LOCUS       NM_007124              12918 bp    mRNA    linear   PRI 23-APR-2024
DEFINITION  Homo sapiens utrophin (UTRN), transcript variant 1, mRNA.
ACCESSION   NM_007124 XM_011536106
VERSION     NM_007124.3
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 12918)
  AUTHORS   Song,W., Li,Z., Xia,M. and Xiao,W.
  TITLE     Regulation of Drp1 and enhancement of mitochondrial fission by the
            deubiquitinating enzyme PSMD14 facilitates the proliferation of
            bladder cancer cells
  JOURNAL   Oncol Rep 51 (1) (2024)
   PUBMED   37975230
  REMARK    GeneRIF: Regulation of Drp1 and enhancement of mitochondrial
            fission by the deubiquitinating enzyme PSMD14 facilitates the
            proliferation of bladder cancer cells.
REFERENCE   2  (bases 1 to 12918)
  AUTHORS   Wang,L., Feng,J., Feng,X., Meng,D., Zhao,X., Wang,J., Yu,P.,
            Xu,G.E., Hu,M., Wang,T., Lehmann,H.I., Li,G., Sluijter,J.P.G. and
            Xiao,J.
  TITLE     Exercise-induced circular RNA circUtrn is required for cardiac
            physiological hypertrophy and prevents myocardial
            ischaemia-reperfusion injury
  JOURNAL   Cardiovasc Res 119 (16), 2638-2652 (2023)
   PUBMED   37897547
  REMARK    GeneRIF: Exercise-induced circular RNA circUtrn is required for
            cardiac physiological hypertrophy and prevents myocardial
            ischaemia-reperfusion injury.
REFERENCE   3  (bases 1 to 12918)
  AUTHORS   Liu,M., Gong,C., Shen,X., Jiang,Y., Xu,Y., Zhong,W., Chen,Y.,
            Dong,N., Liao,J. and Yin,N.
  TITLE     Mitochondrial dynamics-related genes DRP1 and OPA1 contributes to
            early diagnosis of cognitive impairment in diabetes
  JOURNAL   BMC Geriatr 23 (1), 484 (2023)
   PUBMED   37563583
  REMARK    GeneRIF: Mitochondrial dynamics-related genes DRP1 and OPA1
            contributes to early diagnosis of cognitive impairment in diabetes.
            Publication Status: Online-Only
REFERENCE   4  (bases 1 to 12918)
  AUTHORS   Gao,T., Shi,R., Liu,Z., De,D., Li,R., Chen,Y., Pei,J. and Ding,M.
  TITLE     Ischemia/reperfusion-induced MiD51 upregulation recruits Drp1 to
            mitochondria and contributes to myocardial injury
  JOURNAL   Biochem Biophys Res Commun 665, 78-87 (2023)
   PUBMED   37149986
  REMARK    GeneRIF: Ischemia/reperfusion-induced MiD51 upregulation recruits
            Drp1 to mitochondria and contributes to myocardial injury.
REFERENCE   5  (bases 1 to 12918)
  AUTHORS   Hu,Z., Zhang,H., Wang,Y., Li,B., Liu,K., Ran,J. and Li,L.
  TITLE     Exercise activates Sirt1-mediated Drp1 acetylation and inhibits
            hepatocyte apoptosis to improve nonalcoholic fatty liver disease
  JOURNAL   Lipids Health Dis 22 (1), 33 (2023)
   PUBMED   36882837
  REMARK    GeneRIF: Exercise activates Sirt1-mediated Drp1 acetylation and
            inhibits hepatocyte apoptosis to improve nonalcoholic fatty liver
            disease.
            Publication Status: Online-Only
REFERENCE   6  (bases 1 to 12918)
  AUTHORS   Tinsley,J.M., Blake,D.J., Roche,A., Fairbrother,U., Riss,J.,
            Byth,B.C., Knight,A.E., Kendrick-Jones,J., Suthers,G.K., Love,D.R.
            et al.
  TITLE     Primary structure of dystrophin-related protein
  JOURNAL   Nature 360 (6404), 591-593 (1992)
   PUBMED   1461283
REFERENCE   7  (bases 1 to 12918)
  AUTHORS   Nguyen,T.M., Le,T.T., Blake,D.J., Davies,K.E. and Morris,G.E.
  TITLE     Utrophin, the autosomal homologue of dystrophin, is
            widely-expressed and membrane-associated in cultured cell lines
  JOURNAL   FEBS Lett 313 (1), 19-22 (1992)
   PUBMED   1426262
REFERENCE   8  (bases 1 to 12918)
  AUTHORS   Khurana,T.S., Watkins,S.C. and Kunkel,L.M.
  TITLE     The subcellular distribution of chromosome 6-encoded
            dystrophin-related protein in the brain
  JOURNAL   J Cell Biol 119 (2), 357-366 (1992)
   PUBMED   1400579
REFERENCE   9  (bases 1 to 12918)
  AUTHORS   Love,D.R., Morris,G.E., Ellis,J.M., Fairbrother,U., Marsden,R.F.,
            Bloomfield,J.F., Edwards,Y.H., Slater,C.P., Parry,D.J. and
            Davies,K.E.
  TITLE     Tissue distribution of the dystrophin-related gene product and
            expression in the mdx and dy mouse
  JOURNAL   Proc Natl Acad Sci U S A 88 (8), 3243-3247 (1991)
   PUBMED   2014247
REFERENCE   10 (bases 1 to 12918)
  AUTHORS   Buckle,V.J., Guenet,J.L., Simon-Chazottes,D., Love,D.R. and
            Davies,K.E.
  TITLE     Localisation of a dystrophin-related autosomal gene to 6q24 in man,
            and to mouse chromosome 10 in the region of the dystrophia
            muscularis (dy) locus
  JOURNAL   Hum Genet 85 (3), 324-326 (1990)
   PUBMED   2203673
COMMENT     REVIEWED REFSEQ: This record has been curated by NCBI staff. The
            reference sequence was derived from AL024474.1, AL590704.13,
            AL590488.13, AL513475.13, AL513184.7 and AL357149.13.
            This sequence is a reference standard in the RefSeqGene project.
            
            On or before Jan 22, 2021 this sequence version replaced
            XM_011536106.2, NM_007124.2.
            
            Summary: This gene shares both structural and functional
            similarities with the dystrophin gene. It contains an actin-binding
            N-terminus, a triple coiled-coil repeat central region, and a
            C-terminus that consists of protein-protein interaction motifs
            which interact with dystroglycan protein components. The protein
            encoded by this gene is located at the neuromuscular synapse and
            myotendinous junctions, where it participates in post-synaptic
            membrane maintenance and acetylcholine receptor clustering. Mouse
            studies suggest that this gene may serve as a functional substitute
            for the dystrophin gene and therefore, may serve as a potential
            therapeutic alternative to muscular dystrophy which is caused by
            mutations in the dystrophin gene. Alternative splicing of the
            utrophin gene has been described; however, the full-length nature
            of these variants has not yet been determined. [provided by RefSeq,
            Jul 2008].
