LOCUS       NM_152564              14011 bp    mRNA    linear   PRI 15-OCT-2024
DEFINITION  Homo sapiens vacuolar protein sorting 13 homolog B (VPS13B),
            transcript variant 1, mRNA.
ACCESSION   NM_152564
VERSION     NM_152564.5
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 14011)
  AUTHORS   Du,Y., Fan,X., Song,C., Chang,W., Xiong,J., Deng,L. and Ji,W.K.
  TITLE     Sec23IP recruits VPS13B/COH1 to ER exit site-Golgi interface for
            tubular ERGIC formation
  JOURNAL   J Cell Biol 223 (12) (2024)
   PUBMED   39352497
  REMARK    GeneRIF: Sec23IP recruits VPS13B/COH1 to ER exit site-Golgi
            interface for tubular ERGIC formation.
REFERENCE   2  (bases 1 to 14011)
  AUTHORS   Afridi,T.U.K., Fatima,A., Satti,H.S., Akram,Z., Yousafzai,I.K.,
            Naeem,W.B., Fatima,N., Ali,A., Iqbal,Z., Khan,A., Shahzad,M.,
            Liu,C., Toft,M., Zhang,F., Tariq,M., Davis,E.E. and Khan,T.N.
  TITLE     Exome sequencing in four families with neurodevelopmental
            disorders: genotype-phenotype correlation and identification of
            novel disease-causing variants in VPS13B and RELN
  JOURNAL   Mol Genet Genomics 299 (1), 55 (2024)
   PUBMED   38771357
  REMARK    GeneRIF: Exome sequencing in four families with neurodevelopmental
            disorders: genotype-phenotype correlation and identification of
            novel disease-causing variants in VPS13B and RELN.
            Publication Status: Online-Only
REFERENCE   3  (bases 1 to 14011)
  AUTHORS   Hussain,A., Acharya,A., Bharadwaj,T., Genomics,U.O.W.C.F.M.,
            Leal,S.M., Khaliq,A., Mir,A. and Schrauwen,I.
  TITLE     A Novel Variant in VPS13B Underlying Cohen Syndrome
  JOURNAL   Biomed Res Int 2023, 9993801 (2023)
   PUBMED   37090188
  REMARK    GeneRIF: A Novel Variant in VPS13B Underlying Cohen Syndrome.
            Publication Status: Online-Only
REFERENCE   4  (bases 1 to 14011)
  AUTHORS   Zorn,M., Kuhnisch,J., Bachmann,S. and Seifert,W.
  TITLE     Disease relevance of rare VPS13B missense variants for
            neurodevelopmental Cohen syndrome
  JOURNAL   Sci Rep 12 (1), 9686 (2022)
   PUBMED   35690661
  REMARK    GeneRIF: Disease relevance of rare VPS13B missense variants for
            neurodevelopmental Cohen syndrome.
            Publication Status: Online-Only
REFERENCE   5  (bases 1 to 14011)
  AUTHORS   Karimzadeh,M.R., Omidi,F., Sahebalzamani,A. and Saeidi,K.
  TITLE     A Novel VPS13B Mutation Identified by Whole-Exome Sequencing in
            Iranian Patients with Cohen Syndrome
  JOURNAL   J Mol Neurosci 71 (12), 2566-2574 (2021)
   PUBMED   34041686
  REMARK    GeneRIF: A Novel VPS13B Mutation Identified by Whole-Exome
            Sequencing in Iranian Patients with Cohen Syndrome.
REFERENCE   6  (bases 1 to 14011)
  AUTHORS   Kolehmainen,J., Wilkinson,R., Lehesjoki,A.E., Chandler,K.,
            Kivitie-Kallio,S., Clayton-Smith,J., Traskelin,A.L., Waris,L.,
            Saarinen,A., Khan,J., Gross-Tsur,V., Traboulsi,E.I., Warburg,M.,
            Fryns,J.P., Norio,R., Black,G.C. and Manson,F.D.
  TITLE     Delineation of Cohen syndrome following a large-scale
            genotype-phenotype screen
  JOURNAL   Am J Hum Genet 75 (1), 122-127 (2004)
   PUBMED   15141358
  REMARK    GeneRIF: COH1 mutations is associated with Cohen syndrome
REFERENCE   7  (bases 1 to 14011)
  AUTHORS   Kolehmainen,J., Black,G.C., Saarinen,A., Chandler,K.,
            Clayton-Smith,J., Traskelin,A.L., Perveen,R., Kivitie-Kallio,S.,
            Norio,R., Warburg,M., Fryns,J.P., de la Chapelle,A. and
            Lehesjoki,A.E.
  TITLE     Cohen syndrome is caused by mutations in a novel gene, COH1,
            encoding a transmembrane protein with a presumed role in
            vesicle-mediated sorting and intracellular protein transport
  JOURNAL   Am J Hum Genet 72 (6), 1359-1369 (2003)
   PUBMED   12730828
  REMARK    GeneRIF: A mutated gene on chromosome 8q22 found by haplotype
            analysis in patients with this syndrome.
REFERENCE   8  (bases 1 to 14011)
  AUTHORS   Kolehmainen,J., Norio,R., Kivitie-Kallio,S., Tahvanainen,E., de la
            Chapelle,A. and Lehesjoki,A.E.
  TITLE     Refined mapping of the Cohen syndrome gene by linkage
            disequilibrium
  JOURNAL   Eur J Hum Genet 5 (4), 206-213 (1997)
   PUBMED   9359041
REFERENCE   9  (bases 1 to 14011)
  AUTHORS   Tahvanainen,E., Norio,R., Karila,E., Ranta,S., Weissenbach,J.,
            Sistonen,P. and de la Chapelle,A.
  TITLE     Cohen syndrome gene assigned to the long arm of chromosome 8 by
            linkage analysis
  JOURNAL   Nat Genet 7 (2), 201-204 (1994)
   PUBMED   7920642
REFERENCE   10 (bases 1 to 14011)
  AUTHORS   Wang,H., Falk,M.J., Wensel,C. and Traboulsi,E.I.
  TITLE     Cohen Syndrome
  JOURNAL   (in) Adam MP, Feldman J, Mirzaa GM, Pagon RA, Wallace SE and
            Amemiya A (Eds.);
            GENEREVIEWS(R);
            (1993)
   PUBMED   20301655
COMMENT     REVIEWED REFSEQ: This record has been curated by NCBI staff. The
            reference sequence was derived from AY223815.1, AC105195.5,
            AC023933.9 and AC105328.13.
            
            On May 21, 2020 this sequence version replaced NM_152564.4.
            
            Summary: This gene encodes a potential transmembrane protein that
            may function in vesicle-mediated transport and sorting of proteins
            within the cell. This protein may play a role in the development
            and the function of the eye, hematological system, and central
            nervous system. Mutations in this gene have been associated with
            Cohen syndrome. Multiple splice variants encoding distinct isoforms
            have been identified for this gene. [provided by RefSeq, Jul 2008].
            
            Transcript Variant: This variant (1) lacks one alternate in-frame
            exon and includes a different in-frame exon, compared to variant 5.
