LOCUS       NM_014909               6449 bp    mRNA    linear   PRI 03-FEB-2025
DEFINITION  Homo sapiens vasohibin 1 (VASH1), mRNA.
ACCESSION   NM_014909
VERSION     NM_014909.5
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 6449)
  AUTHORS   Eaton,D.M., Lee,B.W., Caporizzo,M.A., Iyengar,A., Chen,C.Y.,
            Uchida,K., Marcellin,G., Lannay,Y., Vite,A., Bedi,K.C. Jr.,
            Brady,C.F., Smolyak,J.N., Meldrum,D., Dominic,J., Weingarten,N.,
            Patel,M., Belec,A., Hached,K., Atluri,P., Van Der Laan,S.,
            Prosser,B.L. and Margulies,K.B.
  TITLE     Vasohibin inhibition improves myocardial relaxation in a rat model
            of heart failure with preserved ejection fraction
  JOURNAL   Sci Transl Med 16 (756), eadm8842 (2024)
   PUBMED   39018366
  REMARK    GeneRIF: Vasohibin inhibition improves myocardial relaxation in a
            rat model of heart failure with preserved ejection fraction.
REFERENCE   2  (bases 1 to 6449)
  AUTHORS   Li,Y., Lou,S., Zhang,J., Zhao,S. and Lou,G.
  TITLE     m6A methylation-mediated regulation of LncRNA MEG3 suppresses
            ovarian cancer progression through miR-885-5p and the VASH1 pathway
  JOURNAL   J Transl Med 22 (1), 113 (2024)
   PUBMED   38281945
  REMARK    GeneRIF: m[6]A methylation-mediated regulation of LncRNA MEG3
            suppresses ovarian cancer progression through miR-885-5p and the
            VASH1 pathway.
            Publication Status: Online-Only
REFERENCE   3  (bases 1 to 6449)
  AUTHORS   Li,Y., Meng,L. and Lou,G.
  TITLE     Revealing the inhibitory effect of VASH1 on ovarian cancer from
            multiple perspectives
  JOURNAL   Cancer Biol Ther 24 (1), 2285817 (2023)
   PUBMED   38010374
  REMARK    GeneRIF: Revealing the inhibitory effect of VASH1 on ovarian cancer
            from multiple perspectives.
REFERENCE   4  (bases 1 to 6449)
  AUTHORS   Feng,M.L., Sun,M.J., Xu,B.Y., Liu,M.Y., Zhang,H.J. and Wu,C.
  TITLE     Mechanism of ELL-associated factor 2 and vasohibin 1 regulating
            invasion, migration, and angiogenesis in colorectal cancer
  JOURNAL   World J Gastroenterol 29 (24), 3770-3792 (2023)
   PUBMED   37426316
  REMARK    GeneRIF: Mechanism of ELL-associated factor 2 and vasohibin 1
            regulating invasion, migration, and angiogenesis in colorectal
            cancer.
REFERENCE   5  (bases 1 to 6449)
  AUTHORS   Wang,W., Shang,W., Zou,J., Liu,K., Liu,M., Qiu,X., Zhang,H.,
            Wang,K. and Wang,N.
  TITLE     ZNF667 facilitates angiogenesis after myocardial ischemia through
            transcriptional regulation of VASH1 and Wnt signaling pathway
  JOURNAL   Int J Mol Med 50 (4) (2022)
   PUBMED   36043524
  REMARK    GeneRIF: ZNF667 facilitates angiogenesis after myocardial ischemia
            through transcriptional regulation of VASH1 and Wnt signaling
            pathway.
REFERENCE   6  (bases 1 to 6449)
  AUTHORS   Yamashita,H., Abe,M., Watanabe,K., Shimizu,K., Moriya,T., Sato,A.,
            Satomi,S., Ohta,H., Sonoda,H. and Sato,Y.
  TITLE     Vasohibin prevents arterial neointimal formation through
            angiogenesis inhibition
  JOURNAL   Biochem Biophys Res Commun 345 (3), 919-925 (2006)
   PUBMED   16707096
  REMARK    GeneRIF: vasohibin has an activity to prevent neointimal formation
            by inhibiting adventitial angiogenesis
REFERENCE   7  (bases 1 to 6449)
  AUTHORS   Sonoda,H., Ohta,H., Watanabe,K., Yamashita,H., Kimura,H. and
            Sato,Y.