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            CDS exon combination :: X69086.1 [ECO:0000331]
            RNAseq introns       :: single sample supports all introns
                                    SAMEA1966682, SAMEA1968540 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            inferred exon combination :: based on alignments, homology
            MANE Ensembl match        :: ENST00000367545.8/ ENSP00000356515.3
            RefSeq Select criteria    :: based on manual assertion,
                                         conservation, expression, longest
                                         protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-487               AL024474.1         29878-30364
            488-658             AL024474.1         36280-36450
            659-720             AL590704.13        54399-54460
            721-813             AL590488.13        14057-14149
            814-891             AL590488.13        15728-15805
            892-984             AL590488.13        16165-16257
            985-1157            AL590488.13        18466-18638
            1158-1273           AL590488.13        20957-21072
            1274-1434           AL590488.13        21760-21920
            1435-1638           AL590488.13        28114-28317
            1639-1820           AL590488.13        29744-29925
            1821-1971           AL590488.13        30924-31074
            1972-2091           AL590488.13        32531-32650
            2092-2193           AL590488.13        36460-36561
            2194-2301           AL590488.13        39390-39497
            2302-2481           AL590488.13        39781-39960
            2482-2651           AL590488.13        40779-40948
            2652-2775           AL590488.13        43549-43672
            2776-2863           AL590488.13        45961-46048
            2864-3105           AL590488.13        50949-51190
            3106-3286           AL590488.13        51353-51533
            3287-3432           AL590488.13        53376-53521
            3433-3645           AL590488.13        54833-55045
            3646-3759           AL590488.13        65899-66012
            3760-3915           AL590488.13        66783-66938
            3916-4086           AL590488.13        71991-72161
            4087-4266           AL590488.13        74388-74567
            4267-4401           AL590488.13        77564-77698
            4402-4551           AL590488.13        79727-79876
            4552-4713           AL590488.13        80852-81013
            4714-4842           AL590488.13        82250-82378
            4843-5016           AL590488.13        83108-83281
            5017-5172           AL590488.13        85480-85635
            5173-5343           AL590488.13        91436-91606
            5344-5523           AL590488.13        103123-103302
            5524-5652           AL590488.13        106088-106216
            5653-5823           AL590488.13        106829-106999
            5824-5982           AL590488.13        108408-108566
            5983-6120           AL590488.13        108990-109127
            6121-6312           AL590488.13        114159-114350
            6313-6485           AL590488.13        115195-115367
            6486-6636           AL590488.13        123231-123381
            6637-6812           AL590488.13        125264-125439
            6813-6948           AL513475.13        2282-2417
            6949-7098           AL513475.13        3994-4143
            7099-7174           AL513475.13        7495-7570
            7175-7389           AL513475.13        13340-13554
            7390-7507           AL513475.13        15665-15782
            7508-7713           AL513475.13        19388-19593
            7714-7868           AL513475.13        21857-22011
            7869-8058           AL513475.13        41799-41988
            8059-8231           AL513475.13        143106-143278
            8232-8388           AL513475.13        164787-164943
            8389-8518           AL513184.7         3405-3534
            8519-8787           AL513184.7         21294-21562
            8788-8934           AL513184.7         24854-25000
            8935-9013           AL513184.7         27768-27846
            9014-9074           AL513184.7         30977-31037
            9075-9136           AL513184.7         44955-45016
            9137-9211           AL513184.7         47338-47412
            9212-9413           AL513184.7         54970-55171
            9414-9499           AL513184.7         62242-62327
            9500-9657           AL513184.7         66882-67039
            9658-9824           AL513184.7         70872-71038
            9825-9936           AL513184.7         76084-76195
            9937-10073          AL357149.13        12569-12705
            10074-10112         AL357149.13        19035-19073
            10113-10178         AL357149.13        19298-19363
            10179-10244         AL357149.13        20477-20542
            10245-10403         AL357149.13        27467-27625
            10404-10644         AL357149.13        27988-28228
            10645-10756         AL357149.13        30860-30971
            10757-10849         AL357149.13        32427-32519
            10850-10872         AL357149.13        38492-38514
            10873-12918         AL357149.13        42676-44721
FEATURES             Location/Qualifiers
     source          1..12918
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="6"
                     /map="6q24.2"
     gene            1..12918
                     /gene="UTRN"
                     /gene_synonym="DMDL; DRP; DRP1"
                     /note="utrophin"
                     /db_xref="GeneID:7402"
                     /db_xref="HGNC:HGNC:12635"
                     /db_xref="MIM:128240"
     exon            1..487
                     /gene="UTRN"
                     /gene_synonym="DMDL; DRP; DRP1"
