LOCUS       NM_001371986           13917 bp    mRNA    linear   PRI 12-OCT-2024
DEFINITION  Homo sapiens unc-80 homolog, NALCN channel complex subunit (UNC80),
            transcript variant 3, mRNA.
ACCESSION   NM_001371986 XM_017003885
VERSION     NM_001371986.1
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 13917)
  AUTHORS   Wie,J., Bharthur,A., Wolfgang,M., Narayanan,V., Ramsey,K.,
            Aranda,K., Zhang,Q., Zhou,Y. and Ren,D.
  CONSRTM   C4RCD Research Group
  TITLE     Intellectual disability-associated UNC80 mutations reveal
            inter-subunit interaction and dendritic function of the NALCN
            channel complex
  JOURNAL   Nat Commun 11 (1), 3351 (2020)
   PUBMED   32620897
  REMARK    GeneRIF: Intellectual disability-associated UNC80 mutations reveal
            inter-subunit interaction and dendritic function of the NALCN
            channel complex.
            Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13917)
  AUTHORS   Chua,H.C., Wulf,M., Weidling,C., Rasmussen,L.P. and Pless,S.A.
  TITLE     The NALCN channel complex is voltage sensitive and directly
            modulated by extracellular calcium
  JOURNAL   Sci Adv 6 (17), eaaz3154 (2020)
   PUBMED   32494638
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 13917)
  AUTHORS   Bramswig,N.C., Bertoli-Avella,A.M., Albrecht,B., Al Aqeel,A.I.,
            Alhashem,A., Al-Sannaa,N., Bah,M., Brohl,K., Depienne,C.,
            Dorison,N., Doummar,D., Ehmke,N., Elbendary,H.M., Gorokhova,S.,
            Heron,D., Horn,D., James,K., Keren,B., Kuechler,A., Ismail,S.,
            Issa,M.Y., Marey,I., Mayer,M., McEvoy-Venneri,J., Megarbane,A.,
            Mignot,C., Mohamed,S., Nava,C., Philip,N., Ravix,C., Rolfs,A.,
            Sadek,A.A., Segebrecht,L., Stanley,V., Trautman,C., Valence,S.,
            Villard,L., Wieland,T., Engels,H., Strom,T.M., Zaki,M.S.,
            Gleeson,J.G., Ludecke,H.J., Bauer,P. and Wieczorek,D.
  TITLE     Genetic variants in components of the NALCN-UNC80-UNC79 ion channel
            complex cause a broad clinical phenotype (NALCN channelopathies)
  JOURNAL   Hum Genet 137 (9), 753-768 (2018)
   PUBMED   30167850
  REMARK    GeneRIF: UNC80 variant is associated with neurodevelopmental
            diseases.
REFERENCE   4  (bases 1 to 13917)
  AUTHORS   He,Y., Ji,X., Yan,H., Ye,X., Liu,Y., Wei,W., Xiao,B. and Sun,Y.
  TITLE     Biallelic UNC80 mutations caused infantile hypotonia with
            psychomotor retardation and characteristic facies 2 in two Chinese
            patients with variable phenotypes
  JOURNAL   Gene 660, 13-17 (2018)
   PUBMED   29572195
  REMARK    GeneRIF: Biallelic UNC80 mutations caused infantile hypotonia with
            psychomotor retardation and characteristic facies 2 in two Chinese
            patients with variable phenotypes
REFERENCE   5  (bases 1 to 13917)
  AUTHORS   Valkanas,E., Schaffer,K., Dunham,C., Maduro,V., du Souich,C.,
            Rupps,R., Adams,D.R., Baradaran-Heravi,A., Flynn,E., Malicdan,M.C.,
            Gahl,W.A., Toro,C. and Boerkoel,C.F.
  TITLE     Phenotypic evolution of UNC80 loss of function
  JOURNAL   Am J Med Genet A 170 (12), 3106-3114 (2016)
   PUBMED   27513830
  REMARK    GeneRIF: Further supporting the UNC80 mutations as causative of
            these siblings' disorder, biallelic mutations in UNC80 have
            recently been described among individuals with an overlapping
            phenotype. This report expands the disease spectrum associated with
            UNC80 mutations
REFERENCE   6  (bases 1 to 13917)
  AUTHORS   Wang,H. and Ren,D.
  TITLE     UNC80 functions as a scaffold for Src kinases in NALCN channel
            function
  JOURNAL   Channels (Austin) 3 (3), 161-163 (2009)
   PUBMED   19535918
  REMARK    GeneRIF: UNC80 functions as a scaffold for Src kinases in NALCN
            channel function.
REFERENCE   7  (bases 1 to 13917)
  AUTHORS   Lu,B., Su,Y., Das,S., Wang,H., Wang,Y., Liu,J. and Ren,D.
  TITLE     Peptide neurotransmitters activate a cation channel complex of
            NALCN and UNC-80
  JOURNAL   Nature 457 (7230), 741-744 (2009)
   PUBMED   19092807
REFERENCE   8  (bases 1 to 13917)
  AUTHORS   Yeh,E., Ng,S., Zhang,M., Bouhours,M., Wang,Y., Wang,M., Hung,W.,
            Aoyagi,K., Melnik-Martinez,K., Li,M., Liu,F., Schafer,W.R. and
            Zhen,M.
  TITLE     A putative cation channel, NCA-1, and a novel protein, UNC-80,
            transmit neuronal activity in C. elegans
  JOURNAL   PLoS Biol 6 (3), e55 (2008)
   PUBMED   18336069
REFERENCE   9  (bases 1 to 13917)
  AUTHORS   Jospin,M., Watanabe,S., Joshi,D., Young,S., Hamming,K., Thacker,C.,
            Snutch,T.P., Jorgensen,E.M. and Schuske,K.
  TITLE     UNC-80 and the NCA ion channels contribute to endocytosis defects
            in synaptojanin mutants
  JOURNAL   Curr Biol 17 (18), 1595-1600 (2007)
   PUBMED   17825559
REFERENCE   10 (bases 1 to 13917)
  AUTHORS   Bramswig,N.C. and Zaki,M.S.
  TITLE     UNC80 Deficiency
  JOURNAL   (in) Adam MP, Feldman J, Mirzaa GM, Pagon RA, Wallace SE and
            Amemiya A (Eds.);
            GENEREVIEWS(R);
            (1993)
   PUBMED   28933810
COMMENT     REVIEWED REFSEQ: This record has been curated by NCBI staff. The
            reference sequence was derived from AC006385.3, AC006464.3 and
            AC007038.6.
            This sequence is a reference standard in the RefSeqGene project.
            
            On Jul 30, 2019 this sequence version replaced XM_017003885.1.
            
            Summary: The protein encoded by this gene is a component of a
            voltage-independent 'leak' ion-channel complex, in which it
            performs essential functions, such as serving as a bridge between
            two other components (sodium leak channel non-selective and UNC79)
            and as a scaffold for Src kinases. Leak channels play an importnat
            role in establishment and maintenance of resting membrane
            potentials in neurons. Mutations in this gene are associated with
            congenital infantile encephalopathy, intellectual disability and
            growth issues. [provided by RefSeq, Aug 2016].
