LOCUS       NM_032312              11955 bp    mRNA    linear   PRI 04-APR-2024
DEFINITION  Homo sapiens Yip1 domain family member 4 (YIPF4), mRNA.
ACCESSION   NM_032312
VERSION     NM_032312.4
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 11955)
  AUTHORS   Luck,K., Kim,D.K., Lambourne,L., Spirohn,K., Begg,B.E., Bian,W.,
            Brignall,R., Cafarelli,T., Campos-Laborie,F.J., Charloteaux,B.,
            Choi,D., Cote,A.G., Daley,M., Deimling,S., Desbuleux,A., Dricot,A.,
            Gebbia,M., Hardy,M.F., Kishore,N., Knapp,J.J., Kovacs,I.A.,
            Lemmens,I., Mee,M.W., Mellor,J.C., Pollis,C., Pons,C.,
            Richardson,A.D., Schlabach,S., Teeking,B., Yadav,A., Babor,M.,
            Balcha,D., Basha,O., Bowman-Colin,C., Chin,S.F., Choi,S.G.,
            Colabella,C., Coppin,G., D'Amata,C., De Ridder,D., De Rouck,S.,
            Duran-Frigola,M., Ennajdaoui,H., Goebels,F., Goehring,L., Gopal,A.,
            Haddad,G., Hatchi,E., Helmy,M., Jacob,Y., Kassa,Y., Landini,S.,
            Li,R., van Lieshout,N., MacWilliams,A., Markey,D., Paulson,J.N.,
            Rangarajan,S., Rasla,J., Rayhan,A., Rolland,T., San-Miguel,A.,
            Shen,Y., Sheykhkarimli,D., Sheynkman,G.M., Simonovsky,E., Tasan,M.,
            Tejeda,A., Tropepe,V., Twizere,J.C., Wang,Y., Weatheritt,R.J.,
            Weile,J., Xia,Y., Yang,X., Yeger-Lotem,E., Zhong,Q., Aloy,P.,
            Bader,G.D., De Las Rivas,J., Gaudet,S., Hao,T., Rak,J.,
            Tavernier,J., Hill,D.E., Vidal,M., Roth,F.P. and Calderwood,M.A.
  TITLE     A reference map of the human binary protein interactome
  JOURNAL   Nature 580 (7803), 402-408 (2020)
   PUBMED   32296183
REFERENCE   2  (bases 1 to 11955)
  AUTHORS   Huttlin,E.L., Bruckner,R.J., Paulo,J.A., Cannon,J.R., Ting,L.,
            Baltier,K., Colby,G., Gebreab,F., Gygi,M.P., Parzen,H., Szpyt,J.,
            Tam,S., Zarraga,G., Pontano-Vaites,L., Swarup,S., White,A.E.,
            Schweppe,D.K., Rad,R., Erickson,B.K., Obar,R.A., Guruharsha,K.G.,
            Li,K., Artavanis-Tsakonas,S., Gygi,S.P. and Harper,J.W.
  TITLE     Architecture of the human interactome defines protein communities
            and disease networks
  JOURNAL   Nature 545 (7655), 505-509 (2017)
   PUBMED   28514442
REFERENCE   3  (bases 1 to 11955)
  AUTHORS   Kranjc,T., Dempsey,E., Cagney,G., Nakamura,N., Shields,D.C. and
            Simpson,J.C.
  TITLE     Functional characterisation of the YIPF protein family in mammalian
            cells
  JOURNAL   Histochem Cell Biol 147 (4), 439-451 (2017)
   PUBMED   27999994
  REMARK    GeneRIF: The significance of YIPF4 protein for the maintenance of
            the morphology of the Golgi was tested by RNA interference,
            revealing a number of specific morphological changes to this
            organelle on their depletion.
REFERENCE   4  (bases 1 to 11955)
  AUTHORS   Muller,M., Wasson,C.W., Bhatia,R., Boxall,S., Millan,D., Goh,G.Y.,
            Haas,J., Stonehouse,N.J. and Macdonald,A.
  TITLE     YIP1 family member 4 (YIPF4) is a novel cellular binding partner of
            the papillomavirus E5 proteins
  JOURNAL   Sci Rep 5, 12523 (2015)
   PUBMED   26235900
  REMARK    GeneRIF: YIPF4 is a binding partner of the papillomavirus E5
            proteins.