                     /inference="alignment:Splign:2.1.0"
     exon            488..658
                     /gene="UTRN"
                     /gene_synonym="DMDL; DRP; DRP1"
                     /inference="alignment:Splign:2.1.0"
     CDS             580..10881
                     /gene="UTRN"
                     /gene_synonym="DMDL; DRP; DRP1"
                     /note="isoform 1 is encoded by transcript variant 1;
                     dystrophin-related protein 1"
                     /codon_start=1
                     /product="utrophin isoform 1"
                     /protein_id="NP_009055.2"
                     /db_xref="CCDS:CCDS34547.1"
                     /db_xref="GeneID:7402"
                     /db_xref="HGNC:HGNC:12635"
                     /db_xref="MIM:128240"
                     /translation="MAKYGEHEASPDNGQNEFSDIIKSRSDEHNDVQKKTFTKWINAR
                     FSKSGKPPINDMFTDLKDGRKLLDLLEGLTGTSLPKERGSTRVHALNNVNRVLQVLHQ
                     NNVELVNIGGTDIVDGNHKLTLGLLWSIILHWQVKDVMKDVMSDLQQTNSEKILLSWV
                     RQTTRPYSQVNVLNFTTSWTDGLAFNAVLHRHKPDLFSWDKVVKMSPIERLEHAFSKA
                     QTYLGIEKLLDPEDVAVQLPDKKSIIMYLTSLFEVLPQQVTIDAIREVETLPRKYKKE
                     CEEEAINIQSTAPEEEHESPRAETPSTVTEVDMDLDSYQIALEEVLTWLLSAEDTFQE
                     QDDISDDVEEVKDQFATHEAFMMELTAHQSSVGSVLQAGNQLITQGTLSDEEEFEIQE
                     QMTLLNARWEALRVESMDRQSRLHDVLMELQKKQLQQLSAWLTLTEERIQKMETCPLD
                     DDVKSLQKLLEEHKSLQSDLEAEQVKVNSLTHMVVIVDENSGESATAILEDQLQKLGE
                     RWTAVCRWTEERWNRLQEINILWQELLEEQCLLKAWLTEKEEALNKVQTSNFKDQKEL
                     SVSVRRLAILKEDMEMKRQTLDQLSEIGQDVGQLLDNSKASKKINSDSEELTQRWDSL
                     VQRLEDSSNQVTQAVAKLGMSQIPQKDLLETVRVREQAITKKSKQELPPPPPPKKRQI
                     HVDIEAKKKFDAISAELLNWILKWKTAIQTTEIKEYMKMQDTSEMKKKLKALEKEQRE
                     RIPRADELNQTGQILVEQMGKEGLPTEEIKNVLEKVSSEWKNVSQHLEDLERKIQLQE
                     DINAYFKQLDELEKVIKTKEEWVKHTSISESSRQSLPSLKDSCQRELTNLLGLHPKIE
                     MARASCSALMSQPSAPDFVQRGFDSFLGRYQAVQEAVEDRQQHLENELKGQPGHAYLE
                     TLKTLKDVLNDSENKAQVSLNVLNDLAKVEKALQEKKTLDEILENQKPALHKLAEETK
                     ALEKNVHPDVEKLYKQEFDDVQGKWNKLKVLVSKDLHLLEEIALTLRAFEADSTVIEK
                     WMDGVKDFLMKQQAAQGDDAGLQRQLDQCSAFVNEIETIESSLKNMKEIETNLRSGPV
                     AGIKTWVQTRLGDYQTQLEKLSKEIATQKSRLSESQEKAANLKKDLAEMQEWMTQAEE
                     EYLERDFEYKSPEELESAVEEMKRAKEDVLQKEVRVKILKDNIKLLAAKVPSGGQELT
                     SELNVVLENYQLLCNRIRGKCHTLEEVWSCWIELLHYLDLETTWLNTLEERMKSTEVL
                     PEKTDAVNEALESLESVLRHPADNRTQIRELGQTLIDGGILDDIISEKLEAFNSRYED
                     LSHLAESKQISLEKQLQVLRETDQMLQVLQESLGELDKQLTTYLTDRIDAFQVPQEAQ
                     KIQAEISAHELTLEELRRNMRSQPLTSPESRTARGGSQMDVLQRKLREVSTKFQLFQK
                     PANFEQRMLDCKRVLDGVKAELHVLDVKDVDPDVIQTHLDKCMKLYKTLSEVKLEVET
                     VIKTGRHIVQKQQTDNPKGMDEQLTSLKVLYNDLGAQVTEGKQDLERASQLARKMKKE
                     AASLSEWLSATETELVQKSTSEGLLGDLDTEISWAKNVLKDLEKRKADLNTITESSAA
                     LQNLIEGSEPILEERLCVLNAGWSRVRTWTEDWCNTLMNHQNQLEIFDGNVAHISTWL
                     YQAEALLDEIEKKPTSKQEEIVKRLVSELDDANLQVENVRDQALILMNARGSSSRELV
                     EPKLAELNRNFEKVSQHIKSAKLLIAQEPLYQCLVTTETFETGVPFSDLEKLENDIEN
                     MLKFVEKHLESSDEDEKMDEESAQIEEVLQRGEEMLHQPMEDNKKEKIRLQLLLLHTR
                     YNKIKAIPIQQRKMGQLASGIRSSLLPTDYLVEINKILLCMDDVELSLNVPELNTAIY
                     EDFSFQEDSLKNIKDQLDKLGEQIAVIHEKQPDVILEASGPEAIQIRDTLTQLNAKWD
                     RINRMYSDRKGCFDRAMEEWRQFHCDLNDLTQWITEAEELLVDTCAPGGSLDLEKARI
                     HQQELEVGISSHQPSFAALNRTGDGIVQKLSQADGSFLKEKLAGLNQRWDAIVAEVKD
                     RQPRLKGESKQVMKYRHQLDEIICWLTKAEHAMQKRSTTELGENLQELRDLTQEMEVH
                     AEKLKWLNRTELEMLSDKSLSLPERDKISESLRTVNMTWNKICREVPTTLKECIQEPS
                     SVSQTRIAAHPNVQKVVLVSSASDIPVQSHRTSEISIPADLDKTITELADWLVLIDQM
                     LKSNIVTVGDVEEINKTVSRMKITKADLEQRHPQLDYVFTLAQNLKNKASSSDMRTAI
                     TEKLERVKNQWDGTQHGVELRQQQLEDMIIDSLQWDDHREETEELMRKYEARLYILQQ
                     ARRDPLTKQISDNQILLQELGPGDGIVMAFDNVLQKLLEEYGSDDTRNVKETTEYLKT
                     SWINLKQSIADRQNALEAEWRTVQASRRDLENFLKWIQEAETTVNVLVDASHRENALQ
                     DSILARELKQQMQDIQAEIDAHNDIFKSIDGNRQKMVKALGNSEEATMLQHRLDDMNQ
                     RWNDLKAKSASIRAHLEASAEKWNRLLMSLEELIKWLNMKDEELKKQMPIGGDVPALQ
                     LQYDHCKALRRELKEKEYSVLNAVDQARVFLADQPIEAPEEPRRNLQSKTELTPEERA
                     QKIAKAMRKQSSEVKEKWESLNAVTSNWQKQVDKALEKLRDLQGAMDDLDADMKEAES
                     VRNGWKPVGDLLIDSLQDHIEKIMAFREEIAPINFKVKTVNDLSSQLSPLDLHPSLKM
                     SRQLDDLNMRWKLLQVSVDDRLKQLQEAHRDFGPSSQHFLSTSVQLPWQRSISHNKVP
                     YYINHQTQTTCWDHPKMTELFQSLADLNNVRFSAYRTAIKIRRLQKALCLDLLELSTT
                     NEIFKQHKLNQNDQLLSVPDVINCLTTTYDGLEQMHKDLVNVPLCVDMCLNWLLNVYD
                     TGRTGKIRVQSLKIGLMSLSKGLLEEKYRYLFKEVAGPTEMCDQRQLGLLLHDAIQIP
                     RQLGEVAAFGGSNIEPSVRSCFQQNNNKPEISVKEFIDWMHLEPQSMVWLPVLHRVAA
                     AETAKHQAKCNICKECPIVGFRYRSLKHFNYDVCQSCFFSGRTAKGHKLHYPMVEYCI
                     PTTSGEDVRDFTKVLKNKFRSKKYFAKHPRLGYLPVQTVLEGDNLETPITLISMWPEH
                     YDPSQSPQLFHDDTHSRIEQYATRLAQMERTNGSFLTDSSSTTGSVEDEHALIQQYCQ
                     TLGGESPVSQPQSPAQILKSVEREERGELERIIADLEEEQRNLQVEYEQLKDQHLRRG
                     LPVGSPPESIISPHHTSEDSELIAEAKLLRQHKGRLEARMQILEDHNKQLESQLHRLR
                     QLLEQPESDSRINGVSPWASPQHSALSYSLDPDASGPQFHQAAGEDLLAPPHDTSTDL
                     TEVMEQIHSTFPSCCPNVPSRPQAM"
     exon            659..720
                     /gene="UTRN"
                     /gene_synonym="DMDL; DRP; DRP1"
                     /inference="alignment:Splign:2.1.0"
     exon            721..813
                     /gene="UTRN"
                     /gene_synonym="DMDL; DRP; DRP1"
                     /inference="alignment:Splign:2.1.0"
     exon            814..891
                     /gene="UTRN"