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            RNAseq introns :: single sample supports all introns SAMEA2145743,
                              SAMEA2154665 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            inferred exon combination :: based on alignments, homology
            MANE Ensembl match        :: ENST00000673920.1/ ENSP00000501211.1
            RefSeq Select criteria    :: based on manual assertion,
                                         conservation, longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-333               AC006385.3         88739-89071
            334-382             AC006385.3         90001-90049
            383-539             AC006385.3         92796-92952
            540-841             AC006385.3         94165-94466
            842-965             AC006385.3         102973-103096
            966-1039            AC006385.3         106439-106512
            1040-1179           AC006385.3         110627-110766
            1180-1441           AC006385.3         130487-130748
            1442-1576           AC006385.3         132164-132298
            1577-1793           AC006385.3         133816-134032
            1794-1934           AC006385.3         134719-134859
            1935-2203           AC006385.3         135900-136168
            2204-2572           AC006385.3         137218-137586
            2573-2719           AC006385.3         142814-142960
            2720-2867           AC006385.3         146139-146286
            2868-3016           AC006385.3         148350-148498
            3017-3183           AC006385.3         150909-151075
            3184-3282           AC006385.3         151819-151917
            3283-3491           AC006385.3         156129-156337
            3492-3598           AC006385.3         157449-157555
            3599-3695           AC006385.3         159257-159353
            3696-3868           AC006385.3         166358-166530
            3869-4081           AC006464.3         16357-16569
            4082-4217           AC006464.3         21553-21688
            4218-4351           AC006464.3         24560-24693
            4352-4517           AC006464.3         31694-31859
            4518-4721           AC006464.3         37762-37965
            4722-4822           AC006464.3         39912-40012
            4823-5023           AC006464.3         48364-48564
            5024-5131           AC006464.3         56159-56266
            5132-5270           AC006464.3         57401-57539
            5271-5452           AC006464.3         61376-61557
            5453-5584           AC006464.3         62131-62262
            5585-5771           AC006464.3         65099-65285
            5772-5903           AC006464.3         65851-65982
            5904-6047           AC006464.3         70442-70585
            6048-6148           AC006464.3         73470-73570
            6149-6235           AC006464.3         74567-74653
            6236-6419           AC006464.3         77421-77604
            6420-6514           AC006464.3         79313-79407
            6515-6604           AC006464.3         80443-80532
            6605-6706           AC006464.3         81128-81229
            6707-6887           AC006464.3         83071-83251
            6888-7156           AC006464.3         84820-85088
            7157-7291           AC006464.3         86979-87113
            7292-7430           AC006464.3         88650-88788
            7431-7527           AC006464.3         89446-89542
            7528-7698           AC006464.3         97699-97869
            7699-7791           AC007038.6         1535-1627
            7792-7827           AC007038.6         3010-3045
            7828-8046           AC007038.6         3380-3598
            8047-8247           AC007038.6         11328-11528
            8248-8371           AC007038.6         13659-13782
            8372-8497           AC007038.6         14723-14848
            8498-8621           AC007038.6         16092-16215
            8622-8828           AC007038.6         16955-17161
            8829-9013           AC007038.6         20010-20194
            9014-9179           AC007038.6         20804-20969
            9180-9359           AC007038.6         22420-22599
            9360-9498           AC007038.6         26070-26208
            9499-9555           AC007038.6         28747-28803
            9556-9637           AC007038.6         36057-36138
            9638-9749           AC007038.6         37206-37317
            9750-9949           AC007038.6         37956-38155
            9950-13917          AC007038.6         39220-43187
FEATURES             Location/Qualifiers
     source          1..13917
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="2"
                     /map="2q34"
     gene            1..13917
                     /gene="UNC80"
                     /gene_synonym="C2orf21; UNC-80"
                     /note="unc-80 homolog, NALCN channel complex subunit"
                     /db_xref="GeneID:285175"
                     /db_xref="HGNC:HGNC:26582"
                     /db_xref="MIM:612636"
     exon            1..333
                     /gene="UNC80"
                     /gene_synonym="C2orf21; UNC-80"
                     /inference="alignment:Splign:2.1.0"
     CDS             242..10216
                     /gene="UNC80"
                     /gene_synonym="C2orf21; UNC-80"
                     /note="isoform 3 is encoded by transcript variant 3;
                     protein unc-80 homolog; unc-80 homolog, NALCN activator"
                     /codon_start=1
                     /product="protein unc-80 homolog isoform 3"
