LOCUS       NM_001039500            9143 bp    mRNA    linear   PRI 03-OCT-2024
DEFINITION  Homo sapiens von Willebrand factor A domain containing 5B1
            (VWA5B1), transcript variant 1, mRNA.
ACCESSION   NM_001039500 XM_001720309 XM_001722222 XM_001722706
VERSION     NM_001039500.3
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 9143)
  AUTHORS   Rose,J.E., Behm,F.M., Drgon,T., Johnson,C. and Uhl,G.R.
  TITLE     Personalized smoking cessation: interactions between nicotine dose,
            dependence and quit-success genotype score
  JOURNAL   Mol Med 16 (7-8), 247-253 (2010)
   PUBMED   20379614
  REMARK    GeneRIF: Clinical trial of gene-disease association and
            gene-environment interaction. (HuGE Navigator)
            Erratum:[Mol Med. 2012;18(1):729]
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL020998.1.
            
            On Dec 8, 2018 this sequence version replaced NM_001039500.2.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            RNAseq introns :: single sample supports all introns SAMEA1968968,
                              SAMEA2144335 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000289815.13/ ENSP00000289815.9
            RefSeq Select criteria :: based on manual assertion, conservation,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-214               AL020998.1         9907-10120
            215-379             AL020998.1         29608-29772
            380-532             AL020998.1         31868-32020
            533-803             AL020998.1         33354-33624
            804-949             AL020998.1         36562-36707
            950-1081            AL020998.1         37622-37753
            1082-1206           AL020998.1         38414-38538
            1207-1383           AL020998.1         42388-42564
            1384-1494           AL020998.1         46922-47032
            1495-1697           AL020998.1         49212-49414
            1698-1812           AL020998.1         49901-50015
            1813-1998           AL020998.1         51798-51983
            1999-2182           AL020998.1         55335-55518
            2183-2373           AL020998.1         56678-56868
            2374-2551           AL020998.1         61464-61641
            2552-2866           AL020998.1         62111-62425
            2867-3004           AL020998.1         64488-64625
            3005-3118           AL020998.1         67277-67390
            3119-3193           AL020998.1         69188-69262
            3194-3263           AL020998.1         69889-69958
            3264-3381           AL020998.1         71087-71204
            3382-9143           AL020998.1         72789-78550
FEATURES             Location/Qualifiers
     source          1..9143
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="1"
                     /map="1p36.12"
     gene            1..9143
                     /gene="VWA5B1"
                     /note="von Willebrand factor A domain containing 5B1"
                     /db_xref="GeneID:127731"
                     /db_xref="HGNC:HGNC:26538"
     exon            1..214
                     /gene="VWA5B1"
                     /inference="alignment:Splign:2.1.0"
     exon            215..379
                     /gene="VWA5B1"
                     /inference="alignment:Splign:2.1.0"