  TITLE     Multiple processing forms and their biological activities of a
            novel angiogenesis inhibitor vasohibin
  JOURNAL   Biochem Biophys Res Commun 342 (2), 640-646 (2006)
   PUBMED   16488400
  REMARK    GeneRIF: Recombinant amino-terminal truncated forms of vasohibin
            retain inhibitory activity of angiogenesis in mouse corneal assay
            and show strong affinity to heparin.
REFERENCE   8  (bases 1 to 6449)
  AUTHORS   Shimizu,K., Watanabe,K., Yamashita,H., Abe,M., Yoshimatsu,H.,
            Ohta,H., Sonoda,H. and Sato,Y.
  TITLE     Gene regulation of a novel angiogenesis inhibitor, vasohibin, in
            endothelial cells
  JOURNAL   Biochem Biophys Res Commun 327 (3), 700-706 (2005)
   PUBMED   15649403
REFERENCE   9  (bases 1 to 6449)
  AUTHORS   Watanabe,K., Hasegawa,Y., Yamashita,H., Shimizu,K., Ding,Y.,
            Abe,M., Ohta,H., Imagawa,K., Hojo,K., Maki,H., Sonoda,H. and
            Sato,Y.
  TITLE     Vasohibin as an endothelium-derived negative feedback regulator of
            angiogenesis
  JOURNAL   J Clin Invest 114 (7), 898-907 (2004)
   PUBMED   15467828
  REMARK    GeneRIF: Results suggest that KIAA1036, or vasohibin, is an
            endothelium-derived negative feedback regulator of angiogenesis
            [vasohibin]
REFERENCE   10 (bases 1 to 6449)
  AUTHORS   Heilig,R., Eckenberg,R., Petit,J.L., Fonknechten,N., Da Silva,C.,
            Cattolico,L., Levy,M., Barbe,V., de Berardinis,V., Ureta-Vidal,A.,
            Pelletier,E., Vico,V., Anthouard,V., Rowen,L., Madan,A., Qin,S.,
            Sun,H., Du,H., Pepin,K., Artiguenave,F., Robert,C., Cruaud,C.,
            Bruls,T., Jaillon,O., Friedlander,L., Samson,G., Brottier,P.,
            Cure,S., Segurens,B., Aniere,F., Samain,S., Crespeau,H., Abbasi,N.,
            Aiach,N., Boscus,D., Dickhoff,R., Dors,M., Dubois,I., Friedman,C.,
            Gouyvenoux,M., James,R., Madan,A., Mairey-Estrada,B., Mangenot,S.,
            Martins,N., Menard,M., Oztas,S., Ratcliffe,A., Shaffer,T.,
            Trask,B., Vacherie,B., Bellemere,C., Belser,C., Besnard-Gonnet,M.,
            Bartol-Mavel,D., Boutard,M., Briez-Silla,S., Combette,S.,
            Dufosse-Laurent,V., Ferron,C., Lechaplais,C., Louesse,C.,
            Muselet,D., Magdelenat,G., Pateau,E., Petit,E.,
            Sirvain-Trukniewicz,P., Trybou,A., Vega-Czarny,N., Bataille,E.,
            Bluet,E., Bordelais,I., Dubois,M., Dumont,C., Guerin,T.,
            Haffray,S., Hammadi,R., Muanga,J., Pellouin,V., Robert,D.,
            Wunderle,E., Gauguet,G., Roy,A., Sainte-Marthe,L., Verdier,J.,
            Verdier-Discala,C., Hillier,L., Fulton,L., McPherson,J.,
            Matsuda,F., Wilson,R., Scarpelli,C., Gyapay,G., Wincker,P.,
            Saurin,W., Quetier,F., Waterston,R., Hood,L. and Weissenbach,J.