                     /protein_id="NP_001358915.1"
                     /db_xref="CCDS:CCDS92937.1"
                     /db_xref="GeneID:285175"
                     /db_xref="HGNC:HGNC:26582"
                     /db_xref="MIM:612636"
                     /translation="MVKRKSSEGQEQDGGRGIPLPIQTFLWRQTSAFLRPKLGKQYEA
                     SCVSFERVLVENKLHGLSPALSEAIQSISRWELVQAALPHVLHCTATLLSNRNKLGHQ
                     DKLGVAETKLLHTLHWMLLEAPQDCNNERFGGTDRGSSWGGSSSAFIHQVENQGSPGQ
                     PCQSSSNDEEENNRRKIFQNSMATVELFVFLFAPLVHRIKESDLTFRLASGLVIWQPM
                     WEHRQPGVSGFTALVKPIRNIITAKRSSPINSQSRTCESPNQDARHLEGLQVVCETFQ
                     SDSISPKATISGCHRGNSFDGSLSSQTSQERGPSHSRASLVIPPCQRSRYATYFDVAV
                     LRCLLQPHWSEEGTQWSLMYYLQRLRHMLEEKPEKPPEPDIPLLPRPRSSSMVAAAPS
                     LVNTHKTQDLTMKCNEEEKSLSSEAFSKVSLTNLRRSAVPDLSSDLGMNIFKKFKSRK
                     EDRERKGSIPFHHTGKRRPRRMGVPFLLHEDHLDVSPTRSTFSFGSFSGLGEDRRGIE
                     KGGWQTTILGKLTRRGSSDAATEMESLSARHSHSHHTLVSDLPDPSNSHGENTVKEVR
                     SQISTITVATFNTTLASFNVGYADFFNEHMRKLCNQVPIPEMPHEPLACANLPRSLTD
                     SCINYSYLEDTEHIDGTNNFVHKNGMLDLSVVLKAVYLVLNHDISSRICDVALNIVEC
                     LLQLGVVPCVEKNRKKSENKENETLEKRPSEGAFQFKGVSGSSTCGFGGPAVSGAGDG
                     GGEEGGGGDGGGGGGDGGGGGGGGGGPYEKNDKNQEKDESTPVSNHRLALTMLIKIVK
                     SLGCAYGCGEGHRGLSGDRLRHQVFRENAQNCLTKLYKLDKMQFRQTMRDYVNKDSLN
                     NVVDFLHALLGFCMEPVTDNKAGFGNNFTTVDNKSTAQNVEGIIVSAMFKSLITRCAS
                     TTHELHSPENLGLYCDIRQLVQFIKEAHGNVFRRVALSALLDSAEKLAPGKKVEENEQ
                     ESKPAGSKRSEAGSIVDKGQVSSAPEECRSFMSGRPSQTPEHDEQMQGANLGRKDFWR
                     KMFKSQSAASDTSSQSEQDTSECTTAHSGTTSDRRARSRSRRISLRKKLKLPIGNWLK
                     RSSLSGLADGVEDLLDISSVDRLSFIRQSSKVKFTSAVKLSEGGPGSGMENGRDEEEN
                     FFKRLGCHSFDDHLSPNQDGGKSKNVVNLGAIRQGMKRFQFLLNCCEPGTIPDASILA
                     AALDLEAPVVARAALFLECARFVHRCNRGNWPEWMKGHHVNITKKGLSRGRSPIVGNK
                     RNQKLQWNAAKLFYQWGDAIGVRLNELCHGESESPANLLGLIYDEETKRRLRKEDEEE
                     DFLDDSTVNPSKCGCPFALKMAACQLLLEITTFLRETFSCLPRPRTEPLVDLESCRLR
                     LDPELDRHRYERKISFAGVLDENEDSKDSLHSSSHTLKSDAGVEEKKVPSRKIRIGGS
                     RLLQIKGTRSFQVKKGGSLSSIRRVGSLKSSKLSRQDSESEAEELQLSQSRDTVTDLE
                     GSPWSASEPSIEPEGMSNAGAEENYHRNMSWLHVMILLCNQQSFICTHVDYCHPHCYL
                     HHSRSCARLVRAIKLLYGDSVDSLRESSNISSVALRGKKQKECSDKSCLRTPSLKKRV
                     SDANLEGKKDSGMLKYIRLQVMSLSPAPLSLLIKAAPILTEEMYGDIQPAAWELLLSM
                     DEHMAGAAAAMFLLCAVKVPEAVSDMLMSEFHHPETVQRLNAVLKFHTLWRFRYQVWP
                     RMEEGAQQIFKIPPPSINFTLPSPVLGMPSVPMFDPPWVPQCSGSVQDPINEDQSKSF
                     SARAVSRSHQRAEHILKNLQQEEEKKRLGREASLITAIPITQEACYEPTCTPNSEPEE
                     EVEEVTNLASRRLSVSPSCTSSTSHRNYSFRRGSVWSVRSAVSAEDEEHTTEHTPNHH
                     VPQPPQAVFPACICAAVLPIVHLMEDGEVREDGVAVSAVAQQVLWNCLIEDPSTVLRH
                     FLEKLTISNRQDELMYMLRKLLLNIGDFPAQTSHILFNYLVGLIMYFVRTPCEWGMDA
                     ISATLTFLWEVVGYVEGLFFKDLKQTMKKEQCEVKLLVTASMPGTKTLVVHGQNECDI
                     PTQLPVHEDTQFEALLKECLEFFNIPESQSTHYFLMDKRWNLIHYNKTYVRDIYPFRR
                     SVSPQLNLVHMHPEKGQELIQKQVFTRKLEEVGRVLFLISLTQKIPTAHKQSHVSMLQ
                     EDLLRLPSFPRSAIDAEFSLFSDPQAGKELFGLDTLQKSLWIQLLEEMFLGMPSEFPW
                     GDEIMLFLNVFNGALILHPEDSALLRQYAATVINTAVHFNHLFSLSGYQWILPTMLQV
                     YSDYESNPQLRQAIEFACHQFYILHRKPFVLQLFASVAPLLEFPDAANNGPSKGVSAQ
                     CLFDLLQSLEGETTDILDILELVKAEKPLKSLDFCYGNEDLTFSISEAIKLCVTVVAY
                     APESFRSLQMLMVLEALVPCYLQKLKRQTSQVETVPAAREEIAATAALATSLQALLYS
                     VEVLTRPMTAPQMSRCDQGHKGTTTANHTMSSGVNTRYQEQGAKLHFIRENLHLLEEG
                     QGIPREELDERIAREEFRRPRESLLNICTEFYKHCGPRLKILQNLAGEPRVIALELLD
                     VKSHMRLAEIAHSLLKLAPYDTQTMESRGLRRYIMEMLPITDWTAEAVRPALILILKR
                     LDRMFNKIHKMPTLRRQVEWEPASNLIEGVCLTLQRQPIISFLPHLRSLINVCVNLVM
                     GVVGPSSVADGLPLLHLSPYLSPPLPFSTAVVRLVALQIQALKEDFPLSHVISPFTNQ
                     ERREGMLLNLLIPFVLTVGSGSKDSPWLEQPEVQLLLQTVINVLLPPRIISTSRSKNF
                     MLESSPAHCSTPGDAGKDLRREGLAESTSQAAYLALKVILVCFERQLGSQWYWLSLQV
                     KEMALRKVGGLALWDFLDFIVRTRIPIFVLLRPFIQCKLLAQPAENHEELSARQHIAD
                     QLERRFIPRPLCKSSLIAEFNSELKILKEAVHSGSAYQGKTSISTVGTSTSAYRLSLA
                     TMSRSNTGTGTVWEQDSEPSQQASQDTLSRTDEEDEENDSISMPSVVSEQEAYLLSAI
                     GRRRFSSHVSSMSVPQAEVGMLPSQSEPNVLDDSQGLAAEGSLSRVASIQSEPGQQNL
                     LVQQPLGRKRGLRQLRRPLLSRQKTQTEPRNRQGARLSTTRRSIQPKTKPSADQKRSV
                     TFIEAQPEPAAAPTDALPATGQLQGCSPAPSRKPEAMDEPVLTSSPAIVVADLHSVSP
                     KQSENFPTEEGEKEEDTEAQGATAHSPLSAQLSDPDDFTGLETSSLLQHGDTVLHISE
                     ENGMENPLLSSQFTFTPTELGKTDAVLDESHV"
     exon            334..382
                     /gene="UNC80"
                     /gene_synonym="C2orf21; UNC-80"
                     /inference="alignment:Splign:2.1.0"
     exon            383..539
                     /gene="UNC80"
                     /gene_synonym="C2orf21; UNC-80"
                     /inference="alignment:Splign:2.1.0"
     exon            540..841
                     /gene="UNC80"
                     /gene_synonym="C2orf21; UNC-80"
                     /inference="alignment:Splign:2.1.0"
     exon            842..965
                     /gene="UNC80"
                     /gene_synonym="C2orf21; UNC-80"
                     /inference="alignment:Splign:2.1.0"
     exon            966..1039
                     /gene="UNC80"
                     /gene_synonym="C2orf21; UNC-80"