     CDS             241..3888
                     /gene="VWA5B1"
                     /note="isoform 1 precursor is encoded by transcript
                     variant 1; von Willebrand factor A domain-containing
                     protein 5B1"
                     /codon_start=1
                     /product="von Willebrand factor A domain-containing
                     protein 5B1 isoform 1 precursor"
                     /protein_id="NP_001034589.2"
                     /db_xref="GeneID:127731"
                     /db_xref="HGNC:HGNC:26538"
                     /translation="MPGLLNWITGAALPLTASDVTSCVSGYALGLTASLTYGNLEAQP
                     FQGLFVYPLDECTTVIGFEAVIADRVVTVQIKDKAKLESGHFDASHVRSPTVTGNILQ
                     DGVSIAPHSCTPGKVTLDEDLERILFVANLGTIAPMENVTIFISTSSELPTLPSGAVR
                     VLLPAVCAPTVPQFCTKSTGTSNQQAQGKDRHCFGAWAPGSWNKLCLATLLNTEVSNP
                     MEYEFNFQLEIRGPCLLAGVESPTHEIRADAAPSARSAKSIIITLANKHTFDRPVEIL
                     IHPSEPHMPHVLIEKGDMTLGEFDQHLKGRTDFIKGMKKKSRAERKTEIIRKRLHKDI
                     PHHSVIMLNFCPDLQSVQPCLRKAHGEFIFLIDRSSSMSGISMHRVKDAMLVALKSLM
                     PACLFNIIGFGSTFKSLFPSSQTYSEDSLAMACDDIQRMKADMGGTNILSPLKWVIRQ
                     PVHRGHPRLLFVITDGAVNNTGKVLELVRNHAFSTRCYSFGIGPNVCHRLVKGLASVS
                     EGSAELLMEGERLQPKMVKSLKKAMAPVLSDVTVEWIFPETTEVLVSPVSASSLFPGE
                     RLVGYGIVCDASLHISNPRSDKRRRYSMLHSQESGSSVFYHSQDDGPGLEGGDCAKNS
                     GAPFILGQAKNARLASGDSTTKHDLNLSQRRRAYSTNQITNHKPLPRATMASDPMPAA
                     KRYPLRKARLQDLTNQTSLDVQRWQIDLQPLLNSGQDLNQGPKLRGPGARRPSLLPQG
                     CQPFLPWGQETQAWSPVRERTSDSRSPGDLEPSHHPSAFETETSSDWDPPAESQERAS
                     PSRPATPAPVLGKALVKGLHDSQRLQWEVSFELGTPGPERGGAQDADLWSETFHHLAA
                     RAIIRDFEQLAEREGEIEQGSNRRYQVSALHTSKACNIISKYTAFVPVDVSKSRYLPT
                     VVEYPNSGAALRMLGSRALAQQWRGTSSGFGRPQTMLGEDSAPGNDMEASPTALFSEA
                     RSPGREKHGASEGPQRSLATNTLSSMKASENLFGSWLNLNKSRLLTRAAKGFLSKPLI
                     KAVESTSGNQSFDYIPLVSLQLASGAFLLNEAFCEATHIPMEKLKWTSPFTCHRVSLT
                     TRPSESKTPSPQLCTSSPPRHPSCDSFSLEPLAKGKLGLEPRAVVEHTGKLWATVVGL
                     AWLEHSSASYFTEWELVAAKANSWLEQQEVPEGRTQGTLKAAARQLFVLLRHWDENLE
                     FNMLCYNPNYV"
     exon            380..532
                     /gene="VWA5B1"
                     /inference="alignment:Splign:2.1.0"
     exon            533..803
                     /gene="VWA5B1"
                     /inference="alignment:Splign:2.1.0"
     exon            804..949
                     /gene="VWA5B1"
                     /inference="alignment:Splign:2.1.0"
     exon            950..1081
                     /gene="VWA5B1"
                     /inference="alignment:Splign:2.1.0"
     exon            1082..1206
                     /gene="VWA5B1"
                     /inference="alignment:Splign:2.1.0"
     exon            1207..1383
                     /gene="VWA5B1"
                     /inference="alignment:Splign:2.1.0"
     exon            1384..1494
                     /gene="VWA5B1"
                     /inference="alignment:Splign:2.1.0"
     exon            1495..1697
                     /gene="VWA5B1"
                     /inference="alignment:Splign:2.1.0"
     exon            1698..1812
                     /gene="VWA5B1"