                     /gene_synonym="DMDL; DRP; DRP1"
                     /inference="alignment:Splign:2.1.0"
     exon            892..984
                     /gene="UTRN"
                     /gene_synonym="DMDL; DRP; DRP1"
                     /inference="alignment:Splign:2.1.0"
     exon            985..1157
                     /gene="UTRN"
                     /gene_synonym="DMDL; DRP; DRP1"
                     /inference="alignment:Splign:2.1.0"
     exon            1158..1273
                     /gene="UTRN"
                     /gene_synonym="DMDL; DRP; DRP1"
                     /inference="alignment:Splign:2.1.0"
     exon            1274..1434
                     /gene="UTRN"
                     /gene_synonym="DMDL; DRP; DRP1"
                     /inference="alignment:Splign:2.1.0"
     exon            1435..1638
                     /gene="UTRN"
                     /gene_synonym="DMDL; DRP; DRP1"
                     /inference="alignment:Splign:2.1.0"
     exon            1639..1820
                     /gene="UTRN"
                     /gene_synonym="DMDL; DRP; DRP1"
                     /inference="alignment:Splign:2.1.0"
     exon            1821..1971
                     /gene="UTRN"
                     /gene_synonym="DMDL; DRP; DRP1"
                     /inference="alignment:Splign:2.1.0"
     exon            1972..2091
                     /gene="UTRN"
                     /gene_synonym="DMDL; DRP; DRP1"
                     /inference="alignment:Splign:2.1.0"
     exon            2092..2193
                     /gene="UTRN"
                     /gene_synonym="DMDL; DRP; DRP1"
                     /inference="alignment:Splign:2.1.0"
     exon            2194..2301
                     /gene="UTRN"
                     /gene_synonym="DMDL; DRP; DRP1"
                     /inference="alignment:Splign:2.1.0"
     exon            2302..2481
                     /gene="UTRN"
                     /gene_synonym="DMDL; DRP; DRP1"
                     /inference="alignment:Splign:2.1.0"
     exon            2482..2651
                     /gene="UTRN"
                     /gene_synonym="DMDL; DRP; DRP1"
                     /inference="alignment:Splign:2.1.0"
     exon            2652..2775
                     /gene="UTRN"
                     /gene_synonym="DMDL; DRP; DRP1"
                     /inference="alignment:Splign:2.1.0"
     exon            2776..2863
                     /gene="UTRN"
                     /gene_synonym="DMDL; DRP; DRP1"
                     /inference="alignment:Splign:2.1.0"
     exon            2864..3105
                     /gene="UTRN"
                     /gene_synonym="DMDL; DRP; DRP1"
                     /inference="alignment:Splign:2.1.0"
     exon            3106..3286
                     /gene="UTRN"
                     /gene_synonym="DMDL; DRP; DRP1"
                     /inference="alignment:Splign:2.1.0"
     exon            3287..3432
                     /gene="UTRN"
                     /gene_synonym="DMDL; DRP; DRP1"
                     /inference="alignment:Splign:2.1.0"
     exon            3433..3645
                     /gene="UTRN"
                     /gene_synonym="DMDL; DRP; DRP1"
                     /inference="alignment:Splign:2.1.0"
     exon            3646..3759
                     /gene="UTRN"
                     /gene_synonym="DMDL; DRP; DRP1"
                     /inference="alignment:Splign:2.1.0"
     exon            3760..3915
                     /gene="UTRN"
                     /gene_synonym="DMDL; DRP; DRP1"
                     /inference="alignment:Splign:2.1.0"
     exon            3916..4086
                     /gene="UTRN"
                     /gene_synonym="DMDL; DRP; DRP1"
                     /inference="alignment:Splign:2.1.0"
     exon            4087..4266
                     /gene="UTRN"
                     /gene_synonym="DMDL; DRP; DRP1"
                     /inference="alignment:Splign:2.1.0"
     exon            4267..4401
                     /gene="UTRN"
                     /gene_synonym="DMDL; DRP; DRP1"
                     /inference="alignment:Splign:2.1.0"
     exon            4402..4551
                     /gene="UTRN"
                     /gene_synonym="DMDL; DRP; DRP1"
                     /inference="alignment:Splign:2.1.0"
     exon            4552..4713
                     /gene="UTRN"
                     /gene_synonym="DMDL; DRP; DRP1"
                     /inference="alignment:Splign:2.1.0"
     exon            4714..4842
                     /gene="UTRN"
                     /gene_synonym="DMDL; DRP; DRP1"
                     /inference="alignment:Splign:2.1.0"
     exon            4843..5016
                     /gene="UTRN"
                     /gene_synonym="DMDL; DRP; DRP1"
                     /inference="alignment:Splign:2.1.0"
     exon            5017..5172
                     /gene="UTRN"
                     /gene_synonym="DMDL; DRP; DRP1"
                     /inference="alignment:Splign:2.1.0"
     exon            5173..5343
                     /gene="UTRN"
                     /gene_synonym="DMDL; DRP; DRP1"
                     /inference="alignment:Splign:2.1.0"
     exon            5344..5523
                     /gene="UTRN"
                     /gene_synonym="DMDL; DRP; DRP1"
                     /inference="alignment:Splign:2.1.0"
     exon            5524..5652
                     /gene="UTRN"
                     /gene_synonym="DMDL; DRP; DRP1"
                     /inference="alignment:Splign:2.1.0"
     exon            5653..5823
                     /gene="UTRN"
                     /gene_synonym="DMDL; DRP; DRP1"
                     /inference="alignment:Splign:2.1.0"
     exon            5824..5982
                     /gene="UTRN"
                     /gene_synonym="DMDL; DRP; DRP1"
                     /inference="alignment:Splign:2.1.0"
     exon            5983..6120
                     /gene="UTRN"
