQMPPPLPTMPPPVLPPSLPPPVMPPALPATVPPPGMPPPVMP
                     PSLPTSVPPPGMPPSLSSAGPPPVLPPPSLSSAGPPPVLPPPSLSSTAPPPVMPLPPL
                     SSATPPPGIPPPGVPQGIPPQLTAAPVPPASSSQSSQVPEKPRPALLPTPVSFGSAPP
                     TTYHPPLQSAGPSEQVNSKAPLSKSALPYSSFSSDQGLGESSAAPSQPITAVKDMPVR
                     SGGLLPDPPRSSYLESPRGPRFDGPRRFEDLGSRCEGPRPKGPRFEGNRPDGPRPRYE
                     GHPAEGTKSKWGMIPRGPASQFYITPSTSLSPRQSGPQWKGPKPAFGQQHQQQPKSQA
                     EPLSGNKEPLADTSSNQQKNFKMQSAAFSIAADVKDVKAAQSNENLSDSQQEPPKSEV
                     SEGPVEPSNWDQNVQSMETQIDKAQAVTQPVPLANKPVPAQSTFPSKTGGMEGGTAVA
                     TSSLTADNDFKPVGIGLPHSENNQDKGLPRPDNRDNRLEGNRGNSSSYRGPGQSRMED
                     TRDKGLVNRGRGQAISRGPGLVKQEDFRDKMMGRREDSREKMNRGEGSRDRGLVRPGS
                     SREKVPGGLQGSQDRGAAGSRERGPPRRAGSQERGPLRRAGSRERIPPRRAGSRERGP
                     PRGPGSRERGLGRSDFGRDRGPFRPEPGDGGEKMYPYHRDEPPRAPWNHGEERGHEEF
                     PLDGRNAPMERERLDDWDRERYWRECERDYQDDTLELYNREDRFSAPPSRSHDGDRRG
                     PWWDDWERDQDMDEDYNREMERDMDRDVDRISRPMDMYDRSLDNEWDRDYGRPLDEQE
                     SQFRERDIPSLPPLPPLPPLPPLDRYRDDRWREERNREHGYDRDFRDRGELRIREYPE
                     RGDTWREKRDYVPDRMDWERERLSDRWYPSDVDRHSPMAEHMPSSHHSSEMMGSDASL
                     DSDQGLGGVMVLSQRQHEIILKAAQELKMLREQKEQLQKMKDFGSEPQMADHLPPQES
                     RLQNTSSRPGMYPPPGSYRPPPPMGKPPGSIVRPSAPPARSSVPVTRPPVPIPPPPPP
                     PPLPPPPPVIKPQTSAVEQERWDEDSFYGLWDTNDEQGLNSEFKSETAAIPSAPVLPP
                     PPVHSSIPPPGPVPMGMPPMSKPPPVQQTVDYGHGRDISTNKVEQIPYGERITLRPDP
                     LPERSTFETEHAGQRDRYDRERDREPYFDRQSNVIADHRDFKRDRETHRDRDRDRGVI
                     DYDRDRFDRERRPRDDRAQSYRDKKDHSSSRRGGFDRPSYDRKSDRPVYEGPSMFGGE
                     RRTYPEERMPLPAPSLSHQPPPAPRVEKKPESKNVDDILKPPGRESRPERIVVIMRGL
                     PGSGKTHVAKLIRDKEVEFGGPAPRVLSLDDYFITEVEKEEKDPDSGKKVKKKVMEYE
                     YEAEMEETYRTSMFKTFKKTLDDGFFPFIILDAINDRVRHFDQFWSAAKTKGFEVYLA
                     EMSADNQTCGKRNIHGRKLKEINKMADHWETAPRHMMRLDIRSLLQDAAIEEVEMEDF
                     DANIEEQKEEKKDAEEEESELGYIPKSKWEMDTSEAKLDKLDGLRTGTKRKRDWEAIA
                     SRMEDYLQLPDDYDTRASEPGKKRVRWADLEEKKDADRKRAIGFVVGQTDWEKITDES
                     GHLAEKALNRTKYI"
     exon            1048..1284
                     /gene="YLPM1"
                     /gene_synonym="C14orf170; PPP1R169; ZAP113; ZAP3"
                     /inference="alignment:Splign:2.1.0"
     exon            1285..1464
                     /gene="YLPM1"
                     /gene_synonym="C14orf170; PPP1R169; ZAP113; ZAP3"
                     /inference="alignment:Splign:2.1.0"
     exon            1465..2456
                     /gene="YLPM1"
                     /gene_synonym="C14orf170; PPP1R169; ZAP113; ZAP3"
                     /inference="alignment:Splign:2.1.0"
     exon            2457..4574
                     /gene="YLPM1"
                     /gene_synonym="C14orf170; PPP1R169; ZAP113; ZAP3"
                     /inference="alignment:Splign:2.1.0"
     exon            4575..4695
                     /gene="YLPM1"