  TITLE     The DNA sequence and analysis of human chromosome 14
  JOURNAL   Nature 421 (6923), 601-607 (2003)
   PUBMED   12508121
  REMARK    Erratum:[Nature. 2023 Aug;620(7973):E17. doi:
            10.1038/s41586-023-06403-y.. PMID: 37491470]
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC007376.9, BE674799.1, AL832588.2, BC051896.1, AB028959.1 and
            BF741850.1.
            
            On Nov 24, 2018 this sequence version replaced NM_014909.4.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AL832588.2, AB028959.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA1965299, SAMEA1966682
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000167106.9/ ENSP00000167106.4
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-424               AC007376.9         161853-162276
            425-721             BE674799.1         1-297
            722-1292            AL832588.2         2-572
            1293-2648           BC051896.1         163-1518
            2649-2823           AL832588.2         1929-2103
            2824-3848           AB028959.1         1855-2879
            3849-4003           BF741850.1         210-364
            4004-4225           AL832588.2         3283-3504
            4226-6449           AB028959.1         3257-5480
FEATURES             Location/Qualifiers
     source          1..6449
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="14"
                     /map="14q24.3"
     gene            1..6449
                     /gene="VASH1"
                     /gene_synonym="KIAA1036; TTCP 1"
                     /note="vasohibin 1"
                     /db_xref="GeneID:22846"
                     /db_xref="HGNC:HGNC:19964"
                     /db_xref="MIM:609011"
     exon            1..1663
                     /gene="VASH1"
                     /gene_synonym="KIAA1036; TTCP 1"
                     /inference="alignment:Splign:2.1.0"
     CDS             1355..2452
                     /gene="VASH1"
                     /gene_synonym="KIAA1036; TTCP 1"
                     /EC_number="3.4.17.17"
                     /note="tubulin carboxypeptidase 1; tyrosine
                     carboxypeptidase 1"
                     /codon_start=1
                     /product="tubulinyl-Tyr carboxypeptidase 1"
                     /protein_id="NP_055724.1"
                     /db_xref="CCDS:CCDS9851.1"
                     /db_xref="GeneID:22846"
                     /db_xref="HGNC:HGNC:19964"
                     /db_xref="MIM:609011"
                     /translation="MPGGKKVAGGGSSGATPTSAAATAPSGVRRLETSEGTSAQRDEE
                     PEEEGEEDLRDGGVPFFVNRGGLPVDEATWERMWKHVAKIHPDGEKVAQRIRGATDLP
                     KIPIPSVPTFQPSTPVPERLEAVQRYIRELQYNHTGTQFFEIKKSRPLTGLMDLAKEM
                     TKEALPIKCLEAVILGIYLTNSMPTLERFPISFKTYFSGNYFRHIVLGVNFAGRYGAL
                     GMSRREDLMYKPPAFRTLSELVLDFEAAYGRCWHVLKKVKLGQSVSHDPHSVEQIEWK
                     HSVLDVERLGRDDFRKELERHARDMRLKIGKGTGPPSPTKDRKKDVSSPQRAQSSPHR
                     RNSRSERRPSGDKKTSEPKAMPDLNGYQIRV"
     exon            1664..1752
                     /gene="VASH1"