            Publication Status: Online-Only
REFERENCE   5  (bases 1 to 11955)
  AUTHORS   Tanimoto,K., Suzuki,K., Jokitalo,E., Sakai,N., Sakaguchi,T.,
            Tamura,D., Fujii,G., Aoki,K., Takada,S., Ishida,R., Tanabe,M.,
            Itoh,H., Yoneda,Y., Sohda,M., Misumi,Y. and Nakamura,N.
  TITLE     Characterization of YIPF3 and YIPF4, cis-Golgi Localizing Yip
            domain family proteins
  JOURNAL   Cell Struct Funct 36 (2), 171-185 (2011)
   PUBMED   21757827
  REMARK    GeneRIF: YIPF4 was detected as a single mobility form consistent
            with its predicted molecular weight, three different mobility forms
            of YIPF3 were detected by western blotting.
REFERENCE   6  (bases 1 to 11955)
  AUTHORS   Ohira,M., Morohashi,A., Nakamura,Y., Isogai,E., Furuya,K.,
            Hamano,S., Machida,T., Aoyama,M., Fukumura,M., Miyazaki,K.,
            Suzuki,Y., Sugano,S., Hirato,J. and Nakagawara,A.
  TITLE     Neuroblastoma oligo-capping cDNA project: toward the understanding
            of the genesis and biology of neuroblastoma
  JOURNAL   Cancer Lett 197 (1-2), 63-68 (2003)
   PUBMED   12880961
  REMARK    Review article
REFERENCE   7  (bases 1 to 11955)
  AUTHORS   Simpson,J.C., Wellenreuther,R., Poustka,A., Pepperkok,R. and
            Wiemann,S.
  TITLE     Systematic subcellular localization of novel proteins identified by
            large-scale cDNA sequencing
  JOURNAL   EMBO Rep 1 (3), 287-292 (2000)
   PUBMED   11256614
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BP207600.1, BC004875.2, AL121653.2, BU608699.1 and AL133245.4.
            
            On Nov 22, 2018 this sequence version replaced NM_032312.3.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR1660807.168893.1,
                                           SRR1660807.155128.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA1965299, SAMEA1966682
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000238831.9/ ENSP00000238831.3
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-58                BP207600.1         19-76
            59-1502             BC004875.2         1-1444
            1503-1926           AL121653.2         129850-130273
            1927-1950           BU608699.1         18-41               c
            1951-10562          AL121653.2         130298-138909
            10563-11955         AL133245.4         26047-27439
FEATURES             Location/Qualifiers
     source          1..11955
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="2"
                     /map="2p22.3"
     gene            1..11955
                     /gene="YIPF4"
                     /gene_synonym="FinGER4; Nbla11189; YIPFalpha2"
                     /note="Yip1 domain family member 4"
                     /db_xref="GeneID:84272"
                     /db_xref="HGNC:HGNC:28145"
                     /db_xref="MIM:617534"
     exon            1..331
                     /gene="YIPF4"
                     /gene_synonym="FinGER4; Nbla11189; YIPFalpha2"
                     /inference="alignment:Splign:2.1.0"
     CDS             253..987