                     /gene_synonym="DMDL; DRP; DRP1"
                     /inference="alignment:Splign:2.1.0"
     exon            6121..6312
                     /gene="UTRN"
                     /gene_synonym="DMDL; DRP; DRP1"
                     /inference="alignment:Splign:2.1.0"
     exon            6313..6485
                     /gene="UTRN"
                     /gene_synonym="DMDL; DRP; DRP1"
                     /inference="alignment:Splign:2.1.0"
     exon            6486..6636
                     /gene="UTRN"
                     /gene_synonym="DMDL; DRP; DRP1"
                     /inference="alignment:Splign:2.1.0"
     exon            6637..6812
                     /gene="UTRN"
                     /gene_synonym="DMDL; DRP; DRP1"
                     /inference="alignment:Splign:2.1.0"
     exon            6813..6948
                     /gene="UTRN"
                     /gene_synonym="DMDL; DRP; DRP1"
                     /inference="alignment:Splign:2.1.0"
     exon            6949..7098
                     /gene="UTRN"
                     /gene_synonym="DMDL; DRP; DRP1"
                     /inference="alignment:Splign:2.1.0"
     exon            7099..7174
                     /gene="UTRN"
                     /gene_synonym="DMDL; DRP; DRP1"
                     /inference="alignment:Splign:2.1.0"
     exon            7175..7389
                     /gene="UTRN"
                     /gene_synonym="DMDL; DRP; DRP1"
                     /inference="alignment:Splign:2.1.0"
     exon            7390..7507
                     /gene="UTRN"
                     /gene_synonym="DMDL; DRP; DRP1"
                     /inference="alignment:Splign:2.1.0"
     exon            7508..7713
                     /gene="UTRN"
                     /gene_synonym="DMDL; DRP; DRP1"
                     /inference="alignment:Splign:2.1.0"
     exon            7714..7868
                     /gene="UTRN"
                     /gene_synonym="DMDL; DRP; DRP1"
                     /inference="alignment:Splign:2.1.0"
     exon            7869..8058
                     /gene="UTRN"
                     /gene_synonym="DMDL; DRP; DRP1"
                     /inference="alignment:Splign:2.1.0"
     exon            8059..8231
                     /gene="UTRN"
                     /gene_synonym="DMDL; DRP; DRP1"
                     /inference="alignment:Splign:2.1.0"
     exon            8232..8388
                     /gene="UTRN"
                     /gene_synonym="DMDL; DRP; DRP1"
                     /inference="alignment:Splign:2.1.0"
     exon            8389..8518
                     /gene="UTRN"
                     /gene_synonym="DMDL; DRP; DRP1"
                     /inference="alignment:Splign:2.1.0"
     exon            8519..8787
                     /gene="UTRN"
                     /gene_synonym="DMDL; DRP; DRP1"
                     /inference="alignment:Splign:2.1.0"
     exon            8788..8934
                     /gene="UTRN"
                     /gene_synonym="DMDL; DRP; DRP1"
                     /inference="alignment:Splign:2.1.0"
     exon            8935..9013
                     /gene="UTRN"
                     /gene_synonym="DMDL; DRP; DRP1"
                     /inference="alignment:Splign:2.1.0"
     exon            9014..9074
                     /gene="UTRN"
                     /gene_synonym="DMDL; DRP; DRP1"
                     /inference="alignment:Splign:2.1.0"
     exon            9075..9136
                     /gene="UTRN"
                     /gene_synonym="DMDL; DRP; DRP1"
                     /inference="alignment:Splign:2.1.0"
     exon            9137..9211
                     /gene="UTRN"
                     /gene_synonym="DMDL; DRP; DRP1"
                     /inference="alignment:Splign:2.1.0"
     exon            9212..9413
                     /gene="UTRN"
                     /gene_synonym="DMDL; DRP; DRP1"
                     /inference="alignment:Splign:2.1.0"
     exon            9414..9499
                     /gene="UTRN"
                     /gene_synonym="DMDL; DRP; DRP1"
                     /inference="alignment:Splign:2.1.0"
     exon            9500..9657
                     /gene="UTRN"
                     /gene_synonym="DMDL; DRP; DRP1"
                     /inference="alignment:Splign:2.1.0"
     exon            9658..9824
                     /gene="UTRN"
                     /gene_synonym="DMDL; DRP; DRP1"
                     /inference="alignment:Splign:2.1.0"
     exon            9825..9936
                     /gene="UTRN"
                     /gene_synonym="DMDL; DRP; DRP1"
                     /inference="alignment:Splign:2.1.0"
     exon            9937..10073
                     /gene="UTRN"
                     /gene_synonym="DMDL; DRP; DRP1"
                     /inference="alignment:Splign:2.1.0"
     exon            10074..10112
                     /gene="UTRN"
                     /gene_synonym="DMDL; DRP; DRP1"
                     /inference="alignment:Splign:2.1.0"
     exon            10113..10178
                     /gene="UTRN"
                     /gene_synonym="DMDL; DRP; DRP1"
                     /inference="alignment:Splign:2.1.0"
     exon            10179..10244
                     /gene="UTRN"
                     /gene_synonym="DMDL; DRP; DRP1"
                     /inference="alignment:Splign:2.1.0"
     exon            10245..10403
                     /gene="UTRN"
                     /gene_synonym="DMDL; DRP; DRP1"
                     /inference="alignment:Splign:2.1.0"
     exon            10404..10644
                     /gene="UTRN"
                     /gene_synonym="DMDL; DRP; DRP1"
                     /inference="alignment:Splign:2.1.0"
     exon            10645..10756
                     /gene="UTRN"
                     /gene_synonym="DMDL; DRP; DRP1"
                     /inference="alignment:Splign:2.1.0"
     exon            10757..10849
                     /gene="UTRN"
