LOCUS       NM_001375847            4792 bp    mRNA    linear   PRI 02-DEC-2022
DEFINITION  Homo sapiens XRCC1 N-terminal domain containing 1, N-terminal like
            (XNDC1N), transcript variant 1, mRNA.
ACCESSION   NM_001375847
VERSION     NM_001375847.2
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 4792)
  AUTHORS   Frankenberg S, Schneider NY, Fletcher TP, Shaw G and Renfree MB.
  TITLE     Identification of two distinct genes at the vertebrate TRPC2 locus
            and their characterisation in a marsupial and a monotreme
  JOURNAL   BMC Mol Biol 12, 39 (2011)
   PUBMED   21854574
  REMARK    Publication Status: Online-Only
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AP002490.4 and AP002495.3.
            
            On Nov 20, 2020 this sequence version replaced NM_001375847.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR1660807.241021.1,
                                           DRR138524.549652.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA1965299,
                                           SAMEA1966682 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000679412.2/ ENSP00000506430.1
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-230               AP002490.4         17589-17818         c
            231-397             AP002490.4         12533-12699         c
            398-539             AP002490.4         8109-8250           c
            540-695             AP002490.4         6845-7000           c
            696-874             AP002490.4         5298-5476           c
            875-4792            AP002495.3         110963-114880       c
FEATURES             Location/Qualifiers
     source          1..4792
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="11"
                     /map="11q13.4"
     gene            1..4792
                     /gene="XNDC1N"
                     /note="XRCC1 N-terminal domain containing 1, N-terminal
                     like"
                     /db_xref="GeneID:100133315"
                     /db_xref="HGNC:HGNC:54661"
     exon            1..230
                     /gene="XNDC1N"
                     /inference="alignment:Splign:2.1.0"
     exon            231..397
                     /gene="XNDC1N"
                     /inference="alignment:Splign:2.1.0"
     CDS             353..1057
                     /gene="XNDC1N"
                     /note="isoform 1 is encoded by transcript variant 1;
                     trpC2-like protein; XRCC1 N-terminal domain containing
                     1-like protein; putative short transient receptor
                     potential channel 2-like protein; protein XNDC1N"
                     /codon_start=1
                     /product="protein XNDC1N isoform 1"
                     /protein_id="NP_001362776.1"
                     /db_xref="CCDS:CCDS91528.1"
                     /db_xref="GeneID:100133315"
                     /db_xref="HGNC:HGNC:54661"
                     /translation="MAPVKISHVVSFSSQDPKYPVENLLNPDSPRRPWLGCPQDKSGQ
                     LKVELQLERAVPTGYIDVGNCGCAFLQIDVGHSSWPLDRPFITLLPATTLMSLTDSKQ
                     GKNRSGVRMFKDVDFLAPASGELWDRLRLTCSRPFTRHQSFGLAFLRVCSSLDSLDDS
                     VVGPSALLSSVLNKIREFKTCFFSWSLKKMELEFSPLLLSINLNDLQFAADAEVSTVS
                     NCMFISIALQSAMIIF"
     exon            398..539
                     /gene="XNDC1N"
                     /inference="alignment:Splign:2.1.0"
     exon            540..695
                     /gene="XNDC1N"
                     /inference="alignment:Splign:2.1.0"