                     /gene="YIPF4"
                     /gene_synonym="FinGER4; Nbla11189; YIPFalpha2"
                     /note="putative protein product of Nbla11189; YIP1 family
                     member 4"
                     /codon_start=1
                     /product="protein YIPF4"
                     /protein_id="NP_115688.1"
                     /db_xref="CCDS:CCDS1781.1"
                     /db_xref="GeneID:84272"
                     /db_xref="HGNC:HGNC:28145"
                     /db_xref="MIM:617534"
                     /translation="MQPPGPPPAYAPTNGDFTFVSSADAEDLSGSIASPDVKLNLGGD
                     FIKESTATTFLRQRGYGWLLEVEDDDPEDNKPLLEELDIDLKDIYYKIRCVLMPMPSL
                     GFNRQVVRDNPDFWGPLAVVLFFSMISLYGQFRVVSWIITIWIFGSLTIFLLARVLGG
                     EVAYGQVLGVIGYSLLPLIVIAPVLLVVGSFEVVSTLIKLFGVFWAAYSAASLLVGEE
                     FKTKKPLLIYPIFLLYIYFLSLYTGV"
     exon            332..485
                     /gene="YIPF4"
                     /gene_synonym="FinGER4; Nbla11189; YIPFalpha2"
                     /inference="alignment:Splign:2.1.0"
     exon            486..657
                     /gene="YIPF4"
                     /gene_synonym="FinGER4; Nbla11189; YIPFalpha2"
                     /inference="alignment:Splign:2.1.0"
     exon            658..735
                     /gene="YIPF4"
                     /gene_synonym="FinGER4; Nbla11189; YIPFalpha2"
                     /inference="alignment:Splign:2.1.0"
     exon            736..849
                     /gene="YIPF4"
                     /gene_synonym="FinGER4; Nbla11189; YIPFalpha2"
                     /inference="alignment:Splign:2.1.0"
     exon            850..11955
                     /gene="YIPF4"
                     /gene_synonym="FinGER4; Nbla11189; YIPFalpha2"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1227..1232
                     /regulatory_class="polyA_signal_sequence"
                     /gene="YIPF4"
                     /gene_synonym="FinGER4; Nbla11189; YIPFalpha2"
                     /note="hexamer: AATACA"
     polyA_site      1250
                     /gene="YIPF4"
                     /gene_synonym="FinGER4; Nbla11189; YIPFalpha2"
                     /note="major polyA site"
     regulatory      1912..1917
                     /regulatory_class="polyA_signal_sequence"
                     /gene="YIPF4"
                     /gene_synonym="FinGER4; Nbla11189; YIPFalpha2"
                     /note="hexamer: AATAAA"
     polyA_site      1947
                     /gene="YIPF4"
                     /gene_synonym="FinGER4; Nbla11189; YIPFalpha2"
                     /note="major polyA site"
     regulatory      7081..7086
                     /regulatory_class="polyA_signal_sequence"
                     /gene="YIPF4"
                     /gene_synonym="FinGER4; Nbla11189; YIPFalpha2"
                     /note="hexamer: AATAAA"
     polyA_site      7105
                     /gene="YIPF4"
                     /gene_synonym="FinGER4; Nbla11189; YIPFalpha2"
                     /note="major polyA site"
     regulatory      11935..11940