                     /gene_synonym="DMDL; DRP; DRP1"
                     /inference="alignment:Splign:2.1.0"
     exon            10850..10872
                     /gene="UTRN"
                     /gene_synonym="DMDL; DRP; DRP1"
                     /inference="alignment:Splign:2.1.0"
     exon            10873..12918
                     /gene="UTRN"
                     /gene_synonym="DMDL; DRP; DRP1"
                     /inference="alignment:Splign:2.1.0"
     regulatory      12781..12786
                     /regulatory_class="polyA_signal_sequence"
                     /gene="UTRN"
                     /gene_synonym="DMDL; DRP; DRP1"
                     /note="hexamer: AAGAAA"
     regulatory      12785..12790
                     /regulatory_class="polyA_signal_sequence"
                     /gene="UTRN"
                     /gene_synonym="DMDL; DRP; DRP1"
                     /note="hexamer: AATATA"
     polyA_site      12799
                     /gene="UTRN"
                     /gene_synonym="DMDL; DRP; DRP1"
     polyA_site      12802
                     /gene="UTRN"
                     /gene_synonym="DMDL; DRP; DRP1"
     regulatory      12897..12902
                     /regulatory_class="polyA_signal_sequence"
                     /gene="UTRN"
                     /gene_synonym="DMDL; DRP; DRP1"
                     /note="hexamer: AATAAA"
     polyA_site      12918
                     /gene="UTRN"
                     /gene_synonym="DMDL; DRP; DRP1"
                     /note="major polyA site"
ORIGIN      
        1 gtttttcctc ggagcaggga agcgggcagc agcagccggc cgcgggcttt ctcccgccga
       61 ggggcgagga ggagcctctg gctccagaag ccgattgggg aatcacgggg agcggcgccc
      121 cccttctttt gggtcatttc tgcaaacgga aaactctgta gcgtttggca aagttggtgc
      181 ctgcgcgccc cttccaggtt tgcgctttga ctgttttgtt tttggcggaa ctaccaggca
      241 ggaagattgc acaagtaagg ggcgttttca gtcgggtgtc aatttctctt tctttctttc
      301 tttttttaaa atttcggttc gtgtctgctt ctccaagctt tatttttttt tttaaataca
      361 tcgcaccacc aaactaacac tcgcacacac ccccgcggtt actccgtgtc aaactcctag
      421 aggagccctt ggccagctcg gggtgcggcg gtggcgaccg gcaggcgagg aggcccgcgg
      481 gcagcaggta ttgatgtcaa gctgaaccat cgtaggaagt tgaaagcctt agaaagagga
      541 cttggtaaag tttttggatt atcttgaaac tctggcaaga tggccaagta tggagaacat
      601 gaagccagtc ctgacaatgg gcagaacgaa ttcagtgata tcattaagtc cagatctgat
      661 gaacacaatg acgtacagaa gaaaaccttt accaaatgga taaatgctcg attttcaaag
      721 agtgggaaac cacccatcaa tgatatgttc acagacctca aagatggaag gaagctattg
      781 gatcttctag aaggcctcac aggaacatca ctgccaaagg aacgtggttc cacaagggta
      841 catgccttaa ataacgtcaa cagagtgctg caggttttac atcagaacaa tgtggaatta
      901 gtgaatatag ggggaactga cattgtggat ggaaatcaca aactgacttt ggggttactt
      961 tggagcatca ttttgcactg gcaggtgaaa gatgtcatga aggatgtcat gtcggacctg
     1021 cagcagacga acagtgagaa gatcctgctc agctgggtgc gtcagaccac caggccctac
     1081 agccaagtca acgtcctcaa cttcaccacc agctggacag atggactcgc ctttaatgct
     1141 gtcctccacc gacataaacc tgatctcttc agctgggata aagttgtcaa aatgtcacca
     1201 attgagagac ttgaacatgc cttcagcaag gctcaaactt atttgggaat tgaaaagctg
     1261 ttagatcctg aagatgttgc cgttcagctt cctgacaaga aatccataat tatgtattta
     1321 acatctttgt ttgaggtgct acctcagcaa gtcaccatag acgccatccg tgaggtagag
     1381 acactcccaa ggaaatataa aaaagaatgt gaagaagagg caattaatat acagagtaca
     1441 gcgcctgagg aggagcatga gagtccccga gctgaaactc ccagcactgt cactgaggtt
     1501 gacatggatc tggacagcta tcagattgcg ttggaggaag tgctgacctg gttgctttct
     1561 gctgaggaca ctttccagga gcaggatgat atttctgatg atgttgaaga agtcaaagac
     1621 cagtttgcaa cccatgaagc ttttatgatg gaactgactg cacaccagag cagtgtgggc
     1681 agcgtcctgc aggcaggcaa ccaactgata acacaaggaa ctctgtcaga cgaagaagaa
     1741 tttgagattc aggaacagat gaccctgctg aatgctagat gggaggctct tagggtggag
     1801 agtatggaca gacagtcccg gctgcacgat gtgctgatgg aactgcagaa gaagcaactg
     1861 cagcagctct ccgcctggtt aacactcaca gaggagcgca ttcagaagat ggaaacttgc
     1921 cccctggatg atgatgtaaa atctctacaa aagctgctag aagaacataa aagtttgcaa
     1981 agtgatcttg aggctgaaca ggtgaaagta aattcactaa ctcacatggt ggtcattgtt
     2041 gatgaaaaca gtggtgagag tgctacagct atcctagaag accagttaca gaaacttggt
     2101 gagcgctgga cagcagtatg ccgttggact gaagaacgct ggaataggtt acaagaaatc
     2161 aatatattgt ggcaggaatt attggaagaa cagtgcttgt tgaaagcttg gttaaccgaa
     2221 aaagaagagg ctttaaataa agtccagaca agcaacttca aagaccaaaa ggaactaagt
     2281 gtcagtgttc gacgtctggc tattttgaag gaagacatgg aaatgaagcg tcaaacattg
     2341 gatcagctga gtgagattgg ccaggatgtg ggacaattac ttgataattc caaggcatct
     2401 aagaagatca acagtgactc agaggaactg actcaaagat gggattcttt ggttcagaga
     2461 ctagaagatt cctccaacca ggtgactcag gctgtagcaa agctggggat gtctcagatt
     2521 cctcagaagg accttttgga gactgttcgt gtaagagaac aagcaattac aaaaaaatct
     2581 aagcaggaac tgcctcctcc tcctccccca aagaagagac agatccatgt ggatattgaa
     2641 gctaagaaaa agtttgatgc tataagtgca gagctgttga actggatttt gaaatggaaa
     2701 actgccattc agaccacaga gataaaagag tatatgaaga tgcaagacac ttccgaaatg
     2761 aaaaagaagt tgaaggcatt agaaaaagaa cagagagaaa gaatccccag agcagatgaa
     2821 ttaaaccaaa ctggacaaat ccttgtggag caaatgggaa aagaaggcct tcctactgaa
     2881 gaaataaaaa atgttctgga gaaggtttca tcagaatgga agaatgtatc tcaacatttg
     2941 gaagatctag aaagaaagat tcagctacag gaagatataa atgcttattt caagcagctt
     3001 gatgagcttg aaaaggtcat caagacaaag gaggagtggg taaaacacac ttccatttct
     3061 gaatcttccc ggcagtcctt gccaagcttg aaggattcct gtcagcggga attgacaaat
     3121 cttcttggcc ttcaccccaa aattgaaatg gctcgtgcaa gctgctcggc cctgatgtct
     3181 cagccttctg ccccagattt tgtccagcgg ggcttcgata gctttctggg ccgctaccaa
     3241 gctgtacaag aggctgtaga ggatcgtcaa caacatctag agaatgaact gaagggccaa
     3301 cctggacatg catatctgga aacattgaaa acactgaaag atgtgctaaa tgattcagaa
     3361 aataaggccc aggtgtctct gaatgtcctt aatgatcttg ccaaggtgga gaaggccctg
     3421 caagaaaaaa agacccttga tgaaatcctt gagaatcaga aacctgcatt acataaactt