                     /inference="alignment:Splign:2.1.0"
     exon            1040..1179
                     /gene="UNC80"
                     /gene_synonym="C2orf21; UNC-80"
                     /inference="alignment:Splign:2.1.0"
     exon            1180..1441
                     /gene="UNC80"
                     /gene_synonym="C2orf21; UNC-80"
                     /inference="alignment:Splign:2.1.0"
     exon            1442..1576
                     /gene="UNC80"
                     /gene_synonym="C2orf21; UNC-80"
                     /inference="alignment:Splign:2.1.0"
     exon            1577..1793
                     /gene="UNC80"
                     /gene_synonym="C2orf21; UNC-80"
                     /inference="alignment:Splign:2.1.0"
     exon            1794..1934
                     /gene="UNC80"
                     /gene_synonym="C2orf21; UNC-80"
                     /inference="alignment:Splign:2.1.0"
     exon            1935..2203
                     /gene="UNC80"
                     /gene_synonym="C2orf21; UNC-80"
                     /inference="alignment:Splign:2.1.0"
     exon            2204..2572
                     /gene="UNC80"
                     /gene_synonym="C2orf21; UNC-80"
                     /inference="alignment:Splign:2.1.0"
     exon            2573..2719
                     /gene="UNC80"
                     /gene_synonym="C2orf21; UNC-80"
                     /inference="alignment:Splign:2.1.0"
     exon            2720..2867
                     /gene="UNC80"
                     /gene_synonym="C2orf21; UNC-80"
                     /inference="alignment:Splign:2.1.0"
     exon            2868..3016
                     /gene="UNC80"
                     /gene_synonym="C2orf21; UNC-80"
                     /inference="alignment:Splign:2.1.0"
     exon            3017..3183
                     /gene="UNC80"
                     /gene_synonym="C2orf21; UNC-80"
                     /inference="alignment:Splign:2.1.0"
     exon            3184..3282
                     /gene="UNC80"
                     /gene_synonym="C2orf21; UNC-80"
                     /inference="alignment:Splign:2.1.0"
     exon            3283..3491
                     /gene="UNC80"
                     /gene_synonym="C2orf21; UNC-80"
                     /inference="alignment:Splign:2.1.0"
     exon            3492..3598
                     /gene="UNC80"
                     /gene_synonym="C2orf21; UNC-80"
                     /inference="alignment:Splign:2.1.0"
     exon            3599..3695
                     /gene="UNC80"
                     /gene_synonym="C2orf21; UNC-80"
                     /inference="alignment:Splign:2.1.0"
     exon            3696..3868
                     /gene="UNC80"
                     /gene_synonym="C2orf21; UNC-80"
                     /inference="alignment:Splign:2.1.0"
     exon            3869..4081
                     /gene="UNC80"
                     /gene_synonym="C2orf21; UNC-80"
                     /inference="alignment:Splign:2.1.0"
     exon            4082..4217
                     /gene="UNC80"
                     /gene_synonym="C2orf21; UNC-80"
                     /inference="alignment:Splign:2.1.0"
     exon            4218..4351
                     /gene="UNC80"
                     /gene_synonym="C2orf21; UNC-80"
                     /inference="alignment:Splign:2.1.0"
     exon            4352..4517
                     /gene="UNC80"
                     /gene_synonym="C2orf21; UNC-80"
                     /inference="alignment:Splign:2.1.0"
     exon            4518..4721
                     /gene="UNC80"
                     /gene_synonym="C2orf21; UNC-80"
                     /inference="alignment:Splign:2.1.0"
     exon            4722..4822
                     /gene="UNC80"
                     /gene_synonym="C2orf21; UNC-80"
                     /inference="alignment:Splign:2.1.0"
     exon            4823..5023
                     /gene="UNC80"
                     /gene_synonym="C2orf21; UNC-80"
                     /inference="alignment:Splign:2.1.0"
     exon            5024..5131
                     /gene="UNC80"
                     /gene_synonym="C2orf21; UNC-80"
                     /inference="alignment:Splign:2.1.0"
     exon            5132..5270
                     /gene="UNC80"
                     /gene_synonym="C2orf21; UNC-80"
                     /inference="alignment:Splign:2.1.0"
     exon            5271..5452
                     /gene="UNC80"
                     /gene_synonym="C2orf21; UNC-80"
                     /inference="alignment:Splign:2.1.0"
     exon            5453..5584
                     /gene="UNC80"
                     /gene_synonym="C2orf21; UNC-80"
                     /inference="alignment:Splign:2.1.0"
     exon            5585..5771
                     /gene="UNC80"
                     /gene_synonym="C2orf21; UNC-80"
                     /inference="alignment:Splign:2.1.0"
     exon            5772..5903
                     /gene="UNC80"
                     /gene_synonym="C2orf21; UNC-80"
                     /inference="alignment:Splign:2.1.0"
     exon            5904..6047
                     /gene="UNC80"
                     /gene_synonym="C2orf21; UNC-80"
                     /inference="alignment:Splign:2.1.0"
     exon            6048..6148
                     /gene="UNC80"
                     /gene_synonym="C2orf21; UNC-80"
                     /inference="alignment:Splign:2.1.0"
     exon            6149..6235
                     /gene="UNC80"
                     /gene_synonym="C2orf21; UNC-80"
                     /inference="alignment:Splign:2.1.0"
