LOCUS       NM_030818               1673 bp    mRNA    linear   PRI 03-APR-2024
DEFINITION  Homo sapiens YJU2 splicing factor homolog B (YJU2B), transcript
            variant 1, mRNA.
ACCESSION   NM_030818
VERSION     NM_030818.4
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 1673)
  AUTHORS   Luck,K., Kim,D.K., Lambourne,L., Spirohn,K., Begg,B.E., Bian,W.,
            Brignall,R., Cafarelli,T., Campos-Laborie,F.J., Charloteaux,B.,
            Choi,D., Cote,A.G., Daley,M., Deimling,S., Desbuleux,A., Dricot,A.,
            Gebbia,M., Hardy,M.F., Kishore,N., Knapp,J.J., Kovacs,I.A.,
            Lemmens,I., Mee,M.W., Mellor,J.C., Pollis,C., Pons,C.,
            Richardson,A.D., Schlabach,S., Teeking,B., Yadav,A., Babor,M.,
            Balcha,D., Basha,O., Bowman-Colin,C., Chin,S.F., Choi,S.G.,
            Colabella,C., Coppin,G., D'Amata,C., De Ridder,D., De Rouck,S.,
            Duran-Frigola,M., Ennajdaoui,H., Goebels,F., Goehring,L., Gopal,A.,
            Haddad,G., Hatchi,E., Helmy,M., Jacob,Y., Kassa,Y., Landini,S.,
            Li,R., van Lieshout,N., MacWilliams,A., Markey,D., Paulson,J.N.,
            Rangarajan,S., Rasla,J., Rayhan,A., Rolland,T., San-Miguel,A.,
            Shen,Y., Sheykhkarimli,D., Sheynkman,G.M., Simonovsky,E., Tasan,M.,
            Tejeda,A., Tropepe,V., Twizere,J.C., Wang,Y., Weatheritt,R.J.,
            Weile,J., Xia,Y., Yang,X., Yeger-Lotem,E., Zhong,Q., Aloy,P.,
            Bader,G.D., De Las Rivas,J., Gaudet,S., Hao,T., Rak,J.,
            Tavernier,J., Hill,D.E., Vidal,M., Roth,F.P. and Calderwood,M.A.
  TITLE     A reference map of the human binary protein interactome
  JOURNAL   Nature 580 (7803), 402-408 (2020)
   PUBMED   32296183
REFERENCE   2  (bases 1 to 1673)
  AUTHORS   Fragoza,R., Das,J., Wierbowski,S.D., Liang,J., Tran,T.N., Liang,S.,
            Beltran,J.F., Rivera-Erick,C.A., Ye,K., Wang,T.Y., Yao,L., Mort,M.,
            Stenson,P.D., Cooper,D.N., Wei,X., Keinan,A., Schimenti,J.C.,
            Clark,A.G. and Yu,H.
  TITLE     Extensive disruption of protein interactions by genetic variants
            across the allele frequency spectrum in human populations
  JOURNAL   Nat Commun 10 (1), 4141 (2019)
   PUBMED   31515488
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 1673)
  AUTHORS   Lammers,R., Gross,G., Mayr,U. and Collins,J.
  TITLE     Alternative mechanisms for gene activation induced by
            poly(rI).poly(rC) and Newcastle disease virus
  JOURNAL   Eur J Biochem 178 (1), 93-99 (1988)
   PUBMED   3203696
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BM547551.1 and BC002905.2.
            
            On Nov 22, 2018 this sequence version replaced NM_030818.3.
            
            Transcript Variant: This variant (1) encodes the longest isoform
            (a). Variants 1, 2, 3, and 4 all encode the same isoform (a).
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR3476690.965470.1,
                                           SRR3476690.961148.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA1965299, SAMEA1966682
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000221554.13/ ENSP00000221554.7
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-44                BM547551.1         31-74
            45-1673             BC002905.2         1-1629
FEATURES             Location/Qualifiers
     source          1..1673
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="19"
                     /map="19p13.13"
     gene            1..1673
                     /gene="YJU2B"
                     /gene_synonym="CCDC130"
                     /note="YJU2 splicing factor homolog B"
                     /db_xref="GeneID:81576"
                     /db_xref="HGNC:HGNC:28118"
     exon            1..60
                     /gene="YJU2B"
                     /gene_synonym="CCDC130"
                     /inference="alignment:Splign:2.1.0"
     exon            61..264
                     /gene="YJU2B"
                     /gene_synonym="CCDC130"
                     /inference="alignment:Splign:2.1.0"
     CDS             262..1452
                     /gene="YJU2B"
                     /gene_synonym="CCDC130"
                     /note="isoform a is encoded by transcript variant 1;
                     coiled-coil domain-containing protein 130; 9 kDa protein;
                     coiled-coil domain containing 130; probable splicing
                     factor YJU2B"
                     /codon_start=1
                     /product="probable splicing factor YJU2B isoform a"
                     /protein_id="NP_110445.1"
