LOCUS       XM_047431755            1732 bp    mRNA    linear   PRI 25-AUG-2024
DEFINITION  PREDICTED: Homo sapiens VRK serine/threonine kinase 1 (VRK1),
            transcript variant X4, mRNA.
ACCESSION   XM_047431755
VERSION     XM_047431755.1
DBLINK      BioProject: PRJNA168
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_000014.9) annotated using gene prediction method: Gnomon,
            supported by EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_000001405.40-RS_2024_08
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           RefSeqFE; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 08/23/2024
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1732
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="14"
     gene            1..1732
                     /gene="VRK1"
                     /gene_synonym="HMNR10; PCH1; PCH1A"
                     /note="VRK serine/threonine kinase 1; Derived by automated
                     computational analysis using gene prediction method:
                     Gnomon. Supporting evidence includes similarity to: 82
                     ESTs, 666 long SRA reads, 5 Proteins, and 100% coverage of
                     the annotated genomic feature by RNAseq alignments,
                     including 28 samples with support for all annotated
                     introns"
                     /db_xref="GeneID:7443"
                     /db_xref="HGNC:HGNC:12718"
                     /db_xref="MIM:602168"
     CDS             72..1331
                     /gene="VRK1"
                     /gene_synonym="HMNR10; PCH1; PCH1A"
                     /codon_start=1
                     /product="serine/threonine-protein kinase VRK1 isoform X3"
                     /protein_id="XP_047287711.1"
                     /db_xref="GeneID:7443"
                     /db_xref="HGNC:HGNC:12718"
                     /db_xref="MIM:602168"
                     /translation="MPRVKAAQAGRQSSAKRHLAEQFAVGEIITDMAKKEWKVGLPIG
                     QGGFGCIYLADMNSSESVGSDAPCVVKVEPSDNGPLFTELKFYQRAAKPEQIQKWIRT
                     RKLKYLGVPKYWGSGLHDKNGKSYRFMIMDRFGSDLQKIYEANAKRFSRKTVLQLSLR
                     ILDILEYIHEHEYVHGDIKASNLLLNYKNPDQVYLVDYGLAYRYCPEGVHKEYKEDPK
                     RCHDGTIEFTSIDAHNGVAPSRRGDLEILGYCMIQWLTGHLPWEDNLKDPKYVRDSKI
                     RYRENIASLMDKCFPEKNKPGEIAKYMETVKLLDYTEKPLYENLRDILLQGLKAIGSK
                     DDGKLDLSVVENGGLKAKTITKRKKEIEESKEPGVEDTEWSNTQTEEAIQTRSEESQG
                     AIHRSMSQPEASSSSYDSSRTRKRVQK"
ORIGIN      
        1 gttacgagtc ggcgaaagcg gcgggaagtt cgtactgggc agaacgcgac gggtctgcgg
       61 cttaggtgaa aatgcctcgt gtaaaagcag ctcaagctgg aagacagagc tctgcaaaga
      121 gacatcttgc agaacaattt gcagttggag agataataac tgacatggca aaaaaggaat
      181 ggaaagtagg attacccatt ggccaaggag gctttggctg tatatatctt gctgatatga
      241 attcttcaga gtcagttggc agtgatgcac cttgtgttgt aaaagtggaa cccagtgaca
      301 atggacctct ttttactgaa ttaaagttct accaacgagc tgcaaaacca gagcaaattc
      361 agaaatggat tcgtacccgt aagctgaagt acctgggtgt tcctaagtat tgggggtctg
      421 gtctacatga caaaaatgga aaaagttaca ggtttatgat aatggatcgc tttgggagtg
      481 accttcagaa aatatatgaa gcaaatgcca aaaggttttc tcggaaaact gtcttgcagc
      541 taagcttaag aattctggat attctggaat atattcacga gcatgagtat gtgcatggag
      601 atatcaaggc ctcaaatctt cttctgaact acaagaatcc tgaccaggtg tacttggtag
      661 attatggcct tgcttatcgg tactgcccag aaggagttca taaagaatac aaagaagacc
      721 ccaaaagatg tcacgatggc actattgaat tcacgagcat cgatgcacac aatggcgtgg
      781 ccccatcaag acgtggtgat ttggaaatac ttggttattg catgatccaa tggcttactg
      841 gccatcttcc ttgggaggat aatttgaaag atcctaaata tgttagagat tccaaaatta
      901 gatacagaga aaatattgca agtttgatgg acaaatgttt tcctgagaaa aacaaaccag
      961 gtgaaattgc caaatacatg gaaacagtga aattactaga ctacactgaa aaacctcttt
     1021 atgaaaattt acgtgacatt cttttgcaag gactaaaagc tataggaagt aaggatgatg
     1081 gcaaattgga cctcagtgtt gtggagaatg gaggtttgaa agcaaaaaca ataacaaagc
     1141 gaaagaaaga aattgaagaa agcaaggaac ctggtgttga agatacggaa tggtcaaaca
     1201 cacagacaga ggaggccata cagacccgaa gtgaggagtc ccaaggagca atacatcgaa
     1261 gcatgtctca gccagaggct agcagcagca gctatgacag ttcaagaacc agaaagagag
     1321 tccagaagta attcagatgc tgtgaaccag atttcctttt ctttgttttc ttttgacttt
     1381 tttctccttt tctatttgaa ctgttttatt ttcctgtgag tcttgcgagg tggaagtaat
     1441 gattaaatac tcatgtgttc agaaaacata aacttttttt ataaaaatat tttgtacaat
     1501 tcattaaagg ctaatttatg aaatttgaaa atcttcaggt tatactcctt aagttatccc
     1561 aaagccgtgt gtttgtgatg ttttggagta catatatatg aaaattatta tgacacgcac
     1621 ttttctaatc attgtacatt tctcagagtg gataaaaatg tttgacaaag tcctcacttt
     1681 taaggaaatg caaagcttaa aataaaactc tcttttgttt gatgcaaaca ca
//
