LOCUS       NM_004913               2660 bp    mRNA    linear   PRI 19-SEP-2024
DEFINITION  Homo sapiens VPS9 domain containing 1 (VPS9D1), mRNA.
ACCESSION   NM_004913
VERSION     NM_004913.3
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 2660)
  AUTHORS   Nakashima,S., Matsui,T. and Fukuda,M.
  TITLE     Vps9d1 regulates tubular endosome formation through specific
            activation of Rab22A
  JOURNAL   J Cell Sci 136 (6) (2023)
   PUBMED   36762583
  REMARK    GeneRIF: Vps9d1 regulates tubular endosome formation through
            specific activation of Rab22A.
REFERENCE   2  (bases 1 to 2660)
  AUTHORS   Cho,N.H., Cheveralls,K.C., Brunner,A.D., Kim,K., Michaelis,A.C.,
            Raghavan,P., Kobayashi,H., Savy,L., Li,J.Y., Canaj,H., Kim,J.Y.S.,
            Stewart,E.M., Gnann,C., McCarthy,F., Cabrera,J.P., Brunetti,R.M.,
            Chhun,B.B., Dingle,G., Hein,M.Y., Huang,B., Mehta,S.B.,
            Weissman,J.S., Gomez-Sjoberg,R., Itzhak,D.N., Royer,L.A., Mann,M.
            and Leonetti,M.D.
  TITLE     OpenCell: Endogenous tagging for the cartography of human cellular
            organization
  JOURNAL   Science 375 (6585), eabi6983 (2022)
   PUBMED   35271311
REFERENCE   3  (bases 1 to 2660)
  AUTHORS   Huttlin,E.L., Bruckner,R.J., Navarrete-Perea,J., Cannon,J.R.,
            Baltier,K., Gebreab,F., Gygi,M.P., Thornock,A., Zarraga,G., Tam,S.,
            Szpyt,J., Gassaway,B.M., Panov,A., Parzen,H., Fu,S., Golbazi,A.,
            Maenpaa,E., Stricker,K., Guha Thakurta,S., Zhang,T., Rad,R.,
            Pan,J., Nusinow,D.P., Paulo,J.A., Schweppe,D.K., Vaites,L.P.,
            Harper,J.W. and Gygi,S.P.
  TITLE     Dual proteome-scale networks reveal cell-specific remodeling of the
            human interactome
  JOURNAL   Cell 184 (11), 3022-3040 (2021)
   PUBMED   33961781
REFERENCE   4  (bases 1 to 2660)
  AUTHORS   Luck,K., Kim,D.K., Lambourne,L., Spirohn,K., Begg,B.E., Bian,W.,
            Brignall,R., Cafarelli,T., Campos-Laborie,F.J., Charloteaux,B.,
            Choi,D., Cote,A.G., Daley,M., Deimling,S., Desbuleux,A., Dricot,A.,
            Gebbia,M., Hardy,M.F., Kishore,N., Knapp,J.J., Kovacs,I.A.,
            Lemmens,I., Mee,M.W., Mellor,J.C., Pollis,C., Pons,C.,
            Richardson,A.D., Schlabach,S., Teeking,B., Yadav,A., Babor,M.,
            Balcha,D., Basha,O., Bowman-Colin,C., Chin,S.F., Choi,S.G.,
            Colabella,C., Coppin,G., D'Amata,C., De Ridder,D., De Rouck,S.,
            Duran-Frigola,M., Ennajdaoui,H., Goebels,F., Goehring,L., Gopal,A.,
            Haddad,G., Hatchi,E., Helmy,M., Jacob,Y., Kassa,Y., Landini,S.,
            Li,R., van Lieshout,N., MacWilliams,A., Markey,D., Paulson,J.N.,
            Rangarajan,S., Rasla,J., Rayhan,A., Rolland,T., San-Miguel,A.,
            Shen,Y., Sheykhkarimli,D., Sheynkman,G.M., Simonovsky,E., Tasan,M.,
            Tejeda,A., Tropepe,V., Twizere,J.C., Wang,Y., Weatheritt,R.J.,
            Weile,J., Xia,Y., Yang,X., Yeger-Lotem,E., Zhong,Q., Aloy,P.,
            Bader,G.D., De Las Rivas,J., Gaudet,S., Hao,T., Rak,J.,
            Tavernier,J., Hill,D.E., Vidal,M., Roth,F.P. and Calderwood,M.A.