            The resulting isoform (1) is shorter and varies within this region
            of the protein, but has the same C- and N-termini, compared to
            isoform 5.
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AJ608773.1, AY223815.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA1965299, SAMEA1968189
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000357162.7/ ENSP00000349685.2
            RefSeq Select criteria :: based on manual assertion, conservation,
                                      expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-1659              AY223815.1         9-1667
            1660-1660           AC105195.5         119108-119108
            1661-1732           AY223815.1         1669-1740
            1733-1733           AC105195.5         120112-120112
            1734-1954           AY223815.1         1742-1962
            1955-1955           AC105195.5         131230-131230
            1956-5045           AY223815.1         1964-5053
            5046-5046           AC023933.9         83192-83192
            5047-9594           AY223815.1         5055-9602
            9595-9595           AC105328.13        112032-112032       c
            9596-14010          AY223815.1         9604-14018
            14011-14011         AC105328.13        66982-66982         c
FEATURES             Location/Qualifiers
     source          1..14011
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="8"
                     /map="8q22.2"
     gene            1..14011
                     /gene="VPS13B"
                     /gene_synonym="BLTP5B; CHS1; COH1"
                     /note="vacuolar protein sorting 13 homolog B"
                     /db_xref="GeneID:157680"
                     /db_xref="HGNC:HGNC:2183"
                     /db_xref="MIM:607817"
     exon            1..74
                     /gene="VPS13B"
                     /gene_synonym="BLTP5B; CHS1; COH1"
                     /inference="alignment:Splign:2.1.0"
     exon            75..250
                     /gene="VPS13B"
                     /gene_synonym="BLTP5B; CHS1; COH1"
                     /inference="alignment:Splign:2.1.0"
     CDS             104..12097
                     /gene="VPS13B"
                     /gene_synonym="BLTP5B; CHS1; COH1"
                     /note="isoform 1 is encoded by transcript variant 1;
                     vacuolar protein sorting-associated protein 13B;
                     intermembrane lipid transfer protein VPS13B; bridge-like
                     lipid transfer protein family member 5B"
                     /codon_start=1
                     /product="intermembrane lipid transfer protein VPS13B
                     isoform 1"
                     /protein_id="NP_689777.3"
                     /db_xref="CCDS:CCDS6281.1"
                     /db_xref="GeneID:157680"
                     /db_xref="HGNC:HGNC:2183"
                     /db_xref="MIM:607817"
                     /translation="MLESYVTPILMSYVNRYIKNLKPSDLQLSLWGGDVVLSKLELKL
                     DVLEQELKLPFTFLSGHIHELRIHVPWTKLGSEPVVITINTMECILKLKDGIQDDHES
                     CGSNSTNRSTAESTKSSIKPRRMQQAAPTDPDLPPGYVQSLIRRVVNNVNIVINNLIL
                     KYVEDDIVLSVNITSAECYTVGELWDRAFMDISATDLVLRKVINFSDCTVCLDKRNAS
                     GKIEFYQDPLLYKCSFRTRLHFTYENLNSKMPSVIKIHTLVESLKLSITDQQLPMFIR
                     IMQLGIALYYGEIGNFKEGEIEDLTCHNKDMLGNITGSEDETRIDMQYPAQHKGQELY
                     SQQDEEQPQGWVSWAWSFVPAIVSYDDGEEDFVGNDPASTMHQQKAQTLKDPIVSIGF
                     YCTKATVTFKLTEMQVESSYYSPQKVKSKEVLCWEQEGTTVEALMMGEPFFDCQIGFV
                     GCRAMCLKGIMGVKDFEENMNRSETEACFFICGDNLSTKGFTYLTNSLFDYRSPENNG
                     TRAEFILDSTHHKETYTEIAGMQRFGAFYMDYLYTMENTSGKGSTNQQDFSSGKSEDL
                     GTVQEKSTKSLVIGPLDFRLDSSAVHRILKMIVCALEHEYEPYSRLKSDIKDENETIL
                     NPEEVALLEEYIPTRHTSVTLLKCTCTISMAEFNLLDHLLPVIMGEKNSSNFMNTTNF
                     QSLRPLPSIRILVDKINLEHSVPMYAEQLVHVVSSLTQPSDNLLHYCYVHCYLKIFGF
                     QAGLTSLDCSGSYCLPVPVIPSFSTALYGKLLKLPTCWTKRSQIAITEGIFELPNLTI
                     QATRAQTLLLQAIYQSWSHLGNVSSSAVIEALINEIFLSIGVKSKNPLPTLEGSIQNV
                     ELKYCSTSLVKCASGTMGSIKICAKAPVDSGKEKLIPLLQGPSDTKDLHSTKWLNESR
                     KPESLLAPDLMAFTIQVPQYIDYCHNSGAVLLCSIQGLAVNIDPILYTWLIYQPQKRT
                     SRHMQQQPVVAVPLVMPVCRRKEDEVSIGSAPLAKQQSYQASEYASSPVKTKTVTESR
                     PLSVPVKAMLNISESCRSPEERMKEFIGIVWNAVKHLTLQLEVQSCCVFIPNDSLPSP
                     STIVSGDIPGTVRSWYHGQTSMPGTLVLCLPQIKIISAGHKYMEPLQEIPFVIPRPIL
                     EEGDAFPWTISLHNFSIYTLLGKQVTLCLVEPMGCTSTLAVTSQKLLATGPDTRHSFV
                     VCLHVDLESLEIKCSNPQVQLFYELTDIMNKVWNKIQKRGNLNLSPTSPETMAGPVPT
                     SPVRSSIGTAPPDTSTCSPSADIGTTTEGDSIQAGEESPFSDSVTLEQTTSNIGGTSG
                     RVSLWMQWVLPKITIKLFAPDPENKGTEVCMVSELEDLSASIDVQDVYTKVKCKIESF
                     NIDHYRSRPGEGWQSGHFEGVFLQCKEKSVTTTKLLDGTHQQHGFLSLTYTKAVTKNV
                     RHKLTSRNERRSFHKLSEGLMDGSPHFLHEILLSAQAFDIVLYFPLLNAIASIFQAKL
                     PKTQKEKRKSPGQPMRTHTLTSRNLPLIYVNTSVIRIFIPKTEEMQPTVEANQAAKED
                     TVVLKIGSVAMAPQADNPLGRSVLRKDIYQRALNLGILRDPGSEIEDRQYQIDLQSIN
                     IGTAQWHQLKPEKESVSGGVVTETERNSQNPALEWNMASSIRRHQERRAILTPVLTDF
                     SVRITGAPAVIFTKVVSPENLHTEEILVCGHSLEVNITTNLDFFLSVAQVQLLHQLIV
