LOCUS       XM_011534491            7319 bp    mRNA    linear   PRI 25-AUG-2024
DEFINITION  PREDICTED: Homo sapiens WW and C2 domain containing 1 (WWC1),
            transcript variant X7, mRNA.
ACCESSION   XM_011534491
VERSION     XM_011534491.2
DBLINK      BioProject: PRJNA168
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_000005.10) annotated using gene prediction method: Gnomon,
            supported by mRNA and EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            On Apr 5, 2022 this sequence version replaced XM_011534491.1.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_000001405.40-RS_2024_08
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           RefSeqFE; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 08/23/2024
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7319
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="5"
     gene            1..7319
                     /gene="WWC1"
                     /gene_synonym="HBEBP3; HBEBP36; KIBRA; MEMRYQTL; PPP1R168"
                     /note="WW and C2 domain containing 1; Derived by automated
                     computational analysis using gene prediction method:
                     Gnomon. Supporting evidence includes similarity to: 1
                     mRNA, 38 ESTs, 418 long SRA reads, 2 Proteins, and 94%
                     coverage of the annotated genomic feature by RNAseq
                     alignments, including 17 samples with support for all
                     annotated introns"
                     /db_xref="GeneID:23286"
                     /db_xref="HGNC:HGNC:29435"
                     /db_xref="MIM:610533"
     CDS             509..4033
                     /gene="WWC1"
                     /gene_synonym="HBEBP3; HBEBP36; KIBRA; MEMRYQTL; PPP1R168"
                     /codon_start=1
                     /product="protein KIBRA isoform X7"
                     /protein_id="XP_011532793.1"
                     /db_xref="GeneID:23286"
                     /db_xref="HGNC:HGNC:29435"
                     /db_xref="MIM:610533"
                     /translation="MPRPELPLPEGWEEARDFDGKVYYIDHTNRTTSWIDPRDRYTKP
                     LTFADCISDELPLGWEEAYDPQVGDYFIDHNTKTTQIEDPRVQWRREQEHMLKDYLVV
                     AQEALSAQKEIYQVKQQRLELAQQEYQQLHAVWEHKLGSQVSLVSGSSSSSKYDPEIL
                     KAEIATAKSRVNKLKREMVHLQHELQFKERGFQTLKKIDKKMSDAQGSYKLDEAQAVL
                     RETKAIKKAITCGEKEKQDLIKSLAMLKDGFRTDRGSHSDLWSSSSSLESSSFPLPKQ
                     YLDVSSQTDISGSFGINSNNQLAEKVRLRLRYEEAKRRLSCQCGQATPSNSELTHYQL
                     PQASSKTARHLYLDSHFLFSLKRTTLNLGSVPSCRNACLRWIANLKIQLAKLDSEAWP
                     GVLDSERDRLILINEKEELLKEMRFISPRKWTQGEVEQLEMARKRLEKDLQAARDTQS
                     KALTERLKLNSKRNQLVRELEEATRQVATLHSQLKSLSSSMQSLSSGSSPGSLTSSRG
                     SLVASSLDSSTSASFTDLYYDPFEQLDSELQSKVEFLLLEGATGFRPSGCITTIHEDE
                     VAKTQKAEGGGRLQALRSLSGTPKSMTSLSPRSSLSSPSPPCSPLMADPLLAGDAFLN
                     SLEFEDPELSATLCELSLGNSAQERYRLEEPGTEGKQLGQAVNTAQGCGLKVACVSAA
                     VSDESVAGDSGVYEASVQRLGASEAAAFDSDESEAVGATRIQIALKYDEKNKQFAILI
                     IQLSNLSALLQQQDQKVNIRVAVLPCSESTTCLFRTRPLDASDTLVFNEVFWVSMSYP
                     ALHQKTLRVDVCTTDRSHLEECLGGAQISLAEVCRSGERSTRWYNLLSYKYLKKQSRE