                     /db_xref="CCDS:CCDS12296.1"
                     /db_xref="GeneID:81576"
                     /db_xref="HGNC:HGNC:28118"
                     /translation="MGERKGVNKYYPPDFNPEKHGSLNRYHNSHPLRERARKLSQGIL
                     IIRFEMPYNIWCDGCKNHIGMGVRYNAEKKKVGNYYTTPIYRFRMKCHLCVNYIEMQT
                     DPANCDYVIVSGAQRKEERWDMADNEQVLTTEHEKKQKLETDAMFRLEHGEADRSTLK
                     KALPTLSHIQEAQSAWKDDFALNSMLRRRFREKKKAIQEEEERDQALQAKASLTIPLV
                     PETEDDRKLAALLKFHTLDSYEDKQKLKRTEIISRSWFPSAPGSASSSKVSGVLKKLA
                     QSRRTALATSPITVGDLGIVRRRSRDVPESPQHAADTPKSGEPRVPEEAAQDRPMSPG
                     DCPPETTETPKCSSPRGQEGSRQDKPLSPAGSSQEAADTPDTRHPCSLGSSLVADYSD
                     SESE"
     exon            265..318
                     /gene="YJU2B"
                     /gene_synonym="CCDC130"
                     /inference="alignment:Splign:2.1.0"
     exon            319..401
                     /gene="YJU2B"
                     /gene_synonym="CCDC130"
                     /inference="alignment:Splign:2.1.0"
     exon            402..457
                     /gene="YJU2B"
                     /gene_synonym="CCDC130"
                     /inference="alignment:Splign:2.1.0"
     exon            458..518
                     /gene="YJU2B"
                     /gene_synonym="CCDC130"
                     /inference="alignment:Splign:2.1.0"
     exon            519..661
                     /gene="YJU2B"
                     /gene_synonym="CCDC130"
                     /inference="alignment:Splign:2.1.0"
     exon            662..834
                     /gene="YJU2B"
                     /gene_synonym="CCDC130"
                     /inference="alignment:Splign:2.1.0"
     exon            835..973
                     /gene="YJU2B"
                     /gene_synonym="CCDC130"
                     /inference="alignment:Splign:2.1.0"
     exon            974..1673
                     /gene="YJU2B"
                     /gene_synonym="CCDC130"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1655..1660
                     /regulatory_class="polyA_signal_sequence"
                     /gene="YJU2B"
                     /gene_synonym="CCDC130"
                     /note="hexamer: ATTAAA"
     polyA_site      1673
                     /gene="YJU2B"
                     /gene_synonym="CCDC130"
                     /note="major polyA site"
ORIGIN      
        1 accgcgctct cagcgcgcac ttccgggcac ggtcagggcg tgacgtcggg aggagggcag
       61 acacgccgct ttttggatgc ctcctatgcc tggcgggagt cttgtctgag ctggcaccac
      121 cacacggccc acgacatctt cgcagggaag cctgtggacc ctctgccagg ctccacaaga
      181 ggtcaggaca gtgcagtgtg ttcacaaggc cagtttctga tcgtccgccc cgaggctgag
      241 gaccagtagg cagctcccaa gatgggtgaa aggaaagggg tcaacaagta ctatcctcca
      301 gacttcaacc ctgagaagca tggctctctc aaccgatacc acaacagcca cccgcttcgg
      361 gagcgggctc ggaagctgtc acagggcatc ctcatcatcc gattcgaaat gccatataac
      421 atctggtgcg atggctgcaa gaaccacatc ggcatgggtg ttcgttacaa tgcagaaaag
      481 aagaaggtgg gcaattacta cacaaccccg atctacaggt tccggatgaa atgccacctc
      541 tgtgtcaact acatcgagat gcagacggac cccgccaact gcgactacgt gatcgtgagt
      601 ggcgcccagc gcaaggagga gcgctgggac atggcggaca atgagcaggt gctgaccaca
      661 gagcatgaga agaagcagaa gctggagacg gacgccatgt tccggctgga gcatggcgag
      721 gccgaccgca gcacactcaa gaaggcgctg cccacactga gccacatcca ggaggcccag
      781 agcgcctgga aggacgactt cgccctcaac agcatgctgc ggagaaggtt ccgggaaaag
      841 aaaaaagcca tccaggagga ggaggagaga gaccaggcct tgcaggccaa ggcgagcctg
      901 accatcccgc tggtgcccga gacggaagat gaccgcaagc tggcggctct gctgaagttc
      961 cacaccctgg actcctacga ggacaagcag aaactcaagc ggaccgagat catcagccgc
     1021 tcctggttcc cctctgcccc cggatccgcc tccagcagca aggtcagcgg cgtcctgaag
     1081 aagctggcac agagccgcag aaccgcgctt gccacctccc ccatcaccgt cggggacctg
     1141 ggcatcgtgc ggcggaggtc tcgggacgtc ccggagagcc cccagcatgc ggccgacacc
     1201 cccaagtctg gggaaccgcg ggtaccagag gaggctgccc aggaccggcc catgtccccc
     1261 ggagactgtc ctccggaaac aactgagacc cccaagtgca gcagcccgag ggggcaggaa
     1321 gggagccgtc aggacaagcc cctgtcgcca gcaggctcct cccaggaggc agctgacacc
     1381 cccgacacgc ggcacccctg cagtctcggc tcctccctcg tggcggacta ctccgactcg
     1441 gagagtgagt gagcgatccc catcctggag actggacccg ctctagaggc ccggacacac
     1501 ccaggaggcc cctcacagac tgcagacccc cggctcgccc accagccctg ggagagctca
     1561 gatgccgcat cctccccaga ccgcgccttc ctgcaaccgt ggagttattt atttggtcct
     1621 ggtgagggtg tttgtgcctt gtgagactcc gtacattaaa gacctgtctc ttc
//