                     /gene_synonym="C14orf170; PPP1R169; ZAP113; ZAP3"
                     /inference="alignment:Splign:2.1.0"
     exon            4696..5113
                     /gene="YLPM1"
                     /gene_synonym="C14orf170; PPP1R169; ZAP113; ZAP3"
                     /inference="alignment:Splign:2.1.0"
     exon            5114..5206
                     /gene="YLPM1"
                     /gene_synonym="C14orf170; PPP1R169; ZAP113; ZAP3"
                     /inference="alignment:Splign:2.1.0"
     exon            5207..5402
                     /gene="YLPM1"
                     /gene_synonym="C14orf170; PPP1R169; ZAP113; ZAP3"
                     /inference="alignment:Splign:2.1.0"
     exon            5403..5521
                     /gene="YLPM1"
                     /gene_synonym="C14orf170; PPP1R169; ZAP113; ZAP3"
                     /inference="alignment:Splign:2.1.0"
     exon            5522..5676
                     /gene="YLPM1"
                     /gene_synonym="C14orf170; PPP1R169; ZAP113; ZAP3"
                     /inference="alignment:Splign:2.1.0"
     exon            5677..5739
                     /gene="YLPM1"
                     /gene_synonym="C14orf170; PPP1R169; ZAP113; ZAP3"
                     /inference="alignment:Splign:2.1.0"
     exon            5740..5859
                     /gene="YLPM1"
                     /gene_synonym="C14orf170; PPP1R169; ZAP113; ZAP3"
                     /inference="alignment:Splign:2.1.0"
     exon            5860..6036
                     /gene="YLPM1"
                     /gene_synonym="C14orf170; PPP1R169; ZAP113; ZAP3"
                     /inference="alignment:Splign:2.1.0"
     exon            6037..6120
                     /gene="YLPM1"
                     /gene_synonym="C14orf170; PPP1R169; ZAP113; ZAP3"
                     /inference="alignment:Splign:2.1.0"
     exon            6121..6204
                     /gene="YLPM1"
                     /gene_synonym="C14orf170; PPP1R169; ZAP113; ZAP3"
                     /inference="alignment:Splign:2.1.0"
     exon            6205..6285
                     /gene="YLPM1"
                     /gene_synonym="C14orf170; PPP1R169; ZAP113; ZAP3"
                     /inference="alignment:Splign:2.1.0"
     exon            6286..6337
                     /gene="YLPM1"
                     /gene_synonym="C14orf170; PPP1R169; ZAP113; ZAP3"
                     /inference="alignment:Splign:2.1.0"
     exon            6338..6468
                     /gene="YLPM1"
                     /gene_synonym="C14orf170; PPP1R169; ZAP113; ZAP3"
                     /inference="alignment:Splign:2.1.0"
     exon            6469..6651
                     /gene="YLPM1"
                     /gene_synonym="C14orf170; PPP1R169; ZAP113; ZAP3"
                     /inference="alignment:Splign:2.1.0"
     exon            6652..8195
                     /gene="YLPM1"
                     /gene_synonym="C14orf170; PPP1R169; ZAP113; ZAP3"
                     /inference="alignment:Splign:2.1.0"
     regulatory      7021..7026