     3481 gcagaagaaa caaaggctct ggagaaaaat gttcatcctg atgtagaaaa attatataag
     3541 caagaatttg atgatgtgca aggaaagtgg aacaagctaa aggtcttggt ttccaaagat
     3601 ctacatttgc ttgaggaaat tgctctcaca ctcagagctt ttgaggccga ttcaacagtc
     3661 attgagaagt ggatggatgg cgtgaaagac ttcttaatga aacagcaggc tgcccaagga
     3721 gacgacgcag gtctacagag gcagttagac cagtgctctg catttgttaa tgaaatagaa
     3781 acaattgaat catctctgaa aaacatgaag gaaatagaga ctaatcttcg aagtggtcca
     3841 gttgctggaa taaaaacttg ggtgcagaca agactaggtg actaccaaac tcaactggag
     3901 aaacttagca aggagatcgc tactcaaaaa agtaggttgt ctgaaagtca agaaaaagct
     3961 gcgaacctga agaaagactt ggcagagatg caggaatgga tgacccaggc cgaggaagaa
     4021 tatttggagc gggattttga gtacaagtca ccagaagagc ttgagagtgc tgtggaagag
     4081 atgaagaggg caaaagagga tgtgttgcag aaggaggtga gagtgaagat tctcaaggac
     4141 aacatcaagt tattagctgc caaggtgccc tctggtggcc aggagttgac gtctgagctg
     4201 aatgttgtgc tggagaatta ccaacttctt tgtaatagaa ttcgaggaaa gtgccacacg
     4261 ctagaggagg tctggtcttg ttggattgaa ctgcttcact atttggatct tgaaactacc
     4321 tggttaaaca ctttggaaga gcggatgaag agcacagagg tcctgcctga gaagacggat
     4381 gctgtcaacg aagccctgga gtctctggaa tctgttctgc gccacccggc agataatcgc
     4441 acccagattc gagagcttgg ccagactctg attgatgggg ggatcctgga tgatataatc
     4501 agtgagaaac tggaggcttt caacagccga tatgaagatc taagtcacct ggcagagagc
     4561 aagcagattt ctttggaaaa gcaactccag gtgctgcggg aaactgacca gatgcttcaa
     4621 gtcttgcaag agagcttggg ggagctggac aaacagctca ccacatacct gactgacagg
     4681 atagatgctt tccaagttcc acaggaagct cagaaaatcc aagcagagat ctcagcccat
     4741 gagctaaccc tagaggagtt gagaagaaat atgcgttctc agcccctgac ctccccagag
     4801 agtaggactg ccagaggagg aagtcagatg gatgtgctac agaggaaact ccgagaggtg
     4861 tccacaaagt tccagctttt ccagaagcca gctaacttcg agcagcgcat gctggactgc
     4921 aagcgtgtgc tggatggcgt gaaagcagaa cttcacgttc tggatgtgaa ggacgtagac
     4981 cctgacgtca tacagacgca cctggacaag tgtatgaaac tgtataaaac tttgagtgaa
     5041 gtcaaacttg aagtggaaac tgtgattaaa acaggaagac atattgtcca gaaacagcaa
     5101 acggacaacc caaaagggat ggatgagcag ctgacttccc tgaaggttct ttacaatgac
     5161 ctgggcgcac aggtgacaga aggaaaacag gatctggaaa gagcatcaca gttggcccgg
     5221 aaaatgaaga aagaggctgc ttctctctct gaatggcttt ctgctactga aactgaattg
     5281 gtacagaagt ccacttcaga aggtctgctt ggtgacttgg atacagaaat ttcctgggct
     5341 aaaaatgttc tgaaggatct ggaaaagaga aaagctgatt taaataccat cacagagagt
     5401 agtgctgccc tgcaaaactt gattgagggc agtgagccta ttttagaaga gaggctctgc
     5461 gtccttaacg ctgggtggag ccgagttcgt acctggactg aagattggtg caataccttg
     5521 atgaaccatc agaaccagct agaaatattt gatgggaacg tggctcacat aagtacctgg
     5581 ctttatcaag ctgaagctct attggatgaa attgaaaaga aaccaacaag taaacaggaa
     5641 gaaattgtga agcgtttagt atctgagctg gatgatgcca acctccaggt tgaaaatgtc
     5701 cgcgatcaag cccttatttt gatgaatgcc cgtggaagct caagcaggga gcttgtagaa
     5761 ccaaagttag ctgagctgaa taggaacttt gaaaaggtgt ctcaacatat caaaagtgcc
     5821 aaattgctaa ttgctcagga accattatac caatgtttgg tcaccactga aacatttgaa
     5881 actggtgtgc ctttctctga cttggaaaaa ttagaaaatg acatagaaaa tatgttaaaa
     5941 tttgtggaaa aacacttgga atccagtgat gaagatgaaa agatggatga ggagagtgcc
     6001 cagattgagg aagttctaca aagaggagaa gaaatgttac atcaacctat ggaagataat
     6061 aaaaaagaaa agatccgttt gcaattatta cttttgcata ctagatacaa caaaattaag
     6121 gcaatcccta ttcaacagag gaaaatgggt caacttgctt ctggaattag atcatcactt
     6181 cttcctacag attatctggt tgaaattaac aaaattttac tttgcatgga tgatgttgaa
     6241 ttatcgctta atgttccaga gctcaacact gctatttacg aagacttctc ttttcaggaa
     6301 gactctctga agaatatcaa agaccaactg gacaaacttg gagagcagat tgcagtcatt
     6361 catgaaaaac agccagatgt catccttgaa gcctctggac ctgaagccat tcagatcaga
     6421 gatacactta ctcagctgaa tgcaaaatgg gacagaatta atagaatgta cagtgatcgg
     6481 aaaggttgtt ttgacagggc aatggaagaa tggagacagt tccattgtga ccttaatgac
     6541 ctcacacagt ggataacaga ggctgaagaa ttactggttg atacctgtgc tccaggtggc
     6601 agcctggact tagagaaagc caggatacat cagcaggaac ttgaggtggg catcagcagc
     6661 caccagccca gttttgcagc actaaaccga actggggatg ggattgtgca gaaactctcc
     6721 caggcagatg gaagcttctt gaaagaaaaa ctggcaggtt taaaccaacg ctgggatgca
     6781 attgttgcag aagtgaagga taggcagcca aggctaaaag gagaaagtaa gcaggtgatg
     6841 aagtacaggc atcagctaga tgagattatc tgttggttaa caaaggctga gcatgctatg
     6901 caaaagagat caaccaccga attgggagaa aacctgcaag aattaagaga cttaactcaa
     6961 gaaatggaag tacatgctga aaaactcaaa tggctgaata gaactgaatt ggagatgctt
     7021 tcagataaaa gtctgagttt acctgaaagg gataaaattt cagaaagctt aaggactgta
     7081 aatatgacat ggaataagat ttgcagagag gtgcctacca ccctgaagga atgcatccag
     7141 gagcccagtt ctgtttcaca gacaaggatt gctgctcatc ctaatgtcca aaaggtggtg
     7201 ctagtatcat ctgcgtcaga tattcctgtt cagtctcatc gtacttcgga aatttcaatt
     7261 cctgctgatc ttgataaaac tataacagaa ctagccgact ggctggtatt aatcgaccag
     7321 atgctgaagt ccaacattgt cactgttggg gatgtagaag agatcaataa gaccgtttcc
     7381 cgaatgaaaa ttacaaaggc tgacttagaa cagcgccatc ctcagctgga ttatgttttt
     7441 acattggcac agaatttgaa aaataaagct tccagttcag atatgagaac agcaattaca
     7501 gaaaaattgg aaagggtcaa gaaccagtgg gatggcaccc agcatggcgt tgagctaaga
     7561 cagcagcagc ttgaggacat gattattgac agtcttcagt gggatgacca tagggaggag
     7621 actgaagaac tgatgagaaa atatgaggct cgactctata ttcttcagca agcccgacgg
     7681 gatccactca ccaaacaaat ttctgataac caaatactgc ttcaagaact gggtcctgga
     7741 gatggtatcg tcatggcgtt cgataacgtc ctgcagaaac tcctggagga atatgggagt
     7801 gatgacacaa ggaatgtgaa agaaaccaca gagtacttaa aaacatcatg gatcaatctc
     7861 aaacaaagta ttgctgacag acagaacgcc ttggaggctg agtggaggac ggtgcaggcc
     7921 tctcgcagag atctggaaaa cttcctgaag tggatccaag aagcagagac cacagtgaat
     7981 gtgcttgtgg atgcctctca tcgggagaat gctcttcagg atagtatctt ggccagggaa
     8041 ctcaaacagc agatgcagga catccaggca gaaattgatg cccacaatga catatttaaa
     8101 agcattgacg gaaacaggca gaagatggta aaagctttgg gaaattctga agaggctact
     8161 atgcttcaac atcgactgga tgatatgaac caaagatgga atgacttaaa agcaaaatct