     exon            696..874
                     /gene="XNDC1N"
                     /inference="alignment:Splign:2.1.0"
     exon            875..4792
                     /gene="XNDC1N"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1169..1174
                     /regulatory_class="polyA_signal_sequence"
                     /gene="XNDC1N"
                     /note="hexamer: ATTAAA"
     polyA_site      1186
                     /gene="XNDC1N"
     regulatory      1246..1251
                     /regulatory_class="polyA_signal_sequence"
                     /gene="XNDC1N"
                     /note="hexamer: AATAAA"
     polyA_site      1276
                     /gene="XNDC1N"
                     /note="major polyA site"
     regulatory      4770..4775
                     /regulatory_class="polyA_signal_sequence"
                     /gene="XNDC1N"
                     /note="hexamer: AATAAA"
     polyA_site      4792
                     /gene="XNDC1N"
ORIGIN      
        1 acacggaaat gtattttcct ggctgcagca cctgccatct tgcctcggta ggactcattt
       61 tcaaaaacag cagcttcttg aagccccaga acgcattcct gtgctacgga agacggaaga
      121 gtagctctcg gggtcagaag gcgaaggtca gaaggccgaa ttggcgggag aataggtttg
      181 gtggtccgag atccgaggca acggtggctc ctcgaggtcc acggtcccgg gagtaatgtg
      241 aggattcttg cttttctgga agctaacaca tagtcagtgc caaagtagtg acagaagaaa
      301 tcttgagagg aagcattttt gtcttgtact tgaaacagct gctgggccca ccatggctcc
      361 tgtgaagatc agccatgtgg tatcattttc ttctcaggat cccaagtatc ctgtagagaa
      421 cttgctaaac ccagatagtc caaggagacc ttggctcggc tgccctcagg acaagagtgg
      481 gcaattgaaa gtagaactac agctggagag ggcagtgccc actggctaca ttgatgtggg
      541 taactgtggc tgtgcgttcc tgcaaattga tgtgggccat tcttcctggc ccctggacag
      601 acctttcata accctgctcc ctgcaaccac gctaatgtct ctaactgatt caaagcaggg
      661 gaagaaccgc tccggggtcc gcatgtttaa agatgttgat ttcctggctc cagcctcagg
      721 agagttatgg gatcgacttc gcctgacctg ctcccgaccc ttcacgcgtc atcagtcctt
      781 tggcctggcc tttctacggg tgtgttcttc tctggactcc ttagatgact ctgtggtggg
      841 tccctcagcc cttctgagct ctgtgctgaa caagataaga gagtttaaga catgtttttt
      901 ctcctggagt ctgaagaaga tggagttaga attttcacca cttcttttgt ccatcaattt
      961 gaatgatctt cagtttgcag cagatgctga agtcagcaca gtatctaatt gcatgttcat
     1021 cagcattgca cttcagtctg caatgataat attctgaagg acattcatca ttagaagtga
     1081 agcttctggc tttaaaaaga gaagacaaat tatatgacac aatattactt actttttatg
     1141 tttaaatgtc tgaaatgttt tataataaat taaaagcatt acagaacttt cccagaaaaa
     1201 caaaaacaac agcaaaagaa tgcaagagaa aaagtggaga tgctgaataa agacaaacga
     1261 tgatttcttc tgtaaagaga gtagtaaatg aggcagtagt tggaaatgta cagaatttta
     1321 aatgagaact attaccacat atttctacct aaaatgaatt atccagcttg ggggtggtgt
     1381 agagattcat aatgcaggaa ataatgttta atttctggag ttaaattctt aaaaaagtca
     1441 ttggggatgg aatctagtgt aagtggaggg gttggccttg aatcacagag tgaagagaag
     1501 gcagattatg gataaagata aaaccatgtg aagagatatg gtggtggaaa agtggaaaag
     1561 ctatctttgg ttgcttctct gttcttggtg aaatgagaaa aaagaatcct taattgagag
     1621 aaggggtcag aaggagttga gtcttagttc cagcttccca gtgtattcgg gctcaaggcc
     1681 atgtctcctt tactgaggaa gttactgaga tatggacagg agcctataac ccataatctc
     1741 ccataaatat tccctttaaa cataccaatc cttcccaaat ccttttgtta caatttataa
     1801 gttaaaatat ttgccatgac caacatcatg aaagtttctc cttatgtttt cttctataag
     1861 ttttacagtc tcaggtaatt atgtttaaat gtgtagttca ttttgaattg ctttttgtgt
     1921 gtagtgtaag atacaggccc agttttattc ttttgcatat gaatattcag ttttcttagt