                     /gene_synonym="KIAA1036; TTCP 1"
                     /inference="alignment:Splign:2.1.0"
     exon            1753..1809
                     /gene="VASH1"
                     /gene_synonym="KIAA1036; TTCP 1"
                     /inference="alignment:Splign:2.1.0"
     exon            1810..1884
                     /gene="VASH1"
                     /gene_synonym="KIAA1036; TTCP 1"
                     /inference="alignment:Splign:2.1.0"
     exon            1885..2266
                     /gene="VASH1"
                     /gene_synonym="KIAA1036; TTCP 1"
                     /inference="alignment:Splign:2.1.0"
     exon            2267..2379
                     /gene="VASH1"
                     /gene_synonym="KIAA1036; TTCP 1"
                     /inference="alignment:Splign:2.1.0"
     exon            2380..6449
                     /gene="VASH1"
                     /gene_synonym="KIAA1036; TTCP 1"
                     /inference="alignment:Splign:2.1.0"
     polyA_site      6449
                     /gene="VASH1"
                     /gene_synonym="KIAA1036; TTCP 1"
                     /note="major polyA site"
ORIGIN      
        1 gcgggccgta gtcgagcctg gtgggcggct ggctggcagg ggacgtggtc ggcggcagcg
       61 gggcccaggg gcggcggggc tgcagcagcg gcggccccag cttcgccgag cagcgatcgg
      121 ctggtgggct tctcgttggc gggctccgcg ttggcgggct gctccccagg caccagcgca
      181 gcgcgcgctc gcccggcttc gtcactcgcc tccagctaca tccgccggcc gaggctgcgc
      241 gagcctccgg gcttgcggtc cccgccccgc ggtccttcct ccaccctcag ccagggcagc
      301 tgcagcccga gcgaacagcc acggagcatc ctccgcccgc ccgggccgcg ccaccgccca
      361 tgctgcagcc agtcccaggc agcgaccccg cggccgcagc ccgccgctca gtgacctcag
      421 cctggcccct gcgcgccgcc cgagccggtc ccgctgagcc gcgggccccg tgccctgcga
      481 tggctcggct ggtgcagcgc ggcgccaggt gccagccgtc ctcccgctga gacgcgcccg
      541 agtggggacc cgctgggcct cggggctcgc agccttcgcc tccccgccgc gcccgctccc
      601 tttctgggga ctccgccgct gtttctgggg acgaggggac aggggaccca gacaaagccc
      661 actttgtgca gggagttggc cgcaggcggg gaatgtgcgc gtcggcgcgc gccccctccc
      721 cgctcccggc cagctgcgag tcttggctcc cggacttgtc tcgtcgcgtc ggagaaatcg
      781 ccccccagcg ccgctctccc gcccgggggt cttggttccg agctcgcgcg gccgggagtc
      841 gcctcggtct tccttggggc gcgcgcagat gtgagcgtgc gagagttgtg taggggattt
      901 tgttccctcc gaaactgaga cccagggcgc ccagtgggca cccgtgcctt gactctgtcc
      961 tttctgcagc cgctggtccg agctgtctgg cctcagtttc cctccgactt ttctccgctc
     1021 tgccagccct cactgctgcc cgtcattgtt ctcgcagtta gatgggggtg ctttgtgacg
     1081 gctgccaagt tggggtgtgt tctctttatt ccgtttttca aacagaacaa ggcctccaag
     1141 gctgacccca gacaacccac cccctcggac cctaattcac cttattgcac tgattttttt
     1201 tatcaagtcg tattttattg tacaggagcc acgccctgat ttcttaaagg cgccttgcac
     1261 tctggccatg tgttatctct gcagccggtg tgtgggaggc ctcttgtgag ccagttgttt
     1321 tcccgcctcc accacccccc tcgaagattt agggatgcca ggggggaaga aggtggctgg
     1381 gggtggcagc agcggtgcca ctccaacgtc cgctgcggcc accgccccct ctggggtcag
     1441 gcgtttggag accagcgaag gaacctcagc ccagagagat gaggagccag aagaggaagg
     1501 ggaagaggac ctgcgagacg gaggcgtccc cttctttgtc aaccggggtg ggctacctgt