                     /regulatory_class="polyA_signal_sequence"
                     /gene="YIPF4"
                     /gene_synonym="FinGER4; Nbla11189; YIPFalpha2"
                     /note="hexamer: AATAAA"
     polyA_site      11955
                     /gene="YIPF4"
                     /gene_synonym="FinGER4; Nbla11189; YIPFalpha2"
ORIGIN      
        1 gtcactgtta tggtcctgtc agggtgccgg cgtcgtggtg cttgggtggt cgccaccaag
       61 aagactttgg tggggtagtc tcggggcagc tcagcggccc gctgtgcccg tttctggcct
      121 cgctcgcagc ttgcacgtcg agactcgtag gccgcaccgt agggcgagcg tgcgggtcgc
      181 cgccgcggcc gcctcggggt ctgggcccag ccgcagcctc ttctaccgcg gccggttggg
      241 agtcgccgcg agatgcagcc tccgggcccg cccccggcct atgcccccac taacggggac
      301 ttcacctttg tctcctcagc agacgcggaa gatctcagtg gttcaatagc atccccagat
      361 gtcaaattaa atcttggtgg agattttatc aaagaatcta cagctactac atttctgaga
      421 caaagaggtt atggctggct tctggaagtt gaagatgatg atcctgaaga taacaagcca
      481 ctcttggaag aattggacat tgatctaaag gatatttact acaaaatccg atgtgttttg
      541 atgccaatgc catcacttgg ttttaataga caagtggtga gagacaatcc tgacttttgg
      601 ggtcctctgg ctgttgttct tttcttttcc atgatatcat tatatggaca gtttagggtg
      661 gtctcatgga ttataaccat ttggatattt ggttcactaa caattttctt actggccaga
      721 gttcttggtg gagaagttgc atatggccaa gtccttggag ttataggata ttcattactt
      781 cctctcattg taatagcccc tgtacttttg gtggttggat catttgaagt ggtgtctaca
      841 cttataaaac tgtttggtgt gttttgggct gcctacagtg ctgcttcatt gttagtgggt
      901 gaagaattca agaccaaaaa gcctcttctg atttatccaa tctttttatt atacatttat
      961 tttttgtcgt tatatactgg tgtgtgatcc aagttataca tgaatagaaa aagatggtgt
     1021 taaatttgtg tgtaggctgg gaattcttgc tgaaggaatt ggagaaaacc tgttgctgca
     1081 aaattttaca tgttccagat ggaaagggaa gtctaagcgc tttttaaaac aatttttttt
     1141 tgtatttaat taagcaattg cagttatctg ggatttttgg gtcagaattt taaattctgt
     1201 ttgattctcc atattccagt gaataaaata caaaagcatt gtgtttttaa gattgtgtcg
     1261 atattcacct aaaaacttgt gccaaaagca cctggattgg taattatatt tcacttaaag
     1321 ggtaaatttg acaatatctt gataatcaaa agtgcaattt ttttcttcaa aatgttttct
     1381 ccagcatcac agatcctgca gatatatatt tatatttata catatatatt tatgaaataa
     1441 ttcttactca caaaatatat ttctgataaa cattaagata ttaaatctga tgcacaaact
     1501 ttttaatttg gccattaatc ttttttattt aaaaatttaa atttgttttt aaaattgtat
     1561 atagttttta aaatctcaca catgcttcga tacttccttg ttaagaattc ttaataacta
     1621 ctaaaactga tttttaatag ttgctgatat atatttggtt tgtttgggta tacttttcaa
     1681 aaccattttt gaatgtccaa acatctgatt taaagtttct gtttatcttt ctgaccaaag
     1741 gagcaagagg tataatggat atggcattca ttaaaatctt tactatgtac aaaaacagta
     1801 atatttacag catcagtaaa tatttttaag tggtacttct aaatcataaa agttggggaa
     1861 agagaccttt aaaatcttgt ggtgttgaac aatgttatat gaagtagaaa aaataaaata
     1921 cttcccagtt gtgtgttttg ttttacagca ccatgtcctg tattacttga tattttaaca
     1981 agtatcaggt actctctaac aaatgtacag tttttgctaa gggaaatatt aagaaatttt
     2041 tatcagtgaa atatttgttg caaataattt cataggtttt tagatacacc tgtagttaat
     2101 attactttgt aaagtaggta aatcatttta tttatgtcca taaaatatca aatgtctgtt