                     /inference="alignment:Splign:2.1.0"
     exon            1813..1998
                     /gene="VWA5B1"
                     /inference="alignment:Splign:2.1.0"
     exon            1999..2182
                     /gene="VWA5B1"
                     /inference="alignment:Splign:2.1.0"
     exon            2183..2373
                     /gene="VWA5B1"
                     /inference="alignment:Splign:2.1.0"
     exon            2374..2551
                     /gene="VWA5B1"
                     /inference="alignment:Splign:2.1.0"
     exon            2552..2866
                     /gene="VWA5B1"
                     /inference="alignment:Splign:2.1.0"
     exon            2867..3004
                     /gene="VWA5B1"
                     /inference="alignment:Splign:2.1.0"
     exon            3005..3118
                     /gene="VWA5B1"
                     /inference="alignment:Splign:2.1.0"
     exon            3119..3193
                     /gene="VWA5B1"
                     /inference="alignment:Splign:2.1.0"
     exon            3194..3263
                     /gene="VWA5B1"
                     /inference="alignment:Splign:2.1.0"
     exon            3264..3381
                     /gene="VWA5B1"
                     /inference="alignment:Splign:2.1.0"
     exon            3382..9143
                     /gene="VWA5B1"
                     /inference="alignment:Splign:2.1.0"
     regulatory      9123..9128
                     /regulatory_class="polyA_signal_sequence"
                     /gene="VWA5B1"
                     /note="hexamer: GATAAA"
     polyA_site      9143
                     /gene="VWA5B1"
                     /note="major polyA site"
ORIGIN      
        1 gacaaaacaa atggctcggc ctcctgcagg ccacctaaac agctatcgca atgtgggcat
       61 tgatcaagcc agctgccagg gcagcgggcg cagggcttgg gcactggagc ccagccccgg
      121 accgcacctc cagcagtgct gggtgcagaa ggcagtcact gtggcagtgg agagacagag
      181 tgtgtaccca gacacgtgtt gcttctgggg taaggttctg aaggctgagt agccagcggg
      241 atgcccggct tgctgaattg gatcacgggg gcagccctgc ccctcaccgc gtctgatgtt
      301 acctcctgtg tcagcggtta tgccctgggc ctaactgcct ccctcaccta tggcaacctg
      361 gaagcccagc ccttccaggg cctcttcgtg taccccctgg atgagtgcac cacggtgatc
      421 ggctttgagg cagtcattgc cgaccgtgtc gtgacagtac agatcaagga caaagccaag
      481 ctggagagcg gccacttcga tgcctcccat gttcgatccc caacagtcac agggaacatt
      541 ctgcaagacg gggtttccat agcccctcat tcctgcacac cgggaaaggt gaccttggac
      601 gaggatttgg agcggatcct gttcgtggcc aacctgggga ccattgcccc catggagaat
      661 gtcaccatct tcatcagcac ctcctcggag ctcccaacgc tgcccagcgg ggctgtgagg
      721 gtccttctgc ctgctgtctg tgccccaacc gtgccccagt tctgcaccaa gagcactggc
      781 acctccaacc aacaggccca gggcaaagac aggcactgct tcggtgcctg ggccccgggc
      841 tcctggaata agttgtgcct ggcgactctc ctgaacaccg aagtgtccaa ccccatggag
      901 tatgagttca acttccagct ggagatccgt gggccatgtc tgctcgcagg ggtggagagt
      961 cccactcatg agattcgtgc cgacgccgcc ccatctgccc gctcggccaa gagcatcatc
     1021 atcaccttgg ccaacaagca cacctttgac cggcctgtgg agatcctcat ccaccccagc
     1081 gagccccata tgccccatgt cctgatagag aaaggggaca tgaccctggg agagtttgac
     1141 cagcacttga agggaagaac agatttcatt aaagggatga agaagaagag cagagcagag
     1201 cggaagacag aaatcattcg aaaacgcctc cacaaagaca ttccccacca ctccgtcatc