                     /regulatory_class="polyA_signal_sequence"
                     /gene="YLPM1"
                     /gene_synonym="C14orf170; PPP1R169; ZAP113; ZAP3"
                     /note="hexamer: AATAAA"
     regulatory      7034..7039
                     /regulatory_class="polyA_signal_sequence"
                     /gene="YLPM1"
                     /gene_synonym="C14orf170; PPP1R169; ZAP113; ZAP3"
                     /note="hexamer: GATAAA"
     polyA_site      7044
                     /gene="YLPM1"
                     /gene_synonym="C14orf170; PPP1R169; ZAP113; ZAP3"
                     /note="major polyA site"
     polyA_site      7067
                     /gene="YLPM1"
                     /gene_synonym="C14orf170; PPP1R169; ZAP113; ZAP3"
                     /note="major polyA site"
     regulatory      7132..7137
                     /regulatory_class="polyA_signal_sequence"
                     /gene="YLPM1"
                     /gene_synonym="C14orf170; PPP1R169; ZAP113; ZAP3"
                     /note="hexamer: ATTAAA"
     polyA_site      7158
                     /gene="YLPM1"
                     /gene_synonym="C14orf170; PPP1R169; ZAP113; ZAP3"
     regulatory      8151..8156
                     /regulatory_class="polyA_signal_sequence"
                     /gene="YLPM1"
                     /gene_synonym="C14orf170; PPP1R169; ZAP113; ZAP3"
                     /note="hexamer: TATAAA"
     regulatory      8164..8169
                     /regulatory_class="polyA_signal_sequence"
                     /gene="YLPM1"
                     /gene_synonym="C14orf170; PPP1R169; ZAP113; ZAP3"
                     /note="hexamer: ATTAAA"
     polyA_site      8172
                     /gene="YLPM1"
                     /gene_synonym="C14orf170; PPP1R169; ZAP113; ZAP3"
     polyA_site      8195
                     /gene="YLPM1"
                     /gene_synonym="C14orf170; PPP1R169; ZAP113; ZAP3"
ORIGIN      
        1 cttcccggtc gcgggcccag ctcgggagcg ccggcgcact ggcgcgctcc gtttacacgc
       61 tccggggcct gtaggcgccg cgagttccgg ctgtcgccgt cgccgccgcg gctcctggag
      121 gtcggttgcg acgagtaacg gcgccaggac gagccctgcg ccttcttttt cgatatgtac
      181 ccgaattggg gccggtatgg cgggagcagc cactatccgc cgccaccggt cccaccgccg
      241 ccgccagtgg cgcttcctga ggcctcgccg gggcccgggt actcgagctc gacgactccc
      301 gcggccccct cctcctcggg cttcatgagc ttccgcgaac agcacttggc gcagctccag
      361 cagctgcagc agatgcacca gaagcaaatg cagtgcgtgc ttcagcccca ccaccttcct
      421 ccgccccctc tgccgccccc gccagtgatg ccggggggcg gctacggaga ctggcagccg
      481 ccaccgccac cgatgccccc gccacccggg ccggccctca gctatcagaa gcagcagcag
      541 tacaaacacc agatgctcca ccaccaacga gacgggcctc ctggtttggt tccaatggag
      601 ctggaatccc cccctgaatc tccccctgtg ccgcctgggt cctatatgcc cccatctcag
      661 tcttacatgc ccccacctca gccgccaccc tcttactacc ccccgacctc atctcagccc
      721 tacctgcctc ctgctcagcc gtccccttcg cagtccccac cttcccaatc ctacctggcg
      781 cccacccctt cttactcatc ctcctcctct tcctcgcaat cctatttgag ccattcccag
      841 tcctacttgc cctcttctca ggcatctcct tcccgcccct cccagggcca ttctaaatcc
