LOCUS       XM_006715685            4323 bp    mRNA    linear   PRI 25-AUG-2024
DEFINITION  PREDICTED: Homo sapiens WD repeat domain, phosphoinositide
            interacting 2 (WIPI2), transcript variant X1, mRNA.
ACCESSION   XM_006715685
VERSION     XM_006715685.2
DBLINK      BioProject: PRJNA168
KEYWORDS    RefSeq; includes ab initio.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_000007.14) annotated using gene prediction method: Gnomon,
            supported by mRNA and EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            On Apr 5, 2022 this sequence version replaced XM_006715685.1.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_000001405.40-RS_2024_08
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           RefSeqFE; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 08/23/2024
            ##Genome-Annotation-Data-END##
            
            ##RefSeq-Attributes-START##
            ab initio :: 19% of CDS bases
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..4323
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="7"
     gene            1..4323
                     /gene="WIPI2"
                     /gene_synonym="ATG18B; Atg21; CGI-50; IDDSSA; WIPI-2"
                     /note="WD repeat domain, phosphoinositide interacting 2;
                     Derived by automated computational analysis using gene
                     prediction method: Gnomon. Supporting evidence includes
                     similarity to: 3 mRNAs, 58 ESTs, 885 long SRA reads, 1
                     Protein, and 95% coverage of the annotated genomic feature
                     by RNAseq alignments, including 56 samples with support
                     for all annotated introns"
                     /db_xref="GeneID:26100"
                     /db_xref="HGNC:HGNC:32225"
                     /db_xref="MIM:609225"
     CDS             483..1415
                     /gene="WIPI2"
                     /gene_synonym="ATG18B; Atg21; CGI-50; IDDSSA; WIPI-2"
                     /codon_start=1
                     /product="WD repeat domain phosphoinositide-interacting
                     protein 2 isoform X1"
                     /protein_id="XP_006715748.1"
                     /db_xref="GeneID:26100"
                     /db_xref="HGNC:HGNC:32225"
                     /db_xref="MIM:609225"
                     /translation="MKVLHTIRETPPNPAGLCALSINNDNCYLAYPGSATIGEVQVFD
                     TINLRAANMIPAHDSPLAALAFDASGTKLATASEKGTVIRVFSIPEGQKLFEFRRGVK
                     RCVSICSLAFSMDGMFLSASSNTETVHIFKLETVKEKPPEEPTTWTGYFGKVLMASTS
                     YLPSQVTEMFNQGRAFATVRLPFCGHKNICSLATIQKIPRLLVGAADGYLYMYNLDPQ
                     EGGECALMKQHRLDGSLETTNEILDSASHDCPLVTQTYGAAAGKGTYVPSSPTRLAYT
                     DDLGAVGGACLEDEASALRLDEDSEHPPMILRTD"
ORIGIN      
        1 gtaccgggtg ccccggctct ggagcataaa caagagcggg gacgggatga ggcggcggtt
       61 gatcccaggg tggcgagtgg cggcgaccga ggcggcgagc ggggcccggc gccgaccctg
      121 agtgcagcct gacccgccct cgcgcgcgcg ccctccccgg ccgggcccac tcgccgcgcg
      181 cccagccatg aacctggcga gccagagcgg ggaggccggc gccggccagc tgctcttcgc
      241 caacttcaac caggacaaca cccgatacgg aagatgtgtg cattgtagag agattgttct
      301 ccagcagcct agtggccatc gtcagcctta aagcaccaag gaagctaaag gtttgccact
      361 ttaagaaggg aactgagatc tgcaactaca gctactccaa cacgattctg gctgtgaagc
      421 tcaacaggca gaggctgata gtatgcctgg aggagtccct gtacatccac aacattcggg
      481 acatgaaggt gctgcatacg atcagggaga cgcctccaaa ccctgcaggc ctgtgtgcgc
      541 tgtcaatcaa caacgacaac tgctacttgg cgtacccagg gagcgcgacc atcggagagg
      601 tgcaggtctt cgataccatt aatttgagag ctgcaaacat gattccggct cacgacagtc
      661 ctttagcggc actggccttt gacgcaagtg gaactaaact tgccacggct tcggagaagg
      721 ggaccgtgat tagggtattt tccattccag aaggacaaaa actctttgag tttcggagag
      781 gagtaaagag gtgcgtgagc atctgctccc tggccttcag catggacggc atgttcctct
      841 ccgcctccag caacactgag accgtgcaca tcttcaaact cgagactgtg aaagaaaaac
      901 ccccagagga gcccaccacc tggaccgggt acttcgggaa agtgctcatg gcctccacca
      961 gctacctgcc ttcccaagtg acagaaatgt tcaaccaggg cagagccttc gccacggtcc
     1021 gcctgccatt ctgcggccac aaaaacatct gctcgctagc cacaattcag aagatcccgc