                     LKPVGVMAPASGPASTDAVSALLEQTAVELEKRQEGRSSTQTLEDSWRYEETSENEAV
                     AEEEEEEVEEEEGEEDVFTEKASPDMDGYPALKVDKETNTETPAPSPTVVRPKDRRVG
                     TPSQGPFLRGSTIIRSKTFSPGPQSQYVCRLNRSDSDSSTLSKKPPFVRNSLERRSVR
                     MKRPSSVKSLRSERLIRTSLDLELDLQATRTWHSQLTQEISVLKELKEQLEQAKSHGE
                     KELPQWLREDERFRLLLRMLEKRQMDRAEHKGELQTDKMMRAAAKDVHRLRGQSCKEP
                     PEVQSFREKMAFFTRPRMNIPALSADDV"
ORIGIN      
        1 gtttccgggg cagcgcggtt acctgcaccg cccgagccgc acctggcgga ggcagaagtc
       61 acaaacccgg cgagctcaga gcggtggagc ggagaggagg gacggcaccc ggctgcaggg
      121 aggagggagg cggcagcggc agcggcggcg tggagggcgc agcgcgccgc gcggcggagg
      181 agggcagacg gcggcggcgg cggcgctcgg ctcgctctgc ccggccggct gggcgcgcac
      241 ccgggctcgc accgcgccgc tgcggacgca catggcagcg tgagaggccg gcggcgggag
      301 gagcgggcgg cgccgggtcg gggctgcagg gccgcatgga cagcggcgcc accccggccg
      361 gcccctacta gggcccccca tctgcgggcg ccaccccccg gatcatggtg cctcggcggc
      421 cgcccgggct aagagcggcc ggctggagcc gctgagcccc cgctgcggcc gggagctgca
      481 tgggggagcg ccggcagcgc ttgggaagat gccccggccg gagctgcccc tgccggaggg
      541 ctgggaggag gcgcgcgact tcgacggcaa ggtctactac atagaccaca cgaaccgcac
      601 caccagctgg atcgacccgc gggacaggta caccaaaccg ctcacctttg ctgactgcat
      661 tagtgatgag ttgccgctag gatgggaaga ggcatatgac ccacaggttg gagattactt
      721 catagaccac aacaccaaaa ccactcagat tgaggatcct cgagtacaat ggcggcggga
      781 gcaggaacat atgctgaagg attacctggt ggtggcccag gaggctctga gtgcacaaaa
      841 ggagatctac caggtgaagc agcagcgcct ggagcttgca cagcaggagt accagcaact
      901 gcatgccgtc tgggagcata agctgggctc ccaggtcagc ttggtctctg gttcatcatc
      961 cagctccaag tatgaccctg agatcctgaa agctgaaatt gccactgcaa aatcccgggt
     1021 caacaagctg aagagagaga tggttcacct ccagcacgag ctgcagttca aagagcgtgg
     1081 ctttcagacc ctgaagaaaa tcgataagaa aatgtctgat gctcagggca gctacaaact
     1141 ggatgaagct caggctgtct tgagagaaac aaaagccatc aaaaaggcta ttacctgtgg
     1201 ggaaaaggaa aagcaagatc tcattaagag ccttgccatg ttgaaggacg gcttccgcac
     1261 tgacaggggg tctcactcag acctgtggtc cagcagcagc tctctggaga gttcgagttt
     1321 cccgctaccg aaacagtacc tggatgtgag ctcccagaca gacatctcgg gaagcttcgg
     1381 catcaacagc aacaatcagt tggcagagaa ggtcagattg cgccttcgat atgaagaggc
     1441 taagagaaga ctttcctgtc aatgtggcca ggcaactccc agcaattcgg agcttacaca
     1501 ctaccagctc ccccaggcgt ccagcaaaac agcaagacat ctgtatttgg acagccactt
     1561 cttgttctct ctgaagagga ccactctgaa ccttggatct gttccatcct gcaggaatgc
     1621 ctgtcttaga tggatcgcca acctgaagat ccagctggcc aagcttgaca gtgaggcctg
     1681 gcctggggtg ctggactcag agagggaccg gctgatcctt atcaacgaga aggaggagct
     1741 gctgaaggag atgcgcttca tcagcccccg caagtggacc cagggggagg tggagcagct
     1801 ggagatggcc cggaagcggc tggaaaagga cctgcaggca gcccgggaca cccagagcaa
     1861 ggcgctgacg gagaggttaa agttaaacag taagaggaac cagcttgtga gagaactgga
     1921 ggaagccacc cggcaggtgg caactctgca ctcccagctg aaaagtctct caagcagcat
     1981 gcagtccctg tcctcaggca gcagccccgg atccctcacg tccagccggg gctccctggt
     2041 tgcatccagc ctggactcct ccacttcagc cagcttcact gacctctact atgacccctt
     2101 tgagcagctg gactcagagc tgcagagcaa ggtggagttc ctgctcctgg agggggccac