      901 caactactag ctccaccacc accgtccgcc ccccctggaa ataagacaac tgtccagcaa
      961 gagcctttgg agagtggggc caaaaacaag agtactgaac agcagcaagc cgcccctgag
     1021 ccagatccct ctacgatgac tccacaggaa cagcagcagt attggtatcg acagcacttg
     1081 cttagtttgc aacagaggac aaaagttcat ttgccaggac acaaaaaggg tcctgtggta
     1141 gcaaaggata caccagagcc ggtaaaagaa gaagttacag tacctgccac cagtcaagtt
     1201 ccagaatctc cttcttctga ggagccccca ttgccacctc caaatgagga agtgccacct
     1261 cctctcccac ctgaggaacc ccagtctgag gacccagaag aagatgccag gttaaagcag
     1321 ttgcaggctg cagcagcaca ctggcagcag caccagcagc atcgagtcgg tttccagtat
     1381 cagggaataa tgcagaagca cactcagtta cagcagattc tacaacagta tcagcagatt
     1441 atacagcccc caccacatat acagaccatg tctgtagata tgcagctgcg gcattatgag
     1501 atgcagcagc aacagtttca acatctttac caagaatggg agcgagagtt tcagctatgg
     1561 gaggaacaac tccattccta tcctcataaa gatcagcttc aggagtatga gaagcagtgg
     1621 aaaacatggc agggacatat gaaagccact cagagctatc tccaggagaa agtcaattca
     1681 tttcagaaca tgaagaacca gtatatgggg aacatgtcaa tgccacctcc ttttgttcca
     1741 tattctcaga tgcctccacc tctacctaca atgccccctc cagtgttgcc tccttcattg
     1801 ccaccaccag tgatgccccc tgccctccct gctacagtgc caccacctgg catgccccca
     1861 cctgttatgc caccttctct accaacctct gttcccccac cagggatgcc tccttctctc
     1921 tcttctgcag ggccaccacc agttctcccc ccaccttccc tgtcttctgc agggccacca
     1981 ccagttcttc ccccaccatc tctctcttca acagcacctc cacctgtcat gcccctccca
     2041 ccattgtctt cagctacacc tcctccagga atacctcccc ctggagttcc acaagggata
     2101 cctcctcagt taacagcagc cccagttcca ccagcctcca gttcacagag ctcgcaagtt
     2161 ccagagaaac ctagaccagc actgcttcct actcctgtgt cttttggttc tgccccaccg
     2221 acaacttacc atcctccgtt gcaatcagct ggtccatcag aacaagtgaa ttcaaaagct
     2281 cctttgagca agtctgctct gccatacagt tcattctcat ctgatcaagg acttggggag
     2341 tcttcagctg ctccatctca gccaatcact gcagtgaagg acatgccagt gagatcaggt
     2401 ggcctgcttc cagatcctcc tagaagtagt tacttggaaa gtccaagagg cccaagattt
     2461 gatggtcctc gaagatttga ggatttaggg tcaaggtgtg aaggaccgag acccaaaggg
     2521 cctcgttttg aaggaaatcg ccccgatggg ccaagaccca gatatgaagg tcacccagca
     2581 gagggcacta aaagcaagtg gggaatgatt ccccgggggc cagcatctca attttatatt
     2641 acccccagta catccctaag tcctcgacag agtggaccac agtggaaagg ccccaaacca
     2701 gcttttggac agcagcatca gcagcaacct aagtcacaag cagaacctct ttcaggaaac
     2761 aaagaaccat tagcagacac cagtagtaac cagcagaaga attttaaaat gcaatcagct
     2821 gcattttcca ttgctgcaga tgtaaaggat gtcaaggcgg ctcagtcaaa tgagaatcta
     2881 agcgactctc aacaagagcc acctaaaagt gaagtctcgg aagggcccgt agagccctct
     2941 aattgggacc agaatgttca aagtatggag actcaaatcg acaaagccca agctgttact
     3001 cagcctgtac cccttgcgaa taagcctgta cctgctcaat ctacttttcc ttcaaaaaca
     3061 ggggggatgg agggaggaac agcagtagca acatcatcat taacagcaga taatgatttt
     3121 aaacctgtgg gtattggtct accccattca gaaaacaacc aagataaagg cctgcctcgg
     3181 ccagataata gagataatag attagaaggc aatagaggca acagctcatc ttacagaggt
     3241 cctgggcaaa gcagaatgga agacacacgg gataaaggtc tagtaaacag aggtcgcggc