     exon            6236..6419
                     /gene="UNC80"
                     /gene_synonym="C2orf21; UNC-80"
                     /inference="alignment:Splign:2.1.0"
     exon            6420..6514
                     /gene="UNC80"
                     /gene_synonym="C2orf21; UNC-80"
                     /inference="alignment:Splign:2.1.0"
     exon            6515..6604
                     /gene="UNC80"
                     /gene_synonym="C2orf21; UNC-80"
                     /inference="alignment:Splign:2.1.0"
     exon            6605..6706
                     /gene="UNC80"
                     /gene_synonym="C2orf21; UNC-80"
                     /inference="alignment:Splign:2.1.0"
     exon            6707..6887
                     /gene="UNC80"
                     /gene_synonym="C2orf21; UNC-80"
                     /inference="alignment:Splign:2.1.0"
     exon            6888..7156
                     /gene="UNC80"
                     /gene_synonym="C2orf21; UNC-80"
                     /inference="alignment:Splign:2.1.0"
     exon            7157..7291
                     /gene="UNC80"
                     /gene_synonym="C2orf21; UNC-80"
                     /inference="alignment:Splign:2.1.0"
     exon            7292..7430
                     /gene="UNC80"
                     /gene_synonym="C2orf21; UNC-80"
                     /inference="alignment:Splign:2.1.0"
     exon            7431..7527
                     /gene="UNC80"
                     /gene_synonym="C2orf21; UNC-80"
                     /inference="alignment:Splign:2.1.0"
     exon            7528..7698
                     /gene="UNC80"
                     /gene_synonym="C2orf21; UNC-80"
                     /inference="alignment:Splign:2.1.0"
     exon            7699..7791
                     /gene="UNC80"
                     /gene_synonym="C2orf21; UNC-80"
                     /inference="alignment:Splign:2.1.0"
     exon            7792..7827
                     /gene="UNC80"
                     /gene_synonym="C2orf21; UNC-80"
                     /inference="alignment:Splign:2.1.0"
     exon            7828..8046
                     /gene="UNC80"
                     /gene_synonym="C2orf21; UNC-80"
                     /inference="alignment:Splign:2.1.0"
     exon            8047..8247
                     /gene="UNC80"
                     /gene_synonym="C2orf21; UNC-80"
                     /inference="alignment:Splign:2.1.0"
     exon            8248..8371
                     /gene="UNC80"
                     /gene_synonym="C2orf21; UNC-80"
                     /inference="alignment:Splign:2.1.0"
     exon            8372..8497
                     /gene="UNC80"
                     /gene_synonym="C2orf21; UNC-80"
                     /inference="alignment:Splign:2.1.0"
     exon            8498..8621
                     /gene="UNC80"
                     /gene_synonym="C2orf21; UNC-80"
                     /inference="alignment:Splign:2.1.0"
     exon            8622..8828
                     /gene="UNC80"
                     /gene_synonym="C2orf21; UNC-80"
                     /inference="alignment:Splign:2.1.0"
     exon            8829..9013
                     /gene="UNC80"
                     /gene_synonym="C2orf21; UNC-80"
                     /inference="alignment:Splign:2.1.0"
     exon            9014..9179
                     /gene="UNC80"
                     /gene_synonym="C2orf21; UNC-80"
                     /inference="alignment:Splign:2.1.0"
     exon            9180..9359
                     /gene="UNC80"
                     /gene_synonym="C2orf21; UNC-80"
                     /inference="alignment:Splign:2.1.0"
     exon            9360..9498
                     /gene="UNC80"
                     /gene_synonym="C2orf21; UNC-80"
                     /inference="alignment:Splign:2.1.0"
     exon            9499..9555
                     /gene="UNC80"
                     /gene_synonym="C2orf21; UNC-80"
                     /inference="alignment:Splign:2.1.0"
     exon            9556..9637
                     /gene="UNC80"
                     /gene_synonym="C2orf21; UNC-80"
                     /inference="alignment:Splign:2.1.0"
     exon            9638..9749
                     /gene="UNC80"
                     /gene_synonym="C2orf21; UNC-80"
                     /inference="alignment:Splign:2.1.0"
     exon            9750..9949
                     /gene="UNC80"
                     /gene_synonym="C2orf21; UNC-80"
                     /inference="alignment:Splign:2.1.0"
     exon            9950..13917
                     /gene="UNC80"
                     /gene_synonym="C2orf21; UNC-80"
                     /inference="alignment:Splign:2.1.0"
     regulatory      13897..13902
                     /regulatory_class="polyA_signal_sequence"
                     /gene="UNC80"
                     /gene_synonym="C2orf21; UNC-80"
                     /note="hexamer: AATAAA"
     polyA_site      13917
                     /gene="UNC80"
                     /gene_synonym="C2orf21; UNC-80"
                     /note="major polyA site"
ORIGIN      
        1 gctccgagcg cccccctcct cgctccgcgg ctcctccagc cctcccctcc tcccgcagcc
       61 atgttccacg cgcggggagg ggtgggggga ggggagaggc acgggggatc agggcggaga
      121 gagccggctc tgcctcgggg aaggagggga tgagagttgg gagcagcggg aggaggcggc
      181 ggcggcggct agcgaggaga cagagctggg tcctgcagta ggactcccgg gagccaccat
      241 tatggtgaag aggaagagct ccgagggcca ggagcaggac ggcggccgcg gcatccccct
      301 gcccatccag accttcctgt ggcggcaaac cagtgcattt ttgaggccca aactggggaa
      361 gcaatatgaa gcttcttgtg tgtcctttga gcgagtgttg gtagaaaaca agctgcatgg