     2161 aactattagc aaattattgt attatccttt ctggtctcac ctggaagagt ttcctgctgt
     2221 cctcagtatg ataacatggc gacctcttgg tatgtatttc tttagcaaac ttacccatca
     2281 ggaaatatcc agcacctctg aagcaaacct acaaatgagt gtgttatcaa gcccagccgt
     2341 cttcctttcc cctaatccca aaaggaaaga aagaaaaact tattttaagc tgcagaaaaa
     2401 gtgtggagca cttttgagct agaataatgt agaaaattac atgtactgat ttttttaaaa
     2461 acaggtgaga agcaccagag ggacaggact tctagaagtt agaataatat gaagtaatca
     2521 ggaaatatct atgcctacag aagcagcaac cgtaagataa acatttgtta cacttaagaa
     2581 attgctgagg ttaatacttt gttataatgg attataatat ttgacattca tagtgttgac
     2641 cctggaatct ttcacagaaa gcttgggggt caggaccagg aggtagaatt ttacaaggca
     2701 ataaatgaag gtattttaag atcacctcta ttaaaaaatg gtttaatttt taaaaactat
     2761 cattgcttta aggtatgaat tttaaaaatc acttatatgg atcatgttta ctcctaatga
     2821 tataagataa aatgaggtat ttttgttcca aaaagtattt taaaatagca tttaatcttg
     2881 ggaactatct tacttagggt ttctataaat acaaattaca atgtttcgaa ctcaaccagt
     2941 atcattttcg tgtgctaatg agcaaagtag ttagaacaga ttgtcagttt aaaaacagga
     3001 tttgtaggcc aggcacagtg gctcacgcct gtaatcccag cactttggga ggccaaagtg
     3061 gatgagcagc ttgagtcagg agtttgagac cagcctggcc aacatggcga aaccccgtct
     3121 ctactaaaaa tacaaaaatt agccgggcgt ggtggcaggc gcctgtataa tcccagctac
     3181 tcaggaggct gaggcaggga gaatcgcttg aacccttgga ggtggaggtt gcagtgagcc
     3241 aagattgtgc cattgcactc cagcctgggt aacagagcaa gactctctca aaaaaaaaaa
     3301 aaaaaaaaaa aaaaaccatg atttgtagat gtgtgcaaga cacagtactg ctatggctaa
     3361 taatggtaag atgaccctaa taatgtcctc tccttgaatt tttatataat aatattttct
     3421 gagtcataac taatttttta aataatgatt tccaatctaa ttattaatta gaattttgtt
     3481 gttgttgttt gagacagagt cactctgtca cccaagctgg agtgcaatgg cacgatctcg
     3541 gctcactgca agctctgcct cccgggtttg caccattctt ctgcctcagc ctcacgagta
     3601 gctgggacta caggcgccca ccaccatgcc tggctaattt tttgtatttt tagtagagat
     3661 ggggtttcac cgtgttaacc aggatggtct cgatctcctg acctcgtgat ccgcccgcct
     3721 cagcctccca aagtgccggg attacaggtg tcagccaccg caccaggcca gttcattaga
     3781 atttttaaaa caggctgggc atggtggctt acgcctgtaa tcccagcagt ttgggaggcc
     3841 gaggcaggtg gatcacctga ggttgggagt ttgagaccag cctgaccaat gtggagaaac
     3901 cccatctcta ctaagaatac aaaattagcc aggcatggtg gtgcatacct gtaatctcag
     3961 ctactgggga agctgagaca ggagaattgc ttgaacccag gaggcagagg ttgcggtgag
     4021 ctgagatcgc gccattgcac tccagcctgg gcaacaggag tgaaactcca tctcaagaaa
     4081 aacacaaaat acaaaacaaa acaaaacaaa aaaacagaac tgggccgggc gcggtggctc
     4141 acgcctgtaa tcccagcact ttgggaggcc gaggcgggtg gatcacgaga tcaggagatc
     4201 aagaccatgg tgaaaccccg tctctactaa aaatacaata aattagccgg gcatggtggc
     4261 gggcgcctgt agtcccagct acttgggagg ctgaggcagg agaatcgctt gaacccggga
     4321 ggcagaggtt gcagtgagcc aagatcgtgc cactgcactc cagcctaggt gacagagtga
     4381 gactccgtct caaaaaaaaa aaaaaaaaaa atcaaaatct atataattaa gcattgtttt
     4441 ttaaaaagta gtttaggaag atttgtaaag cttatgaacc attgtaaaac cttatttcta
     4501 aggtctgtaa gacagtttta tatgtaataa tgtgtccatt tccaggaatt ccccaaatac
     4561 tcatacagcc attgagcacc ccaatccaaa attcagaatg cttcagataa gaacattttt
