LOCUS       NM_198537                979 bp    mRNA    linear   PRI 06-JUN-2024
DEFINITION  Homo sapiens YjeF N-terminal domain containing 3 (YJEFN3),
            transcript variant 1, mRNA.
ACCESSION   NM_198537 XM_351183
VERSION     NM_198537.4
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 979)
  AUTHORS   Luck,K., Kim,D.K., Lambourne,L., Spirohn,K., Begg,B.E., Bian,W.,
            Brignall,R., Cafarelli,T., Campos-Laborie,F.J., Charloteaux,B.,
            Choi,D., Cote,A.G., Daley,M., Deimling,S., Desbuleux,A., Dricot,A.,
            Gebbia,M., Hardy,M.F., Kishore,N., Knapp,J.J., Kovacs,I.A.,
            Lemmens,I., Mee,M.W., Mellor,J.C., Pollis,C., Pons,C.,
            Richardson,A.D., Schlabach,S., Teeking,B., Yadav,A., Babor,M.,
            Balcha,D., Basha,O., Bowman-Colin,C., Chin,S.F., Choi,S.G.,
            Colabella,C., Coppin,G., D'Amata,C., De Ridder,D., De Rouck,S.,
            Duran-Frigola,M., Ennajdaoui,H., Goebels,F., Goehring,L., Gopal,A.,
            Haddad,G., Hatchi,E., Helmy,M., Jacob,Y., Kassa,Y., Landini,S.,
            Li,R., van Lieshout,N., MacWilliams,A., Markey,D., Paulson,J.N.,
            Rangarajan,S., Rasla,J., Rayhan,A., Rolland,T., San-Miguel,A.,
            Shen,Y., Sheykhkarimli,D., Sheynkman,G.M., Simonovsky,E., Tasan,M.,
            Tejeda,A., Tropepe,V., Twizere,J.C., Wang,Y., Weatheritt,R.J.,
            Weile,J., Xia,Y., Yang,X., Yeger-Lotem,E., Zhong,Q., Aloy,P.,
            Bader,G.D., De Las Rivas,J., Gaudet,S., Hao,T., Rak,J.,
            Tavernier,J., Hill,D.E., Vidal,M., Roth,F.P. and Calderwood,M.A.
  TITLE     A reference map of the human binary protein interactome
  JOURNAL   Nature 580 (7803), 402-408 (2020)
   PUBMED   32296183
REFERENCE   2  (bases 1 to 979)
  AUTHORS   Ripke,S., O'Dushlaine,C., Chambert,K., Moran,J.L., Kahler,A.K.,
            Akterin,S., Bergen,S.E., Collins,A.L., Crowley,J.J., Fromer,M.,
            Kim,Y., Lee,S.H., Magnusson,P.K., Sanchez,N., Stahl,E.A.,
            Williams,S., Wray,N.R., Xia,K., Bettella,F., Borglum,A.D.,
            Bulik-Sullivan,B.K., Cormican,P., Craddock,N., de Leeuw,C.,
            Durmishi,N., Gill,M., Golimbet,V., Hamshere,M.L., Holmans,P.,
            Hougaard,D.M., Kendler,K.S., Lin,K., Morris,D.W., Mors,O.,
            Mortensen,P.B., Neale,B.M., O'Neill,F.A., Owen,M.J.,
            Milovancevic,M.P., Posthuma,D., Powell,J., Richards,A.L.,
            Riley,B.P., Ruderfer,D., Rujescu,D., Sigurdsson,E., Silagadze,T.,
            Smit,A.B., Stefansson,H., Steinberg,S., Suvisaari,J., Tosato,S.,
            Verhage,M., Walters,J.T., Levinson,D.F., Gejman,P.V., Kendler,K.S.,
            Laurent,C., Mowry,B.J., O'Donovan,M.C., Owen,M.J., Pulver,A.E.,
            Riley,B.P., Schwab,S.G., Wildenauer,D.B., Dudbridge,F., Holmans,P.,
            Shi,J., Albus,M., Alexander,M., Campion,D., Cohen,D., Dikeos,D.,
            Duan,J., Eichhammer,P., Godard,S., Hansen,M., Lerer,F.B.,
            Liang,K.Y., Maier,W., Mallet,J., Nertney,D.A., Nestadt,G.,
            Norton,N., O'Neill,F.A., Papadimitriou,G.N., Ribble,R.,
            Sanders,A.R., Silverman,J.M., Walsh,D., Williams,N.M., Wormley,B.,
            Arranz,M.J., Bakker,S., Bender,S., Bramon,E., Collier,D.,
            Crespo-Facorro,B., Hall,J., Iyegbe,C., Jablensky,A., Kahn,R.S.,
            Kalaydjieva,L., Lawrie,S., Lewis,C.M., Lin,K., Linszen,D.H.,
            Mata,I., McIntosh,A., Murray,R.M., Ophoff,R.A., Powell,J.,
            Rujescu,D., Van Os,J., Walshe,M., Weisbrod,M., Wiersma,D.,
            Donnelly,P., Barroso,I., Blackwell,J.M., Bramon,E., Brown,M.A.,
            Casas,J.P., Corvin,A.P., Deloukas,P., Duncanson,A., Jankowski,J.,
            Markus,H.S., Mathew,C.G., Palmer,C.N., Plomin,R., Rautanen,A.,
            Sawcer,S.J., Trembath,R.C., Viswanathan,A.C., Wood,N.W.,
            Spencer,C.C., Band,G., Bellenguez,C., Freeman,C., Hellenthal,G.,
            Giannoulatou,E., Pirinen,M., Pearson,R.D., Strange,A., Su,Z.,
            Vukcevic,D., Donnelly,P., Langford,C., Hunt,S.E., Edkins,S.,
            Gwilliam,R., Blackburn,H., Bumpstead,S.J., Dronov,S., Gillman,M.,
            Gray,E., Hammond,N., Jayakumar,A., McCann,O.T., Liddle,J.,
            Potter,S.C., Ravindrarajah,R., Ricketts,M.,
            Tashakkori-Ghanbaria,A., Waller,M.J., Weston,P., Widaa,S.,
            Whittaker,P., Barroso,I., Deloukas,P., Mathew,C.G., Blackwell,J.M.,
            Brown,M.A., Corvin,A.P., McCarthy,M.I., Spencer,C.C., Bramon,E.,
            Corvin,A.P., O'Donovan,M.C., Stefansson,K., Scolnick,E.,
            Purcell,S., McCarroll,S.A., Sklar,P., Hultman,C.M. and
            Sullivan,P.F.