     8221 gctagcatca gggcccattt ggaggccagc gctgagaagt ggaacaggtt gctgatgtcc
     8281 ttagaagaac tgatcaaatg gctgaatatg aaagatgaag agcttaagaa acaaatgcct
     8341 attggaggag atgttccagc cttacagctc cagtatgacc attgtaaggc cctgagacgg
     8401 gagttaaagg agaaagaata ttctgtcctg aatgctgtcg accaggcccg agttttcttg
     8461 gctgatcagc caattgaggc ccctgaagag ccaagaagaa acctacaatc aaaaacagaa
     8521 ttaactcctg aggagagagc ccaaaagatt gccaaagcca tgcgcaaaca gtcttctgaa
     8581 gtcaaagaaa aatgggaaag tctaaatgct gtaactagca attggcaaaa gcaagtggac
     8641 aaggcattgg agaaactcag agacctgcag ggagctatgg atgacctgga cgctgacatg
     8701 aaggaggcag agtccgtgcg gaatggctgg aagcccgtgg gagacttact cattgactcg
     8761 ctgcaggatc acattgaaaa aatcatggca tttagagaag aaattgcacc aatcaacttt
     8821 aaagttaaaa cggtgaatga tttatccagt cagctgtctc cacttgacct gcatccctct
     8881 ctaaagatgt ctcgccagct agatgacctt aatatgcgat ggaaactttt acaggtttct
     8941 gtggatgatc gccttaaaca gcttcaggaa gcccacagag attttggacc atcctctcag
     9001 cattttctct ctacgtcagt ccagctgccg tggcaaagat ccatttcaca taataaagtg
     9061 ccctattaca tcaaccatca aacacagacc acctgttggg accatcctaa aatgaccgaa
     9121 ctctttcaat cccttgctga cctgaataat gtacgttttt ctgcctaccg tacagcaatc
     9181 aaaatccgaa gactacaaaa agcactatgt ttggatctct tagagttgag tacaacaaat
     9241 gaaattttca aacagcacaa gttgaaccaa aatgaccagc tcctcagtgt tccagatgtc
     9301 atcaactgtc tgacaacaac ttatgatgga cttgagcaaa tgcataagga cctggtcaac
     9361 gttccactct gtgttgatat gtgtctcaat tggttgctca atgtctatga cacgggtcga
     9421 actggaaaaa ttagagtgca gagtctgaag attggattaa tgtctctctc caaaggtctc
     9481 ttggaagaaa aatacagata tctctttaag gaagttgcag ggccaacaga aatgtgtgac
     9541 cagaggcagc tgggcctgtt acttcatgat gccatccaga tcccccggca gctaggtgaa
     9601 gtagcagctt ttggaggcag taatattgag cctagtgttc gcagctgctt ccaacagaat
     9661 aacaataaac cagaaataag tgtgaaagag tttatagatt ggatgcattt ggaaccacag
     9721 tccatggttt ggctcccagt tttacatcga gtggcagcag cggagactgc aaaacatcag
     9781 gccaaatgca acatctgtaa agaatgtcca attgtcgggt tcaggtatag aagccttaag
     9841 cattttaact atgatgtctg ccagagttgt ttcttttcgg gtcgaacagc aaaaggtcac
     9901 aaattacatt acccaatggt ggaatattgt atacctacaa catctgggga agatgtacga
     9961 gacttcacaa aggtacttaa gaacaagttc aggtcgaaga agtactttgc caaacaccct
    10021 cgacttggtt acctgcctgt ccagacagtt cttgaaggtg acaacttaga gactcctatc
    10081 acactcatca gtatgtggcc agagcactat gacccctcac aatctcctca actgtttcat
    10141 gatgacaccc attcaagaat agaacaatat gccacacgac tggcccagat ggaaaggact
    10201 aatgggtctt ttctcactga tagcagctcc accacaggaa gtgtggaaga cgagcacgcc
    10261 ctcatccagc agtattgcca aacactcgga ggagagtccc cagtgagcca gccgcagagc
    10321 ccagctcaga tcctgaagtc agtagagagg gaagaacgtg gagaactgga gaggatcatt
    10381 gctgacctgg aggaagaaca aagaaatcta caggtggagt atgagcagct gaaggaccag
    10441 cacctccgaa gggggctccc tgtcggttca ccgccagagt cgattatatc tccccatcac
    10501 acgtctgagg attcagaact tatagcagaa gcaaaactcc tcaggcagca caaaggtcgg
    10561 ctggaggcta ggatgcagat tttagaagat cacaataaac agctggagtc tcagctccac
    10621 cgcctccgac agctgctgga gcagcctgaa tctgattccc gaatcaatgg tgtttcccca
    10681 tgggcttctc ctcagcattc tgcactgagc tactcgcttg atccagatgc ctccggccca
    10741 cagttccacc aggcagcggg agaggacctg ctggccccac cgcacgacac cagcacggat
    10801 ctcacggagg tcatggagca gattcacagc acgtttccat cttgctgccc aaatgttccc
    10861 agcaggccac aggcaatgtg aagtattcat ccggccaacc aatgtttcct gacgtacagt
    10921 gttgcccttt tcagcaaatg ccaattccaa gttccattaa atcagaagct ccatggctcc
    10981 ttggcccacg atgttgagtg ctgactgtgt gttctactga aagagtaaaa cactgactat
    11041 ccaaagagaa atggatattt tgtttttata ataaccatat attattgttt tcttcttccc
    11101 tttctatgca agtgtaaatt aatgaacaga gaggtatttg gaaatggtaa tacatttgtc
    11161 acggatttgt ataatgtata cagcattggg aaagtgggtg ggggctttct aatatgatac
    11221 cgtcttttta ataactatga caaagcttac ataagaatta gaagaccact ttacattttt
    11281 acattccttc tgctgttcat attaaccttg cacaattact tcattttttc tttgactctt
    11341 ttaccacaat gttttggtta tttataattt atcagccata tgtttatcag ccatataacc
    11401 aactagatcc caaatagatc catgtatttg tttccgtgat ttggccacat taataaattc
    11461 ataaatttca atcaaatatc ttatatatac acacatatgg tttaagctac agccctgtgt
    11521 atgccgttta actttatttg acgttgccca cttacttctt tgctgaccac ttggataacc
    11581 gtaataaaaa tcctataagc ctaaatggca tttcttttgg gatatttttc ctgcatttta
    11641 ttcccttttt atataagtag gaattaatta tttattttat gtcttaatct atttgataaa
    11701 gaagactaca ttataataat ctcaaagatc atattaccaa aggttgccca cttgagcata
    11761 ttttcatttt gacacagaaa caaaatttag tacaaccttt cctagttccc atgtcttgat
    11821 tttcatcatt acatgcacag cagaccttta cctattgtga taccagaaca catcattgtc
    11881 tttggttccc ttcaaagaga attttattgt tgttttgtat tttcaagtcc ttaatagttc
    11941 ttgaaactcc tagttgtttt cttgttgaaa gcagacacac atttagtgca cggcttattt
    12001 tacctttcgg gtgaaagatc agatgttttt atacccttca cttgatcaat atatttggaa
    12061 agaatgttta tcaaaagtct atgtcactgc ttctacagaa gaatgaaatt aatgcttagg
    12121 tgatggtacc tccacctaca tctttttgag tgcattcaat tatgtatttt ggtttagctt
    12181 ctgatttaac atttaattga ttcagtttaa acatgttact taattagcaa atgtagagga
    12241 accaaaaaaa ggtgaaaata atatgttttg attcaaacct aaagacataa aaacataaag
    12301 acattttaac tttgggttct ctttagctgg gatctggcca gaaggaggct taaagttaga
    12361 aattgctatt attttagaat aggttgggtg ggttgggggg caagggtgtc tatttgcagc
    12421 agagatattt tgaaaagaag aaaattgttt tatataaaaa ggaaagccat gaccaccttt
    12481 ctacctcaga tccatcttca tccattgcat tggaaactgc tttatgctgc tgcagtctgc
    12541 aaagtctaga gcttttatca ggccatgtca tacccaagaa agcacctatt taaagaaaaa
    12601 acaattccct gagctctcaa ctccaagttg tagatttggt gtcttccttg ttcttacttt
    12661 aaaaagtcat gtgttaattt tttttctgcc tgtatttgta tgcaaaatgt cctctatctg
    12721 ctattaaaga aaagctacgt aaaacactac attgtaacct tctaagtaat aataaataaa
    12781 aagaaatata ttgcagtaac aatgggaagt aagtatgtag ttcttttgaa atatgtggta
    12841 aagaactaat cacagactat catctaatct ggttacatat tgtatttttc atcctgaata
    12901 aaagtaattt taacacaa
//