                     ANMTGLEPSNKAAEISKQEQKKVDIFDGGMAETSSRYSGAQDSGIGSDSVKIRIVQIE
                     QHSGASQHRIARPSRQSSIVKNLNFIPFDIFITASRISLMTYSCMALSKSKSQEQKNN
                     EKTDKSSLNLPEVDSDVAKPNQACISTVTAEDLLRSSISFPSGKKIGVLSLESLHAST
                     RSSARQALGITIVRQPGRRGTGDLQLEPFLYFIVSQPSLLLSCHHRKQRVEVSIFDAV
                     LKGVASDYKCIDPGKTLPEALDYCTVWLQTVPGEIDSKSGIPPSFITLQIKDFLNGPA
                     DVNLDISKPLKANLSFTKLDQINLFLKKIKNAHSLAHSEETSAMSNTMVNKDDLPVSK
                     YYRGKLSKPKIHGDGVQKISAQENMWRAVSCFQKISVQTTQIVISMETVPHTSKPCLL
                     ASLSNLNGSLSVKATQKVPGIILGSSFLLSINDFLLKTSLKERSRILIGPCCATANLE
                     AKWCKHSGNPGPEQSIPKISIDLRGGLLQVFWGQEHLNCLVLLHELLNGYLNEEGNFE
                     VQVSEPVPQMSSPVEKNQTFKSEQSSDDLRTGLFQYVQDAESLKLPGVYEVLFYNETE
                     DCPGMMLWRYPEPRVLTLVRITPVPFNTTEDPDISTADLGDVLQVPCSLEYWDELQKV
                     FVAFREFNLSESKVCELQLPDINLVNDQKKLVSSDLWRIVLNSSQNGADDQSSASESG
                     SQSTCDPLVTPTALAACTRVDSCFTPWFVPSLCVSFQFAHLEFHLCHHLDQLGTAAPQ
                     YLQPFVSDRNMPSELEYMIVSFREPHMYLRQWNNGSVCQEIQFLAQADCKLLECRNVT
                     MQSVVKPFSIFGQMAVSSDVVEKLLDCTVIVDSVFVNLGQHVVHSLNTAIQAWQQNKC
                     PEVEELVFSHFVICNDTQETLRFGQVDTDENILLASLHSHQYSWRSHKSPQLLHICIE
                     GWGNWRWSEPFSVDHAGTFIRTIQYRGRTASLIIKVQQLNGVQKQIIICGRQIICSYL
                     SQSIELKVVQHYIGQDGQAVVREHFDCLTAKQKLPSYILENNELTELCVKAKGDEDWS
                     RDVCLESKAPEYSIVIQVPSSNSSIIYVWCTVLTLEPNSQVQQRMIVFSPLFIMRSHL
                     PDPIIIHLEKRSLGLSETQIIPGKGQEKPLQNIEPDLVHHLTFQAREEYDPSDCAVPI
                     STSLIKQIATKVHPGGTVNQILDEFYGPEKSLQPIWPYNKKDSDRNEQLSQWDSPMRV
                     KLSIWKPYVRTLLIELLPWALLINESKWDLWLFEGEKIVLQVPAGKIIIPPNFQEAFQ
                     IGIYWANTNTVHKSVAIKLVHNLTSPKWKDGGNGEVVTLDEEAFVDTEIRLGAFPGHQ
                     KLCQFCISSMVQQGIQIIQIEDKTTIINNTPYQIFYKPQLSVCNPHSGKEYFRVPDSA
                     TFSICPGGEQPAMKSSSLPCWDLMPDISQSVLDASLLQKQIMLGFSPAPGADSSQCWS
                     LPAIVRPEFPRQSVAVPLGNFRENGFCTRAIVLTYQEHLGVTYLTLSEDPSPRVIIHN
                     RCPVKMLIKENIKDIPKFEVYCKKIPSECSIHHELYHQISSYPDCKTKDLLPSLLLRV
                     EPLDEVTTEWSDAIDINSQGTQVVFLTGFGYVYVDVVHQCGTVFITVAPEGKAGPILT
                     NTNRAPEKIVTFKMFITQLSLAVFDDLTHHKASAELLRLTLDNIFLCVAPGAGPLPGE
                     EPVAALFELYCVEICCGDLQLDNQLYNKSNFHFAVLVCQGEKAEPIQCSKMQSLLISN
                     KELEEYKEKCFIKLCITLNEGKSILCDINEFSFELKPARLYVEDTFVYYIKTLFDTYL
                     PNSRLAGHSTHLSGGKQVLPMQVTQHARALVNPVKLRKLVIQPVNLLVSIHASLKLYI
                     ASDHTPLSFSVFERGPIFTTARQLVHALAMHYAAGALFRAGWVVGSLDILGSPASLVR
                     SIGNGVADFFRLPYEGLTRGPGAFVSGVSRGTTSFVKHISKGTLTSITNLATSLARNM
                     DRLSLDEEHYNRQEEWRRQLPESLGEGLRQGLSRLGISLLGAIAGIVDQPMQNFQKTS
                     EAQASAGHKAKGVISGVGKGIMGVFTKPIGGAAELVSQTGYGILHGAGLSQLPKQRHQ
                     PSDLHADQAPNSHVKYVWKMLQSLGRPEVHMALDVVLVRGSGQEHEGCLLLTSEVLFV
                     VSVSEDTQQQAFPVTEIDCAQDSKQNNLLTVQLKQPRVACDVEVDGVRERLSEQQYNR
                     LVDYITKTSCHLAPSCSSMQIPCPVVAAEPPPSTVKTYHYLVDPHFAQVFLSKFTMVK
                     NKALRKGFP"
     exon            251..394
                     /gene="VPS13B"
                     /gene_synonym="BLTP5B; CHS1; COH1"
                     /inference="alignment:Splign:2.1.0"
     exon            395..515
                     /gene="VPS13B"
                     /gene_synonym="BLTP5B; CHS1; COH1"
                     /inference="alignment:Splign:2.1.0"
     exon            516..683
                     /gene="VPS13B"
                     /gene_synonym="BLTP5B; CHS1; COH1"
                     /inference="alignment:Splign:2.1.0"
     exon            684..865
                     /gene="VPS13B"
                     /gene_synonym="BLTP5B; CHS1; COH1"
                     /inference="alignment:Splign:2.1.0"
     exon            866..1040
                     /gene="VPS13B"
                     /gene_synonym="BLTP5B; CHS1; COH1"
                     /inference="alignment:Splign:2.1.0"
     exon            1041..1309
                     /gene="VPS13B"
                     /gene_synonym="BLTP5B; CHS1; COH1"
                     /inference="alignment:Splign:2.1.0"
     exon            1310..1405
                     /gene="VPS13B"
                     /gene_synonym="BLTP5B; CHS1; COH1"
                     /inference="alignment:Splign:2.1.0"
     exon            1406..1528
                     /gene="VPS13B"
                     /gene_synonym="BLTP5B; CHS1; COH1"
                     /inference="alignment:Splign:2.1.0"
     exon            1529..1666
                     /gene="VPS13B"
                     /gene_synonym="BLTP5B; CHS1; COH1"
                     /inference="alignment:Splign:2.1.0"
     exon            1667..1754
                     /gene="VPS13B"
                     /gene_synonym="BLTP5B; CHS1; COH1"
                     /inference="alignment:Splign:2.1.0"
     exon            1755..1946
                     /gene="VPS13B"
                     /gene_synonym="BLTP5B; CHS1; COH1"
                     /inference="alignment:Splign:2.1.0"
     exon            1947..2116
                     /gene="VPS13B"
                     /gene_synonym="BLTP5B; CHS1; COH1"
                     /inference="alignment:Splign:2.1.0"
     exon            2117..2311
                     /gene="VPS13B"