  CONSRTM   Multicenter Genetic Studies of Schizophrenia Consortium; Psychosis
            Endophenotypes International Consortium; Wellcome Trust Case
            Control Consortium 2
  TITLE     Genome-wide association analysis identifies 13 new risk loci for
            schizophrenia
  JOURNAL   Nat Genet 45 (10), 1150-1159 (2013)
   PUBMED   23974872
REFERENCE   3  (bases 1 to 979)
  AUTHORS   Rudolph,C., Sigruener,A., Hartmann,A., Orso,E., Bals-Pratsch,M.,
            Gronwald,W., Seifert,B., Kalbitzer,H.R., Verdorfer,I.,
            Luetjens,C.M., Ortmann,O., Bornstein,S.R. and Schmitz,G.
  TITLE     ApoA-I-binding protein (AI-BP) and its homologues hYjeF_N2 and
            hYjeF_N3 comprise the YjeF_N domain protein family in humans with a
            role in spermiogenesis and oogenesis
  JOURNAL   Horm Metab Res 39 (5), 322-335 (2007)
   PUBMED   17533573
REFERENCE   4  (bases 1 to 979)
  AUTHORS   Grimwood,J., Gordon,L.A., Olsen,A., Terry,A., Schmutz,J.,
            Lamerdin,J., Hellsten,U., Goodstein,D., Couronne,O.,
            Tran-Gyamfi,M., Aerts,A., Altherr,M., Ashworth,L., Bajorek,E.,
            Black,S., Branscomb,E., Caenepeel,S., Carrano,A., Caoile,C.,
            Chan,Y.M., Christensen,M., Cleland,C.A., Copeland,A., Dalin,E.,
            Dehal,P., Denys,M., Detter,J.C., Escobar,J., Flowers,D.,
            Fotopulos,D., Garcia,C., Georgescu,A.M., Glavina,T., Gomez,M.,
            Gonzales,E., Groza,M., Hammon,N., Hawkins,T., Haydu,L., Ho,I.,
            Huang,W., Israni,S., Jett,J., Kadner,K., Kimball,H., Kobayashi,A.,
            Larionov,V., Leem,S.H., Lopez,F., Lou,Y., Lowry,S., Malfatti,S.,
            Martinez,D., McCready,P., Medina,C., Morgan,J., Nelson,K.,
            Nolan,M., Ovcharenko,I., Pitluck,S., Pollard,M., Popkie,A.P.,
            Predki,P., Quan,G., Ramirez,L., Rash,S., Retterer,J., Rodriguez,A.,
            Rogers,S., Salamov,A., Salazar,A., She,X., Smith,D., Slezak,T.,
            Solovyev,V., Thayer,N., Tice,H., Tsai,M., Ustaszewska,A., Vo,N.,
            Wagner,M., Wheeler,J., Wu,K., Xie,G., Yang,J., Dubchak,I.,
            Furey,T.S., DeJong,P., Dickson,M., Gordon,D., Eichler,E.E.,
            Pennacchio,L.A., Richardson,P., Stubbs,L., Rokhsar,D.S.,
            Myers,R.M., Rubin,E.M. and Lucas,S.M.
  TITLE     The DNA sequence and biology of human chromosome 19
  JOURNAL   Nature 428 (6982), 529-535 (2004)
   PUBMED   15057824
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BI520231.1, AK126916.1 and BC020948.1.
            
            On Nov 22, 2018 this sequence version replaced NM_198537.3.
            
            Transcript Variant: This variant (1) represents the longer
            transcript and it encodes the longer protein (isoform 1).