     1081 ggttgttggt gggtgccgcc gacgggtacc tgtacatgta caacctggac ccccaggagg
     1141 gcggcgagtg tgccctgatg aagcagcacc ggctggacgg cagtctggaa acgaccaatg
     1201 agatcttgga ctctgcctct cacgactgcc ccttagtcac tcagacatac ggcgcagctg
     1261 caggaaaagg tacttacgtg ccttcatccc caacgagact tgcctacaca gacgacctgg
     1321 gtgctgtggg tggcgcctgc ctggaggacg aggccagcgc cctgcgcctg gatgaggaca
     1381 gcgagcaccc gcccatgatt cttcggactg actgaacttg acctgtgacc tctgacccgg
     1441 ggagcagaga acactggctt cacagaggac tttgtgcatt gctgctatga actttgacct
     1501 gagtcggggg agaggatggc agagacttta ttaaaaaaaa aaaaagattg tagtggtagt
     1561 ctaactccat aacgctgagg aaatacatca ttttcacttc agtggctttt aaatcctgct
     1621 tatgaatttt agctttttgt ttgtttgttt tctctttttg ccaaaattaa ctgtttggtg
     1681 aagcccgcaa aacctcctcg ctttgcatgc atgaacgtgc caagccagca taggggagct
     1741 agaagccact ttccagccac ctgccgttgg gttttttcat atctgtacat aatgccgagt
     1801 gcgtaaggaa accgtggcgt cgcgcacagt gggtctgctt gtcaaggcca gttctgcagt
     1861 gacaggccca ggggctgccc accaggtgtg ctgggcagac ttcagctggg acagaagtcc
     1921 gatctcccta gggccccacc tggaccattt tccctccgtt ttattttgtt aattaaattc
     1981 tttccaaatt ggatcgctct gggatttctt ccatggtgga cttttgtttc tgatcttgtt
     2041 ttccctgtgg atattggagg acagcgaggt tctttctgat actaaaaacc tttctttcag
     2101 gcagcaaatg aacttgaaag gttgcctgga ctcgctggag caaaggaaag cgattttgtt
     2161 tgtataatta aatgatctgt tcttctactt cactcttcct gttgaaaaac tgtgtgattt
     2221 tttttttttt ttaagtaaag tttgtagctc ctcccatgcc caggaaagca cagaactcaa
     2281 gtgtggtggc cgtctgagct gtcctttcgc tggccccgct gtccgcaggg gcttcctacc
     2341 tgtgtgagag gtcgtagcgg gagacagcaa cagagagtag gcggctgggc cacgtccttc
     2401 acagggcgtc atgtgccttt ctattttcat cttagaaaat ttcctcagca aaccgatgag
     2461 agattgtggt tgcaagcttc agtatttgcc tcgcttccct tcccttttca tatttacaga
     2521 attaaaacaa cctcaagtac ctcagactct gcattccaaa ccaaggcacc cagcagccaa
     2581 agtgtcgagg gcatttaagt ggcattaatg gcaggagaga tggttttaga atctatggag
     2641 tggtggaagt tacggataga agggaaaagg caaaaactat ttaccctgcc tttgcaggct
     2701 ggggtttttg aaccgaggaa ggctgggacg cctgtttcca gatggttgtc atggtcacgc
     2761 tgggcgaaga gctggagggg agttgtcccc tcagctgagc ggctgcggtg aaatgcccca
     2821 gtgttcctgg gttggcttta cggcaaacta aatgcagggg acgctggagt ccgactcacc
     2881 tacaccggct tcctcccagc cgctggtgtg cggcacacac aacatctgca ttaggcagag
     2941 gtgcaagtgg gctgattgaa cttttccttc aaaacctgct tgtctgtcct ggacctttga
     3001 tgaaatggga tcccggtcac gcaggctgag acagtgggga ccgccgaggc cagagtgggc
     3061 tatgcttgag cagggatgag aagggccgcg gcagcacgca gccttgaccc acgcctgcgt
     3121 cttgtggtgc aaggccagag ggctctctct agaacctgac cgtgcactcc atctcctggg
     3181 agccactttt ggcaagagtg agtgtggggg gaaaaagtgt gcacaagaga tacggaaccc
     3241 tgagctaggg tttcctgtca ccaaagagtg agctgcattt ccagttctgc gttaaagtat
     3301 cgtttgttct ggtgcctgcc tgtggtggtg atttggagac tcaaatttcc tttgccaggt
     3361 ctcttttgtc tttctttggg attggtagta tagaagatgc tgggaattgt cttcctcgct
     3421 cagcctcggc ttcccgcact gtaagatgag gcagttgcag aggaggcctc ggacgtcctg
     3481 tgaccctcgg cccacactcc cccttgggtg gccctggcag ggctggctag gtgcgttccc
     3541 tgcagaccac gggaagccct gtgcttgcct gggtcagggc taagctgtgc gccctagagg
     3601 agggaggagg actgcagatt cttggtcgag aagaatgaag aggatttctg tgtttgctga
     3661 gcagccattg tggagggtta cccgcctcca ctttcccgtt gcccatttca ctgccaccag
     3721 ctcctcttcc tctgctcgaa cctatgagtc ccagcctcac tggcggcctc agacatgctc
     3781 aggagtgacg gggacagagg gaggccgctg agttgcccgt tagaactctt actgctgcgc
     3841 cagtgaccca ggtggagagg gaccctgaac caaacagaac gtgtgctaat tttccgaact
     3901 ccaaactgta cactcatatt catttttaaa ttgtattttt ccaaacttca aaaaggacga
     3961 tgagcgtggg ggataggaaa caaaacctgt aaacgttgtg aatgggctca gtggactctg
     4021 ggaccaaacc ttctgtaatc tctaaaacaa tgggaccaag agctggatgg aacctggagt
     4081 caaaaagaac tgcttcagtc cccgctgtac cgcctgccta gctgtgggag caggcagggc
     4141 gcctgggagc ctgcgttttc tggaccgttc catgggactc atccctacct cacagggctg
     4201 ttgtgaggtg ttgtgtgact gcgtgtcctg caaacgccca gctcggtgcc cagccagcgg
     4261 tgggcaccca ataaacgcta caacataaat gtgtcttctg caattaaaca cgatttttat
     4321 tca
//