                     /gene_synonym="BLTP5B; CHS1; COH1"
                     /inference="alignment:Splign:2.1.0"
     exon            2312..2436
                     /gene="VPS13B"
                     /gene_synonym="BLTP5B; CHS1; COH1"
                     /inference="alignment:Splign:2.1.0"
     exon            2437..2618
                     /gene="VPS13B"
                     /gene_synonym="BLTP5B; CHS1; COH1"
                     /inference="alignment:Splign:2.1.0"
     exon            2619..2753
                     /gene="VPS13B"
                     /gene_synonym="BLTP5B; CHS1; COH1"
                     /inference="alignment:Splign:2.1.0"
     exon            2754..2927
                     /gene="VPS13B"
                     /gene_synonym="BLTP5B; CHS1; COH1"
                     /inference="alignment:Splign:2.1.0"
     exon            2928..3037
                     /gene="VPS13B"
                     /gene_synonym="BLTP5B; CHS1; COH1"
                     /inference="alignment:Splign:2.1.0"
     exon            3038..3185
                     /gene="VPS13B"
                     /gene_synonym="BLTP5B; CHS1; COH1"
                     /inference="alignment:Splign:2.1.0"
     exon            3186..3313
                     /gene="VPS13B"
                     /gene_synonym="BLTP5B; CHS1; COH1"
                     /inference="alignment:Splign:2.1.0"
     exon            3314..3548
                     /gene="VPS13B"
                     /gene_synonym="BLTP5B; CHS1; COH1"
                     /inference="alignment:Splign:2.1.0"
     exon            3549..3769
                     /gene="VPS13B"
                     /gene_synonym="BLTP5B; CHS1; COH1"
                     /inference="alignment:Splign:2.1.0"
     exon            3770..3973
                     /gene="VPS13B"
                     /gene_synonym="BLTP5B; CHS1; COH1"
                     /inference="alignment:Splign:2.1.0"
     exon            3974..4145
                     /gene="VPS13B"
                     /gene_synonym="BLTP5B; CHS1; COH1"
                     /inference="alignment:Splign:2.1.0"
     exon            4146..4260
                     /gene="VPS13B"
                     /gene_synonym="BLTP5B; CHS1; COH1"
                     /inference="alignment:Splign:2.1.0"
     exon            4261..4327
                     /gene="VPS13B"
                     /gene_synonym="BLTP5B; CHS1; COH1"
                     /inference="alignment:Splign:2.1.0"
     exon            4328..4736
                     /gene="VPS13B"
                     /gene_synonym="BLTP5B; CHS1; COH1"
                     /inference="alignment:Splign:2.1.0"
     exon            4737..4848
                     /gene="VPS13B"
                     /gene_synonym="BLTP5B; CHS1; COH1"
                     /inference="alignment:Splign:2.1.0"
     exon            4849..5052
                     /gene="VPS13B"
                     /gene_synonym="BLTP5B; CHS1; COH1"
                     /inference="alignment:Splign:2.1.0"
     exon            5053..5179
                     /gene="VPS13B"
                     /gene_synonym="BLTP5B; CHS1; COH1"
                     /inference="alignment:Splign:2.1.0"
     exon            5180..5323
                     /gene="VPS13B"
                     /gene_synonym="BLTP5B; CHS1; COH1"
                     /inference="alignment:Splign:2.1.0"
     exon            5324..6011
                     /gene="VPS13B"
                     /gene_synonym="BLTP5B; CHS1; COH1"
                     /inference="alignment:Splign:2.1.0"
     exon            6012..6149
                     /gene="VPS13B"
                     /gene_synonym="BLTP5B; CHS1; COH1"
                     /inference="alignment:Splign:2.1.0"
     exon            6150..6557
                     /gene="VPS13B"
                     /gene_synonym="BLTP5B; CHS1; COH1"
                     /inference="alignment:Splign:2.1.0"
     exon            6558..6760
                     /gene="VPS13B"
                     /gene_synonym="BLTP5B; CHS1; COH1"
                     /inference="alignment:Splign:2.1.0"
     exon            6761..6968
                     /gene="VPS13B"
                     /gene_synonym="BLTP5B; CHS1; COH1"
                     /inference="alignment:Splign:2.1.0"
     exon            6969..7153
                     /gene="VPS13B"
                     /gene_synonym="BLTP5B; CHS1; COH1"
                     /inference="alignment:Splign:2.1.0"
     exon            7154..7350
                     /gene="VPS13B"
                     /gene_synonym="BLTP5B; CHS1; COH1"
                     /inference="alignment:Splign:2.1.0"
     exon            7351..7532
                     /gene="VPS13B"
                     /gene_synonym="BLTP5B; CHS1; COH1"
                     /inference="alignment:Splign:2.1.0"
     exon            7533..7882
                     /gene="VPS13B"
                     /gene_synonym="BLTP5B; CHS1; COH1"
                     /inference="alignment:Splign:2.1.0"
     exon            7883..8044
                     /gene="VPS13B"
                     /gene_synonym="BLTP5B; CHS1; COH1"
                     /inference="alignment:Splign:2.1.0"
     exon            8045..8200
                     /gene="VPS13B"
                     /gene_synonym="BLTP5B; CHS1; COH1"
                     /inference="alignment:Splign:2.1.0"