     1981 accacgtatt gaagaaacca tcttttcccc attatatatt cttcgcatgt ttgttgaagg
     2041 ccagttgact ttataagtgt cagttgattt cttggccctc tattctcttc cagtggccta
     2101 tatgtctatc tttatcccag tagcacacag ttttgattac tctatcttta taatacattt
     2161 tgaaattaga aaatgtgatg cccctagctt tgtttttctt gctcattgtt ttgactattc
     2221 tgggtccttt gtggttttat atgaatttta aaattgtttt ttctatttct gtcaagagtg
     2281 ccattaggat tttgataggg attgtatata atctataaat tgctttgaat agtatggata
     2341 ttttaatatt attatgtctt ccaattcatg aacataggat atctttctac tgatttgtgt
     2401 cttctttaat ttctttcatg aatgtctgca atttttaatg taccagtctt tcatcttttg
     2461 gttaagttta ttcttaaata tcttatcttt ttcttgctat tatgaatggg attttcttta
     2521 cttgctttcc agttgcttgc tgttagtgct atagaaacac aactggtatt tgtaggttga
     2581 ttttctatcc tgcaacttta ctgaatttgt tattagtttt aataattttg ggggagtgaa
     2641 gtttagggtt ttttacaaaa aaattatgtc atttggaaat agataatttt actcattccc
     2701 accccccaac agtttggatg ccatttattt ccttttcttg cctaattgtt cttgctagaa
     2761 cttttagaat catgttaaat aaatgtggca agaaggggca cttttgcctt gttcctgatc
     2821 ttagaagaaa agcttttagt ttttcaccat tgagtatgag tgaagaattt ctttttactt
     2881 ttattgtaag gtaggactac tggtgacaaa ctctattttt ggttacctaa gaaaattatg
     2941 tatttttact ttaatttaga gggtaggctg ggcatggtgg cctgcacctt taatcctggc
     3001 actttgggag gccaaggcgg gcagatcacc tggggtcagg ggttcaagac cagcctggcc
     3061 aaactagtga aacccagtct ctactaaaaa tacaaaatta gccaggcgtg gtggtggctg
     3121 gctgaggcac gagattgctt ggacccagga agcggaggct gcagtgagcc aaggtcactg
     3181 ccactgcact ccagcctggg tgacaaagtg agactctgtc taaaaaaaaa agataatttt
     3241 gctaagtaga gagttttaag atagtgttct tttttttttt ttaacatttt aaatatttca
     3301 ctttcctctc tttttgctta tgtggtttaa gagaagtctg atgtaattct tatccttggt
     3361 tgtccataga taaagatttt ttcccctcct ggcttctttt aagattttct tttcgtcttt
     3421 gatttttggc agtttcaata taatatgcct atgtttaaat tttttgtatt tatcttgctt
     3481 ggtattctct cagcttccta gatatgtaga ttttgtttat tttcaatttt gggaaaatct
     3541 cagtcagaat ttcttcaaat atttcttctg ttcctttctt tctcctcctc ctgatacttc
     3601 attacacata tatttttcct tttctaattg gcctacactt attaaatatt ctgttctttt
     3661 taattctttt ttctttgctt ttaagttttg gaagttgcta tttaaaattc tttaagctca
     3721 ctgattcttt ccttgatcat atcagtctat tgatgaattc attgttatgg gctaaccagt
     3781 tttcctccaa aatttgtatg ttaaagtccc aatctttagt atctcagaat gtaatcatat
     3841 ttgaagattt ttttttttta aggactgata aagctaaaat gagactccca gggtatggcc
     3901 ctcgtgcaat atggctgatg tccttattag aagaggaaga gacaccagga attcatgtgc
     3961 acaaaaaaat gccataagag gacatggcaa gaaggcaacc agctgcaagc caagacaggc
     4021 ctcaggagaa accaaatgtg ctgacgtctt gatcttagac ttataacttc cagaactgtg
     4081 agaaaatgaa cttttgttat ttaaggcacc cattatgtgg tactttatta tgataaccct
     4141 atagcaatgc aagaatggcc taatacatct atatttatat tggacaaaat tgactttaag
     4201 tgaaaaaaca taaaaagaga caaagaaggc catcatataa tgataaaagg gccaatccag
     4261 caagaggata taaaaattcc aaatatgtat atatatgtac ccagtagtgg aatagatata
     4321 ttaaaaatgt cattagagct aaagagagag atacacctca acatcatgat aactgagggc
     4381 ttcaataccc cactttcagc attgaacaga tcatctaggt agaaagctaa caaataatca
     4441 tcaaatttaa tctgtaccac agaacaaata gacttaacag acatttacac aacatttcat
     4501 ccaaaagctg tggagtacac attcttctcc tcatcacaca gaacattctc caggctagac
     4561 catatgttaa gacacaaaac aagtttcaac aaattttgaa aaatcaacat tatatcaagt
     4621 atattctaga caaaaataga atagaactag aaatgaatac taggaagaac tttggaaact
     4681 atacagataa catggaaatt aaacaacatg cttctgaaca accattgagt caatgaaaaa
     4741 actcagaaga aaataacaaa tgttcttgaa ataaatgcaa atggaaacac aa
//