     4621 gagtgccgat gtgacacttt aaaggaaatg ttcattggag cattttgcat ttcagatttt
     4681 tggattagga aaactcaacc actgtatttc tgcacatatt ccaaaatctg aaaaagtctg
     4741 aaacctgaga aactctggtc ccaagcattt tggaaagggt atactcaatc tgtattaaca
     4801 tagacttcta aattagtgaa aatttgcatt gaattaaaat gtgaagtaaa tatttttgtt
     4861 taaatattgt ttaaaattta gtcatttaaa aattttgtga tgtaacaaaa tgttgaatga
     4921 aataatgctt ctacaactta aaattatttt tcatagtgaa caaaactagt tgaatacttc
     4981 taaatattca tttttgttag tgcacatttt atccagtttt aggctttagg gaattgtgac
     5041 cctttttttt tttttttttt tttttttgga gacggagtct tgctctctcg cccaggctgg
     5101 agtgtgtggc gcaatctcag ctcactgcaa cctctgattc ctgggttcaa gcaattctca
     5161 tgtctcagcc tccctaatag ctaggattac cggtgcccgc caccacgccc agctaatttt
     5221 ttaaattttt aatggagaca gggtttcacc atgttggcca ggctggtctt aaactcctga
     5281 cctcaggtga tccacccacc ttggcctccc aaagtgctgg gattacaggc ttaagccacc
     5341 gtgcccggca cttttgtttt taaaataata tcttactttc atatgattct ttcagactgt
     5401 ggtatggcat tctgaagcaa gtcttaacag agctaaaaat cacccttacc caattctctg
     5461 cactgacata tgtacacaaa gtaatatttt attattctcc ttcataaatg gtttctttaa
     5521 ttgaaccttt gagccttata ctatttttaa atttcccttt aaaaattgaa ttacagccag
     5581 gcatggtggc tcatgcctgt aatcccagaa ctttgggagg ccatggcagg aggattgctt
     5641 gaacccagga gttgtagacc agcctgggca agatagcgag atcctgcctc tgaaaaaatc
     5701 ataataatac tttaatttag aaaataccct gaattagaag tgcttcattc ctcatttgtg
     5761 tacagctgtt cctctatata cgaaggggat tggtaccaga accactgcat accaaattcc
     5821 acccatactc aagtctcaca gtcttccctg cagaatccaa gtatacaaaa agtaggccta
     5881 tcatttatat gggttttgca tcctgacagt actgtatttt caatcctagt ttgtttggga
     5941 aaaaaaaatt gtttgtatgc ctgggtacag tatcatacct gtaatcccag cactttggaa
     6001 ggctgaggcg ggaggactgt tttgtggcca ggagttcaaa atcagcctgg tcgacgtagt
     6061 gagaccccat ctctacaaaa gaaaaattag ctgggcatgt ggcacctgcc tgtggtccca
     6121 gctactcagg aggctgtgag gcaggagaat tgcttgagcc tgggaggttg aggctgcagt
     6181 gagccgcgat cacaccactg catgccagcc tgggcgacag agtgagaccc tgtctcagaa
     6241 aagaaaaaaa aagtaaaaat tgcatgtaag ttgacccgca ctattcaaat ttgtggtgtt
     6301 caaggttcaa ctgtaatttc ctagcagcat tttgtgtgtt tgagaatctc ttgacactct
     6361 tcaagtaaat ccctaaatta caactttgac atcaaaaaag ctagacattc ctacattttt
     6421 gcactacaat acataaaaac tcccatgctg atcggttgtg ggatcgtgcc tgtgaataac
     6481 cactgcactc cagcctgggc aacatagtaa gtaagacctt gtctcttaaa aaaaatacat
     6541 tctgaagaaa gttctactta tgaatacatt ttatttataa caaactggtg aaaattttag
     6601 accaaaccat gtctttctgg gttgtagtga ttaaaaaatg gttaagagaa tgttccctat
     6661 acaaggcata tgttattaaa catgaaattt aggattagtt ttctctttga aaattctttt
     6721 gatatgctga ggttacagtt tggaggttac attagagaaa gaatataggg aagatggcag
     6781 tggtaaaaca tttccctgct ttacattttt atattggcag tatcttggtt tcaacttttc
     6841 tattttcagc aagatatttg caagttttta ctttgaagat gtttggttta tagtagtcca
     6901 tgctatacta atgctgttgc tgagataatt aagttagata ctaatatgaa aaagaatatt
     6961 tgtgtaaaat attttgaagt tgtaattagt gtatatacaa gttgttaata cttacgaaaa
     7021 aaggaagcat tcccacctgt aataattttg ttaacactag actatcagta aattatcaag