     1561 ggatgaggcc acctgggaaa ggatgtggaa acacgtggcc aagatccacc ccgatggaga
     1621 gaaggtggcg caacggatcc gtggggccac agacctgccc aagatcccca taccgagtgt
     1681 gcctacgttc cagccgtcta cacctgtccc tgagcgcctg gaagctgtgc agcgctacat
     1741 cagagagctg cagtacaatc acacagggac acagttcttt gaaattaaga agagcagacc
     1801 tctgacaggg ctgatggacc tggccaagga aatgaccaaa gaggccctgc caatcaaatg
     1861 cctggaagcc gtgatcctgg gaatttacct caccaacagc atgcccaccc tggagcgctt
     1921 ccccatcagc ttcaagacct acttctcagg gaactacttc cgccacatcg tgctgggggt
     1981 gaacttcgcg ggccgctacg gtgcgctggg catgagtcgg cgcgaggacc tgatgtacaa
     2041 gccgcccgcc ttccgcacgc tcagcgagct cgtgctggac ttcgaggccg cctacggccg
     2101 ctgctggcac gtgctcaaga aggtgaagct gggccagagc gtgtcacacg acccgcacag
     2161 cgtggagcag atcgagtgga agcactcggt gctggacgtg gagcgcctgg gccgcgatga
     2221 cttccgcaag gagctggagc gccacgcccg cgacatgcgg ctcaagattg gcaaagggac
     2281 gggccctccc tctcccacca aggaccggaa gaaggatgtt tcttccccgc agcgggccca
     2341 gtccagcccc caccgcagga acagccgcag tgaaagacgg ccctcgggtg acaagaagac
     2401 ttccgagccc aaagccatgc cagaccttaa cgggtaccag atccgggtct gaggcggatg
     2461 ccagcacccc aggccccacc cactcttggg ggccaggatc cacctgctgg aaccagcctt
     2521 atgcatgggg aaggcggggc tggtgacaag gcagggcaag aggctgcagg aagagtgtgt
     2581 tccagctcag ccccccaagc tgctctcgct cccactgagc caagccccct aactttgggc
     2641 ctagaggccg ttagtatttt atttggagtt tttaactcta caactgaagt ttaaggtatt
     2701 tggggaaaac ttagtccaaa tggatctgct gatggtggga aggccagtgc ttaacaaatc
     2761 catgtgtcat ggggccaggt gagggaaact gctggttctg ctggtgcctc tgcccctggc
     2821 ttctctctgg gagttgggtg catcttatca gtgggaaatc tcccagcctt accaggcctg
     2881 tgatgggggg tgggggtggg gtggagatgt ttctccagtt ctgcctgccc tggcagaatc
     2941 ttgacccagg gaaagggaag cagggtagga gtccttctga gaaaggtctg tgtagcccat
     3001 taaccaggag cttggcacag gccacatctg ccccaagagc atgagctcgt ggctcaggag
     3061 agccttcagg cccttgaggc ccccatgggc agtgctgtgt gggcagagga ggggtgatat
     3121 gagagcgagc ccagggaagg acctctgggc aaaaagttcc caggccctaa ctgcgtctac
     3181 ttgctcagtc ccagctctgc ctgttgctct agcccacagg ctccctgcgg agggtctggg
     3241 cttggcggag gacccagaat ggcactgagg ccagcatggc tgtgggagtt gagcaaaccc
     3301 tgggtgccag tccaggagct gtggctggac atggggtgat ggggcgggat gcttgggcct
     3361 gggtctctcc gccagcagtg ccaggagccc ttgctgggga aatcaagacc agactaggat
     3421 gcttctgccc caggcctgcc ttccattctt taacagccca tcttggcttg gggttgcaat
     3481 gatggctggg ccagtcactt gtggcagggc atcagggccc tggcagggaa gaacctaggc
     3541 acctggggtt gtccccagcc tgcccgtcag catgagatac ccagtgggaa agtgagagga
     3601 tgcggagagg ttggcagagc caggggtagg ttctggaggc tcaagcaaca aggaggtgca
     3661 ggtaaagggt gcagtgcagc cactgaggga cagctgggaa ctgggggatg caagtgagaa
     3721 agggatgtgg gggagagttc aggatcaggc tgcttgagga gtaatgggtt acctacagca
     3781 gagacgagat ggctgtttgt caggaggcgg tagaaaggta gaaaggattc agattgtgga
     3841 agggtaaacg gatgagatga ccattaaggt tttgttttac tgagaggctg taagtctgcc
     3901 agggacagct gtcagtaagg ctgcagaagg gctggggggc tacacaagga agagcagaac
     3961 tagggttgta agctcaaatg acgagcaaac ggtgagaagg aggcctgaag ggctgtgtgg