     1261 atgctcaact tctgtcccga cctccagtca gtccagccgt gcctgagaaa ggcccacggg
     1321 gagttcatct tcctcattga caggagcagc agcatgagcg ggatcagcat gcaccgagtc
     1381 aaggatgcca tgttggtggc ccttaagagc ctcatgccag cctgcctctt caatatcatt
     1441 gggtttggat ccacatttaa gagccttttt ccttccagcc agacctacag tgaggacagc
     1501 ttggccatgg cttgtgatga catccagaga atgaaggccg acatgggtgg gaccaacatc
     1561 ctttcccctc tcaagtgggt catcaggcag ccagtgcacc gaggccaccc gcggctcctc
     1621 ttcgtgatca cagatggcgc tgtcaacaac acagggaagg tgctggagct ggtgcgaaat
     1681 cacgccttct ccaccaggtg ctatagcttt ggaattggac ccaacgtctg ccacagactg
     1741 gtgaaaggac tggcatctgt gtccgagggc agtgctgagc tcctgatgga gggggagcgg
     1801 ctgcaaccca agatggtcaa atccttgaag aaggccatgg ccccagtcct gagcgatgtg
     1861 actgtggagt ggatcttccc tgagaccact gaggtcctgg tctcacccgt cagcgccagc
     1921 tccctcttcc ctggagaacg gctggtgggg tatggcattg tatgtgatgc ttctttgcac
     1981 atctccaatc ccagatctga caagaggcgc cggtacagca tgctgcactc tcaggagtct
     2041 ggcagctctg tcttctacca ctctcaggat gacggacccg ggctggaagg tggagactgt
     2101 gccaagaact cgggggcacc cttcatccta gggcaggcca aaaatgcccg gctagccagc
     2161 ggagactcta ccaccaagca cgatctgaac ctctctcagc gacggagggc atacagcacc
     2221 aaccagatca ccaatcacaa gcccctccca agagccacca tggcaagtga ccccatgcca
     2281 gctgccaaga gatacccact gcggaaagcc aggctgcagg acctcaccaa ccagaccagc
     2341 ctggatgtcc agcggtggca gattgatttg cagcccttgc tgaacagtgg tcaggacctg
     2401 aaccagggcc ccaaactccg tggcccaggg gcccgaaggc cctctctgct gccccaaggc
     2461 tgccagccct tcctgccctg gggccaggag acccaggcct ggagccctgt gagagagcgg
     2521 acttctgaca gccgaagccc tggagatctg gagccgtccc accatccctc tgccttcgag
     2581 acagagacgt cctcggactg ggacccccca gccgagtccc aggagcgagc cagtcccagc
     2641 aggcccgcca ccccggcccc ggtgctgggc aaggccctgg tcaaaggcct gcacgacagc
     2701 caacgcctgc agtgggaggt gagcttcgag ctggggaccc ctggaccgga gcggggcggc
     2761 gcgcaggatg ccgacctatg gagcgagacc ttccaccacc tggcggcccg cgccatcatc
     2821 cgcgacttcg agcagctggc ggagcgcgag ggcgagatcg agcaggggtc caaccgccgc
     2881 taccaagtga gcgccttgca caccagcaag gcctgcaaca tcattagcaa atacacagcc
     2941 ttcgtgcctg tggacgtgag caagagccgg tacctgccca ccgtggtgga gtaccccaac
     3001 tctggagctg ccctgcgtat gcttggctct cgggccctgg cccaacagtg gaggggcacc
     3061 tcttctggct ttggaaggcc gcagacgatg cttggagaag attcggcacc aggaaatgac
     3121 atggaggcaa gtcccactgc tctcttcagc gaggccaggt cccccggccg cgagaagcac
     3181 ggtgcttctg aaggtcccca gcgcagcctg gctacaaata ctctttcttc catgaaggcc
     3241 tcagagaatc tctttggatc ctggctaaat ctcaacaagt ccaggctact gacgcgagca
     3301 gccaagggct tcctgagcaa gccactgatc aaagctgtgg agtcgacctc cgggaaccag
     3361 agcttcgact acatacctct ggtgtctctg cagctggcct ccggagcctt cctgctcaac
     3421 gaagccttct gtgaggccac gcacatcccc atggagaagc tcaagtggac gtcccccttc
     3481 acctgccatc gagtgtccct caccacccgc ccgtctgagt ccaagacccc gagtccccag
     3541 ctgtgcacca gctccccgcc taggcacccg tcctgtgaca gcttctccct ggagcctctg
     3601 gccaagggca agctgggcct ggagccgagg gcagtggtgg agcacactgg gaagctgtgg
     3661 gccacggtgg tggggctggc atggctggag cacagttcgg cctcctactt cactgagtgg
     3721 gagttggtgg ctgccaaggc caactcatgg ctggagcagc aggaagtacc cgagggccgc
     3781 acgcagggca cactcaaggc cgctgcccgc cagctgtttg tgcttctgcg gcactgggat
     3841 gagaatctcg agttcaatat gctctgctat aacccgaatt atgtgtagtt gagtgacggg