     7081 aataaaaacc ttggtttttc tgtaatattt gccactgagc aatttttatt aaaaaccaaa
     7141 cagaagtatt tacacaagaa caagtgaaat tacacaaaat gataatgggg agaaatttct
     7201 catctggtga taaagggaaa aagataatgt aaaagcagat tgctgctatt tgcataataa
     7261 gcacttgttg aagaataaat gattaagttc aatatttttg ctctatttta tacctactca
     7321 ctttggtgga attagttctc catgtaaagt atctttttaa tagtaagcac catttaataa
     7381 tgaaacaact catatgtttt gtaatcctta tggagaatta cttcatgtga taattatagt
     7441 ctcttcatgg aaaacagtaa aaatactcac gtttatgatg atgggcctag gtactaaatt
     7501 cctcattcaa tcttttttta ccaaatggta cttaataaaa tcttttacct tataaaaatc
     7561 tattttcggc caggcgcggt ggctcacgcc tgtaatccca gcactttggg aggccgaggt
     7621 gggcggacca cgaggtcagg agatcgagac catcctggct aacacggtga aaccctgact
     7681 ctactaaaaa taccaaaaat tagccgggcg tggcagcggg cgcctgtagt ctcagctact
     7741 cgggaggctg aggcaggaga atggcgtgta cccgggaggc ggaggttgca gtgagccgag
     7801 atcgcgccac tgcactccag cctgggcgac agagcgagaa tccgtctcaa aaaaaaaaaa
     7861 aaaaaaaaaa aaaaaaaaaa ttattttcaa aggattgtgc tagtggtggc ctgaataata
     7921 aaacattgag aagaaacagc ctttgaattt ggcaccctga atgtgaaggg acaatagata
     7981 ttaatcacat atttattaac cccttcctgt atgaacctag tactgtgctg agtgtaggga
     8041 tacagtgata atgcaaaaaa gacccccaat aggccgggcg cggtggctca cgcctgcaat
     8101 cccagcactt tgggagaccg aggcgggtgg atcacgaggt caggggatcg agaccatcct
     8161 ggctaacacg gtgaaacccc gtctctacta aaaatacaaa atttagccgg gcgtggtagc
     8221 aggcgcctgt agtcccagct gcttgggagg ctgcggcagg agaatggtgt gaacccggga
     8281 ggcggagctt gcagtaagca gagatcgcgc cactgcactc ccgcctgggt gacagagcga
     8341 gactctgtct caaaaaaaaa gaccgccccc cccaatatac acacaccctg actttaatga
     8401 gcttattttg ctggggactc agccaattaa tttcacaaat tgtaaaacta tttcaagaaa
     8461 tgagaaaaag aggcctgtgg tggtaagcaa gtatataaaa gaagccttcc ttgaagcaac
     8521 gatgcttaag ctgaaatctt agggaaaaat aaaagttaac taggcaaaga aggtagggaa
     8581 gactctttca gatagaatcg cagtttgtga gtttgcttgg ggaaaaaaat ttaaaaatat
     8641 aaaaagaaaa ccagtttgaa gtttagtggt taatgaaatt gaacaggtat gtcagcacca
     8701 tacctgacat tctaggccat tctttctttg tcagagcttt tttgttgaga tggagtctcg
     8761 ctgtctcgct gaggctggag tgcagtggtg caatctcggc tcactgcaac ctctgcctcc
     8821 caggttcaag tgattctcct gcctcagcct cccaagtagc tgggattaca ggtgcccatc
     8881 accacacccg gctaattttt ttgtttttag taaagacggt ttctccatgt aggccaagcg
     8941 ggtcttgaac tcccaacctc cggtgatctg cccacctcaa cctcccaaag tgctgggatt
     9001 acaggcgtga gacactgtgc ccagcctgtc agagcttttg agtagaaata cggtatcaga
     9061 aatgtgcttt attttatttt attagacaaa gtcttgctct gttgccaggc tggagtgcag
     9121 tggcgcgatc ttggctcact gcaacctctg ccttctgggt tcaagcgatt ctcctgcctc
     9181 agcctcccga gtagctggga ttacaggcac ccactgccac actcggctaa tttttgtatt
     9241 tttagtagag acgggatttc accatgttgg tctcgaactg ctaacctcag gtgatctgcc
     9301 cgccttggcc tcccaaagtg ctgggattat aggcatgaac cactgcgccc agccagaaac
     9361 gtgcttttaa tactaaaggc caagatatgc aattatactc ttgacatata ttcaaccgaa
     9421 atgcatgtac atgtaccata agagacatat gtacaagaat gtgcacagtt aacattattc
     9481 aaatagccaa aaacgggaac atgtccatca acacagaata gacaagttgg tataattaca