     3301 caggcaatca gtcgaggccc aggattggtc aagcaagaag actttcggga taagatgatg
     3361 ggtagaagag aagatagtcg agagaagatg aacagaggag aaggtagccg ggacagaggg
     3421 ttggtgaggc ctggaagcag tcgggagaaa gtgccaggtg gtcttcaagg gagccaggac
     3481 aggggtgcag ctggcagccg agaaagggga ccacctcgga gggctggcag tcaggagagg
     3541 ggacctcttc gaagggctgg gagtagagag agaataccac cccgaagagc tgggagcagg
     3601 gagagaggac cacctcgagg gcctggcagt cgagaaaggg gactgggaag atcagatttt
     3661 ggtcgtgata gaggtccatt cagaccagaa ccaggagatg gtggggaaaa aatgtatcca
     3721 tatcaccggg atgagcctcc tagggctcca tggaaccatg gagaagagcg agggcatgaa
     3781 gagtttccat tagatggtag aaatgctcca atggaacgag aaagactcga tgactgggat
     3841 agagagagat actggagaga atgtgaacgt gactatcaag atgatacact agagctctat
     3901 aacagagagg acaggttctc agcaccacca tctcggtctc atgatggaga taggcgaggc
     3961 ccttggtggg atgattggga gagagaccag gatatggatg aggactacaa tagggaaatg
     4021 gaaagggaca tggacaggga tgtggatcgg atttcaagac ctatggatat gtatgataga
     4081 agtttggata atgagtggga cagagattat gggagaccac tggatgaaca agaatcacag
     4141 tttcgtgaac gggatattcc atctcttcca cctttaccgc ccctcccacc tcttccacct
     4201 ttggatagat atcgggatga tagatggaga gaagaaagaa atcgagagca tgggtatgat
     4261 cgagatttcc gtgatagggg tgagttgagg attcgagagt atccagaaag aggagataca
     4321 tggcgggaaa agcgagatta tgttcctgac agaatggact gggaaagaga acggttgtca
     4381 gacagatggt acccatctga tgtggataga cattccccca tggcggaaca tatgccctcc
     4441 tcacatcatt cctcagaaat gatggggtcc gatgcaagct tagactctga ccaaggcctt
     4501 ggaggggtaa tggttctcag tcagaggcag catgaaatca ttttgaaagc tgcacaagaa
     4561 ctgaaaatgc ttcgggaaca gaaagaacag cttcaaaaga tgaaagactt cgggtctgag
     4621 ccacagatgg ctgaccatct accacctcag gaatcaagat tgcagaatac atcttcaaga
     4681 cctggaatgt atccgcctcc agggtcgtat agacctcccc ctcctatggg caaaccacca
     4741 ggttcaattg taagaccctc tgctccacca gcaagatcat ctgttcctgt gaccaggcca
     4801 cctgtcccaa taccaccacc tccacctcct ccacctctac ctcctcctcc tccagtgata
     4861 aagccacaaa cttcagctgt agaacaggaa cgatgggatg aagattcttt ctatgggctc
     4921 tgggatacaa atgatgaaca aggactgaat tcagaattta agtcagaaac tgcagcaatt
     4981 ccatctgctc cagtattacc acccccacct gttcactctt ccattccccc tcctggccca
     5041 gtgcctatgg gtatgccacc aatgtccaag ccaccaccag tacaacagac tgttgattat
     5101 ggccatggcc gagatatatc cactaataaa gttgaacaga taccttatgg agaaagaata
     5161 actctacgcc cagatccact acctgaaaga tcaacttttg agacagagca tgcaggccaa
     5221 cgtgatcgtt atgatagaga aagagatcgt gagccttatt ttgatcgtca aagtaatgtc
     5281 atagcagatc atcgagattt taaaagggat cgtgagacac atagagatcg agaccgggat
     5341 cgtggtgtta ttgactatga ccgggatcga tttgacagag aacgccgacc ccgagatgat
     5401 agagctcagt catatcgaga caaaaaagac cattcctcat ccagaagagg gggttttgat
     5461 aggccatcct atgaccggaa gtctgaccga ccagtctatg aaggaccatc catgtttgga
     5521 ggagaacgaa ggacttatcc tgaggagcga atgcctctgc cagctccttc actgagccac
     5581 cagcctcctc cagctccacg agtcgagaag aagcctgaat caaagaatgt ggacgatatt
     5641 ttgaaaccac cgggccggga gagcagacct gagagaattg ttgttataat gagaggatta
     5701 cctggcagtg gaaagacaca tgttgcaaaa cttattcgag ataaggaggt agaatttgga