  TITLE     A reference map of the human binary protein interactome
  JOURNAL   Nature 580 (7803), 402-408 (2020)
   PUBMED   32296183
REFERENCE   5  (bases 1 to 2660)
  AUTHORS   Choy,K.W., Wang,C.C., Ogura,A., Lau,T.K., Rogers,M.S., Ikeo,K.,
            Gojobori,T., Lam,D.S. and Pang,C.P.
  TITLE     Genomic annotation of 15,809 ESTs identified from pooled early
            gestation human eyes
  JOURNAL   Physiol Genomics 25 (1), 9-15 (2006)
   PUBMED   16368877
REFERENCE   6  (bases 1 to 2660)
  AUTHORS   Sugimoto,J., Hatakeyama,T. and Isobe,M.
  TITLE     Isolation and mapping of a putative b subunit of human ATP synthase
            (ATP-BL) from human leukocytes
  JOURNAL   DNA Res 6 (1), 29-35 (1999)
   PUBMED   10231027
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AI458261.1, BC052626.1, AB018551.1, AC010538.9, BY795348.2,
            BM920493.1 and CA428853.1.
            
            On Nov 22, 2018 this sequence version replaced NM_004913.2.
            
            ##Evidence-Data-START##
            RNAseq introns :: mixed sample support SAMEA1965299, SAMEA1966682
                              [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000389386.8/ ENSP00000374037.3
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-137               AI458261.1         89-225
            138-231             BC052626.1         607-700
            232-255             AB018551.1         361-384
            256-257             AC010538.9         24895-24896
            258-348             AB018551.1         387-477
            349-899             BY795348.2         58-608
            900-1113            AB018551.1         1029-1242
            1114-1833           BM920493.1         67-786
            1834-2202           AB018551.1         1960-2328
            2203-2645           AC010538.9         34083-34525
            2646-2660           CA428853.1         20-34               c
FEATURES             Location/Qualifiers
     source          1..2660
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="16"
                     /map="16q24.3"
     gene            1..2660
                     /gene="VPS9D1"
                     /gene_synonym="ATP-BL; ATPBL; C16orf7"
                     /note="VPS9 domain containing 1"
                     /db_xref="GeneID:9605"
                     /db_xref="HGNC:HGNC:13526"
                     /db_xref="MIM:619292"
     exon            1..136
                     /gene="VPS9D1"
                     /gene_synonym="ATP-BL; ATPBL; C16orf7"
                     /inference="alignment:Splign:2.1.0"
     CDS             38..1933
                     /gene="VPS9D1"
                     /gene_synonym="ATP-BL; ATPBL; C16orf7"
                     /codon_start=1
                     /product="VPS9 domain-containing protein 1"
                     /protein_id="NP_004904.2"
                     /db_xref="CCDS:CCDS42220.1"
                     /db_xref="GeneID:9605"
                     /db_xref="HGNC:HGNC:13526"
                     /db_xref="MIM:619292"
                     /translation="MAAAAGDGTVKPLQSAMKLANGAIELDTGNRPREAYTEYLRSIH
                     YISQVLLEEVETTKEAGETVPPDTSKMLKLAQQCLERAQSTAAKLGKTRLKPTMPAAA
                     PIPQPAGRHRRVYSDEGGKLSPFLPPEIFQKLQGAESQSCKKELTPLEEASLQNQKLK
                     AAYEARMARLDPSQAMQKTSLTLSLQRQMMENLVIAKAREETLQRKMEERRLRLQEAA
                     NRRFCSQVALTPEEREQRALYAAILEYEQDHDWPKHWKAKLKRNPGDLSLVTSLVSHL