      421 cctctctcca gctctctctg aagccatcca gagcatttcc agatgggaac tggtgcaagc
      481 tgctttgcct catgtcctcc actgcactgc aaccctgctt tcaaaccgaa acaagctagg
      541 ccaccaggat aaattgggtg ttgctgagac aaagctcctt cacactctac actggatgct
      601 tctggaggcc ccccaggact gcaacaatga gcggtttggg ggtacagacc gaggctccag
      661 ctggggtgga agcagcagtg ctttcatcca ccaggttgaa aaccagggtt ctccagggca
      721 gccttgccaa agcagctcta atgacgaaga agagaacaac cgaagaaaga tcttccagaa
      781 ctccatggct actgtggagc tcttcgtgtt tctgtttgct cccctggtac acaggatcaa
      841 ggaatctgac ctcaccttcc gtctggccag tgggcttgtt atatggcagc ccatgtggga
      901 acacagacag cccggagtct ctggctttac cgcactggtg aagcccatca ggaacatcat
      961 tacagctaag agaagttctc ctatcaacag tcaaagccgg acctgtgaat caccaaatca
     1021 agatgcaaga cacttagagg gactccaggt ggtttgtgaa acattccagt ctgattccat
     1081 ctcacccaag gccaccattt caggctgtca ccgaggaaac tcctttgatg gaagtctgtc
     1141 ctcccaaact tcccaggaaa gaggcccatc acattccagg gcctctcttg tgatacctcc
     1201 gtgccaaagg tcccgctatg ccacctactt tgacgttgct gttctgcgct gcctacttca
     1261 gccccattgg tctgaggaag gcactcagtg gtctctgatg tactatctac aaaggctgcg
     1321 acacatgttg gaagagaagc cagaaaagcc tccggagcca gatattcctc tcctgcccag
     1381 acccaggagt agctccatgg tggcagcagc tccctcacta gtgaacaccc acaaaaccca
     1441 agatctcacc atgaagtgta acgaggagga aaaatctctt agctctgagg ccttttccaa
     1501 ggtttcactg accaatctgc gtagatctgc agtcccagat ctttcttcag acctgggcat
     1561 gaatattttt aaaaagttca agagccgcaa agaagaccga gagaggaaag gctccattcc
     1621 attccaccac acaggcaaga ggaggccacg gagaatggga gtgcccttcc tgcttcacga
     1681 ggaccacctg gatgtgtccc ccacgcgcag cacattctcc tttggaagtt tctctgggct
     1741 gggagaagac aggcgaggaa ttgagaaagg aggctggcaa accaccattt tagggaaatt
     1801 gacccggcga ggcagttcag atgcagccac tgagatggag agtctgagcg ccaggcattc
     1861 ccactcccat cacaccctgg taagcgacct gccggacccc tccaacagcc atggagaaaa
     1921 caccgtcaag gaagtgcgat ctcagatctc caccatcaca gttgcgacct tcaataccac
     1981 tttggcgtca ttcaacgtag gctatgcaga ctttttcaat gagcatatga ggaaactctg
     2041 caaccaggtg cctatcccgg agatgccaca tgaacctctg gcatgtgcta acctacctcg
     2101 aagcctcaca gactcctgca taaactacag ctacctagag gacacagaac atattgacgg
     2161 gaccaataac tttgtccaca agaatggaat gcttgatctt tctgtagttc tgaaggctgt
     2221 ttatcttgtc cttaatcatg acatcagctc tcgtatctgt gacgtggcgc taaacattgt
     2281 ggaatgcttg cttcaacttg gtgtggtgcc ctgtgtagaa aagaatagaa agaagagtga
     2341 aaacaaggaa aatgagacct tggaaaagag gccaagtgag ggagctttcc aattcaaagg
     2401 agtatctgga agttccacct gtggattcgg aggccctgct gttagtggag ctggagatgg
     2461 tggaggagaa gaaggaggag gtggagatgg aggaggtgga ggaggtgatg gaggaggagg
     2521 tggaggaggt ggaggcggcc cttatgagaa gaatgataag aaccaagaga aggatgaaag
     2581 tacacctgta agcaaccata ggcttgctct aacaatgctc atcaaaatag tgaagtcttt
     2641 gggatgtgcc tatggttgtg gtgaaggaca ccgagggctc tctggagatc gtctgagaca
     2701 ccaggtattc cgagagaatg cccagaactg cctcactaag ctatacaagc tagataagat
     2761 gcagttccga caaaccatga gggactatgt gaacaaggac tctctcaata atgtagtgga
     2821 cttcttgcat gctttgctag gattttgtat ggagccggtc actgacaaca aggctgggtt
     2881 tggaaataac ttcaccacag tggacaacaa atccacagcc caaaatgtgg aaggcattat
     2941 cgtcagcgcc atgtttaaat ccctcatcac acgctgcgct tcaaccacac atgaattgca
     3001 cagccctgag aatctgggac tgtattgtga cattcgtcag ctggtccagt ttatcaaaga
     3061 ggctcatggg aatgtcttca ggagagtggc cctcagcgct ctgcttgaca gtgccgagaa
     3121 gttagcacca gggaaaaagg tggaggagaa tgaacaggaa tctaagcctg caggcagtaa
     3181 aaggtcagag gcgggaagca ttgtggataa aggccaggta tcctctgcac ctgaggaatg
     3241 tcgcagcttc atgtctggtc gcccctcaca gactccagag cacgatgaac aaatgcaagg
     3301 agccaacttg gggcggaaag atttctggcg taagatgttc aagtcccaga gtgcagcaag
     3361 tgacaccagc agccagtctg aacaggacac ttcagaatgc acgactgccc actcagggac
     3421 cacctctgac cgacgtgccc gctcacgatc ccgcagaatt tccctccgaa agaagcttaa
     3481 actccccata gggaactggc tgaagagatc atccctctca ggcctggcag atggtgtgga
     3541 ggacctcctg gacattagct ctgtggaccg actctctttc atcaggcaaa gctccaaggt
     3601 caaattcact agtgctgtga agctttctga aggtgggcca ggaagtggca tggaaaatgg
     3661 aagagatgaa gaggagaatt tcttcaagcg tcttggttgc cacagttttg atgatcatct
     3721 ctctcccaac caagatggtg gaaaaagcaa aaacgtggtg aatcttggag caatccgaca
     3781 aggcatgaaa cgcttccaat ttctgttaaa ctgctgtgag ccagggacaa ttcctgatgc
     3841 ctccatccta gcagctgcct tggatctaga agcccctgtg gtggccagag cagccttgtt
     3901 cctggaatgt gctcgttttg ttcaccgctg caaccgtggc aactggccag agtggatgaa
     3961 agggcaccac gtgaacatca ccaagaaagg actttcccgg ggacgctctc ccattgtggg
     4021 caacaagcga aaccagaagc tgcagtggaa tgcagccaag ctcttctacc aatggggaga
     4081 cgcaattggc gtccgattga atgagctgtg ccacggggaa agtgagagcc cagccaacct
     4141 gctgggtctc atttacgatg aagagaccaa gaggagactt agaaaggagg atgaggagga
     4201 agacttttta gatgacagta ctgtgaaccc ctctaaatgc ggttgcccct ttgccttgaa
     4261 gatggcagca tgtcagcttc ttctggagat taccaccttc ctgcgagaga ccttttcttg
     4321 cctgcccaga cctcgcactg agcctctggt ggacttggag agctgcagac ttcgtttgga
     4381 tcccgagttg gaccggcaca gatatgagag gaagatcagc tttgctgggg tcctggacga
     4441 aaatgaagac tcaaaagatt ctctccacag cagcagccac actctcaaat cagatgcagg
     4501 agtcgaggag aagaaagttc ccagcaggaa gatcaggata ggaggttctc gcctgctcca
     4561 gattaaagga acccgcagtt tccaggtgaa gaaggggggt tccttgtcca gcattcgccg
     4621 ggtcggcagc ttaaagagca gcaagttatc acggcaggac tcagagtctg aggctgagga
     4681 gctgcagctg tcccagagca gggacactgt cactgaccta gaagggagtc cttggagtgc
     4741 aagcgagccc agcattgagc cagagggaat gagtaatgcc ggcgcggagg agaattacca
     4801 cagaaacatg tcgtggcttc atgtgatgat cttgctgtgc aatcagcaga gtttcatctg
     4861 cactcacgtt gactactgcc atccccactg ctacctgcac cacagccgct cctgtgcccg