     exon            8201..8464
                     /gene="VPS13B"
                     /gene_synonym="BLTP5B; CHS1; COH1"
                     /inference="alignment:Splign:2.1.0"
     exon            8465..8548
                     /gene="VPS13B"
                     /gene_synonym="BLTP5B; CHS1; COH1"
                     /inference="alignment:Splign:2.1.0"
     exon            8549..8724
                     /gene="VPS13B"
                     /gene_synonym="BLTP5B; CHS1; COH1"
                     /inference="alignment:Splign:2.1.0"
     exon            8725..8895
                     /gene="VPS13B"
                     /gene_synonym="BLTP5B; CHS1; COH1"
                     /inference="alignment:Splign:2.1.0"
     exon            8896..9097
                     /gene="VPS13B"
                     /gene_synonym="BLTP5B; CHS1; COH1"
                     /inference="alignment:Splign:2.1.0"
     exon            9098..9286
                     /gene="VPS13B"
                     /gene_synonym="BLTP5B; CHS1; COH1"
                     /inference="alignment:Splign:2.1.0"
     exon            9287..9433
                     /gene="VPS13B"
                     /gene_synonym="BLTP5B; CHS1; COH1"
                     /inference="alignment:Splign:2.1.0"
     exon            9434..9717
                     /gene="VPS13B"
                     /gene_synonym="BLTP5B; CHS1; COH1"
                     /inference="alignment:Splign:2.1.0"
     exon            9718..9845
                     /gene="VPS13B"
                     /gene_synonym="BLTP5B; CHS1; COH1"
                     /inference="alignment:Splign:2.1.0"
     exon            9846..10045
                     /gene="VPS13B"
                     /gene_synonym="BLTP5B; CHS1; COH1"
                     /inference="alignment:Splign:2.1.0"
     exon            10046..10164
                     /gene="VPS13B"
                     /gene_synonym="BLTP5B; CHS1; COH1"
                     /inference="alignment:Splign:2.1.0"
     exon            10165..10970
                     /gene="VPS13B"
                     /gene_synonym="BLTP5B; CHS1; COH1"
                     /inference="alignment:Splign:2.1.0"
     exon            10971..11147
                     /gene="VPS13B"
                     /gene_synonym="BLTP5B; CHS1; COH1"
                     /inference="alignment:Splign:2.1.0"
     exon            11148..11318
                     /gene="VPS13B"
                     /gene_synonym="BLTP5B; CHS1; COH1"
                     /inference="alignment:Splign:2.1.0"
     exon            11319..11495
                     /gene="VPS13B"
                     /gene_synonym="BLTP5B; CHS1; COH1"
                     /inference="alignment:Splign:2.1.0"
     exon            11496..11598
                     /gene="VPS13B"
                     /gene_synonym="BLTP5B; CHS1; COH1"
                     /inference="alignment:Splign:2.1.0"
     exon            11599..11848
                     /gene="VPS13B"
                     /gene_synonym="BLTP5B; CHS1; COH1"
                     /inference="alignment:Splign:2.1.0"
     exon            11849..14011
                     /gene="VPS13B"
                     /gene_synonym="BLTP5B; CHS1; COH1"
                     /inference="alignment:Splign:2.1.0"
     regulatory      13990..13995
                     /regulatory_class="polyA_signal_sequence"
                     /gene="VPS13B"
                     /gene_synonym="BLTP5B; CHS1; COH1"
                     /note="hexamer: AATAAA"
     polyA_site      14011
                     /gene="VPS13B"
                     /gene_synonym="BLTP5B; CHS1; COH1"
                     /note="major polyA site"
ORIGIN      
        1 acaggagcag cactgccggc gggggcgggt gccagggact tggaggtgga ggggacgcgg
       61 cggtactctg gcgtcttccg acttcgactc cttaccttaa aagatgctgg agtcatatgt
      121 aactccaatt ttaatgagct atgtgaatcg ctacatcaag aacttaaagc cgtcggatct
      181 acagctttca ctatggggtg gagacgtggt actcagcaag ctcgagttaa agttggatgt
      241 gctggaacag gaactgaaat taccattcac ttttttaagt ggacatattc atgaattgag
      301 gattcatgta ccatggacaa aactgggttc agaaccagtg gtaattacca tcaatactat
      361 ggaatgcatt ttgaaactta aggatgggat acaggatgac catgaaagct gtggttctaa
      421 ttctaccaac cgtagtactg ctgagagcac aaaatcatca atcaaaccgc ggagaatgca
      481 gcaggctgct cctacagatc ctgacttacc accaggttat gtgcagagtc tgattagacg
      541 agttgtaaat aatgtaaaca ttgtgataaa taatctcata ctaaaatatg ttgaagatga
      601 tatcgtcctt tccgtcaata tcacttctgc agaatgttat acagtaggtg aattatggga
      661 tcgtgcattc atggatattt ctgcaactga tttggtgctg agaaaggtta tcaatttttc
      721 tgactgtaca gtttgtcttg ataaacggaa tgccagtggt aaaatagaat tttaccagga
      781 tcctttatta tacaaatgtt ccttcagaac tcgtcttcat tttacatatg aaaacctaaa
      841 ttccaagatg ccatctgtta ttaaaattca tactttagtg gaaagtttga aactttctat
      901 cacagatcaa caactgccta tgtttattcg tataatgcaa cttggaattg ctctttacta
      961 tggagaaata ggcaatttta aagaaggcga aatagaggac cttacttgtc ataataaaga
     1021 tatgctagga aacattacag gttctgaaga tgaaacaaga atagatatgc aatatcctgc
     1081 tcagcataaa ggtcaagagt tatattcaca gcaagatgag gagcagccac agggatgggt
     1141 gtcatgggcc tggtcctttg tgcctgcaat tgtgagttat gacgatggcg aggaagactt
     1201 tgttgggaac gatcctgcat caaccatgca tcaacaaaaa gcacagactt tgaaggatcc
     1261 tattgtttct ataggatttt attgcacaaa ggcaacggtg actttcaaac tcacagaaat