     2161 cggcttccgg ccctcaggct gcatcaccac catccacgag gatgaggtgg ccaagaccca
     2221 gaaggcagag ggaggtggcc gcctgcaggc tctgcgttcc ctgtctggca ccccaaagtc
     2281 catgacctcc ctatccccac gttcctctct ctcctccccc tccccaccct gttcccctct
     2341 catggctgac cccctcctgg ctggtgatgc cttcctcaac tccttggagt ttgaagaccc
     2401 ggagctgagt gccactcttt gtgaactgag ccttggtaac agcgcccagg aaagataccg
     2461 gctggaggaa ccaggaacgg agggcaagca gctgggccaa gctgtgaata cggcccaggg
     2521 gtgtggcctg aaagtggcct gtgtctcagc cgccgtatcg gacgagtcag tggctggaga
     2581 cagtggtgtg tacgaggctt ccgtgcagag actgggtgct tcagaagctg ctgcatttga
     2641 cagtgacgaa tcggaagcag tgggtgcgac ccgaattcag attgccctga agtatgatga
     2701 gaagaataag caatttgcaa tattaatcat ccagctgagt aacctttctg ctctgttgca
     2761 gcaacaagac cagaaagtga atatccgcgt ggctgtcctt ccttgctctg aaagcacaac
     2821 ctgcctgttc cggacccggc ctctggacgc ctcagacact ctagtgttca atgaggtgtt
     2881 ctgggtatcc atgtcctatc cagcccttca ccagaagacc ttaagagtcg atgtctgtac
     2941 caccgacagg agccatctgg aagagtgcct gggaggcgcc cagatcagcc tggcggaggt
     3001 ctgccggtct ggggagaggt cgactcgctg gtacaacctt ctcagctaca aatacttgaa
     3061 gaaacagagc agggagctca agccagtggg agtcatggcc cctgcctcag ggcctgccag
     3121 cacggacgct gtgtctgctc tgttggaaca gacagcagtg gagctggaga agaggcagga
     3181 gggcaggagc agcacacaga cactggaaga cagctggagg tatgaggaga ccagtgagaa
     3241 tgaggcagta gccgaggaag aggaggagga ggtggaggag gaggagggag aagaggatgt
     3301 tttcaccgag aaagcctcac ctgatatgga tgggtaccca gcattaaagg tggacaaaga
     3361 gaccaacacg gagaccccgg ccccatcccc cacagtggtg cgacctaagg accggagagt
     3421 gggcaccccg tcccaggggc catttcttcg agggagcacc atcatccgct ctaagacctt
     3481 ctccccagga ccccagagcc agtacgtgtg ccggctgaat cggagtgata gtgacagctc
     3541 cactctgtcc aaaaagccac cttttgttcg aaactccctg gagcgacgca gcgtccggat
     3601 gaagcggcct tcctcggtca agtcgctgcg ctccgagcgt ctgatccgta cctcgctgga
     3661 cctggagtta gacctgcagg cgacaagaac ctggcacagc caattgaccc aggagatctc
     3721 ggtgctgaag gagctcaagg agcagctgga acaagccaag agccacgggg agaaggagct
     3781 gccacagtgg ttgcgtgagg acgagcgttt ccgcctgctg ctgaggatgc tggagaagcg
     3841 gcagatggac cgagcggagc acaagggtga gcttcagaca gacaagatga tgagggcagc
     3901 tgccaaggat gtgcacaggc tccgaggcca gagctgtaag gaacccccag aagttcagtc
     3961 tttcagggag aagatggcat ttttcacccg gcctcggatg aatatcccag ctctctctgc
     4021 agatgacgtc taatcgccag aaaagtattt cctttgttcc actgaccagg ctgtgaacat
     4081 tgactgtggc taaagttatt tatgtggtgt tatatgaagg tactgagtca caagtcctct
     4141 agtgctcttg ttggtttgaa gatgaaccga ctttttagtt tgggtcctac tgttgttatt
     4201 aaaaacagaa caaaaacaaa acacacacac acacaaaaac agaaacaaaa aaaaccagca
     4261 ttaaaataat aagattgtat agtttgtata tttaggagtg tatttttggg aaagaaaatt
     4321 taaatgaact aaagcagtat tgagttgctg ctcttcttaa aatcgtttag attttttttg
     4381 gtttgtacag ctccaccttt tagaggtctt actgcaataa gaagtaatgc ctgggggacg
     4441 gtaatcctaa taggacgtcc cgcacttgtc acagtacagc taatttttcc tagttaacat
     4501 attttgtaca atattaaaaa aatgcacaga aaccattggg ggggattcag aggtgcatcc
     4561 acggatcttc ttgagctgtg acgtgttttt atgtggctgc ccaacgtgga gcgggcagtg
     4621 tgataggctg ggtgggctaa gcagcctagt ctatgtgggt gacaggccac gctggtctca
     4681 gatgcccagt gaagccacta acatgagtga ggggagggct gtggggaact ccattcagtt