     9541 caatggaatc ttatgcagca atgaaaataa atgaactaaa gccgcataca aaaacatgaa
     9601 gaatttcaca agtattatgt tgagtgaaaa agacaaagaa tttgtactgt attacttcat
     9661 ttatatgaag ttcaaacaca ggcaaaatta agctatagtg tttagggatg catactgaaa
     9721 tgcagtcttt taaaacagct ttagaattcc ttggccaggt gcggtggctt acgcctgtaa
     9781 tcccagctct ttgggaggca gaggctggca gatcacctga ggttgggagt ttgagaccag
     9841 cctgaccaac atggagaaac cccatctcta ctaaaaatac aaaattagct gggcgtggtg
     9901 tcgcgtgcct gtaatcccag ctactctgga ggctgagaca ggagaatcgc ttgaacctgg
     9961 gaggtggaga gtgtggtgag ctgagatgtc accattgcac tccagcctgg gcaagaagag
    10021 caaaacttcg tctcaaaaaa aaataaaaaa ataaggctcc aagcgctgtt gtgagggtta
    10081 aatgaactag ataattaatg taataaacag aatagttttg gcattcaaca aacattggct
    10141 gttattatat tagctattaa aaatttaagt catttaggtc aatgaaacag gagggtttcc
    10201 agaattatac ccaattaatt atacatggga aggtgatgaa ggtagcatgt caaattggta
    10261 taaaaagatg gaatattaaa taagtgggga tactgtatca gataggaaca tatttggttg
    10321 caagaaacaa aaattcctgt gattactagc ttcactgtga gtttattttt tcacgtaata
    10381 aatccaaggt tacataatcc ataactgata tggcagttta acagtgttat taagaactca
    10441 aggtccattt attgctctat tctgccatct ttggtgagtg gctttcatcc tcattgtctc
    10501 agaaaagtta tttcacctct aagtattaca tctacatttc aagcaggaag aagatgaagc
    10561 ttaagagacc aaatggagca tgtcagtcaa aggtgtcctt atttaaaatc tctggaagcc
    10621 ccacttagtg gcttccatcc atgtctcatg ggacagaact gaatcacata gccatccctt
    10681 gctgtaagag agttggggaa agtattttaa gctgggacat cccagccctg agtgaagtca
    10741 gggatctgtt aggaagaatg gatgctaggt aggtaaatgg caatgtctga caaagacatg
    10801 gtaggccagt ctgaaaaatg taaagctggg ctgcgcgcgg tggctcacgc ctgaaatccc
    10861 agcactttgg gaggccgagg cgggcggatc ctgaggtcag gagatcgaga ccatcctggt
    10921 taacgtggtg aaaccccgtc tctactaaac atataaaaaa ttagccgggc ttggtggcgg
    10981 gcgcctgtag tcccagctac tgaggcagga gagtggcatg aacccgggag gcggagattg
    11041 cagtgagccg agatcgcgcc actgcactcc agcctgggtg acaaggcaag actccgtctc
    11101 aaaaaaaaaa agaaaaatat aaagctggat ctatacctca ctccttatac caaagtacat
    11161 tacccttgta tcaaatattt taaaaactgg aataagcttt tcatataatc tttgagaaga
    11221 tggggctttc aaagcgttaa atgaaacaca gaagccatgg ccaggcacgg tggctcatgc
    11281 ctgtaatccc agctctcagg gaggcaagag gcaggagcat agcttgagcc caggcgttca
    11341 agacctgcct gggcaatata gcgagacccc gttctcccca aaaaggaaaa aaaaaaaaaa
    11401 accaaaaaaa aaaaaaaagt ataaagcaca gaagcgaaag gaaaagtgat gaagacactt
    11461 gaagacctgt catttaaaat gattctacag gaaaaagatg aactacaaat tggggaaaaa
    11521 tatttgtagg acttatgtag acaaaggact aattttctta ataaaaacat ttatcagtaa
    11581 atttaaatgg gcaaaggaaa tacttggaca atcatatcat gtatgtaata ttaatattta
    11641 taaatcaata aaatgggcta gggatataaa tcagcaattc aaggggaggg taaaaagacc
    11701 aactaatata tgtaaagatg cacaaattca ttcatgatta aatgtgaatt aacaacgttg
    11761 gcctctcgga ttcccaaaac tttaaaagat taataatatc cagtattggt tgggattata
    11821 agcagatatg atatttcact gatagagacc agcatgactg tctcaattgt taaactattg
    11881 aaatgcatct gtgtcaatgg taaatagtat tattgtaagt acaacactaa aattaataaa
    11941 ttgtgtaaat tctaa
//
