LOCUS       NM_001089591             276 bp    mRNA    linear   PRI 22-SEP-2024
DEFINITION  Homo sapiens ubiquinol-cytochrome c reductase hinge protein like
            (UQCRHL), mRNA; nuclear gene for mitochondrial product.
ACCESSION   NM_001089591 XM_934930 XM_946277
VERSION     NM_001089591.2
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 276)
  AUTHORS   Morgenstern,M., Peikert,C.D., Lubbert,P., Suppanz,I., Klemm,C.,
            Alka,O., Steiert,C., Naumenko,N., Schendzielorz,A., Melchionda,L.,
            Muhlhauser,W.W.D., Knapp,B., Busch,J.D., Stiller,S.B.,
            Dannenmaier,S., Lindau,C., Licheva,M., Eickhorst,C., Galbusera,R.,
            Zerbes,R.M., Ryan,M.T., Kraft,C., Kozjak-Pavlovic,V., Drepper,F.,
            Dennerlein,S., Oeljeklaus,S., Pfanner,N., Wiedemann,N. and
            Warscheid,B.
  TITLE     Quantitative high-confidence human mitochondrial proteome and its
            dynamics in cellular context
  JOURNAL   Cell Metab 33 (12), 2464-2483 (2021)
   PUBMED   34800366
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL450998.19.
            
            On Aug 11, 2021 this sequence version replaced NM_001089591.1.
            
            Summary: This gene has characteristics of a pseudogene derived from
            the UQCRH gene. However, there is still an open reading frame that
            could produce a protein of the same or nearly the same size as that
            of the UQCRH gene, so this gene is being called protein-coding for
            now. [provided by RefSeq, Jul 2008].
            
            ##Evidence-Data-START##
            Transcript is intronless :: BX537499.1, CD675141.1 [ECO:0000345]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            gene product(s) localized to mito. :: inferred from homology
            MANE Ensembl match                 :: ENST00000696689.1/
                                                  ENSP00000512811.1
            RefSeq Select criteria             :: based on single
                                                  protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-276               AL450998.19        84610-84885         c
FEATURES             Location/Qualifiers
     source          1..276
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="1"
                     /map="1p36.21"
     gene            1..276
                     /gene="UQCRHL"
                     /gene_synonym="hCG25371"
                     /note="ubiquinol-cytochrome c reductase hinge protein
                     like"
                     /db_xref="GeneID:440567"
                     /db_xref="HGNC:HGNC:51714"
     CDS             1..276
                     /gene="UQCRHL"
                     /gene_synonym="hCG25371"
                     /codon_start=1
                     /product="cytochrome b-c1 complex subunit 6-like,
                     mitochondrial"
                     /protein_id="NP_001083060.1"
                     /db_xref="CCDS:CCDS76112.1"
                     /db_xref="GeneID:440567"
                     /db_xref="HGNC:HGNC:51714"
                     /translation="MGLEDEQKMLTESGDPEEEEEEEEELVDPLTTVREQCEQLEKCV
                     KARERLELYDEHVSSRSHTEEDCTEELFDFLHAKDHCVAHKLFNNLK"
     exon            1..276
                     /gene="UQCRHL"
                     /gene_synonym="hCG25371"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 atgggactgg aggacgagca aaagatgctt accgaatccg gagatcctga ggaggaggaa
       61 gaggaagagg aggaattagt ggatccccta acaacagtga gagagcaatg cgagcagttg
      121 gagaaatgtg taaaggcccg ggagcggcta gagctctatg atgagcatgt atcctctcga
      181 tcacatacag aagaggattg cacggaggag ctctttgact tcttgcatgc aaaggaccat
      241 tgcgtggccc acaaactctt taacaacttg aaataa
//