     3901 gaggctgggt ggagggaagg gtggggagga gagggatggg cagggccatg tcggcctggt
     3961 ttcggggagc ttttggagct gtaactaata tttcagttac tagaaagagc cctggactgg
     4021 cagccaggag gcctgagttc aatcccaact ttgctaccat ccagccatgc aactttaggc
     4081 cagtgcctgc ccccgtctgg gcctcagttt cctcatctat aaaataagag ggcgagatga
     4141 aggaggtgga gtggatctca aatggttcag tggttccttt ctgcccattc aggcagtccc
     4201 gggctgactg ctgctggggc tggcgaggga agatgcagtg gaagcctgag ccctgtctgg
     4261 aggtagacca cgtgggcacg gagtggacac agcaatgccc actcaaataa aagggcagat
     4321 gagagaaccc agtgacctca agtaaccagg cctacaggct tgcataggca catagagact
     4381 agcaagtctg gtgcctgtag gacaggctct tgtctccatg gtaacagcca aggacccccc
     4441 ctaaatccca cttaaaagcc aattggagaa gcatccttct caacgcttta caaaagagta
     4501 gtttgggggc cttttgtttt ggctaggaag cttccttaat acatactagt attgccttgc
     4561 agatcattag tggctccctc actaagaaga ggtggtggca ggaccagggg agacaccttg
     4621 tgagttgacg tgttagattt aagcagcagt ctgtgcaaaa atagtcctaa aagaacagac
     4681 atggtcacag aagtcaatga agacaccaga caacacctta cttaattttc ccacttttag
     4741 gaattgggta aagcgaactg catcacttgt actgaggcac gagggagcca ccaccaagta
     4801 ggtcgcacca tgggatcagg gggtcctctg gagccatgcc acgctgtggg agagaggctt
     4861 ggctgcagtg cctttgggga tggcagctct ggccagggga ggcctgattt gtttggtgaa
     4921 atgaatgaat tgacacttca ggctggatcc cctaggggct tcctgccctc aagcccactg
     4981 tgtgatgcct acatggggaa tggcgtgctg tggccgcaga taccctaatg gctggcatag
     5041 agctgcccag tctcctcttc cccactgact cccctggagg tgggtctaga cctcaccaag
     5101 gaaccccacc agcttgggac ttcaggctga atctatccac cctcgaagcc ccctccttca
     5161 aggccttaat ctctcctcat caaattcctg tcccaacctt ggagtgaagc tccacagact
     5221 tccctcgtgg gaaggccttg gaagcttagc ttatcaaacc aactcgtggg gtcctgcggg
     5281 ctctggcgca agccccggcc tcaggaagac tcgaggggtg tgcagcctcc agcaggggct
     5341 ggagtcaggg aggaggctcc agcagaacgc ccactgggca caaggggaga aaaagcagcc
     5401 ccaacatgat atggtgccct gccccccacc cccacccctc catctatgcc acaagtctcc
     5461 cgcgagggat tctcacagcc cttttgaata cttaagatga aatcccattg ctgccttgtg
     5521 gactggctct gcttcagact taccctctgg ggaggaaccc aggcaggcag gcctggacac
     5581 tgtggccatc acaaccccag gtggggcagg atgccaatct ggggtgttgg ctcaaagtca
     5641 gtgccaccaa ggcgggtaag agctttgggt tgtcttgctc caggcttcca ggagatgtga
     5701 gcggagcttt gtcatctccc tgcacactcc ccatcccctg ccaaaatcac ttctttagct
     5761 atgcaggcag cagcctcagc ttcagggtaa gggtggccgg gggtggcatc tacttcctgg
     5821 accacaagta atggaaaaaa aatgccaggt tttgagtcag aacacccaga ctcaggtctc
     5881 agcctagtac tagtttgggc aagtggtttc tcctcctagg tgccctggag ctggggcttt
     5941 ctcctgctct gacagtccca gactctctgc ctctgagatg tttccctctt catgaacatg
     6001 aatttgcttg agttctctgt gtgaccttga acaagtggcg tgtgtgttct gggcctcttt
     6061 cttcctctac ataaccaggc tgaactgggc tgtccagcac ctccctgccc caccagatga
     6121 gtctgattct gggtctccag gcctcagcct ggacaatggc cagggcttga ggtgaaccgg
     6181 tctctgccag catagaacta gtgctacaag atgcctagca ggagcaacca agaaatccag
     6241 caaggtggtg ggcatgccac ccacttctct aggaaagttc ctcagactgc tcccgcaccg
     6301 gccactggag ctctgcaaca tgtttgaggc ccaagaaaac tgctgatctc tgcaaccctg
     6361 gctcccctgc ccagccccaa aggtgcagaa gaacaaatct tcattggttg caaataaccc
     6421 aagagctatg ggggcaggtc tggacaagag acatttttaa agaacttcag tggtattgag
     6481 atgacatgca gcctcaaaaa cgtgctaccg ggactgctag gcagaggacc taggggactc