     4021 ggactatggc tacctgaaga gggcacaccc tgttaaaggg gccacagctg ctcagctgtt
     4081 cttacagtgc cggccctgtg ttgccagatt gtctgctttg tcagaggcca gaattctgac
     4141 tttttatgtg aaataggatt tttaaatgct ggtgatcact taaaaaaaac ttaaaaaccc
     4201 aatactggca aaagaggatg ccagtttgca atccctgaag tagagagagc tcgtgctggg
     4261 gagaagtcca ccaagatgct ttgaggcggg ctgtagcaaa gtcctgtttc tcagagctgg
     4321 gctgggctgg ggtaggatcc ttgcagctga ggaggaggaa aagccactga gtctcctccc
     4381 agagcgggac aaaccagagg ccctttgcag ttgctgggtc accagcgggg gtggcgcatg
     4441 gagtacagac agtgtagctc ttggcctgcc agggagacgg atggtgcctt tgaagcaaag
     4501 aggaagggaa ggcagaacca gggatgcctt tgctgatgag agtgcctgtc agggaaggcg
     4561 ccacaggctg gcagctcttc aaaccagcag cgcttgaccc agagccagat ccagcatggc
     4621 ctggccagag gcaccctggg aggccagctg gtcagtccct tgcctcccca agttccccct
     4681 ggggtcaatg agccctggga ggatgcctaa cctaactcca gccagactaa taggggcatg
     4741 gtgacccttg actcaccatc ccatcccagc tttcagggag tgggggtagt gtggtctcca
     4801 tgttcctact atgcctaaga agagatggct caccttggga ggtgccaggc tgaaactagg
     4861 tcctttccgg gtctggatgc tgccgctcag gagcaggggc gtggcctcag ctgcctctgg
     4921 gagcttcccg ggaatgacag ggtttgaggg gagtagatat gagagggagc cgctcctggt
     4981 tctggagtct taggaggttc caacttgcag gatcctttcc cagagccctc catggagaaa
     5041 acagcaaaat gaagccctta cctgcttgct gtctgcaagg gagggagccg agccccagct
     5101 gataatcccc cagcactcac ccttcctgag ctgagacttc ggggctgtgg agaccagcac
     5161 aggacatagt ggtgcttttt aaatttattt ttaactgttt ctcatatgta gcaacccctc
     5221 ctcccctcct gggcatgttt acacaggctc tgctctgggg gctggcctgg ctgtgaggtt
     5281 tctggggagg cagagaggca gggactttgg ggccttagtc accatccatg gtatcacctc
     5341 atctcacttc ctgtgaggga cagggcctgg ctgatgtgat cccagctccc cccagttcag
     5401 gactgtcttt cagctccttt gcccctggag gtgggggctg ctggctgagg aggggtcaag
     5461 gtgagttcaa gaaagctacc tgtggaaaat ggaccaggtt gggggggtga ttgcaaagtc
     5521 tccccaaagc ctggctcctc atgctcagtg ccaggggcag aacactgggg agccaggtat
     5581 agagagcctt cctgtcataa ctgccagtcc tcttcctcca aggcctctgc atattctcat
     5641 gttcccctca cccatcatgc cagccacccc tatccctctt ctagcagggc caagatgggg
     5701 acagcagcag ccctctggcc ttgggatgtg atgataaagc aagcctaggg ccagggtttg
     5761 gggagcagag agagccaaga agttgaccac gtgtgatttc cagcccttcc cactgggact
     5821 tgacttccca ggtcaaggag tccgtctcat tctggctggt cgagtgacca gaggcctgtg
     5881 tgaatgtgtg cacctgcttt tcctgcctgg aatgttttct ggctcagctg cagcaacatc
     5941 tgtgagccca gtgtctgccc tgtgtccctg ggctcgctcc aagtgcagga acatacatgc
     6001 agggcccaac atgatgatgg tgtgaagggc aggaaacagt cctctgaagg agtggggagg
     6061 tgggcagtct gcccccgcca ggtaccatcg cctcctgcca gcttccttag accaggcagg
     6121 gctgccatgg tgctagctgc aagtccatca gtattgaccg tctcgctcca tcttggtcct
     6181 ccggagtccc aagtttcctt ttcatcaaat ctgacaagag agaagaaaca tgggtgtgct
     6241 tggcccacag ggcctggtgg tgatggacct ccccgctccc tcaagctctg gatggctgca
     6301 gtgttgtact agactttgtt caggctgttc tcatctcagt attgcccctt cctttcactt
     6361 tcacacttca tctcattcct gttgtcactt tccccgaaac gaataaagtc tccccagctc
     6421 ctgctgtgta ggctgggcag aaaccacaa
//