                     LSLPDHPIAQLLRRLQCSVYSALYPAVSRAAAPAPGCCPPTPNPGSRRLRPSQSLHCM
                     LSPPEPSAAPRPQDSPPTPPLQPGPVGSPSPLGDTASGLPDKDSSFEDLEQFLGTSER
                     QGRGRGVQPEPQLQQLKTAVEEIHNAVDRLLSLTLLAFEGLNTAASKDRCLACIEEPF
                     FSPLWPLLLALYRSVHRAREAALSRSMELYRNAPPTAIGIPTKLLPQNPEAKGATGYP
                     YCAAAQELGLLVLESCPQKKLECIVRTLRIICVCAEDYCPTPEATPQAGPPPIAAAAI
                     GADDLLPILSFVVLRSGLPQLVSECAALEEFIHEGYLIGEEGYCLTSLQSALSYVELL
                     PRGGLAK"
     exon            137..212
                     /gene="VPS9D1"
                     /gene_synonym="ATP-BL; ATPBL; C16orf7"
                     /inference="alignment:Splign:2.1.0"
     exon            213..305
                     /gene="VPS9D1"
                     /gene_synonym="ATP-BL; ATPBL; C16orf7"
                     /inference="alignment:Splign:2.1.0"
     exon            306..468
                     /gene="VPS9D1"
                     /gene_synonym="ATP-BL; ATPBL; C16orf7"
                     /inference="alignment:Splign:2.1.0"
     exon            469..580
                     /gene="VPS9D1"
                     /gene_synonym="ATP-BL; ATPBL; C16orf7"
                     /inference="alignment:Splign:2.1.0"
     exon            581..643
                     /gene="VPS9D1"
                     /gene_synonym="ATP-BL; ATPBL; C16orf7"
                     /inference="alignment:Splign:2.1.0"
     exon            644..696
                     /gene="VPS9D1"
                     /gene_synonym="ATP-BL; ATPBL; C16orf7"
                     /inference="alignment:Splign:2.1.0"
     exon            697..784
                     /gene="VPS9D1"
                     /gene_synonym="ATP-BL; ATPBL; C16orf7"
                     /inference="alignment:Splign:2.1.0"
     exon            785..870
                     /gene="VPS9D1"
                     /gene_synonym="ATP-BL; ATPBL; C16orf7"
                     /inference="alignment:Splign:2.1.0"
     exon            871..1295
                     /gene="VPS9D1"
                     /gene_synonym="ATP-BL; ATPBL; C16orf7"
                     /inference="alignment:Splign:2.1.0"
     exon            1296..1425
                     /gene="VPS9D1"
                     /gene_synonym="ATP-BL; ATPBL; C16orf7"
                     /inference="alignment:Splign:2.1.0"
     exon            1426..1634
                     /gene="VPS9D1"
                     /gene_synonym="ATP-BL; ATPBL; C16orf7"
                     /inference="alignment:Splign:2.1.0"
     exon            1635..1734
                     /gene="VPS9D1"
                     /gene_synonym="ATP-BL; ATPBL; C16orf7"
                     /inference="alignment:Splign:2.1.0"
     exon            1735..1839
                     /gene="VPS9D1"
                     /gene_synonym="ATP-BL; ATPBL; C16orf7"
                     /inference="alignment:Splign:2.1.0"
     exon            1840..2660
                     /gene="VPS9D1"
                     /gene_synonym="ATP-BL; ATPBL; C16orf7"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2640..2645
                     /regulatory_class="polyA_signal_sequence"
                     /gene="VPS9D1"
                     /gene_synonym="ATP-BL; ATPBL; C16orf7"
                     /note="hexamer: AATAAA"
     polyA_site      2660
                     /gene="VPS9D1"
                     /gene_synonym="ATP-BL; ATPBL; C16orf7"