     1321 gcaagttgag agtagttatt acagtccaca gaaagtaaaa tctaaagaag tattgtgttg
     1381 ggaacaagaa ggaactacag ttgaggccct tatgatggga gaacctttct ttgattgcca
     1441 gattgggttt gttggttgca gagccatgtg ccttaaagga attatgggtg ttaaagattt
     1501 tgaagagaat atgaatagaa gtgaaactga agcctgtttc ttcatttgtg gtgacaattt
     1561 gagtacgaaa ggtttcacat accttacaaa ttcattgttt gattaccgaa gcccagaaaa
     1621 taatggtact cgcgcagaat ttatcttgga ttcaactcat cataaggaga catacactga
     1681 gatagctgga atgcaacggt ttggggcttt ttatatggat tacctgtata caatggagaa
     1741 cactagtggc aaaggttcca caaatcaaca agacttttct tcagggaaaa gtgaagattt
     1801 gggaacagtt caggagaagt ccaccaaaag ccttgttata ggtcctcttg attttcgttt
     1861 ggatagcagt gcggtgcata ggattttgaa aatgattgtg tgtgccttgg aacatgaata
     1921 tgaaccatat agcaggctaa aatcagatat taaggatgaa aatgaaacaa tactgaatcc
     1981 tgaagaggtg gctcttctgg aggaatatat tcctactcga catacaagtg ttactctcct
     2041 caaatgtacc tgcacaattt ccatggctga attcaacttg ctggaccatt tactacctgt
     2101 cattatggga gaaaagaact caagtaactt catgaatact acaaacttcc agtctcttcg
     2161 gcctttgcca tccattcgaa tattggtgga taaaattaat ctggaacatt cagtgccaat
     2221 gtatgctgaa cagttggtgc atgtggtcag cagccttact caaccttctg ataacctgct
     2281 tcattattgt tatgtacact gctatcttaa gatatttggt ttccaggcag gactgacgtc
     2341 tttggattgc agtggatctt actgcttacc tgtaccagtt attccctctt tcagcactgc
     2401 tctttatggg aaacttctga aactccccac atgctggacc aaaagatctc agattgctat
     2461 aactgaaggt atatttgaac ttccaaatct cacaattcaa gctacaagag cacagacact
     2521 tctcttgcaa gcaatatatc aaagttggtc tcatcttgga aatgtcagct cttccgcagt
     2581 gattgaagct ttgataaatg aaatcttcct aagtataggt gtgaaatcta agaatcccct
     2641 gccaactctt gagggctcaa tccagaatgt tgaattgaag tactgcagca catcattggt
     2701 caaatgtgcc tctgggacca tgggatcaat aaaaatttgt gccaaagccc cagttgatag
     2761 tggaaaagag aagttgattc ccttgcttca gggtccttct gacactaaag accttcatag
     2821 caccaagtgg ctcaatgaga gtagaaagcc agagtctctc ttagctccag atttgatggc
     2881 cttcacaatc caagttccac aatatattga ctactgccac aattccggtg ctgtacttct
     2941 ttgcagtata caaggactag cagttaatat tgacccaatc ttatatacgt ggctcatcta
     3001 tcagcctcag aaacgaacaa gtagacatat gcaacagcag cctgtggtag ctgttcctct
     3061 tgttatgcca gtttgtagaa ggaaagagga tgaggtgtct attggaagtg cccccttggc
     3121 aaagcagcaa tcatatcagg cctctgaata tgccagcagc cctgtaaaaa caaaaacggt
     3181 aacagaatcc cgcccattgt cagttcctgt taaagccatg ttgaatatat ctgaaagctg
     3241 tagaagtcct gaagaaagaa tgaaggaatt tattggaatt gtttggaatg cagtgaagca
     3301 tctcacacta cagcttgaag tacaatcttg ttgtgtgttt attccaaatg atagcctgcc
     3361 ttccccaagt acaattgtat ctggtgacat tcctggaaca gtaagaagtt ggtaccatgg
     3421 acaaaccagc atgccgggaa cacttgtcct ctgtttgcct caaataaaga ttattagtgc
     3481 tgggcacaag tatatggaac ctctgcagga gattccattt gttatcccac gacccatcct
     3541 tgaagaaggt gatgcttttc cttggacgat cagcttgcat aatttcagca tatataccct
     3601 tcttggaaaa caagtgacac tttgcctagt ggaacctatg ggttgcacct ccactctagc
     3661 tgtcacgtct caaaaactgc ttgctacggg acctgataca cgacattcat ttgttgtctg
     3721 tctccatgtt gacctagagt cactagagat aaaatgctct aatccccagg tccagctctt
     3781 ctatgaacta actgatatca tgaataaggt ctggaacaag attcagaaga gaggcaatct
     3841 caacctatct ccaacctctc cagagaccat ggcagggcct gttcctactt ctccagttag
     3901 aagcagtata ggcacagctc ctccagatac cagcacatgc agcccatctg ctgacattgg
     3961 gactactact gagggagatt ctatacaagc aggtgaggaa tcaccattct cagattctgt
     4021 gaccttggaa caaactacaa gtaatattgg aggaaccagt ggacgtgtta gtttatggat
     4081 gcagtgggtg cttcccaaaa ttactataaa gctctttgct ccagatcctg aaaataaagg
     4141 cacagaggtt tgtatggtca gtgaactaga agatctcagt gcttccatag atgtccagga
     4201 tgtatatacc aaagtgaaat gtaaaataga gagtttcaat attgatcact atagaagcag
     4261 gccaggggaa ggttggcagt caggacattt tgaaggagta tttctacaat gcaaagaaaa
     4321 atctgtgaca actacaaaac ttctagatgg cactcatcag cagcatggat tcctctctct
     4381 gacatacaca aaagctgtaa caaaaaatgt ccgccacaag ttaacatcaa gaaatgagcg
     4441 aagaagtttt cataagttat ctgaaggcct aatggatggt tctcctcatt ttcttcatga
     4501 aattcttctt tcagcacaag cttttgatat tgttctttat tttcctttac ttaatgccat
     4561 tgcaagtata tttcaagcaa aactaccaaa gacccaaaaa gagaaaagaa aatctcctgg
     4621 tcagcccatg aggacccata cactgacatc ccgcaattta cctttgattt atgtcaacac
     4681 aagtgtaatc agaattttta ttccaaaaac agaagaaatg cagccaactg ttgaagctaa
     4741 tcaggcagca aaagaagaca ctgtggtttt gaagattggc tctgttgcca tggctcccca
     4801 ggctgacaat ccccttggca gatctgtcct taggaaagat atttaccaga gagccttgaa
     4861 cttaggaatt cttcgagatc ctggatcaga aatcgaagac agacaatacc aaatagatct
     4921 gcagtccatc aatattggta ctgcacagtg gcatcaacta aaaccagaga aggaaagtgt
     4981 ctcaggaggg gtggtaacag agactgaaag gaattctcaa aatccagccc ttgagtggaa
     5041 tatggccagc agcatacggc ggcatcaaga aaggagagca attttgaccc ccgttttgac
     5101 agatttttct gtccgaataa ctggagcacc tgctgtcatt ttcaccaaag tagtttctcc
     5161 agaaaatttg catactgagg agattttagt gtgtggccat tccttagaag tgaatataac
     5221 cacaaacctg gacttcttcc taagtgtggc tcaagttcaa ctcttacatc agttaatagt
     5281 agcaaatatg actggactgg aaccatcaaa caaggctgca gagatctcta aacaagaaca
     5341 gaaaaaagtg gatatatttg atggaggcat ggctgaaacc tcatctcgct acagtggtgc
     5401 tcaggatagt ggaattggca gtgacagtgt taaaatcaga atagtgcaaa tagagcagca
     5461 cagtggtgcc agtcagcatc gcattgcccg tccctcacgc cagtcatcaa ttgtaaaaaa