     4741 ttatctccat caataaagtg gcctttcaaa aagaatcttc ctcttgctct ctttttcttt
     4801 cctacccctc acttcatctg tttccctgat ttttgactct cccctttcca gtcatttctt
     4861 tcccacccat ccgcagtcct ggaaacattt attttttctt ttgcccactg ttttcatttg
     4921 ctcattaaat taaaatgact gctcggctca ttgggaatcc acatccccaa gttagactgg
     4981 ggatatgctc tctgtactgt ctccttctat ggaattccac cccacccaga gagagatgac
     5041 ttcacagttt gttcatatga gcatcatccc atgtcgtccc caacccaggg gctggtaggt
     5101 gctacagctt gtgcttcatg ctgctcctgt ggcccctatt cctacccagc tcagagcttt
     5161 gcagggtcta ctgcagacaa tcagaagtca gtttctaaca aatagcaaca gccacaaatc
     5221 tcttcctcct tcctctctga cattaccctg tgcaactttt ctcaaagtct gttgcaccac
     5281 tcagcaaagc aagttgcacc agctatatca gaatcacctg gggcagccta ttaaaaatgc
     5341 agactgttga gaccatcctg gctaacacgg tgaaaccctg tctctactaa aaatacaaaa
     5401 aattagccgg ccgtggtggc gggcagctac tcgggaggct gaggcaggag aatgacctga
     5461 acctgggagg cagagcttgc agtgagctga gattgtgcca ctgcactcca gcctgggtga
     5521 cagagcaaga ctccgtctca aaaaaaaaaa aaaaagaaaa atgcagactg gctggcgcgg
     5581 tggctcatgc ttgtaatccc agcactttgg gaggctgagg cgggcagatc aactgagatc
     5641 gggggttcga gaccagcctg atcaacatgg agaaacctgg tctctactaa aaatacataa
     5701 ttagctgggc gtagtggcgc atacctgtaa tcccagctac ttgggtggcc aaggcttgaa
     5761 cccaggaggc ggaggttgcg gtgagccgag atggcgccat tgactccagc ctgggcaaca
     5821 agagcgtaac tccatctcaa aaaaataata ataataaaaa taaaatgcag actgtcaggt
     5881 cctctctaga cccactgaac tatcccgccc accctgggac ggtccccagt gccagtgttt
     5941 tacccatgtt ccctctgtaa gtcttatgca caccgcaatt tgagagcccc actggtataa
     6001 agtgagtgaa acccaggcag agacaggcaa aatggtgagg cccgcatcct attggtgagt
     6061 cacacaggga acgctgaaat tcatggcctt ctccaggcta ctgggaaccc atgggcggtg
     6121 atggagggag tggtgccacc ttcacttgct gctgaggctc ttccccctct ccccagcata
     6181 ctccttacct ggctgtctct cctcatgtat aaggaaccta tagtggtgta gaatctactc
     6241 ttcttccccc tgtggcttcc aggcccccct gtatagctgc tatccagccc gatttctcac
     6301 cactggccca gggcttcctc ctgccccgtg gcttcacgtc tctgaacaca tcaatctctg
     6361 atgttctctc tccttccatt gaattccacc agacacattc agggtttact tcgtaatgtc
     6421 ttcatatgag tatcaatcaa caccttcccc aactcaattg tactaggttg tagagcacaa
     6481 ggatggtctc gtgctgctct gtggcacctg tgcctacact cctctgagct ttgaggaggc
     6541 tgctctcttt gctgacccca tgatcttttc tgcccttctg ttaagggcat tggccacagc
     6601 aacggggcaa atgccccaag ctggctgtaa gtgacccatc cctttggctc ccatgattag
     6661 accaaggaga ggcatggggt ccagctgagc cattcagaac cattccttag cattttccac
     6721 tcaaaggtta gagatgagat tttctcttcc caaggctacc tctggccatg gttccagctt
     6781 catgggggca atgggattag gaaaatgagg tcaacctgca aaggaaagca gatgcaagag
     6841 atggagacag aatgggggtg tcctggggat cttggagcct gaattcattg gcacaaaagg
     6901 cagcagcatc ctcactgtat ctgcagtcca tttggactca ataaaaactt tgaaagtcac
     6961 atgtgttatg gaattccttc tcagtgacac attcatctgt gctcagttgt cccagcaagg
     7021 gtcagcccct catacccctg cagcatccgc tgctatgaag cagagctgta aacgccctcc
     7081 ctgtgtatag gaaaagctac atggagcaaa tcctcctgcc tgaagaagtg catctcagca
     7141 tcacttcagc tgtcggggca tttgtgggga gaaccagacc acctctgcgg aaggcagcag
     7201 accctcttcc agccatggat ggagttgaat tctctataaa cggttcacca gcaaaccacc
     7261 aatacattcc attgtttgcc tagagagaaa tttaaaaata aataaatgtt cacttataa
//