     4921 actggtcaga gccatcaagc tactctatgg agacagtgtg gactccctga gggaaagcag
     4981 caacatcagc agtgtggctc tccggggcaa gaaacagaaa gaatgctcag ataagtcatg
     5041 cctgaggaca ccttctctaa agaagagagt ttcagatgcc aatctggaag gaaaaaaaga
     5101 ttccggaatg ctgaagtaca tcagacttca ggtgatgagc ttgtcgcctg ctcccttatc
     5161 tctgttaatc aaggcagcac caattctgac agaggagatg tacggagaca tccagccagc
     5221 tgcctgggag ctcctgctca gcatggatga gcacatggca ggggcagcag ctgccatgtt
     5281 cctgctgtgt gcagtgaagg tgcctgaggc cgtgtccgac atgctgatgt cagagttcca
     5341 ccacccggag actgtgcaga ggctgaacgc tgtcctcaag ttccacacgc tctggaggtt
     5401 tcgctatcag gtctggcccc ggatggagga aggggcacag cagattttta agattccgcc
     5461 tcccagtatc aatttcaccc ttccctcgcc ggtgcttgga atgccatccg tcccaatgtt
     5521 tgacccaccg tgggttcctc agtgcagcgg gagtgtccag gaccccatta atgaagacca
     5581 gtctaaatcc ttttcagccc gggctgtgtc ccgctcccat caaagggcag aacacatctt
     5641 aaagaacttg cagcaggagg aagaaaagaa acgacttggt agagaagcca gcctcatcac
     5701 tgccatcccc atcacccagg aggcttgcta tgagcccaca tgcacgccca actcagaacc
     5761 ggaagaagaa gtagaagaag tcaccaatct ggcatcccgt cgactgtctg tgagtccatc
     5821 ctgcacctcc agcacttccc acaggaatta ttccttccgc cgcgggtcag tctggtcagt
     5881 gcgttcagcc gtcagtgctg aagatgagga acataccact gaacacacgc cgaaccacca
     5941 tgtgcctcag cccccacaag cagtgttccc agcatgcatc tgtgcagcag tacttcccat
     6001 tgttcatctg atggaggatg gtgaggtgcg ggaagatgga gtagcagtga gtgctgtggc
     6061 tcaacaagtc ttatggaact gtctaattga agatccatca acggttcttc gacattttct
     6121 ggaaaaactg accatcagca atagacaaga tgagttaatg tacatgctgc gcaaacttct
     6181 cttgaatatt ggagactttc ctgctcagac atctcacatc ctattcaact atttggtagg
     6241 attaatcatg tactttgtgc ggaccccctg cgagtggggg atggatgcca tttcagccac
     6301 cctgacattc ctgtgggagg tggtgggtta cgtggagggc ctcttcttca aggatctcaa
     6361 gcagacgatg aagaaggagc agtgtgaggt gaagctcctg gtgaccgctt caatgccagg
     6421 tactaaaacc ttggtagttc atggacagaa tgagtgcgat atcccaaccc agttaccagt
     6481 ccatgaagac actcaatttg aagccctgtt gaaggagtgt ctggagtttt ttaatatccc
     6541 agaatcccag tcaacacatt attttcttat ggataaacga tggaacctta tccactacaa
     6601 taagacctat gttcgagata tttatccttt ccggaggtca gtatctcccc agctgaatct
     6661 tgtacatatg catccagaga agggacagga gctcattcag aaacaggtgt tcacccgaaa
     6721 gctggaagaa gtagggcggg tgttgtttct catctcccta acccagaaga tccccacagc
     6781 ccacaaacag tcccacgtct ccatgcttca ggaagacctc ctccgcctgc cctcattccc
     6841 tcgtagtgct attgatgctg agttttcact cttcagtgat cctcaagctg gaaaggaact
     6901 gtttggcctc gacactcttc agaaaagctt gtggatccag ctgctggagg aaatgttcct
     6961 gggcatgccg agcgagtttc catggggaga cgaaatcatg cttttcctca acgtttttaa
     7021 cggggctctg atcctccacc cggaagacag tgccctgctc aggcagtatg ctgccaccgt
     7081 catcaacacc gcggtgcact tcaaccacct cttctctctc agcggctacc agtggattct
     7141 ccccaccatg ctgcaggtgt actccgacta tgaaagcaat ccccagctgc gtcaagccat
     7201 cgaatttgcc tgtcaccagt tctatattct acaccggaag ccctttgtgc tccagctgtt
     7261 tgctagtgtg gcccctctcc tggaatttcc tgatgctgcc aataatgggc ccagcaaagg
     7321 tgtgtcagct cagtgcctgt ttgacttgct gcagtcccta gagggagaga ccaccgacat
     7381 attagacatc ttagagctgg tcaaagctga gaagcctctc aagtcattag atttctgcta
     7441 tggaaacgaa gatctgacat tttctatcag tgaagccatt aagctctgtg tcactgtggt
     7501 ggcgtatgct cccgaatcat tcagaagtct tcagatgctg atggtcttag aagccttagt
     7561 tccatgttac ctacaaaagc taaagaggca gacatcacag gtggagacag tacctgctgc
     7621 ccgagaggag attgcggcca ctgctgctct tgcgacgtcc ctacaggccc ttttgtacag
     7681 tgtagaggtc ctcaccaggc ccatgacagc cccacagatg agcaggtgtg accaaggtca
     7741 taagggaacc accacagcca atcacaccat gtcgtctggg gtgaacacca ggtaccagga
     7801 acaaggagcc aaactgcact ttatcaggga aaaccttcat ttactggagg aagggcaagg
     7861 cattcccaga gaggaactgg atgaacgaat tgctcgggaa gagttcagaa gaccccggga
     7921 gtccttactg aatatttgca ctgagttcta taagcactgt gggccacggc tgaagatctt
     7981 gcaaaatctg gctggggagc ctcgggtcat tgccttggaa ctgctggatg tgaagtctca
     8041 catgaggttg gcagaaattg cacactccct tctgaagctg gcaccatatg acactcagac
     8101 aatggagagt cgtgggcttc ggcgctacat catggagatg ctacccatta ctgactggac
     8161 agctgaggca gtgaggccgg ccctcatcct cattttaaaa agattggata gaatgttcaa
     8221 caaaattcat aagatgccta ctttgaggcg acaggttgag tgggagcctg ccagcaattt
     8281 gattgaaggg gtttgtttga cacttcagag gcagccaatc atatccttcc tgcctcacct
     8341 taggtcactg atcaatgtct gtgtcaatct ggtgatggga gtggtaggac cttccagtgt
     8401 tgctgatgga ttaccccttc ttcatctcag cccttatctc tcaccacctc tgcccttcag
     8461 cacagctgtt gtccggcttg tagcattgca gatacaggct ttaaaagaag attttccttt
     8521 aagccatgtg atctccccat tcaccaatca agagcgaagg gaggggatgc ttttaaatct
     8581 gctcatccca tttgtgctca cagtaggatc tggaagcaaa gatagcccat ggctggagca
     8641 gcctgaggtg cagctgctgc tgcagacagt catcaatgta ctcctcccac cgcggatcat
     8701 cagcacatcc aggagcaaga acttcatgtt agagagctcc ccagcccact gctccacccc
     8761 tggggatgcg gggaaagact tgcgcaggga agggctggct gagtccacca gccaagcagc
     8821 atacttggcg ctgaaggtga ttctcgtctg ctttgagagg cagctcggaa gccagtggta
     8881 ctggctgagc ctccaggtga aggagatggc tctgcggaag gtgggaggcc tggccctttg
     8941 ggatttcctc gacttcatcg tgcggacccg aatacccatc tttgtgcttt tgcgcccttt
     9001 catccagtgc aagctgctgg cccaaccagc agagaatcat gaagagcttt ccgcccggca
     9061 acatattgcc gaccagctgg agcggcgctt cataccacgc cctttgtgta agagctcgct
     9121 cattgctgag ttcaacagtg aactaaaaat tctaaaagag gcagttcata gtggatcagc
     9181 ctaccaaggc aagacatcca tcagtaccgt gggcacctcc acctctgctt accgcctgag
     9241 cttggccacc atgtcccgct ctaacacggg cacgggcact gtctgggagc aggacagtga
     9301 gccatcccag caggcttcgc aggacaccct gagtcggact gatgaggaag atgaggaaaa
     9361 tgactctata agcatgccca gcgtggtaag tgaacaagaa gcttacctcc tgagtgccat