     5521 tctaaatttt attccctttg acatatttat tactgcaagt agaatctcac taatgaccta
     5581 ttcctgtatg gccttatcca aatcgaaatc acaagaacag aagaataatg aaaaaacaga
     5641 caagagttca ttaaatctcc cagaagttga ttcagatgtt gctaagccca accaggcatg
     5701 tatttccacg gtgacagcag aagatctctt aaggagcagc atttcttttc cttcagggaa
     5761 aaaaataggg gtcctctctc ttgaaagtct tcatgcatcc acaaggtcat ctgctagaca
     5821 agcacttggt ataactattg ttcggcagcc tggtcgaaga ggaactggtg acttacagct
     5881 agagcctttt ctgtacttta ttgtgtccca gccttccttg cttctgagtt gtcaccacag
     5941 aaagcagcga gtggaagtat ccatttttga tgctgtgctt aaaggggtgg cctctgatta
     6001 caaatgtata gatcctggga agactctgcc tgaagccctt gattattgca ctgtttggct
     6061 acagacagtg cctggagaaa tagacagcaa aagtggtatt ccaccttcct ttataacact
     6121 acagattaaa gactttctga atggaccagc ggatgtcaat ttggatatat caaagccttt
     6181 gaaagcaaac ctgagtttca ccaaactgga tcagataaac ctttttttaa agaagataaa
     6241 aaatgcacac agtttggcac atagtgaaga gacttcagcc atgtccaaca ccatggtgaa
     6301 taaggatgat cttccagtct ccaaatatta ccgtggaaag ttgtctaaac ccaaaattca
     6361 tggtgatgga gtgcaaaaga tttcagctca agaaaacatg tggagagctg tttcctgctt
     6421 tcaaaaaatt tctgttcaaa ctactcagat tgtgatctcc atggaaactg taccccatac
     6481 cagcaaacca tgcctgttag catctctctc aaacctcaat ggaagcctta gtgtcaaggc
     6541 aacacaaaaa gtacctggca taattcttgg gtcatcattt ctactcagta taaacgattt
     6601 tctccttaaa acaagtctca aagaaagaag ccgcattctg ataggaccat gttgtgctac
     6661 tgccaatctg gaagctaagt ggtgtaaaca cagcgggaat ccaggcccag aacaatccat
     6721 accaaaaata tccattgact taagaggagg tctactacag gtcttctggg gtcaagaaca
     6781 tttgaattgt ttagttcttc tacatgaatt actcaatgga taccttaatg aggagggaaa
     6841 ttttgaagta caagtttctg aaccagtgcc tcaaatgtca tctcctgtgg aaaagaatca
     6901 gacatttaaa agtgaacaaa gttcagatga cctacggaca ggtctatttc agtatgtaca
     6961 ggatgctgaa tctttgaaat tgcctggggt ctatgaagtc ttattttata atgaaactga
     7021 agattgccca gggatgatgt tatggagata tccagaacct agagtactca cccttgtacg
     7081 aataactcct gtacctttta acaccacaga ggatccagat attagcacag cagaccttgg
     7141 tgatgtgcta caggttcctt gtagcttgga atactgggat gaactccaga aggtttttgt
     7201 tgcatttaga gaatttaatc tgtctgaaag caaagtttgt gaactgcagt tgccggatat
     7261 caatctcgtg aatgaccaga agaaattagt atcttcagat ctttggagaa ttgtcttgaa
     7321 cagcagtcaa aatggagctg atgaccaaag ctctgcaagt gagtctggtt ctcaaagcac
     7381 ttgtgatcca cttgtgactc caacagccct ggctgcctgt accagagttg actcctgctt
     7441 taccccatgg tttgtcccat ccctttgcgt ttctttccag tttgctcacc tggaattcca
     7501 tctttgtcat caccttgacc aactaggcac agctgcacca cagtacctac agccatttgt
     7561 ttccgacaga aatatgccat ctgaactaga atacatgatt gtttccttca gagaaccaca
     7621 catgtatctt cgacagtgga ataatggttc tgtctgtcag gagatccagt tcttagctca
     7681 agcagactgt aaacttctag agtgcagaaa tgtcactatg caaagtgtgg tgaaaccctt
     7741 cagcatcttc gggcagatgg cagtttccag cgatgtagtg gaaaagctgc ttgactgcac
     7801 cgtgatagtt gattctgtat ttgtaaacct tggacagcat gtagtccatt cactaaacac
     7861 tgcaatacaa gcttggcaac agaacaaatg ccctgaggta gaggagttgg tcttcagcca
     7921 ttttgtgatc tgtaatgaca cacaggagac actgcggttt ggccaggtgg atactgatga
     7981 aaatattctg ctggcgagtc tccacagtca ccagtacagc tggcgctctc acaaatcccc
     8041 acagctgtta cacatctgta ttgaaggttg gggcaactgg cgttggtcag agcctttcag
     8101 tgtggaccat gccgggactt ttattagaac aattcagtac aggggtcgaa ctgcttctct
     8161 catcatcaag gttcagcaac tcaatggagt acaaaaacag attatcatct gtggaagaca
     8221 gatcatctgt agttacttgt ctcaaagcat agaactaaaa gtcgttcagc attacattgg
     8281 tcaagatgga caagctgtag ttcgggaaca ttttgactgc ctcacagcca aacagaaatt
     8341 gccttcgtac atactagaaa acaatgaact gacggagctg tgtgtgaagg ccaaaggaga
     8401 tgaagactgg tcaagagatg tgtgcctgga atccaaagcc cctgagtaca gcattgtcat
     8461 tcaggtgcca tcttcaaaca gttccattat ttatgtctgg tgcacagttt tgactttaga
     8521 acccaactct caagtgcaac aacgaatgat tgtgttcagc cctcttttta tcatgaggag
     8581 tcatcttcca gaccccatta tcatacattt ggagaaaagg agtctgggat tgagtgaaac
     8641 acaaattatt ccaggaaaag ggcaggaaaa accactgcaa aacatagaac ctgaccttgt
     8701 acatcacctg acattccaag caagagaaga atatgatcct tcagattgtg cagttcccat
     8761 ctcaacatcc ctcattaagc aaatagccac taaggtacac cctggaggca cagttaatca
     8821 gatccttgac gaattctatg ggccagaaaa gtcgcttcaa cccatatggc cctataataa
     8881 gaaggattct gacaggaatg aacagctaag tcagtgggat agcccaatgc gagtgaagct
     8941 gtcaatctgg aagccatatg ttagaacttt gttgatagaa cttctgccct gggccctgct
     9001 tatcaatgaa tccaaatggg acctctggct atttgaagga gagaaaattg ttctacaggt
     9061 tcctgctggc aaaattatta ttcctcctaa ttttcaggaa gcttttcaaa ttggaatata
     9121 ctgggcaaat acaaacactg tgcacaagtc agtagcaatt aaactggtcc ataacctgac
     9181 atctccaaag tggaaagatg gaggtaatgg tgaagttgtg acactggatg aagaagcgtt
     9241 tgttgatact gaaataagac ttggtgcttt tccaggacat cagaagttat gtcagttctg
     9301 catttcctcc atggtacagc aaggtataca aattattcag attgaagaca agactacaat
     9361 aatcaataat acaccatatc aaatatttta taaaccacag ctatctgtct gcaatcccca
     9421 ttctggaaag gagtattttc gtgttccaga cagtgctact tttagcattt gcccaggtgg
     9481 agagcagcct gctatgaaat ccagctccct tccttgctgg gacttgatgc ctgacatcag
     9541 tcagtcagta ctggatgcat ccctgcttca gaaacagatc atgctgggct tttctcctgc
     9601 cccaggtgct gacagctcac agtgctggag cctgccagct atagttagac cagagtttcc
     9661 cagacagagt gtggcagtac ccctcgggaa tttccgggaa aatggattct gtaccagggc
     9721 tatagtgctg acatatcaag aacacctcgg agtgacttat ttaaccctct cagaagaccc