                     /note="major polyA site"
ORIGIN      
        1 ccctcggcta ccgccgccgc ctcccccgct cggcgccatg gccgctgcgg ccggggacgg
       61 cacggtgaag ccgctgcaga gcgccatgaa gcttgccaac ggggccatcg agctggacac
      121 cggcaaccgg ccccgggagg catacacgga atacctgagg agcatccact atatctccca
      181 ggtgttacta gaagaagtgg aaaccactaa agaagctggg gaaactgtgc cccccgacac
      241 ctccaagatg ctgaagctag cacagcagtg tctggagagg gcccagtcga cggccgccaa
      301 gcttgggaaa acacgcctga agccaaccat gcctgcagct gctcccattc cccagcctgc
      361 cggccgacac cgccgtgtat actccgatga aggaggaaag ctctctcctt ttctgccacc
      421 cgagatcttc cagaagcttc agggggcaga gtcacaaagc tgtaagaaag agctgacgcc
      481 actggaggag gcctccctgc agaatcagaa gctgaaggct gcgtatgagg cccgaatggc
      541 gcggctagac cccagccagg ccatgcagaa gacatccctg accctctctc tacagcggca
      601 gatgatggag aacctagtga ttgccaaagc ccgggaggag acactccaga gaaagatgga
      661 ggagcgccgg ctgcggctcc aggaggccgc caacaggagg ttttgcagcc aagtcgccct
      721 gaccccggag gaacgggagc agcgggccct ttacgccgcc atcctggagt acgaacagga
      781 ccatgactgg ccgaagcact ggaaggccaa gctcaagagg aatccggggg acctgtcact
      841 cgtgaccagc ctggtctcac acctgctcag cctccccgac cacccgatcg cgcagctcct
      901 gaggcggctg cagtgctccg tgtacagcgc cctgtatccc gccgtgagca gagcagccgc
      961 gccagcccca ggctgctgcc ccccgacccc caaccccgga agccgacggc tgcggccctc
     1021 gcagagcctc cattgcatgc tgtccccgcc cgagcccagc gcagccccgc ggccccagga
     1081 cagtcccccc acgcccccac tccaacccgg ccccgtgggg tctccctcac ccctggggga
     1141 caccgcatct ggattgccag acaaggacag ctcgttcgag gacctggagc agttcctggg
     1201 gacgtctgag cggcagggcc ggggccgtgg ggtacagccg gagccccagc tgcagcagct
     1261 gaagaccgcg gtggaggaga tccacaatgc cgtagacagg ctgctctcgc tgacccttct
     1321 ggccttcgaa ggcctaaaca cagctgcctc caaggaccgc tgcctggcct gcattgagga
     1381 accctttttc tccccgctgt ggcctctgct gctggccctg tacaggagcg tgcaccgagc
     1441 ccgggaggct gccctgagca ggagcatgga gctctacagg aatgcacccc ccaccgccat
     1501 tggcatcccc accaagctcc tcccccagaa ccctgaggcc aagggggcca ctggctaccc
     1561 ctactgcgcg gcggcccagg agctcggact gctggtcctg gagagctgcc cccagaagaa
     1621 gctggagtgc atagtgcgga ccctgcggat catctgtgtc tgtgcggaag actactgccc
     1681 caccccagag gccacacccc aggccgggcc cccgcccatc gctgcagctg ccattggtgc
     1741 cgatgacctg ctgcccatcc tgtccttcgt ggtgctgagg agcggcctcc ctcagctggt
     1801 gtcggagtgc gcggccctgg aggagttcat ccacgagggg tacctgatcg gagaggaggg
     1861 ctactgcctc acatcactgc agagtgccct gagctacgtg gagctgctgc cccggggagg
     1921 cctggccaag tagtacagct agagcccagg gtccctgcag ggcctggcct cgcctcccag
     1981 ggctgtctct cctacacctg gagccatggg atctactgag gaccatcctg gagcctcacg
     2041 ctgctctgca catggtgggg gcttgtccac tgtggtgtgc tctccagctc ttcaccttcc
     2101 tcacctcaca tctgaccctg gagcttgggg ttggcacctc tgccccgaca gaatggggct
     2161 gaatcagctc caggaggaac caggccctgc tctcctgtgt aggcctcaga gaggccaaga
     2221 agggaagctt tgggcttcgg tgggtgcagg ctcagcgatg aacatctggc tggggcagct
     2281 cctggggagc atcagggaag agggggccat gagccggcca gcagtggaga cggcagtcca
     2341 gtttctctcc cctctgaccc ctagaagggg agttgtagcc ccatgaacta gtttcttgtc
     2401 tgggtcagga acaagggccg gctggggcct ggggtgcagc tggtgtcagg gtatgctgtt
     2461 tgctgatggg cagggacacc cctgcagggt ctcgggctct gagcccagga cattccctgc
     2521 cccttactca ccttggctgt gggctgtgaa cattccggga ccctgggcat cttatctagg
     2581 tccgtgcagc ccaagggtca gccctcttga ctgtcacatg ctgcccccac ccagcctaaa
     2641 ataaagagct cactgctgtg
//
