LOCUS       NM_001272051             917 bp    mRNA    linear   PRI 20-SEP-2024
DEFINITION  Homo sapiens ubiquinol-cytochrome c reductase complex assembly
            factor 4 (UQCC4), mRNA.
ACCESSION   NM_001272051
VERSION     NM_001272051.2
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 917)
  AUTHORS   Liang,C., Zhang,S., Robinson,D., Ploeg,M.V., Wilson,R., Nah,J.,
            Taylor,D., Beh,S., Lim,R., Sun,L., Muoio,D.M., Stroud,D.A. and
            Ho,L.
  TITLE     Mitochondrial microproteins link metabolic cues to respiratory
            chain biogenesis
  JOURNAL   Cell Rep 40 (7), 111204 (2022)
   PUBMED   35977508
REFERENCE   2  (bases 1 to 917)
  AUTHORS   Morgenstern,M., Peikert,C.D., Lubbert,P., Suppanz,I., Klemm,C.,
            Alka,O., Steiert,C., Naumenko,N., Schendzielorz,A., Melchionda,L.,
            Muhlhauser,W.W.D., Knapp,B., Busch,J.D., Stiller,S.B.,
            Dannenmaier,S., Lindau,C., Licheva,M., Eickhorst,C., Galbusera,R.,
            Zerbes,R.M., Ryan,M.T., Kraft,C., Kozjak-Pavlovic,V., Drepper,F.,
            Dennerlein,S., Oeljeklaus,S., Pfanner,N., Wiedemann,N. and
            Warscheid,B.
  TITLE     Quantitative high-confidence human mitochondrial proteome and its
            dynamics in cellular context
  JOURNAL   Cell Metab 33 (12), 2464-2483 (2021)
   PUBMED   34800366
REFERENCE   3  (bases 1 to 917)
  AUTHORS   Daniels,R.J., Peden,J.F., Lloyd,C., Horsley,S.W., Clark,K.,
            Tufarelli,C., Kearney,L., Buckle,V.J., Doggett,N.A., Flint,J. and
            Higgs,D.R.
  TITLE     Sequence, structure and pathology of the fully annotated terminal 2
            Mb of the short arm of human chromosome 16
  JOURNAL   Hum Mol Genet 10 (4), 339-352 (2001)
   PUBMED   11157797
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BQ962326.1, BC023590.2 and AW014549.1.
            
            On Nov 22, 2018 this sequence version replaced NM_001272051.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR5189658.14960.1,
                                           SRR5189658.183458.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA1965299, SAMEA1966682
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000442039.3/ ENSP00000413100.2
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-3                 BQ962326.1         54-56
            4-912               BC023590.2         1-909
            913-917             AW014549.1         25-29               c
FEATURES             Location/Qualifiers
     source          1..917
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="16"
                     /map="16p13.3"
     gene            1..917
                     /gene="UQCC4"
                     /gene_synonym="C16orf91; CCSMST1; gs103; URLC5"
                     /note="ubiquinol-cytochrome c reductase complex assembly
                     factor 4"
                     /db_xref="GeneID:283951"
                     /db_xref="HGNC:HGNC:27558"
                     /db_xref="MIM:620578"
     exon            1..56
                     /gene="UQCC4"
                     /gene_synonym="C16orf91; CCSMST1; gs103; URLC5"
                     /inference="alignment:Splign:2.1.0"
     CDS             25..423
                     /gene="UQCC4"
                     /gene_synonym="C16orf91; CCSMST1; gs103; URLC5"
                     /note="cattle cerebrum and skeletal muscle-specific
                     protein 1 family member; up-regulated in lung cancer 5"
                     /codon_start=1
                     /product="ubiquinol-cytochrome c reductase complex
                     assembly factor 4 precursor"
                     /protein_id="NP_001258980.1"
                     /db_xref="CCDS:CCDS61789.1"
                     /db_xref="GeneID:283951"
                     /db_xref="HGNC:HGNC:27558"
                     /db_xref="MIM:620578"
                     /translation="MNRVLCAPAAGAVRALRLIGWASRSLHPLPGSRDRAHPAAEEED
                     DPDRPIEFSSSKANPHRWSVGHTMGKGHQRPWWKVLPLSCFLVALIIWCYLREESEAD
                     QWLRQVWGEVPEPSDRSEEPETPAAYRART"
     exon            57..917
                     /gene="UQCC4"
                     /gene_synonym="C16orf91; CCSMST1; gs103; URLC5"
                     /inference="alignment:Splign:2.1.0"
     regulatory      891..896
                     /regulatory_class="polyA_signal_sequence"
                     /gene="UQCC4"
                     /gene_synonym="C16orf91; CCSMST1; gs103; URLC5"
                     /note="hexamer: AATAAA"
     polyA_site      917
                     /gene="UQCC4"
                     /gene_synonym="C16orf91; CCSMST1; gs103; URLC5"
                     /note="major polyA site"
ORIGIN      
        1 gtcagtcgag gagtcaaggc agcaatgaat cgtgtcttgt gtgccccggc ggccggggcc
       61 gtccgggcgc tgaggctcat aggctgggct tcccgaagcc ttcatccgtt gcccggttcc
      121 cgggatcggg cccaccctgc cgccgaggaa gaggacgacc ctgaccgccc cattgagttt
      181 tcctccagca aagccaaccc tcaccgctgg tcggtgggcc ataccatggg aaagggacat
      241 cagcggccct ggtggaaggt gctgcccctc agctgcttcc tcgtggcgct gatcatctgg
      301 tgctacctga gggaggagag cgaggcggac cagtggttga gacaggtgtg gggagaggtg
      361 ccagagccca gtgatcgttc tgaggagcct gagactccag ctgcctacag agcgagaact
      421 tgacggggtg cccgctgggg ctggcaggaa gggagccgac agccgccctt cggatttgat
      481 gtcacgtttg cccgtgactg tcctggctat gcgtgcgtcc tcagcactga aggacttggc
      541 tggtggatgg ggcacttggc tatgctgatt cgcgtgaagg cggagcagaa tctcagcaga
      601 tcggaaactg ctcctcgcct ggctcttgat gtccaaggat tccatcggca agacttctca
      661 gatccttggg gaaggtttca gttgcactgt atgctgttgg atttgccaag tctttgtata
      721 acataatcat gtttccaaag cacttctggt gacacttgtc atccagtgtt agtttgcagg
      781 taatttgctt tctgagatag aatatctggc agaagtgtga aactgtattg catgctgcgg
      841 cctgtgcaag gaacacttcc acatgtgagt tttacacaac aacaaatgaa aataaatttt
      901 aattttataa tatggga
//