     9421 tggaaggagg cgattctcca gccatgtctc cagcatgtct gtacctcagg ctgaggtggg
     9481 catgctaccc agccagagtg aacctaatgt cctcgatgac tcccagggcc tggccgccga
     9541 gggcagcctc tctagggtgg caagtataca gagtgaacct ggtcaacaga acctccttgt
     9601 tcagcagccg ctggggagga agaggggcct gaggcagcta agacgtcctc tactatcacg
     9661 tcagaaaact cagactgaac ccagaaatcg ccaaggggct cggctgtcaa ccactcgcag
     9721 gagcattcaa cctaaaacga agccgtctgc ggatcagaaa cgatctgtga ccttcattga
     9781 ggctcagcca gagccagcag ctgccccaac agatgcgctt cctgcaacag gccaactaca
     9841 gggctgtagc ccagcccctt ctaggaaacc agaagcaatg gacgaaccag tcctcacatc
     9901 ttctcccgcc atagttgttg cggatctcca cagcgtgtct cccaagcaga gtgagaactt
     9961 ccccactgaa gaaggagaaa aggaggagga cacagaagca caaggtgcta ctgcacacag
    10021 tccactctct gcccaactct ctgaccctga tgacttcaca ggcctcgaga catccagcct
    10081 cctacagcat ggagacactg tccttcatat cagtgaggaa aatggcatgg agaacccgct
    10141 actatctagt cagttcacct ttactcccac tgagctgggg aaaacggatg cagtattaga
    10201 tgagtctcat gtttaattct gtatcttgta agctctgcag gtatagagaa gacatgaaag
    10261 tgatctctct actacaagtt caatactttt gcttgaaaaa gattaattac aaaatagcac
    10321 tttacttcta atgggtggca caaatctgaa taggttttgc tgccaataca catgatgttt
    10381 cataaacatc ttaaaagtca atggctaaaa ggatttagtt gtgtgaaaat cacaaaacca
    10441 gggaggaata aggggaaaga gccatttcac tgcacattgt ttatgattca agaagccttc
    10501 agcagttaaa aatatatact attcattgct gctttcatag aaatattaac aaatgatatg
    10561 atctaaaaat agaatgcaat tttttgagat tactcacatt atacatctca tgcaaatatt
    10621 tatttttata gtttaaaaaa tatcaattca ggttggctat acaagtagca atttacataa
    10681 aaaaataatt aataggaaaa atattacttt ggggagacta aataacaagc ctgcagccat
    10741 ttttgttttg agtaacaata cagccattta gaagaagaaa aaaatactat atagagagct
    10801 gtggactttt agatatttat ttttcaacta tcattttcat tgcatgttgt aaatcaaaat
    10861 gcagatggca taagatcatc ccatttcata atctatcaca ttagaatatt acagaatatt
    10921 ctagaaatca tcagaaataa ttctgaatta agaacctaaa cagcctatac aattataaaa
    10981 actaaatgta tatataatca cttaaaagag atggtattcc tattcctagc cctgactaca
    11041 tcaataccaa gattagaagc tattggaaaa tgtgattagt aatacttttc cttatagtat
    11101 cctgtgcctg ccctggaggg catattttca gatattaagg ttagtgttgt tagaatcggt
    11161 ttaataaaat aacattttcc taatagaaac aatattctta tgatacttgg aacatctaag
    11221 tttataagga aaaatgtata aagtaagcaa tttcttcata gacacctcca gtttatatat
    11281 tttgcaaata ggcctttaac ttgaagttca attacttcaa gaaaagtgta acacttagaa
    11341 ggcttgtgag gccaacacct agtgtgttac tgatcctatg gtagggctgt gcatcacgtg
    11401 gttcacaatt gaatttcaaa attttaacag tttacattag aaaactgtta cctaacaacc
    11461 aagcatatac aaactcatat acatacttaa attggtacgg tggtgtatgt gtgcgtgcgt
    11521 gtgtgtgtgt atgtgttgta gtcctcaaga tgaagttaaa tatagacttt aattaccctg
    11581 caatgaattt aaaacacatt ctgtatgctt aaactttgag tgcgttggct gtgaaatgta
    11641 tacatatata aagaggatac ctactaaacc caccttaatc ataaaggaaa attatttttt
    11701 gttagaattg cttattaaat aggcatactt tatactgtgg tttataattt caaatataac
    11761 ttggggttat ggtcctattc actaagagaa tgaaagatat ccatgagtta aaagaacaaa
    11821 actaaaaatt tcagatctaa caattgaaag aaaattgagg cagtaaatga cctcttttac
    11881 tcttttatgt tttacaatat tatcatgtta tttacagtta atgctgaaat aattctcaag
    11941 tgcaggaata taaatgttaa gtggttttat gattccaagc tgatatattt cacctgttaa
    12001 aaattatgct gctaaattag cattagaggc cttatgtttg gtaattacaa gtgtctgggc
    12061 tattggcgcg tctctatata tgtgtgtgct ttgttccagt ttcttcaaat tatctatgta
    12121 taattgtatg aaatatttaa atagcaaaga agtcaaagaa gattgttaaa tattcaacaa
    12181 gaatcataaa tacctttata tgtattttaa aagtattggg ctgttctgaa catgattatg
    12241 ctggtctgtc tgtcttttag cctgactcct tcactcttgt gtgtgaagtc tattagcaac
    12301 tttcaataag ctaagcaatg ttgtaacttg caaaaaagcc tccactctga gaaacagggc
    12361 cttatagagt aggaatgttt tcatactggg actactgaaa ttttgcagat gtgtgcatct
    12421 gttccattta aggtgccctt aaatgtgttg aatgtaatgt gttgaatgtt tatgtgtaat
    12481 ggctaaagta tctatatgta tgtgcataaa actgtcacaa gatgtattct caggaatact
    12541 gttacctgga gtttgaaagg aataactatt aaaaaaaaaa gttggggaag attagaaaaa
    12601 agctcaagat aaatgttcaa aatattatta agtacatgac taaaagctaa ttactacata
    12661 tgataaatgc agtgttggta atagtagatc atttcttaag ccatgatact taatgatatt
    12721 tatcttattc agaggaaaaa caaaaaaggt acccacttcc catgtagaaa aaattagact
    12781 cagcaaagag gttgcttctt ctgaaattag cttttgagag accttggaat aaaccatgtg
    12841 ttatccatga tagtatgact cagatccaat taaaacagtt taaattctgg atataggatc
    12901 tcctatagca aaacatttta ctttcatttt tcagtatttg ctgctttcta gaattctatt
    12961 agataagcta tgtcattttt ctgaaaaaga aactgagtta ttgagtgtat taagacaagg
    13021 cactgagaac tacagtgtca aaatcaaagg gcataaatgg gcatggcagt gctggtggaa
    13081 aaatctgtgg tactggtgat ctggttaggg cctgttgcac aggctgggag taactggttt
    13141 gctgtttcaa gcctccaaga gtaccttaaa caaggtgata gctcctctct tctttagcat
    13201 tatattcctt tagtcaacaa agaactttct ccactctgct gcccagctct gagagtatct
    13261 gagatgagaa taggatgtgt gtggaggggc ttttagggaa gaaagggtca taaatgaata
    13321 gaagtacagt ctgaaacatg aattaaatat ccttcctcaa gttataaagg atactttaat
    13381 agaacacagt ctccagaatt cgctgctatc acaccaagtc atgctgttgc cctgtgacct
    13441 cacacttccc attccatggc cttgtcttgg cagggagtaa aaaatcccac ttctttttac
    13501 tttagtgggt ctcaactgca gcatttcaga aacaaatttt gatttgacac tcaggagaat
    13561 aaaaacaagt tgagggcaga atgtatttgg aaaagcttaa gacaaattta ctgatattat
    13621 tttatgatca tttaggatta cagatcaatt tacctccata aatctttgaa ttgtcactgt
    13681 gaccacagga tgaaaatcct ttattagcca ttttataggt taaaacaaaa aattgactac
    13741 acagccgact tccctcagat aactatgaag tctattatga gtactgaatg accaaagaac
    13801 atggaaaaaa tgcatatgaa taaatactga aatgtttatg aaagatattt atgaaagata
    13861 ttaagacttc tgtgtttagg tatgcacata tgataaaata aatctaaaaa cattaaa
//