     5761 ggacctgcac ccagagttct aagcctggat gattacttca tcactgaagt ggaaaaagaa
     5821 gaaaaagatc cagattctgg aaagaaagtg aaaaagaagg taatggaata tgaatatgaa
     5881 gctgagatgg aggagactta ccgcaccagc atgttcaaaa ctttcaaaaa gactctggat
     5941 gatggctttt ttcccttcat catcctggat gccatcaatg acagagttag gcattttgac
     6001 cagttttgga gtgcagcaaa aaccaaggga tttgaggtat atttggctga aatgagtgca
     6061 gataaccaga cttgtggcaa gagaaatatt catggaagaa agcttaaaga aataaataag
     6121 atggctgatc actgggaaac tgcacctcgt cacatgatgc gtctagatat tcgttctttg
     6181 ctgcaagatg ctgctattga agaggtagag atggaagatt ttgatgcaaa tatcgaagaa
     6241 cagaaagaag aaaagaaaga tgcagaggaa gaggaaagcg aactgggtta cattccgaaa
     6301 agcaaatggg agatggacac atctgaggca aagctagaca agttggatgg cttgaggact
     6361 ggtactaaaa ggaaacgtga ctgggaggcc attgccagca gaatggagga ttatcttcag
     6421 ctccccgatg attatgatac tcgtgcttct gagcctggga agaagagggt cagatgggca
     6481 gacctggaag agaagaagga tgcagatagg aaaagggcca taggttttgt ggtcggacag
     6541 actgattggg agaagatcac agatgaaagt ggtcacctgg ctgaaaaagc cctcaatcga
     6601 accaaatata tatgagactt agtttttgaa cggagtcatt attcctctaa ggtggttcgc
     6661 tttgaggtgg tctgaagcca aggcctcgcg gagcttcttt gtgtgtcacc ttgcttccac
     6721 gtttcagttc ttgttttgtt tctactgctt tagttttttt taaagttctc cagtgtcccc
     6781 aagaggtatt agaatcttgc tgtacccaag caagacgtta atttttcttt taactgtttt
     6841 ggggagggag ggagtgatag cttaactgct gaagccaggc gggggtctgc tggaggattc
     6901 caacagagag tatttcctcc actgtacaat gtcacagact atctctatca tcattgcttt
     6961 gtggctgttt ctgtttttta ctgtatgtaa ctggtagctg attgtactag gattaaaaac
     7021 aataaacttt catgataaag ccgatgagat tcatgggcta tacagcatgg gcccttttct
     7081 cttgttttct taattttatt tttaattgct ttttaaatat ggtatgtcct aattaaatgc
     7141 tagctgaaca tcccaaaacc tttttttcat tgaatattat atggctcaat gattccgtag
     7201 cacatgttgt aaaacacagg gttcaaatga tgttcaaaac actcatcttt gttttatagc
     7261 tgatttctct atctttgtgt cttgaagact gaccaagttc aaatattcat cagttccctg
     7321 gagcatatcc attctgtaac atgatgcttt atttaaaaat tttttttgat cctctctctg
     7381 ttcttccctc tcttctttcc ttccttcttc ttttcacttt ctgcctttat gctgttaggt
     7441 ttttattttt tcctgatctg gctttgaatt ctggtagaca gaactgatgt attctgtgga
     7501 actcaagctt gttgccttca tttgaacttg aattgtggat ttttaaatga agattgcagg
     7561 gaaagagtat aaagatgcag agcactctgg catgtaacct ttaagcctgt caggttttca
     7621 agttcttgcc agattgttca ttactggaaa gcatggcctt ctgcacagaa tttcctctct
     7681 tgtggttaat accaggtgga acccagaaac atacagagat aaaacccaaa tattatttct
     7741 atgtaaacac agaaaaggga ctcttccctt tttcatcctg caaagaaaaa agtcatcttt
     7801 tagcatgaaa gaagatgaga gagccttctt cctcaagcat aatttgcatt ttgtaatcca
     7861 actcagtaat ttgtaaatgt gttcactgaa gacttcaata ttttgaaata ttctctttca
     7921 ggccacagat gaaaatcctt tacttttatg acctacatta aagactgtat gaatagagct
     7981 aatagttact agcatttgaa tagtatcact ttgggttcaa caaattgata ttatagtact
     8041 gaatacccct aatttaatgg aaattctaac aactttctgt acttttatct tccctgaaaa
     8101 tctgaatttt taagcaagtg actttaagtt cattaagtca atattgaatg tataaattgc
     8161 tacattaaat aacttctgct gtttgtagta tttaa
//