     6541 gctttaagga aaagataaga acctttggta attagtacat acattgaagc taacagagtt
     6601 ctaaagtttc tcaagcaggg aacacattgc ccctgcaatc tcatttactt tgggttaatc
     6661 tggtttaact tgctaaacca gcccttgctt tctaggtcat acaaaggaat atttatgccc
     6721 tgcactgtct gaagaaaggg ctaatgccac cgtaagacaa agcccagcct ccaagctgcc
     6781 ttcagtggga aaaacactga gctgagagtt gaggaaccca agcatgggtc ccaactccac
     6841 cactagtgtg ctgtgtgact tctggcaaat tacttgcttt ctctgaaccc ctgtttcatc
     6901 ttttgtggaa tgacgggggt tcacaagatc agcatttcca accctgttcc tcacttagat
     6961 gagacgtgaa taagcaacct atgagaaact gtgctatggg caaagatgtt gaggaagcag
     7021 tagaaagaca aacttcttta gattaggaca acctgacccg ttaatatgtt actgtgcgtt
     7081 gtcaggctcc gagcaggtga cccagcagca gctcttctct ggttactagg tcgcaaaatg
     7141 ctggtctaga tctctcttag ggctcctgcg gcactggcgt tcagaaagcc tttactgggt
     7201 gcctactgta tgccaggcat ggcatactgg ggtaccacag tgaacatacg aggtgctgtc
     7261 cctgtccttt ttggagcttg gcaaggagca tttgaagagt ctctgtttca tgaatcattt
     7321 tcccactcct tggttctcta ggtgggtttg tcttcactgg ccctagaatg gtcctgccat
     7381 ctgtgggtgt ggcctcgtat tagcactacc taggtaccct ttgcgctaac ggccagcccc
     7441 ctgagctttc aggctctcat ttatggtatg ggtacagatg accacaatag ctcatggtat
     7501 tgcacagcca gaggggagtt ggtgctgggg gcctccttgt ccaggtggag caggaatgtc
     7561 cctgcaacag agtgccccga gggcccaacc tcccaccaca tgcagatgca gaaccctgtc
     7621 tcaggcccct cagctcgaga ccaactccag atgccaggat aactgggccc catcctttgg
     7681 cagacttaca ctggacttgt ccataagcgg cctcggtttc cagccggcac ccatgtttcc
     7741 ccagccagtc ccttctctgc gggcaaaatg aatggcatcc cctagccttc actgacctga
     7801 gctgccactc actgccactt gctgtggctg atgaatagac tagctgcttc caagactcga
     7861 ttctggtggg ctttcacctg ctcttcagag acatgaaaag caagggttcc tccttctccc
     7921 ttccagctgg ttcaccagga acagctgtca aaaaaggttt ctggaagttt cctctagatc
     7981 ctgacttgcc ctctgttaat ccctaccctt atttgagggc catgctactg ttccccttct
     8041 ctcttccttg gcagggactc cccatgagag ggaaggagga aagggggtct cccctatctg
     8101 tgtacagtct gcccccccac cctgcaattg cctgccccat tgacctgcct ggctggatcc
     8161 tgtgtgacac cccagcacct atcattcagg ggtccaaatg cccaaatgca catctctcta
     8221 tgtgcccatt ataacatctc taagtggtct ctagaatcaa atgcactcca tacttttagt
     8281 gccctgggaa aggagaggga agggtactgc cgccccatga atggggcatg tgctcattgc
     8341 cttggcatct ggaagatttt gttcttacca atctagcaga gactagagaa gtcaacagaa
     8401 aaaagatgga cacattcttc agctgtaaca tagcatgctc tgcaaagcca gtgtaaaaat
     8461 aaccagggca ggggtgtgtg tggcattttg cagctgggta atctgatccg cagagatctg
     8521 tccaaggtca ggggcttggc agcagctcct ggccacgcct acagctccca accgtggacc
     8581 tctctgccct gtgtgtccag ccctgctccc agcccgttga ctttagcctc tcaacagcac
     8641 tgcctccccg ggttacccga tgaggtggga tttttctcct gttcatgctg caaatctcct
     8701 tggctcaggg ccagccgttt tgagcttaca gccacgtccc aacgcaatgc gcctcatctc
     8761 aatgccgctg actgtggtga cacatgtggt atagtttcac tatctgccca ggtggctttg
     8821 gctcaagtgg catggctggt gcttgtcccc atcagagcct caagtgccta tggcatgcta
     8881 cccgtgccct tgcctgctca tctgtaatgt ccccatagtg cctatgacac tttcttcttc
     8941 ttgggatatg catcacctgc ttgcctggta gccaattaca tagatgtcat ggaagccctg
     9001 gatgtcagcc gtctaatgtc cactaatact cagcaaatcc taccatgggg ctgtgtgtgt
     9061 gtctgttctc aaagaaatgg cttctttgta catggtggct accattatct aggctttgag
     9121 ctgataaaaa ttgttgaacc tga
//