     9781 tagtcctcga gtaattatcc acaatagatg tccagtaaaa atgcttataa aggaaaacat
     9841 taaagatatt ccaaagtttg aggtttattg caaaaaaatt ccctccgagt gctcaattca
     9901 tcatgagctg tatcatcaga tttccagtta tccggactgc aagaccaaag acttacttcc
     9961 aagcctactt ttgagagttg aacctctaga tgaagtaaca actgagtgga gtgatgccat
    10021 tgacatcaac agtcagggaa cacaggttgt gttcctgact ggctttggct atgtgtatgt
    10081 ggatgttgta catcagtgtg gcacagtctt catcactgtg gccccagaag gaaaagcagg
    10141 acctatttta accaatacca acagagcgcc agagaagatt gttacattta aaatgttcat
    10201 cactcagtta agcctggcag tgtttgatga cctcacccac cacaaagcat cagctgagct
    10261 tctgagactc acactggaca acatttttct ctgtgtggcc ccgggagctg gtcccctccc
    10321 tggggaagag cctgtggctg cgttgtttga actttactgt gtggagatct gctgtgggga
    10381 cctgcagcta gacaaccagc tttataacaa gtccaatttc cactttgctg tcttagtctg
    10441 ccagggagaa aaagcagaac ccattcagtg ttccaaaatg cagagtctcc tcatatccaa
    10501 caaagagttg gaagaataca aggaaaaatg ttttatcaaa ctttgcatca ccttaaatga
    10561 aggcaagagc atcctctgtg atattaatga gttcagcttt gaattaaaac ctgctcggtt
    10621 atacgtggaa gacacatttg tatactacat caagactttg tttgacacct accttcctaa
    10681 cagcaggttg gctggtcact ccacacacct ctccgggggt aaacaggtgt tgcccatgca
    10741 ggtcacacag cacgccaggg ccttggtgaa tcctgtgaag ttacggaaac tggtgatcca
    10801 gccagtaaat ttgctcgtca gcatccacgc ttccctcaag ctgtacatag cctcagacca
    10861 cactcctctc tccttctcgg tgtttgaaag aggacccatc ttcaccactg cgaggcagct
    10921 tgtgcacgcc ctggcaatgc actatgccgc tggggccctt tttagagcag gctgggtagt
    10981 tgggtctctg gatattcttg gcagccctgc aagcctggtg agaagcatcg ggaacggggt
    11041 cgccgacttc ttcaggcttc cgtatgaggg gctgacccgg ggccctggag ccttcgtgag
    11101 tggcgtctcc agagggacca catcgtttgt aaagcacatc tccaaaggta ccctcacatc
    11161 catcaccaac ctcgccacaa gcctggcccg gaacatggac cggctctcac tggatgagga
    11221 gcactacaac cggcaggagg agtggcggcg gcagctcccc gagagcctgg gcgaggggct
    11281 tcgacagggc ctgtcccggc tgggcatcag cctgcttggt gcaattgctg gtatagttga
    11341 tcagccgatg cagaacttcc agaaaacatc tgaggcacag gcttcagcag gacacaaggc
    11401 caagggtgtc atctcgggtg tggggaaagg aatcatgggg gtgttcacaa agcccatcgg
    11461 aggagctgct gagctggtgt cacagactgg ctatggtatt ttacatggag ctggactttc
    11521 tcagcttccc aaacagcgcc atcagccaag tgatctacat gctgaccagg ctccaaacag
    11581 ccatgtcaaa tatgtctgga aaatgcttca gtctctgggc agaccagaag tccacatggc
    11641 cctggacgtg gttctggtga ggggctcagg ccaggagcat gaagggtgct tgctgctgac
    11701 atcagaagtg ctcttcgtgg tgagtgtcag tgaggacaca cagcagcagg ccttccccgt
    11761 cacagaaatc gactgtgcac aggacagcaa gcagaacaac ttactcacag tgcagctcaa
    11821 gcagccaaga gtggcctgtg atgtggaggt agatggagtc cgagagagac tgtcagagca
    11881 acagtacaac agactggtgg actacatcac aaagacatct tgtcacctgg cccccagctg
    11941 ttcttccatg caaataccat gccctgtggt ggctgcagaa cctcccccct ccactgttaa
    12001 aacataccat tacctggttg atccacattt tgctcaggtc ttccttagta aatttaccat
    12061 ggtgaaaaat aaagccctga ggaaagggtt tccttgagtc ccctctgagg tgtttattcc
    12121 tgcttgtgtg atttagtttt tgggtttctt tgagacaggg tctcactgca ttgcccttgc
    12181 tgacctcaaa ttctggggtt caagcaatcc tcccacctca acccacaagt agctacgact
    12241 gcaagcacct gccaccataa agggctgcat tttgccacca taaagggctg cattttttta
    12301 aaaagcctag gcagctctaa catcatctga tatggacaca aggccaacag tttccttatt
    12361 tacatcctta cctctaaaag atacttcaaa gtgacaaaaa cgtgttcctt ccccacttag
    12421 agacaatgat taacagggcc ctatatgttc ttaccacata cagaggatgc atttattttt
    12481 gctctatgac acttgcaaaa atctctactg taattaattt gggtctatta ttaactctct
    12541 gttccatcat agaatgtggc caggccttac aatggagagc cagagttaaa acttcaagtt
    12601 gcatctgttt ttgggctgag tcaccacctt tgcctcatgc tcctttgtct gcaaaggcct
    12661 aggattcttt ctttaaatga aatgcttagg actttgtggc ttgttacatt tgtcatttaa
    12721 ctgcagtgct attctttgaa agctgctatg tgtattttct ctgaagtctg cattttacta
    12781 aaatttacaa cagtctgatg attgattgat tactgtccag gtacatttta gaaaaagtgt
    12841 tcttcttcca gtttgtttta ctaagcaaac tttgagtaaa tcctttgtcc tatattgaat
    12901 ccagtcccaa agtgttcagg tgagtttctc tagttccata aacaaaacat acatagtggg
    12961 aactccctgg tatgccatag agcacacaag aaccccaata ttaatgctaa caattatacc
    13021 agtccatttt gtttattctg tggaattgac ttgacaaagc atgaagatat tcccagtgtc
    13081 tgtctgataa tattttgcat ctaagaatgg gtttgactca agatcttggg ttaccaagat
    13141 gtcttaaatg ttcagtaaat atctttctta cagtccagta gcttagagca tgtttgctga
    13201 ttgatattac atttaaactt ggggctacag cttgttacct agaattttga gatactaaga
    13261 gaatgcaatt ttaaatgccc actggtttta tttgttttgg agagagggtc tcattctgtc
    13321 acccaggcta gagtacagtg ggaacagtca tggctcactg cagcttaagc tcactgcctg
    13381 ggctcaagtg atcttactcc agcctcccaa gcagctggga ctacaccacc acaggtatgc
    13441 accaccatac ctggctgatt tttaaaattt tttctagaga tgaggtctca ctatgttgcc
    13501 cagctggtct catactcctc agttcacgca ttcctcccac ctccacctcc caaactgctg
    13561 ggattacagg tgtgagccac catgcccaac acccactgat ctttaactct cacatgttgg
    13621 gcataagaag tcactatata attgttactg gaaagcaaga cttaacgaac aattctgact
    13681 atgaaaaatg tctctttcag tttgttctgt aaatatttag aaaagtgaca gctgtcaacc
    13741 tcagagtaac tatttctaaa aatgtaaata tgtattaatc cttgtatctt ttatggtaat
    13801 tttgcatatt gatatgaatt atataaaatt gtttaaaata aaaggtgtcc ttgaattact
    13861 gaccacccat agatgtctac tgttaccagg ttttacaatg caaattttca ctaatacctg
    13921 ggtttaatac agctcacatc actgaatgtt acacatgagt ttaaatgggt aatatacagg
    13981 ttttgttata ataaagttac tgattaaatt a
//