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC020948.1, ERR279830.2317.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA1968968, SAMEA2145743
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            gene product(s) localized to mito. :: inferred from homology
            MANE Ensembl match                 :: ENST00000514277.6/
                                                  ENSP00000426964.1
            RefSeq Select criteria             :: based on conservation,
                                                  expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-4                 BI520231.1         51-54
            5-81                AK126916.1         18-94
            82-619              BC020948.1         82-619
            620-976             AK126916.1         2409-2765
            977-979             BC020948.1         978-980
FEATURES             Location/Qualifiers
     source          1..979
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="19"
                     /map="19p13.11"
     gene            1..979
                     /gene="YJEFN3"
                     /note="YjeF N-terminal domain containing 3"
                     /db_xref="GeneID:374887"
                     /db_xref="HGNC:HGNC:24785"
                     /db_xref="MIM:618607"
     exon            1..81
                     /gene="YJEFN3"
                     /inference="alignment:Splign:2.1.0"
     CDS             23..922
                     /gene="YJEFN3"
                     /note="isoform 1 is encoded by transcript variant 1;
                     hYjeF_N3-19p13.11; yjeF N-terminal domain-containing
                     protein 3; apolipoprotein A1 binding protein; yjeF_N3;
                     apoA-I-binding protein 2"
                     /codon_start=1
                     /product="yjeF N-terminal domain-containing protein 3
                     isoform 1"
                     /protein_id="NP_940939.2"
                     /db_xref="CCDS:CCDS42530.1"
                     /db_xref="GeneID:374887"
                     /db_xref="HGNC:HGNC:24785"
                     /db_xref="MIM:618607"
                     /translation="MSSAAGPDPSEAPEERHFLRALELQPPLADMGRAELSSNATTSL
                     VQRRKQAWGRQSWLEQIWNAGPVCQSTAEAAALERELLEDYRFGRQQLVELCGHASAV
                     AVTKAFPLPALSRKQRTVLVVCGPEQNGAVGLVCARHLRVFEYEPTIFYPTRSLDLLH
                     RDLTTQCEKMDIPFLSYLPTEVQLINEAYGLVVDAVLGPGVEPGEVGGPCTRALATLK
                     LLSIPLVSLDIPSGWDAETGSDSEDGLRPDVLVSLAAPKRCAGRFSGRHHFVAGRFVP
                     DDVRRKFALRLPGYTGTDCVAAL"
     exon            82..231
                     /gene="YJEFN3"
                     /inference="alignment:Splign:2.1.0"
     exon            232..340
                     /gene="YJEFN3"
                     /inference="alignment:Splign:2.1.0"
     exon            341..451
                     /gene="YJEFN3"
                     /inference="alignment:Splign:2.1.0"
     exon            452..565
                     /gene="YJEFN3"
                     /inference="alignment:Splign:2.1.0"
     exon            566..716
                     /gene="YJEFN3"
                     /inference="alignment:Splign:2.1.0"
     exon            717..979
                     /gene="YJEFN3"
                     /inference="alignment:Splign:2.1.0"
     regulatory      958..963
                     /regulatory_class="polyA_signal_sequence"
                     /gene="YJEFN3"
                     /note="hexamer: AATAAA"
     polyA_site      979
                     /gene="YJEFN3"
                     /note="major polyA site"
ORIGIN      
        1 ggcgcccggg ctcacctcgg ccatgagcag cgcagccggc ccagacccgt cggaggcgcc
       61 cgaagagcgg catttcctca gggccttgga gctgcagccc ccacttgccg acatgggaag
      121 agcggagctt agctcaaatg ctaccacctc ccttgtccag aggaggaaac aggcctgggg
      181 aaggcagtca tggctagagc agatttggaa cgcagggcct gtttgccaga gcaccgcgga
      241 ggcagccgcc ctggagcggg agctgctgga ggattatcgc tttgggcggc agcagctcgt
      301 ggagctgtgc ggtcatgcta gtgccgtggc tgtgaccaag gcgttcccgt tgcccgctct
      361 ctcccggaag cagaggacgg tgctggtcgt gtgtggcccg gagcagaacg gggcagtggg
      421 gctggtctgt gcccggcacc tgcgggtgtt tgagtatgaa cccaccatct tctaccccac
      481 acgctcgctg gacctgctgc atcgggacct gaccacccag tgcgagaaga tggacatccc
      541 cttcctgagc tacctgccca ctgaggtgca gctcattaac gaagcctatg ggctggtggt
      601 ggatgccgta ctgggccccg gcgtggagcc gggcgaggtc gggggcccct gcacccgcgc
      661 gctggccacg ctcaagctgc tgtccatccc cctcgtgagc ctggacatcc cctcaggctg
      721 ggacgcagag accggcagcg attcggagga cgggctgcgg cctgacgtgc tggtgtctct
      781 cgcggcgccc aagcgctgcg ctggccgctt ctccgggcgc caccacttcg tggccggcag
      841 gttcgtgccc gatgacgtgc gccgcaagtt cgctctgcgc ctgccgggat acacgggcac
      901 cgactgcgtc gcggcactgt gaccgccacc cgcggccaca ccgcagggac cctcgccaat
      961 aaacagccct cccaccacc
//
